The University of Chicago Department of Medicine

Robert Grossman,PhD, Professor of Medicine and Co-Chief Section of Computational Biomedicine and Biomedical Data Science has been named the Frederick H. Rawson Professor effective January 1, 2017. Dr. Grossman is an expert in data intensive computing and its applications to biology, medicine and healthcare. His research focuses on bioinformatics, data science, and data intensive computing. Dr. Grossman currently serves as Co- PI of the NCI Genomics Data Commons.

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After nearly two decades of unsuccessful attempts, researchers from the University of Chicago Medicine and the Cincinnati Childrens Hospital Medical Center have created the first mouse model for the most common form of infant leukemia. Their discovery, published in the Nov. 14, 2016, issue of Cancer Cell, could hasten development and testing of new drug therapies.

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This year Kovler Diabetes Center celebrates its 10th anniversary, capping a decade of cutting edge treatment and research that has made the University of Chicago Medicine a world leader in diabetes care.

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Although many cancer patients respond favorably to immunotherapies such as nivolumab and pembrolizumab, most patients do not. Blame for treatment failures is usually attributed to so-called cold tumors, those that do not attract T-cell infiltration and may lack key T-cell targetsthe mutated proteins known as neoantigens.

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I know that we can save many more women from dying from breast cancer, oncologist Olufunmilayo Olopade says, leaning forward in her chair. Olopade, who goes by Funmi, is sitting in her office at the end of a long day, surrounded by stacks of paper on her desk and shopping bags on the floor, but she sounds like she could be addressing the World Health Organization. The drugs are there, the women are out there, she says. Whats missing, in her view, is a will to diagnose and treat people, wherever they live.

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The number of deaths from breast cancer have declined significantly over the last several decades. However, many populations within the U.S. and across the globe have not benefited from these improvements in mortality as much as other groups have. This unequal burden of cancer felt by specific population groups, also known as disparities, is a major healthcare challenge and one that hits home. In Chicago, the most recent figures show the breast cancer death rate among black women is 40 percent higher than that of white women.

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The role of the gut microbiome in human health keeps expanding, but some microbes are slow to reveal their secrets.

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The University of Chicago Medicines Successful Aging and Frailty Evaluation (SAFE) Clinic, located in the nearby South Shore community on the South Side, cares for some of the most vulnerable patients throughout the city..

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Dr. Everett Vokes recently announced the creation of the new Section of Computational Biomedicine and Biomedical Data Science , making it the 15th subspecialty section within the Department of Medicine. The new Section will provide an intellectual home for faculty whose research interests encompass computational biomedicine; biomedical data science (data science and its applications to biology, medicine and healthcare), and biomedical informatics (bioinformatics, translational informatics, and clinical/medical informatics) and will be co-led by Robert L. Grossman, PhD and Andrey Rzhetsky, PhD.

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Matthew Sorrentino, MD, Professor of Medicine in the Section of Cardiology, has been appointed as Vice Chair for Clinical Operations effective immediately. In this new role, Dr. Sorrentino will assist in leading the Department of Medicines clinical programs and serve as the key departmental representative with the UCM and BSD on issues relating to the Departments outpatient, inpatient and offsite practices.

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Type 2 diabetes is an insidious disease because its most damaging effects dont show up for years. A patient may have her ups and downs from day to day, but the risk of heart disease, kidney disease, damage to the retinas and other circulatory problems builds over years with the accumulated stress of high blood sugar levels.

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Obstructive sleep apnea a disorder that affects nearly one out of four people between the ages of 30 and 70 is a common cause of high blood pressure. In the Aug. 17, 2016, issue of the journal Science Signaling, researchers based primarily at the University of Chicago describe the signaling cascade that leads to this form of hypertension and suggest ways to disrupt those signals and prevent elevated blood pressures.

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By probing the differences between two farming communitiesthe Amish of Indiana and the Hutterites of South Dakotaan interdisciplinary team of researchers found that specific aspects of the Amish environment are associated with changes to immune cells that appear to protect children from developing asthma.

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The University of Chicago Department of Medicine

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