NASA Spends $392,000 on A Communications Book Should We Encounter Aliens

NASA Spends $392,000 on A Communications Book Should We Encounter Aliens In his latest report on government waste, outgoing Sen. Tom Coburn found that the federal government spent an eye-popping $50 million on paid administration leave. Worse, about 40% of the money went to workers who had, shall we say, behavioral problems at work.

Government employees who were caught doing things such as charging booze on government credit cards, surfing porn on government computers and sexually harassing co-workers were often punished by getting paid not to show up to worksometimes for years.

Some of Coburns examples make you wonder what it takes to get fired from a government post. The IRS Lois Lerner, for example, pocketed $50,000 in paid leave after her role in targeting conservative groups was exposed. The head of Iran operations for the CIA was put on paid leave after creating a work environment so hostile, it put that division in disarray. So was a Secret Service agent found passed out in a hallway from a previous nights boozing while on presidential security detail.

Coburn also found incredible examples of waste at agencies that constantly claim poverty. A prime example is the National Institutes of Health, which in the wake of the Ebola outbreak said it could have developed a vaccine by now if it werent for budget cuts. The same NIH had $2 billion to blow on Swedish massages for rabbits, studying whether moms love their dogs or their children more, researching writing on Buddhist meditation, and developing a mobile app designed to help parents get their children to eat vegetables.

NASA, which currently cant launch a man into space on its own, blew $350 million on a launch tower for a canceled rocket system, wastes $43 million maintaining other facilities that serve no purpose, and spent $392,000 on a book offering communication advice should we encounter aliens.

The government doesnt need more money to do its job. It needs a major housecleaning.

Investors Business Daily

IRS Violates Federal Law for More Than A Decade Under the IRS Restructuring and Reform Act of 1998, the agency is required to provide annual recommendations for reducing the complexity of the administration of Federal tax laws; and for repeal or modification of any provision the Commissioner believes adds undue and unnecessary complexity to the administration of the Federal tax laws. But as noted by the National Taxpayer Advocate, the agency has not bothered to produce such a report since 2002. Only two such reports have ever been issued, in 2000 and 2002.

Each year Americans spend six billion hours complying with the four million word Internal Revenue Code. But the IRS apparently cant be bothered to compile the report. When asked by the NTA to explain themselves, the IRS said it would require about two full time employees working for about a year to produce the report.

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NASA Spends $392,000 on A Communications Book Should We Encounter Aliens

Science Documentary:Future Scenarios, Nanotechnology, Carbon Nanotubes, Nanomagnetism – Video


Science Documentary:Future Scenarios, Nanotechnology, Carbon Nanotubes, Nanomagnetism
Science Documentary:Future Scenarios, Nanotechnology, Carbon Nanotubes, Nanomagnetism As technology progresses into the future, it can bear several very diff...

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Nature Nanotechnology : Macroscopic contraction of a gel induced by the integrated motion… – Video


Nature Nanotechnology : Macroscopic contraction of a gel induced by the integrated motion...
Macroscopic contraction of a gel induced by the integrated motion of light-driven molecular motors. Quan Li et al. (2015), Nature Nanotechnology, http://dx.doi.org/10.1038/nnano.2014.315 Making...

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Use of nanotechnology in cosmetics and pharmaceuticals

9 hours ago Professor Dr Mahiran Basri. Credit: Universiti Putra Malaysia

The use of oils and fats has been successfully diversified, resulting in an innovation formulated through nanotechnology that is beneficial to pharmaceutical and cosmetics industries.

A Faculty of Science, Universiti Putra Malaysia (UPM) lecturer, Professor Dr Mahiran Basri, not only succeeded in producing new useful substances made of oils and fats for the industry, but also managed to produce them through environmental-friendly ways.

"This organic synthesis uses enzymes and it is produced through nanotechnology. Our focus is to process new substances derived from oils and fats," she said in an interview at her office.

In the field of cosmetics, for instance, she said there are antioxidants and anti-aging substances, through the use of nanotechnology, those substances can easily absorb through the skin.

This way, they would be more effective, she added.

"What is also important is that the materials are clean and safe," said the winner of the Islamic Educational Scientific and Cultural Organization (ISESCO) for Science and Technology 2014 award, which was held in Rabat, Morocco, in December.

The recognition was based on her active research and excellent performance in the field of chemistry including her far-reaching oil palm research that has contributed to the pharmaceutical and cosmetics industries.

The award was presented by the ISESCO Director General, Dr Abdulaziz Othman Altwaijri as Prof Mahiran took home a certificate, a medal and a cash prize of USD$5,000.

The biennial award has been organised by the Organisation of the Islamic Conference (OIC) since 1979 to foster and strengthen collaboration in the fields of science, education and culture among the OIC members.

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VCU researcher receives NSF grant to extend lifespan of Li-ion batteries

IMAGE:Arunkumar Subramanian, Ph.D., works with the nanobot, a co-integrated device created on silicon chips, which includes a lithium cell and a nanoelectromechanical resonator for charge capacity measurements. view more

Credit: Kate Vinnedge, School of Engineering

A Virginia Commonwealth University professor has received a five-year, $505,000 award from the National Science Foundation to make lithium-ion batteries -- which power electric vehicles and portable electronic devices -- far more efficient, sustainable and environmentally friendly.

Arunkumar Subramanian, Ph.D., an assistant professor in the Department of Mechanical and Nuclear Engineering in the School of Engineering, will use the grant to deliver technological advances that reduce the cost and carbon footprint of Li-ion batteries by extending their lifespan. He will simultaneously research alternative battery materials that are both nontoxic and more abundant.

"If you look at electrical energy storage solutions that are used in today's electric vehicles and portable electronic devices, you would find that lithium-ion batteries is the technology of choice," Subramanian said. "But if you want to make this technology truly sustainable and environmentally benign, then we need to be able to reduce its cost, as well as its carbon footprint as compared to energy derived from other sources such as fossil fuels."

Subramanian plans to address these goals by extending the lifespan of Li-ion batteries made from sustainable electrode materials, which are derived from the nontoxic manganese oxide material system.

"This project is likely to result in transformative innovations for the battery industry, which in turn will impact a whole host of consumer devices and cars," said Ram Gupta, Ph.D., a professor and associate dean for research in the School of Engineering.

An overarching goal of the project, "Sustainable Solutions for Li-ion Batteries through Cycle-Life Improvements in Nanostructured, 'Green' Cathodes," is to maximize the environmental benefits of electric cars.

"Electric vehicles are one alternative for reducing fossil fuel consumption and greenhouse gas production for sustainable transportation needs," according to the project's abstract. "Electric vehicles require rechargeable batteries that balance the electrical energy storage and power delivery needs, and these batteries must have a lifespan sufficient to reduce cost and achieve true carbon footprint reduction. Furthermore, batteries should be manufactured from sustainable materials to minimize environmental impact."

The award is from National Science Foundation's Faculty Early Career Development (CAREER) Program, which provides the foundation's most prestigious awards in support of junior faculty who exemplify the role of teacher-scholars through outstanding research, excellent education and the integration of education and research within the context of the mission of their organizations.

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VCU researcher receives NSF grant to extend lifespan of Li-ion batteries

Obituary: Troy Yandell

The Courier Your Messenger For The River Valley

Troy was born April 11, 1919, to the late James Walter Bud and Mahalia Mattie Weaver Yandell at the county line of Logan and Yell Counties just south of Blue Mountain.

He was a United States Navy veteran of World War II, retired cattle and cotton farmer and a devoted Christian and Bible student.

Troy was preceded in death by his parents; his first wife, Ina Pearl Clack Yandell; two brothers, Wilburn Yandell and Willard Yandell; and two sisters, Lillian Yandell and Myrtle Yandell.

Troy is survived by his wife of 57 years, Lillie Ina Belle Garner Yandell of Havana; a son and daughter-in-law, Charles and Fern Yandell of Havana; one brother, Roy D. Yandell of Boise, Idaho; one granddaughter and her husband, Allison and Kenny Akin; three great-grandchildren, Megan Pearce and her fiance Richard Conrad, Ryan Akin and Haley Akin; and a host of nieces, nephews and friends.

Funeral service will begin at 10 a.m. Thursday, Jan. 22, 2015, at the Moores Chapel Church. Burial will be at Moores Chapel Cemetery with Military Honors.

Visitation will be 5-7 p.m. today at the funeral home.

Pallbearers include Lonnie Kennedy, Johnny Kennedy, Eston Yandell, Greg Caldwell, Danny Rohde and Jared Brasher.

Arrangements by Cornwell Funeral Home of Danville.

Online guestbook and condolences at http://www.cornwellfuneralhomes.com.

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Mutated ATRX Gene Linked to Brain and Pancreatic Neuroendocrine Tumors is Potential Biomarker for Rare Adrenal Tumors …

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Newswise PHILADELPHIAA somatic mutation in the ATRX gene has recently been shown as a potential molecular marker for aggressive brain tumors, such as gliomas, neuroblastomas and pancreatic neuroendocrine tumors. Now, for the first time, researchers at at the Perelman School of Medicine at the University of Pennsylvania have found that the same mutated gene may serve as a much-needed biomarker for the pheochromocytomas and paragangliomas (PCC/PGL) that become malignant. These rare neuroendocrine tumors are typically benign, but when they go rogue, they become very aggressive.

The study was published online ahead of print today in Nature Communications.

Several inherited mutated genes, such as VHL and RET, have been found to be associated with PCC/PGL; however, little is known about the somatic genetic changes leading to tumorigenesis in these patients.

This is the first step towards a better understanding of this type of disease, and to try to identify better biomarkers of poor outcomes, said senior author Katherine Nathanson, MD, an associate professor in the division of Translational Medicine and Chief Oncogenomics Physician for the Abramson Cancer Center. The mutation could not only serve as that biomarker for metastatic disease, but also a potential therapeutic drug target in the future.

PGLs are rare tumors of nerve ganglia in the body, whereas PCCs form in the center of the adrenal gland, which is responsible for producing adrenaline. The tumor causes the glands to overproduce adrenaline, leading to elevated blood pressure, severe headaches, and heart palpitations. Both are found in about two out of every million people each year. An even smaller percentage of those tumors become malignant. For that group, the five-year survival rate is about 50 percent.

No reliable predictors of aggressive disease exist other than an inherited mutation in the SDH gene, but only half of patients who develop metastatic disease carry that mutation, meaning the other half have no known predictors.

About 60 percent of PCC/PGLs are sporadic, while the remaining 40 percent are hereditary. Most recurrent somatic mutations are observed almost exclusively in sporadic PCC/PGLs.

Researchers, including Lauren Fishbein, MD, PhD, MTR, an instructor in the division of Endocrinology, Diabetes and Metabolism at the Perelman School of Medicine, investigated the mutations using whole exome sequencing on a set of 21 tumor/matched germline DNA samples of either sporadic or inherited PCC/PGL. The idea was to compare benign tumors to clinically aggressive ones in order to spot markers of malignant potential.

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CAP Partners to Launch Crowd-Sourced Molecular Oncology Tumor Board Series

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Newswise NORTHFIELD, ILL. The College of American Pathologists (CAP), the American Society of Clinical Oncologys (ASCO) ASCO University, and the Association for Molecular Pathology (AMP) recently announced their partnership in the creation of the Molecular Oncology Tumor Board series, an online and user-driven resource designed to help cancer care providers with the interpretation and understanding of tumor molecular profiling tests and studies.

The new crowd-sourced series allows for maximum user input and interaction, and encourages a multidisciplinary discussion of this rapidly growing area of cancer care. Access to the Molecular Oncology Tumor Boards is now available for free through the ASCO Connection website, ASCOConnection.org.

A healthy flow of information between oncologists and pathologists is critical to meeting each cancer patients unique goals and needs during treatment, said CAP President Gene N. Herbek, MD, FCAP. The Molecular Oncology Tumor Board series offers an education opportunity for pathologists and oncologists to share the latest information and best practices in genomic medicine in a convenient, real-time format.

Each month the Molecular Oncology Tumor Boards will feature a case-based discussion involving genetic or genomics in the treatment of cancer. The open forum will allow participants to post questions or comments about the cases, engage in discussion, and compare approaches.

Understanding the results of tumor molecular profiling studies is challenging, and the field of cancer genomics is rapidly changing with new information being generated at a dizzying pace, said ASCO Chief Medical Officer Richard L. Schilsky, MD, FACP, FASCO. All oncologists struggle to keep abreast of this information and to learn how to use tumor molecular profiling to deliver high-quality, personalized cancer care. We hope that this new educational program will foster learning about tumor molecular genomics in an engaging and interactive format fueled by real-world case studies.

Two rotating faculty members, a pathologist and medical oncologist, will lead the case discussion each month, provide input, and after two weeks of discussion, will post a summary of the case discussion that addresses actionable aberrations identified and treatment options available based on clinical parameters. The information provided in the case discussions are designed to be educational and are not intended to make treatment recommendations.

The Molecular Oncology Tumor Boards is available to anyone who creates an ASCO.org account and logs into ASCOConnection.org. Participants who complete and pass a short post-test can also earn Continuing Medical Education credit.

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Case Western Reserve Scientists Identify Proteins Likely to Trigger Psoriasis

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Newswise Case Western Reserve scientists have taken a huge leap toward identifying root causes of psoriasis, an inflammatory skin condition affecting 125 million people around the world. Of the roughly 50,000 proteins in the human body, researchers have zeroed in on four that appear most likely to contribute this chronic disease. The findings, published this month in Molecular & Cellular Proteomics, dramatically advance efforts to understand how psoriasis develops and, in turn, how to stop it.

Psoriasis affects 2 to 3 percent of the population worldwide, said senior author Nicole L. Ward, PhD, associate professor of dermatology and neurosciences, Case Western Reserve University School of Medicine. The underlying cause of psoriasis remains unknown, and the specific signals that trigger disease onset are still being investigated. There currently is no cure.

Wards lab is focused on studying the pathogenesis of the disease and its co-morbidities, including heart attack and stroke. Her group is actively working to identify new molecules key to the disease process that could become potential drug targets. Ward has a personal interest in this research her father suffers from psoriasis.

Psoriasis is an autoimmune skin disease characterized by well-demarcated areas of red, raised and scaly skin next to areas of normal-appearing skin. Autoimmune diseases are those where the body launches an abnormal immune response against its own tissues. Another complication of psoriasis is joint involvement, a condition termed psoriatic arthritis.

Ward and her team first narrowed their pool of potential culprits to about 1,280 proteins that are differentially regulated in the condition. From there, they focused on five that stood out either because of their high prevalence in human psoriasis or their prominence in other studies relating to human psoriasis tissue. Wards lab team took skin tissue samples from her well-established psoriasis transgenic mouse model, called the KC-Tie2 mouse, and compared it to skin tissue samples of normal mice. Her lab collaborated with Mark R. Chance, PhD, director of the Center for Proteomics and Bioinformatics, CWRU School of Medicine, and his team at the center to identify new proteins that were differentially regulated in the skin tissue of psoriasis mice compared to the skin tissue of healthy mice.

To ensure that the proteins identified in the mouse were important to human psoriasis, her team then examined human psoriasis skin cells, known as keratinocytes, and human psoriasis skin tissue samples to confirm the increased presence of these proteins in human disease. In the skin of the psoriasis mice, investigators first identified increases in stefin A1 (342.4-fold increased; called cystatin A in humans); slc25a5 (46.2-fold increased); serpinb3b (35.6-fold increased; called serpinB1 in humans) and KLK6 (4.7-fold increased). The team found no increases of the Rab18 protein in skin tissue of the mice, and so ruled it out as a psoriasis-generating culprit. Investigators then confirmed the increased presence of the Serpinb3b, KLK6, Stefin A1 and Slc25a5 proteins in human lesional psoriasis skin tissue, and human lesional psoriasis skin cells compared to healthy control skin tissue and skin cells.

We were interested in looking for the increased presence of these proteins, not just in the psoriasis-like skin inflammation of the mouse, but more importantly, we needed to know how the increased presence of these proteins translated to human psoriasis, Ward said. So we took the information we discovered in the mouse model and went back to the patients and confirmed the increase in these proteins in their lesional psoriasis skin tissue. We are really focused on, and enthusiastic about, our ability to perform successfully translational bench-to bedside-and-back-again psoriasis research here at CWRU School of Medicine Department of Dermatology and the Murdough Family Center for Psoriasis at University Hospitals Case Medical Center. Its what we excel at and what we love to do.

The next step in pursuing this line of research for Wards team will be uncovering the role and significance of each of these proteins in the progression of psoriasis. Determining the individual contributions of each protein will help provide strategic therapeutic targets to change the course of a patients psoriasis or, at the very least, provide a better understanding of how a change in the regulation of these proteins contributes to skin inflammation and psoriatic disease.

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Millennial Mind Upload | Online snapshot thoughts, ideas …

As long as you unlock the beast it does not matter

Unsleashed my glow will slay you,

Grey and dark,

My light reflects

Forever!

After the burn out epidemy there is another plague we humas indulge into: the chronical, multifactorial, incurable mobbing syndrome. The mobbed individuals see themselves as victims but they are only higher evolved humas. Innate superiormorality served by an overdose of emotional intelligence triggers feelings of danger in the mobber. Threat reactions allows mobbers to find the Achiles heel of the mobbed one: empathy. Can empathy be turned off? Can we train this on/off switch?

A lot has been written on negative effects of mobbing. Are there any positive ones? NO! Can we shift the negative into constructive? YES: through creation! By artistical expression and/or creativity we are offered not onlythe possibility to let it out but also we are empowered by the fulfillment of the result and so are offered theoption of letting go, neutralizing rage. Remember that negative feelings activate our creativepotential also and using this can be trained.

The lines aboveinspired by mobbing for all the beasts of creativity, all empathy addicts:a single ray of light slays an ocean of darkness. You are the light!

Supposing you are one of those who afford at least the following: a house, food, a computer and internet access Ive got a trick for you to get really rich.

Before describing my idea here as being crap just let me define one thing:

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Millennial Mind Upload | Online snapshot thoughts, ideas ...

Rage | Millennial Mind Upload

As long as you unlock the beast it does not matter

Unsleashed my glow will slay you,

Grey and dark,

My light reflects

Forever!

After the burn out epidemy there is another plague we humas indulge into: the chronical, multifactorial, incurable mobbing syndrome. The mobbed individuals see themselves as victims but they are only higher evolved humas. Innate superiormorality served by an overdose of emotional intelligence triggers feelings of danger in the mobber. Threat reactions allows mobbers to find the Achiles heel of the mobbed one: empathy. Can empathy be turned off? Can we train this on/off switch?

A lot has been written on negative effects of mobbing. Are there any positive ones? NO! Can we shift the negative into constructive? YES: through creation! By artistical expression and/or creativity we are offered not onlythe possibility to let it out but also we are empowered by the fulfillment of the result and so are offered theoption of letting go, neutralizing rage. Remember that negative feelings activate our creativepotential also and using this can be trained.

The lines aboveinspired by mobbing for all the beasts of creativity, all empathy addicts:a single ray of light slays an ocean of darkness. You are the light!

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Rage | Millennial Mind Upload

Download of the day: Cloudfogger

It's a good idea to keep your cloud data securely encrypted to protect it from prying eyes, and Cloudfogger provides a free solution that does exactly that with minimal hassle.

2014 had its fair share of hacking scandals, and even everyday Joes couldn't feel completely confident that they wouldn't end up with their data scattered around the internet. Given how popular cloud storage has become and how ready we are to upload our documents to be stored on some remote server adding an extra layer of encryption can be a very good idea indeed.

That's why you should give Cloudfogger a try. Protects your files with a hefty chunk of 256-bit AES (Advanced Encryption Standard) encryption which complements your cloud host's own encryption making it even harder for hackers to get their grubby mitts on your precious data. It does it seamlessly, too, so there's no need to remember to protect your files before uploading them; Cloudfogger does it all for you.

You can store the encryption key locally, ensuring it's not stored online and therefore won't be handed over if anyone asks for it. In light of the NSA surveillance scandal, that's more peace of mind that your data is safely protected from prying eyes.

And to round it all off, Cloudfogger is completely free, so you don't even have to shell out to keep your files securely encrypted.

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Personalized Medicine- Dr Raj Kumar, Director, AIIMS Rishikesh part 2 – Video


Personalized Medicine- Dr Raj Kumar, Director, AIIMS Rishikesh part 2
Dr Raj Kumar presented the experience of AIIMS Rishikesh and highlighted ups and downs in growth of Institute at the 54th Annual Conference of National Academy of Medical Sciences (India) was...

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OMICS International | 1000+Global Events on Pharma, Medicine, Science and Technology – Video


OMICS International | 1000+Global Events on Pharma, Medicine, Science and Technology
OMICS International is an online open access publisher and a scientific event organizer publishes around 500 peer-reviewed scholarly Open access journals and organizes 300+ international ...

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OMICS International | 1000+Global Events on Pharma, Medicine, Science and Technology - Video