Waking up to Sleep 2015 University of Exeter Medical School CPD event – Video


Waking up to Sleep 2015 University of Exeter Medical School CPD event
To find out more or to book a place visit the University of Exeter online store - http://store.exeter.ac.uk/browse/extra_info.asp?compid=1 modid=2 catid=47 prodid=963.

By: University of Exeter

Read the original post:

Waking up to Sleep 2015 University of Exeter Medical School CPD event - Video

Stanley Aronson, Brown medical school founder, Providence Journal columnist, dies

Stanley M. Aronson, the founding dean of Brown Universitys medical school and a weekly contributor to The Providence Journals Monday commentary page, has died at 92.

Aronson died Wednesday morning at the Philip Hulitar Inpatient Center, which is run by Home and Hospice Care of Rhode island. Aronson was a founder of the organization and served on its board.

In 2014, Aronson was honored by Brownwith a $3 million research fund named in his honor.The fund is used to support innovative investments in medical education and research.

Dr. Aronson is an adored giant of in the worlds of medicine and medical education and also in the life of Brown and Rhode Island, Chancellor Thomas J. Tisch said at the time of the funds establishment.

Aronsons column typically dealt with history and medicine. His first column ran in December of 1992. On the occasion of his 1,000th essay in January of 2011, he joked that he had clung to this Monday morning site, much like herpes tenacious but only rarely fatal.

Arthur Robbins, a friend of Aronson and a member of the Butler Hospital Foundation, wrote the following about Aronson in the Providence Journal in 2013:

I could go on at length about Dr. Aronsons achievements as a pioneering neurologist, teacher and clinician, as the founding dean of the Alpert School of Medicine, eradicating Tay Sachs, to be the first to identify Lewy Body Dementia, just to name a few. But, suffice it to say, Stan has dedicated his career to championing those suffering from the most debilitating neurological disorders and mentoring generations of physicians.

On Twitter: @RichSalit

The rest is here:

Stanley Aronson, Brown medical school founder, Providence Journal columnist, dies

Arizona could write off more medical school debt

PHOENIX State lawmakers are moving to get more doctors into rural and medically underserved areas of the state.

A Senate panel voted Tuesday to expand an existing program that helps doctors repay their medical school debts if they agree to go where they are needed. SB 1194, proposed by Sen. Gail Griffin, R-Hereford, now goes to the full Senate.

Rep. Heather Carter, R-Cave Creek, introduced similar legislation in the House. That measure, HB 2495, is awaiting a hearing.

The states challenged finances should not impede final approval because the expansion is structured so it would not require any additional state dollars.

Kristen Boilini, lobbyist for the Arizona Alliance for Community Health Centers, said the change permits the program to take private donations, which she said will be offered.

She said Arizona needs another 442 full-time primary care physicians, 441 dentists and 204 behavioral-health providers and psychiatrists.

That includes not just in rural areas. She said while physicians are attracted to some urban areas, there are inner-city areas in both Pima and Maricopa counties where the number of medical providers falls short.

Generally, theyre communities with high uninsured, underinsured folks, Boilini said, with a high percentage of residents getting their coverage through the Arizona Health Care Cost Containment System, the states Medicaid program. And that presents a problem of its own.

AHCCCS provider payment rates are so low, you dont get a lot of private practice groups that want to go work in those areas, she said. That makes these communities dependent on nonprofit groups and community health centers.

But even they have a hard time attracting physicians because they dont pay what a private practice in north Scottsdale is going to pay, Boilini said.

Originally posted here:

Arizona could write off more medical school debt

Mom, 56, dies week after birthing twins she longed for

By Newser Editors

Newser

In her 56 years, Lisa Swinton McLaughlin racked up more accomplishments than most who live decades longer manage to do: A Creighton University law school grad, she worked for 13 years as a Nebraska special assistant attorney generalbefore heading to medical school and ultimately becoming executive medical officer with the American Red Cross in Baltimore.

As a 2009 press release explained, McLaughlin "specialized in child abuse and neglect cases. Her exposure to the medical issues of these children led her to apply to medical school." But there remained one void: children of her own.

McLaughlin married husband Mike in 1999, and spent a decade undergoing various fertility and in-vitro procedures. And then, last year, she became pregnant with twins. She gave birth to premature boys, both healthy, on Dec. 27, reports the Omaha World-Herald.

Sons Jordan, 3 pounds and 3 ounces, and Dylan, 3 pounds, remained in the hospital when McLaughlin headed home four days later. Mike says she was in pain but attributed it to the cesarean section incision.

Though she was able to hold the babies and "stroke them and love them," McLaughlin died of a bowel obstruction on Jan. 4. Death "wasn't even in her vocabulary," Mike tells the World-Herald.

The 67-year-old plans to move back to his native Nebraska so that family members can help him raise the boys. (A Phoenix woman died before she could hold her newborn quadruplets.)

This article originally appeared on Newser: Woman, 56, Dies Week After Having Longed-For Twins

More From Newser

View post:

Mom, 56, dies week after birthing twins she longed for

Scott Walker Steps Out

Jan 28, 2015 8:28am

By MICHAEL FALCONE (@michaelpfalcone)

NOTABLES

THE ROUNDTABLE

ABCs RICK KLEIN: Indiana Gov. Mike Pence drew headlines this week for his odd if not just plain ill-conceived state news service, sparking enough Pravda and Kim Jong Un Tweets to power a Seth Rogen movie. But the most consequential thing Pence may have done this week, at least when it comes to 2016, is the deal he cut to expand Medicaid using funds available under Obamacare. If Pence winds up running, his move will become a major point of contention; if he doesnt, hes given some other key candidates a strong talking point, maybe even precious cover. This is shaping up as one of the biggest fault lines inside the Republican presidential race. Possible candidates will run the range of outright rejection of Obamacare funds (Jindal, Perry), through special state-specific deals for some expansion (Walker, and now Pence), right up to accepting the money and the coverage expansion that was designed as a key piece of President Obamas healthcare overhaul (Christie, Kasich). And, of course, well have the senators in the field, who can and almost surely will take the clean stance that any acceptance of Obamacare funds is abetting a fatally flawed program.

ABCs SHUSHANNAH WALSHE: Scott Walkers launch of his Our American Revival political committee Tuesday could not have happened at a better time, fresh off his well-received speech last weekend at the Iowa Freedom Summit. Whether the roll-out was long planned or not, using the momentum from his star turn is a perfect way to keep the 2016 story on him over his potential opponents. Its a 527 not a leadership PAC, like possible rivals Jeb Bush and Chris Christie have recently set up, but he will still be able to use the funds to travel to early states or donor meetings. And speaking of donors, like a PAC, it gives a spot for early supporters to place funds ahead of a full-fledged campaign.

ON THE ROAD WITH POTUS

FIRST LADYS VISIT TO SAUDI ARABIA SENDS STRONG MESSAGE ABOUT WOMEN. In a country where women have few rights, First Lady Michelle Obama yesterday seemed to lead by example. There she was, standing side-by-side with her husband as he stepped off Air Force One in Riyadh Tuesday, where, during a brief visit, the president offered condolences for the recent death of King Abdullah and met with his successor, King Salman. According to ABCs MARY BRUCE, the first lady accompanied the president throughout the stay, embodying some of the reforms that her husband is pushing the country to adopt. Wearing pants and her head uncovered, Mrs. Obama stood dutifully beside her husband as he shook hands with the Saudi delegation on the airport tarmac Tuesday morning and again at Erga Palace on the outskirts of Riyadh. Due to the cultural constraints, the first lady purposely stood slightly behind her husband and waited for a gesture to be made to her by the men in the receiving line. If one of the men initiated a handshake she returned, if not then she simply smiled or nodded politely. http://abcn.ws/1JC1iqO

See the article here:

Scott Walker Steps Out

Greek Syriza & MMT Win – Peter Schiff, Austrian, Libertarian Economics Lose Big. – Video


Greek Syriza MMT Win - Peter Schiff, Austrian, Libertarian Economics Lose Big.
Peter Schiff has never been or ever will be an economist. Every single prediction, claim, statement has been a complete failure year after year after year. Which is why he lost 60% of his clients...

By: Minethis1

Read the original post:

Greek Syriza & MMT Win - Peter Schiff, Austrian, Libertarian Economics Lose Big. - Video

Former Kansas Libertarian lieutenant governor candidate says he can save KanCare money

KANSAS CITY, KAN. ---- Wichita physician and former lieutenant governor candidate Josh Umbehr is scheduled to talk to a legislative committee Wednesday about integrating direct primary care into KanCare.

Josh Umbehr, who runs a direct primary care practice called Atlas MD, gleaned 4 percent of the vote in November while running on the Libertarian ticket with his father, Alma attorney Keen Umbehr.

Josh Umbehr used the campaign in part to tout the benefits of the direct primary care model in which family physicians avoid the complexities of fee-for-service insurance reimbursement by charging their patients an all-inclusive monthly membership fee instead.

He is set to speak to the Vision 2020 Committee, which has scheduled hearings on Medicaid reform. Josh Umbehr and his father also have been trying to connect with members of Gov. Sam Brownbacks administration to talk about incorporating the direct primary care model into KanCare, the states $3 billion privatized Medicaid program.

We have had limited talks about KanCare but would like to explore it further and talk with Lt. Gov. (Jeff Colyer) about it in more detail, Josh Umbehr said.

Keen Umbehr said recently that he and his son already met with former Brownback administration official Steve Anderson to discuss their idea.

Anderson, Brownbacks former budget director, is now an analyst for the Kansas Policy Institute, a conservative think tank. Keen Umbehr said Anderson suggested he and his son propose a pilot project with 1,000 Wichita-area Medicaid recipients.

Anderson also said he would contact Colyer, who has been the governors point man on KanCare, about the idea.

Eileen Hawley, a spokeswoman for Brownback, said she is unaware of any dialogue between Mr. Umbehr and the Administration.

Hawley said primary care under KanCare already is working well and keeping more Medicaid patients out of emergency rooms. According to the Direct Primary Care Coalition, other states have worked direct primary care practices into their Medicaid systems. They include Washington state.

Continue reading here:

Former Kansas Libertarian lieutenant governor candidate says he can save KanCare money

Wellcome Trust builds 1,728-core grid for DNA analysis

The Wellcome Trust Centre has deployed a high-performance computing cluster based on Fujitsu blades, Mellanox InfiniBand and DataDirect Networks storage systems to support statistical genetics research.

Designed in conjunction with OCF, a provider of high-performance computing (HPC), data management, big data storage and analytics, the cluster enables researchers to run statistical analysis on the human genome.

The hardware powers applications that analyse small genetic differences across a population of 1,000 people.

Fujitsu BX900 blade with Intel Ivy Bridge CPUs are used in the cluster, giving performance 2.6 times better than its predecessor, built in 2011.

It boasts 1,728 cores of processing power, up from the 912 of its forerunner, with 16GB of 1866MHz memory per core compared with a maximum of 8GB per core on the older cluster of the Wellcome Trust Centre for Human Genetics (WTCHG).

Robert Esnouf, head of the research computing core at WTCHG, said: If you are interested in a certain disease, you can partition the genome and analyse the genetic difference between those individuals who have a medical condition like diabetes and those that do not.

Processing power limits the number of people whose DNA makeup can be analysed statistically. But the more DNA that is analysed, the greater the accuracy of the statistical analysis.

Typically, a single human genome requires 30TB. Esnouf said that processing the DNA data of a thousand individuals requires a lot of I/O remapping.

He added: An individual may have thousands of different genetic variations. The more people you can get, the more chance you have of finding low-frequency genetic differences.

The new cluster works alongside a second production cluster; both clusters share a Mellanox FDR InfiniBand network that links the compute nodes to a DDN GridScaler SFA12K storage system whose controllers can read block data at 20Gbps. According to WTCHG this speed is essential for keeping the cluster at maximum utilisation and consistently fed with genomic data.

Go here to read the rest:

Wellcome Trust builds 1,728-core grid for DNA analysis

Researchers pinpoint two genes that trigger severest form of ovarian cancer

In the battle against ovarian cancer, UNC School of Medicine researchers have created the first mouse model of the worst form of the disease and found a potential route to better treatments and much-needed diagnostic screens.

Led by Terry Magnuson, PhD, the Sarah Graham Kenan Professor and chair of the department of genetics, a team of UNC genetics researchers discovered how two genes interact to trigger cancer and then spur on its development.

"It's an extremely aggressive model of the disease, which is how this form of ovarian cancer presents in women," said Magnuson, who is also a member of the UNC Lineberger Comprehensive Cancer Center. Not all mouse models of human diseases provide accurate depictions of the human condition. Magnuson's mouse model, though, is based on genetic mutations found in human cancer samples.

Mutations in two genes -ARID1A and PIK3CA -- were previously unknown to cause cancer. "When ARID1A is less active than normal and PIK3CA is overactive," Magnuson said, "the result is ovarian clear cell carcinoma 100 percent of the time in our model."

The research also showed that a drug called BKM120, which suppresses PI3 kinases, directly inhibited tumor growth and significantly prolonged the lives of mice. The drug is currently being tested in human clinical trials for other forms of cancer.

The work, published in the journal Nature Communications, was spearheaded by Ron Chandler, PhD, a postdoctoral fellow in Magnuson's lab. Chandler had been studying the ARID1A gene -- which normally functions as a tumor suppressor in people -- when results from cancer genome sequencing projects showed that the ARID1A gene was highly mutated in several types of tumors, including ovarian clear cell carcinoma. Chandler began researching the gene's precise function in that disease and found that deleting it in mice did not cause tumor formation or tumor growth.

"We found that the mice needed an additional mutation in the PIK3CA gene, which acts like a catalyst of a cellular pathway important for cell growth," Chandler said. Proper cell cycle regulation is crucial for normal cell growth. When it goes awry, cells can turn cancerous.

"Our research shows why we see mutations of both ARID1A and PIK3CA in various cancers, such as endometrial and gastric cancers," Chandler said. "Too little expression of ARID1A and too much expression of PIK3CA is the perfect storm; the mice always get ovarian clear cell carcinoma. This pair of genes is really important for tumorigenesis."

Magnuson's team also found that ARID1A and PIC3CA mutations led to the overproduction of Interleukin-6, or IL-6, which is a cytokine -- a kind of protein crucial for cell signaling that triggers inflammation. "We don't know if inflammation causes ovarian clear cell carcinoma, but we do know it's important for tumor cell growth," Chandler said.

Magnuson added, "We think that IL-6 contributes to ovarian clear cell carcinoma and could lead to death. You really don't want this cytokine circulating in your body."

Read the original post:

Researchers pinpoint two genes that trigger severest form of ovarian cancer

HCA 322 Week 1 DQ 2 Autonomy, Fidelity, and Confidentiality – Video


HCA 322 Week 1 DQ 2 Autonomy, Fidelity, and Confidentiality
http://www.fres-courses.com/product/hca-322-week-1-dq-2-autonomy-fidelity-and-confidentiality HCA 322 Week 1 DQ 2 Autonomy, Fidelity, and Confidentiality Autonomy, Fidelity, and Confidentiality....

By: Glenda Marck Marck

See the original post here:

HCA 322 Week 1 DQ 2 Autonomy, Fidelity, and Confidentiality - Video