Solar Powered Floating Home

the-last-resort-by-rafaa-51Floating homes have long been a dream for both designers and island owners who want to maintain the ecological purity of their island without compromising on luxury.

One of the most recent designs that is in the early development stages is both luxurious and eco-friendly. This solar powered floating home is about 5 meters wide and 15 meters long with two levels. Sleeping bunks, mechanical equipment and hatches are on the lower level and the upper level contains living space, a kitchen, a bathroom and two bedrooms. In total there are six beds and a sliding panel helps close off the rooms for more privacy. Vertical blinds on the facade act as a shading device for the interior as well as a privacy system. Stairs lead up to the roof, which serves as an extra deck, and roof integrated solar panels generate electricity for the two electric engines that propel the home.

Source: inhabitat.

Will Pathology PACS eliminate injuries or cause different ones?

I wonder who is more susceptible to work-related injuries.  Pathologists or radiologists?  Is anyone aware of any data as that below for radiology for pathology?  Will pathology PACS eliminate stress and strain from microscope use or simply create other injuries?

Radiologists may be prone to work-related injuries

By Erik L. Ridley
AuntMinnie staff writer

Thanks to a lack of attention paid to developing comfortable and ergonomic work spaces, radiologists appear susceptible to work-related musculoskeletal symptoms, according to research presented Monday at the American Roentgen Ray Society (ARRS) meeting in San Diego.


Researchers from Massachusetts General Hospital (MGH) in Boston found that only 7.2% of surveyed radiologists did not have any work-related musculoskeletal symptoms. Investments in training and education seem required to address this health risk to radiologists, according to the study team.

"It's an important problem that affects every radiologist, regardless of your level of training, what specialty you're in, your location, and [whether you're in] academic or private practice," said Dr. Anand Prabhakar, a clinical fellow in abdominal imaging. "We need to do something about it before it becomes very debilitating to people."

Following anecdotal reports that many radiologists suffer from work-related musculoskeletal symptoms, the MGH research team sought to determine the prevalence of these symptoms in radiologists at a large tertiary-care hospital. They also wanted to investigate the effects of several workstation ergonomic factors and work habits on these symptoms, according to Prabhakar.

They administered a written questionnaire to 28 randomly selected radiologists (17 male, 11 female; age range = 36-50 years) from various divisions of a single radiology department. All of these radiologists primarily utilized PACS and speech recognition for interpretation, but also occasionally viewed hard-copy images, according to the researchers.

The questionnaire gathered information such as demographics, work-related musculoskeletal symptoms, work habits, and workstation design. Of the respondents, 50% had worked on the same system for longer than five years. In addition, 96% had two to three monitors at their workstation.

Only 7.2% were symptom-free, and 70% had seen a physician for work-related musculoskeletal symptoms. The researchers also found that 75% had changed their work schedule in response to symptoms.

Prevalence of musculoskeletal symptoms included:

  • Neck pain in 42.8%
  • Lower back pain in 39.2%
  • Headache in 32.1%
  • Shoulder pain in 32.1%
  • Wrist pain in 7.4%

The MGH researchers also discovered that three radiologists (17%) never adjusted their chairs; all had three or more symptoms of musculoskeletal pain. Only 32.3% of respondents always adjust their chairs, while 42.8% said they sometimes did.

As for adjusting their monitors, 60.7% never did. Elbow rests were never used by 53.5% of respondents, of which 46% had shoulder pain. Only 50% had a regular exercise program.

However, the researchers did not find any relationship between those who had more adaptive responses overall and those who had fewer symptoms.

Prabhakar attributed the prevalence of musculoskeletal problems to a combination of factors, including the piecemeal approach of putting together radiology work spaces in the PACS era.

"For example, the PACS station is not purchased at the same time [from] the same vendor; it's not integrated with, say, the desk, telephone, mouse, keyboard, and dictation system," he told AuntMinnie.com. "There really has not been any interest in somebody putting it all together and really taking into account radiologist comfort."

Cost also can be a factor, Prabhakar said. Training and education are often not provided on how to set up work spaces to be more comfortable and ergonomic.

In another notable survey finding, radiologists expressed strong preferences for having more tools for combating repetitive stress injury, some of which are very low cost, he said. For example, approximately 70% of respondents thought a wireless mouse would be helpful and approximately 60% said a wireless keyboard would be helpful. And although it would be more expensive than a wireless keyboard or wireless mouse, more than 80% of respondents wanted a desk with an adjustable height.

"If we can somehow test whether those small things could help people, then I think it's a small investment in the long-term health of radiologists," he said. "I suspect, and I haven't proven it, that if radiologists are more comfortable, then they're going to work more efficiently. And that will increase productivity, which I think is the measure that administrators will look at before they invest in it."

As for specific steps radiologists can take to improve their work-space environment, Prabhakar suggests examining recommendations produced by the U.S. Department of Labor's Occupational Safety and Health Administration (OSHA). Those guidelines, which are available online as an e-tool, provide a range of tips for creating safe and comfortable workstations.

"Ultimately, I hope that this project inspires other people to take control of their own workspace, maybe inspire industry or academic institutions to address the problem, and hopefully future research will prove that this may improve our productivity," he said.

Future research efforts will evaluate the impact of training and education on the symptoms of work-related musculoskeletal symptoms, Prabhakar said.

Why NASA? [Part II of II]

In my last entry, I made what I believe is the fundamental case for space exploration – the fact that the survival of our species ultimately depends on it.  Perhaps the world’s most reknowned cosmologist, Stephen Hawking shares this view and, with the help of computer graphics, illustrated it on the Discovery Channel with tonight’s episode of “Into the Universe” – The Story of Everything.

Not only do we have external and internal threats to our continued existence, we have a final time limit of about one billion years.  The Sun is in its “middle age,” but it will eventually expand – in about five billion years – into what is called a red giant star.  At this point, it will have stopped fusing hydrogen in its core and will only be burning in the outer shells.

These regions where fusion is still taking place will expand out from the core and, eventually, engulf the Earth itself.  Long before its physical destruction, though, the planet will be rendered uninhabitable by the increased radiation as the Sun continues to age.  Even before the transition to a red giant, the Sun’s output will be so strong in a billion years that the oceans will boil off and the hydrogen lost to space.

Red Giant Sun
Video of the Sun expanding in its red giant phase

There are no “ifs, ands, or buts” about it.  We will not be able to call Earth our home forever.  By that time, we must have learned how to live on other worlds and, eventually, even how to cross the vast distances between the stars.  Though we may be able to live on Mars or terraformed moons of the outer planets for a time, the Sun’s expansion is likely to eject Mars and the outer planets into deep space.

Even if we figure out a way to stay in the solar system on entirely artificial habitats, the Sun will eventually die.  The outer layers will be cast off into a nebula of gas and dust.  Fusion will cease completely.  All that will remain is an extremely dense white dwarf, cooling away until it no longer even emits heat.

Yes, a billion years is a very long time from now.  The fact that we can even conceptualize such a problem, though, is a credit to our species.  We will have to solve it, eventually.  With today’s space programs, we are taking the first steps.  Russian rocket pioneer Konstantin Tsiolkovsky said that Earth is the cradle of humanity, but that we cannot stay in the cradle forever.

blog post photo
Artist’s concept of a lunar base (NASA)

So, what role should the government have in all this?  Why should we even have a NASA?

First, I look to the Constitution itself.  At the very beginning, the Preamble says that our government was created, in part, to “provide for the common defence” and to “secure the Blessings of Liberty to ourselves and our Posterity.”

Given the potential near-term threats from space hazards to life, liberty, and property and the long-term necessity of space travel for our continued survival, I’d say we’re pretty well covered there.  A just government exists to protect the rights of its citizens through reasonable measures and in accordance with the rule of law.  Thus, a just government has an inherent interest in protecting its citizens against space-based threats and developing the means to do so.

The Constitution grants Congress the power to pay for such a capability and the President the authority to direct both the armed forces and any other agency established by Congress to execute that capability.  Some also argue that the Constitution grants Congress the ability to promote science and “the useful Arts,” but I think that is an overly generous interpretation of the clause granting Congress power to establish patents and copyrights.

If we agree that the US government has a just role in protecting its citizens and American property (including assets in space) from threats beyond our atmosphere, you still might ask why we don’t just let the military handle it all.  Until the Space Act of 1958, that’s precisely what the case was.

President Eisenhower and Congress agreed that the United States should have separate, but parallel, military and civilian space programs, unlike the centralized military system in the Soviet Union.  NASA was created to coordinate all non-military activity in space, as the commercial and civilian benefits of space applications were recognized early on.  This had the added benefit of initiating multiple development paths for American rocketry in its race with the Soviet Union for space supremacy.

Sputnik
Sputnik – The first artificial satellite and the beginning of the Space Race

However, we won the Space Race.  We beat the Soviets to the Moon.  Since then, our government has largely taken the position that what NASA does best is inspire the nation through its pursuit of science in space.  We’ve spent the past forty years trying to either figure out “what’s next?” or get back to where Apollo left off.

While basic science research is more important than ever, especially with the closing of private research institutions like the venerable Bell Labs, and is a vital component of ensuring NASA has the knowledge it needs, I don’t think that is necessarily the best attitude to have about NASA as an agency.  I think NASA has an obligation to be directly relevant to the country’s vital interests, beyond nebulous claims of our importance to prestige and technology research.

The Space Act itself says that “the general welfare and security” of our country require that NASA seek and encourage the “fullest” commercial use of space.  It also requires NASA have a watch program for Near-Earth Objects to “provide warning and mitigation of the potential hazard,” I might add.

Space exploration for its own sake is enough to get me out of bed in the morning, go for my run, shower, and head down to Clear Lake.  However, it has become clear to me that isn’t enough to justify the cost to the American taxpayer, as much as many of my colleagues wish the politicians would just give us the money and leave us alone.

In the process of carrying out its Congressionally-designated mission to protect the Earth from space-based threats and increase our understanding of the planet and space phenomena, NASA can and must undertake initiatives that help solve America’s strategic problems.  By thoughtful selection of NASA’s programs, we can all get the best of both worlds.

For example, rare-earth metals are resources both vital to modern technology and largely supplied by foreign countries, like China.  There is serious concern that China may restrict the supply of these materials to feed their own domestic needs.  Preliminary surveys of some Near-Earth Objects suggest that they might have more usable metals, including rare-earth elements, than has ever been mined in the history of civilization.

NASA technology developed to study, track, and deflect threatening asteroids could possibly be commercialized to provide the United States with vital commodities that we lack in abundance within our borders, if it can be done economically and safely.

blog post photo
Artist’s concept of an asteroid mining operation (NASA)

Perhaps that’s a bit too much of a stretch, though.  After all, it might turn out to be cheaper to cut some kind of deal with a country that has the resources we need, but lacks the capability to extract them on their own.

Let’s consider energy independence, then.  Solar power is often criticized because it doesn’t work when the weather is bad or at night.  The Sun is always shining in space, though.  The fundamental technology already exists where we could collect solar power in space and beam it to the ground on a frequency largely transparent to the atmosphere.

It just hasn’t been demonstrated on a large enough scale to be useful – yet.  The National Space Security Office has done studies showing how space-based solar power could allow the military to provide clean, safe, on-demand power to forward-deployed bases.  In some places, the cost per kilowatt-hour for the military today is 20 times what we pay stateside.  Space-based solar would also eliminate costly and dangerous powerplant fuel convoys.

The European Space Agency sponsored a study that showed a powersat system could pay back its energy costs of being established within its first year of operation.  However, the problem is that the cost of launch to orbit is still very high, so much so that the commercial space industry tends to be very conservative.  It would be hard to get a powersat initiative going without a large first customer.

Advances in technology are reducing the size and increasing the efficiency of solar panels, though.  New designs currently in development could provide as much power as all eight arrays on the International Space Station on a single array a fraction the size.  Such high-density production will also be useful for electric propulsion systems that are orders of magnitude more efficient than chemical propulsion in space.

blog post photo
Artist’s concept of a powersat (NASA)

Author Ben Bova laid out a possible roadmap to a powersat future, though, in 2008.  The United States built its giant hydroelectric dams through public-private partnerships where private investors were backed by low-interest, long-term loans guaranteed by the government.

A similar program where NASA demonstrates the technology for in-space applications and turns over mass production to private industry for such customers as the military could be just the thing to spur the creation of this new industry – an inherently high-tech field with direct security and economic benefits to the country.

If you’re still skeptical about solar, though, there is always nuclear power to consider.  To minimize crew exposure to cosmic radiation and dramatically reduce transit times (perhaps to intercept an asteroid or comet), nuclear-based propulsion in space may be required.  This will require the development of safe, simple, but highly-productive nuclear reactors suitable for launching into orbit and propelling spacecraft.  Such advanced nuclear power would certainly be useful for terrestrial applications, as well.

In partnership with the Department of Energy and private industry, NASA could play a key role in developing lightweight, but safe, nuclear reactors that would reduce our dependence on fossil fuels for energy production.

NASA has published its successfully commercialized technology since 1976.  However, Tang and Velcro remain – incorrectly, I might add – the “spinoffs” captured in the public psyche.  I think this is because we have not been successful as a community at designing our leading programs and missions to simultaneously contribute to solving America’s most pressing issues.  Once we do that, I don’t think there will be any question of NASA’s relevance.

Just as President Jefferson sent Lewis and Clark out into the frontiers of America to see what opportunities awaited us, NASA is the Congressionally-empowered civil agent of the government to explore our opportunities in “the High Frontier”, gather the knowledge and develop the technology we need to protect ourselves and our investments, and foster America’s best utilization of space resources.

blog post photo
Artist’s concept of an aerobraking Orbital Transfer Vehicle (NASA)

Cross-posted at A World With No Boundaries

Why explore space? [Part I of II]

There is a strong sentiment held by some these days that America doesn’t necessarily need to explore space or that, if it does, we should leave it entirely to the private sector.  I’d like to discuss why I think space exploration is important and the role I see for government in that endeavor.  For this first post, I’ll talk about the “why”.

The fundamental reason I think we should explore space at all is pretty straightforward, actually.  We are almost certain that we know what killed the dinosaurs.  Sixty-five million years ago, an object 10-15 kilometers in size impacted the Earth near the present-day town of Chicxulub on the Yucatan Peninsula.  For a sense of perspective, this asteroid or comet was almost as big around as the Inner Loop/610.

The Chicxulub collision was more powerful than one billion Hiroshima bombs and left a crater more than 100 miles in diameter, now mostly covered by the Gulf of Mexico.

blog post photo
Artist’s rendition of the Chicxulub impact (NASA)

While there are a variety of collolary theories regarding other environmental stresses that led up to or followed the impact, the scientific consensus to-date is that this was what triggered the mass extinction that ended the reign of the dinosaurs.  Sedimentation layers around the world that correspond to the time of the impact have much higher concentrations than normal of iridium, an element that is rare in the Earth’s crust and relatively abundant in asteroids and comets.

The impact itself would have generated dust clouds and sulfuric aerosols that blocked the Sun’s light and devastated plant life.  This triggered a catastrophic collapse in the food chain.  We have also found evidence for the tsunamis generated when the asteroid hit the water, such as marine sand in places where there were no seas, at the time.  The heat pulse from the impact and the re-entry of debris cast out into space would have also ignited firestorms across the planet, dumping pollutants into the atmosphere.

Even if there were multiple impacts that triggered other calamities, as some scientists suggest, the Cretatious-Tertiary extinction event stands as a lesson for us in the fundamental value of having both knowledge and understanding of the workings of our solar system.  As one science fiction author once astutely put it, the dinosaurs died because they didn’t have a space program.

A study of Earth’s geological record will show the evidence of past impacts, some perhaps even larger than that which killed the dinosaurs.  An asteroid or comet impact is believed by some scientists to have played a role in the immense Permian-Triassic extinction event 250 million years ago, though we are much less certain about its causes.

However, we do know that 96% of all marine species and 70% of land-based vertebrates were wiped out.  The Permian extinction is also the only known mass extinction of insect species.

In more recent times, we have actually observed dramatic collisions between asteroids and comets and other planets in our solar system.  Perhaps the most notable example is from July 1994, when Comet Shoemaker-Levy 9 was seen striking Jupiter after having been broken up by the planet’s immense gravitational influence.

The actual impacts occurred on a side of Jupiter pointed away from Earth at the time.  The Galileo probe, though, was already en route to Jupiter for its planetary science mission and observed the collision as it happened.  The first impact created a fireball of nearly 43,000 degrees Fahrenheit and with a plume nearly 2000 miles high.  The Hubble Space Telescope even saw the fireball plume rise over the edge of Jupiter’s visible disc.

blog post photo
Hubble Space Telescope imagery of the fireball (NASA)

Twenty-one impacts were observed over six days.  The largest created a dark spot in Jupiter’s clouds approximately the diameter of the Earth and released energy equivalent to 600 times all of the nuclear weapons on the planet – combined.

Closer to home, the Tunguska event of 1908 is believed to be an airburst of an asteroid or comet fragment a few miles above the surface of the Earth.  The blast was likely equivalent to the most powerful thermonuclear weapons ever built – between 10 and 30 megatons of TNT – and destroyed over 800 square miles of Siberian forest.  Such an impact could easily devastate a metropolitan area.

Asteroids and comets, of which over 1000 are classified as “Potentially Hazardous Objects,” are not our only worry, though.  The Ordovician extinction, approximately 440 million years ago, is theorized by some scientists to have been caused by a gamma ray burst from a relatively nearby supernova.

In such an event, one study showed that a 10-second gamma ray beam could destroy half of the Earth’s ozone and expose life on the surface to intense prompt UV radiation.  Following the event, the Earth would be vulnerable to increased absorption of solar radiation, as well.  This could have catatrophic effects on the food chain, because of mass die-offs of plants and plankton, and lead to widespread disruption of the biosphere.

blog post photo
Artist’s rendition of a gamma-ray burst (NASA)

Put simply, there are things out there in space that can kill us and our only defense is to go out there, study and understand those threats, and develop strategies for mitigation.

Human beings tend to cluster in groups for mutual benefit and survival.  It is an evolutionary strategy that usually works well for us.  However, there are always a few who break out on their own to explore new areas and establish new groups.  Most do not succeed.  However, those that do ensure the continued survival of our species and introduce tremendous growth.

If fact, I would argue that the United States itself is a perfect example of that.  Our nation was founded by people who left the Old World behind to start anew and make something special for themselves.  That is how the original Thirteen Colonies were started.  That is how “the West was won.”  As a nation, we have been at our best when we are out on the frontiers.

Now, we live in a world with a globalized economy.  The leadership of the United States is in question.  History is starting to repeat itself.  Like many great nations before us, we are becoming fat and complacent, more concerned with entertainment than accomplishment.  However, we still have advantages in resources and ingenuity.

blog post photo
Artist’s rendition of an exploration mission to an asteroid (NASA)

I can think of no more fitting legacy for the United States than to lead the way in what Gerard K. O’Neill, physicist and space advocate, called “the High Frontier.”  The problems of space travel, asteroid and comet deflection, and the colonization of other worlds are immense.  We are, quite literally, just scratching at the surface.

The balance here on Earth is tenuous, though.  Every human being that has ever lived and died has done so here on this planet.  All of our proverbial eggs are in one basket.  There are many threats to that balance from within, such as global climate change, natural disasters, and our own propensity for violent political and economic struggle.  We cannot assume that our fortune at living in a time relatively conducive to human civilization will continue indefinitely.

Just as the United States escaped the majority of the devastation of World War II to become the world’s technological and economic powerhouse, I think it likely that our descendants on other worlds will one day be called to do the same by avoiding calamity here on Earth.

So, what role is there for the government in all of this?  That will be the subject of Part II.

Cross-posted at A World With No Boundaries.

2005 YU55

Radar image of asteroid 2005 YU55. Image credit: NASA/Cornell/Arecibo

Kind of following up Marian’s post about asteroids, scientists at JPL have “imaged” the near-earth asteroid 2005 YU55 using the Arecibo Radar Telescope in Puerto Rico back on April 19, 2010.

Orbital track of 2005 YU55. Courtesy JPL

The asteroid at one time was listed as a potential threat because its orbital path brings it very close to Earth on occasion, a few passes of which could not be ruled out for possibility of impact.  It takes a number of observations to be able to predict an orbit.  It follows that the predictions can only be as accurate as the observed position.  You can appreciate when looking through a telescope how difficult it can be to get a very precise position.  Sure you can get very close but even a small error can add up over a long distance.

With the Arecibo Radar Telescope the scientists were able to track the asteroid with very fine accuracy.  The image above was take on April 19, 2010 and while described as ghostly (which it is) the resolution is 25 feet (7.5 meters) per pixel, not bad for an object 1,300 feet (400 meters) across.  The asteroid also appears spherical in shape.  By tracking the asteroid from April 19th to the 21st , scientists were able to reduce the uncertainties in the orbit by half and we know there no chance of a collision for at least 100 years.  More observations will enable longer term predictions.

Source

Kabinett des Grotesken ("Cabinet of the Grotesque"), Berliner Medizinhistorisches Museum der Charité, Spiegel Online


My friend, German journalist Michael Kneissler, just sent me a link to an article and an amazing short film celebrating the world famous Berliner Medizinhistorisches Museum der Charité on its 300th birthday, prompted by a new exhibition at the museum entitled "Charité--300 years of medicine in Berlin."

Following is an excerpt from the article--found on Spiegel Online and entitled "Kabinett des Grotesken" ("Cabinet of the Grotesque")--via a sloppy Google Translation:

Human malformations, surgical instruments, the Dildo-box of a sex researcher: The Collection of the Berlin Charité shows the dazzling variety of medical research. To mark its 300th anniversary Clinic presents highlights from the world famous now its archive.

Hands upset, steal: impossible. In the showcases the treasures of the Lord Virchow are safe. Very safe. And yet the guards sneak past every now and again. Ready to intervene immediately. They know that the temptation is to press for the issue "Charité - 300 Years of Medicine in Berlin" on the trigger...

Brains, livers, lungs, testes, ovaries removed - from the different and peaceful perished miserably, preserved in jars for viewing, Educate and quenching. An exhibition of the Interior, without taboos. Even human fetuses are also included. One with legs fused together, one with eyes grown together in the middle of the forehead. A Cyclops. Unreal and yet real.

Virchow himself called this collection - eagerly gathered for medical students and the public in order to warn of an unhealthy lifestyle - his "favorite child", for some visitors to the house if these preparations now the favorite image design: "Krass," it escapes some...

This dazzling looking exhibition is on view at the Berlin-based Medizinhistorisches Museum der Charité until February 2011; very much hope to see it before it comes down!

You can read the whole article and watch the wonderful video walk-through on the same page (just click the play button!) by clicking here. You can find out more about the museum in English by clicking here. Image above is drawn from the video.

Thanks so much to Michael Kneissler for sending this along!

The Limits of Therapy

From the SENS Foundation: "To date, the dominant therapeutic strategy for both specific age-related diseases and (to the extent that it has been contemplated) the degenerative biological aging process itself, has been based on altering metabolic pathways. Biomedical research has centered on the detailed understanding of pathways seen to be contributing to disease etiology or pathogenesis, and the identification of putatively dysfunctional components hormones, receptors, enzymes, cytokines, etc), which are then targeted for manipulation by small molecules or other means in hopes of normalizing function and thereby alleviating symptoms or slowing progression of pathology. ... there is a critical flaw in the unconsciously-drawn analogy between its use in the development of therapies to manage specific diseases, and its potential for the treatment of the degenerative aging process. Unlike most non-communicative diseases, degenerative aging is not the result of the dysfunction of metabolic pathways, but of the the undesirable long-term side-effects of their normative biochemistry. Put another way: biological aging is the pathological result of perfectly-functioning, [healthy] metabolic processes. ... Thus, transposing the conventional drug-development pathway onto the aging process necessarily entails interfering with the normal metabolism - and doing on an indefinite basis, from the day that a 'patient' first begins therapy until his or her death. But of course, those same pathways evolved to ensure survival and fitness, and their existence and the normal mode of regulation are the very basis of ordinary health and function. We interfere with the intrinsic operation of such pathways at our peril."

View the Article Under Discussion: http://www.sens.org/node/747

Read More Longevity Meme Commentary: http://www.longevitymeme.org/news/

Thoughts on Rejuvenation and Alzheimer’s Vaccines

A detailed examination of recent progress from the SENS Foundation: "Recent years have seen both substantial progress, and significant frustration, in the preferred regenerative engineering approach to the treatment and prevention of Alzheimer's disease (AD), and the eventual regeneration of genuinely youthful cognitive function: immunotherapeutic clearance of beta-amyloid (AmyloSENS). ... results appear to many to commend an earlier window of opportunity for intervention, before concomitant [damage] and neuronal losses have made the removal of beta-amyloid alone insufficient for cognitive rescue. Early intervention might also maximize the therapeutic window for vaccination, preventing the burden of beta-amyloid neuropathology from ever reaching levels so high as to interact with other forms of aging damage in already frail and immunosenescent people." Present work on immune therapies for clearing unwanted biochemical junk from the body looks promising - there is every sign that today's advances will broaden into a general technology platform for this purpose. Researchers will be able to develop therapies that can be applied incrementally throughout life to remove the age-related gunk like beta-amyloid before it rises to dangerous levels.

View the Article Under Discussion: http://www.sens.org/node/757

Read More Longevity Meme Commentary: http://www.longevitymeme.org/news/

Thoughts on Rejuvenation and Alzheimer's Vaccines

A detailed examination of recent progress from the SENS Foundation: "Recent years have seen both substantial progress, and significant frustration, in the preferred regenerative engineering approach to the treatment and prevention of Alzheimer's disease (AD), and the eventual regeneration of genuinely youthful cognitive function: immunotherapeutic clearance of beta-amyloid (AmyloSENS). ... results appear to many to commend an earlier window of opportunity for intervention, before concomitant [damage] and neuronal losses have made the removal of beta-amyloid alone insufficient for cognitive rescue. Early intervention might also maximize the therapeutic window for vaccination, preventing the burden of beta-amyloid neuropathology from ever reaching levels so high as to interact with other forms of aging damage in already frail and immunosenescent people." Present work on immune therapies for clearing unwanted biochemical junk from the body looks promising - there is every sign that today's advances will broaden into a general technology platform for this purpose. Researchers will be able to develop therapies that can be applied incrementally throughout life to remove the age-related gunk like beta-amyloid before it rises to dangerous levels.

View the Article Under Discussion: http://www.sens.org/node/757

Read More Longevity Meme Commentary: http://www.longevitymeme.org/news/

U.S. Hospital Social Media List Includes More Than 600 Hospitals

280 YouTube Channels
382 Facebook pages
470 Twitter Accounts
82 Blogs

Twitter is the easiest and blogs are the most difficult and time-consuming social media channel, respectively. This explains the difference in numbers to some extent - 470 Twitter Accounts vs. only 82 Blogs.

References:
Hospital Social Media List Update. Found In Cache.
http://ebennett.org/hsnl_03_28_10
Image source: OpenClipArt.org, public domain.

Posted at Clinical Cases and Images. Stay updated and subscribe, follow us on Twitter and connect on Facebook.


Approach to evaluation and management of syncope in adults – BMJ Review

Syncope is common in all age groups, and it affects 40% of people during their lifetime, usually described as a "faint" or "blackout".

Neurally mediated syncope, which is benign, is the most common cause

Cardiac syncope as a result of arrhythmias or structural cardiopulmonary disease is more common with increasing age. Cardiac syncope is associated with increased mortality and must be excluded.

Brain imaging, carotid Doppler ultrasound, electroencephalography, and chest radiography are often not needed in patients with syncope.

References:

An approach to the evaluation and management of syncope in adults. BMJ 2010;340:c880.
http://www.bmj.com/cgi/content/short/340/feb19_1/c880
Image source: Illustration of the human brain and skull. Wikipedia, Patrick J. Lynch, medical illustrator, Creative Commons Attribution 2.5 License 2006.

Posted at Clinical Cases and Images. Stay updated and subscribe, follow us on Twitter and connect on Facebook.


ChemSpider SyntheticPages

I recently mentioned the Reaction Attempts project, which aims to collect organic chemistry experiments - especially those that are "failed", in progress or somehow incomplete.

For reactions where the desired product has been obtained and fully characterized, ChemSpider SyntheticPages also offers a very convenient publication vehicle. As I mentioned previously there is a need for enabling the publication of single experiments, especially when these are unlikely to become part of a traditional article.

We are in the process of submitting suitable reactions from the UsefulChem project to CS|SP. This will require some re-formatting of procedures and characterization data as they currently appear in the lab notebook.

Here is an example of one of our Ugi reactions: SyntheticPage 406 (UCEXP176C)


A nice feature of these pages is the automatic rendering of 2D structures upon hovering on top of chemical names.


Here are a few more reasons to use ChemSpider SyntheticPages:

* ChemSpider SyntheticPages takes you directly to a procedure. When you get a hit - you get a procedure.
* ChemSpider SyntheticPages provides information that may not generally be found elsewhere, such as frequently encountered problems, trouble-shooting tips, the number of times the reaction has been carried out, scale-variation etc.
* ChemSpider SyntheticPages is the only interactive chemistry database. Information is constantly updated and validated by comments from the user community (Peer Review in the Public Domain™).
* ChemSpider SyntheticPages can provide you with the most up-to-date method, we aim for 95% of submissions to be processed within 48 hours of submission.
* ChemSpider SyntheticPages is free of charge.

[Disclaimer: I am a member of the editorial group at CS|SP]

Skin Drawings

These ink drawings by Lynn Palewicz are really cool looking. Here’s what she has to say about the collection.

This series of drawings describes a relationship between touch, tension, and surface.  Each piece uses the body to distort a variety of images and marks drawn onto skin.  Pinches, creases, and scratches marked onto its surface function as drawing elements alongside these penned images and marks.  Photography more than documents the performance of these drawings; it disorients the viewer’s relationship to the body and represents the skin as a drawing surface.

Check the rest out here!

[via beautifuldecay]

Squamous cell carcinoma and Epstein Bar

You did not mention ear insuflation. I thought you would since the ears are so close to the tongue. Is there a reason that the ear insuflations would not do the trick for this cancer of the tongue?

Also she lives 15 minutes away from me. Is there a way I could ozonate water for her and the ozone would hold for the day till she drank it? I once heard that you can do something with magnets to keep the water ozonated for a little while. I do not remember all the information on it.

Also you mentioned rinsing her mouth with ozonated water. How much ozonated water should she drink?

We are in total agreement that her body is run down.

thanks a lot Read more...



Immunice for Immune Support

Still growing strong

Kittiwakes now on eggs!
Mother Mallard with chicks

Guillemots on the cliffs
Sunday 2nd May comments:
Its been all go over since I last updated – a combination of staff shortage (the majority of the team have been away on a boat training course) as well as induction days for two new members of the team, weather and the onset of the hectic breeding season has resulted in a fewer blog posts than I would have liked!” However fear not, I’m back and expect regular updates from hereon in. So what’s happened since last weekend…read on…
The breeding season continues with pace as the first Kittiwake eggs were discovered on 26th April and more have been discovered since. The significance – the first Kittiwake eggs in April since 1989 - the early start to the season continues! Ringed Plovers have re-nested following their egg predation in mid-April, whilst four Pied Wagtail nests have been discovered across the islands – one pair using the traditional nest site in St.Cuthbert’s Chapel.

Its not all about eggs – Shags have now got young – the first chicks started hatching on 30th April. However the Terns have yet to settle, although numbers are increasing nightly with over 1,2000 Sandwich, 1,000 Arctic’s and 36 Little Terns graced the islands roost last night. Migration through the islands has continued to bring some exciting discoveries with highlights over the last few days shown below.

Monday 26th April: Shoveler 4 in Kettle, Little Tern 1 (first of the year), Swallow 31N, Dunnock 1, Black Redstart female on Brownsman, Song Thrush 1, Wheatear 8, Willow Warbler 8, Chiffchaff 2, Whitethroat 1, Rook 2 over and Reed Bunting male on Inner Farne

Tuesday 27th April: Peregrine 1 immature, Tufted Duck male north, Red-breasted Merganser female north, Red-throated Diver 4N, Grey Heron 1 west, Common Scoter 42N, Yellow Wagtail male east over inner group, Dunnock 2, Wheatear 2, Blackbird male, Willow Warbler 3, Chiffchaff 1 and Linnet 3.

Wednesday 28th April: Pink-footed Goose 290N, Whimbrel 1, Common Sandpiper 1, Swallow 6N, Ring Ouzel 1 male lingering on Inner Farne (3rd of the spring), Yellow Wagtail male over, Wheatear 25, Dunnock 1, Blackbird male, Redstart 2 (pair), Blackcap male, Whitethroat 2, Willow Warbler 12, Chiffchaff 3, Linnet 1.

Thursday 29th April: Wood Pigeon 1, Wheatear 27, Whitethroat 2, Sedge Warbler 1, Willow Warbler 10, Chiffchaff 2, Blackcap 1 female with very pale wing panels (like a Black Redstart!).

Singapore Cleanliness order and super efficiency

We landed late afternoon to Singapore and were instantly dazzled by the airport took one look around and knew our fortunes had changed after India The place was spotless no touts and linked by an underground system MRT to the city. We instantly loved the place. We found the hostel with ease perfectly situated in the Bugis Area the previous red light district until the government buldozed

PictonAbel TasmanBarry townFranz Josef

Wow what an amazing few days Since my last update I went to a place called Abel Tasman which is the second largest national park in new zealand we got there pretty late after a few pit stops for shopping and a wine tasting session in Marlborough mmmm. Mum it turns out I dont like chardonnay at all not just that one we had but the other wines were goooood Abel Tasman was fantastic it was rea