The 60 best internet radio stations

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WCPE

Branding itself online as The Classical Station, WCPE is an eminently likeable classical music station from North Carolina. Its been listener-supported for over 30 years, and continues to pay for most of its operating costs from pledges and donations which is a sure-fire sign of a station that knows and respects its audience. Their playlists tend towards the popular - rather than the obscure or experimental - end of the classical spectrum, with regular appearances by Mozart, Beethoven, Bach, Handel and Rachmaninoff.

AM 1710 ANTIOCH OTR

When Im trying to explain the peculiar magic of Internet radio to a non-convert, I tend to use this marvellous little station from Illinois as an example. Run by a radio enthusiast and techie called Jay Lichtenauer, it plays a huge variety of American radio dramas from the 1930s, 40s and 50s, scheduled by genre (family comedy, spy stories, science fiction, frontier stories, etc) and complete with ads for now-defunct household products and cigarette brands. Tuning in for the first time is rather like stepping into an audio time machine; but the pleasures of listening extend beyond this novelty factor: the shows themselves, taken from the golden era of American radio drama are often miniature masterpieces of suspense, intrigue and entertainment.

AUDIOBOO

This useful website and phone app, which is evidently aiming to become the Twitter of the audio world, allows users to record, upload, share and discover sound files. These can be anything from homemade rants about Premiership football teams to short clips from BBC and commercial radio shows to full concert recordings of the likes of Ella Fitzgerald and Nina Simone.

RADIO REVERB

This sparklingly creative community radio station from Brighton is a bona fide reason to be cheerful. With a schedule that takes in everything from theatre-going to jazz to electronic dance music, its a welcome reminder that you dont need commercial or license fee backing to make great radio.

ART INTERNATIONAL RADIO

Operating out of the beautiful Clocktower Building the heart of the New York art scene of the 1970s and 80s AIR is one of the most smartly curated arts stations on the planet. All music, interviews, documentaries and experimental pieces are also available on demand via its website.

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The 60 best internet radio stations

YouTube's silky smooth 60FPS video is now ready for viewing

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YouTube promised that you'd see many videos playing at a brisk 60 frames per second this year, and it looks like the streaming site has made good on its word. While there were a few 60FPS test clips in the spring, you can now see regular uploads with silky smooth motion. There are some fairly strict conditions you'll need to meet before you see these high-quality videos, mind you. You'll have to watch in Chrome at HD resolution, and the content providers naturally have to upload 60FPS content in the first place. Provided all the stars align, though, you're in for a good time -- it's not often that you can watch video game replays at the same quality that you'd get from a console in your living room.

[Image credit: MK8 Records, YouTube]

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YouTube's silky smooth 60FPS video is now ready for viewing

4 Ways Developers Say Apple Can Improve The Mac App Store

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Last week Realmac Software released RapidWeaver 6, the long-awaited upgrade to its flagship web design software. RapidWeaver has long been a staple app for those Mac users who want the simplicity of a drag and drop WYSIWYG website builder combined with more advanced tools for those that dont mind digging into code.

RapidWeaver's popularity has only increased in the years since Apple discontinued its popular iWeb web design software, and Apple has spotlighted the software in its Mac App Store from time to time. Thats why it was something of a shock when, after the announcement of the immediate availability of RapidWeaver 6 last week, Realmac also announced the new software would not be available via the Mac App Store.

Eliminating a popular distribution channel seems like an odd move for any developer, but Realmac is just the latest Mac dev to hold off releasing their apps on the Mac App Store. Bare Bones Software recently decided not to release BBEdit 11 on the MAS and Panic Software has opted not to sell its popular Coda app on the MAS any longer.

Just what is going on? Many major Mac developers say the Mac App Store is in need of changes to make it truly worthwhile for developers to sell their apps there. Heres what three of them told me what Apple needs to do to fix things.

All apps have bugs. Thats just the nature of software. When you are talking about bugs in an iOS app, its rare that any bug requires an immediate fix. After all, most mobile apps today are still not true productivity tools that we solely rely on. The same cant be said for desktop apps, which oftentimes are the tools we cannot do our jobs without. Even a moderate bug often needs to be fixed right away or it can seriously hinder a users ability to get work done.

Through traditional distribution channels its always been quick and easy to issue bug fixes. Once a bug is discovered and fixed, the developer could quickly upload the new build of the app to their website (or push it out through in-app software update mechanisms). This way a user could oftentimes get the fix for their problem within hours of a major bug being discovered. This isnt the case for apps distributed through the Mac App Store, however. Any app changes--including small bug fixes--must be approved by Apple, which can take a week or more. According to Dan Counsell, founder of Realmac Software, this was the primary reason the company decided not to release RapidWeaver 6 on the Mac App Store.

RapidWeaver 6 is a huge update with a large number of third parties updating their add-ons to work with this new version, Counsell says. We obviously wanted the update to go as smoothly as possible for our customers and should a critical bug appear during the launch we wanted to be able to fix it with hours, not days or weeks. If RapidWeaver was on the Mac App Store and we had to submit an update it could take at five days or more to go through the review process--I felt that wasnt fair for all our loyal customers.

Needless to say, Counsells primary suggestion for how Apple can improve the Mac App Store is to speed up review times--something virtually every developer I spoke to agreed with. As one developer who wished to remain anonymous said, Mission critical apps require mission critical bug fix times. You cant get that with apps through the Mac App Store.

But there was an additional reason Realmac chose to hold off RapidWeaver 6s launch on the Mac App Store: a lack of upgrade pricing for owners of older versions of the app. This too has long been a chief complaint among Mac developers. Apple understandably wants to make the software purchasing experience as simple as possible for users, but developers are tied down by the economic realities of what it costs to develop new versions of their apps and also the need to make past users feel like they are getting a good deal.

Id love to see upgrade pricing, however Apple seem very reluctant and at this point Im not sure itll ever happen, says Counsell. Its something customers and developers repeatedly ask for, but Apple seem fixed on driving down the price of apps.

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4 Ways Developers Say Apple Can Improve The Mac App Store

Testimonial 1 for Energy Medicine by Elaine: Bridging The Gap between Medical & Spiritual – Video

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Testimonial 1 for Energy Medicine by Elaine: Bridging The Gap between Medical Spiritual
http://www.ReikiTherapybyElaine.com ~ Lauren M. #39;s Testimonial for Energy Medicine Reiki Therapy by Elaine can be found on yelp: ...

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"3D in Medicine" A free 2-hour live seminar with an international panel of experts – Video

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"3D in Medicine" A free 2-hour live seminar with an international panel of experts
Join us as we provide a live seminar on how medical scanning works, dentistry in the 21st century, how to take your own medical scans and 3D print them, and meet the boy and the 3D print shop...

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FDA awards grants to stimulate drug, device development for rare diseases

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The U.S. Food and Drug Administration today announced it has awarded 15 grants totaling more than $19 million to boost the development of medical device, drug, and biological products for patients with rare diseases, with at least a quarter of the funding going to studies focused solely on pediatrics.

The FDA awards grants for clinical studies on safety and/or effectiveness of products that could either result in, or substantially contribute to, approval of the products.

The FDA is in a unique position to help those who suffer from rare diseases by offering several important incentives to promote the development of products for rare diseases, one of which is this grants program, said Gayatri R. Rao, M.D., director of the FDAs Office of Orphan Product Development. The grants awarded this year support much-needed research in difficult-to-treat diseases that have little, or no, available treatment options.

The program is administered through the FDAs Orphan Products Grants Program. This program was created by the Orphan Drug Act, passed in 1983, to promote the development of products for rare diseases. Since its inception, the program has given more than $330 million to fund more than 530 new clinical studies on developing treatments for rare diseases and has been used to bring more than 50 products to marketing approval.

A panel of independent experts with experience in the disease-related fields reviewed the grant applications and made recommendations to the FDA.

The 2014 grant recipients are:

For the grants program therapies, a disease or condition is considered rare if it affects less than 200,000 persons in the United States. There are about 7,000 rare diseases and conditions, according to the National Institutes of Health. In total, nearly 30 million Americans suffer from at least one rare disease.

The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nations food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.

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See the Birth of Modern Medicine in These Photos

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More ABC US news | ABC Health NewsCopy

The early days of modern medicine, before penicillin and anesthesia, can seem gruesome by today's standards. But archivist and collector of medical photography, Dr. Stanley Burns, thinks its important to look back at the early days of medicine understand how far modern medicine has come in just over 100 years.

Burns, the founder and archivist of the Burns Archive, has lots of evidence about how crude early medical treatments could be at the beginning of the last century. From electroshock for blindness to scoliosis cures that look torturous, the haunting photographs from the Burns archive can be beautiful and scary reminders of how rudimentary medicine was just a century ago.

The doctors 100 years ago were just as smart and interested in helping their patients as we are today, Burns told ABC News. The problem was they labored under inferior knowledge and technology.

Burns photography archive includes thousands of pictures ranging from early medical operations to Civil War-era photos of wounded soldiers, some of which were featured in a show at the Metropolitan Museum of Art in New York.

His newest exhibition is decidedly more macabre. Its a collection of memorial photography, which are pictures of the deceased for loved ones, mainly from the turn of the 19th century.

The photographs of the posed deceased are being featured at the Morbid Anatomy Museum in Brooklyn, New York, until this January.

Cinemax

PHOTO: On "The Knick" an ambulance circa 1900 is a simple horse drawn carriage.

Earlier this year, Burns incredible knowledge about the birth of modern medicine has been utilized at his newest side-job -- medical adviser on the Cinemax drama The Knick.

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See the Birth of Modern Medicine in These Photos

IBM Watson lends analytic power to genomic medicine

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Summary: IBM has detailed new marching orders for the Watson Analytics cognitive computing platform helping doctors uncover the patterns that cause disease.

Speaking today at the 2014 Cleveland Clinic Medical Innovation Summit, IBM chairman Ginni Rometty detailed new marching orders for the Watson Analytics cognitive computing platform helping doctors uncover the patterns that cause disease.

With help from the Lerner Research Institute's Genomic Medicine Institute, researchers at the Cleveland Clinic will use IBM's Watson Genomics Analytics to harness the powers of big data to spot genetic indicators for certain cancers. From there, doctors can formulate individualized treatment plans based on the patient's DNA.

IBM says Watson has a unique ability to overcome the "needle in the haystack" challenge that often arises with genomic mapping. Doctors need to be able to correlate data from genome sequencing to reams of medical journals, new studies and clinical records while also treating the patient with the best available procedures.

That's where Watson comes in. The Watson Genomics Analytics application is a combination of Watson's cognitive system, deep computational biology models and IBM's public cloud infrastructure SoftLayer.

With its ability to rapidly review massive databases and continually learn with each new patient scenario, researchers and doctors hope Watson will allow them to increase the number of patients who have access to the tailored care options.

"The potential for leveraging the capabilities of Watson's cognitive computing engine in personalized medicine could not be timelier," said Dr. Charis Eng, chair and founding director of the Lerner Research Institute's Genomic Medicine Institute. "Clinicians will benefit from the knowledge and insight provided by Watson in the care of their patients."

This isn't the first foray Watson has made into healthcare. The super computer has also been utilized by the Mayo Clinic, as well as through IBM's partnerships with healthcare providers such as WellPoint and Memorial Sloan-Kettering. IBM even says the latest pilot initiative with the Cleveland Clinic is an extension of on-going programs with the renowned cancer treatment center that aim to aid in the advancement of big data in healthcare.

"Using Watson's cognitive computing capabilities, Cleveland Clinic aims to offer cutting-edge care to millions of patients," said Rob Merkel, VP of IBM Watson Group Healthcare Leader. "We're excited by our continued partnership with Cleveland Clinic. Together we aim to advance a new era of cognitive computing that will aide in the acceleration of new discoveries and bring forward new breakthroughs in personalized medicine."

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IBM Watson lends analytic power to genomic medicine

Three-company collaboration announced for advancement of aging research

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PUBLIC RELEASE DATE:

28-Oct-2014

Contact: Michael Petr michael.petr@insilicomedicine.com InSilico Medicine, Inc. @InSilicoMeds

Through this unique partnership, the Baltimore-based Insilico Medicine and Lethbridge-based CCARL will provide expertise in aging research and build on the personalized medicine and drug discovery platforms OncoFinder and GeroScope to develop new systems for age-related diseases. During the first phase of collaboration, Insilico Medicine and CCARL drug discovery and personalized medicine efforts will focus on Multiple Sclerosis (MS) and Plantbiosis will simultaneously validate the system, experimentally.

Through its agreement with the University of Lethbridge, Plantbiosis has access to state of the art gene expression, sequencing, epigenetic research, metagenomic, cell line banks and cell culture facilities. It also brings over five years of experience in data acquisition, mining and processing and complements access to infrastructure with a team of trained scientists and technicians.

"Aging is a true global pandemic, which kills more people daily than any other disease and extending productive longevity will not only decrease pain and suffering, but will also provide a significant boost to the global economy. However, before we can look for interventions that may be effective in slowing down the aging processes, we need to understand the systemic changes in defensive and pathological states in many age-related diseases. We started this journey in cancer and now we are going after other diseases that will help us gather the data for a grand plan of attack on aging. And while we are already helping improve decision making in clinical oncology with OncoFinder, we are happy to collaborate on development of a platform to better personalize disease modifying drugs for treatment of multiple sclerosis", said Olga Kovalchuk, MD/PhD, MBA, CEO of Canada Cancer and Aging Research Laboratories, Ltd.

During the course of collaboration, the companies will build a statistical database of tissue-specific changes in signalome, interactome and epigenome in a variety of age-related diseases and normal aging to understand the intricate interplay between pathologic and defensive states.

"We are very happy to partner with CCARL and Plantbiosis led by the highly-productive ambitious and driven scientists, who are looking beyond classical approaches to age-related disease research and are going after the grand prize, which is aging. They are looking to change the biomedical paradigm from treatment to prevention and are the only companies in Canada with the vision and tools to do that", said Alex Zhavoronkov, PhD, CEO of Insilico Medicine, Inc.

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Three-company collaboration announced for advancement of aging research

USF trustee committee endorses downtown Tampa medical school

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TAMPA A group of University of South Florida trustees on Thursday endorsed building a new medical school in downtown Tampa, a key recommendation that could quickly move the proposed project forward.

"I believe this location will really transform both USF and the city of Tampa in profound ways," said Dr. Charles Lockwood, senior vice president for USF Health and dean of the Morsani College of Medicine.

The five trustees who oversee USF Health's medical and educational programs voted to build the new Morsani College of Medicine on an acre of land in downtown that Tampa Bay Lightning owner Jeff Vinik has offered to donate for the project.

"This is bigger than baseball," Mayor Bob Buckhorn told the trustees.

Then he added: "Please do it. I don't want to have to turn off the water at the university."

Vinik is on the verge of remaking the southern end of downtown Tampa, and a new medical school fits the kind of high-end development he wants to build around the home of his hockey team, the Amalie Arena.

The projected cost of the new, 12-story medical school is between $150 million to $163 million. USF has assembled around $130 million in funding and would need to find other sources to complete the project. The new medical school office tower could have 287,824 square feet of usable space.

Lockwood presented a plan for building not just a new medical school, but also a medical office building next door and an 1,800-car parking garage that would serve both.

The next step would be for the full board of trustees to vote on the health committee's recommendation at its next meeting, Dec. 4. The full board generally gives great weight to the committee's recommendation.

USF has just a few months to make a decision. The university needs to decide where to put the new medical school so it can ask the Board of Governors for tens of millions in state funding. That board meets Jan. 21-22 at the University of North Florida in Jacksonville.

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USF trustee committee endorses downtown Tampa medical school

Four years in, payment model lowers medical spending, improves care

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PUBLIC RELEASE DATE:

29-Oct-2014

Contact: David Cameron david_cameron@hms.harvard.edu 617-432-0441 Harvard Medical School @HarvardHealth

A new study suggests that a plan that uses global budgets for health care, an alternative to the traditional fee-for-service model of reimbursement, has improved the quality of patient care and lowered costs during the four years since it was first implemented.

Researchers from Harvard Medical School'sDepartment of Health Care Policy have analyzed claims data from the first four years of Blue Cross Blue Shield of Massachusetts' Alternative Quality Contract (AQC), a global budget program in which health care provider organizations were given a budget to care for patients insured under the health care plan. Such a model contrasts with widely used fee-for-service systems, where providers are reimbursed for each medical service they deliver.

"These results are encouraging, because, throughout our health care system, spending is growing at an unsustainable rate and our quality of health care is not as high as it should be," said study author Zirui Song, HMS clinical fellow in medicine and resident at Massachusetts General Hospital. "Global budgets and other payment reform initiatives provide incentives for physicians and hospitals to think collectively about population health and to focus on coordination of care."

The study compares Blue Cross members who have a primary care physician (PCP) as part of an AQC contract to a control group of commercially insured individuals across eight northeastern states (Connecticut, Maine, New Hampshire, New Jersey, New York, Pennsylvania, Rhode Island and Vermont) who also have designated PCPs in their health plans.

Comparing the financial and quality results of the AQC with this control group was important, the researchers said, because it accounts for more general trends locally and nationallyshowing that the AQC achieved savings over and above what was happening in similar health care environments.

Though trends were similar prior to the AQC, from 2009-2012 Massachusetts AQC enrollees had smaller increases in medical spending over the first four years of the contract than similar individuals in other states, researchers said. Patients who received care under the AQC also experienced larger improvements in measures of quality of care such as the percentage of diabetes patients who received eye exams or blood sugar monitoring, or measures of how well patients controlled their blood pressure or cholesterol, the researchers said.

"The health care system is transforming as we move to new payment models," said Michael Chernew, Leonard D. Schaeffer Professor of Health Care Policy at HMS. "While there's certainly more to learn, preliminary results suggest that this transformationmay improve quality and at least in some settings reduce spending."

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Four years in, payment model lowers medical spending, improves care

Fallen Liberty – For Whom the Bell Tolls (Metallica Cover) RCGC Coffee Haus – Video

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Fallen Liberty - For Whom the Bell Tolls (Metallica Cover) RCGC Coffee Haus
Fallen Liberty recorded on 10/27/14 at Rowan College at Gloucester County #39;s Coffee Haus. Band consists of Tyler Barrett on guitare and vocals, Peter Salugao on guitar and Nick Menna on drums.

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Fallen Liberty - For Whom the Bell Tolls (Metallica Cover) RCGC Coffee Haus - Video