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NASA had a record pool of 18000 applicants to be an astronaut. These 12 made it. – USA TODAY

Posted on June 8, 2017 by Danzig

NASA chose 12 new astronauts Wednesday from its biggest pool of applicants ever, selecting seven men and five women who could one day fly aboard the nation's next generation of spacecraft. (June 8) AP

In this photo obtained from NASA, the 2017 NASA astronaut candidates stop to take a group photo while getting fitted for flight suits at Ellington Field near NASAs Johnson Space Center in Houston, Texas, on June 7, 2017.(Photo: HO, AFP/Getty Images)

Talk about the right stuff.

NASA on Wednesday named a dozen new astronauts seven men and five women selected from a record pool of more than 18,000applicants, more than double the previous high of 8,000.

You are the 12 who made it through, you have joined the elites, you are the best of us, Vice President Mike Pence said during a ceremony at Johnson Space Center in Houston."You carry on your shoulders the hopes and dreams of the American people."

NASA's diverse Class of 2017 includes six military officers, two of them doctors. It includesa marine biologist involved in Antarctic expeditions, a geologist who has worked with NASAs Mars Curiosity rover, and a SpaceX engineer who might ride a rocket and capsule he helped design.

We do things because they are hard, and then we crush it, said U.S. Air Force Lt. Col. Raja Chari, a 39-year-old test pilot from Iowa, when asked about the opportunity to fly a spaceship.

The group ranges in age from 29 to 42 andhails from 10 states. Each member holds an advanced degree.

Families and VIP guests cheered as the astronaut candidates, as they will be called until completing a two-year training program, walked onto a stage wearing blue NASA flight suits.

Chari was joined by Kayla Barron, 29; Zena Cardman, 29;Matthew Dominick, 35; Bob Hines, 42; Warren "Woody" Hoburg, 31;Dr. Jonny Kim, 33; Robb Kulin, 33; Jasmin Moghbeli, 33; Loral OHara, 34; Dr. Francisco"Frank" Rubio, 41; and Jessica Watkins, 29.

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The future astronauts might perform science research aboard the International Space Station, flying to the orbiting laboratory in Boeing Starliner or SpaceX Dragon capsules launching from Cape Canaveral, or in Russian Soyuz spacecraft.

They could be assigned to the first exploration missions beyond low Earth orbit since the last Apollo moon landing in 1972.

The 2017 astronaut class is NASAs 22nd, nearly 60 years after the 1959 introduction of the Mercury Seven amid a space race with the Soviet Union.

To apply, applicants had to be a U.S. citizen, have a degree in a science, technology, engineering or mathfield and at least three years of related experience, or at least 1,000 hours piloting jet aircraft.

Starting last year, selection teams winnowed the field of18,353applicants to 120 and then 50 finalists.

The astronauts-in-training will report to Houston in August to begin studying space station systems, learning Russian and flying T-38 jets.

Contact Dean at 321-242-3668 orjdean@floridatoday.com. And follow on Twitter at@flatoday_jdeanand on Facebook atfacebook.com/jamesdeanspace.

SpaceX successfully launched its Falcon 9 rocket on a mission to the International Space Station and landed the first stage at Cape Canaveral Air Force Station shortly after on Saturday, June 3, 2017.

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SpaceX's Falcon 9 launch included a 13,500-pound satellite that's close to the size of a double-decker bus. USA TODAY

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SpaceX launched a classified National Reconnaissance Office payload from Kennedy Space Center Monday morning and successfully landed the first stage of its Falcon 9 rocket.

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An Atlas V rocket blasts off from Cape Canaveral Air Force Station on Tuesday, April 18, 2017 with a Cygnus spacecraft for the International Space Station.

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In a historic first for the company and the industry, SpaceX launched and landed a "flight proven," or refurbished, Falcon 9 rocket from Kennedy Space Center.

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A Delta IV rocket carrying the military's WGS-9 satellite blasted off from Cape Canaveral Air Force Station on Saturday, March 18, 2017.

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SpaceX's Falcon 9 rocket blasts off from Kennedy Space Center with the EchoStar 23 communications satellite on Thursday, March 16, 2017.

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A SpaceX Falcon 9 rocket successfully blasted off from Kennedy Space Center's historic pad 39A on Sunday, Feb. 19, 2017. The first stage returned for a successful landing in Cape Canaveral Air Force Station.

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An Atlas V rocket blasts off from Cape Canaveral Air Force Station with the SBIRS missile detection satellite on Friday, Jan. 20, 2017.

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SpaceX launches Falcon 9 from KSC, lands at Cape

SpaceX launches satellite size of a double-decker bus

SpaceX launches Falcon 9 from KSC, nails landing

Atlas V rocket blasts off on mission with Cygnus spacecraft

SpaceX launches, lands 'flight proven' Falcon 9

Delta IV rocket launches from Cape Canaveral

SpaceX Falcon 9 rocket launches from Kennedy Space Center

Falcon 9 blasts off from KSC, lands at Cape

Atlas V rocket blasts off with missile detection satellite

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NASA had a record pool of 18000 applicants to be an astronaut. These 12 made it. - USA TODAY

NASA’s Mars Rover concept looks like the ultimate extraterrestrial golf cart – GolfDigest.com

Posted on June 8, 2017 by Danzig

On February 6th, 1971, Alan Shepherd, pulled out a 6-iron, lined up his approach, and let flyan occurrence that wouldn't be worth noting if weren't for the fact that it HAPPENED ON THE GOD DAMN MOON. 46 years later, Shepherd's (literal) moon shot remains the only instance of a human playing golf anywhere other than earth, but as NASA's Martian explorations intensify, it's time to set our sights on the dry, windswept links of Red Planet CC.

To that end (and, you know, science's too), on Thursday morning NASA unveiled their 2020 Mars Rover, a 6-wheeled research behemoth intergalactic golf machine, replete with on-course GPS, shot-tracker technology (on the premium model), and a mobile laboratory that can hold a couple sets of clubs when you're not using it to collect rare protein samples that might hold the key to extraterrestrial life.

Oh, and as if that's not enough, the Mars Rover conceptNASA says this bad boy will look A LOT different by the time it hits the first tee/Marsalso comes with an emergency life support system, which is sure to come in handy when that three putt on 18 looses the inevitable, golf-induced aneurism you've been holding back for years.

NASA's Mars Rover concept looks like the ultimate extraterrestrial golf cart - GolfDigest.com

Two 2017 NASA Astronaut Candidates have ties to Hampton Roads – wtkr.com

Posted on June 8, 2017 by Danzig

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NASA hasselected 12 men and women as their newest class of astronaut recruits. Among them are a man and woman with ties to Hampton Roads!

The 12 candidates were chosen from a pool of 18,300+ applicants, which is more than double the previous record of 8,000 set in 1978.

The 2017 NASA Astronaut Class: (from left) Zena Cardman, Jasmin Moghbeli, Jonny Kim, Frank Rubio, Matthew Dominick, Warren Hoburg, Robb Kulin, Kayla Barron, Bob Hines, Raja Chari, Loral O' Hara and Jessica Watkins. Photo Credit: NASA/Robert Markowitz

Zena Cardman

One of the chosen candidates is Zena Cardman, 29, a native of Williamsburg and graduate of Bruton High School who is currently National Science Foundation Graduate Research Fellow working on her doctorate at The Pennsylvania State University. Cardman has completed both a Bachelor of Science degree in Biology and a Master of Science degree in Marine Sciences at The University of North Carolina, Chapel Hill. NASA says her research has focused on microorganisms in subsurface environments, ranging from caves to deep sea sediments. Her field experience includes multiple Antarctic expeditions, work aboard research vessels as both scientist and crew, and NASA analog missions in British Columbia, Idaho and Hawaii.

Matthew Dominick

Matthew Dominick, 35, is another one of the chosen candidates with ties to Hampton Roads. Dominick is a Lieutenant Commander in the U.S. Navy and although he is a Colorado native, he was stationed at Naval Air Station Oceana for some time as part of Strike Fighter Squadron 106 and Strike Fighter Squadron 143. He has graduated from the U.S. Naval Test Pilot School and has logged more than 1,600 hours of flight time in 28 aircraft, 400 carrier-arrested landings, and flown 61 combat missions. He has a Bachelor of Science in Electrical Engineering from the University of San Diego and a Master of Science degree in Systems Engineering from the Naval Postgraduate School.Dominick is currently a part of Strike Fighter Squadron 115, forward stationed in Atsugi, Japan. He was at sea on the USS Ronald Reagan when he learned of his selection as an Astronaut Candidate.

Cardman, Dominick and the 10 other Astronaut Candidates will report for duty in August to begin their training.

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NASA’s Asteroid-Hunting NEOWISE Discovers Trove of 114 Objects (Video) – Space.com

Posted on June 8, 2017 by Danzig

NASA's prolific Near-Earth Object Wide-field Survey Explorer (NEOWISE) mission has returned a treasure trove of observations about asteroids, comets and other celestial objects within Earth's cosmic neighborhood.

Since 2013, when NASA reactivatedits WISE observatory a the NEOWISE mission, the infrared space telescope has discovered 114 previously unknown objects, 97 of them in the last year alone, according to NASA's Jet Propulsion Laboratory (JPL). That lab oversees the mission from Pasadena, California. The mission has characterized about 693 objects in all, many of them previously known, so far. [In Images: Potentially Dangerous Asteroids]

"NEOWISE is not only discovering previously uncharted asteroids and comets, but it is [also] providing excellent data on many of those already in our catalog," NEOWISE principal investigator Amy Mainzer of JPLsaid in a statement. "It is also proving to be an invaluable tool in the refining and perfecting of techniques for near-Earth object discovery and characterization by a space-based infrared observatory."

This animation shows the progress of NASA's Near-Earth Object Wide-field Survey Explorer, or NEOWISE, mission during its first three years. The mission began with the WISE space telescope's reactivation in December 2013.

An animation of NEOWISE data collected since 2013 shows the mission's progress. In the graphic, comets appear as yellow squares and asteroids are marked as gray dots. Green dots represent asteroids and comets that approach within 1.3 astronomical units of the sun. One astronomical unit is the distance between the Earth and sun, about 93 million miles (150 million kilometers).

The NEOWISE mission began its life as NASA'sWide-field Infrared Survey Explorer(WISE), an infrared space telescope that launched in 2009. That mission ended in 2011, and the observatory was placed in hibernation.

But in September 2013, NASA reactivated WISE to begin the NEOWISE mission, a project specifically aimed at helping scientists seek out and identify potentially hazardous asteroids and comets.

Email Tariq Malik at tmalik@space.com or follow him@tariqjmalikandGoogle+. Follow us@Spacedotcom,FacebookandGoogle+. Original article onSpace.com.

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NASA's Asteroid-Hunting NEOWISE Discovers Trove of 114 Objects (Video) - Space.com

Americans ‘under siege’ from climate disinformation former Nasa chief scientist – The Guardian

Posted on June 8, 2017 by Danzig

A constant barrage of half-truths has left many Americans confused about the potential consequences of continued carbon emissions, despite the science being unequivocal, says Ellen Stofan. Photograph: Saul Loeb/Getty Images

Americans are under siege from disinformation designed to confuse the public about the threat of climate change, Nasas former chief scientist has said.

Speaking to the Guardian, Ellen Stofan, who left the US space agency in December, said that a constant barrage of half-truths had left many Americans oblivious to the potentially dire consequences of continued carbon emissions, despite the science being unequivocal.

We are under siege by fake information thats being put forward by people who have a profit motive, she said, citing oil and coal companies as culprits. Fake news is so harmful because once people take on a concept its very hard to dislodge it.

During the past six months, the US science community has woken up to this threat, according to Stofan, and responded by ratcheting up efforts to communicate with the public at the grassroots level as well as in the mainstream press.

The harder part is this active disinformation campaign, she said before her appearance at Cheltenham Science Festival this week. Im always wondering if these people honestly believe the nonsense they put forward. When they say It could be volcanoes or the climate always changes to obfuscate and to confuse people, it frankly makes me angry.

Stofan added that while fake news is frequently characterised as a problem in the right-leaning media, she saw evidence of an erosion of peoples ability to scrutinise information across the political spectrum. All of us have a responsibility, she said. Theres this attitude of I read it on the internet therefore it must be true.

Stofan resigned from her post at the top of Nasa in December, before the US election results. It wasnt anything to do with it, but Im glad Im not there now, she said.

However, she welcomed the continued commitment to Nasas Mars program in the most recent budget and was relieved that cuts to the agencys Earth observation program, which contributes to climate and environment monitoring, were relatively small, at $167m (the total Earth science budget is now $1.754bn).

Throughout her career, Stofan has highlighted the role of planetary science in understanding the Earths environment and said it provided some of the most inarguable proof that atmospheric carbon dioxide leads to a warmer climate. She draws parallels between carbon emissions on Earth and the runaway greenhouse effect on Venus, a planet which once had oceans but is now a toxic inferno with surface temperatures approaching 500C.

The Earth is not destined for such an extreme scenario even if all the CO2 were burned its oceans would not boil off completely but Venus demonstrates the dramatic changes that can unfold when the fine balance of planets atmosphere is tipped.

We wont go all the way to Venus, but the consequences of putting more and more CO2 into the atmosphere are really dire, she said. There are models that suggest if we burn off all our fossil fuels, the Earth would become uninhabitable for humans.

The quest to find habitable zones beyond the Earth has been a major motivation throughout Stofans scientific career and she said that the answer to the question of the existence of extraterrestrial life-forms suddenly seems within reach.

Missions to capture water coming from the plumes of Europa and Enceladus, could yield the first indications. The search is requiring scientists to be imaginative and open-minded about what alien life might look like it might involve complex molecules, but be DNA-free, for instance.

The uncertainty over what hypothetical alien life would even look like means that any initial discovery could be ambiguous and a source of scientific dispute, Stofan predicts. It would be great if when we found life it was easy and we image a droplet of liquid and something goes swimming across it, no ones going to disagree with that, she said.

A more realistic scenario is that it would take decades for confirmation, and this reasoning is why Stofan is a strong advocate of a manned Mars mission, arguing that a robotic rover would not be capable of reliably confirming the existence of life, past or present, that might be lurking beneath the surface.

Human explorers could operate drills designed to extract soil samples from far deeper than the few inches achieved by Nasas Curiosity rover, or the two metres limit anticipated for Esas upcoming ExoMars mission, and could perform more sophisticated scientific analysis. She predicts humans could orbit the red planet within 20 years and reach the surface in 30.

I still feel that to settle the question and to have agreement its going to have a lot of samples and a lot of analysis and to me that means humans, she said.

However, she dismissed the idea, popularised by Stephen Hawking and Elon Musk, that mankind should be preparing to colonise other planets to avoid self-annihilation. I dont see a mass transfer of humanity to Mars, ever, she said, adding that she had been concerned recently when a teacher told her that her pupils thought the climate doesnt matter as well all go and live on Mars.

Job one is to keep this planet habitable. Id hate us to lose focus on that, she said.

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Americans 'under siege' from climate disinformation former Nasa chief scientist - The Guardian

Nanotechnology reveals hidden depths of bacterial ‘machines’ – Phys.Org

Posted on June 8, 2017 by Danzig

June 8, 2017 Illustration of a carboxysome. Credit: Dr Luning Liu, University of Liverpool

New research from the University of Liverpool, published in the journal Nanoscale, has probed the structure and material properties of protein machines in bacteria, which have the capacity to convert carbon dioxide into sugar through photosynthesis.

Cyanobacteria are a phylum of bacteria that produce oxygen and energy during photosynthesis, similar to green plants. They are among the most abundant organisms in oceans and fresh water. Unique internal 'machines' in cyanobacteria, called carboxysomes, allow the organisms to convert carbon dioxide to sugar and provide impacts on global biomass production and our environment.

Carboxysomes are nanoscale polyhedral structures that are made of several types of proteins and enzymes. So far, little is known about how these 'machines' are constructed and maintain their organisation to perform carbon fixation activity.

Researchers from the University's Institute of Integrative Biology, led by Royal Society University Research Fellow Dr Luning Liu, examined in depth the native structure and mechanical stiffness of carboxysomes using advanced microscopes and biochemical approaches.

For the first time, the researchers were able to biochemically purify active carboxysomes from cyanobacteria and characterize their carbon fixation activity and protein composition. They then used electron microscopy and atomic force microscopy to visualise the morphology and internal protein organization of these bacterial machines.

Furthermore, the intrinsic mechanical properties of the three-dimensional structures were determined for the first time. Though structurally resembling polyhedral viruses, carboxysomes were revealed to be much softer and structurally flexible, which is correlated to their formation dynamics and regulation in bacteria.

Dr Liu, said: "It's exciting that we can make the first 'contact' with these nano-structures and understand how they are self-organised and shaped using state-of-the-art techniques available at the University. Our findings provide new clues about the relationship between the structure and functionality of native carboxysomes."

The self-assembly and modularity features of carboxysomes make them interesting systems for nanoscientists, synthetic biologists and bioengineers, who hope to find ways to design new nanomaterials and nano-bioreactors.

"We're now just starting to understand how these bacterial machines are built and work in nature. Our long-term vision is to harness the knowledge to make further steps towards better design and engineering of bio-inspired machines," added Dr Liu, "The knowledge and techniques can be extended to other biological machines."

Explore further: Illuminating the inner 'machines' that give bacteria an energy boost

More information: Matthew Faulkner et al, Direct characterization of the native structure and mechanics of cyanobacterial carboxysomes, Nanoscale (2017). DOI: 10.1039/C7NR02524F

Journal reference: Nanoscale

Provided by: University of Liverpool

Scientists at the University of Liverpool have tracked how microscopic organisms called cyanobacteria make use of internal protein 'machines' to boost their ability to convert carbon dioxide into sugar during photosynthesis.

Cyanobacteria, found in just about every ecosystem on Earth, are one of the few bacteria that can create their own energy through photosynthesis and "fix" carbon from carbon dioxide molecules and convert it into fuel ...

(Phys.org) A genetically engineered tobacco plant, developed with two genes from blue-green algae (cyanobacteria), holds promise for improving the yields of many food crops.

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Researchers at Michigan State University have built a molecular Swiss Army knife that streamlines the molecular machinery of cyanobacteria, also known as blue-green algae, making biofuels and other green chemical production ...

An international team of scientists led by Uppsala University has developed a high-throughput method of imaging biological particles using an X-ray laser. The images show projections of the carboxysome particle, a delicate ...

When oil mixes with or enters into water, conventional methods of cleaning the water and removing the oil can be challenging, expensive and environmentally risky. But researchers in the Cockrell School of Engineering at The ...

The endothelial cells that line blood vessels are packed tightly to keep blood inside and flowing, but scientists at Rice University and their colleagues have discovered it may be possible to selectively open gaps in those ...

Recent research from the University of Nebraska-Lincoln may help future engineers of digital components get two (or more) for the space of one.

Scientists at Johns Hopkins have created a nanoparticle that carries two different antibodies capable of simultaneously switching off cancer cells' defensive properties while switching on a robust anticancer immune response ...

Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have developed a new way to track dynamic molecular features in soft materials, including the high-frequency molecular vibrations that transmit ...

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Nanotechnology reveals hidden depths of bacterial 'machines' - Phys.Org

NSF Announces 2017 Winners for Generation Nano: Small Science, Superheroes – Controlled Environments Magazine

Posted on June 8, 2017 by Danzig

On June 6, the National Science Foundation (NSF), in partnership with the National Nanotechnology Initiative (NNI), named the first- and second-place winners, as well as the People's Choice winner, for the second annual Generation Nano competition.

Generation Nano challenges high school students to imagine novel superheroes who use the power of nanotechnology -- technology on the scale of a nanometer, or 1 billionth of a meter -- to solve crimes or tackle a societal challenge. Students then tell their hero's story in a comic and video. Students learn about the science behind nanotechnology before applying nanotechnology-enabled tools and concepts to futuristic characters, said Mihail C. Roco, NSF senior advisor for science and engineering and a key architect of the National Nanotechnology Initiative (NNI).

"This competition is like a real-life exercise in modern society, where creativity and rigor combine to engineer novel products, smart infrastructure, life-saving medical treatments and more," Roco said. "Students use their imaginations to join emerging uses of nanotechnology with other fields, bringing new viewpoints and collective interest to scientific progress. The younger generation needs such skills, as they will live and work in a more advanced society than their teachers, and we wish success to all of them as they help create the future of nanotechnology."

The winners

"I was so impressed by the imaginative ways that students used nanotechnology to ease human suffering, cure disease, fight criminals and clean up the environment in this year's Generation Nano contest," said Lisa Friedersdorf, director of the National Nanotechnology Coordination Office. "The winning comics showcase the importance of creatively applying science to solve problems. I am sure these comics and videos will excite other students and inspire them to think about how they can use nanotechnology to improve the world."

Students' superhero creations had to address one of four missions using their nanotechnology powers:

Generation Nano participants were required to submit a short, written entry about their superheroes, a two- to three-page comic and a 90-second video. A panel of judges with expertise in either nanotechnology or comics evaluated each entry and selected semifinalists and finalists. The public selected the People's Choice winner from the list of finalists.

The judges

The winners will be at the NSF booth at Awesome Con in Washington, D.C. June 16-18, and will also visit Capitol Hill. In addition, each winner is invited to tour the nearest NNI center.

Visit the Generation Nano website for competition details, such as eligibility criteria, entry guidelines, timeline, prizes, and videos and comics from the winners and finalists.

College, Grad School, and Post Doc Opportunities | Nano

Posted on June 8, 2017 by Danzig

As progress for nanotechnology research and development picks up speed, more and more universities in the U. S. are beginning to offer degree programs in nanotechnology. These programs now range from minor and majors in nanotechnology to Masters' programs to PhD's in any number of nanotechnology-related fields.

For those students seeking a higher education at a college or university that doesnt offer a degree in nanoscience, a student could choose to go into chemistry, physics, engineering, biology, IT, or another technology fields. With the help of a college advisor or a trusted professor or mentor, students can navigate college-level science courses to learn a great deal about nanotechnology. And keep in mind that the further you get in your education, the greater the options and choices that become available to you.

NASA Space TechnologyResearchFellowships (NSTRF)The goal of NSTRF is to sponsor U.S. citizen and permanent resident graduate students who show significant potential to contribute to NASAs goal of creating innovative new space technologies for our Nations science, exploration and economic future. NASA Space Technology Fellows will perform innovative, space-technology research at their respective campuses and at NASA Centers and/or at nonprofit U.S. Research and Development (R&D) laboratories. Awards are made in the form of training grants to accredited U.S. universities on behalf of individuals pursuing masters or doctoral degrees, with the faculty advisor serving as the principal investigator.

NASA Postdoctoral Program NASA Postdoctoral Program (NPP) supports NASAs goal to expand scientific understanding of the Earth and the universe in which we live.Selected by a competitive peer-review process, NPP Fellows complete one- to three-year Fellowship appointments that advance NASAs missions in earth science, heliophysics, planetary science, astrophysics, space bioscience, aeronautics and engineering, human exploration and space operations, and astrobiology.

Research Experience for Undergraduates (REU)NSF funds a large number of research opportunities for undergraduate students through its REU Sites program. Each student is associated with a specific research project, where he/she works closely with the faculty and other researchers. Undergraduate students supported with NSF funds must be citizens or permanent residents of the United States or its possessions.

NIST Summer Undergraduate Research Fellowship (SURF) program All six of the NIST laboratories in Gaithersburg, MD, participate in SURF programs. For example, the Materials Measurement Laboratory (MML) and the NIST Center for Neutron Research (NCNR) SURF program is designed to provide hands-on research experience in Ceramics, Metallurgy, Polymers, Condensed Matter Science, and Materials Reliability; available research opportunities in theMML/NCNR SURF programinclude structural and magnetic properties of nanomaterials. NIST also offersSURF research opportunities in Boulder, CO.

Science, Mathematics, & Research for Transformation (SMART) Scholarship for Service Program The SMART Scholarship for Service Program has been established by the DOD to support undergraduate and graduate students pursuing degrees in science, technology, engineering, and mathematics (STEM) disciplines. The program is an opportunity for students to receive a full scholarship and be gainfully employed upon degree completion. The program aims to increase the number of civilian scientists and engineers working at DOD laboratories.

NSF's NanoJapan International Research Experience for Undergraduates Recognized as a model for international education programs for science and engineering students, NanoJapan provides U.S. undergraduates with structured research opportunities in Japanese university laboratories with Japanese mentors.The strong educational portfolio of this project focuses on cultivating interest in nanotechnology among young U.S. undergraduate students, especially those from underrepresented groups, and encouraging such students to pursue graduate study and academic research in the physical sciences.

Intelligence Community Postdoctoral Research Fellowship Program Established in 2000 to fund basic research in areas of interest to the Intelligence Community, today, the program annually funds first- and second-year postdoctoral fellows researching topics as varied as molecular biology and robotics.

National Institute of Biomedical Imaging and Bioengineering Training NIH/NIBIB training opportunities are geared for undergraduate, graduate, and post-doctoral candidates. See also theNIBIB Funding pageand theNIH Training and Educationpage.

NIH's Cancer Nanotechnology Training Centers(CNTCs)CNTCs are designed to establish innovative research education programs supporting the development of a multi-disciplinary nanotechnology workforce capable of pursuing cancer research. CNTCs target graduate student and post-doctoral researchers with backgrounds in medicine, biology, and other health sciences as well as in the physical sciences, chemistry, and engineering. The program of multi-disciplinary research education in cancer nanotechnology is primarily focused on mentored laboratory-based training through participation in dedicated training research projects. (See an updated list on our NNI R&D Centers page.)

Degree Programs

Below is a list of degree programs, including Bachelors degrees with majors, minors and concentrations; Masters degrees; and PhD programs.

Boston University - Concentration in nanotechnology

Clarion University Minor in nanotechnology

Drexel University BSc Materials Engineering with Specialization Nanotechnology

Excelsior College - B.S. in Electrical Engineering Tech with Nanotechnology concentration

Georgia Tech - B.S. in Electrical Engineering with Nanosystems Specialization

Hampton University - Minor in Nanoscience

Johns Hopkins University - B.S. in Materials Science and Engineering, concentration in nanotechnology

Lock Haven University - B.S. in Applied Physics (Nanotechnology Track)

Louisiana Tech University B.S. in Nanosystems Engineering

Michigan Technological University B.S. in Physics withminor in nanotechnology

New Jersey Institute of Technology - Minor in nanotechnology

North Carolina State University, NANO@NCState program - B.S. with nanotechnology concentration

Northwestern University B.S. in Physics with Nanoscale Physics Concentration

Oregon State University - B.S. in Chemical Engineering with nanotechnology processes option

Pennsylvania State University - Minor in nanotechnology; Nanofabrication Manufacturing Technology capstone semester

Rice UniversityB.S. in Electrical and Computer Engineering withConcentration in Photonics and Nanodevices, orB.S. in Materials Science andNanoengineering

Rutgers University B.S. program in Materials Science and Engineeringwith a focus on nanomaterials

Stanford University - B.S. Materials Science and Engineering with nanotechnology concentration

SUNY Polytechnic Institute Colleges of Nanoscale Science and Engineering B.S. in Nanoscale Science or Nanoscale Engineering

University of California, Riverside B.S. in Materials Science with a concentration in nanomaterials and sensors; B.S. in Electrical and Computer Engineering with a concentration in nanotechnology;B.S. in Chemical and Environmental Engineering with a nanotechnology concentration

University of California, San Diego B.S. Nanoengineering

University of Central Florida B.S. in Nanoscience and Nanotechnology track in Liberal Studies

University of Cincinnatti - Minor in Nanoengineering; Minor in Nanoscience and Nanotechnology

University of Connecticut - Minor in Nanotechnology

University of Illinois at Urbana-Champaign - B.S. with Nanotechnology Concentration

University of Maryland, Materials Science and Engineering Interdisciplinary minor in nanotechnology

University of Notre Dame -B.S. w/ Concentration in Seminconductors and Nanotechnology

University of Southern California -Minor in Nanotechnology

University of Utah -B.S. w/ Emphasis in Micro/Nanoscale Engineering

University of Washington B.S. w/ Nanoscience and Molecular Engineering Option

Virginia Tech University -B.S. in Nanoscience

Washington State University, Nanotechnology Think Tank -B.S. w/ Specialization in Nanotechnology

Arizona State University Professional Science Master (PSM) in Nanoscience and M.A. in Applied Ethics (Ethics and Emerging Technologies)

Cornell University - M.S. Applied Physics with Nanotechnology Specialization

Johns Hopkins University M.S. with Concentration in Nanotechnology; Nano-Bio Graduate Training Program

Joint School of Nanoscience and Nanoengineering (collaborative project of North Carolina A&T State Univ. and Univ. of North Carolina Greensboro) M.S. in Nanoscience and M.S. in Nanoengineering

Louisiana Tech University M.S. in Molecular Sciences and Nanotechnology

North Carolina State University - M.S. in Nanoengineering

North Dakota State University M.S. in Materials and Nanotechnology

Northwestern University -M.S. withSpecialization in Nanotechnology

Princeton University see Rutgers listing for joint program

Radiological Technologies University VT (Indiana) M.S. in Nanomedicine

Rice University, Center for Nanoscale Science and Technology Professional Science Master (PSM) in Nanoscale Physics

Rutgers, The State University of New Jersey and Princeton University- Intergrative Graduate Education Research Traineeship (IGERT) in Nanotechnology for Clean Energy

Singapore-MIT Alliance M.Eng. Advanced Materials for Micro- and Nano-Systems

Stevens Institute of Technology M.Eng. with Nanotechnology Concentration and M.S. with Nanotechnology Concentration

SUNY Polytechnic Institute Colleges of Nanoscale Science and Engineering M.S. in Nanoscale Science and Nanoscale Engineering

University of California, Riverside Online M.S. Nanotechnology Engineering

University of California, San Diego M.S. Nanoengineering

University of Central Florida - M.S. and P.S.M in Nanotechnology

University of Illinois Urbana-Champaign -Cancer Nanotechnology Concentration

University of New Mexico M.S. in Nanoscience and Microsystems

University of Pennsylvania M.S. in Nanotechnology

University of South Florida - M.S. in Pharmaceutical Nanotechnology

University of Texas at Austin M.S. withNanomaterials Thrust Area

City University of New York - Nanotechnology and Materials Science

Joint School of Nanoscience and Nanoengineering - Nanoscience or Nanoengineering

Louisana Tech University - Micro/Nanoelectronics and Micro/Nanotechnology

North Dakota State University - Materials and Nanotechnology

Northeastern University, NSFs Integrative Graduate Education and Research Traineeship (IGERT) - Ph.D. in Nanomedicine

Northwestern University - Specialization in Nanotechnology

Rice University - Materials Science and NanoEngineering

South Dakota School of Mines and Technology Nanoscience and Engineering program

Stevens Institute of Technology - Nanotechnology Graduate Program

SUNY Polytechnic Institute Colleges of Nanoscale Science and Engineering-Ph.D. in Nanoscale Science or Engineering or Medicine; M.D. in Nanoscale Medicine

University of California, Berkeley - Nanoscale Science and Engineering

University of California, Los Angelos -Ph.D. Chemistry w/ Materials and Nanoscience Specialization

University of California, San Diego - Nanoengineering

University of New Mexico - Nanoscience and Microsystems

University of North Carolina at Charlotte -Ph.D. Program in Nanoscale Science

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College, Grad School, and Post Doc Opportunities | Nano

UQ, partners taking computing out of this world – Phys.org – Phys.Org

Posted on June 8, 2017 by Danzig

June 8, 2017

University of Queensland researchers have partnered with global technology leader Lockheed Martin to develop next generation computers for aerospace applications.

ARC Future Fellow and project lead Professor Warwick Bowen said the partnership would develop a new approach to computer technology, with the potential for future commercial impacts in the aerospace industry.

"In contrast to today's computers, which rely on electric currents, this new approach will use mechanical vibrations inside the computer chip to perform computations," Professor Bowen said.

"This makes it much more robust to radiation exposure in near-earth orbit and deep space applications.

"An expected further project outcome is the development of nanotechnologies that could have wide uses in sensing, health and communications.

"The project could also improve heat management and energy efficiency in future computers."

Speaking on the partnership with UQ, Lockheed Martin Australia Chief Executive Vince Di Pietro said Lockheed Martin had a long history of collaborative research and innovation across the globe, including investment in the world's best research in Australia.

"By leveraging an existing contract established through our Global Supply Chain Enabled Innovation program into this ARC Linkage grant with UQ, we see a true partnership between industry, academia and government growing Australia's future defence industry capability," Mr Di Pietro said.

Chief investigator Dr Rachpon Kalra, awarded a UQ Development Fellowship to work with Lockheed Martin Australia, said the project would strengthen UQ's ties to one of the world's largest aerospace companies.

Fellow chief investigator Dr Christopher Baker said the project built upon UQ's expertise in nanotechnology and nanoengineering.

UQ made a recent multi-million dollar investment in nation-leading nanofabrication tools capable of building devices with features only a few tens of atoms in size.

The project is part of the University of Queensland Precision Sensing Initiative, a joint initiative of the Schools of Mathematics and Physics and of Information Technology and Electrical Engineering.

It will benefit from substantial Federal Government investment into the Australian Centre of Excellence for Engineered Quantum Systems, which aims to develop next generation quantum technologies for future Australian industries.

Federal Minister for Education and Training Simon Birmingham announced the funding last month, making it one of four UQ proposals that attracted $1.28 million in Australian Government funding through the Australian Research Council (ARC) Linkage Projects scheme.

The computers for aerospace project received $334,710 Federal Government funding, with cash and in-kind funding by the University and industry partner.

Dr Luke Uribarri from Lockheed Martin will be the fourth investigator on the project.

Explore further: Lockheed Martin to deliver world record-setting 60kw laser to U.S. Army

Lockheed Martin has completed the design, development and demonstration of a 60 kW-class beam combined fiber laser for the U.S. Army.

Digital Array Row Transceiver (DART) provides greater performance thanks to improved reliability and increased efficiency

Lockheed Martin and Dominion Resources, Inc. have co-developed a new smart grid technology called VirtuGrid, which will enable remote detection of power outages for faster mapping and response. This collaboration between ...

A major Chinese investment in graphene research plans to deliver lighter, better performing aircraft and high-speed trains.

Thousands of electrical components make up today's most sophisticated systems and without innovative cooling techniques, those systems get hot. Lockheed Martin is working with the Defense Advanced Research Projects Agency ...

(Phys.org) Hong Kong based Reignwood Group and U.S. aerospace company Lockheed Martin have announced plans to build an Ocean Thermal Energy Conversion (OTEC) electricity generating plant off the coast of China to power ...

An AI machine has taken the maths section of China's annual university entrance exam, finishing it faster than students but with a below average grade.

Globally, from China and Germany to the United States, electric vehicle (EV) subsidies have been championed as an effective strategy to boost production of renewable technology and reduce greenhouse gas emissions (GHG).

As global automakers compete to bring the first flying car to market, Czech pilot Pavel Brezina is trying a different tack: instead of creating a car that flies, he has made a "GyroDrive"a mini helicopter you can drive.

Apple's new HomePod speaker may be music to the ears of its loyal fans, but how much it can crank up volume in the smart speaker market remains to be heard.

Autonomous vehicles with no human backup will be put to the test on publicly traveled roads as early as next year in what may be the first attempt at unassisted autonomous piloting.

Using Earth-abundant materials, EPFL scientists have built the first low-cost system for splitting CO2 into CO, a reaction necessary for turning renewable energy into fuel.

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UQ, partners taking computing out of this world - Phys.org - Phys.Org

Scholar Spotlight: Using Nano Technology, Amay Bandodkar Creates Self-Healing Wearable Devices – MilTech

Posted on June 8, 2017 by Danzig

Wearable technology has increasingly found its way into consumers lives, with the fitness tracker Fit Bit and smart watches like the Apple Watch leading the market.

In the future, we can expect to see more such wearable devicesincluding thin, small, flexible, sensors that adhere to the skin. Nano engineers have been creating prototypes of these sticker-like sensors that could have dozens of health care, consumer, and military applications.

Existing technologies present barriers to the practicality of the prototypes, however: They can tear easily, and their thin profile makes the use of batteries impractical. Nano engineer and Siebel Scholar Amay Bandodkar (University of California San Diego, BioE 16), has devoted his research to overcoming these limitations.

Siebel Scholar Amay Bandodkar is using nano technology to develop flexible and wearable health monitoring devices that use magnets to repair themselves.

As a doctoral student in the research lab of Dr. Joseph Wang at the Department of NanoEngineering at the University of California San Diego, Bandodkar worked on developing wearable devices that can sense chemicals and devices that can harvest energy from human sweat.

He also helped pioneer a breakthrough technology that enables wearable devices to heal themselves using magnetic particles. His team published an article describing the discovery in the November 2, 2016 issue of Science Advances.

Now a postdoctoral fellow at Northwestern University, Bandodkar is continuing his research on wearable chemical sensors. He is also researching implantable devices for monitoring brain activity. He is especially interested in developing devices for biomedical applications, such as monitoring ICU patients and people who have just undergone surgery.

Bandodkar spoke with the Siebel Scholars program about wearable devices, his research at Dr. Wangs lab, and the new paths hes forging at Northwestern.

Q: What will wearable electronic devices look like in the future?

In the very near future, wearable devices will conform to the skin. Think of a very thin, flexible, patch that you apply directly to the body, and which moves and breathes with the skin. The user wont even feel its presence.

These devices will monitor an array of vital parameters, such as glucose levels, electrolytes, heart rates, temperature, and stress levels. Multiple sensors on the body will interact, sending each other information, and to sensors on other people.

Right now, for instance, a pregnant woman needs to see her gynecologist to know the status of her baby and her own health. A wearable or implantable system could continuously monitor the health of the mother and baby and wirelessly transmit that information to the hospital or clinic without the need for a doctors visit.

In a military application, sensors placed on soldiers can keep a commanding officer updated on soldiers fitness levels. This information can help inform decisions about who needs a break in the action. For people with diabetes, sensors could track glucose levels and make needle prick tests obsolete.

Q: Your research on self-healing devices has undergone a few iterations. What steps did you take before you got to this latest breakthrough?

Wearable devices can be expensive to make, but printing them can significantly drive down the cost. So this has become an attractive approach. Printed, wearable devices move with the users bodythey bend, stretch, and twist. But they usually break when they experience mechanical stress. We wanted to incorporate self-healing systems to extend the lifespan of these devices.

The first approach we took was to disperse microcapsules filled with organic solvents within the device. Where damage happened, the capsules broke and released the solvent, which helped form a bridge across the cracks. Within a few seconds you got conductivity and could use the device again. This had two problems: First, you cant use non-bio compatible solvents for wearable devices. Second, the solvent evaporates over time, limiting the lifespan of the device.

Other research groups have used self-healing polymers and other chemistries to initiate the self-healing process. Those approaches require that you manually trigger self-healing by exposing the device to heat or UV light and leave it for several hours or days. These systems are also very sensitive, so under certain weather conditions, they wont perform.

Q: How has your research overcome these limitations?

We came up with the idea of using magnets. Magnets attract each other. They are very inexpensive. And they will work under just about any weather condition.

We literally bought magnets at the supermarket, then ground them down into very fine particles and infused the ink with them. That worked. When the device split or broke, the magnetic particles attracted each other and it self-healed automatically, over and over. This is what we reported on in Science Advances.

You can the self-healing process in action in this video.

Q: All of these devices need power. Your research has helped devise novel ways to harness electricity. Tell us about that.

The groups I worked with at Dr. Wangs laboratory and at Northwestern are both exploring ways to circumvent the need for batteries. The problem with batteries is that they discharge and are bulky. During my Ph.D., I worked on developing wearable biofuel cells that can scavenge energy from human sweat. We recently demonstrated that such a system can power LED lights and even a Bluetooth device.

One of the biggest challenges is optimizing the ink compositionfinding the right balance of magnetic material, binder, and electric system components. If you put in too much magnetic material, the amount of the other components you can add decreases. There is a fixed amount of solid materials that can be suspended in a polymeric binder system. All of this material affects printability as well.

Q: Where is your research headed?

In my present lab, I am working on implantable devices that can monitor neurochemicals to measure brain activity as well as wearable non-invasive chemical sensors for fitness and health care applications.

I am currently exploring integrating near-field communications (NFC) technologiesthe kind used for applications such as Apple Payinto wearable patches to overcome the need for batteries. The patch will have a small antenna on it. When you tap your phone on it, the device will transmit information to your phone such as your glucose and sodium levels, temperature, and sweat rate.

Q: What inspired you to become a nano engineer?

I have always been interested in doing research. Every day offers a new challenge. I find it much more exciting than the prospect of a 9-5 job. Growing up in Mumbai, India, I knew I wanted to do my Ph.D. in the United States.

I began my graduate studies in 2011, not long after researchers had begun developing wearable devices. I wanted to be involved in the budding nano field. I was really excited to see how we could make chemical devices and sensors that could be integrated on wearable platforms.

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Scholar Spotlight: Using Nano Technology, Amay Bandodkar Creates Self-Healing Wearable Devices - MilTech

A new way to extend Moore’s law – The Economist

Posted on June 8, 2017 by Danzig

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Continued here:

A new way to extend Moore's law - The Economist

Molecular Genetics – Molecular Biology Conferences

Posted on June 8, 2017 by Danzig

Sessions/Tracks

Track 1:Molecular Biology

Molecular biologyis the study of molecular underpinnings of the processes ofreplication,transcription,translation, and cell function. Molecular biology concerns themolecularbasis ofbiologicalactivity between thebiomoleculesin various systems of acell,gene sequencingand this includes the interactions between theDNA,RNAand proteinsand theirbiosynthesis. Inmolecular biologythe researchers use specific techniques native to molecular biology, increasingly combine these techniques and ideas from thegeneticsandbiochemistry.

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2nd World Congress onHuman Genetics&Genetic Disorders, November 02-03, 2017 Toronto, Canada; 9th International Conference onGenomicsandPharmacogenomics, June 15-16, 2017 London, Uk; 6th International Conference and Exhibition onCellandGene Therapy, Mar 27-28, 2017 Madrid, Spain; Gordon Research Conference,Viruses&Cells, 14 - 19 May 2017, Lucca, Italy;Human Genome Meeting(HGM 2017), February 5-7 2017, Barcelona, Spain; Embl Conference:Mammalian GeneticsAndGenomics:From Molecular Mechanisms To Translational Applications, Heidelberg, Germany, October 24, 2017;GeneticandPhysiological Impacts of Transposable Elements, October 10, 2017, Heidelberg, Germany.

American Society for Cell Biology;The Society for Molecular Biology & Evolution;American Society for Biochemistry and Molecular Biology;The Nigerian Society of Biochemistry and Molecular Biology;Molecular Biology Association Search Form - CGAP.

Track 2:Gene Therapy and Genetic Engineering

Thegenetic engineeringis also called asgenetic modification. It is the direct manipulation of an organism'sofgenomeby usingbiotechnology. It is a set of technologies used to change the genetic makeup of the cell and including the transfer of genes across species boundaries to produce improved novelorganisms. Genesmay be removed, or "knocked out", using anuclease.Gene is targetinga different technique that useshomologousrecombinationto change anendogenous gene, and this can be used to delete a gene, removeexons, add a gene, or to introducegenetic mutations. There is an dna replacement therapy, Genetic engineering does not normally include traditional animal and plant breeding, gene sequencing, in vitro fertilization, induction of polyploidy,mutagenesisand cell fusion techniques that do not use recombinant nucleic acids or a genetically modified organism in the process,diseases treated with gene therapywas initially meant to introduce genes straight into human cells, focusing on diseases caused by single-gene defects, such as cystic fibrosis, hemophilia, muscular dystrophy and sickle cell anemia

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8thWorld Congress onMolecular Pathology, June 26-27, 2017 San Diego, USA; 11thInternational Conference onSurgical Pathology& Practice, March 27-28, 2017, MADRID, SPAIN; 13th EuropeanPathologyCongress, Aug 02-03, 2017, MILAN, ITALY; 28th Annual Meeting, Austrian Society ForHuman GeneticsAnd The Swiss Society OfMedical GeneticsCombined Meeting 2017 march 29, 2017 - March 31, 2017, bochum , Germany.

Association for Clinical Genetic Science;Genetics Society of America | GSA;Association of Genetic Technologists;Molecular Genetics - Human Genetics Society of Australasia;Genetic Engineering - Ecological Farming Association.

Track 3:Cell & Gene Therapy

Cell therapy is also calledcellular therapyorCyto therapy, in which cellular material is injected into patient this generally means intact, living cells. The first category iscell therapyin mainstream medicine. This is the subject of intense research and the basis of potential therapeutic benefit. Such research can be controversial when it involves human embryonic material. The second category is in alternative medicine, and perpetuates the practice of injecting animal materials in an attempt to cure disease.Gene therapyis the therapeutic delivery of nucleic acid polymers into a patient's cells as a drug to treat disease. Gene therapy is a way to fix agenetic problemat its source. The polymers are either translated into proteins, interfere with targetgene expression, or possibly correct genetic mutations. The most common form uses DNA that encodes a functional,therapeutic gene to replace a mutated gene. The polymer molecule is packaged within a "vector", which carries the molecule inside cells. Vectors used in gene therapy, the vector incorporates genes intochromosomes. The expressed nucleases then knock out and replace genes in the chromosome. The Center forCell and Gene Therapyconducts research into numerous diseases, including but not limited to PediatricCancer, HIV gliomaandCardiovascular disease.

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2nd World Congress onHuman Genetics&Genetic Disorders, November 02-03, 2017 Toronto, 27 Canada ; 7th International Conference onPlant Genomics, July 03-05, 2017, Bangkok, Thailand ; American Society ofGeneandCell Therapy(ASGCT) 20th Annual Meeting, 10 - 13 May 2017, Washington, DC;Genomic Medicine for Clinicians(course), January 25-27, 2017, Hinxton , Cambridge, UK; Embo Conference:ChromatinandEpigenetics, Heidelberg, Germany, May 3, 2017; 14th International Symposium on Variants in theGenomeSantiago de Compostela, Galicia, Spain, June 5 - 8, 2017;

Genetics and Molecular Medicine - American Medical Association;Genetics Society of America / Gsa;British Society for Genetic Medicine;British Society for Gene and Cell Therapy; Australasian Gene Therapy Society.

Track 4:Cell Cancer Immunotherapy

Immunologydeals with the biological and biochemical basis for the body's defense against germs such as bacteria, virus and mycosis (fungal infections) as well as foreign agents such asbiological toxinsand environmental pollutants, and failures and malfunctions of these defense mechanisms. Cancer immunotherapy is the use of the immune system to treat cancer. Immunotherapies can be categorized as active, passive or hybrid (active and passive). Antibodies are proteins produced by the immune system that bind to a target antigen on the cell surface. The immune system normally uses them to fight pathogens. A type of biological therapy that uses substances to stimulate or suppress the immune system to help the body fight cancer, infection, and other diseases. Some types of immunotherapy only target certain cells of the immune system. Others affect the immune system in a general way. Types of immunotherapy include cytokines, vaccines, bacillus Calmette-Guerin (BCG), and some monoclonal antibodies.

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9thAnnual Meeting onImmunologyandImmunologist, July 03-05, 2017 Kuala Lumpur, Malaysia; 8th MolecularImmunology&ImmunogeneticsCongress, March 20-21, 2017 Rome, Italy; 8th EuropeanImmunologyConference, June 29-July 01, 2017 Madrid, Spain; July 03-05, 2017; B Cells and T Follicular Helper Cells Controlling Long-Lived Immunity (D2), April 2017, 2327, Whistler, British Columbia, Canada; Mononuclear Phagocytes in Health,Immune Defense and Disease, 304 May, Austin, Texas, USA;Modeling Viral Infections and ImmunityMAY 2017, 14, Estes Park, Colorado, USA; IntegratingMetabolism and Immunity(E4)292 June, Dublin, Ireland.

The American Association of Immunologists;Clinical Immunology Society ; Indian Immunology Society;IUIS - International Union of Immunological Societies;American Society for Histocompatibility and Immunogenetics.

Track 5:Clinical Genetics

Clinical geneticsis the practice of clinical medicine with particular attention tothe hereditary disorders. Referrals are made togenetics clinicsfor the variety of reasons, includingbirth defects,developmental delay,autism,epilepsy, and many others. In the United States, physicians who practice clinical genetics are accredited by theAmerican Board of Medical Genetics and Genomics(ABMGG).In order to become a board-certified practitioner of a Clinical Genetics, a physician must complete minimum of 24 months of his training in a program accredited by the ABMGG. Individual seeking acceptance intoclinical geneticstraining programs and should hold an M.D. or D.O. degree (or their equivalent)and he/she have completed a minimum of 24 months of their training in ACGME-accredited residency program internal medicine, pediatrics and gynecology or other medical specialty.

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Belgian Society OfHuman GeneticsMeeting 2017 february 17, 2017, Belgium; American College Of Medical Genetics 2017 AnnualClinical GeneticsMeeting march 21-25 2017, phoenix , United States; German Society Of Human Genetics 28th Annual Meeting, Austrian Society ForHuman GeneticsAnd The Swiss Society OfMedical GeneticsCombined Meeting 2017 march 29, 2017 - March 31, 2017, bochum , Germany; Spanish Society OfHuman GeneticsCongress 2017april 25, 2017 - April 28, 2017 madrid , Spain;

Clinical Genetics Associates;Clinical Genetics Society(CGS);The genetic associate;International Conference on Clinical and Medical Genetics;Association for Clinical Genetic Science;The American Society of Human Genetics.

Track 6:Pharmacogenetics

Pharmacogeneticsis the study of inherited genetic differences in drug metabolic pathways which can affect individual responses towards the drugs, both in their terms of therapeutic effect as well as adverse effects. In oncology, Pharmacogenetics historically is the study ofgerm line mutations(e.g., single-nucleotide polymorphisms affecting genes coding forliver enzymesresponsible for drug deposition and pharmacokinetics), whereaspharmacogenomicsrefers tosomatic mutationsin tumoral DNA leading to alteration in drug response.

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Spanish Society OfHuman GeneticsCongress 2017april 25, 2017 - April 28, 2017, madrid , Spain; 8th World Congress onPharmacology, August 07-09, 2017 Paris, France; World Congress onBio therapeutics, May 22-23, 2017, Mexico City, Mexico; 8th World Congress OnPharmacologyAndToxicology, July 24-26, 2017, Melbourne, Australia; German Society Of Human Genetics 28th Annual Meeting, Austrian Society ForHuman GeneticsAnd The Swiss Society OfMedical GeneticsCombined Meeting 2017march 29, 2017 - March 31, 2017 bochum , Germany.

Pharmacogenomics - American Medical Association;Associate Principal Scientist Clinical Pharmacogenetics;European Society of Pharmacogenomics and Personalised Therapy;Genome-wide association studies in pharmacogenomics.

Track 7:Molecular Genetic Pathology

Molecular genetic pathologyis an emerging discipline withinthe pathologywhich is focused in the study and diagnosis of disease through examination of molecules within the organs, tissues or body fluids. A key consideration is more accurate diagnosis is possible when the diagnosis is based on both morphologic changes in tissuestraditional anatomic pathologyand onmolecular testing. Molecular Genetic Pathology is commonly used in diagnosis of cancer and infectious diseases. Integration of "molecular pathology" and "epidemiology" led tointerdisciplinaryfield, termed "molecular pathological epidemiology" (MPE),which representsintegrative molecular biologicand population health science.

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8th World Congress OnMolecular Pathology, June 26-27, 2017 San Diego, USA; 11th International Conference OnSurgical Pathology& Practice, March 27-28, 2017, Madrid, Spain; 13th EuropeanPathologyCongress, Aug 02-03, 2017, Milan, Italy; Embl Conference:Mammalian GeneticsAndGenomics, Heidelberg, Germany, October 24, 2017; Embo|Embl Symposium: TheMobile Genome: Genetic And Physiological Impacts Of Transposable Elements, Heidelberg, Germany, October 10, 2017.

Clinical Pathology Associates Molecular Pathology; Association mapping Wikipedia;Association for Molecular Pathology(AMP);Molecular Pathology - Association of Clinical Pathologists;SELECTBIO - Molecular Pathology Association of India.

Track 8:Gene Mapping

Genomemappingis to place a collection of molecular markers onto their respective positions ongenome.Molecular markerscome in all forms. Genes can be viewed as one special type of genetic markers in construction ofgenome maps, and the map is mapped the same way as any other markers. The quality ofgenetic mapsis largely dependent upon the two factors, the number of genetic markers on the map and the size of themapping population. The two factors are interlinked, and as larger mapping population could increase the "resolution" of the maps and prevent the map being "saturated". Researchers begin a genetic map by collecting samples of blood or tissue from family members that carry a prominent disease or trait and family members that don't. Scientists then isolate DNA from the samples and closely examine it, looking for unique patterns in the DNA of the family members who do carry the disease that the DNA of those who don't carry the disease don't have. These unique molecular patterns in the DNA are referred to as polymorphisms, or markers.

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3rd WorldBio Summit&Expo, Abu Dhabi, UAE, June 19-21, 2017; 9th International Conference onGenomicsandPharmacogenomicsJune 15-16, 2017 London, Uk; Keystone Symposium: Mononuclear Phagocytes in Health,Immune DefenseandDisease, 304 May 2017, Austin, Texas, USA;Molecular Neurodegeneration(course) Hinxton, Cambridge, UK, January 9-14, 2017;

Association for Clinical Genetic Science;Genome-wide association study Wikipedia;Gene mapping by linkage and association analysis NCBI;Gene mapping by linkage and association analysis | Springer Link.

Track 9:ComputationalGenomics

Computational genomics refers to the use of computational and statistical analysis to decipherbiologyfromgenome sequencesand related data, including DNA and RNA sequence as well as other "post-genomic" data. This computational genomics is also known asComputational Genetics. These, in combination with computational and statistical approaches to understanding the function of the genes and statistical association analysis, this field is also often referred to as Computational and Statistical Genetics/genomics. As such, computational genomics may be regarded as a subset of bioinformatics and computational biology, but with a focus on using whole genomes rather than individual genes to understand the principles of how the DNA of a species controls its biology at the molecular level and beyond. With the current abundance of massive biological datasets, computational studies have become one of the most important means to biological discovery.The field is defined and includes foundations in thecomputer sciences,applied mathematics, animation, biochemistry, chemistry, biophysics,molecular genetics,neuroscienceandvisualization. Computational biology is different from biological computation, which is a subfield of computer engineering using bioengineering and biology to build computers, but is similar tobioinformatics.

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Modeling Viral Infections and Immunity,10. MAY 2017, 14, Estes Park, Colorado, USA;Integrating Metabolism and Immunity(E4)292 June, Dublin, Ireland; EMBL Conference:Mammalian GeneticsandGenomics, Heidelberg, Germany, October 24, 2017; EMBO|EMBL Symposium: The Mobile Genome:GeneticandPhysiological Impacts of Transposable Elements, Heidelberg, Germany, October 10, 2017;

American Association of Bio analysts - Molecular/Genetic Testing;ISCB - International Society for Computational Biology;International Society for Computational Biology Wikipedia;Bioinformatics societies OMICtools;Towards an Australian Bioinformatics Society.

Track 10:Molecular Biotechnology

Molecular Biotechnologyis the use of living systems and organisms to develop or to make products, or "any technological application that uses the biological systems, living organisms or derivatives, to make or modify products or processes for specific use. Molecular biotechnology results from the convergence of many areas of research, such as molecular biology, microbiology, biochemistry, immunology, genetics and cell biology. It is an exciting field fueled by the ability to transfer genetic information between organisms with the goal of understanding important biological processes or creating a useful product. The completion of the human genome project has opened a myriad of opportunities to create new medicines and treatments, as well as approaches to improve existing medicines. Molecular biotechnology is a rapidly changing and dynamic field. As the pace of advances accelerates, its influence will increase. The importance and impact of molecular biotechnology is being felt across the nation. Depending on the tools and applications, it often overlaps with the related fields of bioengineering,biomedical engineering, bio manufacturing andmolecular engineering.Biotechnologyalso writes on the pure biological sciences animalcell culture, biochemistry,cell biology, embryology, genetics, microbiology, andmolecular biology.

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8th EuropeanImmunologyConference, June 29-July 01, 2017 Madrid, Spain; World Congress onBio therapeutics, May 22-23, 2017, Mexico City, Mexico;Human Genome Meeting(HGM 2017), February 5-7 2017, Barcelona, Spain;Integrating MetabolismandImmunity (E4), 292 June, Dublin, Ireland.

Biotech Associations - Stanford University;Indian Society of Genetics, Biotechnology Research & Development;Genetics and Molecular Medicine - American Medical Association;Genetics Society of America | GSA, British Society for Genetic Medicine;Heritability in the Era of Molecular Genetics - Association for Psychological science.

Track 11:Genetic Transformation

Genetic Transformationis the genetic alteration of cell resulting from the direct uptake and incorporation ofexogenous genetic materialfrom its surroundings through thecell membrane. Transformation is one of three processes for horizontal gene transfer, in which exogenous genetic material passes from bacterium to another, the other two being conjugation transfer of genetic material between two bacterial cells in direct contact andTransductioninjection offoreign DNAby a bacteriophage virus into thehost bacterium. And about 80 species of bacteria were known to be capable of transformation, in 2014, about evenly divided betweenGram-positiveandGram-negative Transformation" may also be used to describe the insertion of new genetic material into non-bacterial cells, including animal and plant cells.

RelatedMolecular Biology Conferences| Genetics Conferences|Gene Therapy Conferences|Biotechnology Conferences| Immune Cell Therapy Conferences

13th EuropeanPathologyCongress, Milan, Italy; Embl Conference:Mammalian GeneticsAndGenomics, Heidelberg, Germany, October 24, 2017; Embo|Embl Symposium: TheMobile Genome: Genetic And Physiological Impacts Of Transposable Elements, Heidelberg, Germany, October 10, 2017; 2nd World Congress onHuman Genetics&Genetic Disorders, November 02-03, 2017 Toronto, Canada; 9th International Conference onGenomicsandPharmacogenomics, June 15-16, 2017 London, Uk;

American Society of Gene & Cell Therapy: ASGCT;Gene Therapy Societies and Patient Organizations - Gene Therapy Net;European Society of Gene and Cell Therapy (ESGCT);British Society for Gene and Cell Therapy;Gene Therapy - American Medical Association.

Track 12:Genetic Screening

Genetic screenis an experimental technique used to identify and select the individuals who possess a phenotype of interest inmutagenized population. A genetic screen is a type ofphenotypic screen. Genetic screen can provide important information on gene function as well as the molecular events that underlie a biological process or pathway. While thegenome projectshave identified an extensive inventory of genes in many different organisms, genetic screens can provide valuable insight as to how thosegenes function.

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13th EuropeanPathologyCongress, Aug 02-03, 2017, Milan, Italy; 2nd World Congress onHuman Genetics&Genetic Disorders, November 02-03, 2017 Toronto, 27 Canada; 7th International Conference onPlant Genomics, July 03-05, 2017, Bangkok, Thailand; Embl Conference:Mammalian GeneticsAndGenomics, Heidelberg, Germany, October 24, 2017; Embo|Embl Symposium: TheMobile Genome: Genetic And Physiological Impacts Of Transposable Elements, Heidelberg, Germany, October 10, 2017, 10 - 13 May 2017, American Society ofGeneandCell Therapy(ASGCT) 20th Annual Meeting, Washington, DC;

Association for Clinical Genetic Science; Association for Molecular Pathology (AMP);Mapping heritability and molecular genetic associations with cortical;Genetics and Molecular Medicine - American Medical Association.

Track 13:Regulation of Gene Expression

Regulation of Gene expressionincludes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA), and is informally termed gene regulation. Sophisticated programs of gene expression are widely observed in biology, Virtually any step of gene expression can be modulated, fromtranscriptional initiation,RNA processing, and post-translational modificationof a protein. Often, one gene regulator controls another in a gene regulatory network. Any step of gene expression may be modulated, from theDNA-RNA transcriptionstep to post-translational modification of a protein.

RelatedMolecular Biology Conferences| Genetics Conferences|Gene Therapy Conferences|Biotechnology Conferences| Immune Cell Therapy Conferences

7th International Conference onPlant Genomics, July 03-05, 2017, Bangkok, Thailand; EMBO|EMBL Symposium: The Mobile Genome:GeneticandPhysiological Impacts of Transposable Elements, Heidelberg, Germany, October 10, 2017; 10. MAY 2017, 14, Estes Park, Colorado, USA,Modeling Viral Infections and Immunity; 292 June, Dublin, Ireland,Integrating Metabolism and Immunity(E4); MAY 2017, 14, Estes Park, Colorado, USA,Modeling Viral InfectionsandImmunity; 8th EuropeanImmunologyConference, June 29-July 01, 2017 Madrid, Spain; 9th International Conference onGenomicsandPharmacogenomics, June 15-16, 2017 London, Uk;

Gene Therapy Societies and Patient Organizations - Gene Therapy Net;European Society of Gene and Cell Therapy (ESGCT);British Society for Gene and Cell Therapy;Gene Therapy - American Medical Association

Track 14: Cancer Gene Therapy

Cancer is an abnormal growth of cells the proximate cause of which is an imbalance in cell proliferation and death breaking-through the normal physiological checks and balances system and the ultimate cause of which are one or more of a variety of gene alterations. These alterations can be structural, e.g., mutations, insertions, deletions, amplifications, fusions and translocations, or functional (heritable changes without changes in nucleotide sequence). No single genomic change is found in all cancers and multiple changes (heterogeneity) are commonly found in each cancer generally independent of histology. In healthy adults, the immune system may recognize and kill the cancer cells or allow non-detrimental host-cancer equilibrium; unfortunately, cancer cells can sometimes escape the immune system resulting in expansion and spread of these cancer cells leading to serious life threatening disease. Approaches to cancer gene therapy include three main strategies: the insertion of a normal gene into cancer cells to replace a mutated (or otherwise altered) gene, genetic modification to silence a mutated gene, and genetic approaches to directly kill the cancer cells. Pathway C represents immunotherapy using altered immune cells. Another unique immunotherapy strategy facilitated by gene therapy is to directly alter the patient's immune system in order to sensitize it to the cancer cells. One approach uses mononuclear circulating blood cells or bone marrow gathered from the patient.

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Track 15:Genetic Transplantation

Transplantation genetics is the field of biology and medicine relating to the genes that govern the acceptance or rejection of a transplant. The most important genes deciding the fate of a transplanted cell, tissue, or organ belong to what is termed the MHC (the major histocompatibility complex). Genetic Transplantation is the moving of an organ from one body to another or from a donor site to another location on the person's own body, to replace the recipient's damaged or absent organ. Organs and/or tissues that aretransplantedwithin the same person's body are calledauto grafts. Transplants that are recently performed between two subjects of the same species are calledallografts. Allografts can either be from a living or cadaveric source Organs that can be transplanted are the heart, kidneys, liver, lungs, pancreas, intestine, and thymus. The kidneys are the most commonlytransplanted organs, followed by the liver and then the heart. The main function of the MHC antigens is peptide presentation to the immune system to help distinguish self from non-self. These antigens are called HLA (human leukocyte antigens). They consists of three regions: class I (HLA-A,B,Cw), class II (HLA-DR,DQ,DP) and class III (no HLA genes)

RelatedMolecular Biology Conferences| Genetics Conferences|Gene Therapy Conferences|Biotechnology Conferences| Immune Cell Therapy Conferences

8th World Congress onPharmacology, August 07-09, 2017 Paris, France; International Conference onClinicalandMolecular Genetics, Las Vegas, USA, April 24-26, 2017; Aug 02-03, 2017, 13th EuropeanPathologyCongress, Milan, Italy; Embl Conference:Mammalian GeneticsAndGenomics, Heidelberg, Germany, October 24, 2017; 7th International Conference onPlant Genomics, July 03-05, 2017, Bangkok, Thailand.

American society of Transplantation;American Society of Transplant Surgeons: ASTS; Patient associations. Donation and transplantation;American Society of Gene & Cell Therapy ASGCT;Gene Therapy Societies and Patient Organizations - Gene Therapy Net.

Track 16:Cytogenetics

Cytogeneticsis a branch ofgeneticsthat is concerned withstudy of the structure and function of the cell, especially thechromosomes. It includes routine analysis of G-banded chromosomes, othercytogenetic banding techniques, as well as molecular Cytogenetics such as fluorescent in suitable hybridization FISH and comparativegenomic hybridization.

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European Cytogeneticists Association;Association of Genetic Technologists;Association for Clinical Genetic Science;Cytogenetics - Human Genetics Society of Australasia;European Cytogeneticists Association

Molecular Biology 2016

Molecular Biology 2016 Report

2ndWorld Bio Summit & Molecular Biology Expowas organized during October 10-12, 2016 at Dubai, UAE. The conference was marked with the attendance ofEditorial Board Members of supporting journals, Scientists, young and brilliant researchers, business delegates and talented student communities representing more than 25 countries, who made this conference fruitful and productive.

This conference was based on the theme Recent advances in Bio Science which included the following scientific tracks:

Molecular Biology

Microbiology

Analytical Molecular Biology

Bioinformatics

Biochemistry and Molecular Biology

Molecular Biology and Biotechnology

Cancer Molecular Biology

Computational Biology

Molecular Biology of the Cell

Molecular biology of the cardiovascular system

Molecular Biology in Cellular Pathology

Molecular Biology of Diabetes

Molecular Biology and Genetic Engineering

Enzymology and Molecular Biology

Molecular Biology of the Gene

Molecular Genetics - Molecular Biology Conferences

ASCO and Foundation Medicine Announce Collaboration to Help Research Sites Identify Potential Participants for the … – Business Wire (press release)

Posted on June 8, 2017 by Danzig

ALEXANDRIA, Va. & CAMBRIDGE, Mass.--(BUSINESS WIRE)--The American Society of Clinical Oncology, Inc. (ASCO) and Foundation Medicine (NASDAQ: FMI) today announced entry into an agreement to create efficiencies for research sites participating in ASCOs TAPUR Study in identifying potential participants for the study. ASCO is announcing that reports from Foundation Medicines comprehensive genomic profiling (CGP) assays, FoundationOne, FoundationOne Heme and FoundationACT will receive the new optimized for TAPUR reporting designation available to entities that demonstrate reporting of nearly 75% of TAPUR-specific genes in a format that meets criteria established for the TAPUR Study. The TAPUR Study is a first-of its-kind clinical trial designed to evaluate molecularly targeted cancer drugs and collect data on clinical outcomes to learn about additional uses of these drugs outside of indications already approved by the Food and Drug Administration.

As part of this pilot program, Foundation Medicine will use its SmartTrials technology to create reports for TAPUR sites that identify patients who may qualify to participate in the TAPUR Study. SmartTrials is a molecularly-matched, location-specific, clinical trials database that informs physicians about clinical trials to accelerate patient enrollment. Early use of the SmartTrials report by one TAPUR site was associated with a significant increase in patient accrual with the site reporting identification of more than 60 patients whose genomic profiles matched TAPUR drug targets within a few months of implementing the SmartTrials technology. As part of this arrangement, Foundation Medicine will be launching its SmartTrials reporting to an initial pilot set of the TAPUR Studys participating clinical sites.

We are excited to designate Foundation Medicines CGP assays as providing reports that are optimized for TAPUR participation and work with Foundation Medicine to allow TAPUR Sites to incorporate SmartTrials reporting to streamline identification of patients who may qualify for the TAPUR study, said ASCO Chief Medical Officer and TAPUR Study Principal Investigator, Richard L. Schilsky, MD, FACP, FASCO, FSCT. It is our hope that Foundation Medicines unique expertise in genomics will enable many more patients to access investigational therapies through the TAPUR Study clinical trial.

The TAPUR Studys innovative, biomarker-driven design will expand access for patients to innovative new targeted therapies, while enhancing the collective understanding of the genomic basis of cancer biology, said Vincent Miller, M.D., chief medical officer at Foundation Medicine. Applying the SmartTrials reporting to the TAPUR Study can facilitate rapid and accurate patient identification, accelerating patient enrollment.

About the TAPUR Study TheTAPUR Studyis a non-randomized clinical trial that aims to describe the performance (both safety and efficacy) of commercially available, targeted anticancer drugs prescribed for treatment of patients with advanced cancer that has a potentially actionable genomic variant. The TAPUR Study provides approved targeted therapies that are contributed to the program by collaborating pharmaceutical companies, catalogues the choice of genomic profiling test by clinical oncologists and aims to learn about the utility of registry data to develop hypotheses for additional clinical trials.

About ASCO: Founded in 1964, the American Society of Clinical Oncology, Inc. (ASCO) is committed to making a world of difference in cancer care. As the worlds leading organization of its kind, ASCO represents more than 40,000 oncology professionals who care for people living with cancer. Through research, education, and promotion of the highest-quality patient care, ASCO works to conquer cancer and create a world where cancer is prevented or cured, and every survivor is healthy. ASCO is supported by its affiliate organization, the Conquer Cancer Foundation. Learn more at http://www.ASCO.org, explore patient education resources at http://www.Cancer.Net, and follow us on Facebook, Twitter, LinkedIn, and YouTube.

AboutFoundation Medicine Foundation Medicine(NASDAQ:FMI) is a molecular information company dedicated to a transformation in cancer care in which treatment is informed by a deep understanding of the genomic changes that contribute to each patient's unique cancer. The company offers a full suite of comprehensive genomic profiling assays to identify the molecular alterations in a patient's cancer and match them with relevant targeted therapies, immunotherapies and clinical trials.Foundation Medicine'smolecular information platform aims to improve day-to-day care for patients by serving the needs of clinicians, academic researchers and drug developers to help advance the science of molecular medicine in cancer. Foundation Medicines SmartTrials program helps clinical research sponsors design, plan and implement clinical trials using Foundation Medicines oncology knowledge base and physician network. For more information, please visithttp://www.FoundationMedicine.comor followFoundation Medicineon Twitter (@FoundationATCG).

Foundation Medicineand FoundationOneare registered trademarks and SmartTrialsTMis a trademark ofFoundation Medicine, Inc.

ASCO, American Society of Clinical Oncology and TAPUR are trademarks of American Society of Clinical Oncology, Inc.

Cautionary Note Regarding Forward-Looking Statements This press release contains "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995, including, but not limited to, statements regarding the value and performance capabilities of Foundation Medicines comprehensive genomic profiling assays; the ability of CGP and the SmartTrials services to help accelerate clinical trial enrollment; and the ability of a clinical trial, including the clinical trial design, to expand access to therapies or improve cancer care. All such forward-looking statements are based on management's current expectations of future events and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in or implied by such forward-looking statements. These risks and uncertainties include the risk thatFoundation Medicine'sCGP andservices will not be able to identify genomic alterations in the same manner as prior clinical data or prior experience;clinical trial enrollment does not increase in the expected manner; and the risks described under the caption "Risk Factors" inFoundation Medicine'sAnnual Report on Form 10-K for the year endedDecember 31, 2016, which is on file with theSecurities and Exchange Commission, as well as other risks detailed inFoundation Medicine'ssubsequent filings with theSecurities and Exchange Commission.All information in this press release is as of the date of the release, andFoundation Medicineundertakes no duty to update this information unless required by law.

3-D Mammograms And Molecular Breast Imaging Personalized Approaches To Breast Cancer Screening – HuffPost

Posted on June 8, 2017 by Danzig

This article is authored by the Mayo Clinic Center for Individualized Medicine. The mission of the Center is to discover and integrate the latest in genomic, molecular and clinical sciences into personalized care for patients.

A picture is worth a thousand words. While that saying may be true, for the more than 50 percent of all women who have dense breast tissue, a picture from traditional, 2-D mammography may not tell the full story about whether they have breast cancer.

Breast density is like the wolf in sheeps clothing. Both tumors and dense breast tissue appear white on a mammogram. A traditional 2-D mammogram may not distinguish between the two. Thats why mammograms find as few as 40 percent of cancers in women with dense breasts, says Deborah Rhodes, M.D., a Mayo Clinic Breast Clinic physician.

If tumors are obscured by dense tissue on a mammogram, the tumor may go undetected for a year or longer during which time the tumor will grow which is a significant problem when you consider how closely survival from breast cancer is linked to tumor size at diagnosis. If we discover a tumor when it is less than 1 centimeter, that patient has over a 90 percent chance of surviving. If we could reliably find tumors in dense tissue when they are small, more lives could be saved," adds Dr. Rhodes.

In addition to dense breast tissue masking tumors on a mammogram, research has shown that women with dense breast tissue have a higher risk of developing breast cancer. Many states have now passed legislation mandating that women found to have dense breasts on a mammogram be provided with information about the impact of breast density on breast cancer detection and risk.

Because both Minnesota and Arizona have this legislation, and because national guidelines on breast cancer screening differ, Mayo Clinic breast specialists developed consensus guidelines for breast cancer screening in women with dense breasts.

Bringing dense breast tissue into focus - 3-D mammograms and molecular breast imaging (MBI)

In order to provide the best screening to detect breast cancer, Mayo Clinic physicians recommend that women with dense breasts initially have a 3-D mammogram and be given the option to have further screening with molecular breast imaging (MBI).

Dense breast tissue what you should know

Women with dense breast tissue have a higher proportion of dense tissue compared to fatty tissue in their breasts. You can find out whether you have dense breast tissue by talking with your physician and reading your mammogram report.

Factors that lead to women having dense breasts include:

Adjusting the lens researchers work to refine screening tools

Mayo Clinic Center for Individualized Medicine has supported development of molecular breast imaging as an individualized approach to cancer screening and will continue to support research that refines this technology in order to provide patients with dense breast tissue the best care.

Our goal is to identify the best tool to screen for and diagnose cancer at its earliest stages, when it is more treatable. By finding the best individualized care for women with dense breasts, I think we can greatly reduce the number of breast cancers diagnosed when they are already advanced - cancers that were not visible on an x-ray. We have already demonstrated that MBI can detect many cancers including advanced cancers that were not seen on traditional 2-D mammography. Our future research will continue to evaluate the effectiveness of 3-D mammograms and MBI. While this research is ongoing and important, MBI is available now as a tool for women who seek additional screening because they have dense breasts, says Dr. Rhodes.

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3-D Mammograms And Molecular Breast Imaging Personalized Approaches To Breast Cancer Screening - HuffPost

Caris Life Sciences’ Molecular Intelligence Platform Identifies Patients with MSI-High (or Mismatch Repair Deficient … – PR Newswire (press release)

Posted on June 8, 2017 by Danzig

"In the past, anti-neoplastic agents were developed based on the site of origin, such as breast, prostate or lung," said David Spetzler, M.S., Ph.D., M.B.A., President and Chief Scientific Officer of Caris Life Sciences and co-author on the paper. "With our increased knowledge, both of the genetic alterations that drive and sustain tumorigenesis, as well as the down-regulation of the immune system that enables tumors to escape an immune response, we are better positioned than ever to attack cancers based on their molecular profiles and to develop a treatment plan that is tailored to each patient, regardless of tumor origin. The results of this clinical trial demonstrate that this is truly the case. This now opens a new approach to therapy that is exemplified by the recent FDA approval of pembrolizumab for MSI-High or mismatch repair deficient solid tumors the first cancer therapy approved for use based on a biomarker, regardless of tumor type, and the same population evaluated in this study."

The clinical trial evaluated the efficacy of pembrolizumab in advanced MSI-High or MMR-deficient patients. Eighty-six patients, with 12 different tumor types were enrolled. The objective response rate was 53% and the complete response rate was 21%, demonstrating durable responses with pembrolizumab regardless of tumor origin. The investigators concluded that patients with a large number of neoantigens in MMR-deficient cancers made them sensitive to checkpoint inhibition. Researchers also included Caris Molecular Intelligence prevalence data for MSI-High or MMR-deficient tumors. Using next-generation sequencing (NGS) across 24 tumor types, Caris Molecular Intelligence identified patients with MSI-High solid tumors by evaluating more than 7,000 microsatellite regions across approximately 2,200 cases. Patients were considered MSI-High if they had at least 43 altered microsatellite regions, which was determined by comparing NGS results to traditional polymerase chain reaction (PCR) analysis. The Caris NGS platform performed at 95.8% sensitivity and 99.4% specificity.

"The results of this study, along with the FDA approval of pembrolizumab for MSI-High or mismatch repair deficient solid tumors, marks a turning point where precision medicine is now becoming standard of care for all solid tumor patients," said John Marshall, M.D., Chief Medical Officer of Caris Life Sciences. Dr. Marshall is also the Associate Director for Clinical Care for the Georgetown Lombardi Comprehensive Cancer Center and the Chief of the Division of Hematology-Oncology at MedStar Georgetown University Hospital in Washington, D.C. "The Caris CGP+ tumor profiling platform enables more patients to get MSI results because it does not require normal tissue like the PCR assay, therefore making it optimally positioned to assist clinicians in accurately identifying MSI-High patients so that they receive appropriate therapy. In addition, CGP+ assists innovative biopharmaceutical companies and other healthcare organizations develop the next personalized cancer treatments."

The study was a multi-institution clinical trial conducted by academic, medical, government and commercial organizations including Johns Hopkins, Stanford University, Providence Cancer Center, University of Pittsburgh, National Cancer Institute, Ohio State University, West Virginia University Cancer Institute, Memorial Sloan Kettering Cancer Center, Merck & Company, with funding in part by The Lustgarten Foundation for Pancreatic Cancer Research.

About Caris Life Sciences Caris Life Sciences is a leading innovator in molecular science focused on fulfilling the promise of precision medicine through quality and innovation. Caris Molecular Intelligence, the company's Comprehensive Genomic Profiling Plus (CGP+) molecular testing service and the world's leading immunotherapy diagnostic expert, assesses DNA, RNA and proteins, including microsatellite instability (MSI), total mutational load (TML) and PD-L1, to reveal a molecular blueprint to guide more precise and personalized treatment decisions. The ADAPT Biotargeting System, the company's revolutionary and unbiased profiling platform, is currently being utilized for drug target identification, therapeutic discovery and development, fixed tissue-based companion diagnostics, blood-based cancer screening and biomarker identification. Headquartered in Irving, Texas, Caris Life Sciences offers services throughout the U.S., Europe and other international markets. To learn more, please visit http://www.CarisLifeSciences.com.

Media Inquiries: The Ruth Group Kirsten Thomas / Joanna Zimmerman kthomas@theruthgroup.com / jzimmerman@theruthgroup.com Tel: +1-508-280-6592 / +1-646-536-7006

Caris Life Sciences Media Relations & Corporate Affairs CorpComm@carisls.com 214-294-5606

To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/caris-life-sciences-molecular-intelligence-platform-identifies-patients-with-msi-high-or-mismatch-repair-deficient-solid-tumors-more-likely-to-respond-to-immunotherapy-300471334.html

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Caris Life Sciences' Molecular Intelligence Platform Identifies Patients with MSI-High (or Mismatch Repair Deficient ... - PR Newswire (press release)

The Photographer Capturing the New York You’ve Never Noticed – Artsy

Posted on June 8, 2017 by Danzig

While others on the street are staring at their smartphones, King is looking up, capturing the sculptures that ever-so-subtly change the space all around us, uploading the images to his Instagram, collecting them in books (his third, Figures in Stone, is on shelves now) or spotlighting them in exhibitions. His latest show on City Islandwhich sits just off mainland Bronx in the Long Island sound, and where he now lives after spending most of his life in Harlemopened June 2nd.

Our hour-long walking tour begins at a building at 181st Street and Fort Washington Avenue. Most buildings with interesting stone details date back to between 1850 and 1930; this ones smog-stained facade has seen better days, but a line of stone figures had caught Kings attention as he traveled to a nearby renovation job.

Sometimes I feel like these details talk to me, King says. He means it. What else besides a very interesting conversation could keep him photographing for decades? King began his hobby while taking a class on women in photography. His teacher gave an unusual assignment: Capture the image of women he didnt know. King felt too awkward photographing strangers, so turned his camera to women carved in stone instead. I got an A, he said, with a smile.

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The Photographer Capturing the New York You've Never Noticed - Artsy

Australia Proposes New Risk-Based Approach to Medicine Variations – Regulatory Focus

Posted on June 8, 2017 by Danzig

Australia Proposes New Risk-Based Approach to Medicine Variations Posted 08 June 2017 By Zachary Brennan

Australia's Therapeutic Goods Administration (TGA) on Thursday released guidance on a plan to allow companies to make "very low risk" changes to registered medicines after submitting them to TGA and receiving an automated acknowledgement.

"These requests are known as 'notifications' but still require an application to the TGA," the regulator explained. "These lowest risk variations do not require evaluation but legally must still be approved by the TGA before implementation by the sponsor."

TGA says that such a risk-based approach to the management of variations to medicines, which will be only for changes that do not impact the quality, safety or efficacy of a medicine, will reduce regulatory burdens on industry, reduce unnecessary assessment work for TGA and allow for variations to take effect more quickly.

A list of variations that are acceptable for notification only will be developed, TGA adds, noting that it is looking to generally align with European Medicines Agency requirements.

However, changes to Australia'sTherapeutic Goods Act 1989are needed to implement this new notification process, TGA says, noting that it has introduced into Parliament a bill to amend the act, as well as amendments to theTherapeutic Goods Regulations 1990outlining the first set of changes proposed as notifications.

Other upcoming regulatory reforms were also outlined by TGA last September.

Notifications process: requests to vary registered medicines where quality, safety and efficacy are not affected

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Australia Proposes New Risk-Based Approach to Medicine Variations - Regulatory Focus

Topol: ‘Imprecision’ medicine is plaguing healthcare – Health Data Management

Posted on June 8, 2017 by Danzig

The future of precision medicine doesnt lie in some theoretical construct but is here now in the form of digital tools that are currently available to providers and patients alike.

Thats the contention of Eric Topol, MD, director of the Scripps Translational Science Institute and a keynote speaker at Wednesdays opening session of the 2017 AHIP Institute & Expo in Austin, Texas.

However, before healthcare can take full advantage of a personalized approach to healthcare that treats individualsnot populationsthe industry needs to come to terms with its failed ways.

Medicine today is in a pretty sorry stateits sad to admit, and we have to face the problems we have, said Topol, who contends that imprecision is a root cause of the inefficiency and waste in medicine. We have this illusion that we provide such great healthcare in this country, and its so far from the truth.

Despite the billions of dollars spent developing medications, he pointed to the fact that 75 percent of patients who are prescribed the 10 top-selling drugs dont respond to these pharmaceuticals. In addition, Topol noted that the medical error problem in healthcare is profound, representing the third leading cause of death in the United States; in addition, 12 million Americans are misdiagnosed each year. Further, he said that one in four hospitalized patients are harmed while in the care of clinicians.

Were talking about at least $1 trillion of waste per year because of this imprecision of not seeing people as individuals, but rather (using) this population medicine approach, according to Topol. There is no one who is averagethat person doesnt exist.

Leveraging the available technology to understand each human being is where medicine needs to go in the 21st Century, he said. Whats needed is to map the human body, providing a Google Medical Maps equivalent. But, instead of the satellite street view and traffic view, you have the views of the persons phenome, external features, their DNA, RNA proteins, their epigenome, their microbiome and their exposome, added Topol.

According to Topol, mobile technology is the enabler for measuring human physiology. Today, we can use smartphones to accomplish a lot of this understanding of each individual, he said. And, the smartphone will indeed be the hub in the imminent years of medicine because there are sensors for every physiologic metric.

At the same time, Topol insisted that these medicalized smartphones will serve as technological enablers for the democratization of medicine, giving patients control of their own data, which has historically been the exclusive domain of physicians.

Also See: Medicalized smartphones to put health data in hands of patients

One of the mobile devices that Topol is particularly keen on is smartphone ultrasound. You can now get high-quality, high-resolution images through your phone of any part of your body except the brain, because you cant image through the skull, he added.

A cardiologist, Topol said he also uses a portable echocardiogram through his smartphone to monitor a beating heart.

Why would you ever listen to a persons heart with an obsolete stethoscope? he asked. It isnt even a scope. Its a stethophone. This is really a big shakeup in healthcare, and the fact is that most doctors are not using this. Theres only one reason why it isnt being used. It has something to do with the big Rreimbursement.

Health payers are in the drivers seat here, and theres no entity that has the power to change medicine as insurers, so Im hoping they will buy into these really exciting times that we are in, concludes Topol. We have the tools to do it. Hopefully, we have the will to do it.

Nebraska medicine hits transplant milestone – KMTV.com – KMTV – 3 News Now

Posted on June 8, 2017 by Danzig

OMAHA, NE - Nine donors got to meet the nine people who received their kidneys Thursday during the largest living kidney donor chain in Nebraska history at the Nebraska Medical Center.

It was the first time that they met face to face. All nine transplants happened from February 27-March 3.

Many of the patients wanted to donate to a friend or family member but were matched to others on a Board of Hope.

Donating a kidney is one of the most courageous and noble acts a person can do. Sitting among all of you are 9 superheroes willing to donate a kidney to someone they had never met, knowing only that their friend or family member would receive a kidney in return, said Dr. Arika Hoffman, an NMC Transplant Surgeon.

The youngest recipient, 5-year-old Andy Aranda, concluded the chain and got to meet his donor Thursday. His father says hes needed a new kidney since he was 2-months-old.

He loves superheroes and riding bikes. Now, he knows a real life superhero, his donor, Tyler Sturgeon of Cozad, NE.

People like Tyler he shared his life and his organs for another person its a miracle, said Jesus Aranda, Andys father.

Sturgeon signed up to donate to his close friend, Ricky Love, but is excited to know his friend will live longer and so will the vibrant 5-year-old.

I was happy. Thats two people better than one. So I was like part of the exchange absolutely sign me up for it, and being part of nine makes it even a little more exciting, Sturgeon explained.

Previously the largest living-donor kidney chain at NMC was between three people in 2016.

Nebraska medicine hits transplant milestone - KMTV.com - KMTV - 3 News Now

Few know identity of mystery $25M donor to UNLV med school – Las Vegas Review-Journal

Posted on June 8, 2017 by Danzig

The check with yellow strips of paper hiding the signature and address was not the oversized cardboard variety typically produced for such occasions.

But the amount on the pay to line $25 million stole the show at the Nevada Legislature on Monday.

The surprise gift to UNLVs new medical school from an anonymous donor immediately unleashed speculation about the identity of the deep-pocketed contributor with an aversion to publicity. Its a secret that, for now at least, is known to very few.

Mari St. Martin, spokeswoman for Gov. Brian Sandoval, said only a few members of his administration and UNLV representatives know whose name was beneath the yellow strips.

UNLV President Len Jessup is one of them.

I wouldnt accept the gift otherwise, he said. This gift is fantastic and transformational for the medical school. And again, a great example of a public-private partnership and how well that works in Nevada. Were very excited about this gift.

Jessup said both he and Barbara Atkinson, the dean of the UNLV School of Medicine, were personally involved in the cultivation of the gift. He said the relationship has been in the works for a long, long time. He would not disclose if the donor had given to the university in the past.

Matching funds required

In a surprise move Monday morning, the Legislature approved $25 million for the school, which was above and beyond the $21.8 million for 2017-18 and $30.2 million for 2018-19 allocated from the states general fund.

Lawmakers attached a stipulation, however: The money to help pay for construction of the schools planned $100 million medical education building would require the university to raise an equal amount in matching funds.

Those matching funds appeared in the form of a nondescript check just a few hours later, suggesting the donation may have preceded the bill, rather than vice versa.

According to Maria Di Mento, staff writer for the Chronicle of Philanthropy, anonymous gifts especially large ones are more common than people realize.

Once you give a large gift and you attach your name to it, you are inundated, slammed with giving requests from every charity in your city, state and beyond, she said, explaining why many philanthropists choose to remain out of the limelight. There is so much need these days that charities are desperate to know who can help them.

Tax-exempt public institutions like UNLV, on the other hand, generally prefer to have the donors name publicly attached to a gift, as that can help raise money from other wealthy donors, Di Mento said.

We expect a lot more to come

UNLV School of Medicine Dean Barbara Atkinsons original goal was to find a mega, $100 million donor by the close of the 2017 Legislative session. But she and Jessup both indicated that the sudden appearance of half that amount is a big step forward.

This very successfully kicks off the fundraising for the school of medicine facility, Jessup said. We expect a lot more to come.

Atkinson agreed, and said she wasnt concerned that the donor preferred to remain anonymous.

Im not worried about that, she said. There are a lot of people who give anonymous gifts. There are a lot of people who want to help and are very passionate about doing something that will make a difference, and they dont want their names out there.

She added that the UNLV Foundation, which will hold the money until the full amount for the schools building is raised, would not have presented the check to the governor without proper vetting.

While Board of Regents Chairman Rick Trachok said he didnt know the donors name, he had full confidence that the gift is from a highly respectable source.

For institutions of higher education, donors can sometimes be swayed to go public in exchange for naming rights for a building, a classroom wing or a department, Di Mento said.

While such considerations were not important to this donor, Atkinson said, the school is still looking for two others who would like to leave their marks on the new program one willing to put up the remaining $50 million for the new medical education building and one for the entire School of Medicine.

A potential liability

While many donors choose to remain publicly anonymous, most high-profile charities and tax-exempt public institutions are unwilling to accept a donation without knowing who was behind the gift, Di Mento said.

It could be a real liability to them (the nonprofit), she said.

Marc Owens, a partner with Loeb & Loeb, an international law firm with headquarters in Los Angeles, California, said he has facilitated anonymous contributions on a handful of occasions. He said such donors generally act out of pure altruism.

The donor truly doesnt want any public recognition, but feels an intense desire to support a particular charity, he said, adding that some donors dont even want the gift to be publicized.

According to Ellis Carter, managing law partner for the Caritas Law Group in Seattle, some go to great lengths to hide their identity, such as giving money through a donor-advised fund or a community foundation that can then re-grant it to the targeted charity in this case UNLVs Medical School.

Owens said the Internal Revenue Service doesnt have a problem with anonymous donations, and that there is no duty for the agency to investigate the source of such a gift.

However, he said there are risks for any institution that accepts a gift without knowing the source if, for example, it comes to light that it came from a criminal or a person with a bad reputation. He recalled such a scenario in the wake of the Enron scandal.

You had universities scrambling to rename buildings that were named after perpetrators of the Enron fraud, Owens said.

While anonymous donors are shy about publicity, they generally dont balk at taking the tax deduction that goes with a charitable contribution, Owens said.

He says a thank-you letter to the secret UNLV donor has likely already been penned by someone within the state government the proof necessary to claim such a write-off from the federal government.

Contact Natalie Bruzda at nbruzda@reviewjournal.com or 702-477-3897. Follow @NatalieBruzda on Twitter.

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Few know identity of mystery $25M donor to UNLV med school - Las Vegas Review-Journal

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Monthly Archives: June 2017

NASA had a record pool of 18000 applicants to be an astronaut. These 12 made it. – USA TODAY

NASA’s Mars Rover concept looks like the ultimate extraterrestrial golf cart – GolfDigest.com

Two 2017 NASA Astronaut Candidates have ties to Hampton Roads – wtkr.com

NASA’s Asteroid-Hunting NEOWISE Discovers Trove of 114 Objects (Video) – Space.com

Americans ‘under siege’ from climate disinformation former Nasa chief scientist – The Guardian

Nanotechnology reveals hidden depths of bacterial ‘machines’ – Phys.Org

NSF Announces 2017 Winners for Generation Nano: Small Science, Superheroes – Controlled Environments Magazine

College, Grad School, and Post Doc Opportunities | Nano

UQ, partners taking computing out of this world – Phys.org – Phys.Org

Scholar Spotlight: Using Nano Technology, Amay Bandodkar Creates Self-Healing Wearable Devices – MilTech

A new way to extend Moore’s law – The Economist

Molecular Genetics – Molecular Biology Conferences

ASCO and Foundation Medicine Announce Collaboration to Help Research Sites Identify Potential Participants for the … – Business Wire (press release)

3-D Mammograms And Molecular Breast Imaging Personalized Approaches To Breast Cancer Screening – HuffPost

Caris Life Sciences’ Molecular Intelligence Platform Identifies Patients with MSI-High (or Mismatch Repair Deficient … – PR Newswire (press release)

The Photographer Capturing the New York You’ve Never Noticed – Artsy

Australia Proposes New Risk-Based Approach to Medicine Variations – Regulatory Focus

Topol: ‘Imprecision’ medicine is plaguing healthcare – Health Data Management

Nebraska medicine hits transplant milestone – KMTV.com – KMTV – 3 News Now

Few know identity of mystery $25M donor to UNLV med school – Las Vegas Review-Journal