Researchers develop credit-card sized tool to understand how cancer cells invade host tissues – News@UofT

A group of researchers from the University of Toronto hasdeveloped a credit-card sized tool for growing cancer cells outside the human body, which they believe will enhance their understanding of breast cancer metastasis.

The device, described in a paperpublished on July 15inScience Advances, reproduces various environments within the human body where breast cancer cells live. Studying the cells as they go through the process of invasion and metastasis could point the way toward new biomarkers and drugs to diagnose and treat cancer.

Metastasis is what makes cancer so deadly, said the publication's corresponding authorAaron Wheeler, a professor in the Institute of Biomedical Engineering in the Faculty of Applied Science & Engineering, whose lab is located in theDonnelly Centre for Cellular and Biomolecular Researchin U of T's Faculty of Medicine.

If cancer cells would simply stay in one spot, it would be easy to excise them and cure the disease. But when cancer metastasizes, cancer cells move through the body, making the disease difficult to treat.

We decided to apply our expertise in microfluidics to develop a new tool to aid in studying how cancer cells begin to invade into surrounding tissues in the first steps in metastasis.

Normally metastasis is studied in a petri dish cell culture or in whole animals. However, these model systems present problems in terms of cost, efficiency, or lack of representation.

An oversimplified system like cells in petri dishes doesnt mimic what happens in the body, while in an animal model, its difficult to isolate and study parameters that govern the invasiveness of a cell, saidBetty Li, a senior Institute of Biomedical Engineering PhD student and leadauthor of the paper.

Our system gives us control over all the specific parameters that we want to look at, while allowing us to make structures that better resemble what happens to the body.

The device consists of patterned metal electrodes which can move extremely small droplets around through the use of electric fields. By selectively changing the water-repelling properties of the surface at various points, researchers can pinch off the water droplets and form precise shapes.

In the paper, the researchers describe how they used a collagen matrix coated with a layer of basal membrane extract to mimic the structure of the breast tissue seen by breast cancer cells during the first step of metastasis.

By placing cancer cells outside of these tissue mimics, researchers could observe the invasion process in detail, including measurements of speed and location.

One interesting thing we observed is that not all cancer cells within the same population have the same invasiveness, Li said.Some invaded into the tissue mimics while others did not, which prompted us to look at what gives the invaded cells such an advantage.

Li and her team extracted cancer cells at various distances from the invasion point and subjected these cells to genetic sequencing.

We identified 244 different genes that are differentially expressed between the cancer cells that invaded versus the ones that didnt invade, Li said. This means that using the tool we developed, researchers in the future can develop therapeutics that target some of these genes to halt the cancer metastasis.

We think this type of tool will be quite useful to the community, as cell invasion is important in cancer and also a host of other (non-pathological) processes, like tissue growth, differentiation and repair, Wheeler said.

This research was funded by the National Sciences and Engineering Research Council of Canada, the Canada Foundation for Innovation,the Province of Ontario, and by U of T's Medicine by Design initiative, which receives funding from the Canada First Research Excellence Fund.

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Researchers develop credit-card sized tool to understand how cancer cells invade host tissues - News@UofT

CVM Researcher Develops Tool To Improve Chronic Wasting Disease Resistance In White-Tailed Deer – Texas A&M University Today

Chronic wasting disease is a fatal syndrome found in white-tailed deer populations.

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Christopher Seabury, an associate professor of genomics at the Texas A&M University College of Veterinary Medicine & Biomedical Sciences (CVM), has confirmed that certain aspects of the white-tailed deers response to chronic wasting disease (CWD) are moderately to highly heritable, or passed from parent to offspring, and can be predicted using a custom genomic tool designed by Seabury and his team.

This custom tool, a novel array designed by Seabury, can be used to predict a white-tailed deers responses to CWD exposure with high accuracy and specificity, meaning that the array is likely to become widely deployed for use in a genetic evaluation program aimed at reducing the prevalence of CWD.

Such a program would allow deer farmers, wildlife managers and regulatory agencies to selectively breed the least susceptible deer, thereby building healthier, more CWD-resistant populations. This tool and program could support herd health of both farmed and free-ranging deer populations; although the initial application of this technology is currently focusing on U. S. farmed white-tailed deer.

CWD is a fatal syndrome that causes weight loss, ataxia (as part of a degenerative disease of the nervous system), listlessness and other neurologic symptoms in both farmed and free-ranging U.S. mule deer, elk, moose and white-tailed deer populations.

CWD is recognized as a prion disease, meaning that an infectious misfolded protein (PrPCWD) is instrumental for behavioral changes, emaciation and progressive neurological disease leading to death. Another relevant prion disease known as Scrapie (PrPSc) affects both sheep and goats, and was first recognized in sheep as early as the 18th century.

Importantly, the prevalence of scrapie has been reduced by approximately 85% through afederal eradication program administered by USDA APHIS.

CWD is currently present in at least 26 U.S. states, multiple Canadian provinces and several areas in Eurasia, but its geographic distribution is expanding despite the implementation of surveillance programs that aim to contain and depopulate CWD-positive herds.

Some naturally occurring genetic variation within thePRNP gene which encodes the normal cellular prion protein has previously been associated with enhanced risk for CWD. However, this study clearly demonstrates that while some genetic variation within the PRNPgene has large effects on risk for CWD, selective breeding based uponPRNPinformation alone is insufficient to facilitate a rapid reduction in the overall prevalence of CWD in farmed U.S. white-tailed deer.

Seaburys research published in G3: Genes, Genomes, Genetics used molecular genetic techniques and machine learning to analyze DNA samples from deer with and without CWD.

He and his team confirmed the G96S genetic variant of thePRNPgene as having large effects on risk, while also demonstrating for the first time that genetic variation in other genes collectively explains more differential susceptibility and variation in disease progression thanPRNPalone; thereby necessitating a whole-genome approach to selective breeding.

The novel test designed and validated by Seabury in this study involves a custom Affymetrix Axiom single nucleotide polymorphism (SNP) array, which is used to collect genome-wide DNA profiles from white-tailed deer; for both association mapping and machine learning.

One of the most important things from this initial study is the mean genomic prediction accuracy, which hovers around 81 percent, Seabury said. This means that we can predict with about 81 percent accuracy the phenotype of a tested animal, and that we can accurately estimate the genetic merit of each animal, as it relates to CWD, by producing something called genomically-estimated breeding values.

This novel strategy for producing genomic predictions for risk of CWD in white-tailed deer could be used to mitigate CWD risk in both farmed and free-ranging deer populations.

White-tailed deer are very adaptable and prolific; often reappearing in free-ranging areas where depopulation or herd reduction was attempted to control CWD, Seabury said. Additionally, in regions where indigenous anthrax occurs, and has caused wide-spread dead-loss among white-tailed deer, managers have often reintroduced white-tailed deer by translocation. Wouldnt you like to be able to select deer for replacement that you felt would reduce the populations overall risk for CWD?

Seaburys next goal includes making the test an affordable and reliable tool that deer farmers and wildlife agencies can use to ensure healthier populations of white-tailed deer.

I want to achieve a final array designed to be so cheap that it can be widely used and implemented, Seabury said. Im going to strive to redesign the array to maximize the prediction accuracy, but also minimize the costs.

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CVM Researcher Develops Tool To Improve Chronic Wasting Disease Resistance In White-Tailed Deer - Texas A&M University Today

The Prostate Cancer Foundation and Robert F. Smith Announce New Effort to Address Health Disparities for African American Men – BioSpace

LOS ANGELES, July 21, 2020 /PRNewswire/ --TheProstate Cancer Foundation(PCF) and Robert F. Smith, founder, chairman and CEO of Vista Equity Partners, announce a new effort to reduce deaths from prostate cancer, one of the largest health disparities facing African American men today.

"As African American men are at an increased risk for being diagnosed or dying from prostate cancer, understanding their risk profile and applying this knowledge earlier with strategic detection, care, and decisions about cancer risk management is of utmost importance to address health inequity in the U.S.," said Smith. "This is why I made a personal commitment to help accelerate research, encourage African American men to participate in the study and subsequent testing, and develop new detection strategies that have the power to transform how we diagnose and treat this disease and help save lives."

The research Smith is supporting will lead to the development of the Smith Polygenic Risk Test for Prostate Cancer, a non-invasive, early detection test that will identify a man's lifetime prostate cancer risk using a combination of more than 250 genetic variants obtained from a single sample of saliva or blood. The Smith Test is expected to cost less than $90 USD and will be made available in PCF's dedicated Veterans Affairs (VA) network of Centers of Excellence, including the Robert Frederick Smith Center of Precision Oncology Excellence at the VA Chicago.

The test is part of a larger PCF research initiative to improve the understanding of genetic risk in African American men and transform early detection and imaging strategies, risk management, and clinical-decision making by men at highest lifetime risk of prostate cancer. The research, led by Dr. Chris Haiman, ScD, a genetic epidemiologist at the University of Southern California, and international colleagues is aimed at accelerating the reduction of prostate cancer disparities for African American men by 2030.

Prostate cancer affects more than three million men in the U.S., with one in nine men diagnosed with prostate cancer in his lifetime. African American men are disproportionately impacted. They are 76 percent more likely to develop prostate cancer than Caucasian men, and are more than twice as likely to die from the disease compared to men of other ethnicities. Earlier, strategic detection is a key step in finding a cure and ending the health disparity faced by men of African descent.

"Reducing prostate cancer disparities is at the heart of PCF's mission to end prostate cancer once and for all. This test will democratize access to genetic testing and machine learning algorithms for prostate cancer risk. It will have a historical impact in public health, racial health justice, and cancer research. We are profoundly grateful to partner with Robert to close the health equity gap and spare more men the hardship of a late-stage prostate cancer diagnosis," said Dr. Jonathan W. Simons, CEO of PCF.

Most genomic studies of prostate cancer have focused on men of European ancestry, and there is a vital need for additional resources to develop and optimize a polygenic risk score in those disproportionately affected. This new Smith-PCF initiative will increase the representation of African American men in the study and vastly expand the research to allow Dr. Haiman to quadruple the size of his study cohort, a key step to providing worldwide access to the Smith Polygenic Risk Test as soon as possible.

About the Prostate Cancer FoundationThe Prostate Cancer Foundation (PCF) is the world's leading philanthropic organization dedicated to funding life-saving cancer research. Founded in 1993 by Mike Milken, PCF has raised more than $830 million in support of cutting-edge research by more than 2,200 research projects at 220 leading cancer centers in 22 countries around the world. Thanks in part to PCF's commitment to ending death and suffering from prostate cancer, the death rate is down by 52% and countless more men are alive today as a result. The Prostate Cancer Foundation research now impacts more than 70 forms of human cancer by focusing on immunotherapy, the microbiome, and food as medicine. Learn more at http://www.pcf.org.

Connect with PCF: Facebook | Twitter | LinkedIn

MEDIA CONTACT: Donald Wilson for the Prostate Cancer Foundation(310) 428-4730press@pcf.org

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Bitcoin Surges to $9.3K for First Time in a Week Is it a Fakeout? – Cointelegraph

The price of Bitcoin (BTC), the top-ranked cryptocurrency by market capitalization, surged past $9,300 on July 21 for the first time in over a week. Following a low-volatility range, traders are seemingly turning cautiously bullish in the near-term.

Since late June, Bitcoin has been stuck in a relatively tight range between $9,000 and $9,250. It struggled to see a major price movement causing the volume to slump. After a quick upsurge from $9,150 to over $9,300, traders predict that a volatility spike is imminent.

The price surge coincided with a U.S. stock market rally, driven by a new round of stimulus. U.S. Treasury Secretary Steven Mnuchin said a $1 trillion stimulus deal is in the works.

The performance of top cryptocurrencies in the last 24 hours. Source: Coin360.io

Some traders say a break to the upside is likely, but declining volume is concerning

Several technical analysts say that the recent rally of Bitcoin could lead to a bigger rally in the short-term. Bitcoin faces key resistance levels at $9,550 and $9,800, and BTC saw steep rejections from both areas previously.

Crypto trader Philip Swift pinpointed that the two-month range of Bitcoin since May occurred above the 200-day moving average (MA), indicating that the uptrend of Bitcoin could be intact.

The trader said:

Promising little pump this morning. I suspect this will be the week we finally break out of the dreaded range.

The range of Bitcoin since May was above the 200-day moving average. Source: Philip Swift

Arthur Hayes, the CEO of BitMEX, also expressed his excitement towards Bitcoins minor rally. Hayes said BTC awoke from thee slumber, referring to its low volatility in the past week.

Arthur Hayes tweets about Bitcoins first breakout in over a week. Source: Arthur Hayes Twitter

Michael van de Poppe, a full-time trader at the Amsterdam Stock Exchange, hinted that Bitcoin is cautiously optimistic. He said:

We've got our breaker and bullish move here, as the market is showing strength. I don't think $BTC will accelerate, as it's just still hopping around.

Binance Futures data shows that the majority of traders on the platform are majority long on Bitcoin and Ether (ETH).

Data from Datamish suggests there are substantially more long contracts than shorts in the entire Bitcoin futures market as well. Longs amount to 22,496 BTC, worth around $209 million. In contrast, shorts stand at a mere 5,555 BTC, worth less than $52 million.

Although the 200-day MA technically suggests an uptrend, historical data shows it could easily break down below it. Previous peaks witnessed in July 2019 and February 2020 both rejected above the 200-day MA.

Data from Santiment also shows that the volume of Bitcoin has declined in recent weeks. When an uptrend coincides with declining volume, it could hint at a fakeout.

Researchers at Santiment wrote:

BTC's overall trading volume continues to slide, and with so much focus on altcoins currently, Bitcoin's trading volume hitting a daily value of $12.25B Saturday marked the lowest single-day value since October 5, 2019 (a 9.5-month low).

The trading volume of Bitcoin continues to decline. Source: Santiment

The market remains mixed as BTC grinds through the new week. Technical indicators and macro fundamental factors, like Bitcoins hash rate and low exchange inflows, suggest an uptrend. But the low volume of BTC throughout the past two months remains a variable.

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Bitcoin Surges to $9.3K for First Time in a Week Is it a Fakeout? - Cointelegraph

Bitcoin And Other Crypto-Assets Excluded From Central Bank Experiments – Forbes

A picture taken on January 15, 2020 shows the facade of the Banque de France building in Paris. The ... [+] bank is working with the European Central Bank to re-imagine how new technologies can change the way money works.

The central bank of France is on the verge of conducting a series of sweeping experiments whose lessons could be used to change the way money works. Cryptocurrency wont be included. In a statement from the Banque de France, the nations central bank, which works together with the European Central Bank to determine the monetary policy of the continent, the institution today released the names of eight participants in the experiments and the scope of the work.

Participants are consulting giant Accenture ACN , settlement giant Euroclear, the HSBC bank, French firm, Iznes, etheruem platform LiquidShare, little-known startup, ProsperUS, crypto bank Seba, and Forge, Societe Generales digital capital markets spinoff. The broad parameters of the experiments include everything from testing regulation using digital currency to improve cross-border payments, an analysis of how a central bank digital currency should be made available, and importantly, to explore new methods of exchanging financial instruments (excluding crypto-assets) for central bank money.

The statement from one of the words leading central banks shows how the vaunted institutions are scrambling to learn the best that cryptocurrency, and its underlying blockchain technology have to offer, but only within limits. Neither blockchainthe shared ledger that lets bitcoin existnor the more sanitized word to describe the larger group of technologiesdistributed ledger technology were mentioned by name in the statement. As such, the work also helps define the limits of what any actual adoption of the technology might look like.

The strong mobilization around this call for candidates testifies to the interest of the actors of finance and technology for this approach aiming to explore the potential contributions of a digital money issued by the central bank to improve the functioning of financial markets, in particular interbank regulations, according to a Google GOOGL translation of the statement. A representative of the Banque de France declined to share any additional context.

Over the coming days, the Banque de France will begin conducting experiments with each of the candidates, according to the statement, with some of the projects expected to take as long as multiple months. Candidates were asked to respond to the banks call for applications for CBDC experiments by May 15. The experiments could have far-reaching implications to the decision-making processes for the central bank, which in addition to helping define Europes monetary policy and implement it in France, regulates Frances banks and insurance companies and ensures risk management.

Beyond the confines of France though, lessons learned from the central bank digital currency experiments will be contributed to the international work being led by the Eurosystem, the monetary authority of the European Union. Earlier this month, the bank joined Germanys central bank, the Deutsche Bundesbank, and the European Central Bank in co-hosting a new innovation center in Europe within the framework of the Innovation Hub of the Bank for International Settlements.

In May, European Central Bank executive board member, Yves Mersch, confirmed in a speech at industry conference Consensus, that the European Central Bank was one of at least 66 central banks exploring how lessons learned from blockchain could change the very fabric of what we consider money.

For example, Chinas central bank, the Peoples Bank of China, has taken a giant first-mover advantage in the space, starting its CBDC experiments years ago, and currently testing a working implementation. If successful, one side-effect of CBDCs could be borderless transactions, possibly giving people the choice to store Chinese Renminbi in addition to, or instead of dollars, as a global reserve currency,

Based on what we know of the nearly pervasive experiments around the world looking into the nature of CBDCs, some of the other possible changes to the way money works could include giving citizens accounts at central banks, allowing them to occasionally bypass commercial banks and receive direct access to stimulus checks and more. Another possible, but controversial side-effect of central bank digital currencies could enable online payments while maintaining the privacy citizens have historically enjoyed with cash.

Skeptics of the CBDC concept argue that so long as central banks continue to have the authority to print or issue nearly unlimited amounts of the currency the underlying problems of inflation will continue to drive people to more distributed, deflationary alternatives such as bitcoin, which has a set amount. Other skeptics point to the unlikelihood that central banks will ever actually allow citizens the same privacy they have in the real world, online, and could use the technology as a way to track their own citizens spending habits.

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Bitcoin And Other Crypto-Assets Excluded From Central Bank Experiments - Forbes

Survey: 60% of Bitcoin Investors Will Die With Their BTC If Price Stays Below $10,000 | News – Bitcoin News

About 60% of bitcoin investors are willing to hold their coins until they die if the price fails to breach the key $10,000 level.

Now thats according to a Twitter poll by Peter Schiff. The gold-bug asked bitcoin hodlers: How much longer does the price of #Bitcoin have to stay below $10,000 before you will throw in the towel and sell?

With about 7 hours left for the poll to expire (at Press time), nearly 26,000 people have responded. At least 58% said they will hold the top crypto for as long as it matters, even if that means taking it to their graves.

Another 15%, or 3,900 people, said it will be a year before they decide to sell. Around 14% of the respondents said they will hodl for another three years and 13% for the next decade before opting to exit their positions.

It seems unfathomable that anyone would willingly die holding onto dear bitcoin because the price stagnated below the psychological $10,000 threshold. Rather, it is more plausible that Schiffs poll result illustrates the faith with which investors hold in regard to BTC, even as the price struggles.

Bitcoin bulls have struggled to gain momentum since the Bitcoin network scheduled supply cut of May 11 the event looked upon by many as a potential turning point for a bullish breakout. Previous such events have led to a major rally. Twice the price of BTC broke above $10,000 and twice it was rejected, at one point to as low as $8,600.

Today, BTC is trading at $9,248, down 0.9% over the last 24 hours, according to markets.Bitcoin.com data. The immediate target is to break above $10,000 and stay there. Analysts consider this level as important for sparking BTCs long-awaited price rally.

According to Chainlysis, a crypto data analytics company, most BTC investors do not want sell their assets because they regard it as digital gold. Of the 18.6 million BTC mined as of June 2020, around 60% is held by entities either people or businesses that have never sold more than 25% of the bitcoin theyve ever received.

The firm says only 3.5 million bitcoin or 19% of total circulating supply is actively traded throughout the world. Another 20% of the existing bitcoin supply has not moved from its current set of addresses in five years or longer what Chainalysis called lost bitcoin.

What do you think about the result of Peter Schiffs poll? Let us know in the comments section below.

Image Credits: Shutterstock, Pixabay, Wiki Commons

Disclaimer: This article is for informational purposes only. It is not a direct offer or solicitation of an offer to buy or sell, or a recommendation or endorsement of any products, services, or companies. Bitcoin.com does not provide investment, tax, legal, or accounting advice. Neither the company nor the author is responsible, directly or indirectly, for any damage or loss caused or alleged to be caused by or in connection with the use of or reliance on any content, goods or services mentioned in this article.

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Survey: 60% of Bitcoin Investors Will Die With Their BTC If Price Stays Below $10,000 | News - Bitcoin News

Bitcoin ads must be regulated by UK government, Treasury proposes – Decrypt

The UK government wants to get rid of the misleading and inadequate promotions in the countrys cryptocurrency industry.

Today, Her Majestys Treasury put forward a plan to have the UKs financial regulator, the Financial Conduct Authority, gatekeep the crypto companies allowed to advertise their services in the country.

The government laid out the issue in a July 2018 report: Adverts often overstate benefits and rarely warn of volatility risks, the fact consumers can both grow and lose their investment, and the lack of regulation.

Since the reports publication, the UK government recorded an increase in the number of people using cryptocurrencies. In the past year, the government found that the number grew by 2.35%, from 1.5 million people to 2.6 million people; 35% of British HODLers surveyed said they had been swayed by advertisements.

So, to make sure that crypto companies arent deceiving investors, the Treasury proposes that the FCA assume control over a regulatory gateway that crypto companies looking to advertise their products must pass through.

The governments mostly concerned by fungible assets that can be traded on spot exchangessuch as trading Bitcoin or Ethereum on Binance, for example. Crypto companies advertising investments services (think crypto investment houses and spurious auto-trading companies), exchanges, and airdrops would all have to be approved by the FCA.

Digital collectibles, like CryptoKitties, as well as cryptocurrency assets that operate in closed systems, like crypto-based supermarket loyalty points, would be exempt. If a company promotes their products nonetheless, the FCA can force it to withdraw the advertisements.

Before it puts laws into place, Her Majestys Treasury has opened up its proposal to public consultation; interested parties have until October 26 to do so.

Jumping the gun, Decrypt has reached out to some of the companies that would be affected by this regulation. Some welcome the idea, while others think it would stifle the UKs crypto industry.

I think this is good news, Stani Kulechov, CEO and founder of London-based crypto loans company Aave, told Decrypt. If the government intervention weeds out the scammers, its the right way to go, he said.

Mariana Gospodinova, general manager of Crypto.coms Europe business, likwise told Decrypt that the legislation is a good idea. This move is good for the industry, as it will eliminate dubious scammers trying to cash in on cryptocurrency, she said.

And itll be good for business, too: Gospodinova said itll help distinguish companies that are committed to compliance from the fly-by-night schemes that dupe newcomers out of their funds by selling them snake oil masquerading as cryptocurrency.

That is, so long as the FCAs legislation isnt overly onerous and that the FCA applies a light touchshe contrasted this to New Yorks difficult-to-obtain BitLicense.

But not everyones on board. Konstantin Anissimov, the executive director of crypto exchange CEX.IO, told Decrypt that the regulation could be devastating.

The proposed regulation ispointless since within the spot market, there is a very limited amount of misleading one can do as the fees are clear, and the prices of the crypotasset are also clear, he said.

All this will do, then, is make it more difficult to market crypto products, according to Anissimov. He said this could be devastating for such a fast-paced industry as crypto and will most likely hurt the retail investors who will no longer be able to utilize the best market opportunities.

On the other hand, Anissimov conceded that one benefit of the regulation could be a potential increase in the public's trust in crypto, which could then lead to a greater uptake of crypto among the masses.

But only if the whole process is not overburdened with bureaucracy and delays, he said.

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Bitcoin ads must be regulated by UK government, Treasury proposes - Decrypt

Michael Caselli impressed by innovation of Bitcoin SV platform – CalvinAyre.com

Bitcoin was always designed to be a perfect match for the gambling industry, with its ability to conduct cost efficient and fast payments, while also providing an immutable audit trail that regulators love, and data networking opportunities for enterprising developers. CG London was a great exhibition of this, and it brought out non-executive chairman ofClarion Events Michael Caselli, who reflected on gamblings history with Bitcoin.

Our very own Rebecca Liggero Fontana bumped into Caselli at the event and asked what brought him out. Its right down the road, its the ideal location for me, he said. Gaming industrys here, its a huge global hub and I thought I better come down because I know a lot of other guys from the industry wanted to come down, and are coming down. And whats interesting, anything blockchain is exciting, theres got to be an application that were looking for now. A lot of companies are innovating and trying to find their applications for anything blockchain, and Bitcoin SV is just a really great platform with good throughput, good transaction volumes, the ability to do quite a lot of stuff on the application layers that you cant do on some of the coins, and it just makes a lot of sense that the gaming industry is coming down and Im here to support.

Bitcoin SV, having finally unleashed the power of unlimited scaling on the blockchain, was impressing plenty of visitors at the conference, and Liggero Fontana asked what potential Caselli saw in it. Decentralized solutions are good for a number of different things like exchanges, he said. Trust is an issue, so where theres ever a trust issue for any application, then theres a good solution for that. Trust issues may exist in countries which are yet to regulate, which dont have a regulator thats overseeing whats going on, and then players could really self-regulate whats happening by using an immutable blockchain.

But while Bitcoin SV has only recently started unleashing the true potential of blockchain technology, the concept itself has been around a number of years, and Caselli reflected on how the gambling industry has approached it. We were at fever pitch maybe six, seven years ago whenever things started to kick off, when Bitcoin got to its, you know, $100 value and then climbed to a thousand dollars, he said. And that was exciting and everyones looking at, saying Where does this work, where does this work? And I think there was a lot of adaptation at that time to kind of move the systems over on the payment side of things. And then when smart contracts came out, there was a whole bunch of people launching tokens and launching projects so they can go and they could fund themselves, create some applications in gaming.

Caselli still feels that excitement, and with the ability to store both value and data, he sees big things coming. With the ability to create applications, who knows where were going to go in the future.

Weve interviewed Caselli recently about how the pandemic has affected the gambling industry. You can catch that chat, and all of our future videos, by subscribing to our CalvinAyre.com YouTube channel.

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Michael Caselli impressed by innovation of Bitcoin SV platform - CalvinAyre.com

Bitcoin And Modern Soft Fork Activation Bitcoin Magazine – Bitcoin Magazine

Taproot, a proposed protocol upgrade that would improve Bitcoins privacy and flexibility, is in its late stages of development. Bitcoin Core contributors agree that the upgrade would benefit Bitcoin, and so far it generally appears to be welcomed by the wider Bitcoin ecosystem as well. Its therefore likely that Taproot will make its way into a Bitcoin Core release, with other Bitcoin implementations possibly to follow.

But one question remains: how should the Bitcoin network itself upgrade? Taproot is a consensus protocol change, which means that Bitcoin nodes must somehow switch from the old rules to the new rules without splitting the network into factions enforcing different rules. For various reasons, this has in the past sometimes proven to be a challenge.

Improved strategies to activate protocol upgrades are now being contemplated.

The good news is that Taproot will be a soft fork. This type of upgrade adds or tightens rules as opposed to a hard fork which removes or loosens rules. The nice thing about adding or tightening rules is that anything that an upgraded node considers valid, a non-upgraded node considers valid, too. (If an old node accepts both transaction types A and B, but new rules only allow transaction type A, the old node would remain compatible on a network enforcing the new rules.)

Bitcoins earliest soft forks were activated though flag days. Developers (in particular, Satoshi Nakamoto) embedded a future date in the code of a new Bitcoin software client release, specifying a point in time where upgraded nodes would enforce the new rules. Miners and users were encouraged to upgrade before that date to avoid network splits. (As an aside, in those days, miners and users were more often the same people than they are today.)

Since non-upgraded nodes remain compatible with new rules, a handy benefit of soft forks is that if a majority of hash power enforces the upgrade, the entire Bitcoin network finds consensus on their version of the blockchain. This also means there is less of a pressing need for all nodes to be upgraded immediately when the new protocol rules are enforced, allowing users some flexibility. (Though users are encouraged to upgrade nonetheless; they are ultimately the ones enforcing the new rules by rejecting transactions and blocks that break them.)

Since about 2012, soft forks have increasingly utilized hash power as a coordination mechanism to coordinate a switch to new rules. By embedding a bit of data in their blocks, miners can signal to other miners and the rest of the network that they upgraded their software, and thus are ready to enforce the new rules. Once enough hash power signals support, all upgraded nodes are triggered to enforce the new rules.

Over the course of a few upgrades, this strategy evolved into Bitcoin Improvement Proposal 9 (BIP 9). BIP 9 was, for example, the mechanism used to activate Bitcoins last soft fork upgrade, Segregated Witness (SegWit). Miners were given a year to activate the upgrade, requiring 95 percent of blocks within any difficulty interval to include a readiness signal bit. If after a year this hadnt happened, the activation period would expire, and the upgrade would have failed. (It could then of course simply be tried again.)

For SegWit, however, BIP 9 did not play out smoothly. As with some of the previous upgrades, some miners probably didnt get around to upgrading for some time due to apathy: there often isnt a very big incentive for miners to upgrade fast. But a bigger problem was that some miners had come to understand the signaling process as a sort of vote on the upgrade, where instead of signaling readiness, they would (or would not) signal support for it. Worse, some miners ended up using this vote to block the upgrade in order to try and gain political leverage over the Bitcoin development process, and/or they voted against the upgrade in order to covertly benefit from a quirk in the Bitcoin protocol which the upgrade would fix.

After an extended period of intense drama, SegWit ultimately did activate, but only after alternative Bitcoin clients included new activation schemes. BIP 148, included in the BIP 148 client run by some users, was programmed to only accept blocks signaling support for the protocol upgrade starting on a flag day. Meanwhile, BIP 91, included in the btc1 client and run by miners just ahead of the BIP 148 flag day, effectively lowered the hash power requirement from 95 percent to 75 percent. Faced with a potential split network and a possible loss of income, the obstructing miners conceded. But for most Bitcoin Core developers, BIP 9 had revealed itself to be a suboptimal solution, and they started thinking of alternatives.

BIP 8 was an early alternative for BIP 9, proposed by BIP 148 author Shaolinfry and Bitcoin Knots and Bitcoin Core contributor Luke-jr. It initially resembled BIP 9, but with one crucial difference: instead of the upgrade failing after a year of insufficient hash power support, it would do the exact opposite and activate the soft fork at that point in time. Similar to a flag day, all upgraded nodes would from then on start enforcing the new rules. Miners whod still have failed to upgrade would risk mining blocks that upgraded miners and users would reject.

The main idea behind BIP 9 is that assuming of course that users upgrade miners cant block the soft fork and therefore cant use this leverage to their benefit. They can speed activation up and help coordinate a smooth protocol upgrade, but the upgrade will eventually happen even if they dont activate it themselves.

A more recent draft of BIP 8 includes some notable changes. For one, BIP 8 allows nodes to be configured for two different policies when the signaling period is about to expire: forced activation, as explained in the previous two paragraphs, or no forced activation, like with BIP 9. Furthermore, instead of activating the upgrade itself, nodes (if so configured) actually enforce signaling for the upgrade. Blocks that do not signal support for the upgrade are then rejected, hence still guaranteeing the upgrade, at least for the upgraded nodes. The combination of these two changes has the interesting property that if a majority of all Bitcoin hash power is compelled to signal support for the upgrade, even BIP 8 nodes that arent configured to enforce signaling will go along with the upgrade,

An argument against BIP 8, and its forced signaling (or automatic activation) in specific, is that it can be risky, especially on a shorter timeline. If a hash power majority and at least some users dont upgrade, this scheme could split the network between upgraded and non-upgraded nodes. Assuming most users support the upgrade, this would likely resolve in favor of the upgraded part of the network eventually. But non-upgraded users would risk losing funds in the meantime, while non-upgraded miners would waste hash power to the detriment of Bitcoins security.

This risk is probably best countered by offering enough time to upgrade. Unfortunately, not everyone agrees on how much time is enough; some think forced signaling could start within a year, others believe it should take several years.

Another complication with BIP 8 is setting defaults for forced signaling. If forced signaling is switched off by default, users could find themselves uncoordinated, increasing the risk of network splits. If on the other hand forced signaling is chosen as the default in a Bitcoin Core release, the historically widespread adoption of Bitcoin Core virtually guarantees that the upgrade will happen. Some believe this would give Bitcoin Core developers too much influence over Bitcoins protocol rules. For this reason, BIP 8 coauthor Luke-jr prefers BIP 8 with forced signaling to exclusively be deployed through special clients, similar to the BIP 148 client.

Others argue that Bitcoin Core developers always release software to their best judgement, while keeping user demand in mind and avoiding contentious upgrades; setting BIP 8 defaults should be no exception to this policy. If anyone disagrees with the choices Bitcoin Core developers make after all, they can simply choose not to upgrade to a new release or even fork the Bitcoin Core code to launch a competing client altogether.

While Bitcoin Core developers indeed seek to take user demand into consideration and try to avoid contentious upgrades, not everyone is convinced this is always perfectly possible. Perhaps concerns about a proposed upgrade only surface when the software is deployed in a new release. Perhaps whole new issues arise after this release. Or perhaps Bitcoin Core developers simply missed something.

This is one reason why Bitcoin Core contributor Matt Corallo proposed a strategy dubbed Modern Soft Fork Activation. Modern Soft Fork Activation consists of three steps, together essentially realizing a combination of BIP 9 (or: BIP 8 without forced signaling) and BIP 8 with flag day activation (though forced signaling could be an option as well).

As the first step, BIP 9 would allow miners to activate the soft fork through hash power. If miners dont activate it in (say) a year, the first activation window expires. Then, as the second step, developers take some time to analyze why activation failed, and reconsider the proposal if they do find a concern with it. If they find there was no problem with the proposal, however, the third step is redeployment of the soft fork, this time using BIP 8 with flag day activation: miners get another chance to activate the proposal with hash power, but if they fail again, the soft fork activates when this second signaling period ends. (During this second signaling period, the hash power activation threshold could also be incrementally lowered over time, Bitcoin Core contributor AJ Towns suggests.)

By explicitly committing to BIP 8 redeployment if it turns out theres nothing wrong with the proposal, Corallo believes the strategy would offer the benefits of BIP 9 without the downside. The code is put out there during the first signaling period for everyone to consider, miners can coordinate a smooth upgrade if they so choose, and with no forced activation developers can take their time to reconsider the proposal if activation does initially fail. Meanwhile, miners would have much less to gain from blocking the upgrade for no good reason, as everyone knows it will eventually activate anyways.

The main argument against Modern Soft Fork Activation is that without miner cooperation, the process would take relatively long, and some consider the BIP 9 step a waste of time altogether. Corallos original proposal includes one year of BIP 9 signaling, followed by six months to reconsider, and finally two years of BIP 8 signaling before automated activation: a total of three-and-a-half years. While this timeline is of course not set in stone yet, shortening the different steps by too much would leave less time for reconsideration and/or upgrading (increasing the risk of network splits).

Due to the long time until potential forced activation, some also argue that miners can try and gain some political leverage after all: they can delay the upgrade for years.

Another, recent suggestion circulating through Bitcoins tech channels is perhaps best described as a bit of a merger between BIP 8 and Modern Soft Fork Activation, at least in spirit. The unnamed proposal would deploy a long BIP 8 signaling period, perhaps as long as Modern Soft Fork Activations three-and-a-half years, after which forced signaling triggers. However, if after (say) one year the upgrade didnt activate yet, developers would take some time to reconsider the proposal, like they would with Modern Soft Fork Activation.

If developers would find no problem with the proposal, and instead were to conclude that it simply hadnt activated due to miner apathy or another invalid reason, they could opt to deploy a new soft fork in the style of BIP 91, used during SegWit activation. This would effectively lower the hash power threshold for activation, presumably speeding up the process.

If, on the other hand, developers would find a problem with the proposal after all, they could deploy a new soft fork that would fix the problem, or even undo the original soft fork (in this case, Taproot) altogether. Assuming Modern Soft Fork Activations three-and-a-half-year timeline until forced signaling, there ought to be enough time left to take care of this.

The main argument against this proposal is probably that its not very elegant to deploy a soft fork that undoes another soft fork, if so needed. More concretely, it requires that miners and users upgrade to new releases before deadlines are reached, or risk splitting the network.

Finally, as a bit of an outlier idea, Bitcoin Core contributor Jeremy Rubin suggested that a concept he invented called Probabilistic Bitcoin soft forks, or Sporks, might be more incentive compatible than typical hash power enforced softforks.

The heart of the problem of BIP 9, Rubin argues, is that miners can delay upgrades at no cost of their own. Simply refusing to signal readiness for an upgrade is free, while it potentially offers them political leverage.

With Sporks, the readiness signal is no longer taken from a bit of data that miners include in the blocks they mine, but derived from the block header hash: the randomly generated proof of work they produced by investing time and resources. Upgraded nodes would agree that a small subset of valid block header hashes statistically to only be found every six months or so would trigger the upgrade.

Per the randomness of hashes, a miner would not control whether he produces regular block header hashes or upgrade-activating block header hashes; hed statistically just happen to churn out one of the latter sporadically. So, if his invested resources happen to generate an upgrade-activating block header hash, hed have two choices. Either, publish it to the Bitcoin network, earn the block reward, and activate the soft fork. Or, withhold from publishing, delaying the soft fork by about six months on average in our example but in doing so also giving up the block reward. Delaying the upgrade would come at a significant cost.

The main problem with Sporks right now is probably that its a relatively new idea, that hasnt been developed yet let alone tested in the wild. While some do consider the concept interesting, its as of yet not the most likely contender for Taproot activation.

Authors note: The debate on soft fork activation (and Taproot activation in specific) is in flux; this is a non-exhaustive overview of the different upgrade proposals, especially when it comes to variants of the proposals with alternative parameters and other tweaks, and all their pros and cons.

Another idea, which has been gaining some traction since this article was written (mostly), is to first deploy BIP 8 with a relatively long signaling period (say, two years), configured without forced signaling at the end of this signaling period. This allows miners to activate the soft fork relatively normally, as they have done several times in the past. However, if after some time (say, six months) the soft fork isnt activated, and there doesnt appear to be a good reason for the delay, a new client can be released with BIP 8 configured to force signaling near the end of the existing signaling period, or sooner. Assuming most miners then activate the soft fork either before or during this forced signaling period, both sets of BIP 8 nodes (with and without the forced signaling configuration) would enforce the soft fork on activation.

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Bitcoin And Modern Soft Fork Activation Bitcoin Magazine - Bitcoin Magazine

‘Wonder Woman’ Illustrator and British Artist Terry Flaxton to Sell Ethereum-Backed Art – Bitcoin News

The non-fungible token (NFT) and blockchain-backed collectible economy continue to see demand and the digital art market Makerplace has seen enormous growth recently. A number of well known artists have started to participate, as work from the acclaimed comic book illustrator Jose Delbo and 4K video art from Terry Flaxton will be sold on the premier market for rare digital art.

Just recently news.Bitcoin.com reported on the growing blockchain-backed metaverse and the non-fungible token (NFT) evolution. In the report, it was discussed how the sales of blockchain-powered non-fungible token sales crossed the $100 million mark.

Not only is there more than 18,500 wallets on Opensea, the largest NFT marketplace, but another marketplace dubbed Makerplace is seeing a lot of attention from buyers and popular artists. Makerplace is essentially a market for blockchain-backed digital art collections. The website states:

Every digital creation available through Makersplace is an authentic and truly unique digital creation, signed and issued by the creator made possible by blockchain technology. Even if the digital creation is copied, it wont be the authentic and originally signed version.

One specific artist who will host artwork for sale on Makerplace is the British artist Terry Flaxton who is well known for his analog video content, photography, film, and sound composition work. Flaxton has held over 200 exhibitions globally and he will be selling a 4K video project called Under Every Desert a Sea.

Currently, there is a pending offer for one out of the ten Flaxton-created 4K videos being sold for 2.2 ETH ($512). Flaxtons video on Makerplace is also linked through Opensea and the listings description says:

Under every Desert a Sea began its life with images of the Mojave desert that are now so abstracted they appear to be water.

Another well known artist who will be featured on Makersplace web portal will be the comic book illustrator who worked on the DC Comic Wonder Woman series from 1976 to 1981. The comic book artist Jose Delbo also worked on the Thundercats, Transformers, and Brute Force comics in the eighties and nineties for Marvel.

On July 23, 2020, Delbo will be selling a digital Superman drawing and a digital comic book as well. Reports note that Delbo will be answering questions about his digital work during an exhibition hosted in Decentraland.

The art scene worldwide is steadily transforming into an online art industry, and digital art sales are growing every year. At the current growth rate, blockchain and NFT markets like Makerplace and Opensea may someday outshine popular digital art venues like Redbubble, Artfinder, Artplode, Ugallery, and Saatchi Art.

In contrast to the traditional digital art marketplaces that have transpired during the last few years, markets like Opensea and Makerplace sell blockchain-based and NFT art with immutability.

Sales on both markets can be seen in real-time every day and people are spending their precious cryptocurrencies on digital art. For instance, a few pieces of digital art that recently sold on Makerplace include works like Vandalism ($333), Rudbeckia ($153), and a form of pixelated art called Pxlpet Not a Virus ($617).

What do you think about digital art being sold on Opensea and Makerplace? Let us know in the comments section below.

Image Credits: Shutterstock, Pixabay, Wiki Commons, Art by Jose Delbo, Makerplace, Terry Flaxton, Opensea,

Disclaimer: This article is for informational purposes only. It is not a direct offer or solicitation of an offer to buy or sell, or a recommendation or endorsement of any products, services, or companies. Bitcoin.com does not provide investment, tax, legal, or accounting advice. Neither the company nor the author is responsible, directly or indirectly, for any damage or loss caused or alleged to be caused by or in connection with the use of or reliance on any content, goods or services mentioned in this article.

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'Wonder Woman' Illustrator and British Artist Terry Flaxton to Sell Ethereum-Backed Art - Bitcoin News

Tesla Eating Bitcoins Lunch as Realized Volatility Hits 3-Year Low – Cointelegraph

Bitcoin (BTC) set another dubious record on July 15 as realized volatility sank to its lowest in three years.

According to data from on-chain analytics resource Skew, 30-day realized volatility recorded its smallest reading since 2017 this week.

Realized volatility refers to volatility as defined by various timespans. Low volatility tends to concern traders and analysts, particularly over extended periods, as a kickback is all too often triggered afterward.

Earlier this month, 10-day realized volatility hit 20%, its lowest since the period immediately before BTC/USD crashed to $3,100 in December 2018.

As Cointelegraph reported earlier this month, trading volumes were also down at the time, fuelling expectations that volatility would soon return to the market.

Since then, Bitcoins anticipated big move has yet to appear, with a trading corridor between $9,000 and $9,500 remaining in place.

BTC/USD realized volatility comparison. Source: Skew/ Twitter

For Cointelegraph Markets analyst filbfilb, however, there was plenty of potential for a major correction towards $8,000. Specifically, he told subscribers of his Telegram trading channel on Tuesday, the 20-week moving average (MA) at $8,200 provided a realistic support level. Alternatively, BTC should reclaim its 50-day moving average, currently close to $9,400.

Overall my position remains very cautious, he summarized.

Until then its just sideways chop until proven otherwise so I'm happy to sit that out and wait for confirmation.

In the meantime, Bitcoin is providing little inspiration, with even Tesla stock beating it on volatility.

#Bitcoin realized volatility on a three years low, Tesla is eating bitcoin's lunch! Skew commented.

Tesla has surprised by posting multiple new highs despite multiple calls for a massive correction continuing for several months. Since its recent bottom on March 18, $TSLA has gained over 300% to trade at $1,516 at press time.

Even at $1,200, Teslas market cap was over 30% larger than Bitcoins.

Tesla stock price eight-month chart. Source: TradingView

Tesla CEO Elon Musk continues to be known as a possible cryptocurrency supporter, with mysterious tweets on topics from Bitcoin holdings to Dogecoin (DOGE) causing considerable interest among users.

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Tesla Eating Bitcoins Lunch as Realized Volatility Hits 3-Year Low - Cointelegraph

Windmill Brixton hosts thrash live-stream – Brixton Blog

Oozing Wound. Image: Joe Martinez Jr

Chicago band Oozing Wound are live-streaming a full show from the The Windmill, Brixton, on Saturday 18 July from 11am to 11pm British summer time (UTC+01)

The live video will be streamed in HD quality byMusic Everywhere.

They suggest that interested people shouldregister in advanceto avoid problems in catching the stream.

Oozing Wounds label Thrill Jockey say they are a mass of contradictions; weed lovers whose music hits with a breakneck head-banging force, dealing with nihilism, yet remains fun.

Oozing Wound emerged from the Chicago underground noise warehouse scene and their music is equal parts sludge and thrash, noise and riff-loaded rock.

Guitarist and vocalist Zack Weil, drummer Kyle Reynolds and bassist Kevin Cribbin blend ferocious energy, sonic experiments and blunt lyricism on their latest recording,High Anxiety.

The Windmill is currently operating as a socially distanced pub from 5 to 11pm Monday to Thursday; from 5pm to 1amon Fridays; noon to 1am on Saturdays; and noon to 11pm on Sundays.

https://www.crowdfunder.co.uk/savewindmillbrixton

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Windmill Brixton hosts thrash live-stream - Brixton Blog

Is this the sanest debate on race yet? – The Spectator USA

The race debate is rapidly descending into a one-note diatribe where white accountability has become the only game in town. White liberal voices now dominate an increasingly febrile narrative but alongside mainstream flagellations about systemic racism and white supremacy, a less hysterical, more nuanced discussion is taking place.

Black centrist and conservative intellectuals have been quietly trying to unpick whats really been going on across western democracies. Their conclusions run counter to the mainstream story we are all being impelled to sign up to, namely that injustice runs deeper than mere skin color.

Conservative economist and social theorist Thomas Sowell, who recently turned 90, has been trying to open up just such a debate for over five decades but media elites have largely ignored his well-mannered persistence in favor of a noisier, more divisive grievance lobby. Sowell, currently a senior fellow at Stanford Universitys Hoover Institution, has criticized simplistic arguments around reparations and social justice, arguing that a culture of victimhood, stoked by white liberals is actually holding black men in particular back. In his books The Economics and Politics of Race,Ethnic AmericaandAffirmative Action Around the World, Sowell suggests that many problems identified with African Americans are anything but unique. He argues that for equality to exist, the most disadvantaged in our society need to be lifted out of the prison of low expectation and victimhood regardless of race. Rather than encouraging the most vulnerable to destroy the moral virtues and institutions designed to play to their better natures and thus improve life-chances, Sowell believes we should be setting in place measures that encourage full participation in the structures that have kept America functioning across the centuries and yes that includes embracing capitalism and the nuclear family. Instead of focusing entirely on the unfairness of the system, those in power should be inspiring a generation to better themselves through a radically improved education system, a return to personal responsibility and a belief in something beyond the narrow confines of the self in other words workable solutions that avoid empty nihilism and easy despair.

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Black conservatives such as Sowell have always struggled to be heard above the din of the ideologues but now a younger, more vocal demographic has entered the fray via podcasts and long form discussion forums. This week biologist and evolutionary theorist Bret Weinstein assembled a smorgasbord of mostly young African American academics in a fascinating two-hour round table discussion that tries valiantly to unravel the root causes of the current malaise. One of the guests, Chlo Valdary who developed the Theory of Enchantment, an innovative framework for social emotional learning, believes that America is experiencing a crisis of meaning and that spiritual undernourishment has led to a retreat into polarizing groupthink where the cult of diversity and inclusion has singularly failed on its promise to unite. In this expanding spiritual void, politics has become the new religion and the popularity of books such as Robin diAngelos White Fragility reflect a culture that demands we turn on ourselves rather than seek out solutions. But Valdary remains optimistic, believing that the majority of Americans have grown tired of being whipped into a frenzy by an increasingly infantilized, Twitter-mob-obsessed media.

Elsewhere black conservative thinkers such as Larry Elder and Candace Owens are daring to push back against the current orthodoxy even if that means being demonized and hounded by an indignant, mainly white liberal stronghold who simply cannot stomach dissenting voices especially from a racial demographic they believe owes them unwavering loyalty.

Anyone who feels disheartened by the culture wars rapid descent into ad hominem attack and empty posturing should seek out these brave new voices who seem determined to unite rather than divide.

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Is this the sanest debate on race yet? - The Spectator USA

Art, beauty and the task of humanities – Daily Times

Man can live without science, he can live without bread, but without beauty, he could no longer live because there would no longer be anything to do to the world. The whole secret is here, the whole of history is here. (Dostoevsky)

Laotzes and Kants respective remarks about beauty as the usefulness of the useless, and purposiveness without purpose, are recalled in Martha Nasubaums choice of the title of her work Nor for Profit: Why Democracy Needs Humanities.

Given the modern penchant for utility and commodification that reserves only a small corner for arts in museums and seeks profit by organising art exhibitions, and impoverished modern souls not ready to live and die for beauty, the twentieth century has been the ugliest as Ananda Coomaraswamy noted. Our standard references to immortal works of art and architecture usually go to ancient or medieval times against traditional cultures that glorified God by cultivating beauty within and without,

It is imperative to take stock of arts that have been the temple of beauty and are today widely sought to partly fulfil our hunger for transcendence. We need to take note of the role of arts and humanities in the central task of fashioning humans and giving them the motivation to live soulfully or meaningfully and in the refinement of culture as against civilisation, (a distinction often ignored). Cultivating beauty, which is said to be the fulfilment of religion (Ihsan is Husn paida kerden) in a famous prophetic tradition (hadith-i-Jibriel) is what has been forgotten despite a penchant for the so-called beauty industry.

Cultivating beauty is what has been forgotten despite a penchant for the so-called beauty industry

According to all traditions, it is possible to reclaim the paradise whose image we harbour deep inside and it is education that involves humanities that has a role here. In an age when politicians and even universities might claim that the humanities dont matter and we ought to steer students into science, technology, engineering and math and we find such things as the recent report of the American Academy of Arts and Sciences on the crisis in the Humanities entitled The Heart of the Matter, philosopher and novelist Rebecca Goldstein has been, thus, paraphrased by a reviewer: The humanities assert the sanctity of the individual, help us puzzle out the meaning of existence, teach us to examine our assumptions and urge us to consider others assumptions, she said. The study of the humanities might be under siege right now, but it will prevail, she said. Nietzsche, whose fascination with a sort of post-religious or supra-religious mysticism is little appreciated, didnt fail to recognise that religion was useful for providing meaning, community, and helping to deal with the problems of life. His first suggestion was to replace religion with philosophy, art, music, literature, theatre, and other parts of the humanities to provide similar benefits. Art indeed has been central to postmodern philosophers in the task of overcoming nihilism. It is central to Nietzsche and Heidegger and we can find its contemporary articulation in All Things Shining: Reading the Western Classics to Find Meaning in a Secular Age by Hubert Dreyfus and Sean Dorrance Kelly. The role of art, of tragedy, of play, of beauty, of everything, that humanities engage with is writ large in the pages of every contemporary text that treats, in non-religious or non-theistic terms, the question of meaning. Arnold has been proved right. It is another matter how far this endeavour succeeds and whether we need to contend with it.

It is sad to note that despite realising the significance of art and beauty, they stand exiled from our midst. We have failed to take sufficient note of pleas of artists wedded to beauty. Against traditional man, we have largely forgotten beauty in our houses, in our surroundings, in cities, in villages, in souls. And that explains suffocating lives we live. It is museums that are beautiful and they are generally from ages past when mans religion was a beauty and not utility. Today, our architecture is, generally speaking, designed for utility or vanity. And that has given us a largely ugly, homogeneous, and inhospitable world where all cities look alike and you can find suffocating monotony of banks, malls, schools, hospitals that are designed without regard for vivifying symbolism and for the dead customers/clients/alienated individuals or hired workers. They are best for the dead.

To be true to human or better mans divine image is the heart of humanities as traditionally conceived. Humanities are not to be reduced to sciences but taken as guardians of culture, as creators of value that others then exchange. In a country where the role of God/Sacred or religion is considered important in the framing of the constitution, humanities and their place and funding need to be a priority even if it would be led to question current framing of humanities in the dominant secularizing episteme. Humanities are central to the task of fashioning souls so should be autonomous as madrasahs have been or funded by the community.

Or Madrasahs have to be integrated to universities or revitalized in the classical sense when they performed the role of humanities. A few suggestions from Manazar Ahsan Gilani and Newman regarding marrying the classical idea of university/madrassah with the modern institutions substituting them are worth considering in this context.

Beauty, as the splendour of the Truth and attractive power of the Good or perfection, is also a noetic (knowledge giving) beside an aesthetic notion and satisfies that longing to know the Real or what is considered absolute. Invoking the theology of the aesthetic and emphasising reading art as a ritual for purification and support to contemplation one could counter pervasive crisis of meaning or values in postmodernity that has impacted humanities construction of the human. Martin Lings study Shakespeare in the Light of Sacred Art and Harold Blooms Shakespeare: The Invention of the Human may be read to retrieve the torn and forgotten image of the human, pontifical theomorphic man in the wake of the dominance of sciences at the cost of humanities in the modern world.

The writer can be reached at marooof123@yahoo.com

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Art, beauty and the task of humanities - Daily Times

New Report On, Healthcare Nanotechnology (Nanomedicine) Market 2020 Global Impressive CAGR of 0%, Top Countries Industry Trends, Share, Size, Demand,…

Worldwide Healthcare Nanotechnology (Nanomedicine) Market 2020 Provides Market Share, CAGR, Production, Consumption, Revenue, Gross Margin, Price And Market Manipulating components of the Healthcare Nanotechnology (Nanomedicine) business in worldwide areas. This report is extensive numerical investigations of the Healthcare Nanotechnology (Nanomedicine) business and gives information to making procedures to expand the market development and achievement. The Report additionally gauges the market size, Price, Revenue, Gross Margin and Market Share, cost structure and development rate for dynamic.

The report provides a detailed evaluation of the market by highlighting information on different aspects which include drivers, limitations, opportunities, and threats. This information can help shareholders to make suitable decisions before investing.

Brief Description about Healthcare Nanotechnology (Nanomedicine) market:

The global healthcare nanotechnology market was valued at USD 156.56 billion in 2017. This market is projected to grow at a compound annual growth rate (CAGR) of 15.1% from 2017. North America dominates the market, and is expected to maintain its position over the forecast period.

Rising applications in Oncology

Nanomedicine is a promising mode of cancer treatment and has several applications in oncology. Cancer has a major impact on United States and across the world. As per WHO, cancer is found to be one of the major causes of mortality and morbidity worldwide, with approximately 14 million new cases in 2012 and 8.2 million were the cancer-related deaths. Therefore the demand for nanomedicine in the market was in order to curb such high incidence rate and is expected to boost market. Researchers have been working on improvisation of techniques, to deliver chemotherapeutic agents precisely at the Nano level in tumorous tissues. Nanoscale objects are used by themselves or as parts of larger devices containing multiple nanoscale objects and due their small size, nanoscale devices can readily interact with the biomolecules on both the surface and the inner cells and they have the potential to diagnose and treat cancer. Nanoparticles are majorly been used as nanocarriers, to deliver the cytotoxic drugs to the tumor cells and tissues. The increasing incidence of cancer and importance of nanomedicine in modern cancer treatment procedures, are expected to drive the nanomedicines demand during the forecast period.

Huge costs of the medical devices

Cost is the main factor that is often overlooked, which is specifically important in the face of ever increasing healthcare cost and unpredictable reimbursement environment. Nanomedicines are no different; there are several FDA approved nanoparticle-based products in the market, which can be compared with their non-nanoparticle based counterparts. Although these formulations may be more efficient and less toxic than their counterparts, their costs may also be significantly high. The average cost per dose of anticancer drug doxorubicin is about USD 62-162, compared to USD 5,594 for Doxil, which is a nanoparticle containing doxorubicin. Similarly, the average cost per dose of anticancer drug Abraxane, a paclitaxel nanoformulation, is USD 5,054. Therefore, owing to the inability of the industry to find a cost-effective method of scaling up the production, the cost of nanomedicine therapies is likely to remain high over the forecast period. This high cost of nanoparticle-assisted medicine, relative to its traditional counterparts, is hindering the growth of the market.

US Healthcare Nanotechnology Market

The US-based pharmaceutical companies believe that nanomedicines is the next big thing, as it has been opening up newer and has more accurate options for the target drug delivery, and resulting in very few side effects. The Swiss Groups Kadcyla received the approval of the United States in February 2017. The product treats breast cancer with very less side-effects. In addition with the booming R&D, United States has also initiated several measures in the recent times, to advance and develop the nanotechnology applications in healthcare. Owing to the large geriatric population, increasing need for diagnostics, growing need of augmented cancer therapies, government initiatives, and increasing awareness of nanomedicines, the US healthcare nanotechnology sector will witness substantial growth during the forecast period.

The key players in the market are ABBOTT LABORATORIES, COMBIMATRIX CORPORATION, GE HEALTHCARE, SIGMA-TAU PHARMACEUTICALS Inc., JOHNSON & JOHNSON, MALLINCKRODT Plc, MERCK & COMPANY, Inc., NANOSPHERE, Inc., PFIZER, and CELGENE CORPORATION.

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Major Countries play vital role in Healthcare Nanotechnology (Nanomedicine) market:

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The report provides a detailed evaluation of the market by highlighting information on different aspects which include drivers, restraints, opportunities, and threats. This information can help stakeholders to make appropriate decisions before investing.

Detailed TOC of Global Healthcare Nanotechnology (Nanomedicine) Market Segmented by Platform, Purpose, and Geography Growth, Trends

1.Introduction

1.1 Study Deliverables

1.2 General Study Assumptions

2.Research Methodology

2.1 Introduction

2.2 Analysis Methodology

2.3 Study Phases

2.4 Econometric Modelling

3.Executive Summary

4.Market Overview and Trends

4.1 Introduction

4.2 Market Trends

4.3 Porters Five Force Framework

4.3.1 Bargaining Power of Suppliers

4.3.2 Bargaining Power of Consumers

4.3.3 Threat of New Entrants

4.3.4 Threat of Substitute Products and Services

4.3.5 Competitive Rivalry within the Industry

5.Market Dynamics

5.1 Drivers

5.2 Restraints

Continued

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New Report On, Healthcare Nanotechnology (Nanomedicine) Market 2020 Global Impressive CAGR of 0%, Top Countries Industry Trends, Share, Size, Demand,...

Global Healthcare Nanotechnology (Nanomedicine) Market 2020: Key Manufacturers, Industry Share, Size, Growth Factors, Regional, and Competitive…

Final Report will add the analysis of the impact of COVID-19 on this industry.

Global Healthcare Nanotechnology (Nanomedicine) Market Research Report 2015-2026 is a historical overview and in-depth study on the current & future market of the Healthcare Nanotechnology (Nanomedicine) industry. The report represents a basic overview of the Healthcare Nanotechnology (Nanomedicine) market share, status, competitor segment with a basic introduction of key vendors, top regions, product types and end industries. This report gives a historical overview of the Healthcare Nanotechnology (Nanomedicine) market trends, growth, revenue, capacity, cost structure, and key drivers analysis.

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The report offers detailed coverage of the Global Healthcare Nanotechnology (Nanomedicine) market which includes industry chain structure, definitions, applications, and classifications. The global Healthcare Nanotechnology (Nanomedicine) market analysis is provided for the international markets including development trends, competitive landscape analysis, investment plan, business strategy, opportunity, and key regions development status. Development policies and plans are discussed as well as manufacturing processes and cost structures are also analyzed. This report also states import/export consumption, supply and demand Figures, cost, industry share, policy, price, revenue and gross margins.

It is defined as the study of controlling, manipulating and creating systems based on their atomic or molecular specifications. As stated by the US National Science and Technology Council, the essence of nanotechnology is the ability to manipulate matters at atomic, molecular and supra-molecular levels for creation of newer structures and devices. Generally, this science deals with structures sized between 1 to 100 nanometer (nm) in at least one dimension and involves in modulation and fabrication of nanomaterials and nanodevices.

Nanotechnology is becoming a crucial driving force behind innovation in medicine and healthcare, with a range of advances including nanoscale therapeutics, biosensors, implantable devices, drug delivery systems, and imaging technologies.

Market Analysis and Insights: Global Healthcare Nanotechnology (Nanomedicine) Market

The global Healthcare Nanotechnology (Nanomedicine) market size is projected to reach US$ 215130 million by 2026, from US$ 194920 million in 2020, at a CAGR of 9.6%% during 2021-2026.

Global Healthcare Nanotechnology (Nanomedicine) Scope and Market Size

Healthcare Nanotechnology (Nanomedicine) market is segmented by Type, and by Application. Players, stakeholders, and other participants in the global Healthcare Nanotechnology (Nanomedicine) market will be able to gain the upper hand as they use the report as a powerful resource. The segmental analysis focuses on revenue and forecast by Type and by Application in terms of revenue and forecast for the period 2015-2026.

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Report Scope And Segmentation Table:

Types:

Nanomedicine, Nano Medical Devices, Nano Diagnosis, Other,

Applications:

Anticancer, CNS Product, Anti-infective, Other,

Key Players:

Amgen, Teva Pharmaceuticals, Abbott, UCB, Roche, Celgene, Sanofi, Merck & Co, Biogen, Stryker, Gilead Sciences, Pfizer, 3M Company, Johnson & Johnson, SmitH& Nephew, Leadiant Biosciences, Kyowa Hakko Kirin, Takeda, Ipsen, Endo International,

CAGR 2021-2026:

9.6%

Market Size 2020:

USD 194920 million

Market Size 2026:

USD 215130 million

Historical Years:

2015-2019

Base Year:

2019

With tables and figures helping analyze worldwide Global Healthcare Nanotechnology (Nanomedicine) market growth, this research provides key statistics on the state of the industry and is a valuable source of guidance and direction for companies and individuals interested in the market.

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Healthcare Nanotechnology (Nanomedicine) Market Report Contains Following Points in TOC:

Chapter 1: Healthcare Nanotechnology (Nanomedicine) Market Product Overview, Market Segment, Size, Sales, Growth Rate, Price by Type

Chapter 2: Global Healthcare Nanotechnology (Nanomedicine) Market Competition, Sales, Price, Base Distribution, Sales Area, Product Types, and Trends by Company

Chapter 3: Healthcare Nanotechnology (Nanomedicine) Company Basic Information, Manufacturing Base and Competitors, Product Category, Applications and Specifications, Price and Gross Margin (2015-2026)

Chapter 4: Healthcare Nanotechnology (Nanomedicine) Market Status, Size, CAGR, Revenue, Price, Gross Margin and Outlook by Regions

Chapter 5: Healthcare Nanotechnology (Nanomedicine) Market Sales, and Share Segment by Application/End Users

Chapter 6: Global Healthcare Nanotechnology (Nanomedicine) Market Sales, Revenue, Growth Rate Forecast (2021-2026)

Chapter 7: Healthcare Nanotechnology (Nanomedicine) Upstream Raw Materials, Price, Key Suppliers, Cost Structure, Manufacturing Expenses, Industrial Chain Analysis

Chapter 8: Marketing Strategy Analysis, Distributors

Chapter 9: Research Findings and Conclusion

Detailed TOC of Global Healthcare Nanotechnology (Nanomedicine) Market @ https://www.industryresearch.biz/TOC/15878206

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Market is changing rapidly with the ongoing expansion of the industry. Advancement in the technology has provided todays businesses with multifaceted advantages resulting in daily economic shifts. Thus, it is very important for a company to comprehend the patterns of the market movements in order to strategize better. An efficient strategy offers the companies with a head start in planning and an edge over the competitors.Industry Research is the credible source for gaining the market reports that will provide you with the lead your business needs.

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Global Healthcare Nanotechnology (Nanomedicine) Market 2020: Key Manufacturers, Industry Share, Size, Growth Factors, Regional, and Competitive...

What is Male Menopause? Heres everything you need to know about andropause – PINKVILLA

Andropause or male menopause has to do with the declining hormonal levels in older men. Read on to know the symptoms, causes and treatment of this condition.

We often talk about how women suffer from menopause and how it affects their health. But did you know that men also experience menopause? If scientific studies are to be believed, men also go through hormonal changes after the age of 50. However, it is very different from what women go through. Male menopause is a common term used for andropause, which refers to the decline in mens testosterone levels.

In andropause, the production of testosterone and other hormones decline in men. Testosterone is a hormone that leads to changes during puberty, manages your physical and mental health, maintains muscle mass, fuels sex-drive and other important functions in the body. The condition is also known as testosterone deficiency and late-onset hypogonadism. It is often associated with hypogonadism, which shows similar symptoms to this condition.

Symptoms

As per studies, this condition can cause a variety of symptoms and complications in the body.

- low energy levels

- depression or sadness

- feeling less motivated

- not able to focus on things

- insomnia

- development of breasts

- erectile dysfunction

- infertility

- decreased libido

- reduced bone density and muscle mass

- hair loss

- hot flashes

Treatment

Your doctor might take a blood sample to test your testosterone levels. However, in most cases, the symptoms are manageable without treatment. Making healthy lifestyle choices can help you alleviate the symptoms. So, eating healthy, regular exercise, adequate sleep, and less stress are some lifestyle changes that may help.

In case youre experiencing depression, your doctor may prescribe antidepressants, therapy and above-mentioned lifestyle changes.

Male VS Female Menopause

This has been a controversial topic for several years. According to Mayo Clinic, male menopause is nothing like female menopause. Female menopause is a natural part of ageing for women, whereas, male menopause doesnt even affect some older men. Due to the significant differences between the two conditions, doctors prefer calling it andropause or late-onset hypogonadism.

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What is Male Menopause? Heres everything you need to know about andropause - PINKVILLA

Amazfit Bip S smartwatch review: Price and battery life will smoke the competition – CNET

The Amazfit Bip S isn't the best smartwatch I've ever tested -- not even close. But it's definitely the longest-running one. I wore it for almost 10 days straight without having to charge it once, and that's a lot more than I can say for its pricier competitors. But if battery life alone isn't enough to get your attention, the $69 price tag should seal the deal. (UK prices weren't available, but it's AU$119 in Australia, which is about 65.)

The Bip S is the third variant of the Amazfit Bip (along with the Amazfit Bip Lite). Created by Chinese company Huami in 2018, the original Bip was a fan favorite from the get-go. It did the basic smartwatch tasks for much less than competitors, and it lasted up to 45 days on a single charge. CNET's Scott Stein gave it high praise, calling it one of the best low-key smartwatches around.

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The Bip S has better fitness features and a slightly better screen than its predecessor, but it hasn't changed much in the last two years. And while it's still one of the best deals out there, it lags a bit behind others, like the Apple Watch or Galaxy Watch, when it comes to features and connectivity.

The Amazfit Bip S comes in four colors, with a new two-toned pink option.

Save for a few new color options (pink and green) and a brighter display, the Bip S looks like a carbon copy of the original Bip. And by that, I mean it looks like a plastic Apple Watch, with a much thicker bezel and lighter frame.

It's definitely not the most attractive smartwatch I've laid my eyes on, but it's practical and more comfortable to wear than some of the more premium, heavier watches that are bulkier. It's so light that I even forgot I had it on when I slept.

But the biggest price compromise comes at the expense of the screen. It's always on, which is a nice perk, but it's not quite as sharp, bright or responsive as a phone screen. The backlight also didn't always turn on when I needed it to. Sometimes it works on demand, but I had to exaggerate raising my wrist more often than I'd like to get it to turn on. And as mentioned before, it's not as sensitive to touch. I had to swipe or tap the screen a few times to get it to respond. When it does light up or brighten though, it's clear to see in broad daylight.

The Bip S includes a few more watch faces than its predecessors, as well as the ability to customize some of the existing ones.

The original Amazfit Bip covered the basics when it came to fitness tracking, but the Bip S takes it a step further by adding more workouts and better metrics.

It can now log up to 10 different activities including yoga, weights and swimming. Its 5ATM water resistance makes it safe for both pool and open-water swims, and its built-in GPS means you can leave your phone on dry land while you're in the water or out on a run.

Since testing the Amazfit Bip S, I've been able to track my stats accurately. But I have to remember to do it properly. For example, the dial button can be programmed as a shortcut to start workouts, which is convenient. But for running (or other outdoor workouts) I still have to press the screen to confirm GPS connection before actually registering the run. This defeats the purpose of having the shortcut in the first place. The first few times I took it out, I forgot to confirm and it didn't log my run. Because it doesn't have automatic workout detection, you have to start it manually to actually log your workouts -- yet it will pause automatically when it senses that you've stopped moving for a while.

Like its predecessor, the Bip S has continuous heart-rate monitoring. During exercises, it broke down my information into zones on the mobile app to show whether I was in a light, intensive, aerobic, anaerobic or Vo2 max (maximum oxygen consumption) heart-rate zone. This is similar to what other sports watches like Fitbit and Garmin do, but because the Bip S' results didn't always reflect the intensity at which I perceived my workout, I'm skeptical of its accuracy.

The biggest upgrades on the Amazfit Bip S are health and fitness related.

In addition to the usual steps and distance, the Bip S adds a new metric called PAI (Personal Activity Intelligence)., which grades you on how much activity you've done during the day This means that rather than relying on step count or calories burned, the Bip S uses heart rate data (along with basic demographic information) to determine whether or not the user was able to raise their heart rate long enough throughout the day to maintain a healthy lifestyle. When this is achieved, the risk of developing chronic illnesses like heart disease, hypertension and diabetes lowers, according to Huami.

The idea itself is not novel and it's similar to the move ring on the Apple Watch and zone minutes on Fitbit devices -- all of which are activity metrics that go beyond step counting. But it's new to the Bip family, and it was a good way to keep myself honest about how much activity I was doing (or not doing) during the day. Having it actually motivated me to keep going throughout the week.

The biggest deal-breaker for me about the Amazfit is that it didn't really work well as a "smart" watch. Technically it's compatible with iOS and Android, but when I tried to use it with my iPhone, the connection was unreliable. I'd stop receiving phone notifications on the watch, and I'd have to re-pair the app with the phone a few times. A firmware update did help with the connectivity issues, but it didn't completely solve the problem. Seeing my data on the phone app also took a while to sync, too.

Even when the Amazfit displayed my notifications properly, I couldn't do much with them. Because it doesn't have a microphone, dictation is also out of the question, so don't think about programming quick replies.

All in all, besides a few basic apps for the weather and music control (which is a step up from the original Bip), the watch basically mirrors your phone and doesn't have many standalone functions. Even the alarm app has to be programmed on the phone, and there are no mobile payments of any sort.

Even with its spotty connectivity and mediocre smart features, this watch keeps going long after its competitors give up. The fact that I didn't have to sideline it to a charger at the end of the day meant it never left my wrist.

Huami says it can go up to 40 days on a charge if you're doing the bare-bone functions, although realistically I'd expect about 15 days worth of battery life. Or 10 days if you're firing on all cylinders, like myself (max screen brightness and GPS workouts on a regular basis, for example).

Beyond the convenience of not having to charge it at the end of each day, having it on 24-7 meant I tracked my sleep a lot more regularly than I did with other smartwatches.

The Bip S gave me a sleep score in the morning based on a number of different factors, like sleep duration, bedtime and quality of sleep compared to other users. As a mother of two small children, I know my sleep habits have room for improvement, so I was shocked to find that I've been averaging about a 90 (out of 100) every night. So either Amazfit users have deplorable sleep habits, or it's not very good at determining whether I'm in bed nursing the baby or actually asleep. I suspect it might be a combination of both.

But even with my skepticism, having this data over a longer period of time helped me identify the times when I was getting the most restful sleep and it changed my bedtime habits (to an earlier hour) so I could maximize that deep sleep cycle. Whether it actually helps me feel more rested during the day is TBD.

If you're looking for a smartwatch to free you from your phone once in a while, this is not it. In that case you're better off getting an Apple Watch Series 3 or Galaxy Watch Active 2. The Amazfit Bip S is more in line with the Fitbit Charge, a dumb sidekick that tracks your sleep and activity levels and occasion
ally lets you know when someone is trying to reach you. But for some, that's all they really need. And for $69 it's as good of a deal on an entry-level smartwatch as you can get, especially if you're on the fence about getting one in the first place.

After this review, I'm probably going to retire the Bip S for a smarter alternative. But I'm definitely going to miss that enduring battery life. And I agree with CNET's Rick Broida, who said he might even consider going back to it when he travels to savelosing yet another cable to the hotel room power outlet. But we'll see about that once "traveling" becomes a thing again.

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Amazfit Bip S smartwatch review: Price and battery life will smoke the competition - CNET

LETTERS: Readers’ thoughts on victimless crimes, parks and voting by mail – Waco Tribune-Herald

We taxpayers work too hard for our money to see it misused and to not have a say in where it goes.

Parks are precious

Throughout the pandemic, doctors have been touting the benefits of the outdoors. As cities across Texas closed parks for the Fourth, it became painfully clear that we need our parks now more than ever.

Parks are undeniably the safest places to escape the monotony of a quarantine spent indoors. The CDC even recommends visiting parks close to your home because of the positive impact they can have on your health, both physically and emotionally.

Parks have been described as the key to reducing the burden on our health-care system. However, they are notoriously underfunded, which leads to their deterioration and decreased use.

Luckily, theres an easy solution. The Great American Outdoors Act is entering the House and would provide increased funding to better maintain our parks and make up for decades of underfunding. Congress needs to pass this act so Americans can continue reaping the benefits our parks provide.

Voting by mail

For those who believe vote-by-mail is the way to go, you might consider this: New York had an election nearly three weeks ago and theyre still counting ballots.

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LETTERS: Readers' thoughts on victimless crimes, parks and voting by mail - Waco Tribune-Herald

From Arvind Fashions to Peter England, apparel makers are betting on anti-viral fabric but they might not nece – Business Insider India

Both Arvind and Peter England have partnered with the Switzerland-based HeiQ, a leader in the textile innovation sector, to bring out the anti-viral collections. HeiQ Viroblock claims to reduce viral infectivity by 99.99% and also says it is one of the first textile technologies in the world to claim such efficacy on SARS-CoV-2.

HeiQ Viroblock is a special combination of our advanced silver and vesicle technology that has been proven effective against the human coronavirus 229E and SARS-CoV-2, causing Covid-19, with 99.99% reduction of virus in 30 minutes. It is a safe, hypoallergenic and patent pending technology, said Carlo Centonze, CEO, HeiQ Group in a statement.

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"The demand for textile with antimicrobial material has picked up in the market amidst the COVID-19 pandemic, and these are being used to manufacture N95 masks, surgical masks, PPEs and food packaging bags. While its true efficacy in the long term is yet to be proven, however, in the short and medium term this trend will certainly be relevant to the manufacturers," said Pinakiranjan Mishra, Partner and Leader, Consumer Products and Retail, EY India.

But the big brands arent the only ones to begin marketing anti-viral fabrics. Smaller companies like Nirvana Being, denim fashion brand Freakins are selling anti-viral masks.

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Meanwhile, Nirvana Being said that their masks are viral filtration efficiency (VFE) is certified and tested by Nelson Labs, USA. "We also do not have any form of coating on our masks as coatings tend to disappear after one wash. All our products were created for the mass market after thorough research wherein the team realized that COVID-19 particles have a diameter of close to 0.12 microns, and standard media and HEPA filters, which are somewhat porous, cannot filter nano-particles smaller than 0.3 microns. Therefore, Nirvana Being developed a filter using nanotechnology to filter at 0.1 micron. In short, our masks are designed to filter particles which are even smaller than COVID-19 particles with high efficiency," Jai Dhar Gupta, founder and CEO, Nirvana Being told Business Insider.

But it is important to remember that they are not proven to be effective against COVID-19 and therefore, no matter what you are wearing, you can never be too safe.

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'How do we catch hold of you' India's Supreme Court asks Vodafone Idea and that was just one of the many barbs

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From Arvind Fashions to Peter England, apparel makers are betting on anti-viral fabric but they might not nece - Business Insider India