Gdask scientist makes crucial headway in understanding killer virus by isolating COVID-19 DNA from infected patient – The First News

Dr. ukasz Rbalski (pictured) from Gdask University is the first in Poland to obtain the full genetic sequence of the SARS-CoV-2 coronavirus, isolated directly from a Polish patient. Adam Warawa/PAP

The full DNA sequence of the coronavirus virus has been taken from an infected patient after being isolated by scientists at Gdask University.

By unravelling the genetic sequence, the researchers can learn a variety of crucial information about the disease, such as how the virus deceives the human body, weakening its immune system.

A fragment of the genetic sequence of the coronavirus fully isolated by Dr. Rbalski.Adam Warawa/PAP

Other clues include COVID-19s evolutionary and geographic origins, how it found itself in Poland and how it has changed since the outbreak in China.

Team leader Dr. ukasz Rbalski at the Gdask University and Medical Academys joint Intercollegiate Faculty of Biotechnology said: Genetic material must meet many qualitative and quantitative standards in order to be decoded.

The data obtained will allow scientists from around the world to consider Poland in their research related to the epidemiology of COVID-19 disease.Public domain

In the case of viruses whose genetic material is single-stranded RNA, methods are used to multiply the amount of genetic material.

Normally, this has been done by replicating viral particles in laboratories. Nowadays, thanks to achievements in the field of molecular biology, a shorter pathway can be used without the need for virus culture.

By unravelling the genetic sequence, the researchers can learn a variety of crucial information about the disease, such as how the virus deceives the human body, weakening its immune system.Adam Warawa/PAP

The equipment used to decode coronavirus was previously used during the Ebola epidemic.

Dr. Rbalski used the latest generation of sequencers from Oxford Nanopore Technologies, which have bioinformatic protocols that limit the risk of results distortion.

Dr. Rbalskis research is published in the global GISAID database.Uniwersytet Gdaski

The GISAID database is the biggest resource of DNA sequences worldwide scientists have already uploaded over 5,000 of them and now the collection includes one from a Polish patient.

The University Clinical Centre in Gdasks Hematology Laboratory is currently carrying out further sequencing of viruses from Polish patients.

Dr. Rbalski used the latest generation of sequencers from Oxford Nanopore Technologies, which have bioinformatic protocols that limit the risk of results distortion.Adam Warawa/PAP

The next package of data will be sent to GISAID within the next few days.

The research has been published in the international GISAID database so that it can be widely used for research on vaccines and medicine for the coronavirus.

Visit link:

Gdask scientist makes crucial headway in understanding killer virus by isolating COVID-19 DNA from infected patient - The First News

Childhood Psychopathology Linked to Higher Levels of Genetic Vulnerability of Adult Depression – Clinical OMICs News

Emotional, social, and psychiatric problems in children and adolescents have been linked to higher levels of genetic vulnerability for adult depression, according to University of Queensland scientists. They made the finding Genetic Associations Between Childhood Psychopathology and Adult Depression and Associated Traits in 42998 Individuals: A Meta-Analysis, which appears inJAMA Psychiatry, while analyzing the genetic data of more than 42,000 children and adolescents from seven cohorts across five European countries.

Christel Middeldorp, MD, PhD, a child and adolescent psychiatrist at the Child Health Research Centre at the University of Queensland, said that researchers have also found a link with a higher genetic vulnerability for insomnia, neuroticism, and body mass index.

By contrast, study participants with higher genetic scores for educational attainment and emotional wellbeing were found to have reduced childhood problems, she pointed out.

We calculated a persons level of genetic vulnerability by adding up the number of risk genes they had for a specific disorder or trait, and then made adjustments based on the level of importance of each gene. We found the relationship was mostly similar across ages.

Adult mood disorders are often preceded by behavioral and emotional problems in childhood. It is yet unclear what explains the associations between childhood psychopathology and adult traits. To investigate whether genetic risk for adult mood disorders and associated traits is associated with childhood disorders, write the investigators.

This meta-analysis examined data from 7 ongoing longitudinal birth and childhood cohorts from the U.K., the Netherlands, Sweden, Norway, and Finland. Starting points of data collection ranged from July 1985 to April 2002. Participants were repeatedly assessed for childhood psychopathology from ages 6 to 17 years. Data analysis occurred from September 2017 to May 2019.

Individual polygenic scores (PGS) were constructed in children based on genome-wide association studies of adult major depression, bipolar disorder, subjective well-being, neuroticism, insomnia, educational attainment, and body mass index (BMI).

Results from this study suggest the existence of a set of genetic factors influencing a range of traits across the life span with stable associations present throughout childhood. Knowledge of underlying mechanisms may affect treatment and long-term outcomes of individuals with psychopathology.

The results indicate there are shared genetic factors that affect a range of psychiatric and related traits across a persons lifespan. Around 50 percent of children and adolescents with psychiatric problems, such as attention deficit hyper-activity disorder (ADHD), continue to experience mental disorders as adults, and are at risk of disengaging with their school community among other social and emotional problems, added Middeldorp.

Our findings are important as they suggest this continuity between childhood and adult traits is partly explained by genetic risk, she continued. Individuals at risk of being affected should be the focus of attention and targeted treatment. Although genetic vulnerability is not accurate enough at this stage to make individual predictions about how a persons symptoms will develop over time, it may become so in the future, in combination with other risk factors.

Middeldorp believes that this study and others may support precision medicine by providing targeted treatments to children at the highest risk of persistent emotional and social problems.

Read more:

Childhood Psychopathology Linked to Higher Levels of Genetic Vulnerability of Adult Depression - Clinical OMICs News

Mustang Bio Receives Advanced Therapy Medicinal Product Classification from European Medicines Agency for MB-107 Lentiviral Gene Therapy for X-Linked…

NEW YORK, April 20, 2020 (GLOBE NEWSWIRE) -- Mustang Bio, Inc. (Mustang) (MBIO), a clinical-stage biopharmaceutical company focused on translating todays medical breakthroughs in cell and gene therapies into potential cures for hematologic cancers, solid tumors and rare genetic diseases, today announced that the European Medicines Agency (EMA) has granted Advanced Therapy Medicinal Product (ATMP) classification to MB-107, Mustangs lentiviral gene therapy for the treatment of X-linked severe combined immunodeficiency (XSCID), also known as bubble boy disease. The U.S. Food and Drug Administration (FDA) previously granted Regenerative Medicine Advanced Therapy (RMAT) designation to MB-107 for the treatment of XSCID in August 2019.

EMA grants ATMP classifications to new therapeutics that are based on genes or cells and intended as long-term or permanent therapeutic solutions to acute or chronic human diseases at a genetic, cellular or tissue level. The ATMP program provides specific regulatory guidelines for preclinical development, manufacturing and product quality testing of ATMPs and offers incentives, including fee reductions for regulatory advice, recommendations and evaluation and certification of quality and non-clinical data.

Manuel Litchman, M.D., President and Chief Executive Officer of Mustang, said, We are extremely encouraged that the EMA has granted MB-107 with ATMP classification, an important step in establishing our path to market approval and commercialization in Europe. This classification complements the RMAT designation we received last year from the FDA and brings us closer to realizing our goal of commercializing MB-107 for XSCID patients, as these patients are in desperate need of innovative and potentially curative treatment options.

MB-107 is currently being assessed in two Phase 1/2 clinical trials for XSCID: the first in newly diagnosed infants under the age of two at St. Jude Childrens Research Hospital (St. Jude), UCSF Benioff Childrens Hospital in San Francisco and Seattle Childrens Hospital and the second in patients over the age of two who have received prior hematopoietic stem cell transplantation at the National Institutes of Health. Under a licensing partnership with St. Jude, Mustang intends to develop the lentiviral gene therapy for commercial use as MB-107.

About Mustang BioMustang Bio, Inc. (Mustang) is a clinical-stage biopharmaceutical company focused on translating todays medical breakthroughs in cell and gene therapies into potential cures for hematologic cancers, solid tumors and rare genetic diseases. Mustang aims to acquire rights to these technologies by licensing or otherwise acquiring an ownership interest, to fund research and development, and to outlicense or bring the technologies to market. Mustang has partnered with top medical institutions to advance the development of CAR T therapies across multiple cancers, as well as a lentiviral gene therapy for XSCID. Mustang is registered under the Securities Exchange Act of 1934, as amended, and files periodic reports with the U.S. Securities and Exchange Commission. Mustang was founded by Fortress Biotech, Inc. (FBIO). For more information, visit http://www.mustangbio.com.

ForwardLooking StatementsThis press release may contain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, each as amended. Such statements include, but are not limited to, any statements relating to our growth strategy and product development programs and any other statements that are not historical facts. Forward-looking statements are based on managements current expectations and are subject to risks and uncertainties that could negatively affect our business, operating results, financial condition and stock value. Factors that could cause actual results to differ materially from those currently anticipated include: risks relating to our growth strategy; our ability to obtain, perform under and maintain financing and strategic agreements and relationships; risks relating to the results of research and development activities; risks relating to the timing of starting and completing clinical trials; uncertainties relating to preclinical and clinical testing; our dependence on third-party suppliers; our ability to attract, integrate and retain key personnel; the early stage of products under development; our need for substantial additional funds; government regulation; patent and intellectual property matters; competition; as well as other risks described in our SEC filings. We expressly disclaim any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in our expectations or any changes in events, conditions or circumstances on which any such statement is based, except as required by law.

Story continues

Read the original here:

Mustang Bio Receives Advanced Therapy Medicinal Product Classification from European Medicines Agency for MB-107 Lentiviral Gene Therapy for X-Linked...

Ethiopia’s Ministry of Health Holds Webinar With Diaspora on COVID-19 Response at Tadias Magazine – Tadias Magazine

Ethiopia pardons more than 4,000 prisoners to help prevent coronavirus spread

Young and middle-aged people, barely sick with covid-19, are dying from strokes

By The Washington Post

Doctors sound alarm about patients in their 30s and 40s left debilitated or dead. Some didnt even know they were infected. Read more

Global coronavirus death toll surpasses 200,000, as world leaders commit to finding vaccine

By NBC News

The global coronavirus death toll surpassed 200,000 on Saturday, according to John Hopkins University data. The grim total was reached a day after presidents and prime ministers agreed to work together to develop new vaccines, tests and treatments at a virtual meeting with both the World Health Organization (WHO) and Bill & Melinda Gates Foundation. We will only halt COVID-19 through solidarity, said Dr. Tedros Adhanom Ghebreyesus, WHO Director-General. Countries, health partners, manufacturers, and the private sector must act together and ensure that the fruits of science and research can benefit everybody. As the U.S. coronavirus death tollpassed 51,000 people, according to an NBC News tally, President Donald Trump took no questions at his White House briefing on Friday, after widespread mockery for floating the idea that light, heat and disinfectants could be used to treat coronavirus patients.

Read more

Germany to start first coronavirus vaccine trial

By DW

German Health Minister Jens Spahn has announced the first clinical trials of a coronavirus vaccine. The Paul Ehrlich Institute (PEI), the regulatory authority which helps develop and authorizes vaccines in Germany, has given the go-ahead for the first clinical trial of BNT162b1, a vaccine against the SARS-CoV-2 virus. It was developed by cancer researcher and immunologist Ugur Sahin and his team at pharmaceutical company BioNTech, and is based on their prior research into cancer immunology. Sahin previously taught at the University of Mainz before becoming the CEO of BioNTech. In a joint conference call on Wednesday with researchers from the Paul Ehrlich Institute, Sahin said BNT162b1 constitutes a so-called RNA vaccine. He explained that innocuous genetic information of the SARS-CoV-2 virus is transferred into human cells with the help of lipid nanoparticles, a non-viral gene delivery system. The cells then transform this genetic information into a protein, which should stimulate the bodys immune reaction to the novel coronavrius.

Read more

Webinar on COVID-19 and Mental Health: Interview with Dr. Seble Frehywot

By Liben Eabisa | TADIAS

Dr. Seble Frehywot, an Associate Professor of Global Health & Health Policy at George Washington University in Washington, D.C. and her colleague Dr. Yianna Vovides from Georgetown University will host an online forum next week on April 30th focusing on the COVID-19 pandemic and its impact on mental health. Dr. Seble who is also the Director of Global Health Equity On-Line Learning at George Washington University told Tadias that the virtual conference titled Peoples Webinar: Addressing COVID-19 By Addressing Mental Health is open to the public and available for viewing worldwide. Read more

CDC director warns second wave of coronavirus is likely to be even more devastating

By The Washington Post

Even as states move ahead with plans to reopen their economies, the director of the Centers for Disease Control and Prevention warned Tuesday that a second wave of the novel coronavirus will be far more dire because it is likely to coincide with the start of flu season. Theres a possibility that the assault of the virus on our nation next winter will actually be even more difficult than the one we just went through, CDC Director Robert Redfield said in an interview with The Washington Post. And when Ive said this to others, they kind of put their head back, they dont understand what I meanWere going to have the flu epidemic and the coronavirus epidemic at the same time, he said. Having two simultaneous respiratory outbreaks would put unimaginable strain on the health-care system, he said. The first wave of covid-19, the disease caused by the coronavirus, has already killed more than 42,000 people across the country. It has overwhelmed hospitals and revealed gaping shortages in test kits, ventilators and protective equipment for health-care workers.

Read more

Americans at World Health Organization transmitted real-time information about coronavirus to Trump administration

By The Washington Post

More than a dozen U.S. researchers, physicians and public health experts, many of them from the Centers for Disease Control and Prevention, were working full time at the Geneva headquarters of the World Health Organization as the novel coronavirus emerged late last year and transmitted real-time information about its discovery and spread in China to the Trump administration, according to U.S. and international officials. A number of CDC staff members are regularly detailed to work at the WHO in Geneva as part of a rotation that has operated for years. Senior Trump-appointed health officials also consulted regularly at the highest levels with the WHO as the crisis unfolded, the officials said. The presence of so many U.S. officials undercuts President Trumps assertion that the WHOs failure to communicate the extent of the threat, born of a desire to protect China, is largely responsible for the rapid spread of the virus in the United States. Read more

In Ethiopia, Dire Dawa Emerges as Newest Coronavirus Hot Spot

By Africa News

The case count as of April 20 had reached 111 according to health minister Lia Tadesses update for today. Ethiopia crossed the 100 mark over the weekend. All three cases recorded over the last 24-hours were recorded in the chartered city of Dire Dawa with patients between the ages of 11 18. Two of them had travel history from Djibouti. Till date, Ethiopia has 90 patients in treatment centers. The death toll is still at three with 16 recoveries. A patient is in intensive care. Read more

COVID-19: Interview with Dr. Tsion Firew, an Ethiopian Doctor on the Frontline in NYC

Dr. Tsion Firew is Doctor of Emergency Medicine and Assistant Professor at Columbia University. She is also Special Advisor to the Ministry of Health in Ethiopia. (Courtesy photo)

By Liben Eabisa

In New York City, which has now become the global epicenter of the coronavirus pandemic, working as a medical professional means literally going to a war zone, says physician Tsion Firew, a Doctor of Emergency Medicine and Assistant Professor at Columbia University, who has just recovered from COVID-19 and returned to work a few days ago. Indeed the statistics coming out of New York are simply shocking with the state recording a sharp increase in death toll this months surpassing 10,000 and growing. According to The New York Times: The numbers brought into clearer focus the staggering toll the virus has already taken on the largest city in the United States, where deserted streets are haunted by the near-constant howl of ambulance sirens. Far more people have died in New York City, on a per-capita basis, than in Italy the hardest-hit country in Europe. At the heart of the solution both in the U.S. and around the world is more testing and adhering to social distancing rules until such time as a proper treatment and vaccine is discovered, says Dr. Tsion, who is also a Special Advisor to the Ministry of Health in Ethiopia. Dr. Tsion adds that at this moment we all as humanity have one enemy: the virus. And whats going to win the fight is solidarity. Listen to the interview

Ethiopia Opens Aid Transport Hub to Fight Covid-19

By AFP

Ethiopia and the United Nations on Tuesday opened a humanitarian transport hub at Addis Ababa airport to move supplies and aid workers across Africa to fight coronavirus. The arrangement, which relies on cargo services provided by Ethiopian Airlines, could also partially offset heavy losses Africas largest carrier is sustaining because of the pandemic. An initial shipment of 3 000 cubic metres of supplies most of it personal protective equipment for health workers will be distributed within the next week, said Steven Were Omamo, Ethiopia country director for the World Food Programme (WFP). This is a really important platform in the response to Covid-19, because what it does is it allows us to move with speed and efficiency to respond to the needs as they are unfolding, Omamo said, referring to the disease caused by the coronavirus. The Addis gateway is one of eight global humanitarian hubs set up to facilitate movement of aid to fight Covid-19, according to WFP.

Read more

Covid-19: Ethiopia to buy life insurance for health workers

By TESFA-ALEM TEKLE | AFP

The Ethiopian government is due to buy life insurance for health professionals in direct contact with Covid-19 patients. Health minister Lia Tadesse said on Tuesday that the government last week reached an agreement with the Ethiopian Insurance Corporation but did not disclose the value of the cover. The two sides are expected to sign an agreement this week to effect the insurance grant. According to the ministry, the life insurance grant is aimed at encouraging health experts who are the most vulnerable to the deadly coronavirus. Members of the Rapid Response Team will also benefit.

Read more

U.N. says Saudi deportations of Ethiopian migrants risks spreading coronavirus

By Reuters

The United Nations said on Monday that deportations of illegal migrant workers by Saudi Arabia to Ethiopia risked spreading the coronavirus and it urged Riyadh to suspend the practice for the time being.

Read more

Ethiopias capital launches door-to-door Covid-19 screening

Getty Images

By TESFA-ALEM TEKLE | AFP

Ethiopias capital, Addis Ababa is due to begin a door-to-door mass Covid-19 screening across the city, Addis Ababa city administration has announced. City deputy Mayor, Takele Uma, on Saturday told local journalists that the mass screening and testing programme will be started Monday (April 13) first in districts which are identified as potentially most vulnerable to the spread of the highly infectious coronavirus. The aggressive city-wide screening measure intends to identify Covid-19 infected patients and thereby to arrest a potential virus spread within communities. He said, the mass screening will eventually be carried out in all 117 districts, locally known as woredas, of the city, which is home to an estimated 7 million inhabitants. According to the Mayor, the door-to-door mass Covid-19 screening will be conducted by more than 1,200 retired health professionals, who responded to governments call on the retired to join the national fight against the coronavirus pandemic.

Read more

Worldwide deaths from the coronavirus hit 100,000

By The Associated Press

The worldwide death toll from the coronavirus has hit 100,000, according to the running tally kept by Johns Hopkins University. The sad milestone comes as Christians around the globe mark a Good Friday unlike any other in front of computer screens instead of in church pews. Meanwhile, some countries are tiptoeing toward reopening segments of their battered economies. Public health officials are warning people against violating the social distancing rules over Easter and allowing the virus to flare up again. Authorities are using roadblocks and other means to discourage travel.

Read more

Ethiopia COVID-19 Response Team: Interview with Mike Endale

By Liben Eabisa | TADIAS

A network of technology professionals from the Ethiopian Diaspora known as the Ethiopia COVID-19 Response Team has been assisting the Ethiopian Ministry of Health since the nations first Coronavirus case was confirmed on March 13th. The COVID-19 Response Team has since grown into an army of more than a thousand volunteers. Mike Endale, a software developer based in Washington, D.C., is the main person behind the launch of this project. Read more

Ethiopia eyes replicating Chinas successes in applying traditional medicine to contain COVID-19

By CGTN Africa

The Ethiopian government on Thursday expressed its keen interest to replicate Chinas positive experience in terms of effectively applying traditional Chinese medicine to successfully contain the spread of COVID-19 pandemic in the East African country.

This came after high-level officials from the Ethiopian Ministry of Innovation and Technology (MoIT) as well as the Ethiopian Ministry of Health (MoH) held a video conference with Traditional Chinese Medicine (TCM) practitioners and researchers on ways of applying the TCM therapy towards controlling the spread of coronavirus pandemic in the country, the MoIT disclosed in a statement issued on Thursday.

China, in particular, has agreed to provide to Ethiopia the two types of Chinese traditional medicines that the country applied to successfully treat the first two stages of the novel coronavirus, a statement from the Ethiopian Ministry of Innovation and Technology read.

Read more

WHO Director Slams Racist Comments About COVID-19 Vaccine Testing

The Director General of the World Health Organization, Dr. Tedros Adhanom Ghebreyesus, has angrily condemned recent comments made by scientists suggesting that a vaccine for COVID-19 should be tested in Africa as racist and a hangover from the colonial mentality. (Photo: WHO)

By BBC

The head of the World Health Organization (WHO) has condemned as racist the comments by two French doctors who suggested a vaccine for the coronavirus could be tested in Africa.

Africa cant and wont be a testing ground for any vaccine, said Director General Dr Tedros Adhanom Ghebreyesus.

The doctors remarks during a TV debate sparked outrage, and they were accused of treating Africans like human guinea pigs.

One of them later issued an apology.

When asked about the doctors suggestion during the WHOs coronavirus briefing, Dr Tedros became visibly angry, calling it a hangover from the colonial mentality.

It was a disgrace, appalling, to hear during the 21st Century, to hear from scientists, that kind of remark. We condemn this in the strongest terms possible, and we assure you that this will not happen, he said.

Read more

Ethiopia declares state of emergency to curb spread of COVID-19

By Reuters

Ethiopias prime minister, Abiy Ahmed, on Wednesday declared a state of emergency in the country to help curb the spread of the new coronavirus, his office said on Twitter. Considering the gravity of the #COVID19, the government of Ethiopia has enacted a State of Emergency, Abiys office said.

Ethiopia virus cases hit 52, 9-month-old baby infected

By TESFA-ALEM TEKLE | AFP

Ethiopia on Tuesday reported eight new Covid-19 cases, the highest number recorded so far in one day since the country confirmed its first virus case on March 12. Among the new patients that tested positive for the virus were a 9-month-old infant and his mother who had travelled to Dubai recently. During the past 24 hours, we have done laboratory tests for a total of 264 people and eight out of them have been diagnosed with coronavirus, raising the total confirmed number of Covid-19 patients in Ethiopia to 52, said Health Minister Dr Lia Tadese. According to the Minister, seven of the newly confirmed patients had travel histories to various countries. They have been under forced-quarantine in different designated hotels in the capital, Addis Ababa. Five of the new patients including the 9-month-old baby and the mother came from Dubai while the two others came from Thailand and the United Kingdom, she said

Read more

The coronavirus is infecting and killing black Americans at an alarmingly high rate

By The Washington Post

As the novel coronavirus sweeps across the United States, it appears to be infecting and killing black Americans at a disproportionately high rate, according to a Washington Post analysis of early data from jurisdictions across the country. The emerging stark racial disparity led the surgeon general Tuesday to acknowledge in personal terms the increased risk for African Americans amid growing demands that public-health officials release more data on the race of those who are sick, hospitalized and dying of a contagion that has killed more than 12,000 people in the United States. A Post analysis of what data is available and census demographics shows that counties that are majority-black have three times the rate of infections and almost six times the rate of deaths as counties where white residents are in the majority.

Read more

In China, Wuhans lockdown officially ends after 11 weeks

After 11 weeks or 76 days Wuhans lockdown is officially over. On Wednesday, Chinese authorities allowed residents to travel in and out of the besieged city where the coronavirus outbreak was first reported in December. Many remnants of the months-long lockdown, however, remain. Wuhans 11 million residents will be able to leave only after receiving official authorization that they are healthy and havent recently been in contact with a coronavirus patient. To do so, the Chinese government is making use of its mandatory smartphone application that, along with other government surveillance, tracks the movement and health status of every person.

Read more

U.S. hospitals facing severe shortages of equipment and staff, watchdog says

By The Washington Post

As the official U.S. death toll approached 10,000, U.S. Surgeon General Jerome M. Adams warned that this will be the hardest and saddest week of most Americans lives.

Read more

Ethio-American Tech Company PhantomALERT Offers Free App to Track & Map COVID-19 Outbreak

By Tadias Staff

PhantomALERT, a Washington D.C.-based technology company announced, that its offering a free application service to track, report and map COVID-19 outbreak hotspots in real time. In a recent letter to the DC government as well as the Ethiopian Embassy in the U.S. the Ethiopian-American owned business, which was launched in 2007, explained that over the past few days, they have redesigned their application to be a dedicated coronavirus mapping, reporting and tracking application. The letter to the Ethiopian Embassy, shared with Tadias, noted that PhantomALERTs technology will enable the Ethiopian government (and all other countries across the world) to locate symptomatic patients, provide medical assistance and alert communities of hotspots for the purpose of slowing down the spread of the Coronavirus.

Read more

2nd COVID-19 death confirmed in Ethiopia

By Dr. Lia Tadesse (Minister, Ministry of Health, Ethiopia)

It is with great sadness that I announce the second death of a patient from #COVID19 in Ethiopia. The patient was admitted on April 2nd and was under strict medical follow up in the Intensive Care Unit. My sincere condolences to the family and loved ones.

Read more

The Next Coronavirus Test Will Tell You If You Are Now Immune. And Its Fast.

People line up in their cars at the COVID-19 testing area at Roseland Community Hospital on April 3, 2020, in Chicago. (E. Jason Wambsgans / Chicago Tribune)

By Chicago Tribune

A new, different type of coronavirus test is coming that will help significantly in the fight to quell the COVID-19 pandemic, doctors and scientists say. The first so-called serology test, which detects antibodies to the virus rather than the virus itself, was given emergency approval Thursday by the U.S. Food and Drug Administration. And several more are nearly ready, said Dr. Elizabeth McNally, director of the Northwestern University Feinberg School of Medicine Center for Genetic Medicine.

Read more

Read more from the original source:

Ethiopia's Ministry of Health Holds Webinar With Diaspora on COVID-19 Response at Tadias Magazine - Tadias Magazine

Immunity and our DNA: Why women are the stronger sex – The Age

The Better Half: On the Genetic Superiority of Women is by Dr Sharon Moalem (male); a neuroscientist and evolutionary biologist. Its a fascinating, unexpected and thought-provoking argument that the simple fact of having two X chromosomes, instead of one X chromosome and one Y chromosome, is the secret to womens underappreciated success in the game of life.

Dr Sharon Moalem is a science author.

A quick refresher on chromosomes: among the 23 pairs of chromosomes X-shaped twists of DNA that are the encyclopaedia of us found in every human cell, are two sex chromosomes. In genetic females, these two sex chromosomes are both an X chromosome. In genetic males, one is an X chromosome and one is a Y chromosome.

We inherit one sex chromosome from our father and one from our mother; genetic females inherit one X sex chromosome from each parent, and genetic males inherit an X sex chromosome from the mother, and a Y sex chromosome from their father.

The X chromosome is the genetic powerhouse of the sex chromosomes, containing more than 1000 genes that orchestrate a huge number of vital cellular processes. In contrast, the Y chromosome is a stunted thing that only carries about 70 genes, most of which are involved in the production of sperm.

In genetic females, only one of their two X chromosomes is needed, so the second X chromosome is deactivated or silenced when that person is merely a bundle of cells in the uterus. The silenced X chromosome gets condensed down into a bit of cellular debris called a Barr body.

For a long time, that second, silenced X chromosome was assumed to be dead. But it turns out that second X chromosome in the cells of genetic females is actually a genetic back-up plan, helping the cell and the person to survive by throwing a genetic lifeline when things get tough. Far from being inert, about 23 per cent of those thousand or so genes on the silenced X chromosome are still active.

Dr Sharon Moalem on women having an extra X chromosome: Its like having two toolboxes. One toolbox may have a broken hammer, so you use the hammer from the second box."Credit:Getty Images

Moalem argues that this back-up set of genes gives women a significant survival advantage, as evidenced by the fact that women consistently outlive men, even in times of hardship.

Having the use of two X chromosomes makes females more genetically diverse, and the ability to rely on that diverse genetic knowledge is why females always come out on top, he writes.

This advantage is particularly evident with the immune system. Moalem recalls his time tending to HIV-positive children at an orphanage in Bangkok, and his observation that the HIV-positive boys were consistently more likely to get sick with opportunistic infections than the HIV-positive girls.

Credit:

He goes on to note that HIV-positive men are also more likely than HIV-positive women to develop tuberculosis and pneumonia, while HIV-positive women tend to have higher immune-cell counts a sign of immunological strength in the early stages of HIV infection than men do.

The X chromosome carries a large number of genes involved in immune system functioning. Moalem argues that because women have two copies of the X chromosome, they are able to produce a more diverse and effective population of immune cells than if they relied on the immune genes of only one X chromosome, as men do.

But there is a price for that more aggressive immune response; sometimes it goes overboard and starts overreacting to benign things, such as our own cells. This is the phenomenon of autoimmunity, and it disproportionally affects women.

If a microbe is the wolf, and its dressing up like Grandma, better trying to kill Grandma every once in a while than to risk being fooled by a wolf dressed like Grandma, he explains.

Having two X chromosomes also offers an unparalleled advantage if it happens that a gene on one of those chromosomes is dangerously mutated.

Loading

Say you inherit a malfunctioning gene on the X chromosome from your mother that might be associated with developmental problems. If you also have inherited an X chromosome from your father that carries a functional copy of that gene, you have a back-up, an understudy, for that faulty gene. But if you inherit a Y chromosome from your father, youre stuck with the faulty one.

This is why so-called X-linked intellectual disabilities almost entirely affect genetic males; more than 100 genes associated with intellectual disabilities have been found on the X chromosome.

Moalem also highlights a problem that numerous female authors before him have also drawn attention to: that medical science and medicine still view women as being biologically the same as men. That persistent ignorance one might even call it wilful denialism has had some devastating consequences.

Women with autoimmune conditions have long had their symptoms dismissed or trivialised by the medical establishment, which was working on the assumption that these diseases were equally prevalent in men and women.

Not that that lack of understanding has slowed females down too much. As Moalem points out, theres only one way to judge the winner in the genetic battle of the sexes: The real test of ones mettle is being able to survive the challenges of life, he writes. So, who is left standing at the end of life?

Thats right. Women.

Bianca Nogrady is the editor of The Best Australian Science Writing 2019 (NewSouth).

Visit link:

Immunity and our DNA: Why women are the stronger sex - The Age

Nobel laureate Luc Montagnier inaccurately claims that the novel coronavirus is man-made and contains genetic material from HIV – Health Feedback

CLAIM

"this coronavirus genome contained sequences of another virus [] the HIV virus (AIDS virus)"

DETAILS

Inaccurate: Genomic analyses indicate that the virus has a natural origin, and was not engineered. The so-called unique protein sequence insertions found in the 2019 novel coronavirus can be found in many other organisms, not just HIV.

KEY TAKE AWAY

Genomic analyses of the novel coronavirus show that it was not engineered. In addition, the claim that its genome contains inserted HIV sequences is based on a now-withdrawn preprint of a study that contained significant flaws in design and execution. The so-called HIV insertions identified by the authors are in fact gene sequences that can also be found in many other organisms besides HIV.

REVIEW Numerous articles published in April 2020 report that Nobel laureate Luc Montagnier claimed that SARS-CoV-2 is a manipulated virus that was accidentally released from a laboratory in Wuhan, China and that Indian researchers have already tried to publish the results of the analyses that showed that this coronavirus genome contained sequences of another virus [] the HIV virus (AIDS virus). The claim that SARS-CoV-2 contains HIV insertions began circulating in January 2020, and was propagated by outlets such as Zero Hedge and Infowars. Health Feedback covered this claim in early February 2020, and found it to be inaccurate.

Firstly, genomic analysis of the novel coronavirus, published in Nature Medicine, has demonstrated that the virus is not the product of bioengineering, but is rather of natural origin[1]. The current most likely theory, based on what scientists know about viral evolution, is that the virus first emerged in pangolins or bats (or both) and later developed the ability to infect humans. This ability to infect human cells is conferred by the so-called spike (S) protein, which is located on the surface of the enveloping membrane of SARS-CoV-2.

After the 2003-2005 SARS outbreak, researchers identified a set of key amino acids within the S protein which give SARS-CoV-1 a super-affinity for the ACE2 target receptor located on the surface of human cells[2,3]. Surprisingly, the S protein of the current SARS-CoV-2 does not contain this optimal set of amino acids[1], yet is nonetheless able to bind ACE2 with a greater affinity than SARS-CoV-1[4]. This finding suggests that SARS-CoV-2 evolved independently and undermines the claim that it was manmade[1]. Indeed, the best engineering strategy would have been to harness the known and efficient amino acid sequences already described in SARS-CoV-1 order to produce a more optimal molecular design for SARS-CoV-2. The authors of the Nature Medicine study[1] concluded that Our analyses clearly show that SARS-CoV-2 is not a laboratory construct or a purposefully manipulated virus.

Secondly, the claim that SARS-CoV-2 contains HIV insertions is based on a preprint of a research study uploaded to bioRxiv on 2 February 2020. A preprint is a study in progress that has not been peer-reviewed by other scientists. The authors of the preprint, titled Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120 and Gag, claimed to have found 4 insertions in the spike glycoprotein (S) which are unique to 2019-nCoV and are not present in other coronaviruses. The authors further asserted that all of [these inserts] have identity/similarity to amino acids residues in key structural proteins of HIV-1 [which] is unlikely to be fortuitous in nature.

The work was swiftly criticized by experts. In this Forbes article, Arinjay Banerjee, a postdoctoral fellow at McMaster University who has studied coronaviruses, said that:

The authors compared very short regions of proteins in the novel coronavirus and concluded that the small segments of proteins were similar to segments in HIV proteins. Comparing very short segments can often generate false positives and it is difficult to make these conclusions using small protein segments.

Researchers also took to Twitter to demonstrate this problem first-hand. Trevor Bedford, a faculty member at the Fred Hutchinson Cancer Research Center who studies viral evolution, re-analyzed the gene and protein sequences used by the authors and found that the so-called unique inserts appeared in many other organisms, including Cryptosporidium and Plasmodium malariae, which cause cryptosporidiosis and malaria, respectively.

Assistant professor at Stanford University Silvana Konermann also checked the authors findings and came to the same conclusion, calling the similarity spurious.

This has also been independently confirmed in another published analysis[5]. In other words, these sequences are not insertions, but are rather common sequences found in numerous other organisms such as bacteria and parasites. Therefore, the existence of these sequences in SARS-CoV-2 does not provide evidence of a link to HIV, nor that scientists purposely inserted HIV sequences into the SARS-CoV-2 genome.

In summary, genomic analysis of the virus indicates that it does not contain so-called HIV insertions and that it was not engineered in a lab. Evidence points to the virus having a natural origin.

The only thing accurate about these articles is that Nobel Prize winner and virologist Luc Montagnier did in fact make these claims. Although he holds impressive scientific credentials, his claims run contrary to credible scientific evidence. And despite having won the Nobel Prize in Physiology or Medicine in 2008 for his co-discovery of the link between HIV and AIDS, Montagnier now promotes widely discredited theories such as the pseudoscience of homeopathy and that autism is caused by bacteria that emit electromagnetic waves. Articles which repeat Montagniers claims without critically evaluating their veracity exhibit the common appeal to authority fallacy, in which something is assumed to be true simply because the person saying it is considered to be an expert, thereby misleading readers into believing that this theory is scientifically credible. This demonstrates the importance of verifying scientific claims with other experts in the same field, rather than simply taking such claims from a single expert at face value.

SCIENTISTS FEEDBACK [These comments come from an evaluation of a related claim.] Aaron T. Irving, Senior Research Fellow, Duke-NUS Medical School:Its easier to believe misinformation when it is mixed with truth. The region highlighted in the pre-print is indeed an insertion in nCoV-2019 relative to its bat ancestors and indeed it has high identity to the HIV gp120/gag. However, the authors chose to align only this small region and not do a basic check on whether there were other sequences which were also homologous (showing high degree of similarity/identity). As it turned out, the region is also homologous to many unrelated sequences. As such, the conclusions drawn from the data are no longer valid and there are many open-ended questions regarding this region highlighted. I see the authors themselves agree with this criticism by other scientists and have voluntarily withdrawn their preprint pending a much deeper investigation.

The author of this article by European Scientist also compared the genome sequences of SARS-CoV-2 and HIV using the Basic Local Alignment Search Tool (BLAST), developed by the U.S. National Institutes of Health, and found no significant similarity, explaining that In plain English, SARS-CoV-2 is not made of the bat coronavirus and small bits of the HIV virus. Readers who wish to verify the level of sequence identity between the two viruses for themselves are welcome to follow the steps listed in the article.

Read more:

Nobel laureate Luc Montagnier inaccurately claims that the novel coronavirus is man-made and contains genetic material from HIV - Health Feedback

The Very Sad Childfree Life : Strange Notions

TimeMagazine's recent cover story "The Childfree Life" has generated a good deal of controversy and commentary. The photo that graces the cover of the edition pretty much sums up the argument: a young, fit couple lounge languidly on a beach and gaze up at the camera with blissful smilesand no child anywhere in sight.

What the editors want us to accept is that this scenario is not just increasingly a fact in our country, but that it is morally acceptable as well, a lifestyle choice that some people legitimately make. Whereas in one phase of the feminist movement, "having it all" meant that a woman should be able to both pursue a career and raise a family, now it apparently means a relationship and a career without the crushing encumbrance of annoying, expensive, and demanding children.

There is no question that childlessness is on the rise in theUnited States. Our birthrate is the lowest in recorded history, surpassing even the crash in reproduction that followed the economic crash of the 1930's. We have not yet reached the drastic levels found in Europe (inItaly, for example, one in four women never give birth), but childlessness has risen in our country across all ethnic and racial groups, even those that have traditionally put a particular premium on large families.

What is behind this phenomenon? The article's author spoke to a variety of women who had decided not to have children and found a number of different reasons for their decision. Some said that they simply never experienced the desire for children; others said that their careers were so satisfying to them that they couldn't imagine taking on the responsibility of raising children; still others argued that in an era when bringing up a child costs upward of $250,000, they simply couldn't afford to have even one baby; and the comedian Margaret Cho admitted, bluntly enough, "Babies scare me more than anything." A researcher at the London School of Economics weighed in to say that there is a tight correlation between intelligence and childlessness: the smarter you are, it appears, the less likely you are to have children!

In accord with the tenor of our time, those who have opted out of the children game paint themselves, of course, as victims. They are persecuted, they say, by a culture that remains relentlessly baby-obsessed and, in the words of one of the interviewees, "oppressively family-centric." Patricia O'Laughlin, a Los Angeles-based psychotherapist, specializes in helping women cope with the crushing expectations of a society that expects them to reproduce. As an act of resistance, many childless couples have banded together for mutual support. One such group in Nashville comes together for activities such as "zip-lining, canoeing, and a monthly dinner the foodie couple in the group organizes." One of their members, Andrea Reynolds, was quoted as saying, "We can do anything we want, so why wouldn't we?"

What particularly struck me in this article was that none of the people interviewed ever moved outside of the ambit of his or her private desire. Some people, it seems, are into children, and others aren't, just as some people like baseball and others prefer football. No childless couple would insist that every couple remain childless, and they would expect the same tolerance to be accorded to them from the other side. But never, in these discussions, was reference made to values that present themselves in their sheer objectivity to the subject, values that make a demand on freedom. Rather, the individual will was consistently construed as sovereign and self-disposing.

And this represents a sea change in cultural orientation. Up until very recent times, the decision whether or not to have children would never have been simply "up to the individual." Rather, the individual choice would have been situated in the context of a whole series of values that properly condition and shape the will: family, neighborhood, society, culture, the human race, nature, and ultimately, God. We can see this so clearly in the initiation rituals of primal peoples and in the formation of young people in practically every culture on the planet until the modern period. Having children was about carrying on the family name and tradition; it was about contributing to the strength and integrity of one's society; it was about perpetuating the great adventure of the human race; it was a participation in the dynamisms of nature itself. And finally, it was about cooperating with God's desire that life flourish: "And you, be fruitful and multiply, teem on the earth and multiply in it" (Gen. 9:7).

None of this is meant to be crushing to the will, but liberating. When these great values present themselves to our freedom, we are drawn out beyond ourselves and integrated into great realities that expand us and make us more alive.

It is finally with relief and a burst of joy that we realize that our lives are not about us. Traditionally, having children was one of the primary means by which this shift in consciousness took place. That increasingly this liberation is forestalled and that people are finding themselves locked in the cold space of what they sovereignly choose, I find rather sad.Originally posted at Real Clear Religion. Used with author's permission.(Image credit: TIME Magazine)

Note: Our goal is to cultivate serious and respectful dialogue. While it's OK to disagreeeven encouraged!any snarky, offensive, or off-topic comments will be deleted. Before commenting please read the Commenting Rules and Tips. If you're having trouble commenting, read the Commenting Instructions.

Continue reading here:

The Very Sad Childfree Life : Strange Notions

I used to judge childfree women | Life and style | The …

At a friends house with a group of other mothers recently, the conversation turned to someone we all knew well: married, in her early 40s. But rather than mention her career, recent house move or the fact that shed just returned from a backpacking trip around Asia, we all exchanged looks and brought up the subject of children or lack of them.

I was as guilty as the rest of my friends: speculating on her situation, wondering if she couldnt have children or didnt want to. And if she didnt want to why not? Was she career obsessed? Did she not like them? Was she a secret drinker? Cheeks were sucked in and protective, adoring glances bestowed on the toddlers playing at our feet.

But our friend, Ive since discovered, has simply chosen not to have children. She is happy for her family to be just her husband and herself. She has never felt the urge to be a mother.

Stand-up poet and writer Kate Fox feels the same; her comedy show Good Breeding, about a child-free life, played at last years Edinburgh Festival and has been adapted for Radio 4, to be broadcast next spring. Not having children is as ingrained as my sexuality and I cant remember a time when I didnt feel it. Apparently, aged three, I announced to bemused relatives that I didnt want to have children. My mum even joked about not being maternal and said her mum wasnt either. I come from a long line of unmaternal women but my mother and grandmother had more pressure on them to procreate, she says.

To Kate, its more complex than not feeling maternal and she has experienced what she sees as every possible reason for not wanting children. Its not that I dont like kids I do but I cant imagine nurturing one all the time. I also dont think Id be able to do what I do in terms of my career and social life if I had children. Then theres the environment, but if Id really wanted children, I dont think that would have stopped me.

At 39, Kate constantly questions her decision, in case she changes her mind. I dont think I will, but I suppose Im open to persuasion. Doing my show Good Breeding was an interesting experiment in a way: I was surprised how many parents came along and how open they were about their choices. I suppose Id imagined that people who have children have always wanted them. Its not that clear cut.

So has it been an easy decision? No. It has been a long road to accept myself and believe that I am just as feminine or even emotional without being a mother.

I think my doubts have been absorbed from both my family and an attitude thats ingrained in our culture.

So why do mothers like me and my friends and many other people find it difficult to understand the choice that women such as Kate have made? The child-free have come out of the tributaries of society in the last 10 to 15 years, but the childfree choice is still not totally accepted as an equally valid choice as the choice to have children, explains Laura Carroll, author of The Baby Matrix (LiveTrue Books 2012), which examines pronatalism, the set of social and cultural beliefs that influence how we think about parenthood.

The reason boils down to pronatalist social and cultural messaging that has exalted the role of parenthood for generations. When we question pronatalist beliefs and see them for what they are beliefs we will also see that choosing not to reproduce is just as normal as the choice to reproduce.

Tap #childfree into Twitter and you could be forgiven for thinking that some sort of revolution is about to take place. Social media, as well as blogs and forums such as the site Were (not) having a baby (http://werenothavingababy.com/), the forum Childfree Living (http://childfreelivinguk.yuku.com) and Tumblrs child-free section (http://www.tumblr.com/tagged/childfree) are buzzing with discussions about what its like to live without children in a family-centric society. But Laura prefers to avoid the word movement.

While the childfree would like to see this choice accepted, I dont see a collectively organised group out there pushing for this. However, like discrimination based on race, gender, or sexual preference, there is a need for working policies to reflect equal treatment for all employees, no matter who they are or the lifestyle they choose.

Laura also believes that the media often reinforces stereotypes at the same time as giving childfree families coverage. Articles with images of a beautiful couple on a beach suggest that the childfree have all kinds of free time and disposable cash to go off on exotic holidays. This is a myth the childfree come from all walks of life.

Although the internet has allowed like-minded childfree families to connect, Laura says that sending the message that childfree is some kind of new trend is wrong. For the last decade, longer in fact, the number of women without children aged 40-44 has hovered at about one in five. And census researchers have been saying for years now that the majority of that 20% have no children by choice.

Miranda Reading, 35, a PhD student, has been married to Tony, 60, for nine years. They have decided not to have children. Neither of us has ever had the slightest desire to procreate and I think our relationship is all the better for it. As for carrying on a bloodline were happy to be in an evolutionary cul-de-sac, she says.

Miranda has, however, occasionally turned to the blogs and groups that Laura talks about. Its good to know Im not alone, a freak or abnormal in some way. I think things revolve around children a lot more than they used to. Why are museums and galleries so dedicated to childrens activities that you cant look at a painting in silence or have a proper adult-level information display? Why are childfree singles and couples discriminated against in pricing structures? And why do politicians assume women are only interested in policies that involve children? Im more interested in the economy.

I think back to the assumptions we made about our friend that afternoon, and ask Cass , 28, a childfree television administrator who recently married Andy, 27, about being on the receiving end. The main preconceptions are that we dislike children, that we are no good with children, or that we have a medical reason which means we cant have children. All of those are, of course, false I have friends who have children and I love them all dearly, and as far as I am aware I am perfectly capable of reproducing. I just choose not to, which seems to be something that society cant get its collective head around so it has to come up with excuses why I must be feeling that way.

Cass and Miranda have been refused sterilisation by the NHS because they dont have children already. Cass finds that as shes in her 20s, people expect her to change her mind. They assume that once I hit 30, or when my friends start having babies, thatll be it. I find it quite offensive. As is the idea that its not fair on all those poor women who want children and are unable to conceive.

Cass says that shes often asked what her husband thinks about it. As though my decision about my own body is anything to do with him. As it happens, he is fully supportive when we got together nine years ago he was already aware of my feelings on the matter as wed been friends before, but when the relationship got serious we had another discussion to ensure we were on the same page.

Is Andy ever quizzed about his feelings? Once people discover you dont want children, they often treat you differently. The reaction can be quite condescending, as if Im naive and making the wrong choice, he says.

I dont feel that there was a specific point when I sat down and told myself I didnt want to have children, Id just never really thought much about it when I was growing up.

Listening to childfree people talk is thought-provoking and I hope it has ensured I will never jump to the same conclusions about a woman or man who isnt a parent in future.

As a mother, its easy for me to list the things that have been hard about my chosen path the trials of motherhood seem well documented.

I asked Laura Carroll, who is 54, what has been the most difficult aspect of not having had children. When my friends started having babies, it was hard finding ways to stay in as much contact with them. But that soon passed. My friends didnt assume that because I didnt have kids I didnt know anything about children and couldnt be party to a conversation about them.

Also, they didnt lose interest in what I was up to. With many childfree women and men, when it comes to how having kids can affect friendships, its easy to get hurt and feel defensive on both sides. For those with the kids and those without, the key is to not take it personally to stay in touch with your love for your friends and your curiosity about their lives.

Miranda agrees that its important not to create a distinction between herself and friends who are parents. We all need to pull together not find reasons to divide us. Being childfree is a deliberate, often difficult choice, so dont make it harder by seeing it as a lesser one.

I admire my female friends with children I admire their dedication and hard work. Id like them to start admiring me in return. I work just as hard and am just as dedicated to my own way of life. We are all women. We should be celebrating difference, not creating barriers.

This article was amended on 11 October 2018 to remove some personal information.

More:

I used to judge childfree women | Life and style | The ...

How this working mum is coping without her village during the coronavirus pandemic – ABC News

Six months after her son Benedict was born, Skye was looking forward to getting back to work.

Needless to say, the pandemic has thrown the project manager's best-laid plans into a spin but true to form, Skye and husband Jonathan have found a unique way to manage life.

We've been following Skye's journey into motherhood since she wrote to us about her parenting fears.

Last time we spoke, the 37-year-old Sydneysider was finding her feet after "baby blues", and going into work with her husband at the family business, Benny in tow, for a sense of normalcy.

A key part of what helped make motherhood work for Skye was her "village". As for so many new mums, social distancing has taken that away.

We spoke to Skye about working and caring for Benny (now eight months old) full time, and how the pandemic has changed their life.

She's one of many people ABC Life heard from during our series on being childfree by choice. And now she's a new mum, we're checking back in.

When Skye returned to work full time earlier in the year, child care for Benny was shared between her sister-in-law, parents and a nanny.

"It was working out really well.

"I did feel a bit weird [going back to work] because it felt like starting out again."

One of Skye's fears when we spoke to her before she gave birth was falling behind in the industry.

But she's really enjoying being back.

"It's something that's for me."

She also worried about the "crushing expectations" from society for mothers to be superheros.

Losing her village with social distancing has really put that to the test.

"That was a bit rough. The sister-in-law has to stay away and I can't be with my mum and dad.

"I remember being on the phone to my mum the night before and I was about to break out in tears."

The first day of working from home with Benny, Skye says she "cracked it".

"I was doing everything the caregiving, the cleaning, the laundry. It amplified those gender-specific tasks I had been trying to avoid [when becoming a mum]."

Her and Jonathan switched up the arrangement to instead share the family business office (which is currently empty), each having half a day there, while the other cares for Benny at home, doing as much work as they can.

"It's more about time management. I do some work while Benny is asleep at night," Skye says.

Skye is enjoying Benny more than ever as he becomes more interactive.

"Looking after him is actually quite fun, he's doing more wonderful things."

And while she describes her time with him sometimes like "looking after a drunk friend", it's the bonding time she loves the most.

"When I have him in my arms, it's a feeling of 'it's not about me, it's about him'. And that is a nice feeling."

She's also really loved seeing how much happiness Benny has brought other loved ones.

"Watching Mum and Dad be grandparents is amazing, and watching Jon's sister be an aunty, that's incredible.

"I would have missed that if he wasn't around."

The coronavirus crisis and climate change have left Skye feeling anxious about Benny's future.

"I'm definitely very sad about what sort of world I'm leaving to him," she says.

"There have been moments I've felt angry or depressed."

On the upside, she's loving their time together.

"Being able to adjust working flexibility and getting this time to reconnect that is a positive.

"I'm actually enjoying the time I'm getting with the little fella, which I wouldn't have gotten without the pandemic."

Get our newsletter for the best of ABC Life each week

See original here:

How this working mum is coping without her village during the coronavirus pandemic - ABC News

Childfree: Im not having children because I want to save the planet – Stylist Magazine

I dont think we should drive ourselves to extinction by not having kids. But we could have a more integrated relationship with the earth and its other species, where we value them in their own right, rather than for resources. Its more about the belief pattern relating to our place on the earth that needs to change, rather than our actual place on the earth.

I certainly dont want my own children but if I ever decide that I do want kids in my life, I will adopt, because thats a person that is already on this earth. Its an interesting one from a demographic point of view because Im a Western white woman living in a fairly affluent area, and I have access to far more globally impacting things - such as a car - than a woman in Sudan, for example.

So if I adopted a child from a country like that, I would be taking a child who might not pollute the planet and bringing them into a situation where they could. But if I were to adopt a child in the UK, that child would probably go on to have an impact on the world anyway, and I would hope that, through my influence, they would reduce their burden on the planet as much as they could.

The rest is here:

Childfree: Im not having children because I want to save the planet - Stylist Magazine

Donald Trump set to fall back on xenophobia with re-election plan in tatters – The Guardian

Donald Trump had been intending to run a re-election campaign based on a strong economy and a socialist opponent. Both have vanished in the past month. But the US president still has his ultimate weapon: xenophobia.

Trump this week announced in a late-night tweet that he would temporarily suspend immigration into America. Two days later, when he signed an executive order, it only applied to people seeking green cards to move to the country permanently, not to temporary workers, and there were plenty of loopholes.

But by then the headlines had been written, the outrage expressed and the objective achieved: Trump was cracking down on immigration again because, he claimed, he was putting America and its workers first. The exercise was arguably less about policy than politics.

A nativist, populist message helped him win the presidency in 2016. He tried it again in the 2018 midterm elections for Congress with mixed results. Now, with his handling of a deadly pandemic under scrutiny and the economy in freefall, critics say he is ready to bet the White House on his ability to stir nationalist and racist sentiment with little subtlety.

Apart from antipathy to globalised trade, Trump is said to be a man of few core political beliefs and little ideology

This is a president who doesnt use the dog whistle of Republicans in the past, and even Democrats in the past who used dog whistle politics to talk about race in code, said Juan Cartagena, president and general counsel of Latino Justice, a civil rights organisation. This guy talks about it openly. Under normal circumstances he would have been a one-term president, but his base is pretty loyal and were still talking about a country that barely comes out in large turnout numbers.

Apart from antipathy towards globalised trade, Trump is said to be a man of few core political beliefs and little ideology. But when he descended an escalator at Trump Tower in New York in June 2015 to declare his long-shot candidacy for president, he started as he meant to go on. Mexico, he complained, was not sending its best people across the border. Theyre bringing drugs. Theyre bringing crime. Theyre rapists.

Trump also announced his signature issue: I would build a great wall, and nobody builds walls better than me, believe me, and Ill build them very inexpensively, I will build a great, great wall on our southern border. And I will have Mexico pay for that wall.

There followed an incendiary, taboo-busting election campaign in which Build that wall! became a familiar chant at Trump rallies, where he railed against the presidency of Barack Obama and threw red meat to his base. He lashed out at a judge of Mexican ancestry and a Muslim whose son died fighting for the US in Iraq. He threatened to ban Muslims from the country. He promised America first. And he won.

Two years later, campaigning on behalf of senators and representatives, Trump used rallies to stoke fears that caravans of undocumented immigrants from Guatemala, Honduras and El Salvador were set to pour into the US from Mexico. To the frustration of Republicans who wanted him to focus on economic achievements, he used vivid language to demonise criminal gangs and human traffickers and put victims families on public display.

What you will absolutely see this fall is that Donald Trump will come out and he will make up a story

This time, the strategy was only partially successful: Republicans expanded their majority in the Senate but lost 40 seats in the House of Representatives, where the new Democratic majority went on to impeach Trump.

Early in 2020, the Trump re-election campaign appeared to be built on firm foundations. There were economic talking points unemployment at its lowest for half a century, the stock market at record highs even if it did not always feel that way on the ground. Meanwhile, Senator Bernie Sanders, a democratic socialist, was leading the Democratic presidential primary race, prompting Trump and allies to warn darkly of the radical left.

These scripts have been torn up. The coronavirus pandemic has killed about 50,000 Americans and is likely to surpass US losses in the entire Vietnam war. Since the outbreak also put the economy into a coma: at least 26 million people have requested unemployment benefits, wiping out all the job gains since the great recession of 2008.

Rick Wilson, a political strategist and author of Running Against the Devil, an analysis of how the 2020 election could play out, said: The predicates of Donald Trumps campaign were fundamentally: The economy is great and I made the economy great and also, by the way, this is my great economy. Have you noticed my great economy? Thats gone. If you claim you have sole control and credit for something, then when it goes wrong, the shoe gets placed on the other foot rather quickly, and it has.

In the Democratic primary, meanwhile, Sanders quickly fell away against former vice-president Joe Biden, a moderate who served under Obama and will be much harder to caricature as a socialist menace.

Short of ammunition, his record in tatters, Trump can still fall back on the politics of division and made-for-TV partisan outrage. His daily White House coronavirus taskforce briefings have become a substitute for campaign rallies and regularly include progress reports on the border wall. The executive order on immigration, probably bearing the fingerprints of senior adviser Stephen Miller, was billed as a way to ensure that American workers take priority over foreigners in any economic recovery.

It has struck a chord with some of Trumps supporters. Douglas Collins, 86, a neurologist from Pensacola, Florida, said: Weve got to get the economy up and running, and people who live pay cheque to pay cheque and are American have to be the first consideration. Is prejudice a major factor? I dont think so.

Doug Peltier, 69, from Forest Lake, Minnesota, said: Its a valid position to be concerned about the economy and immigrants coming and taking jobs from Americans. Im not a bigot, Im not against immigrants, I have a great deal of respect for Mexicans and blacks. I do believe Americans should come first. I guess you could call me a nationalist.

Peltier, a retired school administrator who attended a Trump rally in Minneapolis last year, added: I think Trump has more support than a lot of people believe. We dont boast; we tend to be more silent. I would never put a Donald Trump sticker on my car because I know it would get keyed.

But opponents see something else: a president whose world collapsed around him, suddenly flailing in strange surroundings and grabbing on to a familiar lifeline. Wilson, the political strategist, argues that bigotry, hatred and prejudice arent a bug of the Trump program those are a feature.

He will pursue what he looks at as something that was highly effective for him in the last campaign and that is a racially and ethnically inflected campaign that tries to tell Republican voters in particular that all of their problems and concerns and issues come from the brown people.

Already Trump and Republican allies have hardened their line on China, fuelling a theory that the coronavirus might have accidentally escaped a laboratory in Wuhan and condemning the country for not raising the alarm earlier. They hope to couple this with an attack on Biden, dubbing him Beijing Biden and claiming he had a cosy relationship with China in the past.

Wilson, who is co-founder of the Lincoln Project, a political action committee aiming to prevent Trumps re-election, added: What you will absolutely see this fall is that Donald Trump will come out and he will make up a story and it will be something like, Theres boats full of diseased Chinamen coming our way, bar the door.

Democrats are braced for another bitter fight with a president who looks certain to lose the popular vote again but hopes to squeeze by in a few battleground states that decide the electoral college.

Neil Sroka, communications director for the progressive group Democracy for America, added: What we should expect in 2020 is, because of the economic implosion, because of his massive mishandling of this crisis, he will pursue a xenophobic campaign that makes the 2016 effort look like patty cake.

Here is the original post:

Donald Trump set to fall back on xenophobia with re-election plan in tatters - The Guardian

Trump says briefings ‘not worth the effort’ amid fallout from disinfectant comments – The Guardian

After more than a month of near-daily White House coronavirus press briefings, Donald Trump stayed behind closed doors on Saturday after advisers reportedly warned the president that his appearances were hurting his campaign.

Trump himself referenced his absence when he wrote on Twitter that the briefings are not worth the time & effort. The president wrote the tweet on Saturday evening, when he would usually be taking the podium to address journalists.

What is the purpose of having White House News Conferences when the Lamestream Media asks nothing but hostile questions, & then refuses to report the truth or facts accurately, he wrote. They get record ratings, & the American people get nothing but Fake News. Not worth the time & effort!

In recent weeks Trump has used the briefings to dole out unproven and debunked medical advice, suggesting that things like sunlight and an anti-malaria drug are cures to Covid-19, often causing his own medical experts to try to correct the record.

But on Friday Trump surprised observers by taking no questions and stalking out of the room after an unusually short briefing of just 22 minutes. Some took the move as an acknowledgement from Trump himself that he may have taken things too far when he said on Thursday that disinfectant could be used to cure Covid-19.

Those comments sparked shock and ridicule and warnings from healthcare experts and prompted Trump to make a ham-fisted attempt at a clawback when he later said he had made the remarks sarcastically despite video proving he had not.

While the press briefings are meant to give members of the coronavirus task force an opportunity to provide updates on the state of Covid-19 in the country, the attention around the briefings has been centered on Trumps use of the podium as his bully pulpit.

The president has used the briefings as uncensored airtime, praising his administration for its response to the crisis while criticizing the media and Democrats for any negative comeback.

Advisers close to the president told him to stop making appearances at the briefings unless special announcements needed to be made, according to multiple reports published Saturday morning. The advice comes as Trump trails Joe Biden in polls from swing states. Perhaps, his advisers believe, because his appearances are overkill.

I told him its not helping him, one adviser told Axios. Seniors are scared. And the spectacle of him fighting with the press isnt what people want to see.

Trump has reportedly been hesitant to end his briefing appearances, Axios reported, because he said they bring in good television ratings.

The president has also used the briefings as an opportunity to rile up his base in a way that would typically be done at his rallies. Trump has criticized Democrats and attacked Biden, referring to him as Sleepy Joe during briefings, veering far away from the subject of Covid-19.

It is unclear whether Trump can stay away from the podium, or whether his instincts as a reality television star will kick in and the show will go on.

Hes going to want to get media attention and control his message, Sam Nunberg, a political consultant who briefly worked on Trumps campaign in 2016, told Politico. He is the only one who thinks he can do his message best, and thats just the reality. Thats how he works.

View original post here:

Trump says briefings 'not worth the effort' amid fallout from disinfectant comments - The Guardian

In Deep review: Trump v intelligence and Obama vs the people – The Guardian

The 2016 election left the US gaping at a brewing battle between the president-elect and the most senior members of the law enforcement and intelligence communities.

Into the conflagration jumped Virgil, a pseudonymous contributor to Breitbart, who wrote of a deep state within the US government, bolstered by the mainstream media and a galaxy of contractors, profiteers, supporters, all purportedly intent on destroying Donald Trump.

His near-4,000 word essay appeared weeks before the FBI director, James Comey, briefed the president-elect about the Steele dossier, on 5 January 2017, before 11 January when Trump compared Americas intelligence agencies to Adolf Hitlers Gestapo. For Trump and his minions, Virgils take became a touchstone.

Enter the New Yorkers David Rohde. Under the subtitle The FBI, the CIA, and the Truth About Americas Deep State, the two-time Pulitzer-winner rejects the nomenclature of conspiracy theorists. In doing so he relies in part on Will Hurd, a moderate Republican congressman from Texas who served overseas with the CIA, opposed impeachment and is not seeking re-election.

Trump placing his hand on the shoulder of an FBI director and whispering into his ear is the stuff of Scorseses films

But Rohde does little to dispel the notion that government is riddled with entrenched interests, and that career officials can find themselves at odds with incumbent presidents and vice versa. In Rohdes view, civil servants are part of institutional government, a relatively benign term that masks turf fights, budget battles, policy skirmishes, built-in biases and well-formed points of view. The left has frequently derided the military industrial complex. Name-calling plays both ways.

Rohde acknowledges that all countries have permanent governments, but says the US imposes greater political control over its employees and the resultant process. Even so, campaign finance records reflect that the federal bureaucracy is not a Republican bastion.

Going back in time, in 2012 Internal Revenue Service employees donated to Barack Obama over Mitt Romney by a 41 ratio while lawyers at the National Labor Relations Board and the education department shut out Romney completely. In 2020, Joe Biden is outpacing Trump at the IRS and the justice department, as Hillary Clinton did in 2016.

Of course, who joins the federal government is not necessarily in sync with who prevails on election day. But the Trump presidency appears unique and disheartening. The fight between the president and law enforcement and intelligence was an avoidable consequence of Russias active measures in support of the Trump campaign, and a candidate all too willing to accept the sordid bounty.

I love WikiLeaks was bound to gain attention. And as Rohde makes clear, Trump has waged a persistent assault upon the rule of law, the ideal of a justice department removed from politics and the concept of an intelligence community loyal to the country rather than the man in the Oval Office.

A recent Senate intelligence committee report observed that the intelligence community has present[ed] a coherent and well-constructed intelligence basis for the case of unprecedented Russian interference in the 2016 US presidential election. As Robert Mueller reminded us, absence of indictment was not akin to prosecutorial absolution, despite what the attorney general, William Barr, may have thought and said.

On that score, in an opinion issued last month Reggie Walton, a George W Bush appointee to the federal bench, seriously questioned Barrs integrity and credibility, using words like distorted and misleading to drive the point home.

Suffice to say, all this is coming with a steep cost to our democracy and our post-Watergate system, which sought to make law enforcement something other than the handmaiden of the White House. Trump placing his hand on the shoulder of an FBI director and whispering into his ear is the stuff of Martin Scorseses films. Lock her up is chant befitting a democracy in decay or worse.

In Deep also pays attention to the Trump administrations privatization of foreign policy

Rohde, however, reminds us that Trumps predecessor was by no means angelic when it came to encroachment on civil liberties, despite stints on the Harvard Law Review and as a professor of constitutional law at the University of Chicago. Under Obama the Pentagon regarded leaking non-classified information as tantamount to aiding the enemies of the United States.

Rohde recalls how the intelligence community under Obama spied on a Senate committee, misled Congress about spying on Americans and expanded the use of drone warfare. He offers granular detail on how James Clapper, Obamas director of national intelligence, obfuscated before the Senate intelligence committee on data collection and surveillance of US citizens.

Years later, Clapper would accuse Trump and his administration of an assault on truth and posit that Trump might be a witting or unwitting Russian asset. Regardless of the validity of the charges, Rohde voices discomfort with intelligence community alumni playing an outsized role in clashes with the administration.

In Deep also pays attention to the Trump administrations privatization of foreign policy. Among other things, Rohde describes at length how the efforts in Ukraine of Trumps personal lawyer, Rudy Giuliani, helped lead to Trumps impeachment. Not surprisingly, Republican stalwarts have failed to thunder paroxysms of outrage over this dubious practice as they do over the supposed deep state.

As Rohde repeatedly reminds us, negative partisanship increasingly drives our politics. With social chasms underlying most of the divide, dont expect it to disappear anytime soon. In our cold civil war, elections have morphed into safety valves and battlefields. Wisconsins potentially lethal conflict over mail-in ballots is just the latest reminder.

In assessing the existence of a deep state, or otherwise, it is worth remembering what Steve Bannon had to say about it the same Steve Bannon who skippered Trumps upset victory and signed Virgils paycheck back in his Breitbart days. As Bannon admitted to James Stewart of the New York Times, the deep state conspiracy theory is for nut cases, because America isnt Turkey or Egypt.

True enough, but our freedom and trust continue to erode with no end in sight.

Original post:

In Deep review: Trump v intelligence and Obama vs the people - The Guardian

Trump attack on Biden highlights president’s own past dealings with China – The Guardian

Donald Trump has a share in a New York property development that borrowed tens of millions of dollars from China, it was reported on Friday.

The debt derived from a 30% share the US president owns in a billion-dollar building on the Avenue of the Americas in Manhattan, which was refinanced in 2012 with $211m of the funding coming from the state-owned Bank of China, Politico reported on Friday.

However, the Bank of China said it had sold the loan in the commercial mortgage-backed securities (CMBS) market less than a month after the loan was made, and so Trump was not even indirectly indebted to the bank.

But the Trump Organisations far-flung real estate business has involved dealings with Chinese state-owned firms on several occasions, complicating Trumps emerging election strategy of portraying his Democratic opponent, Joe Biden, as being soft on China. In a briefing on Saturday, Trump said that China will own the United States if Biden was elected in November.

But among the known Trump Organisation business dealings with Beijing, a Chinese state-owned construction company is helping build the Trump World Golf Club in Dubai, and Beijing has awarded trademarks to the presidents daughter, Ivanka. In the past, Ivankas husband (and a White House adviser), Jared Kushner, has sought Chinese finance for at least one major real estate deal.

The president is a passive minority investor in the 1290 Avenue of the Americas office tower which received the Bank of China funding in 2012. The main investor is Vornado Realty Trust, which owns 70%.

A Bank of China spokesperson said: On November 7, 2012 several financial institutions including the Bank of China participated in a commercial mortgage loan of $950 million to Vornado Realty Trust. Within 22 days, the loan was securitized and sold into the CMBS market, as is a common practice in the industry. Bank of China has not had any ownership interest in that loan since late November 2012.

Neither the White House nor the Trump Organization responded to requests for comment. Trump has officially handed over the day-to-day running of his business empire to his sons, but he benefits financially from its profits, producing multiple conflicts of interest. The Trump Organization has recently applied for coronavirus compensation from the government.

Trumps approach to China has alternated between combative and unctuous, particularly in relation to the Chinese president, Xi Jinping, with whom Trump has consistently claimed to have an excellent personal relationship.

Trump tweeted on 24 January, in the early stages of the pandemic: China has been working very hard to contain the Coronavirus. The United States greatly appreciates their efforts and transparency. It will all work out well. In particular, on behalf of the American People, I want to thank President Xi!

This article was amended on 25 April 2020 to include a response from representatives of the Bank of China concerning the 2012 loan. The original headline, which wrongly suggested Donald Trump had a current debt with the bank, was also amended.

Read the original:

Trump attack on Biden highlights president's own past dealings with China - The Guardian

The Luxury of Irresponsibility – New York Magazine

President Donald Trump. Photo: Drew Angerer/Getty Images

On Thursday, President Trump wondered aloud if blasting peoples insides with ultraviolet light and injecting their lungs with disinfectant might be a more effective way to slow the coronavirus than the measures currently in use. It was one of the more irresponsible things hes said in a presidency defined by its irresponsibility. He was able to say this, without fear of how guileless Americans might act on his suggestion, because he recognizes that responsibility is only required of people who cant afford to evade it, and he is not one of those people.

Heres the quote:

So supposing we hit the body with a tremendous, whether its ultraviolet or just very powerful, light and I think you said that hasnt been checked but youre going to test it and then I said suppose you brought the light inside the body, which you can do either through the skin or in some other way. And I think you said youre going to test that, too. Sounds interesting.

Then I see the disinfectant where it knocks it out in a minute, one minute. Is there a way we can do something like that by injection inside? Or almost a cleaning, cause you see it gets in the lungs and it does a tremendous number on the lungs. So itd be interesting to check that. So youre going to have to use medical doctors but it sounds interesting to me, so well see but the whole concept of the light. The way it kills it in one minute, thats pretty powerful.

Flooding ones body with disinfectant and UV rays is an effective coronavirus remedy in much the same way that getting cancer and dying is which, incidentally, is among the risks of doing what Trump suggested. Interpreted generously, the president was not saying that people should do this at home, but enough medical experts, elected officials, and manufacturers of household cleaning products seem to have heard about the Arizona man who died after self-administering a chemical touted by Trump as a cure to dissuade Americans from it anyway. Trumps pandemic response team, meanwhile, was left to the unenviable task of pretending, or intending, to take his musings seriously and assent to follow-up research, knowing full well that they have better things to do. A familiar chorus of Trump stalwarts in conservative media set about recasting his suggestion as, alternately, essentially benign or willfully misinterpreted by liberals too blinded by their hatred of the president to recognize his epidemiological brilliance.

One of the more striking features of the American response to the coronavirus pandemic has been the inverse relationship between whos expected to practice the most individual responsibility and whos doing the most damage by exhibiting none. We each have a role to play in stemming COVIDs spread; personal decisions such as washing ones hands, practicing social distancing, and using personal protective equipment, whenever possible, are three simple things that all but the most deprived Americans and essential workers can do to help. Yet more often, its the people least equipped to protect themselves who are most readily left to their own devices poor people, prisoners and when misfortune befalls them, either tacitly or explicitly blamed for its occurrence. This is how centuries of structural deprivation can besiege black and Latino Americans,including outsize exposure to toxins and pollutants and sparse access to healthy food and medical care,and still, once these same communities start to see COVIDs highest death rates and costliest economic fallout, the sober response given by the federal government points to their purported irresponsibility, namely alcohol, tobacco, and drug use: We need you to understand especially in communities of color, we need you to step up and help stop the spread so that we can protect those who are most vulnerable, said U.S. surgeon general Jerome Adams, who is black, at a press conference earlier this month.

The incongruity of Adamss remarks has a few possible explanations. On the one hand, he did acknowledge that the burden of social ills fuels these disparities, though he wasnt explicit about what he meant. On the other, Adamss calls for black and brown people to step up implies that they were doing less than was standard to begin with, on top of being the only directed statement on the matter to come out of an administration whose conduct and rhetoric dont just routinely blame nonwhite people for the struggles they face, but for white peoples problems as well. In Trumps view, black people wallow in urban hellscapes kept in squalor by a mix of their own innate filth and the machinations of corrupt black leaders; Latino immigrants, shaped by the shithole countries in which they were spawned, represent a scourge of job theft, sexual predation, disease, and drug-related crime. Both are major contributors to the disaster that Trump has claimed the United States was without him leading it, the reason why it was no longer the great country it had been. Even if Adams has a more nuanced view of the matter, the administration whose orders he follows has had little of substance to contribute to fixing the issues of racial and class inequality that the pandemic has brought to the fore.

The reality, as practiced, looks more like old hat: a stated desire for more personal responsibility, invoked as an excuse to avoid fixing structural problems. This is a longstanding feature of American political life, and has always been racialized; black joblessness rates, use of public assistance, crime in black communities, the black-white education gap all have been attributed, at one point or another, by conservatives and liberals and black and white Americans alike, to pathologies that are either genetically inborn or otherwise culturally unique to black people. Pointing to these supposed pathologies has been enough to turn swathes of Americans against investment in improving black lives. Black-on-black crime is the canard invoked most commonly to justify unchecked police brutality and staggering incarcerations rates; research has demonstrated that white opposition to welfare policies in recent years is driven in large part by their feeling that economic mobility is a racial zero-sum game, whereby improved prospects for nonwhites mean worse ones for them.

But responsibility evaporates at the top. I do not take responsibility at all, Trump said in March, at a press conference where he was asked about the United States lack of coronavirus testing capacity. This statement, dazzling in its clarity, could describe his own attitude toward governing, where nothing is his fault and he feels personally responsible for nobodys well-being but his own, as well as that of his party, whose zeal for funneling billions of dollars into corporate coffers and the pockets of the rich define its tax policy and pandemic bailouts alike. The GOP, more than any other political entity, has been the most strident proponent of the need for more personal responsibility in the U.S. But when confronted by a president whose literal job is to be responsible and take responsibility, but who couldnt be less interested in either, they have dutifully advanced his policy agenda, defended his behavior and pandemic response, and dismissed concerns about his unhinged and often dangerous behavior, which now includes rambling glowingly about the public health merits of injecting a human being with disinfectant, as partisan bias. (Trump has since said his remarks were a prank to goad the media.)

Trump will not stop, will not become responsible or take responsibility, because he has no incentive to, and Trump only responds to incentives, specifically those that enrich and empower him. Conversely, in recent decades, countless joules of political energy have been expended bemoaning supposed irresponsibility in communities wracked by institutional neglect. Conservatives, some liberals, and Republicans in particular have staked their moral cachet on demanding an answer to when, at long last, Americas losers and layabouts will finally take responsibility for the circumstances theyre responsible for. The coronavirus pandemic is a timely reminder of what theyve been more consistently willing to settle for: one of their own, standing astride the suffering of millions, and proudly exclaiming, Not I.

Daily news about the politics, business, and technology shaping our world.

Read more from the original source:

The Luxury of Irresponsibility - New York Magazine

Hillary Clinton: ‘Please don’t poison yourself because Donald Trump thinks it could be a good idea’ | TheHill – The Hill

Hillary ClintonHillary Diane Rodham ClintonThe Memo: Bully pulpit may be backfiring for Trump Poll: Trump has 5-point lead over Biden in Texas China emerges as new flashpoint in 2020 campaign MORE on Friday knocked President TrumpDonald John TrumpWH officials discuss HHS secretary replacement following criticism of pandemic response: WSJ Pentagon leaders at impasse about next steps for Capt. Brett Crozier: report Trump forgoes WH press briefing for the first time since Easter weekend MOREs controversial comments about disinfectant possibly being used to treat coronavirus patients, warning people not to poison themselves based on the presidents statement.

Please dont poison yourself because Donald Trump thinks it could be a good idea, the former secretary of State wrote on Twitter.

Please dont poison yourself because Donald Trump thinks it could be a good idea.

The dig from the 2016 Democratic presidential nominee comes as Trump faces criticism from medical professionals for his remarks.

During a White House briefing on Thursday, Trump suggested medical experts shouldstudy exposing the human body to heat and light as a treatment for coronavirus. He also asked if there was a way to use disinfectants on the body "by injection inside or almost a cleaning."

"Maybe you can, maybe you cant ... Im not a doctor. But Im, like, a person that has a good you-know-what," Trump said, pointing to his head.

The presidents comments triggered Lysol manufacturer Reckitt Benckiserto issue a rare statement that under no circumstance should its products be administered into the human body or be used as a treatment for the coronavirus.

The company, which also sells Dettol in the United Kingdom, sharedin a statement on its websitethat due to recent speculation and social media activity, they had been asked whether internal administration of disinfectants may be appropriate for investigation or use as a treatment for coronavirus.

As a global leader in health and hygiene products, we must be clear that under no circumstance should our disinfectant products be administered into the human body (through injection, ingestion or any other route). As with all products, our disinfectant and hygiene products should only be used as intended and in line with usage guidelines. Please read the label and safety information, the company said Friday.

The hashtag #DontDrinkBleach began trending across the United States on Friday afternoon as Twitter users reacted to Trumps comments.

Watching Trumps Press Conferences be like #lysol #disinfectant #DontDrinkBleach pic.twitter.com/36YpRLcPdR

Remember that skit on SNL. This one? Yeah! They warned us too- but we chuckled. #DontDrinkBleach pic.twitter.com/ypcFrSoIzN

The look on Dr. Birx face as Trump talks injecting a #disinfectant and "light and heat" to kill the coronavirus is the look people have when an insane person gets on the NYC subway and launches into a conspiracy laden rant. #DontDrinkBleach #Lysol https://t.co/ptoUq1QPlk

View original post here:

Hillary Clinton: 'Please don't poison yourself because Donald Trump thinks it could be a good idea' | TheHill - The Hill

Season finale: Is this the end of the Trump show? – RTE.ie

Throughout these weeks of lockdown I'm sure most of us have been binge-watching Netflix, box sets and various mini-series.

My current TV addiction starts every evening at around 6pm and a single episode can run for up to two hours.

It's full of drama, conflict and plot twists. It's Donald Trump's daily media briefing.

I may soon have to find a new series however, amid reports that this hit TV show could be axed.

Not long after taking office in 2017, the Trump administration abandoned traditional press conferences.

Under previous presidents, the White House Press Secretary would give daily, on-camera updates to the media, with even POTUS himself making appearances in the briefing room.

Donald Trump changed all that.No more formal briefings but lots of impromptu 'press gaggles', where the president stops and talks to journalists on his way to or from engagements.

Often times this would take place in the White House South Lawn before MrTrump boarded his chopper, Marine One.

This had its advantages.The 'gaggle'would sometimes last for up to 40 minutes with the president taking questions from all the journalists present.

There were also major disadvantages.At times of controversy Mr Trump could ignore questions, claiming not to be able to hear over the roar of the helicopter, or he could just skip the entire thing altogether and walk past the journalists with a wave.

The White House would dismiss criticism over the lack of press briefings by pointing to these regular gaggles as evidence of a transparent, accessible presidency.

Mr Trump, who had rarely darkened the door of the James S Brady Briefing Room, began making nightly appearances at the podium when the coronavirus outbreak began.

At the start, the president would give Covid-19 updates but the press conferences quickly evolved into something else.

In the absence of any public gatherings because of the lockdown, Mr Trump has frequently used his daily briefings as campaign rallies.

He promotes his own handling of the crisis and has even played campaign-style videos inside the briefing room.

As the president frequently points out, his appearances are getting big TV ratings and this has given hima major advantage over his rival Joe Biden who has no such platform.

Early in the coronavirus crisis, MrTrump saw an increase in his approval ratings and a majority of Americans were happy with his handlingof the outbreak.

In recent weeks however, his poll numbers have slipped and Joe Biden is predicted to beat him in many key states.

The power of the press briefing has waned and the president has no one to blame but himself.

On some days, there hasn't been any new coronavirus information to provide but the media conferences have been held anyway just to give Mr Trump some prime-time TV coverage.

In the absence of updates on the virus, he frequently goes off script and embarks on ramblingrants.

He attacks journalists, governors and Democrats.

He also offers his own views on treatments and cures, something which has led to controversy.

On Thursday night, he asked his scientists to explore if heat, light and disinfectants could be applied to the human body to treat the virus.

It led to an outcry with medical experts urging people to ignore Mr Trump and it even prompted the company that makes Dettol to issue a statement warning the public not to inject its products.

Donald Trump claimed he was being sarcastic and blamed the "fake news media" but the damage was done.

Would this mark the end of the daily press briefing?Would this be the moment that the TV execs decided not to commission a second season?

The news website Axios has reported that the White House is planning to scale back the media conferences with fewer and shorter appearances by the president.

According to the article, Mr Trump's advisers have told him the briefings are hurting his poll numbers, and "the spectacle of him fighting with the press isn't what people want to see".

If the briefings are to be wound down in the coming days, no doubt there is still plenty of drama and plot twists to come.

Every TV show goes out with a bang and who knows what this season finale will have in store.

Read the original post:

Season finale: Is this the end of the Trump show? - RTE.ie

Revealed: leader of group peddling bleach as coronavirus ‘cure’ wrote to Trump this week – The Guardian

The leader of the most prominent group in the US peddling potentially lethal industrial bleach as a miracle cure for coronavirus wrote to Donald Trump at the White House this week.

In his letter, Mark Grenon told Trump that chlorine dioxide a powerful bleach used in industrial processes such as textile manufacturing that can have fatal side-effects when drunk is a wonderful detox that can kill 99% of the pathogens in the body. He added that it can rid the body of Covid-19.

A few days after Grenon dispatched his letter, Trump went on national TV at his daily coronavirus briefing at the White House on Thursday and promoted the idea that disinfectant could be used as a treatment for the virus. To the astonishment of medical experts, the US president said that disinfectant knocks it out in a minute. One minute!

He went on to say: Is there a way we can do something, by an injection inside or almost a cleaning? Because you see it gets in the lungs and it does a tremendous number on the lungs, so itd be interesting to check that.

Trump did not specify where the idea of using disinfectant as a possible remedy for Covid-19 came from, and the source for his notion remains obscure. But the Guardian has learned that peddlers of chlorine dioxide industrial bleach have been making direct approaches to the White House in recent days.

Grenon styles himself as archbishop of Genesis II a Florida-based outfit that claims to be a church but which in fact is the largest producer and distributor of chlorine dioxide bleach as a miracle cure in the US. He brands the chemical as MMS, miracle mineral solution, and claims fraudulently that it can cure 99% of all illnesses including cancer, malaria, HIV/Aids as well as autism.

Since the start of the pandemic, Genesis II has been marketing MMS as a cure to coronavirus. It advises users, including children, to mix three to six drops of bleach in water and drink it.

In his weekly televised radio show, posted online on Sunday, Grenon read out the letter he wrote to Trump. He said it began: Dear Mr President, I am praying you read this letter and intervene.

Grenon said that 30 of his supporters have also written in the past few days to Trump at the White House urging him to take action to protect Genesis II in its bleach-peddling activities which they claim can cure coronavirus.

On Friday, hours after Trump talked about disinfectant on live TV, Grenon went further in a post on his Facebook page. He claimed that MMS had actually been sent to the White House. He wrote: Trump has got the MMS and all the info!!! Things are happening folks! Lord help others to see the Truth!

Paradoxically, Trumps outburst about the possible value of an injection of disinfectant into the lungs of Covid-19 sufferers came just days after a leading agency within the presidents own administration took action to shut down the peddling of bleach as a coronavirus cure around the US.

Last week the US Food and Drug Administration obtained a federal court order barring Genesis II from selling what was described as an unproven and potentially harmful treatment for Covid-19. The FDA also ordered a disciple of Genesis II, Kerri Rivera, to remove claims that MMS cured coronavirus from her website.

Last August the FDA issued an urgent warning urging Americans not to buy or drink MMS, which it said was a dangerous bleach which has caused serious and potentially life-threatening side effects. Drinking MMS can cause nausea, diarrhea and severe dehydration that can lead to death, the federal agency said.

The Guardian contacted the White House asking whether Grenons letter had influenced Trumps comments on disinfectant, but did not immediately receive a response.

Another advocate of bleach as a miracle cure who has been seeking to interest Trump in the treatment is Alan Keyes. He is a former ambassador and adviser to Ronald Reagan who ran unsuccessfully as a Republican candidate for the US Senate and on three occasions for the US presidency.

Keyes has featured Genesis II bleach products as a miracle cure on his online conservative TV show, Lets Talk America.

It is not known whether Keyes has discussed MMS with Trump. But the two men have overlapping interests.

Not only have they both featured in Republican party and presidential politics, but they were both leading proponents of the Birther conspiracy theory that wrongfully suggested Barack Obama was born outside America.

Keyess TV show is hosted on IAMtv, a rightwing web-based channel. IAMtvs other leading anchor is Bob Sisson, who has also advertised Genesis II bleach products on air.

In one of his shows, first reported by the Daily Beast, Sisson held up two bottles of Genesis II MMS and said: Gonna meet Trump, its only a matter of time. President Trumps gonna invite us up there, when he finds out about this stuff.

On Friday Trump claimed he was being sarcastic in his remarks but there is no evidence to back up that claim and he appeared entirely serious as he made them.

Read more:

Revealed: leader of group peddling bleach as coronavirus 'cure' wrote to Trump this week - The Guardian

Trump and Putin issue rare joint statement promoting cooperation – Reuters

WASHINGTON (Reuters) - U.S. President Donald Trump and his Russian counterpart Vladimir Putin issued a rare joint statement on Saturday commemorating a 1945 World War Two link-up of U.S. and Soviet troops on their way to defeat Nazi Germany as an example of how their countries can cooperate.

FILE PHOTO: Russia's President Vladimir Putin and U.S. President Donald Trump shake hands during a bilateral meeting at the G20 leaders summit in Osaka, Japan, June 28, 2019. REUTERS/Kevin Lamarque

The statement by Trump and Putin comes amid deep strains in U.S.-Russian ties over a raft of issues, from arms control and Russias intervention in Ukraine and Syria to U.S. charges that Russia has spread disinformation about the novel coronavirus pandemic and interfered in U.S. election campaigns.

The Wall Street Journal reported that the decision to issue the statement sparked debate within the Trump administration, with some officials worried it could undercut stern U.S. messages to Moscow.

The joint statement marked the anniversary of the April 25, 1945 meeting on a bridge over the Elbe River in Germany of Soviet soldiers advancing from the east and American troops moving from the West.

This event heralded the decisive defeat of the Nazi regime, the statement said. The Spirit of the Elbe is an example of how our countries can put aside differences, build trust, and cooperate in pursuit of a greater cause.

The Journal said the last joint statement marking the Elbe River bridge link-up was issued in 2010, when the Obama administration was seeking improved relations with Moscow.

Trump had hoped to travel to Moscow to mark the anniversary. He has beencomplimentary of Putin, promoted cooperation with Moscow, and said he believed the Russian leaders denials of Russian interference in the 2016 U.S. presidential election.

Senior administration officials and lawmakers, in contrast, have been fiercely critical of Russia, with relations between the nuclear-armed nations at their lowest point since the end of the Cold War.

The Republican-led Senate Intelligence Committee on Tuesday issued a bipartisan report concurring with a 2017 U.S. intelligence assessment that Russia pursued an influence campaign of misinformation and cyber hacking aimed at swinging the vote to Trump over his Democratic rival, Hillary Clinton.

U.S. intelligence officials have warned lawmakers that Moscow is meddling in the 2020 presidential election campaign, which Russia denies.

Reporting by Jonathan Landay; Additional reporting by Steve Holland, editing by Ross Colvin and Chizu Nomiyama

Go here to read the rest:

Trump and Putin issue rare joint statement promoting cooperation - Reuters

Donald Trump Keeps Trying to Make Reality Disappear – The Daily Beast

Donald Trumps conduct in a week when Wednesdays record number of coronavirus deaths doubled next day to a new record of 4,591 can only be understood if you realize that the president is not a 73-year-old man with the experience and maturity that suggests. Trump is actually a 10-year-old having aged in reverse dog years. He has the crimped emotions and empathy of a deluded superhero (only I can fix it), the limitations of a C-student, and the work ethic of a pre-teen who resents any challenge to his fragile ego and responds positively only to praise. All he does now is try to make to reality disappear.

Seeing Trump as a captive of his immaturity is a way to anticipate and perhaps defend against his dangerous behavior that is getting worse as the stakes get higher. A know-it-all, hes opening the countrys parks, gyms, and restaurants not just against the advice of experts and the views of 80 percent of the country, but of usual sycophants like Sen. Lindsey Graham and a long list of CEOs, who constituted the highest IQ on a call ever but who for all their smarts, found their names read off without their permission. If you took a drink every time Trump called them and red state governors people who love our country as opposed to Democrats, whom he calls half-wits and whiners, youd be intoxicated by 7 p.m.

Trump requires close supervision, strict limits on his screen time, and guidance on how to tell real doctors from single-named celebrity ones like Dr. Oz.

To advance his plan, Trump cited large areas where the virus has been totally eradicated to justify premature emancipation. Is the large area hes referring to called Mars? Or is it South Dakota, one of those 29 states ready to open any moment, yet with a spot so hot the Smithfield plant in Sioux Falls had to close after 777 workers tested positive?

Thats tragic for those who consider bacon one of the four major food groups, and for Trumps argument. If a part of the country isnt infected, just give it a few days without social distancing and it will be. If an area is opened before it should be, wait a few days, and it will be reinfected. If Trump did his homework, hed know that after the Rev. Jerry Falwell, who acted to stop Democrats from harming the presidents economy, called students back to Liberty University, he saw the town hit by 78 new cases.

Parental guidance is advised. Trump requires close supervision, strict limits on his screen time, and guidance on how to tell real doctors from single-named celebrity ones like Dr. Oz, who told Trumps good buddy Sean Hannity that a mortality rate of 2 to 3 percent is an appetizing trade-off for jump-starting the economy. He needs a constant reminder that car accidents and smoking arent contagious.

Hes right about one thing: We cant believe the job hes done.

And how about getting Trump to put in a days work on a matter of life and death? Until D.C. Mayor Muriel Bowsers mid-March stay-at-home directive confined him to the White House,Trump spent much of the crisis at rallies and golfing. Hes home (mostly alone) now but still needs to spend less time in front of the TV, which only generates ill-advised tweet storms, and attend a meeting or two of his task force in the Situation Room, where the seating chart changes daily depending on who up and whos down in the presidents clique.

If Trump had anyone on staff not afraid of his cruel temper, he might have fixed his testing problem before the press noticed that his Power-Point presentation passing as a plan did nothing to increase that essential step in the process. While hes taken credit for tests that are the envy of the world and sniffed that hes president, not a guy clutching swabs in a parking lot 2,000 miles away, hes still stuck on his March 6 lie that anybody who wants to get a test can get a test and that Barack Obama didnt leave him one when the virus didnt exist back then.

At a rate of 3 million tests in three months, a majority of the country would be tested in six years. Cornered, Trump turned to Dr. Deborah Birx. After a word salad shes as famous for as for her scarves didnt fool anyone, Trump took his ball and left, clocking his shortest briefing ever on Thursday.

That didnt end the criticism. The next morning he was assailed by his arch-nemesis Gov. Andrew Cuomo, whos held his fire the last couple of weeks to move from the ungrateful ledger to the grateful one to wheedle ventilators out of the national stockpile Jared Kusher thought was his. Cuomo pleaded that a national problem required a national strategy and federal funds. Why dont you show as much consideration to your states as you did to your big businesses and your airlines? he asked. What am I supposed to do, send a bouquet of flowers?

Trump still has a childlike belief he can spin the virus, putting 60,000 deaths on the house, having chosen a model that predicted 2.2 million fatalities if he did nothing and by that faulty reasoning, congratulating himself for a job so well done no one can believe it.

What no one can believe, except the hardest core of his base, is that a con man in a gimme cap and a superhero cape clings to the notion he alone can fix everything, including a broken Dow Jones, and get us all to Splash Mountain at Disneyland without testing Mickey. Hes right about one thing: We cant believe the job hes done. On top of all the deaths that wouldnt have happened if thered been an adult in the White House, its too much to take in.

Read the original here:

Donald Trump Keeps Trying to Make Reality Disappear - The Daily Beast