Monthly Archives: February 2014

Comets edge Iowa on goal in ninth round of AHL shootout

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DES MOINES, Iowa The Utica Comets won in a truly wild finish, as they defeated the Iowa Wild, 3-2, in a shootout at Wells Fargo Arena in Des Moines.

Alex Biega won the game in the ninth round with his first shootout goal this season, and goaltender Joe Cannata put together a career-high 43 saves as he earned his fifth victory as a Comet.

The Comets took an early lead in the shootout when Jeremy Welsh converted on his first attempt of the season in the opening round. After a Phillips goal in the third round and a Connolly goal in round seven, Patrick Mullens shot trickled across the line to keep the Comets alive. After the two teams traded misses, Biega ended the game in the ninth round as he snapped a shot past Curry to secure the two points.

Nicklas Jensen and Colin Stuart each found the back of the net during regulation for Utica, which moved to 17-22-2-4 on the season.

The visitors got off to a shaky start as Iowa center Carson McMillan scored his team leading 11th goal of the season to put the Wild ahead by one, 6:17 into the game. Jon Blum also picked up an assist on the play, his 18th of the season.

Utica came right back to knot the score at one as Jensen found the back of the net for the second straight game, with a power-play goal at the 14:44 mark of the first with his 36th point of the season.

A series of firsts gave Utica its only regulation lead of the evening with just 42 seconds left in the first period. Stuart deflected a shorthanded Welsh shot past Iowa netminder Jonas Gustafsson to make it 2-1 which was also the first shorthanded goal Utica has scored this season that hasnt come on an empty net. Welshs assist was his first point as a Comet, as well.

The tying score from the Wild came though when Zach Phillips scored a power-play goal from the slot.

Defenseman Steven Kampfer recorded the primary assist, his eighth of the season, while Landry netted his second point of the night on the play.

A back and forth third period did not result in any goals and the Wild would head to overtime for their sixth straight game and 14th overall.

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Comets edge Iowa on goal in ninth round of AHL shootout

Psoriasis: Symptoms, Pictures, Causes, and Treatments

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Psoriasis is a chronic skin disease characterized by red patches on the skin, often accompanied by silvery-white scales of dead skin cells. It is not contagious.

Psoriasis is believed to be an autoimmune disease, meaning the body's defense system attacks healthy cells in the body. This creates skin cells that mature and die in less than a week, which is extremely rapid considering normal skill cells mature and replace dead ones usually in a month's time.

The buildup of dead cells on the skin's surface is called plaque. While these can occur anywhere on the body, they are more common in the following areas:

The National Psoriasis Foundation estimates that as many as 7.5 million Americans and 125 million people worldwide (about 2.2 percent of the population) have psoriasis, making it the most prevalent autoimmune disease in the world.

While psoriasis affects the skin, it goes beyond a cosmetic problem. The exterior symptoms of psoriasis can affect a person's self-esteem and personal image, which can create problems in their everyday lives such as anxiety and alienation.

There are several different types of psoriasis, distinguished by 1) the affected area of the body and 2) the type of patches. They include:

This type involves plaques on the scalp that typically can be confused as dandruff. About half of all people with any type of psoriasis also have scalp psoriasis.

Found anywhere on the body, plaque psoriasis is the most common form of psoriasis. Small red bumps spread and dead skin cells easily flake from those areas.

This type of psoriasis involves smooth inflamed lesions in areas where the skin folds or flexes, such as the armpits, groin, or under the breast.

This kind causes severe disruption to the body's chemical balance, affecting the majority of the body, and causes symptoms such as severe scaling, pain, and itching to the point where the skin looks as though it has been burned. It can also cause severe illness.

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Psoriasis: Symptoms, Pictures, Causes, and Treatments

Systemic Psoriasis Therapeutics in Major Developed Markets to 2020 – Continued Uptake of Biologics and Novel Pipeline …

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Albany, NY (PRWEB) February 06, 2014

Systemic Psoriasis Therapeutics in Major Developed Markets to 2020 - Continued Uptake of Biologics and Novel Pipeline Drugs to Drive Growth Description

Research has released its pharma report Systemic Psoriasis Therapeutics in Major Developed Markets to 2020 - Continued Uptake of Biologics and Novel Pipeline Drugs to Drive Growth. The systemic psoriasis market is forecast to grow substantially over the forecast period from $5.0 billion in 2013 to $10.4 billion in 2020, across the eight major markets. This growth will be driven by a rising treatment population and the continued uptake of biologics. Biologics will continue to drive market growth despite leading brands Enbrel (etanercept), Humira (adalimumab) and Remicade (infliximab) losing patent protection in most of the major markets over the forecast period. Although the market will suffer revenue losses as a result of sales erosion from biosimilar competitors, this will be offset by the emergence of novel therapies. Most notably, these include monoclonal antibodies secukinumab, ixekizumab and brodalumab, which are currently being developed by Alcon (Novartis subsidiary), Eli Lilly and Amgen, respectively.

To Buy The Copy of This Report Visit: http://www.marketresearchreports.biz/analysis/186872

Scope

An introduction to psoriasis, which includes symptoms, epidemiology, etiology, pathophysiology, diagnosis and treatment Analysis of the major systemic therapies in the current psoriasis marketed landscape Analysis of the pipeline for psoriasis, which includes a breakdown of pipeline molecules by phase of development, molecule type, molecular target and novelty. Psoriasis clinical trials are analyzed by size, duration and failure rates, and a comparative analysis of the most promising systemic pipeline molecules is also provided. Forecast projections for the systemic psoriasis market to 2020. Analysis is provided for the global market and each of the eight major markets. The forecast incorporates projected, low and high variance scenarios based on treatment usage patterns and annual therapy costs in each of the major markets. Analysis of strategic consolidations, including co-development and licensing deals, within the psoriasis indication

Reasons to Buy

Understand the current systemic psoriasis marketed products landscape and recognize the dominant therapeutic agents and pharmaceutical players involved Identify trends and developments within the psoriasis pipeline and consider how the future competitive environment will be impacted Consider market opportunities and potential risks by examining the psoriasis clinical trial landscape in relation to industry averages Observe projections for treatment usage patterns, annual therapy costs and market growth in the eight major markets and understand reasons for variance in projected patterns of growth in the eight major markets

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Tests That Diagnose Psoriatic Arthritis

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By Bethany Afshar WebMD Feature

If you are one of the 7 million people in the United States who have the skin condition psoriasis, you should know the signs and symptoms of psoriatic arthritis. As many as 40 percent of people with psoriasis also have psoriatic arthritis.

The causes of psoriasis and psoriatic arthritis are not completely understood. Genetics, the environment, and your immune system are all thought to play roles. Some scientist believe that your immune system attacks your skin when you have psoriasis. When you have psoriatic arthritis, it attacks the joints, causing inflammation.

It can be hard to find out you have psoriatic arthritis. There are no significant tests that can be done to support diagnosis. Doctors must exclude other types of arthritis, and patients must have a history of psoriasis or have active psoriasis to get the diagnosis, says Erin Boh, MD, chairman of dermatology at Tulane University Health Sciences Center in New Orleans.

Your joint symptoms may be mild, so your doctor may suspect other typical causes of pain, says Eric Matteson, MD, rheumatology chair at Mayo Clinic in Rochester, MN.

The first symptoms may not seem related to your skin condition, Matteson says. But that stiffness in your back may be caused by spine inflammation. Its important to get a correct diagnosis so that you can be treated before your joints have permanent damage.

The condition can develop very slowly. In most cases, a person will develop or have psoriasis before he has signs of psoriatic arthritis.

In the less common cases where joint problems show up before the skin symptoms, it can be even more difficult to diagnose. When it does affect the joints of the arms and legs, it can cause swelling that looks like rheumatoid arthritis and be confused with this disease, Matteson says.

Your doctor will ask you questions about your medical and family histories, as well as examine you for swollen and tender joints. You may have an X-ray to see if you have joint damage, and blood tests can help rule out other diseases.

Skin specialists, known as dermatologists, are often the first to suspect psoriatic arthritis in people theyre treating for psoriasis.

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Tests That Diagnose Psoriatic Arthritis

World Travel Radio with Phil Blizzard – "The Billionaire Lifestyle Experience" – Video

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World Travel Radio with Phil Blizzard - "The Billionaire Lifestyle Experience"
Travel presenter Phil Blizzard looks at the "Billionaire Lifestyle Experience" - a three-week long holiday with guests staying across the world in 10 of the ...

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eTravel World at ITB: The stage is set for big data, mobile solutions and social media

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eTravel World joins Travel Technology under one roof in Hall 6.1 for the first time international companies' latest trends and innovations occupy a larger display area leading eTravel experts host workshops, papers and discussions on up-to-the- minute topics

Berlin, 6 February 2014 Travel experts must acquire the necessary knowledge to keep abreast of the latest technological developments and their impact on the tourism industry. Travel technology is a key market and the eTravel World at ITB Berlin provides all the latest information. A fast-growing segment, the eTravel World has now moved to the Travel Technology Hall (6.1). Thus the world's leading travel trade show has combined this market with exhibitors of traditional technology, which can now be found next door in Hall 5.1. In Hall 6.1 the eTravel World will gain an extra 50 per cent of floor space and a larger stage, enabling it to meet the growing demand.

One of the most pressing issues which experts holding three lectures will be discussing is that of secure communications. On 5 March experts from Secusmart and Sophos will be giving papers on "Bug-proof mobile communications" and "Bring Your Own Device" respectively. On 7 March the software manufacturer SAP will be talking about the "The cloud". Big data is another key topic.

On 6 March, for the first time, ITB Berlin and the International Federation for Information Technologies in Travel and Tourism (IFITT) will be co-organising a two-hour workshop (IFITT@ITB). International experts will be discussing "E-tourism social media and big data: In search of competitiveness". Prof. Dimitri Buhalis will moderate the event. The workshop will highlight the potential of business intelligence and data mining for the travel and tourism industry. The panel members are Prof. Dimitrios Buhalis, University of Bournemouth, UK; Prof. Wolfram Hpken, Hochschule Ravensburg-Weingarten, Germany and Prof. Matthias Fuchs, Mid-Sweden University, Sweden.

On 7 March, a panel discussion involving Traveldudes, Reiseblogger Kollektiv, DZT and hberlein & maurer will be debating "Social media monitoring" and "Return on investment". More and more bloggers, agencies and destinations are collaborating with each other. At a number of lectures and discussion rounds Germany's most successful bloggers, including Anja Beckmann (travelontoast.de), will be explaining how working together can benefit all parties concerned. Furthermore, on the days reserved for trade visitors and on the Saturday of the show, taking place on the eTravel Stage, professional travel bloggers will be presenting travel destinations, among them Sebastian Canaves (offthepath.com) and Laurel Robbins (monkeyandmountains.com).

Innovations which could kickstart a future trend and practical tips

Everyone is eagerly awaiting innovations which could kickstart a future trend. On 6 March mattheis.werbeagentur will be presenting "Gamification in tourism". On 7 March SITA, an IT company, will be demonstrating "Wearables" and Ray Sono, an internet agency, will be presenting "Responsive Design". On 5 March iBusiness will be debating the issue of how much web and app developments really cost. On 7 March Routerank will be discussing the possibilities for planning door-to-door travel.

On 5 March Tourismuszukunft will be providing visitors with valuable practical knowledge and discussing best cases with members of the audience. Videos will also serve to highlight the topic of brand engagement. On 5 and 6 March respectively, Eduardo Perrez and BrandEngage will be showing how to implement the necessary tools to achieve success.

Guided tours offer expert help

For the first time at the show, ITB Berlin and Tourismuszukunft will be co-organising tours to guide visitors around Travel Technology. The tours will focus on software for the hotel industry, destinations and tour operators. A Mobile Technology tour will also be on offer. The tours will be taking place on 5 and 7 March. Participation is free for trade visitors and journalists, who must register in advance. Those wishing to take part in the tours can register at http://www.itb-berlin.com/traveltechnology. Furthermore, there will be networking events taking place on each of the three days reserved for trade visitors, including events sponsored by Expedia, Sojern and the media partners Touristiklounge and TNOOZ. Other sponsors of the Travel World include B2Perfomance, Cityhook, Mappingmaster, Michael Mller Verlag, Thoughtworks, Touristiklounge and Neofonie.

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eTravel World at ITB: The stage is set for big data, mobile solutions and social media

Ten Ways Facebook Has Changed How We Travel

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This week is Facebook's 10th Anniversary, and all I can say is that in the past decade the world's largest social network sure has changed the way we travelboth for better and for worse. From my perspective, here are ten of the biggest changes:

Our travel dreams feel more achievable. When you log onto Facebook and see a friend riding a camel through the Sahara or photographing penguins in Antarctica, it becomes easier to picture yourself there. It also makes you insanely jealous.

We spend more time savoring our upcoming vacations. As soon as we announce travel plans on Facebook, we start to discuss them with friends and daydream about the trip. And happiness experts will tell you that the more time you spend anticipating a happy event, and reveling in that anticipation, the more it boosts your happiness.

It's easier to get our friends' recommendations for destinations we're headed to. Do a Facebook search for, say, "Hotels in Los Angeles," and you can immediately learn which of your friends have been to which hotels there, which they liked most, and what they have to say about them. It's a lot faster than emailing individual people whom you seem to recall may have once visited the place.

We share our travel experiences in real time. In the old days you had to wait for your neighbors to get back from a trip before you could see their photos. Now you see them atop the Eiffel Tower at the moment they're there.

We're forced to choose hotels with free Wi-Fi. Because if you can get on Facebook for free at home, you feel like an idiot paying a daily fee of $9.99or, in some countries, $29.99for Internet access.

When we're hungry or need a sightseeing break, we're drawn to eateries with Wi-Fi so we can "check in" on Facebook and check our friends' updates. Which is sad because when you're traveling you should seek out homegrown hangouts, not Starbucks. The more you spend those spare moments connecting with people you already know, the less you'll connect with locals.

We can track where we've been via Facebook's Timeline. It's now Facebook, not the attic, where we store our personal travel diaries and photo albums. And we carry our trip memories with us at all timeson our smartphones.

We're less likely to get homesick. No matter where you are in the world, you can keep constantly connected with friends and family back home.

We're more likely to worry throughout a trip that our house is being robbed. It's a risk you run when you announce on Facebook that you're hundreds of miles from home.

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Ten Ways Facebook Has Changed How We Travel

What Is Stem Cell Treatment? | eHow – eHow | How to Videos …

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Bronwyn Timmons

Based in Colorado, Bronwyn Timmons has been writing professionally since 2009. Her work has appeared on a variety of websites, covering topics such as career and education planning, wedding planning, home improvement, crafts and gardening. Timmons is pursuing her bachelor's degree in mortuary science.

Stem cell research is on the rise, giving hope to patients and providing treatment for many diseases and disorders. While stem cell treatments are a fairly new science, they can have life-saving effects.

Stem cell treatments consist of removing healthy regenerative cells from the patient and transplanting them into the affected area. This treatment helps repair and reverse a variety of conditions and diseases.

Regenerative cells can be harvested from the patient's bone marrow, fat or peripheral blood. This is done to eliminate the risk of cell rejection in the patient.

Typically, four to six treatments are administered depending on how the condition reacts to the stem cell treatment. Treatments are given over a period of seven to 12 days.

Stem cell treatments are effective at treating autoimmune diseases, cerebral palsy, degenerative joint disease, multiple sclerosis, osteoarthritis, rheumatoid arthritis, spinal injuries and type 2 diabetes. It is thought that in the future, stem cell treatment can be used to treat Alzheimer's disease.

Stem cell therapy can reduce pain and discomfort; it can help patients suffering from arthritis regain mobility. In serious cases, such as cerebral palsy and multiple sclerosis, stem cell treatments can be life-saving.

Because stem cell treatment is a new science, little is known about its long term effects. According to Cell Medicine, no side effects have been reported by patients other than pain at the injection site.

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Stem Cell Therapy for Feline Kidney Disease, a Video Testimonial by a Pleased Pet Owner Gives Hope for Cats Suffering …

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Poway, CA (PRWEB) February 06, 2014

Stem Cell Therapy for Feline Kidney Disease is a special interest piece produced by Nicky Sims, the owner of Kitters, who recently had Vet-Stem Regenerative Cell Therapy for his Feline Kidney Disease. Nicky highlights Kitters journey through diagnosis of the disease and his recent stem cell therapy, as well as educating about stem cells and their benefits.

Nickys film explains that Kitters began showing signs of kidney failure at the age of 15, exhibiting classic symptoms; lack of appetite, excessive thirst, nausea and lethargy. In 2012, Kitters was officially diagnosed with Chronic Renal Failure, or kidney disease. He was prescribed a low protein diet and subcutaneous fluids for rehydration. This has been the standard treatment for decades although it has only been shown to slow the progression of the disease; not reverse it.

Dr. Richter at Montclair Veterinary Hospital thinks that there is something else that can help. In recent years, his hospital has begun using stem cells to treat animals for various orthopedic conditions such as pain from arthritis and dysplasia. In October 2013, Kitters would be the first cat he had treated with stem cell therapy for Feline Kidney Disease.

Dr. Richter explains why this could work for Kitters, Stem cells are cells within your body that are able to turn into any other cell in the body. Kitters has kidney issues, so what weve done is harvested some fat from his abdomen and sent that fat to Vet-Stem in San Diego, and what they do is isolate the stem cells from the fatty tissue. They concentrate them and send them back to us. In the case of an animal with kidney disease, we just give the stem cells intravenously. What that is going to do is begin the healing and rebuilding process.

Nickys film explores the importance of kidneys stating they play a vital role, ridding the body of toxins. As kidney disease progresses scar tissue develops making it harder to filter toxins. Damage to the kidneys makes the animal vulnerable to a number of other health conditions. Unfortunately the disease usually goes undiagnosed given that the symptoms of the disease often do not show until 2/3 of the kidneys are damaged.

Kitters own stem cells were used with the hope of repairing his damaged tissue Dr. Richter goes on, The nice thing about stem cells is that there is no issue of tissue rejection, since it is Kitters own stem cells. Additionally, if there is anything else going on in his body beyond the kidneys its going to address that as well. So, it is a really wonderful systemic treatment.

To find out more or view the special interest piece by Nicky Sims, Stem Cell Therapy for Feline Kidney Disease, visit this link.

About Vet-Stem, Inc. Vet-Stem, Inc. was formed in 2002 to bring regenerative medicine to the veterinary profession. The privately held company is working to develop therapies in veterinary medicine that apply regenerative technologies while utilizing the natural healing properties inherent in all animals. As the first company in the United States to provide an adipose-derived stem cell service to veterinarians for their patients, Vet-Stem, Inc. pioneered the use of regenerative stem cells in veterinary medicine. The company holds exclusive licenses to over 50 patents including world-wide veterinary rights for use of adipose derived stem cells. In the last decade over 10,000 animals have been treated using Vet-Stem, Inc.s services, and Vet-Stem is actively investigating stem cell therapy for immune-mediated and inflammatory disease, as well as organ disease and failure. For more on Vet-Stem, Inc. and Veterinary Regenerative Medicine visit http://www.vet-stem.com or call 858-748-2004.

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Stem Cell Therapy for Feline Kidney Disease, a Video Testimonial by a Pleased Pet Owner Gives Hope for Cats Suffering ...

Histones may hold the key to the generation of totipotent stem cells

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5 hours ago This image shows iPS cells (green) generated using histone variants TH2A and TH2B and two Yamanaka factors (Oct3/4 and Klf4). Credit: RIKEN

One major challenge in stem cell research has been to reprogram differentiated cells to a totipotent state. Researchers from RIKEN in Japan have identified a duo of histone proteins that dramatically enhance the generation of induced pluripotent stem cells (iPS cells) and may be the key to generating induced totipotent stem cells.

Differentiated cells can be coaxed into returning to a stem-like pluripotent state either by artificially inducing the expression of four factors called the Yamanaka factors, or as recently shown by shocking them with sublethal stress, such as low pH or pressure. However, attempts to create totipotent stem cells capable of giving rise to a fully formed organism, from differentiated cells, have failed.

The study, published today in the journal Cell Stem Cell and led by Dr. Shunsuke Ishii from RIKEN, sought to identify the molecule in the mammalian oocyte that induces the complete reprograming of the genome leading to the generation of totipotent embryonic stem cells. This is the mechanism underlying normal fertilization, as well as the cloning technique called Somatic-Cell Nuclear Transfer (SCNT).

SCNT has been used successfully to clone various species of mammals, but the technique has serious limitations and its use on human cells has been controversial for ethical reasons.

Ishii and his team chose to focus on two histone variants named TH2A and TH2B, known to be specific to the testes where they bind tightly to DNA and affect gene expression.

The study demonstrates that, when added to the Yamanaka cocktail to reprogram mouse fibroblasts, the duo TH2A/TH2B increases the efficiency of iPSC cell generation about twentyfold and the speed of the process two- to threefold. And TH2A and TH2B function as substitutes for two of the Yamanaka factors (Sox2 and c-Myc).

By creating knockout mice lacking both proteins, the researchers show that TH2A and TH2B function as a pair, are highly expressed in oocytes and fertilized eggs and are needed for the development of the embryo after fertilization, although their levels decrease as the embryo grows.

In the early embryo, TH2A and TH2B bind to DNA and induce an open chromatin structure in the paternal genome, thereby contributing to its activation after fertilization.

These results indicate that TH2A/TH2B might induce reprogramming by regulating a different set of genes than the Yamanaka factors, and that these genes are involved in the generation of totipotent cells in oocyte-based reprogramming as seen in SCNT.

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Histones may hold the key to the generation of totipotent stem cells

Extraordinary stem cell method tested in human tissue

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(Image: Charles Vacanti and Koji Kojima, Harvard Medical School)

Talk about speedy work. Hot on the heels of the news that simply dipping adult mouse cells in acid could turn them into cells with the potential to turn into any cell in the body, it appears that the same thing may have been done using human cells.

The picture above, given to New Scientist by Charles Vacanti at Harvard Medical School, is said to be images of the first human "STAP cell" experiments.

Last week, the scientific world was bowled over by a study in Nature showing that an acidic environment turned adult mouse cells into "totipotent" stem cells which can turn into any cell in the body or placenta. The researchers called these new totipotent cells stimulus-triggered acquisition of pluripotency (STAP) cells.

"If they can do this in human cells, it changes everything," Rob Lanza of Advanced Cell Technologies in Marlborough, Massachusetts, said at the time. The technique promises cheaper, quicker and potentially more flexible cells for regenerative medicine, cancer therapy and cloning.

Now, Vacanti and his colleagues say they have taken human fibroblast cells and tested several environmental stressors on them in an attempt to recreate human STAP cells. He won't reveal what type of stressors were applied but he says the resulting cells appears similar in form to the mouse STAP cells. His team is in the process of testing to see just how stem-cell-like these cells are.

Vacanti says that the human cells took about a week to resemble STAP cells, and formed spherical clusters just like their mouse counterparts. Using a similar experimental set-up with green monkey (Chlorocebus sabaeus) cells, Vacanti says the resulting cells are behaving slightly differently. He says that may be due to the fact that the researchers used slightly different techniques. Both Vacanti and his Harvard colleague Koji Kojima emphasise that these results are only preliminary and much further analysis and validation is required.

"Even if these are STAP cells they may not necessarily have the same potential as mouse ones they may not have the totipotency which is one of the most interesting features of the mouse cells," says Sally Cowley, head of the James Martin Stem Cell Facility at the University of Oxford.

Pluripotent cells, such as embryonic stem cells, can form any cell in an embryo but not a placenta. Totipotent cells, however, can form any cell in an embryo and a placenta meaning they have the potential to create life. The only cells known to be naturally totipotent are in embryos that have only undergone the first couple of cell divisions immediately after fertilisation.

Research using totipotent cells would have to be under very strict regulatory surveillance, says Cowley. "It would actually be ideal if the human cells could be pluripotent and not totipotent it would make everyone's life a lot easier."

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Extraordinary stem cell method tested in human tissue

Spirituality "Spirit Science" Extraterrestrial Life, ET’S Life In The Universe (Chapter Thirteen) – Video

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Spirituality "Spirit Science" Extraterrestrial Life, ET #39;S Life In The Universe (Chapter Thirteen)
Download #39;Life In The Universe #39; FREE: http://newmessage.us1.list-manage1.com/subscribe?u=b62a83aa674e68545ee781bae id=dcad5d2980 Life In The Universe:- For t...

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