Do You Want To Know Your DNA's Secrets?

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NEAL CONAN, HOST:

This is TALK OF THE NATION. I'm Neal Conan, in Washington. A process that took squadrons of scientists several years and billions of dollars may soon be part of medical routine. Recent advances now make it possible to unravel a person's complete genetic code in a matter of weeks, for roughly about the cost of an MRI.

Doctors can use that genome sequence to help diagnose and treat patients with mysterious or hidden conditions. But these advantages come with questions, too, about ethics, about accuracy, about usefulness and about costs. So what do you want to know from your genetic code? Give us a call: 800-989-8255. Email us: talk@npr.org. You can also join the conversation on our website. That's at npr.org. Click on TALK OF THE NATION.

Later in the program, President Bill Pullman, from "Independence Day" to "1600 Penn." But first, NPR's science correspondent Rob Stein joins us here in Studio 3A.

Nice to have you back on TALK OF THE NATION, Rob.

ROB STEIN, BYLINE: Oh, nice to be here, Neal.

CONAN: And what's driving this speed-up in the genetic code process?

STEIN: Yeah, it's really been kind of a revolution in the ability to decode the genetic code. It wasn't that long ago that, as you said, it took hundreds of scientists, and it cost something like $3 billion just to get a rough draft of the first genetic blueprint. And what's happened over the last 12 years or so is that technology's really gone kind of crazy, and it's a combination of computing power and new techniques for - in optics and some chemical processes that can really speed up the process unbelievably.

And now it can take, as you said, a matter of weeks, and there is even some talk that there's some new techniques that could bring it down to just a matter of days, or even hours, potentially.

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Do You Want To Know Your DNA's Secrets?

Posted in DNA

IntegenX Announces U.S. Launch of the RapidHIT™ 200 System – Rapid DNA Technology That Will Revolutionize the Use of …

SAN DIEGO & PLEASANTON, Calif.--(BUSINESS WIRE)--

IntegenX Inc., a leading developer of rapid human DNA identification technology, today announced the commercial availability of its RapidHIT 200 Human DNA Identification System in the U.S. at the 2012 International Association of Chiefs of Police Conference and Exposition in San Diego, California. Representatives from IntegenX are on site at the meeting to demonstrate the self-contained desktop system, which is the first commercially available rapid DNA device.

Rapid DNA analysis is a transformative technology that promises to fundamentally change the way investigations are conducted by enabling law enforcement personnel to quickly and definitively link a suspects DNA to a crime scene, or eliminate suspicion, all while the suspect is still in police custody.

The RapidHIT 200 System provides actionable intelligence by automating and accelerating the process of producing standardized DNA profiles from cheek swabs in about 90 minutes. This is compared to a process that currently takes up to eight instruments and at least a day in a specialized lab, with results typically returned to police in weeks to months.

Stevan Jovanovich, President and Chief Executive Officer of IntegenX commented: The availability of this technology now will revolutionize the use of DNA in law enforcement. We see the implementation of rapid DNA as reinforcing the partnership between crime labs and police putting more power in their hands to get DNA results faster. Law enforcement agencies have been waiting a long time for this capability. We are proud to be the first to deliver it and to say Rapid DNA is here!

Numerous international law enforcement and security agencies use DNA-based human identification to make informed decisions regarding the arrest, detention or release of suspects, as well as to analyze crime scene evidence. By integrating what was until now a multi-step, multi-system process, rapid DNA technology has the potential to accelerate and expand the use of proven DNA technologies to help the efforts of law enforcement, homeland security, and defense to create safer communities and a safer world.

One of the first police departments to place an order for the RapidHIT 200 System is Palm Bay, Florida, an organization known for its progressive use of DNA to solve high volume crimes.

We are extremely proud of what we have been able to accomplish so far using DNA, and expect the RapidHIT 200 System to greatly accelerate our efforts, said Doug Muldoon, Police Chief of Palm Bay. Based on our experience, the more we can use this ultimate identification tool in our work, the more our crime rates go down and our case closure rates go up. That is good news for creating safer communities for our citizens. Rapid DNA will enhance our methods for dealing with high volume crimes using our locally created database.

This is one of the best crime fighting tools we have seen in decades. It allows law enforcement to identify the bad guys and put them in jail. It also protects the innocent from going to jail for a crime they did not commit, added Chief Muldoon.

Dr. Jovanovich will speak along with Chief Muldoon and the Denver District Attorney, Mitch Morrissey, during a press conference today at the IACP meeting at 9:00 a.m. PT. For more information about IACP, please visit: http://www.theiacpconference.org.

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IntegenX Announces U.S. Launch of the RapidHIT™ 200 System – Rapid DNA Technology That Will Revolutionize the Use of ...

Posted in DNA

Rape DNA process 'not adequate'

1 October 2012 Last updated at 12:38 ET

Forensic procedures carried out by a private firm which wrongly linked the DNA of a man to a rape were "not adequate", a report says.

Adam Scott, from Devon, was held for a couple of months after being accused of raping a woman in Manchester.

The charges were dropped when it emerged a DNA sample had been contaminated at LGC Forensics.

Forensic Science Regulator Andrew Rennison said Mr Scott was an "innocent victim of avoidable contamination".

LGC Forensics said that it "deeply regrets the incident of contamination".

Mr Scott was charged in 23 October 2011 after a plastic tray containing a sample of his DNA was re-used in the analysis of a swab from a rape victim in Plant Hill Park, Blackley. The result of that test linked him to the crime.

The report said police investigating the rape allegations raised concerns seven weeks later because phone records suggested Mr Scott had been in Plymouth a few hours after the alleged attack.

In March this year, the government wound up the Forensic Science Service, leaving private companies and police laboratories to take on its work.

That month, news emerged of the DNA mix-up involving Adam Scott at the Teddington lab of the biggest private provider, LGC.

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Rape DNA process 'not adequate'

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Release of NASA Research Announcement NNH12ZTT001N "Research Opportunities in Space Biology"

This NASA Research Announcement (NRA) solicits hypothesis-driven research proposals for 1) Ground-Based Research Designed to Lead to Space Flight, 2) Rapid Turn-Around Space Flight Experiments 3) ISS Flight Experiments and 4) New Space Biology Investigations. NASA Space Biology experiments have one or more of the following primary goals: 1) to effectively use microgravity and the other characteristics of the space environment to enhance our understanding of basic biological processes; 2) to develop the scientific and technological foundations for a safe, productive human presence in space for extended periods and in preparation for exploration; and 3) to apply this knowledge and technology to improve our nation's competitiveness, education, and the quality of life on Earth. NASA Space Biology experiments will be designed to discover how space flight affects a diverse group of microorganisms, plants, and animals; study the effects of gravity (g) across the g-spectrum, i.e., from micro- to hyper-gravity; and characterize the biological effects of radiation, magnetic fields, and the interaction amongst species in the unusual environments of space and spacecraft.

The full text of the solicitation is available on the NASA Research Opportunities homepage at http://nspires.nasaprs.com under menu listing "Open Solicitations." Potential applicants are urged to access this site well in advance of the proposal due date to familiarize themselves with its structure and to register in the NSPIRES system. Proposals must be submitted electronically.

Step-1 proposals are due on October 31, 2012 at 5 PM Eastern Time, and invited Step-2 proposals are due on December 19, 2012 at 5 PM Eastern Time. Proposals must be submitted electronically by an authorized official of the proposing organization. Proposers can use either NSPIRES (see URL above) or Grants.gov (http://www.grants.gov) for proposal submission. NASA's selection of research projects will be guided by recommendations of the National Research Council's 2011 Decadal Survey Report, "Recapturing a Future for Space Exploration: Life and Physical Sciences Research for a New Era" (http://www.nap.edu/catalog/13048.html).

All categories of U.S. institutions are eligible to submit proposals in response to this NRA. Principal Investigators (PIs) may collaborate with investigators from universities, Federal Government laboratories, the private sector, state and local government laboratories and other countries.

Every organization that intends to submit a proposal in response to this NRA must be registered with NSPIRES, and such registration must identify the authorized organizational representative(s) who will submit the electronic proposal. Instructions on how to register in NSPIRES will be described in the NRA. Each electronic proposal system places requirements on the registration of principal investigators and other participants (e.g. co-investigators). Potential proposers and proposing organizations are urged to access the system(s) well in advance of the proposal due date(s) of interest to familiarize themselves with its structure and enter the requested information. Questions in regards to responding to this NRA may be addressed to the contacts referenced in the full solicitation document.

This is a broad agency announcement as specified in FAR 6.102 (d)(2). Notwithstanding the posting of this opportunity at FedBizOpps.gov, nspires.nasaprs.com, or Grants.gov, NASA reserves the right to determine the appropriate award instrument for each proposal selected pursuant to this announcement.

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Release of NASA Research Announcement NNH12ZTT001N "Research Opportunities in Space Biology"

Macrophage accumulation of triglycerides yields insights into atherosclerosis

Public release date: 1-Oct-2012 [ | E-mail | Share ]

Contact: Cody Mooneyhan cmooneyhan@faseb.org 301-634-7104 Federation of American Societies for Experimental Biology

Bethesda, MDA research report appearing in the Journal of Leukocyte Biology helps explain how specific immune cells, called macrophages, accumulate triglycerides to support their function. Because a characteristic finding in atherosclerosis is the accumulation of fat in macrophages in the arterial wall, understanding how macrophages accumulate triglycerides may lead to new approaches toward slowing or stopping the development of atherosclerosis.

"Activation of macrophages leads to the accumulation of triglycerides in macrophages by multiple pathways that may have beneficial effects in host defense but could contribute to the accelerated atherosclerosis that occurs in chronic infections and inflammatory disease," said Kenneth R. Feingold, M.D., a researcher involved in the work from the Metabolism Section at the Veterans Affairs Medical Center in San Francisco, California. "By understanding the pathways that lead to this lipid accumulation in activated macrophages one might be able to manipulate these pathways to stimulate lipid accumulation to improve host defense or inhibit these pathways to reduce atherosclerosis depending on the clinical circumstances."

To make this discovery, scientists conducted laboratory experiments using a macrophage cell line, or mouse peritoneal macrophages. These cells were stimulated with various substances and the effect on macrophage glucose and fat metabolism was determined. They found that activated macrophages are more efficient at taking up glucose and use this glucose to synthesize fat. They also found that activated macrophages are more efficient at taking up fatty acids and use the fatty acids to synthesize triglycerides. Finally, the breakdown of fat (triglycerides) is decreased in activated macrophages. Together these changes in macrophage metabolism lead to the accumulation of fat inside the macrophage itself. The fact that multiple pathways are altered suggests that the accumulation of fat in activated macrophages is important to the function of activated macrophages.

"Drilling down to understand exactly how triglycerides are used by our body should ultimately help us better treatments for diseases such as atherosclerosis," said John Wherry, Ph.D., Deputy Editor of the Journal of Leukocyte Biology. "This report gives us important insights into how triglycerides accumulate in key immune cells involved in atherosclerosis and cardiovascular disease."

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The Journal of Leukocyte Biology publishes peer-reviewed manuscripts on original investigations focusing on the cellular and molecular biology of leukocytes and on the origins, the developmental biology, biochemistry and functions of granulocytes, lymphocytes, mononuclear phagocytes and other cells involved in host defense and inflammation. The Journal of Leukocyte Biology is published by the Society for Leukocyte Biology.

Heather Parker, Mike Dragunow, Mark B. Hampton, Anthony J. Kettle, and Christine C. Winterbourn. Requirements for NADPH oxidase and myeloperoxidase in neutrophil extracellular trap formation differ depending on the stimulus. J Leukoc Biol October 2012, 92:841-849; doi:10.1189/jlb.1211601 ; http://www.jleukbio.org/content/92/4/829.abstract

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Macrophage accumulation of triglycerides yields insights into atherosclerosis

Fluoxetine increases aggressive behavior, affects brain development among adolescent hamsters

Public release date: 1-Oct-2012 [ | E-mail | Share ]

Contact: Lori Lennon l.lennon@neu.edu 617-680-5129 Northeastern University College of Science

BOSTON, Mass.-- Fluoxetine was the first drug approved by the FDA for major depressive disorder (MDD) in children and adolescents, and to this date, it remains one of only two selective serotonin reuptake inhibitors (SSRIs) registered for treatment of MDD in children and adolescents, despite reports that indicate this class of drugs is associated with side effects, such as agitation, hostility and aggression.

SSRIs have been amongst the most widely prescribed medications in psychiatry for over a decade. While there is a wealth of information regarding their effectiveness and safety in adults, considerably less data exists regarding whether they are safe for children.

A study published in Behavioral Neuroscience by Prof. Richard Melloni of Northeastern University shows that repeated administration of a low dose of fluoxetine to adolescent hamsters dramatically increased offensive aggression and altered the development of brain areas directly associated with controlling the aggressive response. "These data show clearly that repeated exposure to fluoxetine during adolescence directly stimulates aggressive responding and alters the normal development of two important brain systems, i.e., the serotonin and vasopressin neural systems, in a fashion consistent with the expression of the highly aggressive behavioral characteristics."

For over a decade, Prof. Melloni and his team have researched the neural and behavioral consequences of illicit drugs and prescribed medications on the adolescent brain. Importantly, the data collected during the study indicates that clinically relevant doses of fluoxetine, when administered during adolescent development, can dramatically alter the wiring of brain circuits implicated in aggression control. "These data support the notion that interactions between adolescent fluoxetine and the developing vasopressin neural system might underlie fluoxetine-induced aggressive behavior and hint that serotonin, perhaps by acting on vasopressin neurons, may play a more permissive role in this response."

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For more information on this study, please contact:

Lori Lennon Communications Coordinator/Senior Writer College of Science Northeastern University 617/373.7686 617/680.5129 (cell) l.lennon@neu.edu

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Fluoxetine increases aggressive behavior, affects brain development among adolescent hamsters

More than 200 rescued from rips at Perth beach

Treacherous surf conditions have seen hundreds of people rescued at Perth beaches as temperatures climbed into the mid 30s and thousands flocked to the sea.

Surf lifesavers were kept busy throughout with more than 200 individual rescues at Scarborough Beach alone.

In one situation, lifesavers had to launch a mass rescue as about 10 people got caught in a rip at Scarborough.

Scarborough surf life saving captain Jody Ballard says that despite the high number of rescues there have been no serious injuries.

"Just getting out to people as quick as we can and getting them back to shore safely," he said.

"No major injuries, no spinals, no near-drownings, so really a great day on the beach to start the summer with, albeit with a lot of rescues."

Surf Lifesaving says rescue jet skis were busy pulling people from the water as they got caught up and down the coast.

In an out-of-water incident, police were called after a brawl at Scarborough Beach involving a large number of people.

It is understood dozens of people started fighting on a grassy area above the beach.

Meanwhile, Surf Life Saving WA had to ground its shark patrol helicopter on the first day of its season due to mechanical issues.

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More than 200 rescued from rips at Perth beach

Snohomish County (Everett area) publishes free hiking guide of beaches to mountains

If you've got it, you may as well flaunt it.

Snohomish County, located directly north of Seattle, has outstanding hiking opportunities, from the beaches of Puget Sound to the crest of the Cascades.

The county tourism office in Everett, the county seat, wants visitors to know about its hiking gems. The Snohomish County Tourism Bureau has recently updated and published a 52-page color booklet called "Hiking in Snohomish County.''

The free guide is ideal for visitors because, for one, it's free, and also because it really does cover the best of the county. The author is Craig Romano, one of Washington's top hiking guidebook authors.

The guide can be downloaded from the county visitor website, ordered by phone (425-348-5802 ext. 10) or ordered from the website snohomish.org.

The guide describes 30 hikes in detail and includes driving directions, topographical maps and a handy chart that lists each hikes round trip distance, easy-to-difficult rating, elevation gain, best season to hike it and closest community. Also included are local resources and a list of accommodations for those who want to plan an overnight getaway around hiking.

This the third edition of "Hiking in Snohomish County," authored by Romano for the Snohomish County Tourism Bureau. Romano is an award-winning author of nine guidebooks on hiking in Washington state. He is a content provider for hikeoftheweek.com and trails editor for Outdoors NW magazine.

In this latest brochure, Romano increased the number of featured hikes from 25 to 30 and replaced some hikes in previous editions to spotlight new ones. The 30 hikes capture the full scope of hiking destinations within Snohomish County: beaches, scenic rivers, old-growth forests, alpine lakes, wildflower meadows, mountain tops, wildlife preserves, historic sites and impressive waterfalls.

For more information on Romano and his guidebooks, visit craigromano.com.

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Snohomish County (Everett area) publishes free hiking guide of beaches to mountains

Chopper found as crowd flocks to beaches

Crowds flock to the beach to escape the heat. Picture: Steve Ferrier/The West Australian

UPDATE Scraborough Beach surf life savers have been kept busy today rescuing about 130 beachgoers.

Wesfarmers Emergency Response Team had two jetskis patrolling Perth's beaches and spent about 4 hours at Scaborough Beach today where they rescued about 100 people.

At about 5.20pm today Surf Life Saving tweeted that police had been informed of a brawl at Scarborough Beach.

An estimated 20,000 flocked to beaches along Perths metropolitan coast as Swanbourne recorded 35.2C at 1.43pm.

Water conditions have been decribed as treacherous and there are a number of rips at beaches.

Club captain at Scarborough Surf Life Saving Club, Jody Ballard, reminded beachgoers not to drink and swim. He warned people that drinking and swimming can result in swimming and drowning.

The Surf Life Saving WA Westpac Lifesaver Rescue Helicopter was grounded this morning because of a mechanical fault.

SLSWA hired another helicopter to patrol metropolitan beaches this afternoon as engineers worked on the grounded chopper.

The helicopter has been patrolling over the weekend and is expected to do patrols between Yanchep and Mandurah and out to Rottnest daily, for up to four hours between 6.30am and 5pm.

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Chopper found as crowd flocks to beaches

More than 200 rescued from rips at Perth beaches

Treacherous surf conditions have seen hundreds of people rescued at Perth beaches as temperatures climbed into the mid 30s and thousands flocked to the sea.

Surf lifesavers were kept busy throughout with more than 200 individual rescues at Scarborough Beach alone.

In one situation, lifesavers had to launch a mass rescue as about 10 people got caught in a rip at Scarborough.

Scarborough surf life saving captain Jody Ballard says that despite the high number of rescues there have been no serious injuries.

"Just getting out to people as quick as we can and getting them back to shore safely," he said.

"No major injuries, no spinals, no near-drownings, so really a great day on the beach to start the summer with, albeit with a lot of rescues."

Surf Lifesaving says rescue jet skis were busy pulling people from the water as they got caught up and down the coast.

In an out-of-water incident, police were called after a brawl at Scarborough Beach involving a large number of people.

It is understood dozens of people started fighting on a grassy area above the beach.

Meanwhile, Surf Life Saving WA had to ground its shark patrol helicopter on the first day of its season due to mechanical issues.

Excerpt from:

More than 200 rescued from rips at Perth beaches

Chopper grounded as crowd flocks to beaches

Crowds flock to the beach to escape the heat. Picture: Steve Ferrier/The West Australian

UPDATE Scraborough Beach surf life savers have been kept busy today rescuing about 130 beachgoers.

Wesfarmers Emergency Response Team had two jetskis patrolling Perth's beaches and spent about 4 hours at Scaborough Beach today where they rescued about 100 people.

At about 5.20pm today Surf Life Saving tweeted that police had been informed of a brawl at Scarborough Beach.

An estimated 20,000 flocked to beaches along Perths metropolitan coast as Swanbourne recorded 35.2C at 1.43pm.

Water conditions have been decribed as treacherous and there are a number of rips at beaches.

Club captain at Scarborough Surf Life Saving Club, Jody Ballard, reminded beachgoers not to drink and swim. He warned people that drinking and swimming can result in swimming and drowning.

The Surf Life Saving WA Westpac Lifesaver Rescue Helicopter was grounded this morning because of a mechanical fault.

SLSWA hired another helicopter to patrol metropolitan beaches this afternoon as engineers worked on the grounded chopper.

The helicopter has been patrolling over the weekend and is expected to do patrols between Yanchep and Mandurah and out to Rottnest daily, for up to four hours between 6.30am and 5pm.

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Chopper grounded as crowd flocks to beaches

Astronomy Nights set

CHARLESTON The month of October will feature four consecutive weeks of Astronomy Night Exploration, starting at 7:30 p.m. Oct. 9.

The sessions include about 30 minutes inside the Charleston Carnegie Public Library in Rotary Room B, and the remaining time outdoors, in the parking lot.

The emphasis will be on naked eye and binocular observing. A 30-minute indoor discussion will be followed by outdoor observation, weather permitting.

Equipment will be discussed but none is provided. Bring your own binoculars, flash light and a blanket to lie on. This program will be open to 25 individuals or families, and a family will be counted as one registration. Registration opens Monday by phone or in person. All ages are welcome, but those under 13 must have a parent with them.

Remember to dress for the weather, as the library will be closed for the last portion of the program.

To register or for more information, call the KidSpace at 217-345-1514.

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Astronomy Nights set

Predicting erectile dysfunction from prostate cancer treatment

Public release date: 27-Sep-2012 [ | E-mail | Share ]

Contact: Michelle Kirkwood michellek@astro.org 703-286-1600 American Society for Radiation Oncology

Researchers have identified 12 DNA sequences that may help doctors determine which men will suffer from erectile dysfunction (ED) following radiation therapy for prostate cancer. Identifying these patients in advance of treatment may better inform men and their families as to which prostate cancer treatments are best for their specific cancer and lifestyle, according to a study to be published online September 27, 2012, in advance of the October 1, 2012 print issue, in the International Journal of Radiation Oncology.Biology.Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology (ASTRO). The findings could also guide doctors in recommending the most effective treatments that carry the least risk of patients developing ED.

The main treatments for prostate cancersurgery, brachytherapy (seed implants) and external beam radiation therapyare all very effective at curing prostate cancer. Unfortunately, each treatment places patients at risk for ED. Although many men will maintain their potency, doctors would like to identify which men are at greatest risk for the development of difficulty with sexual function.

In this multi-institutional, multi-national study, researchers from New York's Mount Sinai School of Medicine, Albert Einstein College of Medicine of Yeshiva University in Bronx, N.Y., New York University School of Medicine, Florida Radiation Oncology Group in Jacksonville, Fla., and Maastricht University Medical Center in Maastricht, the Netherlands, examined 593 men who were treated with brachytherapy and/or external beam radiation therapy and hormone therapy. Of them, 260 reported erectile dysfunction.

"Through a two-stage genome-wide association study, 12 single nucleotide polymorphisms (SNPs) were identified that were associated with the development of erectile dysfunction after radiation treatment for prostate cancer," said Barry S. Rosenstein, PhD, department of radiation oncology at New York's Mount Sinai Medical School. "If validated further, these SNPs could provide the basis for a blood test that would enable radiation oncologists to predict more accurately which men are most likely to develop erectile dysfunction after prostate cancer radiation therapy."

"Prostate cancer screening and treatment are undergoing major shifts," said Harry Ostrer, MD, professor of pathology and genetics at Albert Einstein College of Medicine, director of genetic and genomic testing at Montefiore Medical Center and co-principal investigator of the study. "This is part of our ongoing effort to personalize and optimize treatment for prostate cancer."

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Disclosures: One author (NS) reports to have received consulting fees or honoraria from Amgen, Ferring, Janssen, Diversified Conference Management, Prologics LLC, and Nihon MediPhysics. Another author (RS) has received fees for developing lectures and educational materials for Bard.

For complete text of the study, contact Michelle Kirkwood, 703-286-1600, press@astro.org. To learn more about the Red Journal, visit http://www.redjournal.org.

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Predicting erectile dysfunction from prostate cancer treatment

The buzz: Flying robots may get bee brains

3 hrs.

John Roach

Flying robots of the future may have the smarts of bees, a level of artificial intelligence with potential applications ranging from search and rescue missions to mechanical pollination of crops.

The first step in the Green Brain project underway at a pair of British universities is to develop accurate computer models of the neural systems that govern honey bee vision and sense of smell.

Such smarts would, eventually, allow the team to build a flying robot that can sense and act as autonomously as a bee instead of carrying out a set of pre-programmed instructions.

The $1.3 million project is led by James Marshall at the University of Sheffield in collaboration with the University of Sussex.

According to a news release, understanding the brain of the socially complex honey bee is an alternative approach to artificial intelligence research, where other teams have focused on the brains of rats, monkeys and humans.

The bee brain is smaller and more accessible than any vertebrate brain, Marshall explained.

In addition to building intelligent, autonomous robots, the research may lead to discoveries about what is causing wild honey bee populations around the world to plummet.

Or, at least, contribute to the development of mechanical pollinators such as the Robobees project at Harvard University.

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The buzz: Flying robots may get bee brains

Artificial Medical Intelligence Announces Industry’s First Robotic Computer Automated Coding for Improved ROI at …

EATONTOWN, N.J.--(BUSINESS WIRE)--

Artificial Medical Intelligence (AMI) today announced the industrys first Robotic Computer Automated solution which is fully integrated into the companys primary Natural Language Processing -Computer Assisted Coding (CAC) software, EMscribe.

Using the innovative Robotic Computer Automated Coding solution for certain outpatient records including radiology, labs as well as treat and release outpatient records, medical coders do not need to view the medical charts for coding. Instead medical records go directly to the billing department where they are automatically coded with 100% accuracy. No other Health Information Management tools have this capability. While other CAC vendors make claims of increased performance by automating certain functions within coding processes and workflow, coders are still required to verify and validate the CAC output. AMIs Robotic Computer Automated Coding requires no coder review and is always 100% accurate and complete. This means that fewer resources are needed for the overall processing of patient records within healthcare facilities.

Robotic Computer Automated Coding has a clear and direct impact for healthcare facilities coding performance and overall coding departmental processing time and expenditures. For auditing, the Robotic Computer Automated Coding output can be reviewed at any time by pulling up a specific account or medical record number through the AMI or any Graphical User Interface.

Since 2009, Butler Health System has been using EMscribe through one of AMIs partners. The hospital is currently processing more than 26,000 outpatient charts per month through the EMscribe Robotic Computer Automated Coding solution with great success. Of the charts processed, more than 60% use Robotic Coding automatically bypassing manual coding and going instead directly to the billing department. The charts that are not using the Robotic Computer Automated Coding technology are still being processed through CAC and are presented to a coder with codes suggested by the EMscribe coding engine.

This exciting Robotic Computer Automated Coding approach is completely unique from other Computer Assisted Coding offerings and helps hospitals improve the bottom line revenue cycle performance through increased speed, efficiency and elimination of coder variability, said Stuart Covit, COO, Artificial Medical Intelligence Inc. Workflow varies from site to site and that presents the potential for exaggerated productivity improvement claims made by CAC vendors. With our innovative robotic technique, there is now a fundamental differentiation and shift in the offerings available to Health Information Management. Robotic Computer Assisted Coding translates to less staff focused on the mundane task of coding certain record types. The Robotic Automation process is exclusive to AMI and has been refined and field tested in live sites for 5 years. We are now moving aggressively to provide this standout capability to all hospital sites.

EMscribe Computer Assisted Coding software utilizes AMIs innovative Natural Language Processing (NLP) coding technology to read inpatient and outpatient records for appropriate diagnostic, procedure and CPT codes. It then pre-codes the records and presents them for coder validation, verification and review. Manual coders enhanced with the results of EMscribe can easily approve or amend the automatic results and increase efficiencies by as much as 80%. EMscribe has been deployed successfully in many hospitals throughout the United States.

In addition to hospitals, healthcare technology companies looking to address ICD-I0 can benefit from EMscribe technology to interface with their existing applications. The EMscribe technology can be decoupled and bolted onto other systems that require advanced CAC/NLP for the future ICD-10 coding system. With its NLP capabilities, EMscribe can serve as a valuable solution to deal with the new, much more specific and detailed coding system.

Robotic Computer Automated Coding is available immediately. The product can be seen at the upcoming AHIMA Conference October 1-3 in Chicago through some of AMIs partners which are listed on the companys website at http://www.artificialmed.com

About AMI

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Artificial Intelligence Used to Home In on New Fossil Sites

FREIGHTER GAP, Wyo.On blisteringly hot desert sands, researchers crawled on their hands and knees avoiding fist-size cacti littering the ground.Their goal: collecting bones and teeth of some of the earliest known primates to shed light on the adaptations at the root of the evolutionary lineage that led to humans.The fossils, though, are the size of a fingernail or smaller, and they are scattered over an area of about 10,000 square kilometers in the rocky desert of Wyoming's Great Divide Basin.

That's a lot of ground to cover, especially on all fours and in searing heat. So the scientists are relying on a tool never tried before in paleontology: artificial intelligence. Such an approach might be able to pinpoint fossil troves in their giant needle-in-a-haystack quest and suggest new strategies for fossil hunting. It then remained for them to wander to the middle of the desert to see if their innovation led them on a wild goose chase or not.

Normally, discovering fossils depends largely on luck. Paleontologists can take educated guesses as to where to searchtrekking down dry stream beds to look for bones that might have eroded off slopes, for instancebut they mostly depend on walking around to see what catches the eye. If they are lucky, they can cover ground in bucking and bouncing jeeps down dirt roads set up by oil and gas companies. In any case, traditional approaches can be challenging, lengthyand fruitless.

Increasingly, paleontologists are relying on technology to narrow their search for fossils. For instance, Google Earth has helped identify sites in South Africa containing fossils of the ancient hominid Australopithecus sediba.

But instead of inspecting satellite imagery by eye for potential sites, paleontologist Robert Anemone and remote-sensing specialist Jay Emerson of Western Michigan University and their colleagues have developed a way to automate the operation using an artificial neural network, a computer system that imitates how the brain learns. Their aim was to take advantage of how brains, both natural and artificial, quickly learn and recognize patterns, such as what fossils look like.

Training the artificial brain Artificial neurons are components of computer programs that mimic real neurons in that each neuron can send, receive and process information. Researchers first train the networks by feeding data to the artificial neurons and letting them know when their computations solve a given problem, such as reading handwriting or recognizing speech. The networks then alter the patterns of connections among these neurons to change the way they communicate with one another and work together. With such practice, the networks figure out which arrangements among neurons are best at computing desired answers.

The neural network presented the promise of locating fossil-rich sites "without walking over miles and miles of barren outcrops," says paleontologist John Fleagle of Stony Brook University. "It could save lots and lots of time and expense in the field."

That's why Anemone and his colleagues were out in the Wyoming desert with a neural network running on a laptop computer. It analyzed visible- and infrared-light satellite and aerial images of the Great Divide Basin, which included 100 known fossil sites. They first let the network know that 75 of these areas were fossil-rich so it could learn what this kind of site looked like. When they had it search for the other 25 sites, it correctly spotted 20 of them, raising hopes that it could identify new candidates.

Filling gaps in the primate record The researchers were hunting fossils dating to the late Paleocene and early Eocene epochs, about 55 million to 50 million years ago, when the Rocky Mountains were first rising and the climate was significantly warmer and wetter on average than today. Back then a large freshwater lake dominated the dig region, with streams flowing to it from the surrounding mountains. The area was home to crocodiles, turtles, lizards, fish and lots of mammals, including very primitive rodents, horses and bats as well as primates similar to modern lemurs, tarsiers, lorises and galagos.

Today, the area is mostly dry sagebrush scarred and pocked with gullies, buttes and dunes. Pronghorn antelope run alongside cars and groups of elk occasionally dash in front of them. Roaming stallions greet campers in the morning with thunderous snorts, and falcons occasionally dive at the visitors to keep them away from nests. The area seems mercifully free of venomous snakes, but thunderstorms can destroy tents and clog trails with slippery mud that can trap a truck.

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Artificial Intelligence Used to Home In on New Fossil Sites

In Artificial Intelligence Competition, Two Bots Pass for Human | 80beats

In the 2012 Bot Prize competition, the true winner may be the one who makes the most mistakes. In this match, video game avatars directed by artificial intelligence compete to see which comes across as most human in a fight against real human players. This year, for the first time, human participants mistook the two bots for humans more than half the time, a feat researchers attribute to the fact that these bots were programmed to be less-than-perfect players.

During the game, the aptly namedUnreal Tournament 2004, players, of course, try to kill each other, but they also categorize each character they meet as either bot or human. As they move through their virtual world, they use whats called a judgment gun to tag the figures they encounter, and these scores, or humanness ratings, determine the winners of the competition. Since the competition started, in 2008, the goal for the programmers entering their artificial intelligences in the game has always been to achieve a robot that was mistaken for a human half the time. This time, two bots achieved it, with humanness ratings of 52 percent. Furthermore, the human players had 40 percent humanness ratings, meaning that 60 percent of the time, human players thought other human players were robots.

The key to designing a convincing bot, researchers think, is to make sure its not too perfect. An avatar directed by a human would not have perfect aim, something a computer could easily achieve, explained Jacob Schrum, a doctoral student from the University of Texas who collaborated on one of the winning bots, in a press release. Instead, a good bot would shoot worse at long distances and make illogical decisions about which characters to pursue.

Maybe now the focus will be on teaching humans to act less robotic.

Video game photo via Jacob Schrum

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In Artificial Intelligence Competition, Two Bots Pass for Human | 80beats

Eclipse Aerospace Announces Anti-Skid Brakes

Albuquerque, New Mexico, Sept. 26, 2012 (GLOBE NEWSWIRE) -- Today, Eclipse Aerospace, Inc. formally announces the addition of an Anti-Skid Braking System (ABS) as a new option for the Eclipse Twin-Engine Jet, the world's first and most efficient Very Light Jet. The new Anti-Skid Braking System is available as an option on the new production Eclipse 550 jets and will be offered as a retrofit to the existing fleet. In-aircraft testing is complete with certification and availability expected within six months.

ABS allows for maximum braking energy and skid control without the need for a conventional hydraulic system, which is unique to the Eclipse Jet. "Testing of this system has exceeded our expectations, from normal touchdown speeds to a complete stop in less than 750 feet with aggressive braking," states Cary Winter, SVP of Engineering at Eclipse Aerospace .

This innovative and proven technology will add yet another level of safety to the Eclipse Jet's robust set of safety features and stellar safety record. The new system will include two brake control valves installed in each wheel well, two axle mounted wheel speed sensors, a computer, and a software update to our Avio Processing Center software. The total installation weighs approximately seventeen pounds. Eclipse Aerospace will also be offering a weight reduction package that will minimize the weight impact of the ABS installation. The Anti-Skid Braking System will be available as an option on all IFMS equipped aircraft.

"ABS and the previously announced Auto Throttles are just two of the many exciting new features and engineering enhancements Eclipse Aerospace will be releasing in the very near future." stated Winter.

The fully certified ABS retrofit installation for the Eclipse Jet will be available in early 2013, with installation on new production Eclipse 550 Jets available at initial deliveries. Based on the performance experienced in testing, Eclipse will seek to adjust the Aircraft Flight Manual performance numbers as appropriate.

For more information and to view a video of the Eclipse Anti-Skid Brake Test, visit http://www.ECLIPSE.aero.

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Eclipse Aerospace Announces Anti-Skid Brakes

Photo Release — Retired Northrop Grumman Chief Engineer to Receive Prestigious Aerospace Vehicle Design and …

SAN DIEGO, Oct. 1, 2012 (GLOBE NEWSWIRE) -- Former Northrop Grumman Corporation (NOC) chief engineer Phil Saunders will be honored by the Society of Aerospace Engineers (SAE) International for a career of distinction in the aerospace industry. Saunders was selected for his innovations that helped fuel the company's successful development of the U.S. Air Force's B-2 stealth bomber and the U.S. Navy's X-47B Unmanned Combat Air System (UCAS).

A photo accompanying this release is available at http://media.globenewswire.com/noc/mediagallery.html?pkgid=14953

SAE plans to present its 2011 Clarence L. ("Kelly") Johnson Aerospace Vehicle Design and Development Award to Saunders during the organization's biennial AeroTech Congress and Exhibition, to be held Sept. 24-26, 2013 in Montreal.

Saunders retired in December 2011 as the chief engineer for Northrop Grumman's Navy UCAS program.

"Phil Saunders helped alter, fundamentally, the course of aviation history," said Paul Meyer, vice president and general manager for Northrop Grumman's Advanced Programs and Technology business area. "His technical innovations on B-2 and X-47B, and his disciplined, no-nonsense leadership style helped redefine the list of 'standard features' for advanced aircraft systems."

Northrop Grumman is the Navy's prime contractor for the UCAS Carrier Demonstration (UCAS-D) program, an effort that will demonstrate in 2013 the ability of a tailless, autonomous unmanned aircraft to operate safely from an aircraft carrier. The company is also the prime contractor for the B-2, the flagship of the nation's long-range strike arsenal and one of the world's most survivable aircraft.

Over the course of his career, Saunders made significant engineering contributions to several advanced air systems.

During 19 years on the B-2 program, he designed the aircraft's Lateral/Directional Control Augmentation System, a set of computer algorithms that maintains the tailless bomber's aerodynamic stability. He also managed the design, development, integration and flight test validation of the B-2's flight control and terrain following-/ terrain-avoidance systems.

Saunders later joined the Navy UCAS team, bringing with him more than three decades of experience with flying wings and tailless bodies; conformal airspeed-measuring systems; software simulations; and highly computerized guidance and flight control systems.

He used this experience to help Northrop Grumman to design, develop and produce the carrier-compatible X-47B. His expertise in stability and control systems helped his team produce an aircraft that can fly itself autonomously with high precision, and identify and respond automatically to any anomalies in its flight-critical subsystems.

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Photo Release -- Retired Northrop Grumman Chief Engineer to Receive Prestigious Aerospace Vehicle Design and ...