Monthly Archives: July 2020

Bayside Corners: Contrast and compare the French and U.S. healthcare experience – Mad River Union

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Its a slow Bayside news week, so I thought Id share a personal tale from some Bayside residents.

My husband Tom and I went out for our first restaurant meal together since early March. El Chipotle, in the Sunny Brae Center, is open every day for dine-in lunch and dinner. It has a sheltered outside patio, a huge indoor space, all of the recommended COVID precautions, and it felt very safe. What a small special pleasure in this strange time.

That got me thinking about things that we take for granted. This time last year, Tom and I were headed to southern France for a vacation with family. Three days in, on a very quiet Sunday morning in a small town along the Canal du Midi, Tom began feeling unwell... short of breath, pain in his upper arm. I was able to call Frances version of 911 and a short time later, an ambulance arrived, with a doctor (!), nurse technician and driver, and a second back-up vehicle.

Tests performed on site told them that he should go straight to hospital, and we were given the option of the closest, smaller hospital, or larger facility about 30 minutes away. We chose the latter.

Long story short, Tom was in various health care facilities for the next six weeks. He spent the first nine days at a hospital in Carcassonne. They did the angiography and all of the necessary tests so he could be assessed for surgery. He felt perfectly well during all of this time (in the U.S., Im sure he would have been discharged), but the French doctors wanted him supervised.

We were sent by medical taxi to consult with the cardiac surgeon and then transferred to a huge university hospital with a cardiac specialty unit in Toulouse, where he spent two weeks. He had quadruple bypass surgery, was five days in Cardiac ICU and then a regular cardiac unit. He was then transferred by medical taxi to a rehab facility where he spent another two weeks (they wanted him to stay a full month, but we needed to get home).

Throughout all this I stayed nearby and visited every day (by bus and metro) and, toward the end, on the weekends, we went out for excursions in the beautiful city of Toulouse. By this time, Tom was easily able to walk many miles a day, navigate stairs, and so on.

So what was so unusual about all this? Almost everything.

First, continuity of care. When the emergency occurred I contacted our medical provider and insurances at home. But I couldnt get any information. No one could tell me what would happen if I transferred Tom back to the U.S. for care. Where should we go? How would the surgery get authorized and scheduled? When could it be done? What would it cost?

That lack of clarity led us to stay in France where all of this was absolutely seamless. The French doctors themselves urged us to stay as they didnt trust this aspect of the U.S. system.

Second, the style of care. I was immediately struck by the difference in how medical staff interacted with patients. There was a lot less time spent looking at computer screens and entering information. Patients were encouraged to move around as much as they were able. It was common to see patients toting IV poles down in the cafeteria with family.

When I later saw Toms medical records, I was astonished at how concise and clear they were. When I once requested my own records from a two-hour $3,500 ER visit here at home, I received about 30 pages of gobbledly-gook.

Third, the cost. I was able to put the cost of the first nine days stay on a credit card while I sorted out the details. Would your credit card cover that in the U.S.?

We have long kept an emergency travel medical policy, renewed annually, which covers emergency medical evacuation (which could have been used in this case) or treatment. (Frequent travelers out there, I strongly recommend such policies which are incredibly cost-effective and the staff at ours was amazing in working with us to cover costs and get us home safely.)

When all was said and done, the total cost of all of Toms care, from ambulance to diagnosis to transfer to major surgery to rehab (six weeks in all) was less than $50,000.

The care was state-of-the-art. There was no process of authorizing and tracking every procedure, lab test and medication. If the doctors felt it necessary, it happened, and it was included in a flat daily rate for the level of care. The fee schedule for the first hospital was one half-page long.

When we were ready to go home, our insurance covered first class flights to San Francisco. The cost for those two tickets for a half-day plane ride was over $32,000!

It really makes me wonder about priorities... and to realize how lucky we were that Toms emergency happened in France... even if we did miss out on our vacation.

This column is normally about Bayside news (or the activities of Bayside residents). Got something to share? Contact bayside[emailprotected] or (707) 599.3192.

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Bayside Corners: Contrast and compare the French and U.S. healthcare experience - Mad River Union

Prime Healthcare Hospitals Named Among the Nation’s 100 Top Hospitals by IBM Watson Health, Five Receive Everest Award – GlobeNewswire

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Ontario, Calif., July 10, 2020 (GLOBE NEWSWIRE) --

Six Prime Healthcare hospitals have been named to the Fortune/IBM Watson Health 100 Top Hospitals list, which recognizes the top performing hospitals in the nation. With this years recognition, Prime Healthcare hospitals have ranked among the nations 100 Top Hospitals 53 times.

Five of the six hospitals honored this year have received an Everest Award, which recognizes hospitals that have earned the 100 Top Hospitals designation and ranked among the top 100 hospitals in the nation for rate-of-improvement during a five-year period.

The six Prime Healthcare hospitals on this list demonstrate a relentless commitment to high value, patient-centered care and innovation, said Ekta Punwani, Leader, 100 Top Hospitals Program. Year over year, Prime Healthcares staff, nurses and physicians demonstrate their focus on providing the highest-quality and safest care that results in this national recognition. This year, unlike any other, the COVID-19 crisis will be a catalyst for reinvention, and we believe these top performing Prime hospitals are positioned to emerge stronger and smarter out of this crisis.

East Liverpool City Hospital in East Liverpool, OH, is a three-time 100 Top Hospital honoree and recipient of the Everest Award for the third year in a row. Mission Regional Medical Center in Mission, TX; Saint Marys Regional Medical Center in Reno, NV; Providence Medical Center in Kansas City, KS and St. Marys Medical Center in Blue Springs, MO also received the Everest Award. Sherman Oaks Hospital in Sherman Oaks, CA, is a four-time 100 Top Hospital honoree.

The Everest award is a remarkable recognition and for five of our hospitals to earn this award speaks to the unwavering dedication to service excellence and patient centered care of our staff and physicians,said Sunny Bhatia, MD, Chief Medical Officer for Prime Healthcare. Many of these hospitals have been transformed as members of Prime, and this national recognition reflects our model and mission of saving hospitals and ensuring they deliver the highest quality of care to their communities. This mission has been especially critical during the COVID-19 pandemic, and we are committed to emerging better and stronger and grateful to all those that commit themselves to providing exceptional care.

Compared to similar hospitals, the hospitals included on the list had better results on performance indicators intended to measure clinical outcomes, operational efficiency, patient experience and financial health.

The outcomes include survival rates, patient complications, healthcare-associated infections, 30-day mortality and 30-day hospital-wide readmission rates, length of stay, throughput in emergency rooms, inpatient expenses, profitability, and ratings from patients.

Performance by these hospitals, when extrapolated to all Medicare inpatients, could result in:

To determine the hospitals included on the Fortune/IBM Watson Health 100 Top Hospitals list, IBM Watson Health researchers evaluated 3,134 short-term, acute care, non-federal U.S. hospitals.

All research was based on the following public data sets: Medicare cost reports, Medicare Provider Analysis and Review (MEDPAR) data, and core measures and patient satisfaction data from the Centers for Medicare & Medicaid Services (CMS) Hospital Compare website.

About the IBM Watson Health 100 Top Hospitals Program

The IBM Watson Health 100 Top Hospitals Program's annual studies result in the Fortune/IBM Watson Health 100 Top Hospitals list, IBM Watson Health 50 Top Cardiovascular Hospitals list and IBM Watson Health 15 Top Health Systems list. Organizations do not apply or pay for this honor or pay to promote their award. Award-winning hospitals and health systems serve as a model of excellence for the industry. Visit http://www.100tophospitals.com/ for more information.

About Prime Healthcare

Prime Healthcare is an award-winning national hospital system with 45 acute-care hospitals and more than 300 outpatient locations providing nearly 40,000 jobs in 14 states. Fifteen of the hospitals are not-for-profit and members of the Prime Healthcare Foundation, a 501(c)3 public charity. Based in California and one of the largest hospital systems in the country, Prime Healthcare is committed to ensuring access to quality healthcare. Prime Healthcare and its hospitals have been recognized as among the "100 Top Hospitals" in the nation 53 times and among the "15 Top Health Systems" three times. For more information, please visit http://www.primehealthcare.com.

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Prime Healthcare Hospitals Named Among the Nation's 100 Top Hospitals by IBM Watson Health, Five Receive Everest Award - GlobeNewswire

Patients want to continue using telehealth even after pandemic ends – Healthcare Finance News

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Patients have embraced virtual care and telehealth at very high rates as a result of COVID-19, and nine out of 10 said the quality of care was as good as or better than before, according to findings of a global Accenture survey of 2,700 oncology, cardiology and immunology patients.Sixty percent said that, based on their experience during the pandemic, they want to use technology more for communicating with healthcare providers and managing their conditions in the future.The survey was conducted in May across China, France, Germany, Japan, the U.K. and the U.S. at a time when all participating countries were under some degree of government restrictions as a result of the global pandemic.

WHAT'S THE IMPACT?As restrictions came into effect, patients faced difficult choices about whether and how to continue their treatments. Many healthcare providers cancelled appointments, and transportation options were shut down. Patients were afraid to risk exposure to COVID-19 by going to their healthcare providers for regular treatment, and as many as 70% deferred or cancelled at least some elements of their treatment.

But nearly half of all patients also started getting some treatment at home instead of going to their provider's office, and they began using virtual telehealth tools such as video conference calls, online chat and apps. Sixty-three percent of those who used video conferencing said it was very good or excellent an impressive response given 70% were using video conferencing for treatment for the first time. By using technology to support communication and care, providers were largely able to maintain or even improve on the patient experience.

Forty-seven percent of respondents said they received better, more personalized responses; 41% said responses were quicker;and 40% said it was more convenient to access care through new communications channels.Also, overall trust in the healthcare system has increased. Sixty percent of patients surveyed said their trust in healthcare providers has increased, and 45% said their trust in pharmaceutical and medical device companies has increased.

Worryingly, many clinical trials were disrupted by COVID-19. Seventy-seven percent of patients said their clinical trials were suspended or delayed, which could have an effect on the speed with which new treatments come to market.But for trials that continued, the use of telehealth was critical for consultations, treatment and monitoring. Case in point: 61% of patients whose trials continued used some form of virtual communication or care.

Patients said they want to be consulted more, but they are currently far from the center of the clinical-trial-design process. As decisions were being made on how to modify clinical trials due to COVID-19, only 14% of surveyed patients were asked about what changes would work for them. This held true across all therapeutic areas and geographies.

THE LARGER TREND

For insurers to continue covering telehealth after the public health emergency ends, policymakers should allow for flexibility in benefit designs, America's Health Insurance Plans said this week.

Telehealth visits should also be clinically comparable to in-person care and be countedtoward network adequacy requirements, risk adjustment calculations and quality measurement, the group said.

Centers for Medicare and Medicaid Services Administrator Seema Verma said Thursday morning that the agency is doing what it can to maintain telehealth in the healthcare system, for which the Trump Administration has expressed support.

Regulatory barriers to telehealth access include restrictions around geography, originating sites and state licensure requirements.

Federal policymakers have enacted more than 30 changes to enable greater access to telehealth, and,in a June hearing, members of the Senate Committee on Health, Education, Labor and Pensions examined how many of those changes should be made permanent and how to make sure the most vulnerable won't get left behind.

Twitter:@JELagasseEmail the writer:jeff.lagasse@himssmedia.com

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Patients want to continue using telehealth even after pandemic ends - Healthcare Finance News

Hyundai Donates Over 20000 Face Masks to Montgomery Area Healthcare Providers and Community – Alabama News Network

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Posted: Jul 10, 2020 10:48 AM CDT

Updated: Jul 10, 2020 2:25 PM CDT

by Alabama News Network Staff

Hyundai Motor Manufacturing Alabama (HMMA) has donated 20,000 face masks to the Montgomery County Emergency Management Agency (EMA), as well as 400 acrylic face shields to Montgomery area health care providers.

HMMA donated 20,000 form-fitting, washable fabric face masks to the Montgomery County EMA for community distribution via the Montgomery city council and the Montgomery county commission. Each city councilor will make the masks available for community events, neighborhood associations, and citizen requests.

Additionally, 200 acrylic face shields were donated to Baptist Health and 200 were donated to Jackson Hospital. With a national shortage of face masks available for medical personnel, plastic face shields serve as an extra layer of protection for doctors and nurses wearing surgical or fabric face masks.

Together, we will come out of this crisis stronger than ever, said Robert Burns, HMMA vice president HR & administration. While navigating the impact of COVID-19 , team member safety has been a top priority in getting us back on our feet producing high quality vehicles for the entire North American market . We feel it is our duty to help get our home community of Montgomery, which has been so severely impacted, back on its feet as well.

Montgomery has always been stronger together, and public-private partnerships with community stakeholders like HMMA are the bedrock of our success, said Montgomery Mayor Steven L. Reed. These relationships will be integral in building out our vision for a better Montgomery in the aftermath of the COVID-19 pandemic. Through this donation, Hyundai again demonstrates its commitment to our people. We commend HMMAs leadership and hardworking team members for standing steadfast with our city as we work to stop the spread of COVID-19. We cannot thank them enough for another outpouring of generosity with the donation of 20,000 masks to those in need in Montgomery and central Alabama.

Montgomery Emergency Management Agency humbly thanks our continued HMMA partnership as our Montgomery Community mitigates the spread of COVID-19, said Christina Thornton, Montgomery County EMA director. The more we come together the stronger our Montgomery will be. Please help stop the spread and Mask-Up!

We are so grateful for Hyundai Motor Manufacturing of Alabama for recognizing the continued need to promote precautionary masking in our community, said Tommy McKinnon, Baptist Health vice president of community engagement.

We are equally appreciative of HMMAs contribution of protective face shields to our hospitals, which will greatly help with ongoing personal protective equipment needs.

Earlier this year HMMA donated 450 box lunches to Montgomery area front line health providers,1,000 surgical masks to the Alabama Dental Association and 10,000 COVID-19 tests to Montgomery and surrounding counties to support drive through testing in Alabama.

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Hyundai Donates Over 20000 Face Masks to Montgomery Area Healthcare Providers and Community - Alabama News Network

Trump Health Secretary Says US Healthcare Workers ‘Don’t Get Infected’ With Covid-19 (94,000 Have Contracted the Virus) – Common Dreams

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Health and Human Services Secretary Alex Azar on Tuesday falsely claimed that healthcare workers "don't get infected" with Covid-19 "because they take appropriate precautions" as he attempted to make the case for reopening schools in the falleven with coronavirus cases surging across the United States.

"If we don't have enough PPE for the healthcare workers on the front lines, how can we possibly have enough PPE for all of the country's teachers to take the same precautions?" Sarah Karlin-Smith, Pink Sheet

"There's no reason we can't do any of this," Azar, a former pharmaceutical lobbyist and executive, said during an event at the White House. "We have healthcare settings. We have healthcare workers, they don't get infected because they take appropriate precautions. They engage in social distancing, they wear facial covering, they use good personal hygiene. This can work, you can do all of this. There's no reason schools have to be in any way any different."

In addition to noting that Azar's claim about healthcare workers not getting infected is wildly falseaccording to the Centers for Disease Control and Prevention, more than 94,000 healthcare workers have contracted Covid-19 and at least 500 have diedmedical professionals rejected the argument that precautionary measures taken in healthcare settings can easily be replicated in the nation's schools.

"We are trained in infection control and have used [personal protective equipment] for years," tweeted Prasad Jallepalli, MD, a professor at the Memorial Sloan Kettering Cancer Center. "This is almost as dumb as the 'give teachers guns' proposal."

Sarah Karlin-Smith, a reporter with Pink Sheet, asked: "If we don't have enough PPE for the healthcare workers on the front lines, how can we possibly have enough PPE for all of the country's teachers to take the same precautions?"

Watch Azar's remarks:

In response to widespread criticism of Azar's comments, HHS spokesperson Michael Caputo tweeted that the secretary "is keenly aware of and grateful for the sacrifices #HealthcareHeroes have been making throughout this pandemic" and added that it would be "foolish" to suggest he "doesn't believe these warriors get sick and die."

Kaiser Health News and The Guardian, in a collaborative investigation titled "Lost on the Frontline," identified more than 760 healthcare workers who have likely died of Covid-19 in the U.S.a death toll significantly higher than the CDC's official count.

"In some states, medical personnel account for as many as 20% of known coronavirus cases. They tend to patients in hospitals, treating them, serving them food, and cleaning their rooms. Others at risk work in nursing homes or are employed as home health aides," the outlets reported. "Some cases are shrouded in secrecy... Many hospitals have been overwhelmed and workers sometimes have lacked protective equipment or suffer from underlying health conditions that make them vulnerable to the highly infectious virus."

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Trump Health Secretary Says US Healthcare Workers 'Don't Get Infected' With Covid-19 (94,000 Have Contracted the Virus) - Common Dreams

Health-care unions considering political action over Ontarios emergency act – The Globe and Mail

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Unions representing Ontarios health care workers say theyre consulting with their memberships about taking political action in response to the province potentially extending its emergency powers.

The Ontario Council of Hospital Unions, a division of the Canadian Union of Public Employees, said that under the emergency orders, their collective bargaining agreement with the province is suspended.

The Progressive Conservative government introduced a bill earlier this week that would allow the province to keep some emergency measures in place in the months ahead.

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Michael Hurley, president of the OCHU, said that while that was acceptable in the early stages of the COVID-19 pandemic, its now a detriment to health care workers.

The act makes it clear that the emergency is over thats explicit in the legislation, Mr. Hurley said. The case count in Ontario has dropped dramatically. The number of cases is perhaps a fifth of what it was in March when the emergency was declared.

As of Friday, there were 117 patients currently hospitalized with COVID-19 in Ontario, down from a peak of 1,043 in March. There were 4,309 active cases in the province, according to the Ontario government.

Mr. Hurley said that with the emergency orders in place, nurses and other care workers can have their shifts changed, be moved from site to site or have vacation requests denied. He also pointed out that the act applies to the entire province, but many public-health units are out of an emergency situation.

Health Minister Christine Elliott said on Friday that 30 of the provinces 34 public-health units every region except Peel, York, Toronto and Windsor-Essex are reporting five or fewer new cases, with 17 of them reporting no new cases at all.

The health care worker unions said they will have meetings with executive board members, stewards and members over the weekend and on Monday to decide on a course of action by Tuesday. Options available to the membership range from wearing stickers to work, organizing a rally or even an interruption of work.

What is the most painful thing of this is that no one wants to turn their attention from providing patient care to having to defend some basic workplace rights, Mr. Hurley said. Thats the last thing anyone wants to do, so were hoping that the government reconsiders its position.

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The union also said the Ontario government announced its plans to extend the act without consulting them.

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Scores forecast effects of mutations in autism gene – Spectrum

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Mutation rating: Scores may help researchers identify changes in the gene PTEN most likely to play a role in autism.

CRAFTSCI / Science Photo Library

A new analysis links individual mutations in a gene called PTEN to a persons odds of having autism, cancer or other conditions1. The findings may help clinicians and researchers predict the effects of various mutations in the gene.

PTEN controls cell growth and regulates the strength of connections between neurons. Mutations in the gene are associated with a variety of conditions, including autism, macrocephaly (enlarged head size), benign tumors and several types of cancer. It is still unclear how different mutations cause such varied effects.

Scientists cannot easily predict the consequences of a PTEN mutation based on its type whether it involves a single amino acid change or a larger interruption to the gene, for example or its impact on the protein the gene encodes. Researchers have developed methods to examine the molecular effects of PTEN mutations within cells in a dish, but these approaches do not link mutations to specific conditions in people.

In the new analysis, the researchers probed the effects of 7,657 PTEN mutations, representing all possible changes to each amino acid in the genes sequence. They built on the findings from a previous study in which they used yeast cells to calculate a fitness score for 7,244 PTEN mutations2. They combined this dataset with another in which researchers had given an abundance score to 4,112 PTEN mutations based on how those mutations affect protein levels in human cells in a dish3.

The team used machine learning on the combined dataset to calculate abundance and fitness scores for mutations that lacked them. They then compared these scores with data they gathered from 421 people with PTEN mutations 165 controls and 256 people with a PTEN-related condition, such as autism, developmental delay, intellectual disability, macrocephaly, or benign or malignant tumors.

People with the largest head size tend to have mutations with the lowest fitness and abundance scores, the researchers reported in June in the American Journal of Human Genetics. Similarly, low scores track with having PTEN-related conditions that are severe or appear at a young age.

By comparing mutations in individuals with PTEN-linked traits and those in controls, the researchers also found that fitness scores can predict whether a mutation is likely to lead to a PTEN-related condition.

Together, these findings suggest that abundance and fitness scores may help predict the consequences of PTEN mutations, the researchers say.

The team also split single amino acid changes into three classes based on the severity of their effects on protein function and abundance.

The most severe mutations are linked to a higher likelihood of cancer diagnosis by age 35 compared with the least severe mutations, the researchers found. Greater severity also tracks with an increased likelihood of tumor-like growths.

However, the severity of the variants effects is not tied to a persons likelihood of having autism or developmental delay. This suggests that even a small decrease in PTEN activity may be enough to significantly increase the odds of having a neurodevelopmental condition, the researchers say.

The analysis may help tease apart PTEN mutations different effects, the researchers say. It may also help researchers identify the mutations most likely to play a role in autism and prioritize them for further research.

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Scores forecast effects of mutations in autism gene - Spectrum

Herd Immunity Is A Distant Dream- Antibodies May Disappear From An Individual’s Body Within Weeks – Inventiva

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It will take around five months for the US, 22 months for the UK, and about one year in Italy for the people to attain herd immunity.

Now if you are completely oblivious to the fact of what herd immunity is, let us help you out. When a persons immune system is attacked with an unknown virus, the antibody production starts at a mass level. When the person recovers from the ailment, and immunity is developed known as the herd immunity. So for the herd immunity to develop as a whole, in a population of about 100 percent, about 80 percent of people have to be attacked with the same virus so that they can produce rapid antibodies.

The novel coronavirus continues to spread at an alarming speed and has infected near 12 million individuals. There is, while the pros are studying more about the operation of the contagion with each day. The fresh price of research has suggested that achieving a level of herd immunity among the crowd can be pretty difficult to attain in a few weeks or even months. While there is an ongoing debate going on among experts, most of them are split about the decision or the time limit as to when shall herd immunity be the only option among crowds. It is surely an achievable foot but it will take time to happen as more and more population are suspected to be tested as positive.

In a study performed in Belgium, scientists assessed the feasibility of creating herd resistance in a population without burdening the ICUs. The investigators used an online tool out of about-the-curve. Net along with also the SIR (Susceptible-Infected-Recovered) version for the spread of illness to estimate that without burdening the ICUs, it might take about 5 weeks to the US, 22 weeks to the UK and roughly a year for Italy to grow herd immunity.

The team works on human genetics, bioinformatics, AI, and machine learning. Besides, he teaches bioinformatics focusing on approaches in biology.

The UK had suggested the idea of herd immunity when the number of cases improved in the nation, but there was a lockdown set in place. The research is still in development and peers are asked to review it before it can be sent to the officials.

Its thought that herd immunity could be achieved for specific ailments when most cases have grown immune and 40 percent of the populace is infected with the disease. But in the majority of cases at 80 to 90 percent of the populace should grow immunity (through vaccination or becoming infected) to halt the illness from spreading farther. Experts around the globe hoped to go in effect to allow its contagion, for the novel coronavirus.

In a recent study which is conducted in Spain, about only 5% of the people have developed protective antibodies for the novel coronavirus. But this is completely on the papers and not published yet. Since the figures were drawn on a previously based study, scientists are still counting the number of people who are yet to develop rapid antibodies inside them. It is even suspected that 40 percent of the people are slowly healing without having to develop symptoms.

The study underlines that although Spain is still one of those nations that are worst-hit by the coronavirus from the entire world, 95 percent of its inhabitants are prone to the book coronavirus. The report further reads, Spain is taken as an example since the extreme outbreak of the coronavirus pandemic happened initially at this place. Now that the curve is flat, scientists are finding it that if the population have achieved levels of herd immunity or not. At the Moment, herd resistance is hard to reach without accepting the security damage of deaths in the vulnerable people and overburdening of health programs

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Herd Immunity Is A Distant Dream- Antibodies May Disappear From An Individual's Body Within Weeks - Inventiva

Explained: A new calculation to find your dogs age in human years – The Indian Express

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Written by Kabir Firaque, Mehr Gill | New Delhi | Updated: July 9, 2020 7:34:11 am There exists a very simple thumb rule, used frequently over the years. The new research, however, has described it as a myth

Dogs live shorter lives than humans, and so a six-year-old dog is at a far later stage of its life than a six-year-old child. A dog can even be a grandparent at age six. What, then, is its age in human years? New research, published in the journal Cell Systems has come up with a formula and a graph to determine that.

Was there not a formula already?

There exists a very simple thumb rule, used frequently over the years. The new research, however, has described it as a myth. According to the popular rule, you multiply a dogs age by 7, and you supposedly get its equivalent age in human years: For example, a four-year-old dog is 28 in human years. Only, its not so simple.

Why not?

The new research, which is based on epigenetics, has found the comparison between human years and dog years is not perfectly linear which would have been the case had the 1:7 thumb rule been reliable. The relationship, in fact, follows the red curve shown in the figure.

How can I use this curve to determine my dogs age in human years?

First, find your dogs age along the horizontal (X) axis. Suppose your dog is four years old. Locate 4 on the horizontal axis, then trace your finger upwards until you reach the red curve. From that point, move left towards the vertical (Y) axis, where you have human years (illustrated with Tom Hanks at various ages). Your finger will touch the vertical axis at, in this case, 52 years.

So, a four-year-old dog is equivalent in physiological age to a 52-year-old Tom Hanks (or any 52-year-old human). This is almost twice as much the age you would get (28) if you followed the 1:7 thumb rule.

What is the basis of this new calculation?

It is based on molecular changes in the human genome and dog genome over time. Researchers at the University of California at San Diego analysed patterns over time in methylation a term that refers to specific chemical changes in the genome.

This is the field that is known as epigenetics, which studies chemical modifications that influence which genes are off or on, without altering the original genetic sequence itself. The new formula, the researchers said, provides a new epigenetic clock for determining the age of a cell, tissue or organism.

How did the researchers derive the formula?

The UC San Diego team had previously published epigenetic clocks for humans. For the new study, they collaborated with dog genetics experts at UC Davis and the US National Human Genome Research Institute. They analysed blood samples from 105 Labrador retrievers for changes with age.

Only Labradors?

Indeed, that is one limitation of the new epigenetic clock, acknowledged by senior author Trey Ideker himself. (The first author is Tina Wang, Idekers former graduate student, who first suggested the idea for such a study.) In a statement, Ideker acknowledged that the new epigenetic clock was developed using a single breed of dog, and some dog breeds are known to live longer than others. More research will be needed, he said.

Will it work for my dog if it is not a Labrador?

Ideker said it is accurate for humans and mice, as well as Labrador retrievers. He predicts that the clock will apply to all dog breeds. As such, it may provide a useful tool for veterinarians and even for evaluating anti-ageing interventions, the researchers suggest.

How so?

There are a variety of anti-ageing interventions in the market, with some of these standing on a more solid scientific foundation than others. But, as Ideker noted in the statement, how do you know if a product will truly extend your life without waiting 40 years or so?

If you refer to the new epigenetic clock, you need not wait, he suggested. What if you could measure your age-associated methylation patterns before, during and after the intervention to see if its doing anything?

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Explained: A new calculation to find your dogs age in human years - The Indian Express

SETI in the News Media Roundup May 16 June 30, 2020 – SETI Institute

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Martian Moons Orbit Hints at an Ancient Ring of Mars

Scientists from the SETI Institute and Purdue University have found that the only way to produce Deimoss unusually tilted orbit is for Mars to have had a ring billions of years ago. While some of the more massive planets in our solar system have giant rings and numerous big moons, Mars only has two small, misshapen moons, Phobos and Deimos. Although these moons are small, their peculiar orbits hide important secrets about their past.

Researchers from the University of California Berkeley and other organizations, including the SETI Institute, released the most extensive collection of images showing debris discs around young stars, providing a glimpse of what our solar system might have looked like when its planets were forming. The images were part of data collected over four years by the Gemini Planet Imager (GPI), located on the Gemini South Telescope in Chile.

Citizen science pioneers recently made two contributions to a better knowledge of outer space. Backyard astronomers of the SETI Institute and Unistellar network conducted in April citizen science observations, and their discoveries will improve our understanding of asteroids and exoplanets. Thanks to their work, we know precisely the location of the main-belt asteroid 2000 UD52 and have confirmed an exoplanet transit of Qatar-1b.

Its anyones guess how many alien civilizations could be out in the cosmos. Experts recently weighed in with numbers ranging from 36 to a thousand.

According to a new analysis from scientists at the University of Nottingham, we dont have a lot of alien company. On June 15, two researchers published a paper in the Astrophysical Journal arguing that the Milky Way which sports about 250 billion stars could host as few as 36 alien societies. Thats a small number, and rather less than the number of races that have appeared in Star Trek. The authors supplement their piddling tally with a second, more generous analysis in which they say that, OK, the count might be as many as a thousand. (Seth Shostak, SETI Institute Senior Astronomer)

Frank Drake, who recently turned 90, is a pioneer in the search for extraterrestrial life (SETI). 60 years ago, in 1960, he used an 85-foot radio telescope at the National Radio Astronomy Observatory (NRAO) in Green Bank, West Virginia, to make humanitys first attempt to detect interstellar radio transmissions.

He was the first to probe the skies in an unprecedented way in an experiment he called Project Ozma. Drake was looking for signs of cosmic company: the presence of other intelligent beings on planets around other stars. (Seth Shostak)

A historic piece of intergalactic communication will soon be ready for our listening pleasure.

A message that was first used in an attempt to contact intelligent life is now being turned into music. That's right, if you thought you'd seen it all when it comes to clever sampling and creative audio to MIDI conversions, Australian electronic duo,The Avalanches, are about to take things a step further.

It's unknown whether Frank Drake, creator of the 1974 Arecibo Message, envisioned his work being turned into a song several decades later, but that is exactly what's been teased in The Avalanches' latest post. (EDM.com)

Check out Weekly Space Hangout with astrophysicist Dana Backman, who manages the NASA Airborne Astronomy Ambassadors (AAA) program for the SETI Institute.

Rock from outer space is usually referring to a solid object, but not in this case. Researchers recently announced receiving radio transmissions from space in the form of classic rock music.

Expressing excitement over what could be a landmark discovery in the search for extraterrestrial life, scientists at the SETI Institute announced Tuesday they had received a mysterious radio transmission from space that repeats 50-minute intervals of nonstop classic rock blocks. We detected a signal emanating from hundreds of thousands of lightyears away that, once deciphered, we realized was all the best hits from Zeppelin, Aerosmith, and the Doors in a back-to-back commercial-free format, said SETI researcher Duane Hess, confirming that the transmission could potentially originate from an alien civilization of die-hard 60s, 70s, and 80s rock fans. (The Onion, satirical news)

In a recent Reddit Ask-Me-Anything (AMA), Pascal Lee of the SETI Institute and NASAs Haughton-Mars Project at NASA Ames Research Center described genetic testing on samples from beneath the surface as the best way to find alien life on Mars.

The only way to establish that life found on Mars is alien would be to do genetics on it and show that it does not belong to Earth's Tree of Life. In order to do genetics on it, we have to find it alive (or dead only very recently; not fossilized), he explained.

Until we explore the interiors of Mars' volcanoes (lava tubes) and/or drill deep into the Martian subsurface, we are unlikely to find any signature of life we can establish as alien, which is the main point of the search to begin with, he stated. No amount of fossil finding at the surface of Mars will tell you for sure that you've found alien life.

Big Picture Science

Laughing rats, sorrowful elephants, joyful chimpanzees.The more carefully we observe, and the more we learn about animals, the closer their emotional lives appear to resemble our own.Most would agree that we should minimize the physical suffering of animals, but should we give equal consideration to their emotional stress?Bioethicist Peter Singer weighs in. Meanwhile, captivity that may be ethical: How human-elephant teamwork in Asia may help protect an endangered species. Join guests Peter Singer, Frans de Waal, Jacob Shell and Kevin Schneider as we take a look at universal emotions in Animals Like Us.

Crowded subway driving you crazy? Sick of the marathon-length grocery store line? Wish you had a hovercraft to float over traffic? If you are itching to hightail it to an isolated cabin in the woods, remember, we evolved to be together. Humans are not only social, were driven to care for one another, even those outside our immediate family. Join guests Adam Rutherford, Patricia Churchland and Mark Moffett as we look at some of the reasons why this is so from the increase in valuable communication within social groups to the power of the hormone oxytocin.Plus, how our willingness to tolerate anonymity, a condition which allows societies to grow, has a parallel in ant supercolonies in Let's Stick Together.

Sexist snow plowing?Data that guide everything from snow removal schedules to heart research often fail to consider gender.In these cases, reference man stands in for average human.Human bias also infects artificial intelligence, with speech recognition triggered only by male voices and facial recognition that cant see black faces.Join guests Caroline Criado-Perez, Kade Crockford and Amy Webb as we question the assumptions baked into these numbers and algorithms in Skeptic Check: Data Bias.

While citizens take to the streets to protest racist violence, the pandemic has its own brutal inequities. Black, Latino, and Native American people are bearing the brunt of COVID illness and death. Join guests Marcella Nunez Smith, Utibe Essien, Nina Jablonski, Robert Sapolsky and Harold Frazier as we look at the multitude of factors that contribute to this disparity, most of which existed long before the pandemic. Also, how the Cheyenne River Sioux tribe maintained their coronavirus safeguards in defiance of the South Dakota governor. And, the biological reasons why we categorize one another by skin color in Race and COVID.

Some safeguards against COVID-19 dont require a medical breakthrough. Join guests Cody Cassidy, Nina Jablonski and Eti Ben Simon as they discuss catching sufficient Zs, sending viruses down the drain and how your first line of defense, your skin, is also neglected in Soap, Skin, Sleep.

Will Alexa laugh at your jokes or groan at your puns? In this episode, find out whats involved in tickling A.I.s funny bone with guest Julia Rayz, Steve Adler, Doug Vakoch and Richard Wrangham, as well as an interstellar communication challenge in Gained in Translation.

When can we expect a COVID vaccine? Guests Nigel Brown, Ian Haydon, Bonnie Maldonado and Paul Offit discuss timelines, how it would work, whos involved and the role of human challenge trials in Vaccine, When?

SETI Live

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As always, videos of all past Facebook Live events can be found on our Facebook page: https://www.facebook.com/SETIInstitute/

Or on our YouTube channel: https://www.youtube.com/SETIInstitute

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SETI in the News Media Roundup May 16 June 30, 2020 - SETI Institute

Idorsia announces positive results in the second Phase 3 study of daridorexant – GlobeNewswire

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Allschwil, Switzerland July 6, 2020Idorsia Ltd (SIX: IDIA) today announced positive top-line results of the second pivotal Phase 3 study investigating 10 and 25 mg doses of its dual orexin receptor antagonist, daridorexant, in 924 adult and elderly patients (39.3% 65 years) with insomnia. The study confirms the findings of the first pivotal study, demonstrating efficacy of treatment with daridorexant on objective and subjective sleep parameters and showed positive effects on daytime functioning, with patients reporting no morning sleepiness and no evidence of rebound or withdrawal symptoms upon treatment discontinuation.

On April 20, 2020, the company reported (media release) the results of the first pivotal study with daridorexant where both 25 and 50 mg daridorexant significantly improved both sleep onset and sleep maintenance. Daridorexant 50 mg also significantly improved daytime functioning. All results were sustained over the 3 months of the trial.

In the second study, daridorexant 25 mg significantly improved sleep maintenance as measured objectively in a sleep lab by polysomnography. Daridorexant 25 mg also significantly improved subjective total sleep time as measured daily with a patient diary at home. The results were statistically significant at month 1 and at month 3 for these sleep measures, showing sustained benefit.

Furthermore, the effect of daridorexant 25mg on sleep onset and daytime functioning were numerically consistent with the effects seen in the first study. However, due to the control of the Type 1 error rate for 16 comparisons, these endpoints despite the low p values did not reach statistical significance.

The 10 mg dose of daridorexant showed numerical improvements, across all efficacy measures, of a smaller magnitude than observed on 25 mg, none of which reached statistical significance.

The results of the two large pivotal studies, testing daridorexant at three doses from 10 to 50 mg, now provide a deep understanding of its efficacy and tolerability profile. Furthermore, the similar design of the two Phase 3 studies allows for the twogroups of25 mgandplaceboto be pooledanda pre-planned analysis to be made. This pooled analysis willfurthercharacterize the effect of daridorexant.

Guy Braunstein, MD and Head of Global Clinical Development of Idorsia, commented:

I want to start with a thank you to the study participants, investigators and their support staff, and the Idorsia team for delivering another comprehensive set of robust data. I am delighted to see the replicated effect of 25 mg of daridorexant in this large confirmatory study. The consistency of the treatment effect across both studies is remarkable. I believe the fact that daridorexant improves daytime functioning is a real breakthrough for patients. I am looking forward to the integration of all aspects of the program, including the pooled data, the long-term extension data, the clinical pharmacology program, and all that we can learn from the patient reported outcome instruments. There is a lot of work for us to do as we interact with the health authorities and share the data with the scientific community.

About safety in the studyThe safety profile was consistent with the results of the first study. Treatment-emergent adverse events (TEAEs) during the double-blind study period were reported in 38.2% and 39.3% of the patients treated with 10 and 25 mg daridorexant, respectively (32.7% for placebo). The most frequent TEAEs reported over 3% incidenceand higher on 25 mg of daridorexant than placebo were nasopharyngitis, headache, somnolence and fatigue. The number of patients experiencing serious adverse events was low and balanced across treatment groups (10 mg, 3 patients; 25 mg, 3 patients; placebo, 4 patients). Based on independent blinded adjudication committee assessment, the number of patients reporting excessive daytime sleepiness as AE was low (10 mg, 1 patient; 25 mg, 4 patients; and placebo, 1 patient); 3 patients had AEs of special interest related to sleep paralysis and hallucination. No events denoting cataplexy-like events were reported or adjudicated. There was no next-morning residual effectas assessed every morning by the patients using a visual analog scale; 2 patients reported suicidal ideation (10 mg, 1 patient; 25 mg, 1 patient) with clear alternative causes; no suicide or self-injury were observed. There was no evidence of rebound insomnia, and no withdrawal symptoms upon discontinuation.

EmmanuelMignot,MD and Professor of Psychiatry and Behavioral Sciences at Stanford University, commented:The daridorexant program demonstrates the full potential of orexin receptor antagonism excellent effect and a good safety profile. It is exciting to see this, 20 years after the discovery of the role of orexin in sleep regulation. For me, the improved daytime functioning seen with daridorexant is most impressive. What is important to patients is not only to improve their night sleep but also how they feel during the day. By measuring the benefits of the drug through the day as well as through the night, the program has put patients back at the center of the equation and raised the standard for what we need to see with sleep medications. This ensures the patient need is at the center of prescription decisions when treating insomnia.

Jean-Paul Clozel, MD and Chief Executive Officer of Idorsia, commented:I was stunned by the excellent results of the first study with daridorexant, this time Im struck by the consistency of the efficacy results, including daytime functioning and the safety profile. I am very proud of the great science behind daridorexant and that Idorsia has designed and executed such a comprehensive program, focused on patients, in such a short time. I am convinced that with daridorexant, Idorsia has a unique drug which is going to have a disruptive impact on the insomnia market. The whole company is united in the effort to file the NDA with the US FDA around the end of this year and to prepare for a successful launch. There is certainly a lot of work to be done, but we are already making great progress on all fronts.

Detailed results of the Phase 3 studies will be made available through scientific disclosure at upcoming congresses and in peer-reviewed publications.

About the Phase 3 registration program

The Phase 3 registration program comprises two confirmatory studies of 3-month duration, together with a long-term extension study. Both pivotal studies are complete, having enrolled around 1,850 patients with insomnia at over 160 sites across 18 countries. As insomnia often presents later in life, around 40% of the recruited population was aged 65 years or older. The confirmatory multi-center, double-blind, randomized, placebo-controlled, parallel-group, polysomnography studies investigated three doses of daridorexant (10 mg, 25 mg, and 50 mg) on sleep and daytime functioning parameters, objectively in a sleep lab by polysomnography and subjectively with a daily patient diary at home. The impact of insomnia on patients daytime functioning was measured daily using the sleepiness domain score from the Insomnia Daytime Symptoms and Impacts Questionnaire (IDSIQ) a Patient Reported Outcome (PRO) instrument, validated according to the US Food and Drug Administration (FDA) Guidance for Industry. 806 patients decided to continue treatment in the ongoing 40-week extension study which will measure the effect of all three doses vs. placebo, generating data for long-term treatment of insomnia.

Investor webcastOn April 20, 2020, the company held an investor webcast to discuss the results of the first Phase 3 study with daridorexant. On that occasion, Martine Clozel, MD, Chief Scientific Officer presented a brief overview of the tailored drug discovery efforts that led to the synthesis of daridorexant. This was followed by Guy Braunstein providing an overview of insomnia, the objectives of the Phase 3 program, the methodologies used to measure the effect of daridorexant on patients with insomnia, and the results of the first study. This webcast is available for replay on the corporate website.

The company will hold an investor conference call and webcast to discuss the results of the second Phase 3 study with daridorexant. On the call, Guy Braunstein will present the study results, followed by a Q&A session with Jean-Paul Clozel, Guy Braunstein, and Martine Clozel.

Date: Monday July 6, 2020Time: 14:00 CEST | 13:00 BST | 08:00 EDT

Webcast participants should visit Idorsia's website http://www.idorsia.com 10-15 minutes before the webcast is due to start.

Conference call participants should start calling the number below 10-15 minutes before the conference is due to start.

Dial-in CH: +41 (0)44 580 65 22 / UK: +44 20 3009 2470 / US: +1 (877) 423-0830PIN: 24890393#

Notes to the editor

About insomniaInsomnia is a condition of overactive wake signaling that can have a profound effect on the lives of patients. Insomnia can be defined as difficulty falling asleep and / or staying asleep, occuring at least three times a week for a minimum of three months.

It is estimated that as many as one in ten people suffer from insomnia and its impact is often underestimated. In reality, it can be a distressing condition that can impair quality of life. Sleepless nights can leave people feeling irritable and out of sorts this may affect many aspects of daily life, from studying and employment to social activities and relationships. People who suffer from insomnia may lack the energy or motivation to exercise or to take part in social activities. It can also have a significant economic impact as it increases the risk of accident and injury on the road or in the workplace, and is a leading cause of absenteeism and reduced productivity at work. People with insomnia are more likely to experience feeling down or depressed, lack concentration, and suffer from poor energy levels during the day compared with people who sleep well. In addition, worrying about sleep can cause stress and may lead to negative thought patterns which may in turn make it more difficult to sleep, setting up a vicious circle. Chronic insomnia is associated with cardiovascular and cerebrovascular diseases, and increased mortality.

The goal of treatments for insomnia is to improve sleep quality and quantity, as well as reducing insomnia-related impaired daytime functioning, while avoiding adverse events and next morning residual effect. Current treatment of insomnia includes cognitive behavioral therapy, sleep hygiene recommendations, and pharmacotherapy. The most widely prescribed products on the market that are indicated for insomnia enhance the effects of gamma-aminobutyric acid (GABA), the major inhibitory neurotransmitter in the central nervous system. Such medications are only approved for short-term use and are associated with side effects such as next-morning residual effects, anterograde amnesia, and risk of tolerance and dependence.

About the orexin systemWake and sleep signaling is regulated by intricate neural circuitry in the brain. One key component of this process is the orexin system, which helps promote and consolidate wakefulness. There are two forms of orexin neuropeptides Orexin A and OrexinB. Orexin promotes wakefulness through its receptors OX1R and OX2R. In combination, these neuropeptides and receptors comprise the orexin system. The orexin system stimulates target neurons in the wake system leading to the release of several chemicals (Dopamine, Serotonin, Histamine, Acetylcholine, Norepinephrine) which promote wakefulness. Under normal circumstances, orexin levels rise throughout the day as wakefulness is promoted and then consolidated and fall at night. Overactivity of the orexin system is thought to be an important driver of insomnia.

Idorsias research team has been working on the science of orexin and orexin receptors since they were first described in 1998. The teams initial work led to the conclusion that antagonism of the orexin system was the key to preserving a natural sleep architecture for patients with insomnia. With this as the target the team started to design a dual antagonist with a rapid effect, and a duration of action sufficient for the night but short enough to avoid any negative residual activity the following morning at optimally effective doses.

About dual orexin receptor antagonismDual orexin receptor antagonists or DORAs are an entirely different approach to treating insomnia than previous drug classes, turning down overactive wakefulness by blocking the activity of orexin. DORAs specifically target the orexin system by competitively binding with both receptors and thereby reversibly blocking the activity of orexin. It is hypothesized that blocking orexin receptors reduces the downstream activity of the other wake promoting neurotransmitters that are overactive in insomnia, leading to the clinical efficacy demonstrated by orexin receptor antagonists.

Data supporting daridorexant in insomnia Results of the first Phase 3 study, investigating daridorexant doses 25 and 50mg, were reported in April 2020. The study demonstrated efficacy of treatment with daridorexant on objective and subjective sleep parameters and daytime functoning with no residual effect in the morning, and no evidence of rebound or withdrawal symptoms upon treatment discontinuation.

Daridorexant at both 25 and 50 mg significantly improved sleep onset and sleep maintenance as measured objectively in a sleep lab by polysomnography. Daridorexant also significantly improved subjective total sleep time as measured daily with a patient diary at home. The results were consistently statistically significant at month 1 and at month 3, indicating sustained benefit. Furthermore, treatment with daridorexant improved patients daytime functioning from baseline at month 1 and month 3.

The rate of adverse events was comparable between placebo and daridorexant at both treatment doses. Treatment-emergent adverse events (TEAEs) during the double-blind study period were reported in 37.7% and 37.7% of the patients treated with 25 and 50 mg daridorexant, respectively (34.0% for placebo). The most frequent TEAE reported over 3% incidence and higher than placebo was nasopharyngitis, headache.

Prior to the Phase 3 program, the safety and efficacy of daridorexant in adult and elderly patients with insomnia was evaluated in a comprehensive Phase 2 program, comprising two studies, one of which included zolpidem 10 mg as an active reference. Both studies showed the desired effect on sleep maintenance and onset, with a significant dose-response relationship; treatment was generally well tolerated.

A comprehensive clinical pharmacology program is being conducted totaling approximately 20 studies and including, amongst others, studies assessing abuse liability, drug-drug interactions, next-morning driving, the effect of daridorexant on respiratory function in patients with chronic obstructive pulmonary disease (COPD) or obstructive sleep apnea (OSA), and the pharmacokinetics of daridorexant in patients with liver and renal impairment.

EmmanuelMignot,MD and Professor of Psychiatry and Behavioral Sciences at Stanford University

He is a former student of the Ecole Normale Superieure (Ulm, Paris, France) and received his M.D. and Ph.D. from Paris V and VI University in France. He practiced medicine in France for several years before joining Stanford as a faculty member in 1991 and was named Director of the Stanford Center for Narcolepsy in 1993. Dr. Mignot was named the Craig Reynolds Professor of Psychiatry and Behavioral Sciences in 2001. He served as the Director of the Stanford Center of Sleep Sciences and Medicine from 2009 to 2019.

Dr. Mignot is internationally recognized for discovering the cause of narcolepsy. His findings led to the development of new hypnotics that block the hypocretin (orexin) receptor and is likely to have other therapeutic applications as well. His research also demonstrated that narcolepsy is a selective autoimmune disease of the hypocretin system showing the involvement of molecular mimicry in humans with influenza A.

He has received numerous research grants and honors including National Sleep Foundation and National Institute of Health Research Awards, Howard Hughes Medical Institute Investigator and McKnight Neuroscience awards, the Narcolepsy Network professional service award, the Drs. C. and F. Demuth 11th Award for Young Investigators in the Neurosciences, the WC Dement Academic Achievement Award in sleep disorders medicine, the CINP and ACNP awards in neuropharmacology and the Jacobaeus prize.

Dr. Mignot is an elected member of the Association of American Physicians, the Institute of Medicine, and of the National Academy of Sciences (USA). He is the co-author of more than 200 original scientific publications, and he serves on the editorial board of scientific journals in the field of sleep and biology research. Dr. Mignot is an active member of several professional and governmental organizations. He has served as President of the Sleep Research Society, Chair of the National Center on Sleep Disorders Research Advisory board of the National institutes of Health, and Chair of the Board of Scientific Counselors of the National Institute of Mental Health.

Most of Dr. Mignot's current research focuses on the neurobiology, genetics and immunology of narcolepsy, a disorder caused by hypocretin (orexin) cell loss, with indirect interest in the neuroimmunology of other brain disorders. His laboratory uses state of the art human genetics techniques, such as genome wide association, exome or whole genome sequencing in the study of human sleep and sleep disorders, with parallel studies in animal models. His laboratory is also interested in web-based assessments of sleep disorders, computer-based processing of polysomnography (PSG), and outcomes research. Dr. Mignot serves as a consultant to Idorsia.

References

About IdorsiaIdorsia Ltd is reaching out for more - We have more ideas, we see more opportunities and we want to help more patients. In order to achieve this, we will develop Idorsia into one of Europes leading biopharmaceutical companies, with a strong scientific core.

Headquartered in Switzerland - a biotech-hub of Europe - Idorsia is specialized in the discovery and development of small molecules, to transform the horizon of therapeutic options. Idorsia has a broad portfolio of innovative drugs in the pipeline, an experienced team, a fully-functional research center, and a strong balance sheet the ideal constellation to bringing R&D efforts to business success.

Idorsia was listed on the SIX Swiss Exchange (ticker symbol: IDIA) in June 2017 and has over 800 highly qualified specialists dedicated to realizing our ambitious targets.

For further information, please contactAndrew C. WeissSenior Vice President, Head of Investor Relations & Corporate CommunicationsIdorsia Pharmaceuticals Ltd, Hegenheimermattweg 91, CH-4123 Allschwil+41 58 844 10 10www.idorsia.com

The above information contains certain "forward-looking statements", relating to the company's business, which can be identified by the use of forward-looking terminology such as "estimates", "believes", "expects", "may", "are expected to", "will", "will continue", "should", "would be", "seeks", "pending" or "anticipates" or similar expressions, or by discussions of strategy, plans or intentions. Such statements include descriptions of the company's investment and research and development programs and anticipated expenditures in connection therewith, descriptions of new products expected to be introduced by the company and anticipated customer demand for such products and products in the company's existing portfolio. Such statements reflect the current views of the company with respect to future events and are subject to certain risks, uncertainties and assumptions. Many factors could cause the actual results, performance or achievements of the company to be materially different from any future results, performances or achievements that may be expressed or implied by such forward-looking statements. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those described herein as anticipated, believed, estimated or expected.

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Idorsia announces positive results in the second Phase 3 study of daridorexant - GlobeNewswire

Who Pioneered Robotics? – ThoughtCo

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We have evidence that mechanized human-like figures date back to ancient times to Greece. The concept of an artificial man is found in works of fiction since the early 19th century. Despite theseinitial thoughts and representations, thedawn of the robotic revolution began in earnest in the 1950s.

George Devol invented the first digitally operated and programmable robotin 1954. This ultimately laid the foundation of the modern robotics industry.

Around 270 B.C. an ancient Greek engineer named Ctesibius made water clocks with automatons or loose figures. Greek mathematicianArchytasof Tarentum postulated a mechanical bird he called "The Pigeon" which was propelled bysteam. Hero of Alexandria (1070 AD)made numerous innovations in the field of automata, including one that allegedly could speak.

Inancient China, an account about an automaton is found in the text, written in the 3rd century BC, in whichKing Mu of Zhouis presented with a life-size, human-shaped mechanical figure by Yan Shi, an "artificer."

Writers and visionaries envisioned a worldincluding robotsin daily life. In 1818, Mary Shelley wrote "Frankenstein," which was about a frightening artificial lifeform come to life by a mad, but brilliant scientist, Dr. Frankenstein.

Then, 100 years later Czech writer Karel Capek coined the term robot, in his 1921 play called "R.U.R." or "Rossum's Universal Robots." The plot was simple and terrifying; the man makes a robot then robot kills a man.

In 1927,Fritz Lang's "Metropolis"was released. TheMaschinenmensch("machine-human"), ahumanoid robot, was the first robot ever to be depicted on film.

Science fiction writer and futurist Isaac Asimov first used the word "robotics" in 1941 to describe the technology of robots and predicted the rise of a powerful robot industry. Asimov wrote "Runaround," a story about robots which contained the "Three Laws of Robotics," which centered around Artificial Intelligence ethics questions.

Norbert Wiener published "Cybernetics," in 1948, which formed the basis of practical robotics, the principles of cybernetics based on artificial intelligence research.

British robotics pioneer William Grey Walter invented robots Elmer and Elsie that mimic lifelike behavior using elementary electronics in 1948. They were tortoise-like robots that were programmed to find their charging stations once they started running low on power.

In 1954 George Devol invented the first digitally operated and a programmable robot called theUnimate. In 1956, Devol and his partner Joseph Engelberger formed the world's first robot company. In 1961, the first industrial robot, Unimate, went online in a General Motors automobile factory in New Jersey.

With the rise of the computer industry, the technology of computers and robotics came together to form artificial intelligence; robots that could learn. The timeline of those developments follows:

Commercial and industrial robots are now in widespread use performing jobs more cheaply or with greater accuracy and reliability than humans. Robots are used for jobs which are too dirty, dangerous or dull to be suitable for humans.

Robots are widely used in manufacturing, assembly and packing, transport, earth and space exploration, surgery, weaponry, laboratory research and mass production of consumer and industrial goods.

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Who Pioneered Robotics? - ThoughtCo

The Best Robotics Colleges | Successful Student

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The thriving robotics field, growing by leaps and bounds, has inspired many colleges and universities to provide high quality robotics programs. Students have numerous robotics engineering colleges from which to choose. Some schools offer a robotics engineering degree or a type of robotics degree, however many schools offer robotics-related undergraduate and graduate degree programs in mechanical engineering, electrical engineering or computer programming.

Robotics serves as the science and technology for the design, manufacturing and application of robots. Robotics, an interdisciplinary field, includes the fields of mechanical engineering, electrical engineering and computer programming.

Robotics professionals develop and apply robotic solutions to a wide range of industrial and consumer issues.

Robotics collaborates artificial intelligence with robots to allow robots to react and respond to their surroundings in real time, without guidance other than computer programming. Companies use robots in arenas, dangerous for humans (such as defusing bombs), however companies increasingly use robots in fields to fill labor roles in manufacturing, complete tasks in healthcare, and serve as receptionists, guides, and helpers. Robots are also utilized for domestic or household use.

A robot is a programmable mechanical device with the ability to perform tasks and interact with its environment, without the aid of human interaction. Robots can sense, compute, and act. Some robots can move around; some robots can manipulate things; whereas some robots can move around and manipulate things. Robotics engineers design some robots to perform specific tasks, whereas some robots can perform many different tasks.

Robotics Colleges Ranking Guidelines

Robotics Career and Job Growth Information

Carnegie Mellon University, a private research university, averages a 13-14% acceptance rate. The university is the fourth largest in Pittsburgh based on number of students.

The school, Andrew Carnegie founded in 1900, has grown to include these colleges: Engineering, Fine Arts, Dietrich College of Humanities and Social Sciences, Mellon College of Science, Tepper School of Business, H. John Heinz III College of Information Systems and Public Policy and the School of Computer Science.

US News and World Report ranks Carnegie Mellon University #25 in the United States, and #81 in the world. The School is the best robotics college in the nation.

Carnegie Mellon, entrenched in the world of robotics since 1979 when they opened the Robotics Institute, offers robotics related degree options as an additional major, a minor, a bachelor of science, a master of science, or a PhD program.

Robotics Masters Research Program: Students complete a compilation of course requirements, electives, and supervised research. Students complete a public thesis talk and a Masters thesis document as the capstones of the program.

Graduates of the program can seek a career in the research field with companies such as NASA or Google, or they can continue their studies to a doctorate program. During the program, students gain a broad-level understanding of the robotics field, but they also select a specialization area. Some of the possible selections include Haptics, Human-Robot Interactions, and Machine Learning.

The core learning a student participates in comes from the following divisions: Perception, Cognition, Action, and Math Foundations.

Students can complete the entire program in 24 months.

Robotics degrees: Additional Major in Robotics, Undergraduate Minor in Robotics, PhD and Master of Science in Robotics

Massachusetts Institute of Technology (MIT) founded in 1861, is a private research university. The school mascot, Tim the Beaver, represents the over 11,000 students who managed to be a part of the 7-8% of accepted applicants.

The School has always emphasized the importance of early laboratory introduction; researchers began working on computers, radar and inertial guidance during World War II and the Cold War.

US News and World Report ranks MIT 7th in the United States and 2nd globally.

While MIT does not offer a specific robotics major, the School offers students a couple of paths to specialize in the field. Students may choose to select Course 2, Mechanical Engineering, as their major. Within this major there are two courses which offer students exposure to the study of Robotics:the Design of Electromechanical Robotic Systems course and the Design and Manufacturing I course which also allows participation in a robotics contest.

Additionally, MIT offers some freshman seminars regarding robotics for example, one within Course 6 (EECS) titled Mens at Manus: Building on the Science Core. Students may also select EECS as their major then choose one of three paths: Electrical Science and Engineering, Computer Science and Engineering, or Electrical Engineering and Computer Science. Within Course 6, students have many courses around robotics to choose from.

MIT also recognizes a number of Robotics Groups: Perceptual Science Group, DArbeloff Lab: Robotics, and Personal Robotics Group among them.

Robotics degree: Master of Science in Computer Science: Intelligent Robotics

Established in 1740, the University of Pennsylvania, or Penn, is the fourth oldest university in the United States, and the first to offer both graduate and undergraduate studies. The school was one of only nine universities to receive a charter before the American Revolution.

Penn was founded by Benjamin Franklin, and the universitys coat of arms, consisting of a dolphin on the red chief, is modeled after that of the Franklin family.

The University is third behind Harvard and Stanford when it comes to the production of CEO of Fortune 500 companies. Through its rich history, Penn has grown to accommodate a student body of over 21,000.

The University of Pennsylvania offers a General Robotics, Automation, Sensing and Perception (GRASP) laboratory within the School of Engineering and Applied Science. The group was an early adopter of the idea of robotics, getting its start in 1979. Ms. Ruzena Bajcsy, who is now considered a pioneer in the field and still active in the arena, founded the research lab.

Penn claims being a pioneer in the concept of interdisciplinary research in robotics and the strong foundation has only grown now including faculty from Electrical and Systems Engineering, Computer and Information Science, Mechanical Engineering and Applied Mechanics and the medical school.

Robotics degrees: Master of Science in Robotics and Doctorate on Philosophy focusing on robotics (through either the Computer and Information Science, Electrical and Systems Engineering, or Mechanical Engineering and Applied Mechanics departments within Penn Engineering)

The University of Michigan, a public university established in 1817, has nearly 45,000 students and boasts over 540,000 living alumni. The campus includes nearly 600 major buildings (including the Central Campus, North Campus, two regional campuses and a center in Detroit).

In establishing the University of Michigan Robotics Institute, the university seeks to integrate all disciplines studying robotics to foster collaboration and accelerate robotics research. While this research will take place across campuses, at collaborating universities, at research sites around the world, and even in space, the hub of Michigan Robotics where the next generation of roboticists train will beunder one roof in a new state-of-the-art $75 million facility scheduled for completion in 2020. The University designed the space to serve as collaborative labs and classrooms, with an indoor flight lab for flying autonomous vehicles, an outdoor playground for testing robots, and a partnership with Ford Motor Company, whose employees will share the building with students and faculty.

The University of Michigan Robotics Institute offers both a Masters and a PhD option that look to build robotics applications through the integration of knowledge from across various fields of study.

Michigan Robotics focuses on three main essential disciplines: Sensing the environment, reasoning to make decisions, and acting to produce motion or other outputs. Specific focus areas include: legged locomotion; human-robot interaction; autonomous vehicles; manipulation; cooperative robots; manufacturing; mobile, perception and rehabilitation robots.

Robotics degrees: Master of Science or Doctorate in Robotics

The Georgia Institute of Technology, a public university founded in 1885 and commonly referred to as Georgia Tech, has grown to accommodate a student body of nearly 30,000 individuals.

The university has six colleges, but still has an emphasis on sciences and technology and is well-known for engineering, computing, business administration, sciences, design and liberal arts programs. US News and World Report ranks Georgia Tech 7th among American public universities, 34th of all universities in the United States and 71st globally.

Georgia Tech manages the Institute for Robotics and Intelligent Machines. The Institute serves as an umbrella to cover individuals studying any and all disciplines and who have an interest in robotics. Through the joint venture, the Institute achieves new strengths as inter-disciplinary individuals come together and solve problems with maximum collaboration and creativity.

Georgia Tech offers a robotics degree, a PhD in Robotics, which serves many disciplines, and an undergraduate summer program for underrepresented minorities. The School also has a traineeship program involving healthcare robotics.

Robotics degrees: Master of Science and PhD in Robotics

Stanford University has a total enrollment of over 16,000 students. Leland and Jane Stanford established the University in 1885 in memory of Leland Stanford Junior, their only child. Their son passed away in 1884 of typhoid fever at age 15. Leland Senior served as a California governor and made his fortune through the railroad.

Stanford alumni and faculty have experienced success as entrepreneurs the nearly 40,000 companies they have founded since the 1930s produce nearly $3 trillion in annual revenue, and have created nearly 5.5 million jobs. If those stats were combined into an independent nation and ranked among economies, it would have the 10th largest economy in the world. Some of the companies: Instagram, Nike, Cisco Systems, Capital One, Hewlett-Packard, Netflix and Trader Joes.

Among the graduate studies at Stanford, students interested in robotics can explore the School of Engineeringgraduate program, specializing their research in robotics through either Mechanical Engineering or Computer Science through the Artificial Intelligence research area.

Research facilities include the Stanford Robotics Lab and the Stanford Artificial Intelligence Lab. Members of the Artificial Intelligence research group have contributed to fields such as computer vision, knowledge systems, decision theory, and bio-information.

Some robotic creations and advancements attributed to Stanford include the Sanford Arm, the Stickybot, OceanOne, flapping robots, Vinebot, and Jack Rabbot.

Robotics programs: Robotics minor, Master of Science through Laboratory for Computational Sensing and Robotics

Harvard University provides undergraduate programs in Applied Mathematics, Bioengineering, Computer Science, Electrical Engineering, Environmental Science and Engineering, and Mechanical Engineering.

Graduate students focus on one of seven areas during their studies: Applied Mathematics, Applied Physics, Computer Science, Computational Science & Engineering, Data Science, Design Engineering, or Engineering Sciences.

Students and faculty have resources and research opportunities through facilities such as:

Additional research areas include robotic assistance in physical therapy, rescue robots that can respond to natural or man-made disasters, bio-inspired robotics, the automation of manufacturing and shipping with robotic technology, and more.

Robotics related degrees: BS or MS in Electrical and Systems Engineering, BS or MS in Computer and Information Science, BS or MS in Mechanical Engineering

The Fu Foundation School of Engineering and Applied Science manages nine academic departments: Applied Physics and Applied Math, Biomedical Engineering, Chemical Engineering, Civil Engineering and Engineering Mechanics, Computer Science, Earth and Environmental Engineering, Electrical Engineering, Industrial Engineering and Operations Research, and Mechanical Engineering. Each of these departments offers a variety of bachelor, master, and doctoral level degrees relating to robotics in their own unique ways.

In Civil Engineering and Engineering Mechanics, for example, students can study self-driving vehicles, can research and improve the effectiveness of green roofing, and can understand the use of sensors to help maintain bridge safety. Students in the Mechanical Engineering department deal most directly with human-robot interactions such as improving laser robotic surgery.

Students interested in further research and networking in the field of robotics can connect with the Columbia University Robotics Group. The Group has several on-going research areas including: Multimodal Brain Computer Interface for Human-Robot Interaction, Surgical Tool Tracking, Dexterous Manipulation Using Predictive Thin-Shell Modeling, Protein Streak Seeding, and Visual Servoing: A Partitioned Visual Feedback System.

Robotics related degrees: BS or MS in Mechanical Engineering, BS or MS in Electrical Engineering

Cornell University is a private, land-grant, sea-grant, space-grant and research institution. Ezra Cornell and Andrew Dickson White established the University in 1865 with the desire to educate and contribute to all fields of knowledge.

Cornell University has over 21,000 students across its campuses including the main Ithaca campus, two satellite medical campuses (one in New York City and one in Education City, Qatar), and Cornell Tech, which has a campus on Roosevelt Island. The student body represents over 120 countries.

The University does not have a specific robotics program for undergraduate students, but between the Engineering and Computer Science departments, the University covers a substantial amount of Robotics material.

Students studying robotics at Cornell University can learn about various facets of Robotics including perception, learning, control, and human-robot interaction. The team utilizes several robots for research and learning purposes: aerial robots, humanoids, office and home assistant robots, and autonomous cars, among others.

Some of the background courses helpful in the Robotics field offered at the University include Intro to Computer Science using Robots, Intellectual Physical Systems and Foundations of Robots. Some of the intermediate and advanced courses include Autonomous Mobile Robots, Human-Robot Interaction, Foundations of Robotics, Computer Vision, and Machine Learning for Intelligent Systems.

Robotics Degree: PhD in Robotics, Undergraduate Summer Program, Traineeship Program involving Healthcare Robotics

Johns Hopkins University, named after abolitionist, entrepreneur and philanthropist Johns Hopkins, was founded in Baltimore, Maryland in 1876. Hopkins was the first benefactor for the university, his gift the largest in the history of America at the time went partially to the university and partially to fund Johns Hopkins Hospital.

Hopkins University followed the example set by Heidelberg University in Germany to begin their graduate studies program, and hence earned the title of the first research university in the United States. The private university calls Baltimore home, but the School also has divisions on campuses in Washington, DC, Italy, Singapore and China, allowing the school to reach over 20,000 students.

Hopkins University offers robotics as either a minor or a Masters degree through their Laboratory for Computational Sensing and Robotics (LCSR). Both programs encompass areas of study such as mechanics, dynamics, kinematics, signal processing, planning, artificial intelligence, control systems, and signal processing.

The laboratory operates through the Hopkins Whiting School of Engineering, but the minor is not actually owned by any one college. Students receive credit for their studies in the Robotics field on a transcript, instead of just through specialized classes. This fosters students from various disciplines to participate in the Robotics arena.

The minor consists of earning six to 12 credit hours from three core areas: robot kinematics and dynamics; systems theory, signal processing and control; and computation and sensing.

The Masters degree has two options either a course work option, which requires 10 full-time courses, or an essay option, which requires eight full-time courses and a masters essay. Students in the masters program can select a specialized track from the following: automation science and engineering, bio-robotics, control and dynamical systems, perceptive and cognitive systems, general robotics, and medical robotics and computer integrated surgical systems.

Robotics related degrees: BS or MS in Mechanical Engineering, BS or MS in Computer Science

Founded in 1880, the University of Southern California is Californias oldest private research university. USC contributes $8 billion each year to the economy of LA and California. USC boasts over 42,000 students and nearly 4,000 member staff.

USC houses the Robotics and Autonomous Systems Center (RASC), founded in 2002. The RASC serves as an organized research unit intended for multi-discipline use within the College of Engineering. The lab members focus their research on the far-reaching field of technology of robotics systems. The research impacts areas at USC such as humanoid, reconfigurable, and nano and space robotics, and applications such as training, rehabilitation, emergency response and entertainment.

Within the department of Computer Science, USC offers a Master of Science in Computer Science (Intelligent Robotics). The graduate-level degree exposes students to the design and construction of robots, and to the computer systems required for control and information processing.

While earning their Intelligent Robotics degree, students complete courses such as Analysis of Algorithms, Robotics, Self-Organization, Machine Learning and Probabilistic Learning. The school is one of the best robotics colleges in the nation.

Robotics related degrees: BS or MS in Electrical Engineering, BS or MS in Computer Science

The School of Engineering dedicates time and energy to innovative research which includes robotics and other forms of artificial intelligence.

UCLA has several research facilities for the study of robotics and their various aspects including the following:

UCLA also has a team of researchers developing soccer robots.

Robotics related degrees: BS or MS in Engineering, BS or MS in Computer Science

The University of California, Berkeley also known as UC Berkeley or Cal was founded in 1868. In 2019, US News and World Report ranked UC Berkeley the #2 public school. The University has over 41,000 students.

Berkeley is heavily involved in various research capacities.

Students interested in robotics can participate in the Berkeley Robotics and Intelligent Machines Lab. The Lab manages several research groups including:

The Biomimetic Millisystems Lab which seeks to harness features of animal manipulation, sensing and actuation to improve millirobot functionality.

The People and Robots group emphasizes societys interaction with robots focusing on areas such as Bio-Inspired robotics, Deep Learning, and Cloud Robotics.

The Robot Learning group researches new and interesting methods for machine learning, perception and control.

Other group options and research areas include theBerkeley Laboratory for Automation Science and Engineering, The BErkeley AeRobot (BEAR) project, the Computer Vision group, Medical Robots, and more.

Robotics related degrees: BS or MS in Electrical Engineering, BS or MS in Computer Science

The University of Washington, founded in 1861, located in downtown Seattle, Washington, also has campuses in Tacoma and Bothell. Overall, the University includes over 20 million square feet of space, and over 500 buildings. The university also has over 26 libraries, making it one of the largest university library systems in the world.

The school has over 46,000 students and nearly 6,000 academic staff members.

The Paul G. Allen School of Computer Science and Engineering offers multidisciplinary study of robotics covering a variety of study areas includingmechanism design, Bayesian state estimation, biomechanics, neural control of movement, robot learning, and natural language instruction.

The robotics research areas includes labs such as:

Some courses at University of Washington, applicable to robotics at the undergrad level include the robotics capstone and capstone software Kinect.

Other affiliated research centers include the Institute for Learning and Brain Science, the Center for Sensorimotor Neural Engineering, the Center for Game Science, and the Intel Science and Technology Center for Pervasive Computing.

Robotics related degrees: BS or MS Computer Science

The University provides over 20 undergraduate and graduate level degree programs, the majority of which allow students to study robotics. These include the undergraduate majors of Aerospace Engineering, Computer Engineering, Electrical Engineering, and Mechanical Engineering. Students can study the same undergraduate areas at the Masters or Doctoral levels.

The School of Engineering manages several facilities of research including the Institute for Systems Research, which houses the Maryland Robotics Center. This interdisciplinary research facility studies all aspects of robotics including intelligence, component technologies, and system autonomy.

The School of Engineering maintains the Space Systems Laboratory and the Neutral Buoyancy Research Facility. These facilities specialize in astronautics and the simulation of microgravity environments. The University of Maryland has a unique neutral buoyancy tank.

Robotics related degrees: BS or MS in Computer Science, BS or MS in Engineering

Oregon State University (OSU), founded in 1868, is one of only three American institutions designated as a land-grant, sea-grant, space-grant and sun-grant university. It is one of only two public universities with all four designations, along with Penn State. OSU enrolls over 30,000 students, including over 25,000 undergraduates.

Oregon State University has adopted the position robots are here to stay, thus the educational system must adapt to create the next generation of researchers and innovators. OSU recognizes robotics touch numerous fields business, engineering, communication, transportation, agriculture, national defense, and medicine. OSU is one of the few institutes of higher education to offer graduate studies in Robotics.

Working to develop and harness the potential of robotics in todays world led to the formation of the Collaborative Robotics and Intelligent Systems Institute (CoRIS) at OSU.

OSU faculty members consider their position unique; they approach the idea of robotics holistically studying technological advancement, while considering how the robots impact people and how the changes brought by the widespread use of robots will shape our society.

Faculty members involved in robotics explore the technical, ethical, social, and economic implications innovations will bring.

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The Best Robotics Colleges | Successful Student

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Robotics | Johns Hopkins Whiting School of Engineering

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A research team at Johns Hopkins has developed a prototype robot with movements inspired by those of a Central American cockroach species. (Image: Will Kirk / Homewood Photography)

The Laboratory for Computational Sensing and Robotics (LCSR) was founded by the Whiting School of Engineering as the principal locus for robotics research at one of the worlds premier research universities. Its mission is to create knowledge and foster innovation to further the field of robotics science and engineering by cultivating excellence in research and teaching in robotics engineering sciences, and by utilizing opportunities for robotics research and collaboration across all Johns Hopkins University divisions and with collaborators worldwide. Located in Hackerman Hall on the Homewood campus, the LCSR is one of the largest and most technologically advanced robotics centers in the world. It comprises personnel from across all of Johns Hopkins University, and fosters targeted research programs and collaboration with universities, corporations, and other research organizations worldwide. Our undergraduate robotics minor and masters degree in robotics provide a structure in which students from a wide variety of engineering, scientific, and mathematical backgrounds can advance their interdisciplinary knowledge in robotics.

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Robotics | Johns Hopkins Whiting School of Engineering

Laboratory Robotics and Automation Market Gets Significant Impetus During Covid-19 Outbreak; Demand to Sustain Post Pandemic – Cole of Duty

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A fresh specialized intelligence report published by KandJ Market Research with the title Global Laboratory Robotics and Automation Market Research Report By Types, Applications and Regions, Countries and Forecast to 2026 has the ability to help the decision-makers in the most important market in the world that has played a significantly important role in making a progressive impact on the global economy.

Market Overview

The global Laboratory Robotics and Automation markethas been comprehensively analyzed in the report and presents the scope of growth of the market that can be expected during both the base period from the year 2016 to the year 2020 and for the forecast period from the year 2020 to the year 2026. The market overview of the Laboratory Robotics and Automation industry is also included in the report. The trends that are expected to be successful during the forecast period due to the growth of the Laboratory Robotics and Automation market are identified and are presented in detail. The Laboratory Robotics and Automation market report is a valuable source of guidance.

Market Dynamics

The global Laboratory Robotics and Automation market growth can be either boosted or declined based on different factors. These factors are analyzed in detail to predict the effect that they can have on the global Laboratory Robotics and Automation market and are categorized as such. These factors also play a major role in deciding the direction that the Laboratory Robotics and Automation market can take. The market growth rate from the year 2016 to the year 2020 has been presented based on the volume of products sold and the value of each unit produced. The data has been forecast from the year 2020 to the year 2026.

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Segmental Analysis

The global Laboratory Robotics and Automation market is divided into different market segments according to different parameters.This smaller segmentation enables greater control and accuracy over the data collected. The report segments that market into smaller regions based on locations around the world. These different regions include Asia-pacific, North America, South America, the Middle East, Africa, and Europe. This segmentation also presents the market share occupied by each of these regions and categorizes them based on the ones that have the largest global market share. The scope of growth of these different regions is also presented in the report for the forecast period from the year 2020 to the year 2026.

Market Analysis by Type

Market Analysis by Applications

Market Analysis by Regions

Research Methodology

The data used to compile the Laboratory Robotics and Automation market report has been collected from different primary and secondary sources. This data has to then be analyzed to verify the accuracy while also being error-free. The data is analyzed according to different parameters, one of which is the SWOT analysis. The data is analyzed to identify the strengths and weaknesses of different companies along with the opportunities that can be exploited and the threats that they face from different directions and opponents.

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The global Laboratory Robotics and Automation market report identifies different companies that occupy a large market share in the Laboratory Robotics and Automation market. These companies are then subjected to a comprehensive analysis to identify different parameters that have contributed to the growth of the market. The popular trends that these companies use to increase the market share that they occupy are also identified. The different advancements in manufacturing technology that has enabled them to gain an edge over other competitors are also listed. The data related to each of the companies has been presented from the year 2016 to the year 2020 and is predicted for the forecast period from the year 2020 to the year 2026.

Market Analysis by Key Players

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Laboratory Robotics and Automation Market Gets Significant Impetus During Covid-19 Outbreak; Demand to Sustain Post Pandemic - Cole of Duty

Inspection Robotics in Oil and Gas Market Insights, Trends, Analysis, Types, Applications, key players, Market shares and Forecast 2019 to 2023 – Cole…

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In 2019, the market size of Inspection Robotics in Oil and Gas Market is million US$ and it will reach million US$ in 2025, growing at a CAGR of from 2019; while in China, the market size is valued at xx million US$ and will increase to xx million US$ in 2025, with a CAGR of xx% during forecast period.

In this report, 2019 has been considered as the base year and 2019 to 2025 as the forecast period to estimate the market size for Inspection Robotics in Oil and Gas .

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This study presents the Inspection Robotics in Oil and Gas Market production, revenue, market share and growth rate for each key company, and also covers the breakdown data (production, consumption, revenue and market share) by regions, type and applications. Inspection Robotics in Oil and Gas history breakdown data from 2014 to 2019, and forecast to 2025.

For top companies in United States, European Union and China, this report investigates and analyzes the production, value, price, market share and growth rate for the top manufacturers, key data from 2014 to 2019.

Segment by Type, the Inspection Robotics in Oil and Gas market is segmented intoROVsAUVsUAVsUGVs

Segment by Application, the Inspection Robotics in Oil and Gas market is segmented intoOil and Gas PipelinesPlatformsRigsOil Storage TankOther Oil and Gas Structures

Regional and Country-level AnalysisThe Inspection Robotics in Oil and Gas market is analysed and market size information is provided by regions (countries).The key regions covered in the Inspection Robotics in Oil and Gas market report are North America, Europe, China and Japan. It also covers key regions (countries), viz, the U.S., Canada, Germany, France, U.K., Italy, Russia, China, Japan, South Korea, India, Australia, Taiwan, Indonesia, Thailand, Malaysia, Philippines, Vietnam, Mexico, Brazil, Turkey, Saudi Arabia, U.A.E, etc.The report includes country-wise and region-wise market size for the period 2015-2026. It also includes market size and forecast by Type, and by Application segment in terms of production capacity, price and revenue for the period 2015-2026.Competitive Landscape and Inspection Robotics in Oil and Gas Market Share Analysis

Inspection Robotics in Oil and Gas market competitive landscape provides details and data information by manufacturers. The report offers comprehensive analysis and accurate statistics on production capacity, price, revenue of Inspection Robotics in Oil and Gas by the player for the period 2015-2020. It also offers detailed analysis supported by reliable statistics on production, revenue (global and regional level) by players for the period 2015-2020. Details included are company description, major business, company total revenue, and the production capacity, price, revenue generated in Inspection Robotics in Oil and Gas business, the date to enter into the Inspection Robotics in Oil and Gas market, Inspection Robotics in Oil and Gas product introduction, recent developments, etc.The major vendors covered:GE Inspection RoboticsECA GroupInternational Submarine Engineering LtdInuktun Services LtdFlyability SAIKM Subsea ASING Robotic AviationMISTRAS Group Inc.Helix ESG

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The content of the study subjects, includes a total of 15 chapters:

Chapter 1, to describe Inspection Robotics in Oil and Gas product scope, market overview, market opportunities, market driving force and market risks.

Chapter 2, to profile the top manufacturers of Inspection Robotics in Oil and Gas , with price, sales, revenue and global market share of Inspection Robotics in Oil and Gas in 2017 and 2019.

Chapter 3, the Inspection Robotics in Oil and Gas competitive situation, sales, revenue and global market share of top manufacturers are analyzed emphatically by landscape contrast.

Chapter 4, the Inspection Robotics in Oil and Gas breakdown data are shown at the regional level, to show the sales, revenue and growth by regions, from 2014 to 2019.

Chapter 5, 6, 7, 8 and 9, to break the sales data at the country level, with sales, revenue and market share for key countries in the world, from 2014 to 2019.

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Chapter 10 and 11, to segment the sales by type and application, with sales market share and growth rate by type, application, from 2014 to 2019.

Chapter 12, Inspection Robotics in Oil and Gas market forecast, by regions, type and application, with sales and revenue, from 2019 to 2024.

Chapter 13, 14 and 15, to describe Inspection Robotics in Oil and Gas sales channel, distributors, customers, research findings and conclusion, appendix and data source.

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Inspection Robotics in Oil and Gas Market Insights, Trends, Analysis, Types, Applications, key players, Market shares and Forecast 2019 to 2023 - Cole...

Expanding Scope on Robotics lawn mower Market 2020 COVID-19 Impact, Share, Trend, Segmentation and Forecast to 2025 |Husqvarna Group , Deere and…

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This research will help both established and new entrants to identify and analyze market needs, market size and competition. It explains the supply and demand situation, the competitive scenario, and the challenges for market growth, market opportunities and the threats faced by key players.

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A detailed outline of the Global Robotics lawn mower Market includes a comprehensive analysis of different verticals of businesses. North America, Latin America, Asia-Pacific, Africa, and Europe have been considered for the studies on the basis of several terminologies.

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Expanding Scope on Robotics lawn mower Market 2020 COVID-19 Impact, Share, Trend, Segmentation and Forecast to 2025 |Husqvarna Group , Deere and...

The COVID-19 Stress: 5 Ways To Cope And Protect Your Health – India New England

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The millions of infections and hundreds of thousands of deaths that the COVID-19 pandemic has brought globally are creating stress over everything from personal health to employment, lifestyle, and finances.

Given these difficult circumstances, its more important than ever for people to know about coping mechanisms to better manage stress, protect their immune system, and increase their chances of staying healthy, says Dr. Nammy Patel,DDS (www.sfgreendentist.com), author ofAge With Style: Your Guide To A Youthful Smile & Healthy Living.

COVID is maximizing stress for so many people, Dr. Patel says. It has a far-reaching impact into every part of our lives, and if we dont manage the stress, it severely affects our bodily systems causing burned-out adrenals, high cortisol, and thyroid issues, to name a few consequences of high-stress levels. Thus, the immune system is lowered, and we are more vulnerable to illness.

This era we are living in is very traumatic, and its very concerning. In dentistry, gum disease, sleep disturbances or apnea, and teeth breakage can all be evidence of stress. Poor oral health, as studies show, can be a gateway to medical issues. People often dont identify how much stress theyre under, and how its affecting them physically, until they actually get sick.

Dr. Patel has the following suggestions people can incorporate into their daily lives to better deal with stress:

The disruption of daily life by COVID-19 has caused us to rethink many things that we do, Dr. Patel says. How we deal with stress needs to be a priority now, and its not overly difficult if you develop good daily habits.

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The COVID-19 Stress: 5 Ways To Cope And Protect Your Health - India New England

What Is Dental Anxiety? Here Are Some Tips To Deal With It – NDTV Doctor

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Oral Health: Dental anxiety can make it difficult to undergo dental procedures. It develops a fear in an individual. Read here to know more about dental anxiety.

Do not skip flossing to prevent dental issues

One should follow healthy dental practices other than just brushing twice a day. It is often advised to visit your dentist to prevent the risk of dental issues. Many are not aware of dental issues and often choose to ignore minor dental discomforts. Dental issues are quite painful. Some also fear visiting a dentist due to dental anxiety. It is a term used to describe fear, anxiety and stress in a dental sitting. It is also called dental phobia which can make you avoid going to the dentist and you usually cannot do anything about it.

Dr. Gunita Singh who is a dentist explains, "Dental anxiety is a term used to describe certain anxiety or fear associated with visiting a dentist. People with this fear usually are scared of a dentist and dental set up. The severity may vary from person to person. This is generally due to some past experience of the individual or their loved ones."

Pay regular visits to your dentist to prevent major dental issuesPhoto Credit: iStock

1. It is important to learn the need to pay regular visits to your dentist to ward off potential risks. It is essential for adults as well as children. Don't scare your children with the name of a doctor

2. You need to trust your dentist to fight with this anxiety. You may also ask your dentist about the whole procedure to understand it better.

3. You should also prepare yourself mentally before going througha dental procedure

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(Dr. Gunita Singh is a Dentist and Director at Dentem)

Disclaimer: This content including advice provides generic information only. It is in no way a substitute for qualified medical opinion. Always consult a specialist or your own doctor for more information. NDTV does not claim responsibility for this information.

DoctorNDTV is the one stop site for all your health needs providing the most credible health information, health news and tips with expert advice on healthy living, diet plans, informative videos etc. You can get the most relevant and accurate info you need about health problems like diabetes, cancer, pregnancy, HIV and AIDS, weight loss and many other lifestyle diseases. We have a panel of over 350 experts who help us develop content by giving their valuable inputs and bringing to us the latest in the world of healthcare.

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What Is Dental Anxiety? Here Are Some Tips To Deal With It - NDTV Doctor