Supreme sash to Liberty bull

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Commonwealth Bank regional manager Corey Penn, cattle judges Anthony Hurst and Peter Falls, Elders senior livestock auctioneer Don Morgan, and Kevin and Robin Yost from Liberty Charolais with Liberty Just Ramblin Along, the 1074kg supreme exhibit.

Toodyay stud Liberty Charolais has won the supreme cattle exhibit ribbon at Wagin Woolorama for its 1074kg Charolais bull.

A month shy of turning two, Liberty Just Ramblin Along impressed Eastern States judges Anthony Hurst and Peter Falls, who were unanimous in their decision.

The multibreed champion bull, earlier judged champion and grand champion Charolais, was chosen as the supreme over the champion female Charolais and multibreed champion female entry, Quicksilver Fashion F35.

Liberty Charolais stud principal Kevin Yost said it was the bull's first competition at Wagin.

The bull was interbreed champion at last year's Perth Royal Show.

Mr Yost said the easy-moving bull would soon head to Sydney to be shown and promoted for semen sales, before being used as a stud sire on Liberty's Toodyay property.

During the Charolais judging Mr Hurst described the bull as balanced with tremendous length and muscling.

"He's got that natural softness, is very structurally correct and is a bull that is going to have a big industry future," he said.

In February the bull's paternal brother topped the WA Charolais Bull Sale in Bruswick, selling for $21,000.

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Supreme sash to Liberty bull

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Total solar eclipse fans invade Faeroe Islands for a rare glimpse of blackout

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A visitor looks at solar eclipse posters displayed for sale at the tourist office, in Torshavn, the capital city of the Faeroe Islands, Wednesday, March 18, 2015. The Faeroe Islands, a semi-autonomous Danish archipelago, and Svalbard, a Norwegian archipelago in the Arctic Ocean, are the only two places in the world where, cloud cover permitting, a total solar eclipse can be viewed from land on Friday morning. (AP Photo/Matt Dunham)(The Associated Press)

Two women, walk beside the harbor, in Torshavn, the capital city of the Faeroe Islands, Wednesday, March 18, 2015. The Faeroe Islands, a semi-autonomous Danish archipelago, and Svalbard, a Norwegian archipelago in the Arctic Ocean, are the only two places in the world where, cloud cover permitting, a total solar eclipse can be viewed from land on Friday morning. (AP Photo/Matt Dunham)(The Associated Press)

A woman walks along a coastal road in Torshavn, the capital city of the Faeroe Islands, Wednesday, March 18, 2015. The Faeroe Islands, a semi-autonomous Danish archipelago, and Svalbard, a Norwegian archipelago in the Arctic Ocean, are the only two places in the world where, cloud cover permitting, a total solar eclipse can be viewed from land on Friday morning. (AP Photo/Matt Dunham)(The Associated Press)

Meteorologist Soren Jacobsen points towards the Faeroe Islands on a graphic showing the weather forecast for 09:00 GMT, approximately 40 minutes before Friday's total solar eclipse over the Faeroe Islands during a press conference in Torshavn, the capital city of the Faeroe Islands, Wednesday, March 18, 2015. The Faeroe Islands, a semi-autonomous Danish archipelago, and Svalbard, a Norwegian archipelago in the Arctic Ocean, are the only two places in the world where, cloud cover permitting, a total solar eclipse can be viewed from land on Friday morning. (AP Photo/Matt Dunham)(The Associated Press)

Solar eclipse postcards are displayed for sale at the tourist office, in Torshavn, the capital city of the Faeroe Islands, Wednesday, March 18, 2015. The Faeroe Islands, a semi-autonomous Danish archipelago, and Svalbard, a Norwegian archipelago in the Arctic Ocean, are the only two places in the world where, cloud cover permitting, a total solar eclipse can be viewed from land on Friday morning. (AP Photo/Matt Dunham)(The Associated Press)

TORSHAVN, Faeroe Islands For months, even years, accommodation on the remote Faeroe Islands has been booked out by fans who don't want to miss an almost three-minute-long astronomical sensation. Now they just have to hope the clouds will blow away so they can fully experience Friday's brief total solar eclipse.

Scores of eclipse chasers and scientists have invaded the archipelago armed with telescopes, cameras and glasses for safe direct solar viewing ahead of the big event.

The weather forecast is better more than 2,000 kilometers (1,270 miles) to the northeast, in the Arctic islands of Svalbard, where spectators can hope for a clear day. The full eclipse will only be seen in a narrow path across the northern hemisphere, reaching the Faeroes at 0945 GMT on Friday.

"This is our 10th total eclipse. We love to watch them and being able to look at the corona with your eyes in the middle of the eclipse is really an exciting moment, to experience the diamond rings coming and going," said Les Anderson, a 60-year-old from San Diego, California, in Torshavn, capital of the Faeroes.

The population of the 18 rocky islands between Scotland and Iceland has swelled by approximately 10,000 for a few days from its normal 48,000 souls.

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Total solar eclipse fans invade Faeroe Islands for a rare glimpse of blackout

Total solar eclipse Friday: Skywatchers throng remote islands

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TORSHAVN, Faeroe Islands (AP) -- For months, even years, hotels on the remote Faeroe Islands have been fully booked by fans who don't want to miss an almost three-minute-long astronomical sensation. Now the sky gazers just hope the clouds will blow away so they can fully experience Friday's total solar eclipse.

Scores of eclipse chasers and scientists have invaded the archipelago armed with telescopes, cameras and glasses for safe direct solar viewing ahead of the big event.

The weather forecast is better 1,200 miles to the northeast, in the Arctic islands of Svalbard, where spectators can hope for a clear day. The full eclipse will only be seen in a narrow path across the northern hemisphere, reaching the Faeroes at 0945 GMT (2:45 a.m. PDT) on Friday.

"This is our 10th total eclipse. We love to watch them and being able to look at the corona with your eyes in the middle of the eclipse is really an exciting moment, to experience the diamond rings coming and going," said Les Anderson, a 60-year-old from San Diego, California, in the Faeroe capital of Torshavn.

The population of the 18 rocky islands between Scotland and Iceland has swelled by approximately 10,000 for a few days from its usual 48,000 souls.

"There has never, never been so many people on the islands before," said Theresa Kreutzmann, head of the tourism office in Torshavn.

The two best places to fully experience the total solar eclipse are the Faeroes, where the moon covers the sun completely for 2 minutes 45 seconds, and Svalbard, more than 800 kilometers (500 miles) north of the Norwegian mainland, where it will be 15 seconds shorter.

A partial solar eclipse can be seen across Europe and parts of Asia and Africa. Britain's Meteorological Office says 95 percent of the sun will be covered in the Hebrides, Orkneys and Shetland Islands.

Although Faeroe camping sites have opened ahead of time for those willing to brave nighttime temperatures of around 1.5 degrees Celsius (35 degrees Fahrenheit), authorities on Svalbard have reminded last-minute visitors that bringing a sleeping bag and finding a cozy corner for the night is not an option. The thermometer there hovers around minus 15 degrees Celsius (5 degrees Fahrenheit). And then there are the polar bears, which roam freely -- meaning that people need to carry firearms when moving outside settlements.

On average, three bears are shot in self-defense every year on Svalbard with an estimated polar bear population of 3,000 -- roughly the same as the human population. Visitors have been attacked. Just Thursday, a bear attacked a tent in which a Czech tourist was sleeping, slightly injuring him. In 2011, a British teenager was fatally mauled by a bear that attacked the tent he was sleeping in.

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Total solar eclipse Friday: Skywatchers throng remote islands

Chromosome shattering may be a hidden cause of birth defects

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IMAGE:This is a diagram of chromosome shattering. view more

Credit: Mirjam de Pagter

The human genome can be very forgiving. When children inherit chromosomes from their parents, some minor genetic changes frequently occur with few, if any, consequences. One exception, as researchers report in the March 19 issue of the American Journal of Human Genetics, is chromosomal shattering, termed chromothripsis, which the authors found in healthy mothers who had each given birth to a severely affected child. The findings could have important implications for genetic testing and issues related to infertility.

"Our study shows that despite its dramatic effects on chromosomal architecture, chromothripsis--which involves shattering of one or multiple chromosomes followed by random reassembly--does not necessarily lead to disease," says senior author Wigard Kloosterman, PhD, of University Medical Center Utrecht, in The Netherlands. "However, the presence of this phenomenon in healthy individuals impacts reproduction by leading to difficulties getting pregnant, miscarriages, and the birth of children with multiple birth defects, including intellectual disability."

Dr. Kloosterman and his team studied three families whose children suffer from multiple abnormalities due to chromothripsis that they inherited from their mothers. Although the children's mothers were unaffected or only mildly affected, the women's genomes harbored even more genome breakage than their children's. Two of the mothers had experienced prior difficulties with getting pregnant, which was probably associated with their complex genomic rearrangements.

Although these results highlight the amazing ability of the human genome to tolerate gene disruption, they also indicate that chromothripsis can impact female reproduction and should be considered during counseling of couples dealing with infertility.

Dr. Kloosterman noted that it is difficult to estimate the frequency of chromothripsis in the general population, and many of the commonly used analytical techniques lack the resolution to detect it to its full extent. The chromothripsis in the three mothers in this study was balanced, meaning that there were no deletions or duplications (changes in the number of copies of a gene) of any of the genes that were rearranged. Two children inherited only a subset, rather than all, chromothripsis chromosomes from their mother. In the third family, an additional rearrangement occurred during chromosome transfer to the child. In all three children, the alterations resulted in deletions and duplications of chromosomal regions, which most likely explains the children's birth defects.

"If one would solely perform currently widely used array-based diagnostic tests for detecting the number of copies of a gene in these families, one would only detect the genomic defects in the children but fail to detect the changes in the mother," said Dr. Kloosterman. "This would lead to a substantial underestimation of the recurrence risk for future pregnancies." Therefore, it is important to use a combination of genetic screening techniques, preferably whole-genome sequencing, in certain cases, he explained.

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This research was supported by the Child Health priority program from the University Medical Center Utrecht.

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Chromosome shattering may be a hidden cause of birth defects

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