Global warming blamed for worst Pacific coral bleaching on record

MAJURO, MARSHALL ISLANDS The Marshall Islands is experiencing its worst-ever coral bleaching as global warming threatens reefs across the entire northern Pacific, scientists said Monday.

Marine researchers said an El Nino weather pattern had been developing in recent months, raising ocean temperatures and stressing delicate coral reefs.

The worst coral bleaching event ever recorded for the Marshall Islands has been occurring since mid-September, Karl Fellenius, a Majuro-based marine scientist with the University of Hawaii, said.

C. Mark Eakin, manager of the U.S. National Oceanic and Atmospheric Administrations Coral Reef Watch program, said recent observations showed the problem was widespread across the vast waters of the northern Pacific.

Major bleaching was seen in Guam and the Commonwealth of the Northern Marianas Islands, the northwestern Hawaiian Islands (NWHI), the Marshall Islands, and Kiribati, he said. Thermal stress levels set new record highs in CNMI and the NWHI and we saw the first widespread bleaching event in the main Hawaiian Islands.

Fellenius said coral bleaching was a naturally occurring phenomenon but not on the scale currently being seen: While bleaching can occur on very hot days in pools of water with little circulation (such as) very low tides on reef flats, it has become a global problem due to greenhouse gas emissions causing elevated temperatures under climate change.

He said sea surface temperatures had been on average half to a full degree Celsius higher than normal for months, adding, This does not seem like a lot but it makes a big difference to corals.

Fellenius said the last major bleaching event was in 1997, when an exceptionally strong El Nino system affected about a quarter of the worlds coral reefs.

He said indications were that the latest episode had affected up to 75 percent of smaller corals and 25 percent of the larger varieties at some sites in the Marshalls. He said the bleached coral was becoming covered with algae, hindering its chances of recovery.

The World Meteorological Organization raised the alarm about rising sea temperatures this month on the sidelines of U.N. climate talks in Lima, saying 2014 was set to be the hottest year on record, consistent with man-made climate change. What is particularly unusual and alarming this year are the high temperatures of vast areas of the ocean surface, WMO chief Michel Jarraud said.

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Global warming blamed for worst Pacific coral bleaching on record

San Juan Islands still the place to be for prime winter chinook action

(Capt. Chris Long of Jolly Mon Charters holds two nice winter chinook. Photo courtesy of Kevin Klein.)

Here is a winter chinook fishing report from San Juan Islands by Kevin Klein with the Puget Sound Anglers Fidalgo-San Juan Islands Chapter:

Blackmouth fishing is pretty darn good in the Islands right now. Everybody seems to be using something different, and catching fish.

Bait, spoons, hootchies, you name it, theyre biting it. That usually means theres a lot of fish swimming around. As long as it looks like a 4-inch herring, itll get bit. We had good luck on the Silver Horde Tailwagger last weekend. Its really become a mainstay in our arsenal. Gotta have the Wagger in the spread!

The 2015 Roche Harbor Salmon Classic is SOLD OUT! Wow, a sell out before Christmas. Coming on the success of the Resurrection Derby, anglers are itchin to get out there and compete for cash. The Roche Derby is the next stop on the Northwest Salmon Derby series. We will see you out there February 5th.

Should be a good one. This year Roche Harbor and Island Boat Rentals are sponsoring two teams who will be taking returning veterans out to fish as part of the Salmon for Soldiers program. Much thanks for supporting our troops.

Tickets are now on sale for the 11th annual Frank Wilson Memorial Blackmouth Derby. Enter at Kings Marine in Friday Harbor. This cool lil local derby runs from February 1st until April 12th. $1000 first prize, and fun included. All proceeds go to San Juan Island Emergency Services.

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San Juan Islands still the place to be for prime winter chinook action

Human primordial cells created in the lab

A cell programming technique developed at the Weizmann Institute turns them into the earliest precursors of sperm and ova

IMAGE:These are clusters of human embryonic stem cells that were differentiated to an early germ cell (PGC) state (colored cells). Each color reveals the expression of a different gene. (l-r)... view more

Credit: Weizmann Institute of Science

Groups at the Weizmann Institute of Science and Cambridge University have jointly managed the feat of turning back the clock on human cells to create primordial germ cells - the embryonic cells that give rise to sperm and ova - in the lab. This is the first time that human cells have been programmed into this early developmental stage. The results of their study, which were published today in Cell, could help provide answers as to the causes of fertility problems, yield insight into the earliest stages of embryonic development and potentially, in the future, enable the development of new kinds of reproductive technology.

"Researchers have been attempting to create human primordial germ cells (PGCs) in the petri dish for years," says Dr. Jacob Hanna of the Institute's Molecular Genetics Department, who led the study together with research student Leehee Weinberger. PGCs arise within the early weeks of embryonic growth, as the embryonic stem cells in the fertilized egg begin to differentiate into the very basic cell types. Once these primordial cells become "specified," they continue developing toward precursor sperm cells or ova "pretty much on autopilot," says Hanna. The idea of creating these cells in the lab took off with the 2006 invention of induced pluripotent stem (iPS) cells - adult cells that are "reprogrammed" to look and act like embryonic stem cells, which can then differentiate into any cell type. Thus several years ago, when researchers in Japan created mouse iPS cells and then got them to differentiate into PGCs, scientists immediately set about trying to replicate the achievement in human cells. But until now, none had been successful.

Previous research in Hanna's lab pointed to new methods that could take human cells to the PGC state. That research had focused on the question of how human iPS cells and mouse embryonic cells differ: The mouse embryonic cells are easily kept in their stem cell state in the lab, while human iPS cells that have been reprogrammed - a technique that involves the insertion of four genes - have a strong drive to differentiate, and they often retain traces of "priming." Hanna and his group then created a method for tuning down the genetic pathway for differentiation, thus creating a new type of iPS cell that they dubbed "nave cells." These nave cells appeared to rejuvenate iPS cells one step further, closer to the original embryonic state from which they can truly differentiate into any cell type. Since these nave cells are more similar to their mouse counterparts, Hanna and his group thought they could be coaxed to differentiate into primordial germ cells.

Working with nave human embryonic stem and iPS cells, and applying the techniques that had been successful in the mouse cell experiments, the research team managed to produce cells that, in both cases, appeared to be identical to human PGCs. Together with the lab group of Prof. Azim Surani of Cambridge University, the scientists further tested and refined the method jointly in both labs. By adding a glowing red fluorescent marker to the genes for PGCs, they were able to gauge how many of the cells had been programmed. Their results showed that quite a high rate - up to 40% - had become PGCs; this quantity enables easy analysis.

Hanna points out that PGCs are only the first step in creating human sperm and ova. A number of hurdles remain before labs will be able to complete the chain of events that move an adult cell through the cycle of embryonic stem cell and around to sperm or ova. For one, at some point in the process, these cells must learn to perform the neat trick of dividing their DNA in half before they can become viable reproductive cells. Still, he is confident that those hurdles will one day be overcome, raising the possibility, for example, of enabling women who have undergone chemotherapy or premature menopause to conceive.

In the meantime, the study has already yielded some interesting results that may have significant implications for further research on PGCs and possibly other early embryonic cells. The team managed to trace part of the genetic chain of events that directs a stem cell to differentiate into a primordial germ cell, and they discovered a master gene, Sox17, that regulates the process in humans, but not in mice. Because this gene network is quite different from the one that had been identified in mice, the researchers suspect that more than a few surprises may await scientists who study the process in humans.

Hanna: "Having the ability to create human PGCs in the petri dish will enable us to investigate the process of differentiation on the molecular level. For example, we found that only 'fresh' nave cells can become PGCs; but after a week in conventional growth conditions they lose this capability once again. We want to know why this is. What is it about human stem cell states that makes them more or less competent? And what exactly drives the process of differentiation once a cell has been reprogrammed to its more nave state? It is the answers to these basic questions that will, ultimately, advance iPS cell technology to the point of medical use."

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Human primordial cells created in the lab

the senate finance comm opened hearings today national health care plan – Video


the senate finance comm opened hearings today national health care plan
"farmers insurance" "health insurance" "nationwide insurance" "auto insurance" "life insurance" "car insurance quotes" "insurance quotes" "insurance companies" "general insurance" "cheap auto...

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the senate finance comm opened hearings today national health care plan - Video

uaw president woodcock urges oreorganization of health care system – Video


uaw president woodcock urges oreorganization of health care system
"farmers insurance" "health insurance" "nationwide insurance" "auto insurance" "life insurance" "car insurance quotes" "insurance quotes" "insurance companies" "general insurance" "cheap auto...

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uaw president woodcock urges oreorganization of health care system - Video

Iowa minority access to health care tough

DES MOINES | Isaiah Newsome likes to play sports and hang out with friends like any 17-year-old. But most of the time those activities are cut short as his body, stricken with sickle cell anemia since birth, fills with pain.

It just randomly happens, said Newsome, of Des Moines. Theres no really preventing it or seeing it coming.

Getting insurance to cover his health care has never been easy, but at least he has had insurance the past year. Many low-income African-American families in Iowa do not.

A University of Iowa Public Policy Center study in December 2013 found African-American and Latino Iowans do not have the same access to health care as Asian and white Iowans. The report, which used data from a survey conducted in fall 2010 and spring 2011, also found African-Americans and Latinos are more likely to need medical care.

The disparities are a result of many factors, including a lower quality of care in general; higher-than-normal unmet need for care; poor diets; a higher likelihood to seek care from a hospital emergency room; and fewer safe and supportive neighborhoods.

Social aspects including poverty level, neighborhood, culture or race, account for 90 percent of what affects health status, the studys authors concluded.

The causes of health disparity vary, but we need to look beyond health care, said Dr. Peter Damiano, director of Iowa Public Policy Center and also its health policy research program. Iowa needs to be looking at behavior, genetics and environment.

Newsomes mother, Charice Williams, did not have health insurance for herself or her children until she signed up under the Affordable Care Act in 2013.

Even though I am low income, I am still over income for things. Everything goes by your gross income instead of what you really bring home as your net pay, said Williams, who works part-time for the city of Des Moines so that she can spend time caring for her son.

The study focused on the several factors that create a disparity in care, including overall health status, insurance coverage, need and access to care, lifestyle and family and social environment.

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Iowa minority access to health care tough

Health Care Sector Update for 12/24/2014: BCRX,ACHN,BLRX,NVS

Top Health Care Stocks

JNJ +0.82%

PFE +0.32%

ABT +0.23%

MRK +0.79%

AMGN +2.89%

Health care stocks were posting big rebounds Wednesday following yesterday's declines, with the NYSE Health Care Sector Index jumping nearly 0.8% and shares of health care companies in the S&P 500 up 1.2% as a group.

In company news, BioCryst Pharmaceuticals Inc. ( BCRX ) rose Wednesday after the company's BCX4161 experimental medication received orphan drug designation from U.S. regulators to prevent the rapid swelling of skin tissue in patients with hereditary angioedema.

BCX4161 works by selectively inhibiting plasma kallikrein and suppressing production of bradykinin, which is a peptide that causes blood vessels to dilate and smooth muscle to contract.

The U.S. Food and Drug Administration grants orphan drug status for drugs intended to treat diseases affecting fewer than 200,000 Americans. The designation provides federal grants, tax credits, fee waviers and other incentives to support development in addition to a seven-year exclusivity period to market the drug without competition.

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Health Care Sector Update for 12/24/2014: BCRX,ACHN,BLRX,NVS

Officials cite progress on health care enrollment

WASHINGTON (AP) The second sign-up season under President Barack Obama's health care law is off to a good start but has a way to go to make it a success, administration officials said Tuesday.

Health and Human Services Secretary Sylvia M. Burwell said 1.9 million new customers have picked a plan as of Dec. 19 through the federal insurance market that serves 37 states. Another 4.5 million have renewed existing coverage, with most automatically re-enrolled.

The numbers don't include states running their own insurance exchanges, including California and New York. The administration will release a full 50-state report next week, Burwell said.

"We still have a lot of work to do," she said. "But this is an encouraging start."

At her year-end news conference, Burwell dodged questions about a Supreme Court case seen as the most serious threat left to Obama's law. The case, King v. Burwell, will be argued in early March.

The health care law provides taxpayer-subsidized private insurance to people who don't have access to coverage through their jobs.

Plaintiffs in the Supreme Court case argue that the law, as written, only allows subsidies in states that have established their own insurance markets. Supporters of the law say that while the text may be confusing, Congress clearly intended to subsidize coverage in all 50 states.

Burwell wouldn't outline any contingency plans in the event the court rules against the administration.

"We believe that our position is the position that is correct and accurate," she said.

More than 8 in 10 customers in the insurance markets receive subsidies. Without them millions would be unable to afford their premiums. If the court's ruling goes against the administration, it's unclear if there would be a grace period while officials pursue a legislative fix or other solutions.

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Officials cite progress on health care enrollment

Health Care Briefs

By Staff Writer Bryan Construction to build new medical building

Bryan Construction won a $3.5 million contract to build the core and shell of a new 34,000-square-foot medical office building in southeastern Colorado Springs.

After tenant finishes, the two-story structure will ultimately house several medical tenants and specialties, including imaging, primary care, lab services, urgent care, physical therapy and orthopedics.

The Broadmoor Commons Medical Office Building will be built on Lake Plaza Drive, off the intersection of Lake Avenue and Venetucci Boulevard. Construction is expected to begin in January with completion in September, said Jennifer Taylor, manager of marketing and business development at Bryan Construction.

Weve successfully completed hundreds of thousands of square feet of medical space, said Doug Woody, executive manager for Bryan Construction. There should be little to no impact on the neighbors or traffic flow.

The contractor built the Harrison School District 2 Administration Building and is remodeling the interior of a medical building for the Kaiser Fountain Health Plan east of Memorial Park. It has finished projects at Fort Carson, Memorial Hospital, Penrad Imaging, Premiere Army Medical Clinic and more.

Marija B. Vader

The Tri-Lakes Health Pavilion in Monument will celebrate a community grand opening from 10 a.m.1 p.m. Saturday, Jan. 10, with building tours, health and fitness testing, demonstrations and family activities.

The residents of northern El Paso County may see a different way of health care delivery and fitness through a collaborative network of health, wellness and preventive services.

The new pavilion will integrate advanced, individualized exercise and fitness programs, pediatric medicine, adult primary care, family nutrition, orthopedic medicine, radiology, urgent care, occupational therapy and more, all in one location. The new 50,000-square-foot building, developed by a partnership of The YMCA of the Pikes Peak Region, Centura Health and the Wisconsin-based Boldt Company, is connected to the existing Tri-Lakes YMCA, located at 17230 Jackson Creek Parkway.

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Health Care Briefs

New health care strategy to introduce personalised medicine

Abu Dhabi: A comprehensive new health care strategy for the emirate of Abu Dhabi will focus on reducing critical gaps across medical specialities and improving access to health care, senior health officials announced in the capital on Wednesday.

One of the hallmarks of this plan, launched by the emirates health sector regulator, the Health Authority Abu Dhabi (Haad), is to reduce the prevalence of genetic diseases among residents. In addition, personalised medicine programmes will also be introduced to tailor management of diseases based on each individuals predisposition to health risks, Dr Maha Barakat, director-general at the Health Authority Abu Dhabi, told Gulf News.

Such personalised management of health is the future of medicine, and we are currently in the exploratory phase of implementing it. For example, a simple blood test can be used to extract the genetic profile of an individual, and based on inherent risks towards certain diseases, the individuals future treatment plans can be determined and precautionary measures taken, Dr Maha said.

She was speaking at a press conference held to launch the Haads health care plan for the next five years. The scheme highlights 58 initiatives distributed across seven priority areas, and was recently approved by the Abu Dhabi Executive Council.

While existing initiatives to improve patient satisfaction and to increase the reach of screening programmes have been revamped, new elements have also been introduced to address emerging health care concerns.

For example, the new plan aims to reduce the prevalence of genetic diseases, which were responsible for 2 per cent of all fatalities in 2013.

We understand that many of these congenital malformations and abnormalities occur due to consanguineous marriages. A standing premarital screening programme does address this concern, but we hope to create greater awareness among residents about these risks as well. In addition, we also hope to increase pre-gestational diagnoses and treatment of diseases to limit the number of children born with severe malformations, Dr Maha said.

There is still a shortfall in the provision of certain medical specialities in the emirate, including intensive medicine, neonatology, paediatrics, oncology, psychiatry, orthopaedics and rehabilitation. The Haad strategy aims to attract and retain specialists to fill these, especially Emirati professionals, said Dr Mugheer Al Khaili, the authoritys chairman.

Statistics released on Wednesday (December 24) show that about 4,800 more doctors and 13,000 nurses are required in Abu Dhabi by 2020, which translates into 1,700 additional doctors and 2,900 nurses annually.

In addition, officials are hoping to encourage further private sector investment into health care facilities.

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New health care strategy to introduce personalised medicine

"FREEDOM" Time-lapse of an Eagle Painting amazing art Cinnamon Cooney – Video


"FREEDOM" Time-lapse of an Eagle Painting amazing art Cinnamon Cooney
24x36 Acrylic on canvas original Available for sale by Cinnamon Cooney $864.00. - hartsherpa@gmail.com Speed paint time lapse of a original expressive eagle in explosive flight. - The large...

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"FREEDOM" Time-lapse of an Eagle Painting amazing art Cinnamon Cooney - Video