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stem cells panama Search Results StemCell Therapy

Plans to Create Russian National Orbital Station Confirmed

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Russia's space agency Roscosmos is currently looking at plans to create a national space station that may be included in the new Federal Space Program, Roscosmos head Oleg Ostapenko said Monday. "I confirm that we are looking at this variant as a likely direction," Ostapenko said.

Ostapenko added that the high-altitude station is also being considered as a base for Russia's lunar program. "There is also this variant, we are currently considering it," he said.

In September, Roscosmos said it was planning to launch a full-scale moon exploration program in 2016-2025. According to the reports, the new orbital station will also be used to test manned spacecraft for the lunar mission. Spacecraft will first be delivered to the station, and then continue to the Moon.

In May, Russian Deputy Prime Minister Dmitry Rogozin said that Russia was considering dropping out of the ISS program, and re-direct its funding into more promising space projects.

A Russian space engineering source close to matter told Russian media in November that the country was looking to build its own orbital station, with the project set to begin in 2017. The station will use modules constructed for the International Space Station (ISS), the source added.

Roscosmos Will Decide on New Super-Heavy Rocket Design in January 2015 Russia's space agency Roscosmos will decide on the design of the country's new super-heavy rocket in January 2015, Roscosmos chief Oleg Ostapenko said Monday.

"We have already received blueprints from three leading space rocket enterprises. A panel of experts has already started considering them, and we will select the winner <...> in January," he told reporters.

Roscosmos is looking to develop a super-heavy carrier rocket to be used in Russia's lunar program. Andrei Mazurin, who heads one of the space agency's departments, told RIA Novosti in October the launch vehicle would be able to lift up to 80 tons of cargo into space. In the long term, a rocket capable of carrying 130 to 160 tons could be developed, he added.

Russia's largest existing rocket, the Proton, can launch payloads of up to 20 tons. The modular Angara rocket is also under development and comes in several versions, the largest of which is planned to send up to 35 tons into orbit.

Russian Space Agency's 2015 Budget Unchanged Despite Economic Downturn Despite the current downturn in the Russian economy, the government has no plans to cut the 2015 budget of the national space agency, Roscosmos chief Oleg Ostapenko told reporters Monday.

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Plans to Create Russian National Orbital Station Confirmed

Boeing Covers Groundwork In Second Milestone

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December 15, 2014

Image Caption: Concept of the floor of the CST-100 assembly facility that Boeing envisions at Kennedy Space Center. Credit: Boeing

Provided by NASA

The momentum of certifying American space transportation systems capable of carrying astronauts to the International Space Station continued on pace as NASA took a comprehensive look at all of Boeings ground-based system designs. This Ground Segment Critical Design Review marks the second milestone in the companys Commercial Crew Transportation Capability (CCtCap) contract, NASAs Launch America initiative designed to return human spaceflight launches to the United States and end our reliance on Russia.

The three-week-long review covered Boeings plans for constructing and processing its Crew Space Transportation System, called the CST-100, in a former orbiter processing facility at NASAs Kennedy Space Center in Florida, where Boeing will process its CST-100. It also covered the development of a nearby mission control center that would be the hub of the companys engineering operations.

Along with facility designs, we looked at the operation processes, said Dave Allega, a lead in the Ground and Mission Operations Office of NASAs Commercial Crew Program. How would they be using those facilities? What is the flow? How are they going to build up their new spacecraft, get it ready to fly, put it on the launch vehicle and then operate it once it is there? Then, after landing, how will they go recover it and turn it around to go and do it again?

A few dozen engineers, along with safety and health and human performance experts, took a deep dive into the various elements here on the ground that would support a crew mission to the station. Even astronauts who could one day fly aboard the CST-100 participated in the review of these critical elements, such as how Boeing would test flight hardware, and assemble and integrate its spacecraft to the United Launch Alliance Atlas V rocket. They even looked at the equipment that would move the integrated stack to Cape Canaveral Air Force Stations Space Launch Complex 41.

ULA has a long history of successful uncrewed commercial launches, and now they are highlighting what is different about flying a crew, said John Mulholland, Boeing Commercial Crew Program Manager.

Another critical piece of this review included how Boeing plans to train astronauts prior to missions and how the company will monitor crew members during all phases of the flight. For example, the CST-100 spacecraft simulator the company built at its Houston Product Support Center will start to see a lot of action as more pilot-in-the-loop demonstrations are performed and crew training begins.

The CST-100 will be a more simple vehicle to operate than the space shuttle, but the automation is complicated in and of itself, so we need to understand that automation and so does the crew, said Allega. When Boeing trains our astronauts, they will have to balance simplicity, and giving the crew everything they need to know to manually operate the spacecraft just in case something goes wrong.

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Boeing Covers Groundwork In Second Milestone

Russia may build its own space station to rival ISS

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The International Space Station is a great example of how different nations can work together to create something pretty awesome. In this case a habitable location orbiting the Earth. And it was made possible by the combined efforts of the US, European, and Russian space agencies. However, growing political tensions could mean we get a second space station, only this one would be a purely Russian affair.

Russias actions with regards to Ukraine has seen relations with the West stretched to breaking point and trade sanctions put in place. The crumbling relationship is impacting all areas of government, including those departments working on space tech. With that in mind, the Russian Federal Space Agency (Roscosmos) is starting to view its own alternative to ISS as a real possibility.

Russias Mir manned space station orbited the Earth from 1986 to 2001.

Oleg Ostapenko, head of Roscosmos, has confirmed that a Russian space station is currently being considered, and it would likely form a key part of a mission to visit the Moon. Its not as simple as just greenlighting the project, however. With Russia under trade sanctions and having an economy expected to go into recession in 2015, there may not be enough money available to fund such a project.

Even if a station cant be built by Russia alone, the Russian government may block plans to extend the life of ISS from 2020 to 2024. Although, its unclear what they could actually do beyond protesting if the other parties with an interest in the station decide to ignore them.

ISS has been a success and is widely viewed as a positive creation of man. Space doesnt belong to any one nation, and it seems right that any future developments of this nature should continue to be collaborations regardless of whats happening back on Earth. Hopefully that means an eventual, multi-national ISS v2.0.

Now read: Stunning video of Earth from space made from 80GB of images

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Russia may build its own space station to rival ISS

Russia considers building its own space station to rival ISS: report

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Russian state space agency Roscosmos is considering building its own space station, RIA news agency quoted its chief as saying on Monday, underlining how international tensions are affecting space co-operation.

Such a project would rival the International Space Station, an orbiting laboratory that involves 15 nations including Russia and the United States. Moscow has cast doubt on the ISSs long-term future as ties with Washington plummet over Ukraine.

I confirm we are considering such an option. This is a possible direction of development, RIA quoted Roscosmos head Oleg Ostapenko as saying when asked about whether Russia has plans to develop it own space station.

He said such a space station could become a key part of Russian missions to the moon.

It is not clear how such a project would be financed as Russia is widely expected to enter recession next year and the economic crisis is aggravated by Western sanctions over Russias policy in the Ukraine crisis.

Washington wants to keep the $100-billion ISS in use until at least 2024, four years beyond the previous target. But a Russian government official said in May that Moscow would reject Washingtons request to prolong its operations.

The Russian space station Mir, launched by the Soviet Union in 1986, operated until 2001 and President Vladimir Putin is now seeking to reform Russias once-pioneering space industry after years of budget cuts and a brain drain that led to a series of embarrassing and costly failed launches in recent years.

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Russia considers building its own space station to rival ISS: report

Russia considers building its own space station: Report

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MOSCOW - Russian state space agency Roscosmos is considering building its own space station, RIA news agency quoted its chief as saying on Monday, underlining how international tensions are affecting space co-operation.

Such a project would rival the International Space Station (ISS), an orbiting laboratory that involves 15 nations including Russia and the United States. Moscow has cast doubt on the ISS's long-term future as ties with Washington plummet over Ukraine.

"I confirm we are considering such an option. This is a possible direction of development," RIA quoted Roscosmos head Oleg Ostapenko as saying when asked about whether Russia has plans to develop it own space station.

He said such a space station could become a key part of Russian missions to the Moon.

It is not clear how such a project would be financed as Russia is widely expected to enter recession next year and the economic crisis is aggravated by Western sanctions over Russia's policy in the Ukraine crisis.

Washington wants to keep the US$100 billion ISS in use until at least 2024, four years beyond the previous target. But a Russian government official said in May that Moscow would reject Washington's request to prolong its operations.

The Russian space station Mir, launched by the Soviet Union in 1986, operated until 2001 and President Vladimir Putin is now seeking to reform Russia's once-pioneering space industry after years of budget cuts and a brain drain that led to a series of embarrassing and costly failed launches in recent years.

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Russia considers building its own space station: Report

AMIGA OCS Galaxy Fight The Incredible Space Flight CRACK THE MOVERS KICK 1 2 ALL SYSTEMS DOWN MEMO – Video

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New "Brain" for Space Shuttle Engine is No Technological Flashback to the '80s

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December 15, 2014

Provided by Megan Davidson, NASAs Marshall Space Flight Center

Take a look at your current devices. Can you imagine swapping that smartphone for a gigantic cellphone from the 1980s? Surfing the Internet with dial-up speed? Working out to your favorite music with a cassette player?

Todays technology is better, faster and more innovative. People have to keep up with the rapidly changing times, and so does the brain for the RS-25 rocket engine.

Image: The engine controller unit allows communication between the vehicle and the engine, relaying commands to the engine and transmitting data back to the vehicle. Engineering model controllers are being tested at the Marshall Center and Stennis Space Center. Credit: NASA/MSFC

The engine controller unit on the RS-25 formerly known as the space shuttle main engine helped propel all of the space shuttle missions to space. It allows communication between the vehicle and the engine, relaying commands to the engine and transmitting data back to the vehicle. The controller also provides closed-loop management of the engine by regulating the thrust and fuel mixture ratio while monitoring the engines health and status.

Just like the ever-evolving computer, the engine controller unit needed a refresh to provide the capability necessary for four RS-25 engines to power the core stage of NASAs new rocket, the Space Launch System (SLS), to deep space missions. Thecore stage, towering more than 200 feet tall with a diameter of 27.6 feet, will store cryogenic liquid hydrogen and liquid oxygen that will feed the vehicles RS-25 engines.

You cant put yesterdays hardware on todays engine, especially since many parts of the shuttle-era engine controller unit arent even made anymore, said Russ Abrams, avionics subsystem manager in the SLS Liquid Engines Office at NASAs Marshall Space Flight Center in Huntsville, Alabama. Marshall manages the SLS Program for the agency. We need the most updated control systems for this engine to meet SLS specifications and take us to places weve never been before in space.

Controller development is based heavily on the recent development experience with the J-2X engine controller. An engineering model RS-25 controller is being tweaked and tested at Marshall. At one of the centers test facilities, engineers are simulating the RS-25 in flight, using real engine actuators, sensors, connectors and harnesses.

A second engineering model controller and RS-25 engine also recently were installed on the A-1 test stand at NASAs Stennis Space Center near Bay St. Louis, Mississippi. Pending final preparation and activation work, the engine test series is anticipated to begin in 2015.

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New "Brain" for Space Shuttle Engine is No Technological Flashback to the '80s

Are Redheads more prone to Bullying? NoBullying Article Released Today

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London, UK (PRWEB) December 15, 2014

With red haired people thought to be an obvious minority worldwide, the world is now only beginning to take note of the bullying of redheads or ginger haired people. NoBullying attempts to understand the phenomena of bullying redheads in an article released today.

According to this article, published by the BBC in August 2014, Shows such as South Park have triggered a significant increase in bullying against people with red hair. In one of their episodes they created a holiday called Kick a Ginger Day. This was essentially a holiday where physical abuse against red heads was tolerated because redheads have no soul. Even though most adults can look at this and understand that this is simply comedy meant to poke fun at the ridiculous thought process behind bullying, it has actually started to turn this into a real issue as many younger viewers did not understand this and went on to bully their red haired classmates.

The source article also alludes to the ongoing estimation that almost half of all women with red hair will face bullying or discrimination at some point in their life due to their red hair, ginger haired women tend to face sexual innuendo or insulting derogatory statements about their red hair.

The best way for schools to handle bullying behavior is to confront it head on. By getting everyone involved in taking a stand against bullying and shaming, schools have a better chance of minimizing this abusive behavior on their campus. As adults, teachers, parents and school staff need to lead the way in demonstrating an acceptance of all students in their classrooms, regardless of differences in appearance, race, nationality or physical and mental abilities. Even friendly teasing of students with red hair needs to stop. Teachers who tease their students pave the way for bullies to pick up where they leave off. By treating all children the same, teachers send the signal that everyone is accepted for who they are.

Students can do their part to stop redhead bullying by befriending redheaded students and making them feel welcomed in class and social activities. All students need to feel like they belong. By accepting redheads into their circle of friends and standing up against abusive behavior, students can help break the bullying cycle. Less bullying makes for a more inspiring school environment thats conducive to learning.

Ciaran Connolly, Co Founder of NoBullying says We hear from parents of bullied red haired children that it seems logical to get the children to change their hair color to avoid bullying, making changes about your appearance wont solve any bullying problem.

He elaborates Bullies use physical appearance as an excuse to bully others, if the victim changes a physical aspect the bully will find something else to use as a reason for bullying, it is an ongoing circle of aggression that can only be broken with kindness, education and strict anti bullying policies.

He added that parents and teachers should make a point to educate the younger generations about the sad outcome of neglecting online safety and photos safety. According to Connolly, it is quite imperative to press for more firm laws condemning all acts of bullying and harassment.

NoBullying.com features many pages dedicated to parents, teens, teachers, health professionals as well as posts related to cyber safety and the latest news about law making concerning curbing Bullying worldwide as well as inspirational Bullying Poems and famous Bullying Quotes.

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Are Redheads more prone to Bullying? NoBullying Article Released Today

'Radiogenetics' Seeks to Remotely Control Cells and Genes

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Newswise Its the most basic of ways to find out what something does, whether its an unmarked circuit breaker or an unidentified gene flip its switch and see what happens. New remote-control technology may offer biologists a powerful way to do this with cells and genes. A team at Rockefeller University and Rensselaer Polytechnic Institute is developing a system that would make it possible to remotely control biological targets in living animals rapidly, without wires, implants or drugs.

Today (December 15) in the journal Nature Medicine, the team describes successfully using electromagnetic waves to turn on insulin production to lower blood sugar in diabetic mice. Their system couples a natural iron storage particle, ferritin, to activate an ion channel called TRPV1 such that when the metal particle is exposed to a radio wave or magnetic field it opens the channel, leading to the activation of an insulin producing gene. Together, the two proteins act as a nano-machine that can be used to trigger gene expression in cells.

The method allows one to wirelessly control the expression of genes in a living animal and could potentially be used for conditions like hemophilia to control the production of a missing protein. Two key attributes are that the system is genetically encoded and can activate cells remotely and quickly, says Jeffrey Friedman, Marilyn M. Simpson Professor head of the Laboratory of Molecular Genetics at Rockefeller. We are now exploring whether the method can also be used to control neural activity as a means for noninvasively modulating the activity of neural circuits. Friedman and his Rensselaer colleague Jonathan S. Dordick were co-senior researchers on the project.

Other techniques exist for remotely controlling the activity of cells or the expression of genes in living animals. But these have limitations. Systems that use light as an on/off signal require permanent implants or are only effective close to the skin, and those that rely on drugs can be slow to switch on and off.

The new system, dubbed radiogenetics, uses a signal, in this case low-frequency radio waves or a magnetic field, to heat or move ferritin particles. They, in turn, prompt the opening of TRPV1, which is situated in the membrane surrounding the cell. Calcium ions then travel through the channel, switching on a synthetic piece of DNA the scientists developed to turn on the production of a downstream gene, which in this study was the insulin gene.

In an earlier study, the researchers used only radio waves as the on signal, but in the current study, they also tested out a related signal a magnetic field to activate insulin production. They found it had a similar effect as the radio waves.

The use of a radiofrequency-driven magnetic field is a big advance in remote gene expression because it is non-invasive and easily adaptable, says Dordick, who is Howard P. Isermann Professor of Chemical and Biological Engineering and vice president of research at Rensselaer. You dont have to insert anything no wires, no light systems the genes are introduced through gene therapy. You could have a wearable device that provides a magnetic field to certain parts of the body and it might be used therapeutically for many diseases, including neurodegenerative diseases. Its limitless at this point.

The choice to look at insulin production was driven by the equipment they used to generate the radio waves and magnetic fields. Because the coil that generates these signals is currently small i.e; only three centimeters in diameter, it was necessary to anesthetize the mice to keep them still. Since anesthesia can repress the production of insulin, the hormone that reduces blood sugar, Stanley and her colleagues designed the genetically encoded system to replace the insulin that is normally reduced by anesthesia in mice.

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'Radiogenetics' Seeks to Remotely Control Cells and Genes

Study: Novel agent decreases neuropathic pain in patients with type 2 diabetes

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15-Dec-2014

Contact: Terry Lynam tlynam@nshs.edu 516-465-2640 North Shore-Long Island Jewish (LIJ) Health System

MANHASSET, NY -- Molecular Medicine, a peer-reviewed biomedical journal published by the Feinstein Institute Press, published the results of a new study reporting clinically significant pain reduction in type 2 diabetic patients. In an exploratory study conducted by Araim Pharmaceuticals, a biotech company developing novel treatments for chronic diseases, investigators also observed improvements in metabolic control in patients administered ARA 290. ARA 290 is a peptide engineered to activate the innate repair receptor, a receptor discovered by Araim scientists, which is only expressed following tissue damage or stress.

In the initial study, patients were administered ARA 290, a novel, first-in-class drug, daily for 28 days, with the purpose of evaluating its efficacy in treating neuropathic pain, a common condition among diabetics. When ARA 290 is administered, the repair receptor is activated and subsequently turns off inflammation and turns on the body's natural repair system. The short half-life of ARA 290, coupled with the restricted expression of the innate repair receptor, functions as a dual safety system to avoid potential side effects.

"The results from this study indicate a major breakthrough in the treatment of diabetes," said Kevin J. Tracey, MD, president of the Feinstein Institute for Medical Research and Editor of Molecular Medicine. "Over the years, Molecular Medicine has prided itself on publishing groundbreaking papers with implications on the broader medical community, and we're proud to have a potential disease-modifying solution to diabetes featured in the current issue."

The clinically significant results and excellent safety profile support Araim's development strategy of two future studies in 2015. First, metabolic improvement will be studied in type 2 diabetics with moderate kidney damage. Second, neuropathic pain reduction will be assessed in a multi-center proof of concept trial in type 1 diabetics. Both phase 2 clinical trials will be conducted in the United Kingdom, and patients will be dosed daily for six months to allow time for adequate tissue repair.

"We're excited to be on the cusp of the first diabetic disease modifier that demonstrates the potential to repair the complications of diabetes systemically," said Anthony Cerami, PhD, CEO of Araim Pharmaceuticals." Dr. Cerami developed the HbA1c diagnostic test, the current gold standard for diagnosing diabetes.

###

The research was supported in part by a grant from the Netherlands Institute for Regenerative Medicine. Read the full report in http://www.molmed.org.

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Study: Novel agent decreases neuropathic pain in patients with type 2 diabetes

Molecular "Hats" Allow in vivo Activation of Disguised Signaling Peptides

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Newswise When someone you know is wearing an unfamiliar hat, you might not recognize them. Georgia Institute of Technology researchers are using just such a disguise to sneak biomaterials containing peptide signaling molecules into living animals.

When the disguised peptides are needed to launch biological processes, the researchers shine ultraviolet light onto the molecules through the skin, causing the hat structures to come off. That allows cells and other molecules to recognize and interact with the peptides on the surface of the material.

This light-activated triggering technique has been demonstrated in animal models, and if it can be made to work in humans, it could help provide more precise timing for processes essential to regenerative medicine, cancer treatment, immunology, stem cell growth, and a range of other areas. The research represents the first time biological signals presented on biomaterials have been activated by light through the skin of a living animal, and could provide a broader platform technology for launching and controlling biological processes in living animals.

Many biological processes involve complex cascades of reactions in which the timing must be very tightly controlled, said Andrs Garca, a Regents Professor in the George W. Woodruff School of Mechanical Engineering at Georgia Tech and principal investigator for the project. Until now, we havent had control over the sequence of events in the response to implanted materials. But with this technique, we can deliver a drug or particle with its signal in the off position, then use light to turn the signal on precisely when needed.

Supported by the National Science Foundation and the National Institutes of Health, the research is reported in the December issue of the journal Nature Materials. It resulted from collaboration between scientists from Georgia Tech and the Max-Planck Institute in Germany through the Materials World Network Program.

When biomaterials are introduced into the body, they normally stimulate an immune system response immediately. But the researchers used molecular cages like hats to cover binding sites on the peptides that are normally recognized by cell receptors, preventing recognition by the animals cells. The cages were designed to detach and reveal the peptides when they encounter specific wavelengths of light.

During the five-year project, the research team which included Ted Lee and Jose Garcia from Georgia Tech and Aranzazu del Campo from Max-Planck modified peptides that normally trigger cell adhesion to present the molecular cage in order to disguise them. They showed that disguised peptides introduced into animal models on biomaterials could trigger cell adhesion, inflammation, fibrous encapsulation, and vascularization responses when activated by light. They also showed that the location and timing of activation could be controlled inside the animal by simply shining light through the skin.

The work involved numerous controls to ensure that the triggering observed by the researchers was actually done by exposure of the peptides not the light, or the removal of the protective cage. The researchers also had to demonstrate that the hats were stable enough that they didnt come off spontaneously, but only when the link between the molecular cage and the peptide was severed by the ultraviolet light.

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Molecular "Hats" Allow in vivo Activation of Disguised Signaling Peptides

Help For Medicine Donated To Carolina Family Healthcare By Charles Myrick of ACRX – Video

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Silverlakes Urgent Care Receive Tribute & Free Medicine Coupons By Charles Myrick of ACRX – Video

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