GHC’s Dr. Ed Group joins Natural News Talk Hour

(NaturalNews) This week's NaturalNews Talk Hour features Dr. Edward Group, D.C., ND discussing "The Green Body Cleanse , Organic Detoxification at its Best". Discover how to reduce and eliminate toxins from your home, workplace and especially your body. It runs this Thursday evening at 6pm Pacific / 9pm Eastern, and registration is FREE. Simply enter your email address in the registration form on the right column of this page and you'll receive call-in details for the broadcast. http://www.dreddyclinic.com/products/ghchealth.htm

The NaturalNews Talk Hour is a "behind the scenes", up close and personal look at the most important issues of our time. Discover what the mainstream media hasn't told you about the secrets of optimal health, freedom and the pursuit of happiness.

Jonathan Landsman, host of NaturalNews Talk Hour, says "Dr. Group offers the kind of information that makes it easy for us to enjoy a more rewarding, happy and healthy life. His knowledge, love and compassion are true gifts to us all. I'm honored to be able to share his talents with our listening audience." Read more...

Improve your memory

GHC's Dr. Ed Group joins Natural News Talk Hour

(NaturalNews) This week's NaturalNews Talk Hour features Dr. Edward Group, D.C., ND discussing "The Green Body Cleanse , Organic Detoxification at its Best". Discover how to reduce and eliminate toxins from your home, workplace and especially your body. It runs this Thursday evening at 6pm Pacific / 9pm Eastern, and registration is FREE. Simply enter your email address in the registration form on the right column of this page and you'll receive call-in details for the broadcast. http://www.dreddyclinic.com/products/ghchealth.htm

The NaturalNews Talk Hour is a "behind the scenes", up close and personal look at the most important issues of our time. Discover what the mainstream media hasn't told you about the secrets of optimal health, freedom and the pursuit of happiness.

Jonathan Landsman, host of NaturalNews Talk Hour, says "Dr. Group offers the kind of information that makes it easy for us to enjoy a more rewarding, happy and healthy life. His knowledge, love and compassion are true gifts to us all. I'm honored to be able to share his talents with our listening audience." Read more...

Improve your memory

2 Genes Linked to Embryonic Brain Impairment in Down’s Syndrome

Down's syndrome (DS) is an incurable, heritable disorder affecting an estimated 400,000 people in the U.S. It is characterized by impaired cognitive ability and abnormal physical growth. Whereas scientists have long known that DS is caused by inheriting an extra copy of all or part of chromosome 21 , the underlying cause of the brain defects common in Down's patients has not been fully gleaned.

Now, a collaborative team of scientists working with a mouse model of DS has discovered that just two genes are responsible for the majority of the brain abnormalities present in their animals. The scientists hope that their findings will help scientists understand brain defects in humans with the disorder as well as aid in the development of drugs to treat the cognitive impairment in Down's patients.

[More]

Add to digg
Add to StumbleUpon
Add to Reddit
Add to Facebook
Add to del.icio.us
Email this Article




Genetic disorder - Health - Conditions and Diseases - Gene - Brain

2 Genes Linked to Embryonic Brain Impairment in Down's Syndrome

Down's syndrome (DS) is an incurable, heritable disorder affecting an estimated 400,000 people in the U.S. It is characterized by impaired cognitive ability and abnormal physical growth. Whereas scientists have long known that DS is caused by inheriting an extra copy of all or part of chromosome 21 , the underlying cause of the brain defects common in Down's patients has not been fully gleaned.

Now, a collaborative team of scientists working with a mouse model of DS has discovered that just two genes are responsible for the majority of the brain abnormalities present in their animals. The scientists hope that their findings will help scientists understand brain defects in humans with the disorder as well as aid in the development of drugs to treat the cognitive impairment in Down's patients.

[More]

Add to digg
Add to StumbleUpon
Add to Reddit
Add to Facebook
Add to del.icio.us
Email this Article




Genetic disorder - Health - Conditions and Diseases - Gene - Brain

Increasing Diet Polyunsaturated Fat in Place of Saturated Fat Reduces Risk of Coronary Heart Disease

Reduced saturated fat (SFA) consumption is recommended to decrease coronary heart disease (CHD), but there is an absence of strong supporting evidence from randomized controlled trials (RCTs) of clinical CHD events and few guidelines focus on any specific replacement nutrient. Additionally, some public health groups recommend lowering or limiting polyunsaturated fat (PUFA) consumption, a major potential replacement for SFA.

The overall pooled risk reduction was 19% (RR = 0.81), corresponding to 10% reduced CHD risk (RR = 0.90) for each 5% energy of increased PUFA.

These findings provide evidence that consuming PUFA in place of SFA reduces CHD events in RCTs. This suggests that rather than trying to lower PUFA consumption, a shift toward greater population PUFA consumption in place of SFA would significantly reduce rates of CHD.

References:
Image source: Varieties of meat, Wikipedia, public domain.

Posted at Clinical Cases and Images. Stay updated and subscribe, follow us on Twitter and connect on Facebook.


Resveratrol Thesis on Reaction Attempts

A few days ago Andrew Lang suggested to Dustin Sprouse that he submit his thesis to the Reaction Attempts database. Like many undergraduates Dustin put in a lot of time and effort in doing experiments and writing up his results but didn't have quite enough time to obtain all that would have been required for a traditional publication.

A thesis is an unusual document within the context of scientific communication. Unlike a peer reviewed paper, it may contain a large number of "failed experiments" and a substantial amount of speculation. Although it is not quite as detailed as lab notebook, there is often plenty of raw data and details about how failed or ambiguous experiments proceeded.
In Dustin's case we felt that there was enough information provided to include his thesis in Reaction Attempts. In addition, his thesis was accepted by Nature Precedings, thus providing a convenient means of citation.
The first component of the Reaction Attempts project is to quickly abstract the most basic information from synthetic organic chemistry reactions. This includes the ChemSpiderIDs and SMILES from the reactants and target products and brief notes about conditions and outcomes. We are especially interested in failed or ambiguous experiments because these have almost no chance of being communicated and indexed in the traditional systems. When attempting to carry out a reaction, it can be just as useful to know what doesn't work - and more specifically how it doesn't work.
The second component of the project is dissemination. Because the information is encoded semantically, it can be automatically converted to both human and machine readable formats.
One human interface consists of a PDF book (also as a hard copy), with the option of selected reactions specified by listing CSIDs of reactants in the URL. For example Dustin's reactions can be presented selectively here. We also have a Reaction Explorer, where reactants or products can be selected from a dropdown menu or via a substructure search.
We also provide live XML feeds so that others can create applications easily from machine readable data. For example one could create reaction chains automatically, which will occur whenever we enter reactions from multi-step syntheses like Dustin's - based on the synthesis of resveratrol.
I know that Peter Murray-Rust has been very active in automatically abstracting information from chemistry theses. It would be interesting to see how that approach would work for this thesis, especially with the failed experiments. Reducing a page or two of text into only the most salient bits of information manually required a level of judgement that I imagine would be tricky to do automatically.

Tonight! Morbid Anatomy in Conversation with Stephen Asma, Author of "On Monsters: An Unnatural History of Our Worst Fears," Bryant Park Reading Room

Tonight at Bryant Park Reading Room! Stephen Asma and I talk monsters, within and without, as investigated in his recent book On Monsters: An Unnatural History of Our Worst Fears. Full details follow; Hope to see you there!!

Word for Word Université at Bryant Park
In cooperation with Oxford University Press

Presents

Stephen Asma, author of On Monsters: An Unnatural History of Our Worst Fears

In conversation with

Joanna Ebenstein, Morbid Anatomy Blog and Library

“Real or imagined, literal or metaphorical, monsters have exerted a dread fascination on the human mind for many centuries. Using philosophical treatises, theological tracts, newspapers, films, and novels, author Stephen T. Asma unpacks traditional monster stories for the clues they offer about the inner logic of our fears and fascinations throughout the ages.” – Amazon.com review

Please join us for a fascinating discussion of the monsters in our lives and our need to classify them. Stephen Asma is the distinguished scholar and Professor of Philosophy at Columbia College Chicago. Joanna Ebenstein is the creator and writer of the Morbid Anatomy blog and the related Brooklyn-based Morbid Anatomy Library.

Place: Bryant Park Reading Room*
Date: July 21, 2010
Time: 7pm

This program is free to the public. For more details, visit http://www.bryantpark.org.

*The Bryant Park Reading Room is located on the 42nd Street side of Bryant Park, between 5th Avenue and Sixth Avenue. Look for the big burgundy/white umbrellas.

Directions to Bryant Park: Subways B, D, F, V to 6th Ave. @ 42nd St. 7 line to 5th Ave.@ 42nd St.; Bus M1, M2, M3, M4, Q32, to 5th Ave.@ 42nd St.; M5, M6, M7 to 6th Ave.@ 42nd St.

More information about the event and the venue can be found here. You can find more about Stephen Asma's books here and here and more about he and his work here.

Image: As used in Asma's book, and as seen in the Anatomical Theatre exhibition: Museum of Anatomical Waxes “Luigi Cattezneo” (Museo Delle Cere Anatomiche “Luigi Cattaneo”): Bologna, Italy "Iniope–conjoined twins" Wax anatomical model; Cesare Bettini, Early 19th Century

GHC’s Dr. Ed Group joins Natural News Talk Hour

(NaturalNews) This week's NaturalNews Talk Hour features Dr. Edward Group, D.C., ND discussing "The Green Body Cleanse , Organic Detoxification at its Best". Discover how to reduce and eliminate toxins from your home, workplace and especially your body. It runs this Thursday evening at 6pm Pacific / 9pm Eastern, and registration is FREE. Simply enter your email address in the registration form on the right column of this page and you'll receive call-in details for the broadcast. http://www.dreddyclinic.com/products/ghchealth.htm

The NaturalNews Talk Hour is a "behind the scenes", up close and personal look at the most important issues of our time. Discover what the mainstream media hasn't told you about the secrets of optimal health, freedom and the pursuit of happiness.

Jonathan Landsman, host of NaturalNews Talk Hour, says "Dr. Group offers the kind of information that makes it easy for us to enjoy a more rewarding, happy and healthy life. His knowledge, love and compassion are true gifts to us all. I'm honored to be able to share his talents with our listening audience." Read more...

Improve your memory

Cassini Sees Building Snowballs

The shepherding moon Prometheus creating waves and building snowballs in the Saturn F - ring. Click for larger. Image Credit: NASA/JPL/SSI

Check out this latest Cassini release. It’s a really cool picture of Saturn’s F-ring showing the wake channels made as the little moon Prometheus moves around it.

The picture is a bit hard to interpet, so  here is a page with movie choices that will help show what is going on, sorry, not great for dial up users, but the description will help along with the main press release below.  Now we know why the ring rarely looks the same every time we see it.

Here’s the Cassini press release to better describe what’s going on:

While orbiting Saturn for the last six years, NASA’s Cassini spacecraft has kept a close eye on the collisions and disturbances in the gas giant’s rings. They provide the only nearby natural laboratory for scientists to see the processes that must have occurred in our early solar system, as planets and moons coalesced out of disks of debris.

New images from Cassini show icy particles in Saturn’s F ring clumping into giant snowballs as the moon Prometheus makes multiple swings by the ring. The gravitational pull of the moon sloshes ring material around, creating wake channels that trigger the formation of objects as large as 20 kilometers (12 miles) in diameter.

“Scientists have never seen objects actually form before,” said Carl Murray, a Cassini imaging team member based at Queen Mary, University of London. “We now have direct evidence of that process and the rowdy dance between the moons and bits of space debris.”

Murray discussed the findings today (July 20, 2010) at the Committee on Space Research meeting in Bremen, Germany, and they are published online by the journal Astrophysical Journal Letters on July 14, 2010. A new animation based on imaging data shows how one of the moons interacts with the F ring and creates dense, sticky areas of ring material.

Saturn’s thin, kinky F ring was discovered by NASA’s Pioneer 11 spacecraft in 1979. Prometheus and Pandora, the small “shepherding” moons on either side of the F ring, were discovered a year later by NASA’s Voyager 1. In the years since, the F ring has rarely looked the same twice, and scientists have been watching the impish behavior of the two shepherding moons for clues.

Prometheus, the larger and closer to Saturn of the two moons, appears to be the primary source of the disturbances. At its longest, the potato-shaped moon is 148 kilometers (92 miles) across. It cruises around Saturn at a speed slightly greater than the speed of the much smaller F ring particles, but in an orbit that is just offset. As a result of its faster motion, Prometheus laps the F ring particles and stirs up particles in the same segment once in about every 68 days.

“Some of these objects will get ripped apart the next time Prometheus whips around,” Murray said. “But some escape. Every time they survive an encounter, they can grow and become more and more stable.”

Cassini scientists using the ultraviolet imaging spectrograph previously detected thickened blobs near the F ring by noting when starlight was partially blocked. These objects may be related to the clumps seen by Murray and colleagues.

The newly-found F ring objects appear dense enough to have what scientists call “self-gravity.” That means they can attract more particles to themselves and snowball in size as ring particles bounce around in Prometheus’s wake, Murray said. The objects could be about as dense as Prometheus, though only about one-fourteenth as dense as Earth.

What gives the F ring snowballs a particularly good chance of survival is their special location in the Saturn system. The F ring resides at a balancing point between the tidal force of Saturn trying to break objects apart and self-gravity pulling objects together. One current theory suggests that the F ring may be only a million years old, but gets replenished every few million years by moonlets drifting outward from the main rings. However, the giant snowballs that form and break up probably have lifetimes of only a few months.

The new findings could also help explain the origin of a mysterious object about 5 to 10 kilometers (3 to 6 miles) in diameter that Cassini scientists spotted in 2004 and have provisionally dubbed S/2004 S 6. This object occasionally bumps into the F ring and produces jets of debris.

“The new analysis fills in some blanks in our solar system’s history, giving us clues about how it transformed from floating bits of dust to dense bodies,” said Linda Spilker, Cassini project scientist at NASA’s Jet Propulsion Laboratory in Pasadena, Calif. “The F ring peels back some of the mystery and continues to surprise us.”

The late Kevin Beurle was made the honorary first author on this paper because of his contributions in developing software and designing observation sequences for this research. He died in 2009.

The Cassini-Huygens mission is a cooperative project of NASA, the European Space Agency and the Italian Space Agency. JPL, a division of the California Institute of Technology in Pasadena, manages the mission for NASA’s Science Mission Directorate, Washington, D.C. The Cassini orbiter and its two onboard cameras were designed, developed and assembled at JPL. The imaging operations center is based at the Space Science Institute in Boulder, Colo.

Here comes Katla? | Cosmic Variance

Being kind of a volcano/earthquake geek, I regularly check in on the recent California earthquake records, the Kilauea activity, and, in the past couple months since the Eyjafjallajokull, the earthquake activity near it that might presage an eruption of Eyja’s big sister, Katla. Historically, eruptions of Eyjafjallajokull are followed by eruptions of Katla, which are an order of magnitude larger. The eruption of Eyjafjallajokull disrupted air travel in Europe for weeks. It’s interesting to consider what a big volcano Katla might do. There is also the fact that Katla erupts every 40-80 years and hasn’t erupted since 1918, making this a potentially bigger buildup to an eruption. Some of the Katla eruptions in the past have gone on for months.

Since I have been watching, the number of earthquakes near Katla has been small, with a few periods of a dozen or so within a 24 hour period. Almost every time I have looked it’s been very quiet, perhaps one or two a day. I was away the previous two weeks, and apparently missed a day with 11 earthquakes on July 10. I checked again today, and I got the map below, with over a dozen earthquakes! Now, clearly, these are all small earthquakes, with magnitude near 1, and there are no reports of steam or ash as yet.

I bet it’s coming, though, fairly soon. The president of Iceland does, too.

Katla


The olm: the blind cave salamander that lives to 100 | Not Exactly Rocket Science

The browser you are currently using does not support the Discover photo galleries. Supported browsers include recent versions of Mozilla Firefox, Microsoft Internet Explorer (version 7 or later), Google Chrome, and Apple Safari.

If you have any questions or feedback, please email webmaster@discovermagazine.com. Thank you for reading Discover, and we apologize for the inconvenience.

This sketch of the olm appeared in an Austrian text published in 1768 by Josephus Nicolaus Laurenti, who game the animal its scientific name. <br />

In the caves of Slovenia and Croatia lives an animal that’s a cross between Peter Pan and Gollum. It’s the olm, a blind, cave-dwelling salamander, also called the proteus and the “human fish”, for its pale, pinkish skin. It has spent so long adapting to life in caves that it’s mostly blind, hunting instead with various supersenses including the ability to sense electricity. It never grows up, retaining the red, feathery gills of its larval form even when it becomes sexually mature at sweet sixteen. It stays this way for the rest of its remarkably long life, and it can live past 100.

The olm was once described as a baby dragon on account of its small, snake-like body. It’s fully aquatic, swimming with a serpentine wriggle, while foraging for insects, snails and crabs. It can’t see its prey for as it grows up, its eyes stop developing and are eventually covered by layers of skin. It’s essentially blind although its hidden eyes and even parts of its skin can still detect the presence of light. It also has an array of supersenses, including heightened smell and hearing and possibly even the ability to sense electric and magnetic fields.

The caves of Slovenia and Croatia have provided the olm with safe haven for over 20 million years, but these unchanging habitats are changing quickly. Chemical pollutants leaching into the caves and the attentions of eager black market collectors have seriously hit the olm population, and it is now vulnerable to extinction. Scientists have risen to the challenge by setting up various “cave laboratories” throughout Europe to save and study this iconic species at the same time.

One such laboratory lies in Moulis, France. In 1952, a group of scientists set up several riverbed-like basins in a local cave to mimic the olm’s natural habitat. The animals are protected and regularly fed. Sixty years on, there are more than 400 individuals in the cave, making it the only successful olm breeding programme in the world. And ever since 1958, researchers have been recording births and deaths among the olms on a weekly basis. Thanks to their painstaking census, we now have a unique glimpse into this odd creature and how it lives as long as it does.

Yann Voituron from the University of Lyon has analysed the five decades of data and found that the oldest olms are around 48-58 years old. Still, they show no sign of age-related physical decline. Based on the adults’ survival rates, Voituron calculated that the species lives to an average age of 69 years, supporting reports of captive olms living to 70.

Across different animal groups, the average lifespan can be anywhere from 10-67% of the maximum one. This means that at the very least, the oldest olms should be able to hit a respectable age of around 102 years and it may well live for even longer. Perhaps Voituron’s grandchildren will be able to check up on the same olms that he’s now studying.

Among back-boned animals, the bigger you are, the longer you live (generally speaking – there are exceptions). Whales, elephants and giant tortoises all top the longevity record books, but the humble olm can reach a century while weighing in at a puny 20 grams. The only other amphibian to even approach its lifespan is the giant salamander, which is a thousand times heavier. You can see how unusual the olm is in the graph below in the gallery above, which plots the lifespan of living amphibians against their mass. The olm is the black dot, looming over the clustered throng of white ones.

The deeper mystery here is how the olm achieves such a long life. The standard explanation says that ageing is the result of the very chemical reactions that power our lives. These reactions furnish us with energy but produce highly reactive molecules called free radicals, which damage any DNA or protein that they touch. Over the years, this constant barrage takes a toll on our bodies and ageing is the result; longer lives can therefore be achieved by stopping the onslaught of free radicals, so the story goes.

There are two main ways of doing this, but neither applies to the olm. Reducing your metabolism could do the trick. Since free radicals are the by-products of energy-producing chemical reactions, species that opt for life in the slow lane will produce less of them. As a group, salamanders are hardly go-getters, but the olm’s metabolic rate isn’t any lower than that of its much shorter-lived cousins. An alternative is to cope with the steady flow of free radicals with antioxidants that neutralise them. But again, the olm’s antioxidant abilities aren’t anything to shout about.

Something else must be happening in this bizarre creature and for now, it’s a mystery that goes unsolved. Voituron thinks that this tiny salamander will open some promising doors into the biology of ageing for years to come.

It might have something to do with the predator-free nature of the olm’s caves. Species that can escape from an early death often live longer than their peers, including birds and bats that can take to the air, and tree-dwelling mammals that can hide among the branches. Perhaps the safety of the olm’s home has allowed it to evolve an extreme lifespan without sacrificing its metabolism. Indeed, Darwin himself commented on the safety of the olm’s caves in his famous tome On the Origin of the Species:

Far from feeling surprise that some of the cave-animals should be very anomalous…as is the case with blind Proteus… I am only surprised that more wrecks of ancient life have not been preserved, owing to the less severe competition to which the scanty inhabitants of these dark abodes will have been exposed.”

Reference: Biology Letters http://dx.doi.org/10.1098/rsbl.2010.0539

More on ageing:

If the citation link isn’t working, read why here


Twitter.jpg Facebook.jpg Feed.jpg Book.jpg

NCBI ROFL: First-person shooter games as a way of connecting to people: “brothers in blood”. | Discoblog

Dag 3 - Storkamp by Pål Berge“This work seeks to understand young adults’ motives for online gaming and extends previous research concerning social interaction in virtual contexts. The focus of the study is on Counter-Strike and World of Warcraft. Drawing on Baudrillard’s concept of simulacra, an analysis of young gamers’ motivation for gaming is carried out. The empirical data was generated employing a mix of qualitative methods such as researcher introspection, observation, and interviews with young adults in two different online gaming centers in Stockholm during 2006 and 2007. The results show that online gaming is foremost motivated by social reasons providing the gamers with a possibility of cooperation and communication. Some of the gamers in the study were motivated by escapism. Online gaming also provides gamers with an experience in which “flow” can be obtained and serves as a “hallucination of the real,” making it possible to do things and try out behaviors that would be impossible to do or try in real life. The gamers felt that online gaming gave them more experiences than real life could provide. For research purposes, this work provides a better understanding of the motivational aspects for gamers.”

shooters_blood_brothers

Photo: flickr/Pål Berge

Related content:
Discoblog: NCBI ROFL: The ideal elf: identity exploration in World of Warcraft.
Discoblog: NCBI ROFL: Gaming at work positively correlated with multitasking.
Discoblog: NCBI ROFL: Are National Guardsmen the positive or negative control?

WTF is NCBI ROFL? Read our FAQ!


Knowledge is not value-free | Gene Expression

This isn’t The New Yorker, and I’m not writing twenty page essays which flesh out all the nooks and crannies of my thought. When I posted “Linguistic diversity = poverty” I did mean to provoke, make people challenge their presuppositions, and think about what they’re saying when they say something.

I think knowledge of many languages is awesome. I am weak at language acquisition myself, but, as someone with an interest in Bronze Age Near Eastern history I’m obviously invested in people having some comprehension of Sumerian and Akkadian (not to mention Hittite or ancient Egyptian). And I’m not someone who has no interest in the details of ethnographic diversity. On the contrary I’m fascinated by ethnic diversity. Like many people I enjoy reading monographs and articles on obscure groups such as Yazidis (well before our national interest in Iraq) and the Saivite Chams of Vietnam. Oh, wait, I misspoke. I actually don’t know many people who have my level of interest in obscure peoples and tribes and the breadth of human diversity. If you’re the type of person who reads monographs on Yazidis not because it pertains to your scholarly specialty, but because you’re interested in a wide range of facts and topics, and would like to have discussions with someone of similar disposition (me), contact me with your location and if I swing through town we can have coffee or something. I’m interested in meeting like minds who I can explore topics with (and here I’m not talking about someone who is a Hakka and so knows a lot about the history of the Hakka; I’m not Hakka and I know something about the Hakka and I’m not an Oirat I know something about the Oirat, and so forth). All things equal the preservation of linguistic diversity is all for the good, and not only does it enrich the lives of humanity as a whole, it enriches my life in particular because of my intellectual proclivities. But all things are not equal.


Destruction_of_Buddhas_March_21_2001First, let me digress and admit that I do not adhere to a plain utilitarianism which does not value the cultural accretions and symbolic residues of history. For a concrete example, consider the destruction of the Buddhas of Bamyan in 2001 by the Taliban. On a concrete material level this was simply the rearrangement of molecular aggregations. We even have the visual sensory representation of the Buddhas before their destruction in the form of photographs. Why the outrage? Naturally Buddhists were outraged because the images of the Buddha had a sacred valence for them. But the world in general was outraged, Buddhist and non-Buddhist. The local Shia Muslims who live in the region, the Hazaras, were aghast at the cultural destruction, as they considered the Buddhas to be part of their heritage. At the time the Hazaras were being subjected to genocidal persecution from the Taliban, who considered them racially alien due to their Mongolian heritage and also heretics because of their Shia faith, so they were in no position to interpose themselves between the Taliban and the Buddhas.

As for the Taliban their concept of the Buddhas of Bamyan is that they were plain stone. Additionally, the Taliban perceived that the Buddhas were blasphemous because they were idolatry, drawing upon a long line of iconoclasm which goes back to the legendary Abraham. Unlike the atheist the Taliban may have perceived in the stone something more than material, rather, the stone may have been an expression of demonic or devilish forces in the world. Even if it lacked malevolent spirit forces, if they were objects of worship by human beings then that naturally violated their conception of the proper order of things.

But there’s a more nuanced context to the destruction of the Buddhas: Afghanistan was suffering through a famine during that period. Though the proximate cause for their destruction seems to have been the influence of the Arabs who were a power in Afghanistan at the time, Arabs who had no cultural affinity for Afghanistan’s pre-Islamic heritage, I have read that one aggravating issue may have been that the leadership of the Taliban was offended that the world seemed more focused on the potential destruction of statues than on the suffering of flesh & blood people. You can extrapolate this sort of objection pretty easily; at the same time that the Buddhas of Bamyan were under threat, tens of thousands were dying weekly in the Congo.

Here is where I must admit that my actions suggest that I am no simple utilitarian, who prioritizes the suffering of flesh and blood above stone and symbol. At the time in 2001 I specifically remember being very concerned about the destruction of the Buddhas, though I did not imbue them with spiritual value. I do not imbue the pyramids of Giza with spiritual value in a deep metaphysical sense, but I would be concerned about their destruction. I am not the only one. How many Egyptians would have to die in local violence to obtain the same world-wide media coverage as a terrorist detonation of a series of devices which destroyed the pyramids? I estimate on the order of millions (and even here, I am not so sure, as the genocide of millions in Africa receives far less coverage than I believe that a destruction of the pyramids would entail).

250px-The_Earth_seen_from_Apollo_17Human life and suffering are balanced against the aesthetic of life itself, which is more than bread and water. How many millions could have been fed with the funds which went to the Apollo mission? And yet what dollar value could we put on the photo of the pale blue dot? What dollar value on the reality that a human being has stepped foot on another planet? These are difficult questions in some ways because assessments of value and worth need to get the root of one’s implicit calculations. I know many people from the biological sciences who have little use for space exploration. And yet I know many people of marginal academic inclination who perceive much of biological research to be esoteric and without direct utility.

And it is here that biologists can respond that the domain of knowledge leads directly to discoveries in medicine and technology which will enable greater human happiness and well being, no matter what one thinks of the millionth beetle cataloged. On the margin some of these justifications for research based on plausible utility are as ludicrous as the justifications for a manned space mission. But the attempt must be made. Whether the quest for knowledge is worthy or not is not evaluated by some objective abstract criteria; even if researchers sit on granting committees the funds must ultimately come from elsewhere.

Which brings me back to the extinction of languages. The Lousy Linguist is skeptical of my contention that very high linguistic diversity is not conducive to economic growth or social amity. I outlined the theoretical reasons previously. If you have a casual knowledge of history or geography you know that languages are fault-lines around which intergroup conflict emerges. But more concretely I’ll dig into the literature or do a statistical analysis. I’ll have to correct for the fact that Africa and South Asia are among the most linguistically diverse regions in the world, and they kind of really suck on Human Development Indices. And I do have to add that the arrow of causality here is complex; not only do I believe linguistic homogeneity fosters integration and economies of scale, but I believe political and economic development foster linguistic homogeneity. So it might be what economists might term a “virtuous circle.”

A more on point response came from John Hawks:

I’m sympathetic to recognizing the real loss that accompanies the disappearance of a language from the world of speakers. The “unique oral history” and “lost in translation” ideas are true as far as they go — the value of folk art and oral history is that they enable social relationships.

But most communities of a few hundred speakers don’t have a Beowulf. Unique perspectives and unique history, to be sure — just as every Rembrandt is unique. But every Rembrandt is not the Night Watch. Most unique perspectives are about the speaker’s life. At some point we can’t learn the stories of all our ancestors anyway, because there are simply too many of them. Obviously I think we should enable people to learn about their history, yet we can’t keep communities pinned like butterflies in a cabinet of curiosities.

Human language communities in prehistory had a few hundred to a few thousand speakers. Those communities shared the same basic social lives and needs. Ninety-five percent or more of all those languages were lost — and those remaining have mostly come from a handful of languages less than 10,000 years ago.

I read in the Rijksmuseum that art historians figure more than 95% of the work of artists from the Dutch golden age had been lost or destroyed over the last 300 years.

John says it with more sensitivity and sympathy for the issue than I did, but I agree 99% with what he is saying here. The only point I might quibble over is that perhaps all groups do have their Beowulf. And yet it doesn’t matter. If the speakers of the language decided to shift to another language, then they are making the choice which increases their own flourishing. Speakers of a few hundred languages are not always in the circumstances of Native or Aboriginal peoples in North America, where they can gain sympathetic hearing for preservation of their folkways from the government and majority population. They need to make the best decision for themselves at the time, and often assimilation is the best of all choices, because the sample space of choices is limited. It is correct that bilingualism, or resistance to linguistic assimilation can persist. Hasidic Jews in New York City have communities where English is a second language and adults, of the third generation born and raised in the United States, have strong accents. But this community’s insulation comes at a cost, their relative poverty.

450px-IPad-02But for most communities the level of poverty of Hasidic Jews, or the material deprivation of the Amish, is wealth indeed. Many groups in Africa, South Asia and Australasia have not moved far up on Maslow’s hierarchy of needs. Many of these groups live in grotesque poverty, experience radical marginalization, and some of them fear for their individual survival, not just tribal or ethnic coherency. If those in the developed world do value the preservation of these groups and the richness which they add to the world by their very existence, then a concrete program has to be offered. Perhaps a massive direct wealth transfer to targeted ethnic groups which are being assimilated (in India and Southeast Asia conversion to Christianity has been the most efficacious manner in which to preserve ethnic and linguistic identity, so perhaps one should donate to evangelical missionary groups). Or, the selective sponsored immigration of whole tribes and ethnic groups to the West, with an agreement that these groups have a sort of spatial sovereignty similar to Native Americans. In this way they wouldn’t be subject to the same dynamics as they were in their nation of origination.

I don’t care about linguistic diversity enough to support either of these programs. But that’s an expression of my values. And, I think it’s an expression of the values of most humans (granted, most humans do not value knowledge, but they do pay taxes which fund social engineering projects so their opinion counts). For those who do value linguistic diversity, to be taken seriously you need to present more than what it offers you and your own interests when you bear none of the costs of marginalization. Aggregate intangible utility may be maximized by this diversity, but it is simply unjust for that aggregate utility to be gained at the expense of the ones adding the diversity at the cost of their exclusion from the nation-states in which they’ve found themselves.

Addendum: Spencer Wells has noted that there is somewhat the same issue with genotypic diversity, as small groups are absorbed into larger groups. By analogy, one might offer up a program whereby tribal members are encouraged to marry only their own ingroup so as to preserve genetic lineages which may be of intellectual interest, and add diversity to the world. This is naturally the sort of argument many racialists present, though with a slightly different spin.

Image Credits: Wikimedia, CNN, Glenn Fleishman

China’s Latest Environmental Ills: Oil Spills and Copper Mines | 80beats

dalian-portTwo Chinese bodies of water made pollution headlines this week: the Yellow Sea is home to an oil spill, and the Ting River to waste water from a copper processing plant.

The Ting River

The waste water came from the Zijinshan mine in China’s Fujian province. Though earlier this month mine operators blamed weather for waste water entering the river, this week they admitted to and contaminating the river with–as The Sydney Morning Herald puts it–”four Olympic-size swimming pools” worth of waste water containing acidic copper.

Zijin’s board of directors expresses “its deep regret regarding the incident and the improper handling of information disclosure by the company, for causing substantial losses to the fish farmers located at the reservoir downstream of the mine and having a harmful impact on society,” the company said yesterday. [Bloomberg Businessweek]

Chinese police have detained two of the mine’s operators. Meanwhile, acidic copper has reportedly killed 4 million pounds of fish and threatens drinking water.

Reports from China’s official Xinhua News Agency suggest that Zijin is being required only to fix the problem and compensate locals with an offer of three yuan for every kilogram of dead fish. That makes the potential payout about 6 million yuan, [about $900,000]. [Sidney Morning Herald]

The Yellow Sea

Two oil pipelines have exploded in the port city of Dalian and have covered what the AP reports to be around 70 square miles of ocean. That’s not much compared to the 2,700 square miles covered by the Gulf of Mexico spill, but the spill is still a relatively big one in China’s recent history and certainly dramatic given its fiery start.

Images of 100-foot-high (30-meter-high) flames shooting up near part of China’s strategic oil reserves drew the immediate attention of President Hu Jintao and other top leaders. Now the challenge is cleaning up the greasy brown plume floating off the shores of Dalian, once named China’s most livable city. [AP]

Chinese reporters say that the no more oil is entering the sea and that officials have deployed 800 fishing boats to join 24 ships already on scene to stop the oil’s spread before it reaches international waters.

Economic activity in the north-eastern port has been seriously disrupted. Six “very large crude carriers”, with about 12m barrels of oil, were expected to be diverted, possibly to South Korea or other terminals in China with the capacity for such large vessels. Ships carrying imported corn have also been forced to dock elsewhere. Thousands of firefighters have doused the flames and port engineers have staunched the leak, but the clean-up mission will take at least four more days, according to the domestic media. [The Guardian]

Related content:
80beats: Isn’t It Ironic: Green Tech Relies on Dirty Mining in China
80beats: 1/3 of China’s Yellow River Not Even Fit for Industrial Use
DISCOVER: China’s Syndrome—will China be able to curb it’s pollution problem?
DISCOVER: China Promises Pollution Cleanup

Image: Wikimedia / Dalian / ASDFGHJ


ScienceBlogs has good blogs | Gene Expression

I don’t have real value to add on the ScienceBlogs controversy. The only thing I want to mention is that there are some nascent superstar weblogs on that network which aren’t big names, yet, but perhaps will be. You can miss them coming in via the front page because they don’t crank out 10-15 posts per day, but they make them count when they do post. Two new weblogs which have caught my attention are Thoughtful Animals and Observations of a Nerd. There are others too if you poke around (your disciplinary focus may differ).

At this point I think for some people ScienceBlogs is not a the optimal venue. Obviously I was one of those people, as I left in late March. But for other people the reach of a prominent network still has utility. No need to throw the baby out with the bathwater. So by all means, let’s keep track of the SB Diaspora, but there are also diamonds in the rough who aren’t budging.

Underappreciated Star-Shaped Brain Cells May Help Us Breathe | 80beats

AstrocytreAstrocytes, it was long believed, were little more than the scaffolding of the brain—they provided a support structure for the stars of the show, the neurons. But a study out in this week’s Science is the latest to suggest that this is far from the whole story. The study says that astrocytes (whose “astro” name come from their star-shape) may in fact play a critical role in the process of breathing.

Astrocytes are a type of glial cell — the most common type of brain cell, and far more abundant than neurons. “Historically, glial cells were only thought to ‘glue’ the brain together, providing neuronal structure and nutritional support but not more,” explains physiologist Alexander Gourine of University College London, one of the authors of the study. “This old dogma is now changing dramatically; a few recent studies have shown that astrocytes can actually help neurons to process information” [Nature].

Gourine’s team peeked into the brains of rats to figure out the connection between astrocytes and breathing. In humans and in rodents, the level of carbon dioxide in the blood rises after physical activity. The brain has to adjust to this, setting the lungs breathing harder to expel that CO2.

Astrocytes, the scientists found, are key players in this process. When the cells sensed a decrease in blood pH (because the carbon dioxide made it more acidic), they immediately released calcium ions, which the researchers could detect because they’d given the rats a gene encoding a protein that shone fluorescent in the presence of calcium. The astrocytes also released the chemical messenger ATP. That ATP appeared to trigger the nearby neurons responsible for respiration, kicking them into gear.

The astrocytes are no one-trick ponies, though. They could be important not only for breathing, but also for brain circulation, memory formation, and other activities.

The next step is to find a way to inhibit astrocytes in vivo, said Gourine. Then, researchers will be able to test the numerous hypotheses for the functions of astrocytes in the brain. It is likely astrocytes in various regions of the brain serve different functions, said [Cendra] Agulhon, just as many different types of neurons do many different jobs. “Depending on where they are and what kind of neurons they are surrounded by, they will function differently,” she added. “We are just starting to understand how important astrocytes can be” [The Scientist].

Related Content:
DISCOVER: The Brain, all of our mentally stimulating columns
DISCOVER: The Dark Matter of the Brain
The Loom: The Dark Matter of the Brain, Continued
80beats: Star-Shaped Brain Cells May Provide Actual Food for Thought

Image: Wikimedia Commons


Friendly Atheist interview | Bad Astronomy

While I was at TAM 8, Hemant Mehta and Robin Ferguson from The Friendly Atheist and interviewed me about the JREF, my Sooper Sekrit Project, and many things skeptical. It was too long to transcribe, so they put it up as a recording.

If you’re wondering about my razor joke right at the very start, I was poking fun at their recording device, which looks much like my shaver. But we covered a lot of ground, including PepsiGate, Skeptologists, and of course my talk at TAM 8 which has caused, to my bemusement, so much controversy. I’ll have more about that later, but for now you’ll hear something about it in this interview.


Hope for the Needle-Phobic: A Painless Vaccine “Patch” | 80beats

shotReplacing a traditional needle with a fingernail-sized patch may one day make some immunizations painless and possibly more effective. A study published in Nature earlier this week shows that a patch–a square of “microneedles” that are too short to register a typical shot’s sting and that dissolve in the skin–effectively immunized mice against a strain of the flu virus.

The researchers have yet to test the patch on humans, and that next step could take a few years; the move from a successful animal trial to a human trial isn’t a small feat. Still, many see this patch’s promise. As Paul Offit, director of the Vaccine Education Center and chief of infectious diseases at Children’s Hospital of Philadelphia, says:

“The caveat is, this needs to be extended to humans…. It’s not uncommon for vaccines or vaccine delivery systems to look very promising in experimental animals, then fail in humans. But there is every reason to believe this kind of technology could be applicable to children and adults.” [HealthDay News]

If the patch proves successful in human studies, here are some reasons it might quickly catch on.

Less Packaging

Traditional flu immunization shots deliver vaccines via metal, hypodermic needles. The leftover? A contaminated needle that goes straight to the biohazard bin. Researchers have designed this patch’s microneedles to disappear after application. They are made from a “bicompatible polymer” that holds the vaccine directly. After immunization, the needles dissolve into the skin itself as they deliver the vaccine, leaving only a watersoluble backing. Explains study coauthor Richard Compans:

“With respect to [the previous] vaccine delivery, we worked with solid metal needles…. The current technology is different because the vaccine is contained in the needle itself, and there is no needle left after the process.” [Tech News Daily]

Less Pain

As their name implies, microneedles are short–shorter than .03 inches each. That’s too short to trigger the pain associated with a traditional shot. The patch has a grid of 100 of the tiny needles as opposed to one large metal one.

Each microneedle is 650 microns long, about as tall as 10 human hairs stacked on top of each other…. They are arrayed in a grid-like pattern on a patch that’s easy to stick on your arm. [Los Angeles Times]

More Protection

There may be other benefits from a shot not going as deep. The study tested three groups of mice: one given no flu vaccine, one given a flu vaccine in the traditional way, and one given the vaccine via the microneedle patch.

Infecting the mice with the flu virus thirty days after immunization, both the mice vaccinated traditionally and with the patch successfully fought off the virus. To test how long the vaccine worked, the researchers then vaccinated a different three sets of mice. Three months later, the mice vaccinated with the patch actually performed better than the needle-immunized mice–more easily clearing the virus from their lungs.

Researchers suspect that the reason may be skin cells’ different immune reaction to virus attackers, which they encounter more often than muscle cells do (where traditional flu shots deliver the vaccine).

Skin, it seems, may trigger the immune system better than muscle, according to Richard Compans, professor of microbiology and immunology at Emory University School of Medicine: “The skin is a particularly attractive site for immunization because it contains an abundance of the types of cells that are important in generating immune responses to vaccines.” [CNET]

Less Postage?

Although traditional delivery systems for standard vaccines are working in many places, the researchers think that a patch vaccine might allow a more rapid and effective response to unexpected outbreaks. Instead of asking people at risk to go to a central location like a flu clinic, doctors could mail them a do-it-yourself patch.

[Coauthor Mark R.] Prausnitz says it’d be much easier if people could either vaccinate themselves or have someone less skilled vaccinate them instead of requiring a doctor or nurse. If the patches are one day approved by the FDA, Prausnitz envisions people ordering patches through the mail or at their local pharmacies.”The technology is ready to take the next step into humans,” says Prausnitz. “Our main barrier is getting funding.” [NPR]

Related content:
80beats: Ice-Loving Bacteria Could Give Humans a Vaccine Assist
80beats: New HIV Hope? Researchers Find Natural Antibodies That Thwart the Virus
80beats: Vaccinating School Kids Can Protect the Whole “Herd” of Community Members
80beats: This Week in Swine Flu: Vaccines Arrive, and Doctors Combat Myths

Image: flickr / El Alvi


What You See When a Kingfisher’s About to Eat You | Visual Science

A female kingfisher plunges into a pond in southwestern England hot on the tail of a tasty little fish. These birds’ eyes have special filters thought to reduce glare, giving them a clearer view of underwater prey from above. A third eyelid, called a nictitating membrane, protects their eyes when they strike the water at high speed.

Photographer Charlie Hamilton James placed the camera in a waterproof box and set it up in the pond, wired to an infrared trigger that fired when something crossed its path. This image was the result of several weeks of patient monitoring. James: “When shooting wildlife my aim is to show the subjects as they exist in their environment. This is particularly the case with kingfishers, which are more often than not shot close up with wide-angle lenses in order to show them in their river landscape.”

Charlie Hamilton James/Nature Picture Library