The Road to Mandalay with Vantage Deluxe World Travel 2014. – Video

Posted on by


The Road to Mandalay with Vantage Deluxe World Travel 2014.
This is a trip of a lifetime from Bangkok to Myanmar,Yangon,Bago,and Cruise from Prome- Thayet-Magway-Salay-Monywa-Yandabo-Bagan-Mandalay. Thanks to all trvelers for sharing opinion from ...

By: Trips Reminder Ukkritsteven

See the original post:

The Road to Mandalay with Vantage Deluxe World Travel 2014. - Video

How adult fly testes keep from changing into ovaries

Posted on by

4 hours ago

New research in flies shows how cells in adult reproductive organs maintain their sexual identity. The study, publishing online on November 13 in the Cell Press journal Developmental Cell, also identified a mutation that can switch the cells' sexual identity. The findings could lead to new insights on how to alter cells for therapeutic purposes.

Sperm and eggs are made from germ cells, but instructions from their neighboring support cellscalled somatic cellsare also essential for their development. By studying the formation of sperm in fruit flies, which is remarkably similar to the process that occurs in people, investigators serendipitously found a mutation that gave testes a very unusual appearance. "Rather than becoming sperm, germ cells were stuck at an early stage, and they were surrounded by support cells that looked suspiciously like those belonging in an ovary," says senior author Dr. Erika Matunis of The Johns Hopkins School of Medicine. Her research team found that the mutation blocked the function of a specific gene in the stem cells that becomes support cells in the testis, causing the fruit flies to change from a male to a female identity.

The research is the first to show that adult stem cells actively maintain their sexual identity. The mutation the investigators found causes the stem cells in males to switch their sexual identities and start making support cells that belong in the ovary. This ultimately derails the production of sperm. "The molecules that govern this process are highly conserved, which suggests that similar mechanisms could operate in human testes," says Matunis.

The changes seen in this study are an example of transdifferentiation, or the conversion from one cell type to another. The topic is of considerable interest because promoting transdifferentiation in a directed manner may be useful for regenerating damaged organs or tissues. Doing so will require a thorough understanding of how cell fate conversions are regulated. "We are excited to have a powerful genetic system for studying transdifferentiation of stem cells at the mechanistic level," says Matunis. The research might also provide insights into how cells transform from a normal state to a cancerous one.

Explore further: Surprise: Lost stem cells naturally replaced by non-stem cells, fly research suggests

More information: Developmental Cell, Ma et al.: "The Jak-STAT target Chinmo prevents sex transformation of adult stem cells in the Drosophila testis niche" http://www.cell.com/developmental-cel 1534-5807(14)00628-5

Journal reference: Developmental Cell

Provided by Cell Press

Johns Hopkins researchers have discovered an unexpected phenomenon in the organs that produce sperm in fruit flies: When a certain kind of stem cell is killed off experimentally, another group of non-stem cells can come out ...

Read more:

How adult fly testes keep from changing into ovaries

Why Do We Keep Dissing Chabad's Spirituality?

Posted on by

Orthodox Outreach Is Getting Something Right By Jay Michaelson

Published November 13, 2014.

Its been a year since the Pew Research Center released its Portrait of Jewish Americans. I havent counted how many words have been written about the report since that time, from the Forwards e-book to endless handwringing by the OJC (Organized Jewish Community). But somewhere along the line, Pew definitely turned into Phew. As in, Phew, thank God thats over.

But Ive been struck, over the year of reflections and recommendations, at the relative absence of my own primary vector of Jewish engagement: spiritual practice.

One example, which I came across because its author and I are acquaintances, is Rabbi Dan Smoklers excellent strategy to attract Jewish college students. (Dans piece matters more than most, since he is chief innovation officer at Hillel.) I am on board with his six-point plan: social groups, Jewish mentors, encounters with different kinds of Jews, Torah study, the Jewish calendar, and Jewish service. All good.

But Dan waves off the successes of Aish HaTorah and Chabad on campus, saying most Jews are unlikely ever to move into any sector of the Orthodox camp. That may be true, but its still worth asking why these groups succeed in the first place.

Surely, the odds should be stacked against them. Chabad shlichim are generally quite sincere, open and friendly. But they often look funny, talk funny, and do funny things like put tefillin on strangers. Their practices seem out of step with contemporary mores in many areas, not least the different privileges accorded to women and men.

And yet, as Dan briefly notes, they and other Orthodox/ultra-Orthodox outreach programs often do quite well on campus. Even correcting for the free food.

The fact is, there is something Chabad Houses offer that Hillels dont: effective spiritual practice, and people who believe in its efficacy.

Note the word effective. Of course, Hillels, and mainstream synagogues, offer various forms of religious observance. You can sit (and stand) in traditional services all week long, if you like. But what do these services do, exactly?

Read more here:

Why Do We Keep Dissing Chabad's Spirituality?

Russia: The new ISS crew expect an ‘intense’ 169-day space mission – Video

Posted on by


Russia: The new ISS crew expect an #39;intense #39; 169-day space mission
Video ID: 20141111-014 W/S ISS crew, Star City SOT, Anton Shkaplerov, Russian cosmonaut (in Russian): "Every new flight is similar to the previous of course, but has its own different tasks...

By: RuptlyTV

Originally posted here:

Russia: The new ISS crew expect an 'intense' 169-day space mission - Video

Lego Batman 3 Beyond Gotham Walkthrough Part 4 – Space Station Infestation (Let’s Play Commentary) – Video

Posted on by


Lego Batman 3 Beyond Gotham Walkthrough Part 4 - Space Station Infestation (Let #39;s Play Commentary)
Lego Batman 3 Beyond Gotham Gameplay Walkthrough Part 1 - Pursuers in the Sewers (Let #39;s Play Commentary) https://www.youtube.com/watch?v=Ew38A316F2w Lego Batman 3 Beyond Gotham ...

By: Tetra Ninja

Read more:

Lego Batman 3 Beyond Gotham Walkthrough Part 4 - Space Station Infestation (Let's Play Commentary) - Video

LEGO BATMAN 3 – BEYOND GOTHAM – PART 5 – SPACE SUITS YOU! (HD) – Video

Posted on by


LEGO BATMAN 3 - BEYOND GOTHAM - PART 5 - SPACE SUITS YOU! (HD)
Thank you for Watching, hope you enjoyed! Thank you for rating and commenting below, it is always appreciated 😀 Leave your opinions and suggestions in the comments section below. ===Awesome ...

By: Blitzwinger

See the rest here:

LEGO BATMAN 3 - BEYOND GOTHAM - PART 5 - SPACE SUITS YOU! (HD) - Video

LEGO Batman 3: Beyond Gotham – Space Station Infestation – Part 6 (Xbox One Gameplay) – Video

Posted on by


LEGO Batman 3: Beyond Gotham - Space Station Infestation - Part 6 (Xbox One Gameplay)
The Asian Guy Gamer and The Asian Kid Gamer are playing LEGO Batman 3: Beyond Gotham on the Xbox One!!! Be sure to hit the "LIKE" button for more LEGO Batman 3: Beyond Gotham!!! LEGO ...

By: The8Bittheater

See more here:

LEGO Batman 3: Beyond Gotham - Space Station Infestation - Part 6 (Xbox One Gameplay) - Video

LEGO BATMAN 3 – BEYOND GOTHAM – PART 6 – SPACE STATION INFESTATION! (HD) – Video

Posted on by


LEGO BATMAN 3 - BEYOND GOTHAM - PART 6 - SPACE STATION INFESTATION! (HD)
Thank you for Watching, hope you enjoyed! Thank you for rating and commenting below, it is always appreciated 😀 Leave your opinions and suggestions in the comments section below. ===Awesome ...

By: Blitzwinger

Excerpt from:

LEGO BATMAN 3 - BEYOND GOTHAM - PART 6 - SPACE STATION INFESTATION! (HD) - Video