Watson takes glory, risks on medical school

State Sen. Kirk Watson has been the architect and the face of a campaign for a medical school and other health projects in Austin for just over a year. But the Austin Democrat worked quietly on a medical school for several years before he thrust himself into the spotlight last September at the urging of other proponents who felt he had the ability and moxie to get it done.

Now Watson has linked his goal of establishing a medical school to winning voter approval of a Travis County-wide property tax increase in November to support the endeavor.

Watson, 54, has taken on other daunting challenges in more than 20 years of off-and-on public life. He fought off testicular cancer, was mayor of Austin during a tech bust that started in 2000 and in 2002 lost a race for state attorney general.

Yet to hear him speak these days, nothing is more important and, perhaps, more career-defining than establishing a medical school at the University of Texas, as well as a new teaching hospital, comprehensive cancer-care center and other elements of what supporters call Watsons 10 in 10 10 health care goals to achieve in 10 years.

We have so many good people ready to do it that success is immensely possible, and to not do it and not get started on the path would be extraordinarily regrettable, Watson said last fall. This is big. Its going to be hard. But it needs to be done.

A watershed moment will come in November, when Travis County voters decide whether to increase their property taxes to help underwrite those goals. That question has been put on the ballot by Central Health, Travis Countys hospital district, at Watsons urging. He proposed the amount of the rate increase, a nickel per $100 of property value, before the districts board had publicly discussed any figures.

Moreover, it was Watson who helped make it possible for Central Health to hold a tax election. He authored 2007 legislation that gave the agency overseeing health care for the needy Travis County residents broader taxing, contracting and other powers than other hospital districts in the state.

Numerous civic, business and other groups have endorsed the proposed tax increase, but it has drawn criticism as well, including from some people who question Watsons ties to Central Health. For one thing, Central Health has paid Watsons law firm, Brown McCarroll LLP, $262,675 since May for legal work on the 10 in 10 plan and other matters. Four ethicists outside of Texas saw no conflict of interest but said Watson and others could have been more transparent.

Other players in the health initiatives, including officials of the University of Texas System and of the Seton Healthcare Family, say they encouraged Watson to take the lead on the medical school. Watson followed up with a speech a year ago this month at the Four Seasons Hotel unveiling his 10 in 10 plan.

Everybody was going off in different directions, said Kenneth Shine, executive vice chancellor of health affairs for the UT System. We said, We ought to create a community-based activity with people brought together from various entities. In the course of that discussion, we said, You know, the person who has the greatest credibility, the best organizational skills and great interest is Kirk Watson.

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Watson takes glory, risks on medical school

IgNobel Prize in Chemistry: Turning hair green with the power of SCIENCE

Ok, with the power of copper. But copper is all about science! So it counts.

The Ignobel prize in chemistry goes to Johan Pettersson of Sweden for determining why people in the town of Anderslv were suffering from a strange epidemic ofgreen hair. Pettersson, an engineer in environmental hygeine, dyed his own beard green for the ceremony, and was very thrilled to win the Ignobel, noting that it teaches you to look at the strange.

(Source)

The mystery began in the charming (ok, I dont know what it looks like, but I have to imagine its charming) town of Anderslov, located on the very southern tip of Sweden. People started complaining that their hair was turning green. When confronted with sudden hair changes, people are inclined to blame the drinking water, and of course, since its drinking water, you have to wonder what something in there will do to you, if its already turning your hair green.

Enter environmental hygiene engineer Pettersson. He and a team took samples of the local drinking water from several houses. They immediately suspected copper, which, well, turns things green.

(Source. Observe the older copper is green, due to exposure to water and air, while the newer copper is bright and shiny)

Imagine their surprise when they found that the copper levels in their current set of samples were totally normal. Where was the copper? The water was from the same source. Pettersson started going to the houses where people had complained, and tested THEIR water. And there was the copper, up to four times normal concentrations.

It turned out that the people who complained of the green hair were all living in new houses. New houses with shiny bright new COPPER piping. When the water sat overnight in the pipes, and was then exposed to heat from the water heater for showers in the morninghello green!

But was it harmful? Well, other than the somewhat green eggs and ham fashion, no. Copper levels high enough to dye things green are not high enough to hurt you. But, well, the green, in a country like Sweden, full of ice blondesit was a bit noticeable (Pettersson noted to me that other countries like Germany might have similarly high copper levels, but too many brunettes to notice the hair changes). It was especially noticeable in teenagers and young women, possibly because they were showering the most.

Petterssons solution? Move houses! The newer the house, the more likely you were to have copper leaching from your pipes. Of course, if you didnt want to MOVE, you could always get new pipes. If youre really desperatetake cold showers (which I think somehow would not go over well in Sweden). The heat required for hot water increases the leaching of the copper, so cold showers could help. Finally, you could, you know, do the sensible thing and let the water run for a few minutes in the morning to get the residual copper out.

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IgNobel Prize in Chemistry: Turning hair green with the power of SCIENCE

Chemistry blogging and journalism: Eat the fruit, don't count the trees

I have been blogging about chemistry and related topics since 2004. Since then I have had the chance to witness the rise of the chemistry blogosphere. What started as a small, loose collection of opinionated men and women has turned into a group of serious and well-informed bloggers who blog with authority and nuance. Partly because blogging about chemistry is not as attractive as blogging about cosmology or evolutionary biology, the chemistry blogosphere has relatively few blogs. However in my view this has also translated into an unusually high ratio of signal to noise. Speak to people who frequent this world and ask them who they think the good bloggers are, and you will usually hear lists of names that are not only similar but also exhaustive. My own contributions to this world have been very modest but there are others who have set high standards and who will undoubtedly continue to guide the high-quality discourse.

With this background in mind, I was a little disappointed to see a parting editorial by Rudy Baum who has served as editor-in-chief of Chemical and Engineering News (C&EN), the flagship publication of the American Chemical Society. C&EN has been the main source of chemical information and analysis for the chemical community for almost a hundred years. In his capacity Mr. Baum has contributed valuable input to the magazine. He has done an admirable job in keeping the whole enterprise together and has also been very active in interacting with the chemical community, including chemists who write blogs. In fact his own team of outstanding writers, scientists and journalists publish their own blog which has consistently produced insightful, high-quality content.

In his parting editorial Mr. Baum had the following words to say about blogs:

Technology has profoundly changed journalism during my tenure with C&EN. Much of the change has been positivewho can imagine doing research on a topic without access to the Internet?but the business model for journalism remains very much in a state of flux. The silly mantra, Information wants to be free, overlooks the fact that quality information requires effort, and effort costs money.

Blogs are all well and good, they add richness to the exchange of information, but they are not journalism, and they never will be.

Blogs also made an appearance in another discussion arising from a university librarys decision to cancel their subscription to ACS journals because of high prices. A post by the librarian about this was met with the following response by the ACSs Director of Public Affairs

We find little constructive dialogue can be had on blogs and other listservs where logic, balance, and common courtesy are not practiced and observed,

I would like to address the C&EN editorial first. I was not aware of the source of that silly mantra that information should be free until a few fellow bloggers pointed out that it originated with Stewart Brand, creator of the Whole Earth Catalog, the same lavish volume which inspired Steve Jobs during the early phases of his career. It was reiterated by Richard Stallman who started the open software movement at MIT. The quote is more subtle than what it appears in Mr. Baums editorial. The point is that throughout human history, for reasons related not just to cost but also to availability and censorship, information has had to tread the fine line between being withheld and being widely available. Stallman made it clear that by free he was not talking about the price but about availability. He was alluding to the fact that information by its very nature is like a restless beast that wants to spread around through the human medium. History has amply demonstrated the fact that we as a society want to know, and at some point we do. And Stallman was saying this in an age when the internet was still very limited and access to information was severely constrained compared to today.

The age has changed but information is still restricted or expensive in many cases where it should not be so. Unfortunately, simply quoting the information wants to be free gives the impression that consumers of information really think that it doesnt cost anything to produce it. Thats simply not true. Almost every person who I have talked to about open access realizes that it takes cost and effort to edit, referee and produce information. However we are also aware of how much cheaper this process can be compared to what it is, especially because of the exceedingly low costs of bandwidth and storage space. These low costs make it possible for enterprises to be supported mainly through volunteer donations. The fact is that journals and magazines as a whole are still mainly stuck in the old model where a group of editors make it their full-time job to finely craft, edit and publish information. Although the technology for disseminating information has changed, the mindsets find it hard to let go. There is of course still a prominent role for official high-quality information that is carefully vetted and journal editors still do an admirable job of striving for quality, but the fact is that there are now multiple ways of producing and accessing the same information, with blogging being one of the simplest. This proliferation of content creation and production channels has resulted in the entirely reasonable mantra that most information should be very cheap, and at least some information should be free.

The difference between free and cheap is huge; its the same as the difference between zero and any finite number. And its this mantra thatis the source of the campaign against publishers like Elsevier who practice unfair bundling and sport huge profit margins. More importantly though, I think theres at least some evidence to refute Mr. Baums statement that quality information requires effort, and effort costs money. By now Wikipedia has been proven to be a resounding example of the fact that quality can come without money through the efforts of millions of volunteers who contribute knowledge and information for a variety of reasons. Most of these contributors have contributed an immense amount of their time without asking us for a penny and the Wikipedia servers are mainly maintained through volunteer donations. Articles on Wikipedia have been vetted by experts in their respective areas (including Nature) and have been consistently found to contain high-quality information.

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Chemistry blogging and journalism: Eat the fruit, don't count the trees

New Anatomy Lab at UCSF Prepares Next Generation of Clinicians – Video

25-09-2012 23:25 The days of carrying hefty, 1500-page Gray's Anatomy textbooks may be long gone, but not much more has changed over the decades in how medical students learn anatomy - until now. Students at the University of California, San Francisco (UCSF) have just begun studies in a new, state-of-the-art anatomy learning center equipped with interactive iPad textbooks, giant video displays and roving cameras that will allow them to observe, discover, and come to understand, in a new way, the complex architecture of the human body.

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New Anatomy Lab at UCSF Prepares Next Generation of Clinicians - Video

Grey's Anatomy: Where Were We and What's Next?

Sep 26, 2012 08:28 PM ET by Natalie Abrams Follow natalieabrams Tweet

Ellen Pompeo

When Grey's Anatomy returns for its ninth season (Thursday, 9/8c on ABC), the fates of the once Stranded Six Five will be revealed.

Grey's Anatomy's Shonda Rhimes talks Season 9: Time jumps, new locations and new docs!

The last we left them, Meredith (Ellen Pompeo) and Cristina (Sandra Oh) watched their final match go out as Arizona (Jessica Capshaw), Derek (Patrick Dempsey) and Mark (Eric Dane) looked worse for wear. Did everyone survive? And did all the docs back home actually stay at Seattle Grace?

Considering executive producer Shonda Rhimes is calling this the season of romance, we can only hope we'll get some happiness this year. "I think it might be post-traumatic romance," co-star Jesse Williams says with a laugh. We'll take romance either way!

Grey's Anatomy Gallery: Where were we and what's next? Get the scoop here!

Still, the first two episodes the second of which will jump back in time to show how the docs were rescued will be quite dark. Get caught up with where we left off with the docs and get the scoop on what's next from Rhimes and the cast of the ABC medical drama in our extensive Grey's Anatomy gallery here. Suffice it to say, spoiler warning!

Grey's Anatomy returns Thursday at 9/8c on ABC.

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Grey's Anatomy: Where Were We and What's Next?

The Physiological Society and Wiley renew partnership

Public release date: 26-Sep-2012 [ | E-mail | Share ]

Contact: Ben Norman sciencenewsroom@wiley.com 44-012-437-70375 Wiley

Hoboken, NJ, September 25, 2012. John Wiley & Sons, Inc., and The Physiological Society have announced the renewal of their publishing partnership, building on over eight years of collaboration. The renewed partnership will ensure the society's titles, The Journal of Physiology and Experimental Physiology, continue to develop as thought leaders of physiological research.

"Since their establishment The Society's journals have built a reputation for excellence and quality," said Professor Jonathan Ashmore, President of The Physiological Society. "Over the last eight years this reputation has grown and our partnership with Wiley has helped to build on this."

Professor Ashmore continued, "Our journals already accommodate the needs of funders and research scientists around the world, offering an open access route for those who wish to make their article available to non-subscribers through Wiley's OnlineOpen option, and all our journal content becomes free to access after 12 months. Our renewed partnership with Wiley will ensure that the journals stay at the forefront of innovation in a time of rapid evolution in academic publishing."

"The renewal of Wiley's partnership with The Physiological Society allows us to build upon almost a decade of collaboration, with new initiatives that benefit both authors and readers of these prestigious journals," said Stephen M. Smith, President and CEO, Wiley. "Together we will continue to support and promote the latest world-class physiological research through sustained innovation using new delivery channels and models."

The Journal of Physiology publishes the latest research from across the discipline, with the aim of developing our understanding of the principles and mechanisms which govern our bodies. Published since 1879, the journal's international editorial board is led by Editor-in-Chief, Professor David Paterson of Oxford University, and currently holds an Impact Factor of 4.881.

Wiley has supported the journal's role as an opinion leader with new initiatives including the publication of dedicated neuroscience issues eight of which will be published in 2012.

Experimental Physiology, edited by Professor Paul McLoughlin of University College Dublin, focuses on emerging areas of physiological and pathophysiological research, with emphasis on molecular and cellular functions. The journal holds an impact factor of 3.211 and will move to online-only publication from 2013.

Under this renewed agreement The Physiological Society and Wiley will also collaborate closely on a number of new initiatives including Wiley's role as principal sponsor of the 2013 Union of Physiological Sciences Congress.

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The Physiological Society and Wiley renew partnership

AMP appeals breast cancer gene patent case to US Supreme Court

Public release date: 26-Sep-2012 [ | E-mail | Share ]

Contact: Mary Steele Williams mwilliams@amp.org 301-634-7921 Association for Molecular Pathology

Bethesda, MD, September 26, 2012: The Association for Molecular Pathology (AMP) has petitioned the United States Supreme Court to review the Court of Appeals for the Federal Circuit's (CAFC's) recent ruling in Association for Molecular Pathology v. U.S. Patent and Trademark Office, a case that challenges the validity of patents on two human genes, BRCA1 and BRCA2, that predispose women to hereditary breast and ovarian cancer. The American Civil Liberties Union and the Public Patent Foundation filed the appeal to the High Court on behalf of AMP and other medical and professional organizations representing over 150,000 physicians and scientists. Other plaintiffs in the suit include individual physicians and scientists, genetic counselors, women's groups and patients.

After a district court initially declared the BRCA1 and BRCA2 patents invalid in March 2010, the CAFC reversed. That decision was appealed to the Supreme Court, which remanded the case to the lower court for further consideration in light of its recent decision in Mayo v. Prometheus. In Mayo, the Supreme Court found a method patent on another biological relationship was invalid under section 101 of the Patent Act because it claimed an unpatentable natural phenomenon. Upon reconsideration, the CAFC again upheld the patents on the breast cancer genes, claiming that the patentees had invented a new chemical substance through their identification of the disease-causing genetic mutations.

"AMP is now looking to the Supreme Court to correct this wrong on behalf of patients and their at risk family members. Patents on genes such as BRCA1 and BRCA2 grant diagnostic test monopolies to commercial companies, which often assemble the genetic knowledge acquired through testing in proprietary databases to which the medical community lacks access," stated Mary Steele Williams, Executive Director of the Association for Molecular Pathology.

Iris Schrijver, MD, President of the Association for Molecular Pathology added, "Gene patents prevent pathologists from reading their patients' DNA sequences to assess their risks for disease, their prognoses, or their potential responsiveness to therapy. The result of this lack of competition is increased test costs; decreased patient access; reduced innovation in the development of new test methods; and dramatically reduced knowledge dissemination."

"The Court of Appeals' decision was disappointing," said Roger D. Klein, MD, JD, Chair of the AMP Professional Relations Committee, "but we are optimistic the High Court will continue to uphold longstanding precedents that prohibit the patenting of natural phenomena. The CAFC's majority opinion failed to acknowledge the reasoning underlying the Mayo decision. Further, it took an extremely narrow approach to the question of patent eligibility of the BRCA1 and BRCA2 genes, considering only whether there were physical changes to the genes' organizational arrangements, not whether these changes altered their fundamental properties. The essence of DNA is its ability to store the blueprints for human life within its code. The CAFC's decision was analogous", he added, "to treating genes as computer hardware, when their essence is really that of software. In this case, of course, the software code was written by nature, not man."

###

ABOUT AMP:

The Association for Molecular Pathology (AMP) is an international medical professional association dedicated to the advancement, practice, and science of clinical molecular laboratory medicine and translational research based on the applications of molecular biology, genetics, and genomics. For more information, please visit http://www.amp.org.

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AMP appeals breast cancer gene patent case to US Supreme Court

KFC Nutrition – Calories In KFC Food – Healthy Options #LLTV – Video

25-09-2012 21:27 I LOVE IT when you: Click LIKE, COMMENT, & SUBSCRIBE & SHARE these videos! ? FULL BLOG POST AT: ? MY SITE: ? GO SHOPPING ? LIVE LEAN CLOTHING: ? FOLLOW: ? INSTAGRAM: (@BradGouthro) ? LIKE: ? PINTEREST: ? FREE E-BOOK STARTER GUIDE: LIVE LEAN FOREVER: Music by: Kevin MacLeod - Cut And Dry, Kevin MacLeod (www.incompetech.com) Licensed under Creative Commons "Attribution 3.0" http

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KFC Nutrition - Calories In KFC Food - Healthy Options #LLTV - Video

Molecular process in fat cells that influences stress and longevity identified

ScienceDaily (Sep. 26, 2012) As part of their ongoing research investigating the biology of aging, the greatest risk factor for type 2 diabetes and other serious diseases, scientists at Joslin Diabetes Center have identified a new factor -- microRNA processing in fat tissue -- which plays a major role in aging and stress resistance. This finding may lead to the development of treatments that increase stress resistance and longevity and improve metabolism.

The findings appear in the Sept. 5 online edition of Cell Metabolism.

Over the past several years, it has become clear that fat cells (adipocytes) are more than just repositories to store fat. Indeed, fat cells secrete a number of substances that actively influence metabolism and systemic inflammation. Previous studies have found that reducing fat mass by caloric restriction (CR) or surgical or genetic means can promote longevity and stress resistance in species from yeast to primates. However, little is known about how CR and fat reduction produce these beneficial effects. This study investigated one type of molecular mediator -- change in microRNAs (miRNAs) and the processing enzymes required to make them- that is influenced by aging and reversed by caloric restriction. miRNAs are involved in the formation of mature RNA.

Based on studies conducted using human cells, mice and C. elegans (a microscopic worm used as a model organism for aging studies), the researchers demonstrated that levels of multiple miRNAs, decrease in fat tissue (adipose) with age in all three species. This is due to a decrease in the critical enzyme required from converted pre-miRNAs to mature miRNAs, Dicer. In the human study, which compared the miRNA levels in preadipocytes (fat cell precusors) of young, middle-aged and older people, people aged 70 and older had the lowest miRNA levels. "The fact that this change occurs in humans, mice and worms points to its significance as a general and important process," says lead author C. Ronald Kahn, MD, Chief Academic Officer at Joslin Diabetes Center and the Mary K. Iacocca Professor of Medicine at Harvard Medical School.

Caloric restriction, which has been shown to prolong lifespan and improve stress resistance in both mice and worms, prevents this decline of Dicer, and in the case of the mice, restore miRNAs to levels observed in young mice. Conversely, exposure of adipocytes to major stressors associated with aging and metabolic diseases, including toxic agents, Dicer levels decreased. Mice and worms engineered to have decreased Dicer expression in fat showed increased sensitivity to stress, a sign of premature aging. By contrast, worms engineered to "overexpress" Dicer in the intestine (the adipose tissue equivalent in worms) had greater stress resistance and lived longer.

Overall, these studies showed that regulation of miRNA processing in adipose-related tissues plays an important role in longevity and an organism's ability to respond to age-related and environmental stress. "This study points to a completely new mechanism by which fat might affect lifespan and is the first time that anyone has looked at fat and miRNAs as factors in longevity," according to co-author T. Keith Blackwell, MD, PhD, co-head of Joslin's Section on Islet Cell and Regenerative Biology and Professor of Pathology at Harvard Medical School.

Based on this study, Blackwell suggests that "finding ways to improve miRNA processing to keep miRNA levels up during aging might have a role in protecting against the stresses of everyday life and the development of age- and stress-related disease."

Dr. Kahn and the study investigators are currently working on ways to genetically control Dicer levels in the fat tissues of mice, to create mouse models that are more or less resistant to stress. "We would love to find drugs that would mimic this genetic manipulation to produce a beneficial effect," says Dr. Kahn. "If we can better understand the biology of aging, we might also understand how age impacts diabetes," says Kahn.

Study co-authors include Marcelo A. Mori, Prashant Raghavan, Jeremie Boucher, Stacey Robida-Stubbs, Yazmin Macotela, Steven J. Russell, and T. Keith Blackwell of Joslin; and James L. Kirkland and Thomas Thomou of the Mayo Clinic.

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Molecular process in fat cells that influences stress and longevity identified

Male DNA found for first time in female brains

Male DNA has for the first time been found inside the female brain, according to new research led by a Canadian scientist.

No, the finding doesn't explain why women sometimes know what their husbands are thinking.

But it could lead to refining what "the self," biologically speaking at least, really means.

Plus, in an unexpected finding, the researchers found that women with Alzheimer's disease had less male DNA in their brains -- and in lower concentrations in the brain region's most affected by the memory-robbing disease -- than women without Alzheimer's.

Observers said the finding also raises the hypothesis that, if male DNA can infiltrate a woman's brain, it might have some "masculinizing" affect on the female brain.

And, if that's so, "what consequences does this have on how the brain functions -- in other words, thinking and behaviour?" said neuroscientist Dr. Sandra Witelson, a professor in the department of psychiatry and behavioral neurosciences at the Michael G. DeGroote School of Medicine at McMaster University in Hamilton.

Appearing in the latest edition of the journal, PLOS ONE, the study is the first to describe the presence of male "microchimerism" in women's brains.

Microchimerism is the "intermingling" of small numbers of cells or portions of DNA in a person or animal from a genetically different inpidual.

In this case, the male DNA found in women's brains most likely came from cells from a pregnancy with a baby boy.

But women can acquire male DNA without ever having a son. In women without boys, male DNA can come from sharing her mother's womb with a male twin, from a non-irradiated blood transfusion and possibly even from an older sibling.

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Male DNA found for first time in female brains

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Space Debris Threat May Require Avoidance Maneuver for Space Station

Want to stay on top of all the space news? Follow @universetoday on Twitter

International Space Station officials are keeping a watchful eye on two different pieces of space junk that may require the ISS to steer away from potential impact threats. Debris from the Russian COSMOS satellite and a fragment of a rocket from India may come close enough to the space station to require a debris avoidance maneuver. If needed, the maneuver would be done using the ESAs Automated Transfer Vehicle (ATV) Edoardo Amadi. The ATV was supposed to undock last night, but a communications glitch forced engineers to call off the departure. Both pieces of debris are edging just inside the so-called red zone of miss distance to the station with a time of closest approach calculated to occur Thursday at 14:42 UTC (10:42 a.m. Eastern time.) It is not known how large the object is.

An approach of debris is considered close only when it enters an imaginary pizza box shaped region around the station, measuring 1.5 x 50 x 50 kilometers (about a mile deep by 30 miles across by 30 miles long) with the vehicle in the center.

NASA says the three-person Expedition 33 crew is in no danger and continues its work on scientific research and routine maintenance. The current crew includes NASA astronaut Sunita Williams, Japanese astronaut Akihiko Hoshide and Russian cosmonaut Yuri Malenchenko.

If the maneuver is required and NASA said it could be called off any time it would occur at 12:12 UTC (8:12 a.m. EDT) Thursday, using the engines on the ATV, which remains docked to the aft port of the Zvezda Service Module. It usually takes about 30 hours to plan for and verify the need for an avoidance maneuver.

Debris avoidance maneuvers are conducted when the probability of collision is greater than 1 in 100,000, if it will not result in significant impact to mission objectives. If it is greater than 1 in 10,000, a maneuver will be conducted unless it will result in additional risk to the crew.

Only three times during the nearly 12 years of continual human presence on the ISS has a collision threat been so great that the crew has taken shelter in the Soyuz vehicles. (Those events occured on March 12, 2009, June 28, 2011 and March 24, 2012.) During those events, the station was not impacted. While the ISS likely receives small micrometeoroid hits frequently (based on experiments left outside the ISS and visual inspections of the stations hull) no large debris impacts have occurred that have caused depressurization or other problems on the ISS.

Tuesdays initial attempt to undock the ATV was called off due to a communications error between the Zvezda modules proximity communications equipment and computers on the ATV. Russian engineers told mission managers that they fully understand the nature of the error and are prepared to proceed to a second undocking attempt, which has been postponed to Friday at the earliest, due to the potential space debris threat.

Once it is undocked, the ATV will move to a safe distance away from the station for a pair of engine firings that will send the cargo ship back into the Earths atmosphere to burn up over the Pacific Ocean.

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Space Debris Threat May Require Avoidance Maneuver for Space Station

Orbital debris sets off space station alert

Space officials are keeping a watchful eye on two different pieces of space junk that may force the International Space Station to steer away from potential impact threats.

Debris from the Russian COSMOS satellite and a fragment of a rocket from India may come close enough to the space station to require a debris avoidance maneuver. If needed, the maneuver would be done using the ESAs Automated Transfer Vehicle "Edoardo Amadi." The ATV was supposed to undock on Tuesday night, but a communications glitch forced engineers to postpone the departure.

Both pieces of debris are edging just inside the so-called "red zone" of miss distance to the station with a time of closest approach calculated to occur Thursday at 10:42 a.m. ET. It is not known how large the object is.

An approach of debris is considered close only when it enters an imaginary "pizza box" region around the station, measuring 1.5 by 50 by 50 kilometers (about a mile deep, by 30 miles across, by 30 miles long) with the vehicle in the center.

NASA says the three-person Expedition 33 crew is in no danger and continues its work on scientific research and routine maintenance. The current crew includes NASA astronaut Sunita Williams, Japanese astronaut Akihiko Hoshide and Russian cosmonaut Yuri Malenchenko.

If the maneuver is required and NASA said it could be called off any time it would occur at 8:12 a.m. ET Thursday, using the engines on the ATV, which remains docked to the aft port of the station's Zvezda service module. It usually takes about 30 hours to plan for and verify the need for an avoidance maneuver.

Debris avoidance maneuvers are conducted when the probability of collision is greater than 1 in 100,000, if the maneuver will not result in significant impact to mission objectives. If it is greater than 1 in 10,000, a maneuver will be conducted unless it results in additional risk to the crew.

If there's not enough time to conduct an avoidance maneuver, the space station's astronauts may be alerted to take shelter in their Soyuz vehicles. The last time that happened was on March 24, but the threatening object passed by without incident.

Space news from NBCNews.com

Science editor Alan Boyle's blog: A new comet superstar named C/2012 S1 (ISON) is heading for the spotlight starting in November 2013 but will it perform as some hope it will, or will it be a dud of cosmic proportions?

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Orbital debris sets off space station alert

Space station at risk of debris hit

The International Space Station is in danger of being hit by two pieces of debris from an old Russian satellite that had previously hit a US craft in 2009, a news report says.

The space station will encounter pieces of the Kosmos 2251 military spy orbiter in the next few days, the Interfax news agency quoted a source at Russian Mission Control as saying.

"Two fragments of the Kosmos 2251 craft may pose a danger to the station," the unnamed source was quoted as saying.

The source added that the station may now have to manoeuvre out of the path of the approaching debris in a special operation tentatively planned for Thursday.

The Kosmos 2251 satellite was launched by Russia in 1993 and decommissioned just two years later.

The satellite crashed into a US Iridium-33 satellite in February 2009 in the first such space accident of its kind. The collision created hundreds of smaller fragments that pose a danger to both the station and other satellites.

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Space station at risk of debris hit

New Marshall Space Flight Center Director Introduces Himself, Vision For Marshall

Posted on: 5:09 pm, September 26, 2012, by David Kumbroch, updated on: 05:49pm, September 26, 2012

REDSTONE ARSENAL, Ala. (WHNT) The Marshall Space Flight Center finds itself under new leadership again.

New Director Patrick Scheuermann faced the media and the microphones, giving him a chance to speak about himself.

Scheuermann says, I am a native of New Orleans, Louisiana. Ive been a Marshall Space Flight Center employee before as a Chief Operating Officer running the Michoud Assembly Facility.

In fact, Marshall made it through turbulent times with Scheuermanns help.

He explains, I started as a Marshall employee the Monday before Hurricane Katrina hit, and so that Monday was an interesting meeting. Tuesday, Wednesday, Thursday and Hurricane Katrina was coming, so I said let me see the emergency plan. The next two years was a blur.

But Scheuerman worked his way up in the rocket business the hard way, and now hes here at the top of Marshall Space Flight Center.

Scheuermann remembers, When I started in 1986 as a test conductor for testing space shuttle main engines, sort of like my predecessor Robert Lightfoot, he got his same start testing space shuttle engines too. For me now to go from that position to every opportunity that Ive had in the past has been just tremendous opportunity for me.

Right next to the elevators at Marshall, you find the stated goals. Even though the center has new leadership, the mission stays the same.

Scheuermann describes, The Marshall mission is strong. We look forward to having a great future here at Marshall Space Flight Center. The Space Launch System, were well on our way of design and looking forward to a first flight soon for it. Experimental flight test number one [is] coming up here in December.

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New Marshall Space Flight Center Director Introduces Himself, Vision For Marshall

NASA's Hurricane Mission A Reality Due To Cutting-Edge Technology

Image Caption: Photo of the new purple CPL with the Global Hawk. Credit: NASA

Cutting-edge NASA technology has made this years NASA Hurricane mission a reality. NASA and other scientists are currently flying a suite of state-of-the-art, autonomously operated instruments that are gathering difficult-to-obtain measurements of wind speeds, precipitation, and cloud structures in and around tropical storms.

Making these measurements possible is the platform on which the instruments are flying, said Paul Newman, the deputy principal investigator of NASAs Hurricane and Severe Storm Sentinel (HS3), managed by NASAs Goddard Space Flight Center in Greenbelt, Md. HS3 will use NASAs unmanned Global Hawks, which are capable of flying at altitudes greater than 60,000 feet with flight durations of up to 28 hours capabilities that increase the amount of data scientists can collect. Its a brand-new way to do science, Newman said.

The month-long HS3 mission, which began in early September, is actually a more robust follow-on to NASAs Genesis and Rapid Intensification Processes (GRIP) experiment that scientists executed in 2010. Often referred to as GRIP on steroids, HS3 is currently deploying one instrument-laden Global Hawk from the NASA Wallops Flight Facility on Virginias Eastern Shore to look at the environment of tropical storms. In 2013 and 2014, a second Global Hawk will be added that will focus on getting detailed measurements of the inner core of hurricanes.

Without this new aircraft, developed originally for the U.S. Air Force to gather intelligence and surveillance data, the team says the mission wouldnt be possible.

The Global Hawks ability to fly for a much longer period of time than manned aircraft will allow it to obtain previously difficult-to-get data. Scientists hope to use that data to gain new insights into how tropical storms form, and more importantly, how they intensify into major Atlantic hurricanes information that forecasters need to make better storm predictions, save lives, and ultimately prevent costly coastal evacuations if a storm doesnt warrant them.

Because you can get to Africa from Wallops, well be able to study developing systems way out into the Atlantic, Newman explained. Normal planes, which can fly for no more than about 10 hours, often miss the points where storms intensify, added Gerry Heymsfield, a Goddard scientist who used NASA Research and Development funding to create one of the missions six instruments, the High-altitude Imaging Wind and Rain Airborne Profiler (HIWRAP). With the Global Hawks, we have a much higher chance of capturing these events. Furthermore, we can sit on targets for a long time.

Just as important as the aircraft are the new or enhanced instruments designed to gather critical wind, temperature, humidity, and aerosol measurements in the environment surrounding the storm and the rain and wind patterns occurring inside their inner cores, they added. The instruments bring it all together, Newman said. We didnt have these instruments 10 years ago.

The Global Hawk currently on deployment at Wallops is known as the environmental aircraft because it samples the environment in which hurricanes are embedded. It carries three instruments.

A Goddard-provided laser system called the Cloud Physics Lidar (CPL) is located in the nose. CPL measures cloud structures and aerosols, such as dust, sea salt particles, and smoke particles, by bouncing laser light off these elements. An infrared instrument called the Scanning High-resolution Interferometer Sounder (S-HIS), provided by the University of Wisconsin in Madison, sits in the belly of the aircraft. It measures the vertical profile of temperature and water vapor.

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NASA's Hurricane Mission A Reality Due To Cutting-Edge Technology

NASA's new goal: Returning samples from Mars

(SPACE.com) The next steps in NASA's Mars exploration strategy should build toward returning Martian rocks and dirt to Earth to search for signs of past life, a new report by the space agency's Red Planet planning group finds.

The report, released today (Sept. 25) by the Mars Program Planning Group (MPPG), lays out a series of options that NASA could employ to get pieces of the Red Planet in scientists' hands here on Earth. The space agency is now mulling those options and could announce its chosen path by early next year, when the White House releases its proposed budget for fiscal year 2014.

"The first public release of what plans, you know, we definitively have would not be until the president presents that budget to Congress in February of 2013," John Grunsfeld, associate administrator for NASA's Science Mission Directorate, told reporters today.

NASA put together the MPPG this past March to help restructure its Mars strategy in the wake of cuts to the space agency's robotic exploration program.

The MPPG was instructed to consider NASA's newly constrained fiscal situation and the priorities laid out by the U.S. National Research Council's Planetary Science Decadal Survey, which was released last year. President Barack Obama's directive that the agency get astronauts to the vicinity of Mars by the mid-2030s was another factor, NASA officials said.

The MPPG's focus on sample-return should thus come as no surprise. It was a top priority of the Decadal Survey, and sample-return could help spur and work in concert with NASA's plans for human exploration of Mars, Grunsfeld said. [7 Biggest Mysteries of Mars]

"Sample-return represents the best opportunity to find symmetry technologically between the programs," he said. "Sending a mission to go to Mars and return a sample looks a lot like sending a crew to Mars and returning them safely."

Humans could even be involved in the sample-return process, according to the MPPG report. Astronauts aboard NASA's Orion capsule, which is currently under development, could intercept the Martian sample in deep space, secure it in a contained environment, and bring it safely down to Earth.

"It is taking advantage of the human architecture, because we anticipate it will be there," Grunsfeld said. "And it potentially solves an issue of, when we return samples, somewhere we have to make sure that the samples are completely contained so there's no chance -- remote as it may be -- that there is something on Mars that could contaminate Earth."

Exactly when a Martian sample could come down to Earth remains up in the air. But NASA is considering launching the first enabling mission along this path in 2018, or perhaps 2020, Grunsfeld said. A complicating factor is that NASA has just $800 million or so to work with for the project through 2018.

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NASA's new goal: Returning samples from Mars

Nanotechnology device aims to prevent malaria deaths through rapid diagnosis

ScienceDaily (Sep. 24, 2012) A pioneering mobile device using cutting-edge nanotechnology to rapidly detect malaria infection and drug resistance could revolutionise how the disease is diagnosed and treated.

Around 800,000 people die from malaria each year after being bitten by mosquitoes infected with malaria parasites. Signs that the parasite is developing resistance to the most powerful anti-malarial drugs in south-east Asia and sub-Saharan Africa mean scientists are working to prevent the drugs becoming ineffective.

The 5.2million (4million) Nanomal project -- launched September 26-- is planning to provide an affordable hand-held diagnostic device to swiftly detect malaria infection and parasites' drug resistance. It will allow healthcare workers in remote rural areas to deliver effective drug treatments to counter resistance more quickly, potentially saving lives.

The device -- the size and shape of a mobile phone -- will use a range of latest proven nanotechnologies to rapidly analyse the parasite DNA from a blood sample. It will then provide a malaria diagnosis and comprehensive screening for drug susceptibility in less than 20 minutes, while the patient waits. With immediately available information about the species of parasite and its potential for drug resistance, a course of treatment personally tailored to counter resistance can be given.

Currently for malaria diagnosis, blood samples are sent to a central referral laboratory for drug resistance analysis, requiring time as well as specialised and expensive tests by skilled scientists. Additionally, confirmation of malaria is often not available where patients present with fever. Very often, drug treatments are prescribed before the diagnosis and drug resistance are confirmed, and may not be effective. Being able to treat effectively and immediately will prevent severe illness and save lives.

The Nanomal consortium is being led by St George's, University of London, which is working with UK handheld diagnostics and DNA sequencing specialist QuantuMDx Group and teams at the University of Tuebingen in Germany and the Karolinska Institute in Sweden. It was set up in response to increasing signs that the malaria parasite is mutating to resist the most powerful class of anti-malaria drugs, artemisinins. The European Commission has awarded 4million (3.1million) to the project.

Nanomal lead Professor Sanjeev Krishna, from St George's, said: "Recent research suggests there's a real danger that artemisinins could eventually become obsolete, in the same way as other anti-malarials. New drug treatments take many years to develop, so the quickest and cheapest alternative is to optimise the use of current drugs. The huge advances in technology are now giving us a tremendous opportunity to do that and to avoid people falling seriously ill or dying unnecessarily."

QuantuMDx's CEO Elaine Warburton said: "Placing a full malaria screen with drug resistance status in the palm of a health professional's hand will allow instant prescribing of the most effective anti-malaria medication for that patient. Nanomal's rapid, low-cost test will further support the global health challenge to eradicate malaria."

The handheld device will take a finger prick of blood, extract the malarial DNA and then detect and sequence the specific mutations linked to drug resistance, using a nanowire biosensor. The chip electrically detects the DNA sequences and converts them directly into binary code, the universal language of computers. The binary code can then be readily analysed and even shared, via wireless or mobile networks, with scientists for real-time monitoring of disease patterns.

The device should provide the same quality of result as a referral laboratory, at a fraction of the time and cost. Each device could cost about the price of a smart phone initially, but may be issued for free in developing countries. A single-test cartridge will be around 13 (10) initially, but the aim is to reduce this cost to ensure affordability in resource-limited settings.

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Nanotechnology device aims to prevent malaria deaths through rapid diagnosis

Penn Medicine Receives $7.7 Million Grant from Department of Defense to Help Determine Most Effective Strategies for …

PHILADELPHIA Researchers from the Perelman School of Medicine at the University of Pennsylvania (www.med.upenn.edu) have been awarded a $3.7 million grant from the National Institutes of Health (NIH) to establish a new translational interdisciplinary research center to explore the role of sex and gender in behavioral health.

The new Center for the Study of Sex and Gender in Behavioral Health will be led by C. Neill Epperson, MD, associate professor of Psychiatry and founder and director of the Penn Center for Women's Behavioral Wellness, as principal investigator, along with Tracy L. Bale, PhD, Center co-director and associate professor of Psychiatry at the Perelman School of Medicine and director, Neuroscience Center at the University of Pennsylvania School Of Veterinary Medicine.

It is well established that sex and gender are critical determinants of mental health and mental illness. But what isnt clear is how hormonal developmental milestones such as puberty and early life traumatic events interact to impact neuropsychiatric health in women across the lifespan, said Dr. Epperson. Using behavioral and molecular models of stress and reproductive neuroendocrinology, psychophysiology, and neuroimaging, the new Center for the Study of Sex and Gender in Behavioral Health will investigate the unique mechanisms at play in womens behavioral health.

Studies have found that gender differences occur particularly in the rates of common mental disorders - depression, anxiety and somatic complaints. These disorders, in which women predominate, affect approximately 1 in 3 people in the community and constitute a serious public health problem.

This new Center provides a powerful mechanism by which we can translate results from an animal model examining early life stress directly to human studies, bench to bedside and back again, said Dr. Bale. Our frequent interactions as a research team mean that we can discuss our results as they are obtained, immediately implementing important new directions and outcomes.

The new Centers research projects will focus on how the experience of early childhood adversity in womens lives reprograms the brain toward stress dysregulation, and how this intersects with periods of dynamic hormonal flux across the life span, including pregnancy and aging. While the Centers present studies will focus primarily in the translational neuroscience of the sex bias for affective disturbances in females, Drs. Epperson and Bale will promote the inclusion of sex and gender as factors in research across all Schools, Centers and Institutes at the University of Pennsylvania.

The Perelman School of Medicine is currently ranked #2 in U.S. News & World Report's survey of research-oriented medical schools. The School is consistently among the nation's top recipients of funding from the National Institutes of Health, with $479.3 million awarded in the 2011 fiscal year.

The University of Pennsylvania Health System's patient care facilities include: The Hospital of the University of Pennsylvania -- recognized as one of the nation's top "Honor Roll" hospitals by U.S. News & World Report; Penn Presbyterian Medical Center; and Pennsylvania Hospital the nation's first hospital, founded in 1751. Penn Medicine also includes additional patient care facilities and services throughout the Philadelphia region.

Penn Medicine is committed to improving lives and health through a variety of community-based programs and activities. In fiscal year 2011, Penn Medicine provided $854 million to benefit our community.

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Penn Medicine Receives $7.7 Million Grant from Department of Defense to Help Determine Most Effective Strategies for ...