Paradise found: 12 crowd-free Asia island escapes – CNN

As zealous souvenir hawkers follow busloads of tour groups to Asia's most famous islands, discerning travelers must look farther afield for more authentic getaways.

The good news? Whether your idea of paradise involves a tropical beach framed by palm trees, or wildlife encounters in the woods, Asia has an island for you.

From Indonesia to India, we've singled out a dozen of the best throw-back islands -- places where traditional cultures and unspoiled landscapes will transport travelers back in time.

Hidden away off the coast of Cambodia in the Gulf of Thailand, Koh Rong feels like a trip through time.

The low-key island offers a glimpse of what Ko Samui was like 30 years ago.

While both the American and French versions of "Survivor" TV show were filmed in Koh Rong, the island is still far from the typical tourist track.

With 23 beaches, Koh Rong offers plenty of options for sun, sea and sand, while the heavily forested interior beckons those in search of raw nature.

A tiny island off the west coast of Malaysia, Pangkor is overshadowed by heavyweight destinations like Penang and Langkawi.

But that's a good thing for anyone who longs for a more authentic experience.

Pangkor's east coast is spangled by stilt houses in old-fashioned kampong villages, where fishing and boat-building are still the main occupations.

Meanwhile, the gorgeous west coast offers white-sand stretches wrapped around turquoise bays.

Among local landmarks are the ruins of the 17th-century Dutch Fort and Fu Lin Gong Temple, with its extravagant Taoist sculptures and miniature version of China's Great Wall.

The area is teeming with wildlife, running the gamut from pangolins (like small, scaly anteaters) to colorful hornbills, flying foxes, "dugong" manatees, sea turtles and dozens of coral and tropical fish species.

In addition to wildlife, Lampi is also a refuge for the Moken "sea gypsies" -- one of Myanmar's smallest ethnic groups -- who have lived on the island for generations.

Within the national park boundaries are five Moken villages, as well as several related spiritual and cultural sites.

The largest Moken village is located on neighboring Bo Cho island -- part of Myanmar's first marine national park, established in 1996.

The institute maintains a research station on Bo Cho with a small museum dedicated to Lampi's flora, fauna and Moken heritage.

Framed by the Bay of Bengal and the Andaman Sea, the Andaman archipelago is a mash-up of modern mainland India and old-world keepsakes -- not to mention countless beaches, bays and coral reefs.

In this tropical backwater, visitors can mingle with the early morning cows and fishermen on Corbyn's Cove Beach, or scuba in the warm waters of Mahatma Gandhi Marine National Park, and soak up the exotic sights and smells of Aberdeen Bazaar in Port Blair -- the capital of the Andaman and Nicobar Islands.

Once a far-flung bastion of the British Empire, the Andamans are flush with colonial relics.

Explore the jungle-shrouded ruins on Ross Island, the gallows on Viper Island and the infamous Cellular Jail -- where murderers and political prisoners were once incarcerated.

Anchoring the southwest corner of the Philippines, Palawan is a largely undeveloped island that channels the wild vibe of nearby Borneo, in Malaysia.

The island's natural treasures include eerie Puerto-Princesa Subterranean River and the pristine coral gardens of super-remote Tubbataha Reefs Natural Park -- both UNESCO World Heritage Sites.

Along the northwest coast, Long Beach near San Vicente is the longest white-sand strand in the Philippines -- eight miles (13 km) of pristine shoreline that's so far unsullied by anything resembling a high-rise hotel or modern resort.

That's not to say there aren't cool places to crash nearby.

One of the Amami islands south of the Japanese mainland, Tokunoshima is known for its bloodless bullfighting.

The bovine equivalent of sumo wrestling, the events see massive bulls try to push one another out of a ring surrounded by cheering farmers -- many of whom placed bets on the beasts.

Aside from quirky past times, Tokunoshima also draws those in the know to its pristine coral reefs -- as one of the most secluded places to scuba or snorkel in the western Pacific.

Empty beaches, weird coastal rock formations and obscure World War II landmarks add to the island's offbeat allure.

Tokunoshima is famous for yet another reason: longevity.

The island is home to the world's highest percentage of people living beyond 100 years.

Japanese centenarian Shigechiyo Izumi (1865-1986), who reached the age of 120, claimed a daily swig of shochu -- local sugarcane wine -- was the secret to his ripe old age.

Southeast Asia meets the South Pacific in this exotic archipelago, located off the west coast of New Guinea in far eastern Indonesia.

Considered one of the world's top dive spots, Raja Ampat is home to largely untouched coral reefs that are teeming with biodiversity.

Above the surface, Raja Ampat's dramatic karst topography -- think southern Thailand without a thousand hotels -- is ripe for jungle walks and rock climbing.

But it takes some work to reach this scuba divers' paradise.

Floating far out in the Sea of Japan, this remote volcanic island can only be reached by ferry.

Despite its isolated position about 75 miles east of mainland South Korea, Ulleung-Do has been inhabited since 300 BC.

Today, the island sustains a thriving fishing community and budding tourist industry.

Adventure travelers appreciate the island's silver magnolia forest and steep volcanic terrain.

There's also a 43-mile (70 km) bike path, as well as an opportunity for scuba diving and sea kayaking along the dramatic sea cliffs.

Ulleung draws a following for its unique culinary traditions too.

The must-try dishes include fresh-off-the-boat raw seafood, organic barbecued beef bulgogi from island-bred cows, and "sanchae bibimbap" -- steamed rice served with wilds herbs, vegetables and roots foraged on the island.

Once a penal colony known as the Devil's Island of French Indochina, this 16-island archipelago off the Mekong Delta has turned to more peaceful pursuits in modern times.

History buffs will revel in the island's role in the age of ocean exploration -- Marco Polo allegedly stepped ashore at Con Dao on his long return journey to Venice.

To learn more about the island's war-plagued past, travelers can explore the Revolutionary Museum -- located in the former French commander's residence -- or tour the old prisons on the main island.

The best way to get around Con Dao is via motorbike, easy to hire from most hotels or a local rental outfit.

Con Dao is a haven for outdoorsy types too, with plentiful scuba, snorkeling and fishing opportunities.

Between May and October, visitors can watch sea turtles lay their eggs, while the infants hatch and scramble into the sea.

Thailand's beach scene is constantly changing, as resort areas expand to accommodate increasing tourist numbers.

But one island that continues to retain its retro past is Koh Phayam, off the coast of southern Ranong province in the Andaman Sea.

There is much debate about whether the island -- when seen from above -- resembles a giant manta ray or a massive kangaroo kicking its feet into the air.

But one thing is for sure: Koh Phayam is blissfully empty compared to Thailand's better known islands.

Phayam has a year-round population of just 500 people -- and there aren't many tourists either.

Most of the action centers around crescent-shaped Aow Yai Bay -- also known as Long Beach or Sunset Beach.

It's the go-to venue for beachfront dining, as well as after-dark parties.

Between May and October, the Indian Ocean churns up surfable waves along Aow Yai.

No matter what the time of year, Koh Phayam offers scuba and snorkeling, cycling, motorbiking, kayaking and surf fishing.

A stop on Southeast Asia's old hippie trail, Samosir Island in north-central Sumatra offers a trip through time to the 1970s and '80s.

The volcanic island is known for its stunning location -- in the middle of Lake Toba, the largest volcanic lake in the world.

The lakeside cafes, bars and bungalows of Tuk Tuk village cater to a mix of young backpackers and intrepid older travelers, fhe latter in search of a place that summons snippets of the days when Bali had a similar carefree -- and budget-friendly -- vibe.

Samosir is also a stronghold of local Batak tribal culture, as well as a great place to hire a scooter for a cruise through the nearby rice paddies.

A meandering coastal road leads north from Tuk Tuk to the megalithic monuments of Ambarita -- an ancient Batak tribal village -- and the museum complex in Simanindo, where travelers can catch daily Batak dance performances.

While much of Japan's huge northern island has been developed, a few corners of Hokkaido still offer a wild, untouched atmosphere.

Inhabited by brown bears, sea eagles and a host of other creatures, the island's diverse landscape features snow-capped volcanoes, hot springs, lakes and temperate northern forests.

The trees explode with color each fall and shed a sea of blossoms each spring.

Another draw is the traditional Japanese onsen -- hot spring -- culture.

Hokkaido boasts 23 hot spring areas and 11 different types of onsen, from simple thermal and sulfur to lesser-known radium, ferruginous (iron oxide) and cupriferous (copper) springs.

Joe Yogerst is a freelance travel, business and entertainment writer based in California.

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Paradise found: 12 crowd-free Asia island escapes - CNN

Tiwi Islands Sistagirls return home after their first Mardi Gras – ABC Online

Updated March 10, 2017 11:40:56

Stairs are lowered from a ferry onto the rocky red beach of Bathurst Island, and a group of Sistagirls descend, waving like royalty.

"From drag queen to drag suitcase," says Jason De Santis wryly, as he and Sistagirl Nicole Miller lug their suitcases up the beach.

"I feel like we're walking up the bloody hill of Oxford Street now. I'm glad I've got thongs on. And they're on my feet!"

Also known as drag queen Foxy Empire, Mr De Santis supported the Sistagirls Tiwi Island trans women at their first Mardi Gras, and was part of the group of about 30 who travelled the 6,000-kilometre round trip to strut their stuff in Sydney for their debut at the city's iconic Mardi Gras parade last Saturday.

"It just went fabulous, we was all overjoyed, we couldn't even think that we was there," Ms Miller said.

"My heart was trembling, I couldn't believe it, I was over-excited."

The group spent several months crowdfunding so they could afford to strut their stuff down Oxford Street and show off their unique blend of LGBTIQ and Tiwi culture.

"The vibe as we were getting ready, it was quite exciting," Mr De Santis said.

"It wasn't until the girls actually got into the line with the float that they realised how big this was, and that there were people lined on the streets waiting just to see them."

Ms Miller said she felt embraced by the community as the Sistagirls paraded down Oxford Street.

"I was really happy with that too and all my other girls, the support and people around us, that was just explosive, I couldn't believe my eyes," she said.

"I'm glad I'm back home, it's just like I'm bringing Sydney back here."

The girls are already looking ahead to next year's march.

"I'm really looking forward to the following years of Mardi Gras and seeing how this NT float will grow and what it's going to look like, because the difference between now and three years ago when it started is huge," Mr De Santis said.

"I don't think the Sistagirls are never going to not be on a float now."

And he's extending a hand to the rest of the LGBTIQ community to join them.

"This year was about the Sistagirls, we set the bar now, but we want more of those people from the community," he said.

"From the desert to the sea, if you want to put your hand up do it, this is the introduction to the world out there that can support us."

But for now, the exhausted but happy group are back home on the island and keen to begin their recovery.

"After doing the golden mile in eight-inch heels, my feet are so sore," Mr De Santis said.

"I just can't wait to be eating fish, oysters, crab, anything that swims in the sea, I want it to be in my belly."

Topics: gays-and-lesbians, people, indigenous-aboriginal-and-torres-strait-islander, darwin-0800

First posted March 10, 2017 11:30:10

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Tiwi Islands Sistagirls return home after their first Mardi Gras - ABC Online

Islands’ biodiversity reflected in plant species – Otago Daily Times

Among the many treasures in Dunedin Botanic Garden are some of the most rare and wonderful plant species in the flora of Aotearoa: the offshore island plants.

New Zealand's estimated 600 offshore islands are biodiversity havens, spread over 2800km from the almost-subtropical Kermadec Islands to the subantarctic Campbell Island group. Plants from these islands are often larger than their mainland relatives, with bold, chunky foliage and sometimes big, brilliant flowers.

A handful of offshore island species have become common in gardens, but many are unavailable in nurseries and notoriously difficult to grow. Over the years, staff at the botanic garden have had opportunities to collect and grow some of these special plants for visitors to enjoy.

We tuck away beauties from subtropical islands, such as the Three Kings group, into frost-free spots under trees. Despite this, many specimens were severely knocked back by unusually cold temperatures last winter. All is not lost and most, such as the stunning, critically threatened climber Tecomanthe speciosa, have put on promising new shoots.

Dunedin Botanic Garden has a substantial collection of plants from the Chatham Islands, the remote salt-blasted archipelago 800km east of Banks Peninsula. These range from garden favourites such as Chatham Island forget-me-nots (Myosotidium hortensia) to the seldom-seen hoho/Chathams lancewood (Pseudopanax chathamicus) and the swamp mapou (Myrsine coxii).

Subantarctic island species are successfully growing in the native collection too. Mega-herbs like the punui (Stilbocarpa polaris), grown from seed collected two years ago from the Auckland Islands, are beginning to look lush.

-Kate Caldwell is curator of the native plant collection at Dunedin Botanic Garden.

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Islands' biodiversity reflected in plant species - Otago Daily Times

The most relaxing beaches and islands in Queensland and the Northern Territory – Telegraph.co.uk

The Great Barrier Reef has a wide variety of islands, some of them protected or too small to inhabit, others providing fantastic opportunities to bask in incredible surroundings.

Located 150 miles north of Cairns and 60 miles off the coast of Cooktown and accessible by boat or plane, Lizard Island is Australias northernmost island resort, an isolated tropical paradise perfect for relaxing in. The highest vantage point on the island, Cooks Look, is a beautiful spot for a picnic.

Just nine miles off the coast of Port Douglas, the Low Isles comprises two islands: uninhabited Woody Island, composed of coral and mangrove; and Low Island, a sandy coral cay. They are a great place to spend some peaceful and relaxing time.

A tiny island cay 45 minutes from Cairns, Green Island is small enough to walk around in 20 minutes. Its size only serves to exaggerate the vast expanse of azure sea surrounding it. Theres a small resort and a lush rainforest interior; otherwise it belongs to the birds and anyone who chooses to explore it. There are also facilities on the island for day-trippers.

One of the more rugged islands, Fitzroy Island is actually a peak in a chain of mountains that extends off the coast from nearby Cairns. Despite its proximity to the town, it is isolated and quiet, with much of it given over to national parkland. Theres a resort with extensive facilities to ensure the stress and strain of everyday life feels a million miles away.

The Frankland Islands are a cluster of five islands south of Cairns. They are completely uninhabited, ringed by white sand, covered in lush vegetation and inhabited by exotic birds. Because they are protected, operators need a licence to visit these islands so it is always peaceful, and camping is only permitted on two of the islands, Russell and High.

Cairns itself has two excellent spots, Trinity Beach and Palm Cove, just outside the centre. The former is quieter and more upcoming; the latter is populated by numerous boutiques and restaurants. Further up the Queensland coast, Port Douglas is a pretty, chilled-out village surrounded by rainforest and beautiful beaches, notably Four Mile Beach, a long stretch of white sand fringed by palms. There is plenty to do in town, but the place really livens up with Carnivale (26-28 May), a weekend-long festival with parades, music, arts, comedy and seafood stalls.

Only a short, two-and-a-half-hour flight away, the Northern Territory has plenty of very special places to chill on the water. The most accessible are the city beaches in Darwin, especially Mindil Beach, where locals and travellers enjoy mango ice creams and roo burgers at the twice-weekly sunset markets (April to October on Thursdays and Sundays). Families will love Darwins wave pool and swimming lido, while its waterfront area has a smart and sophisticated feel offering a wide choice of bars, cafes and restaurants for you to wind down in.

Meanwhile for a pub crawl with a difference in the Northern Territory, Airborne Solutions Heli Pub tour is a good excuse for a spin round the Top Ends most popular and quirky watering holes, such as the Lodge on Goat Island and the Humpty Doo Hotel.

Another popular day trip from Darwin visitors could consider would be to the Tiwi Islands Bathurst and Melville. They are almost entirely populated by indigenous people and well-respected for their arts and crafts.

Finally, for the ultimate get-away-from-it adventure, Banubanu Wilderness Retreat offers a castaway experience on Bremer Island off East Arnhem Land. Unwind, watch the wildlife and interact with the local indigenous people for an insight into a different way of life.

Tropical North Queensland and the Northern Territory are two of the most interesting, exciting and accessible regions in Australia, offering some of the shortest flying times from the UK direct into Darwin and Cairns, as well as year-round appeal.

These two regions offer an array of incredible experiences including the icons of the Great Barrier Reef and Uluru, amazing wildlife, nature, islands and beaches, as well as great food and wine. Booking with Flight Centre, your holiday to Queensland and the Northern Territory, will be perfect and protected.

For more reasons to book a holiday with Flight Centre to Tropical North Queensland and the Red Centre,visitflightcentre.co.uk

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The most relaxing beaches and islands in Queensland and the Northern Territory - Telegraph.co.uk

Exhibit at Morrill Hall transports you to the Galapagos Islands – 1011now

LINCOLN, Neb. If youre in need of a vacation, you can take a trip to the Galapagos Islands without even leaving Nebraska. An exciting traveling exhibit just opened at Morrill Hall in Lincoln.

The Galapagos exhibit transports you to a chain of islands 600 miles off the coast of Ecuador in South America. If you visit the museum, you can explore the islands to learn about plants and animals found there.

We provide a field guide for you to wander through the islands as you visit this extraordinary place, said Dr, Judy Diamond, Professor and Curator at the University of Nebraska State Museum.

Visitors will also be able to examine a variety of specimens, including a newly discovered butterfly species; and play with 10 touch-screen stations offering games and videos.

You can hear the sounds and sights of the Galapagos Islands. You can also engage in interactive exhibits where you get to play the role of the scientist and measure the beaks of finches to see how they relate to different ecological conditions that produce different kinds of seeds said Dr. Diamond.

The Galapagos Islands helped Charles Darwin develop his theory of evolution by natural selection. Since then, other important biological discoveries have occurred in the Galapagos. The islands continue to be a research mecca for biologists and a unique travel destination for nature enthusiasts.

These islands are a very special place, said Dr. Diamond. They were formed less than four million years ago and they arose from volcanoes under the ocean.

The exhibit is open until August, but during the month of March, the museum is hosting events to celebrate the opening.

Investigate: Second Saturday Science Lab is March 11 from 10 a.m. to Noon. That event allows visitors to learn about reptiles that live in the Galapagos and see box turtles. To learn more click here.

After that, Science Caf: From Nebraska to the Galapagos is March 16 from 6:30 p.m. to 8:00 p.m. That event is a casual, educational and entertaining monthly series for adults 21 and older exploring a variety of science and natural history topics. For more information on that event, click here.

For general information the exhibit and what it has to offer, click here.

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Exhibit at Morrill Hall transports you to the Galapagos Islands - 1011now

Mutations in CWC27 result in spectrum of conditions – Baylor College of Medicine News (press release)

An international team of researchers has discovered that mutations in the human gene CWC27 result in a spectrum of clinical conditions that include retinal degeneration and problems with craniofacial and skeletal development. The results appear in the American Journal of Human Genetics.

CWC27 is a new disease-associated gene, said co-senior author Dr. Rui Chen, associate professor of molecular and human genetics at Baylor College of Medicine.

One of the goals of the Chen lab is to identify genes involved with human retinal disease, such as retinitis pigmentosa, a condition characterized by progressive development of night blindness and tunnel vision, sometimes from the early age of 2. Retinitis pigmentosa is the most common inherited disorder of the retina; it affects nearly 1 in 4,000 people, and more than 1 million are visually impaired around the world due to this untreatable disease.

In our search for genes linked to retinitis pigmentosa, we identified a patient with the condition more than two years ago, said co-first author Mingchu Xu, graduate student in molecular and human genetics in the Chen lab. We identified a frameshift mutation in CWC27. The patient did not have other conditions in addition to the vision problems. To study the condition, we mimicked the human mutation in a mouse model, and at 6 months of age the mice showed retinal degeneration and no other conditions, just as we had observed in the human patient.

CWC27 is one of more than 100 genes that participate in the formation and function of the spliceosome, a molecular machine that is involved in the correct expression of the proteins that carry out the functions of all the cells in the body. Until now, most disease-associated genes of the spliceosome had been involved in two non-overlapping conditions. For instance, mutations in certain proteins of the spliceosome cause syndromes that involve mainly craniofacial and skeletal conditions, while mutations in other spliceosome genes result only in retinitis pigmentosa. CWC27 seemed to belong to the second group of genes.

Surprising results

Interestingly, our collaborator Dr. Daniel Schorderet, director of the Institute for Research in Ophthalmology in Switzerland and co-senior author of the paper, was working with patients who have mutations in CWC27 and present with more severe clinical conditions than our patient, including craniofacial and skeletal problems in addition to problems with vision, Xu said.

When we looked at the clinical characteristics of all the patients, we did not anticipate that they would have mutations in the same gene. Only when we looked at the genes did we realize that the spectrum of clinical characteristic in the patients was the result of various mutations in the same gene, CWC27, Chen said.

By applying exome sequencing to multiple families and modeling the disease in two mouse models the researchers were able to appreciate the spectrum of clinical conditions that mutations in the same gene can cause.

This is the first time a mutation of a gene in the spliceosome has been described to result in an entire spectrum of clinical conditions, Xu said. To explain why our patient presented only with vision problems, we hypothesized that the mutation in our patients CWC27 was milder than those of other patients. By analyzing the results on mouse models and patient samples, we found that the mutant gene in our patient probably retains a residual function, while the genes in the patients of the other groups have a more severe loss of function.

This study also shows the power of collaboration within the genetics community when looking for new disease-associated genes, Xu said. Initially, we only identified one patient and then we collected more cases via two platforms, GeneMatcher and the European Retinal Disease Consortium. We would not have been able to present this interesting story without the contributions of researchers from nine countries. With exome sequencing accessible to more patients and researchers, these platforms will most likely speed up the process of finding the genetic causes of human diseases.

Seea complete list of authors and their affiliations and the financial support for this project.

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Mutations in CWC27 result in spectrum of conditions - Baylor College of Medicine News (press release)

House Republicans would let employers demand workers’ genetic test results – STAT

A

little-noticed bill moving through Congress would allow companiesto require employees to undergo genetic testing or risk paying a penalty of thousands of dollars, and would let employerssee that genetic and other health information.

Giving employers such power is now prohibited by legislation including the 2008 genetic privacy and nondiscrimination law known as GINA. The new bill gets around that landmark law by stating explicitly that GINA and other protections do not apply when genetic tests are part of a workplace wellness program.

The bill was approved by a House committee on Wednesday, with all 22 Republicans supporting it and all 17 Democrats opposed. It has been overshadowed by the debate over the House GOP proposalto repeal and replace the Affordable Care Act, but the genetic testing bill isexpected to be folded into a second ACA-related measure containing a grab-bag of provisions that do not affect federal spending, as the main bill does.

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What this bill would do is completely take away the protections of existinglaws, said Jennifer Mathis, director of policy and legal advocacy at the Bazelon Center for Mental Health Law, a civil rights group. In particular, privacy and other protections for genetic and health information in GINA and the 1990 Americans with Disabilities Act would be pretty much eviscerated, she said.

Employers say they need the changes because those two landmark laws are not aligned in a consistent manner with laws about workplace wellness programs, as an employer group said in congressional testimony last week.

Top wellness award goes to workplace where many health measures got worse

Employers got virtually everything they wanted for their workplace wellness programs during the Obama administration. The ACA allowed them to charge employees 50 percent more for health insurance if they declined to participate in the voluntary programs, which typically include cholesterol and other screenings; health questionnaires that ask about personal habits including plans to get pregnant; and sometimes weight loss and smoking cessation classes. And in rules that Obamas Equal Employment Opportunity Commission issued last year, a workplace wellness program counts as voluntary even if workers have to pay thousands of dollars more in premiums and deductibles if they dont participate.

Despite those wins, the business community chafed at what it saw as the last obstacles to unfettered implementation of wellness programs: the genetic information and the disabilities laws. Both measures, according to congressional testimony last week by the American Benefits Council, put at risk the availability and effectiveness of workplace wellness programs, depriving employees of benefits like improved health and productivity. The Council represents Fortune 500 companies and other large employers that provide employee benefits. It did not immediately respond to questions about how lack of access to genetic information hampers wellness programs.

Rigorous studies by researchers not tied to the $8 billion wellness industry have shown that the programs improve employee health little if at all. An industry group recently concluded that they save so little on medical costs that, on average, the programs lose money. But employers continue to embrace them, partly as a way to shift more health care costs to workers, including by penalizing them financially.

Do workplace wellness programs improve employees health?

The 2008 genetic law prohibits a group health plan the kind employers have from asking, let alone requiring, someone to undergo a genetic test. It also prohibits that specifically for underwriting purposes, which is where wellness programs come in. Underwriting purposes includes basing insurance deductibles, rebates, rewards, or other financial incentives on completing a health risk assessment or health screenings. In addition, anygenetic information canbe provided to the employer only in a de-identified, aggregated form, rather than in a way that reveals which individual has which genetic profile.

There is a big exception, however: as long as employers makeproviding genetic information voluntary, theycan ask employees for it. Under the House bill, none of the protections for health and genetic information provided by GINA or the disabilities lawwould apply to workplace wellness programs. As a result, employers could demand that employees undergo genetic testing and health screenings.

While the information returned to employers would not include workers names, its not difficult, especially in a small company, to match a genetic profile with the individual.

That would undermine fundamentally the privacy provisions of those laws, said Nancy Cox, president of the American Society of Human Genetics, in a letter to the House Committee on Education and the Workforce the day before it approved the bill. It would allow employers to ask employees invasive questions about genetic tests they and their families have undergone and to impose stiff financial penalties on employees who choose to keep such information private, thus empowering employers to coerce their employees into providing their genetic information.

If an employer has a wellness program but does not sponsor health insurance, rather than increasing insurance premiums, the employer could dock the paychecks of workers who dont participate.

The privacy concerns also arise from how workplace wellness programs work. Employers, especially large ones, generally hire outside companies to run them. These companies are largely unregulated, and they are allowed to see genetic test results with employee names.

They sometimes sell the health information they collect from employees. As a result, employees get unexpected pitches for everything from weight-loss programs to running shoes, thanks to countless strangers poring over their health and genetic information.

Sharon Begley can be reached at sharon.begley@statnews.com Follow Sharon on Twitter @sxbegle

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House Republicans would let employers demand workers' genetic test results - STAT

Social phobia: Indication of a genetic cause: Study supports link with … – Science Daily


Science Daily
Social phobia: Indication of a genetic cause: Study supports link with ...
Science Daily
People with social anxiety avoid situations in which they are exposed to judgment by others. Those affected also lead a withdrawn life. Researchers have now ...

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Social phobia: Indication of a genetic cause: Study supports link with ... - Science Daily

Are You Middle Class Enough to Deserve a Health Care Tax Break? – New York Times

Are You Middle Class Enough to Deserve a Health Care Tax Break?
New York Times
My guess is that a majority of us would agree that health care is a bit more important than retirement savings and I.R.A.s, which in turn are more important than mortgage interest deductions for most people's long-term financial security. Encouraging ...

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Are You Middle Class Enough to Deserve a Health Care Tax Break? - New York Times

Medical, Hospital Groups Oppose GOP Health Care Plan – NPR

The Republican health care overhaul faces opposition from many in the medical establishment. J. Scott Applewhite/AP hide caption

The Republican health care overhaul faces opposition from many in the medical establishment.

The Republican health care overhaul working its way through the House is opposed by Democrats and by many Republican conservatives. It's none too popular with the people on the front lines of health care, either including doctors, nurses and hospitals.

The chief medical officer of Medicaid, Dr. Andrey Ostrovsky, tweeted out his opposition on Wednesday. "Despite political messaging from others at HHS, I align with the experts ... in opposition to #AHCA," the career staffer said.

Ostrovsky, who has been in his current job since September, has received praise from former Obama administration officials for speaking out.

Former Medicare and Medicaid chief Andy Slavitt called Ostrovsky a "hero."

Trump's Health and Human Services secretary, Tom Price, has been out front with other Republican leaders pitching the new bill. In a press briefing on Wednesday, he said the administration will be looking at Affordable Care Act regulations "and make certain that if they help patients, then we need to continue them. If they harm patients or increase costs, then obviously they need to be addressed."

The organizations Ostrovsky cited in his tweet that have voiced concerns are the American Academy of Family Physicians, the American Academy of Pediatrics and the American Medical Association.

The AMA sent a letter to congressional leaders saying it was unable to support the GOP bill largely due to the "expected decline in health insurance coverage and the potential harm it would cause to vulnerable patient populations."

Among other things, the AMA cited the proposed rollback of Medicaid expansions that happened under the Affordable Care Act, which the group called "highly successful in providing coverage for lower income individuals"; the proposed repeal of the Prevention and Public Health Fund, also established by Obamacare; and provisions targeting Planned Parenthood.

In a similar letter, the American Nurses Association said the Republican plan "threatens health care affordability, access, and delivery for individuals across the nation." It points to changes the bill would make to Medicaid and says the measure "restricts million of women from access to critical health services." The ANA says the proposed changes "in no way will improve care for the American people."

The American Hospital Association also weighed in, pointing out the Congressional Budget Office has yet to provide a cost estimate for the measure or say how it would change coverage levels. Without such analysis and "needed transparency," the group said, Congress "should wait" before proceeding.

It also points to the proposed restructuring of Medicaid, saying it will "have the effect of making significant reductions in a program that provides services to our most vulnerable populations, and already pays providers significantly less than the cost of providing care."

The opposition to the GOP plan from health care groups, who say its provisions need to be more generous, puts GOP leaders in a quandary. On the other side of the equation, conservative House members are opposing the measure because they believe it is too generous and doesn't go far enough to repeal subsidies in the Affordable Care Act.

The bill's authors have responded to the criticism. "There's a pretty big the medical-industrial complex in America," Rep. Greg Walden of Oregon, chairman of the House Energy and Commerce Committee, told reporters. "And when you touch it, I've discovered, it touches back."

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Medical, Hospital Groups Oppose GOP Health Care Plan - NPR

Happening Today: Health Care, South Korea, Travel Ban, EPA, Zuckerberg – NBC New York

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GOP Claims Momentum as Health Bill Clears Hurdles

Republican leadersdrove their long-promised legislation to dismantle Barack Obama's health care law over its first big hurdles in the House, claiming fresh momentum despite cries of protest from right, left and center. After grueling sessions, the Energy and Commerce and Ways and Means committees both approved their portions of the bill along party-line votes. The legislation, strongly supported by President Trump, would eliminate the unpopular tax penalties for the uninsured under the Affordable Care Act, replacing Obama's law with a conservative blueprint likely to cover far fewer people but Republicans hope increase choice. "This is the closest we will ever get to repealing and replacing Obamacare," Speaker Paul Ryansaid at a press briefing.

Legal Challenges to Trump's Travel Ban Mount From States

Legal challenges against President Trump'srevised travel banmounted as Washington state said it would renew its request to block the executive order. It came a day after Hawaii launched its own lawsuit, and Washington state Attorney General Bob Ferguson said both Oregon and New York had asked to join his state's legal action. Massachusetts Attorney General Maura Healey said the state is consolidating legal efforts and joining fellow states in challenging the revised travel ban. Trump's revised ban bars new visas for people from six predominantly Muslim countries: Somalia, Iran, Syria, Sudan, Libya and Yemen. It also temporarily shuts down the U.S. refugee program.

2 Die in Protests After South Korean President Ousted

In a unanimous ruling, South Korea's Constitutional Court formally removed impeachedPresident Park Geun-hye, the country's first female leader who rode a wave of lingering conservative nostalgia for her late dictator father to victory in 2012, from office over a corruption scandal that has plunged the country into political turmoil and worsened an already-serious national divide, prompting rowdy protests and celebrations that led to the death of two people. The ruling by the eight-member panel opens her up to possible criminal proceedings and makes her South Korea's first democratically elected leader to be removed from office since democracy replaced dictatorship in the late 1980s.

EPA Chief: CO2 Not Major Contributor to Warming

Environmental Protection Agency AdministratorScott Pruitt saidhe did not believe carbon dioxide was a primary contributor toglobal warming, a view contradicted by NASA and the National Oceanic and Atmospheric Administration, NBC News reported. It is also at odds with Pruitt's own promises during his nomination hearing before the U.S. Senate. But if Pruitt doubts the global scientist consensus that carbon dioxide is causing the Earth to warm, he did pledge during his confirmation hearing to regulate it in accordance with a U.S. Supreme Court ruling and an EPA finding that it was threatening public health.

Can Changing Weather Make You Sick?

Can the weather truly be to blame when you "feel under the weather?" "In a sense, yes,"says Dr. Michael Robinson, a family medicine resident at Louisiana's Lake Charles Memorial Health System. "Thecolder weathercauses people to go inside and be in closer proximity to each other, but as far as just becoming sick, the weather doesn't affect it." That means germs are spreading more indoors when the weather is less inviting outdoors. Still, some viruses replicate more easily in cooler weather, like the agents causing the common cold and influenza that spreads best when the air is cold and dry.

California Wants to Repeal HIV Laws

Exposing a person to HIV is treated more seriously under California law than infecting someone with any other communicable disease, a policy some lawmakers say is a relic of the decades-old AIDS scare that unfairly punishesHIV-positive peoplebased on outdated science. Several lawmakers are promoting a bill that would make it a misdemeanor instead of a felony to intentionally expose someone to HIV, the virus that causes the immune system-weakening disease AIDS. The change would treat HIV like other communicable diseases under California law.

Zuckerberg, Wife Expecting 2nd Girl

Mark Zuckerberg and his wife Priscilla Chan are expecting a second baby girl, theFacebook founderannounced in a post that paid tribute to his and his wife's sisters. In announcing his second daughter, Zuckerbergshared childhood family photosof their families and said what their sisters taught them: "to learn from smart, strong women" in Zuckerberg's case, "the importance of family, caring for others and hard work" in Chan's case.

Nicole Kidman Explains 'Seal Clap' at Oscars

Let's give Nicole Kidman a round of applause. Rather than come up with some excuse for her weird clapping during the 2017 Oscars, the "Lion" actress confirmed her Harry Winston rings were to blame. Kidman, who was nominated for Best Supporting Actress, wore119 caratsworth of Harry Winston diamonds, which included a cluster diamond ring. "It was really awkward!"she saidon "Kyle and Jackie O Show." "I was like, 'Gosh, I want to clap.' I don't want to not be clapping, which would be worse, right? 'Why isn't Nicole clapping?'"

Published 54 minutes ago | Updated 43 minutes ago

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Happening Today: Health Care, South Korea, Travel Ban, EPA, Zuckerberg - NBC New York

The Republican Health Care Crackup – New York Times


New York Times
The Republican Health Care Crackup
New York Times
Members and staff members on the House Energy and Commerce Committee finishing amendments to their portion of a health care bill on Thursday. Credit Stephen Crowley/The New York Times. The Republican health care bill could represent the moment ...

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The Republican Health Care Crackup - New York Times

After Halting Start, Trump Plunges Into Effort to Repeal Health Law – New York Times


New York Times
After Halting Start, Trump Plunges Into Effort to Repeal Health Law
New York Times
Today marks the beginning of the end of Obamacare, Mr. Scalise declared after House committee votes to advance the Republican's health care bill. Credit Doug Mills/The New York Times. WASHINGTON President Trump, after a halting start, is now ...
The Note: Trump in 'sell mode' on health careABC News

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After Halting Start, Trump Plunges Into Effort to Repeal Health Law - New York Times

Trump Tries To Sell Republican Health Care Plan To Conservatives – NPR


NPR
Trump Tries To Sell Republican Health Care Plan To Conservatives
NPR
March 10, 20175:12 AM ET. Heard on Morning Edition. Conservatives are revolting against the GOP health care measure. David Greene talks to David Urban, president of American Continental Group, and a former adviser to the Trump presidential campaign.

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Trump Tries To Sell Republican Health Care Plan To Conservatives - NPR

Warren rips GOP healthcare plan: ‘What planet are these guys living on?’ – The Hill

Sen. Elizabeth WarrenElizabeth WarrenOvernight Finance: Budget ref caught in ObamaCare crossfire | Treasury chief urges Congress to raise debt limit | McConnell says tax reform unlikely by August Warren rips GOP healthcare plan: 'What planet are these guys living on?' Dems press White House on Jared Kushner's financial holdings MORE (D-Mass.) on Thursday blasted the GOP's healthcare plan, urging lawmakers to drop the legislation aimed at replacing the Affordable Care Act.

"A health care bill that destroys care & affordable coverage for millions seriously? What planet are these guys living on?!" Warren wrote in a tweet.

"Its time to junk this cruel #Trumpcare bill before massive numbers of Americans are hurt by it," she added.

A health care bill that destroys care & affordable coverage for millions seriously? What planet are these guys living on?!

The White House and GOP leaders have moved to aggressively pitch the legislation, dubbed the American Health Care Act, which they introduced on Monday and hope to vote on within weeks.

The healthcare bill has been met withintense criticismfrom numerous groups representing doctors and hospitals, as well as the American Medical Association, advocacy group AARP and an internal organization from the American Cancer Society.

Conservative groups such as Americans for Prosperity have also come out against the bill, while groups such as the U.S. Chamber of Commerce and Americans for Tax Reform have backed the GOP effort.

"Republicans seem intent on plowing ahead anyway pretending down is up, left is right, & #Trumpcare is somehow not a catastrophe," Warren argued on Twitter.

"The GOP have convinced people who never agree on ANYTHING docs, hospitals, economists, even insurance companies: #Trumpcare is a disaster."

Republicans seem intent on plowing ahead anyway pretending down is up, left is right, & #Trumpcare is somehow not a catastrophe.

The GOP have convinced people who never agree on ANYTHING docs, hospitals, economists, even insurance companies: #Trumpcare is a disaster.

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Warren rips GOP healthcare plan: 'What planet are these guys living on?' - The Hill

GOP learns health care is, indeed, complex: #tellusatoday – USA TODAY

USA TODAY 4:25 p.m. ET March 9, 2017

House Speaker Paul Ryan during a news conference in Capitol Hill on March 9, 2017.(Photo: J. Scott Applewhite, AP)

Letter to the editor:

President Trump is starting to get a great lesson on the difference between campaigning and actually governing.

While campaigning you can hurl accusations like Obamacare is a disaster and it must be repealed and replaced immediately. When you win, as Trump did, you now have to deliver, and there is the rub. Delivering a health care product that is better, cheaper and still fair is an incredibly difficult task.

The far right of the presidents own party says the initial plan is simply Obamacare lite. The left says it will cause millions to lose their health care coverage. Meanwhile, the Congressional Budget Office is expected to project a very high price tag that undermines the promise of better and more affordable insurance.

You can readily question the political savvy of the Trump team. While its political capital was high, it could have chosen to start with the more popular and less controversial tax and regulatory reform. Then use these victories and resultant goodwill as a springboard to launch into health care reform. Its too soon to dub this foray Trumps Waterloo moment, but it clearly is a challenge to his young presidency.

Stay tuned to see how Trumpcare unfolds!

Ken Derow; Swarthmore, Pa.

Facebook comments are edited for clarity and grammar:

Why is it that people cannot accept that a public option fixes most of this? I do welcome the Republicans plan, but it doesnt solve the specific issues it needs to address to ensure coverage for all.

William Worsham

Just like with Obamacare, Congress is focused on the wrong problem: Who pays, instead of bringing down the total cost of the system. We need to bring competition to the health care system and increase supply faster than demand. That is the only way to bring down costs.

First, everyone from insurers to government employees to private individuals should have to pay the same rate. That rate should be posted, for everyone to see and encourage competition.

Second, you need to increase quality care faster than the cost of care, the opposite of what these expansions do. That will allow competition to drive these costs down. We need to get rid of all the bureaucratic hurdles.

Finally, if you are getting government assistance, you should be doing everything you can to keep the costs down. There should be a requirement to be fit medical conditions permitting.

Mathew Andresen

Republicans rename Obamacare, call it a day: #tellusatoday

Our followers shared their thoughts on the American Health Care Act. Tweets are edited for clarity and grammar:

Lets pass it so we can find out whats in it. #DemcratsPlaybook

@tngarrett

Comparisons between the Affordble Care Act and the AHCA are truly odious. Obamacare was too disastrous to ever fully implement, while Trumpcare is only partly formulated.

@billbradbrooke

I dont know how House Speaker Paul Ryan sleeps at night knowing the lower class is left in the cold.

@CathyScero

For more, follow @USATOpinion and #tellusatoday.

Read or Share this story: http://usat.ly/2mr3dev

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GOP learns health care is, indeed, complex: #tellusatoday - USA TODAY

Shortcuts? Insulin, other medicines developed faster with genetic engineering – Genetic Literacy Project

Given that its accomplishments include the domestication of plants and animals, biotechnology is practically synonymous with civilization itselfOver the last couple of centuries, a more systematic approach has been devised.

An explosion of discoveries in the 19th and 20th centuries ushered in the modern era of biotechnologyLearning about everything from enzymes to hormones to vitamins meant medical researchers could deliberately design drugs to target specific problems. The new information also showed them how to go about producing these medications by tapping into natural biological processes.

The main steps of biotech medication development consist of determining the biologic source of a desired medication, mass-producing the source, extracting and purifying the medication, and preparing the medication for use.

The introduction of genetic engineering has altered the first step in creating biotech medicine. Instead of simply identifying a biological entity that produces the desired substance, an organism is literally created for this purpose.

For more sophisticated pharmaceuticals, engineered animal cells are used instead of bacteria.

The GLP aggregated and excerpted this blog/article to reflect the diversity of news, opinion, and analysis. Read full, original post: How are Biotechnology Medicines Made?

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Shortcuts? Insulin, other medicines developed faster with genetic engineering - Genetic Literacy Project

Amid advances in gene therapy, ‘bubble baby’ in SF gains hope – San Francisco Chronicle

JaCeon Golden has only ever known the inside of hospitals. But the treatment hes receiving may have implications far beyond his as-yet isolated life.

Round-faced and big-eyed, with a perpetual pout that belies his sunny nature, he looks as healthy as any other 5-month-old. But JaCeon was born without a functioning immune system. Even the most banal of infections a cold, a diaper rash could be deadly.

Earlier this year, JaCeon became the first baby at UCSF Benioff Childrens Hospital at Mission Bay to undergo an experimental gene therapy treatment that, doctors hope, will nudge his body to build a new, robust immune system.

From right: Dannie Hawkins checks on her nephew Ja'Ceon Golden, who is being held by patient care assistant Grace Deng at UCSF Benioff Children's Hospital on Wednesday, March 8, 2017, in San Francisco, Calif. Golden, who is five months old, is diagnosed with severe combined immunodeficiency disease (SCID). He is a patient at UCSF, where he stays in a sterile room. The hospital is working on a new gene therapy treatment for SCID. Hawkins brought her nephew Golden from New Mexico for the experimental treatment.

From right: Dannie Hawkins checks on her nephew Ja'Ceon Golden, who...

So far, his results are promising. In a few weeks, JaCeons great aunt, whos also his guardian, hopes to introduce him to the world outside.

Am I going to see him smile when we walk out of here? Dannie Hawkins, 52, said with a glance at the baby, being fed from a bottle by a nurse wearing a gown and gloves. Hows he going to do in the free world?

It will be a while months, probably years before JaCeon is able to fully integrate with that wide world: go to school and birthday parties, ride a public bus, swim in a community pool. But that those activities may be in his future at all is extraordinary.

The treatment given to JaCeon is the result of decades of research into gene therapy that included a string of striking failures that led many doctors to abandon the pursuit altogether.

Gene therapy long had been considered a potential treatment for severe combined immunodeficiency disorder, or SCID, the condition JaCeon was born with, and some other genetic syndromes. The idea is to replace a single gene thats causing trouble.

Even as many doctors gave up on the promise of gene therapy, teams of stubborn scientists kept plugging away. And a few years ago, their experiments started to work, propelled by advances in the understanding of stem cells in this case, a type called hematopoietic stem cells that live in bone marrow and are responsible for generating blood and immune cells and improved methods of delivering genetic repairs.

JaCeon Golden is treated by patient care assistant Grace Deng (center) and pediatric oncology nurse Kat Wienskowski.

JaCeon Golden is treated by patient care assistant Grace Deng...

Now human gene therapy is being tested in trials at UCLA, where a team has treated 20 children with one type of SCID, and at UCSF in collaboration with St. Jude Childrens Research Hospital in Memphis. Both trials are funded by grants from the California Institute for Regenerative Medicine, the states stem cell agency, located in Oakland.

Researchers are studying similar therapies in hopes of curing genetic syndromes like sickle cell disease. And the stem cell agency is funding gene therapy research into potential treatments for HIV, brain cancer and Huntingtons disease, among others.

Gene therapy has been shown to work, the efficacy has been shown. And its safe, said Sohel Talib, a senior science officer at the state stem cell agency. The confidence has come. Now we have to follow it up.

JaCeon was born at a hospital in Las Cruces, N.M., and diagnosed with SCID just after birth as part of a standard newborn screening. He was flown to UCSF, one of a handful of facilities with expertise in SCID, when he was 3 weeks old. His great-aunt joined him about a month later, in November.

The immune disorder is commonly known as bubble baby disease, because until fairly recently kids born with it had to live in isolation, often in plastic bubbles in hospital rooms or their own homes to protect them from infections.

Babies born with SCID have a genetic mutation that leaves their immune system unable to develop disease-fighting cells. Without treatment, most will die within a year. Since the 1970s, some babies with SCID were cured with a bone-marrow transplant. But to be effective, a perfect match was required, almost always from a sibling, and only about a fifth of kids have such a match.

Ja'Ceon Golden is held by patient care assistant Grace Deng, as Deng bottle feeds Golden at UCSF Benioff Children's Hospital on Wednesday, March 8, 2017, in San Francisco, Calif. Golden, who is five months old, is diagnosed with severe combined immunodeficiency disease (SCID). He is a patient at UCSF, where he stays in a sterile room. The hospital is working on a new gene therapy treatment for SCID. Golden was brought from New Mexico for the experimental treatment.

Ja'Ceon Golden is held by patient care assistant Grace Deng, as...

The rest could undergo a bone marrow transplant from a partial match in JaCeons case, his great-aunt was one but even when that treatment was successful, kids were left with fragile immune systems that required constant maintenance with antibiotics and other boosts.

Gene therapy, though, may prove as effective as a bone marrow transplant from a perfect match.

The procedure starts with doctors harvesting stem cells from a babys own bone marrow, usually taken from the hip. In JaCeons case, his stem cells were sent in January to St. Jude in Memphis, where scientists are perfecting the gene-therapy delivery mechanism.

Sending away JaCeons stem cells was probably the most stressful time of my life, short of my own kids maybe being born, said Dr. Morton Cowan, the lead investigator of the UCSF trial, who has worked in SCID research for more than 30 years.

JaCeons stem cells were flown east over the first big weekend of major storms in California. Flights were being canceled around the clock, and doctors only had a window of about 36 hours to get the fresh cells to the labs in Memphis.

The trip was successful, but not without a hitch. After the cells were engineered and were being sent back to California, the material for a few heart-stopping hours got lost in the mail.

In a couple of months, Cowan said, he hopes to be able to do the gene-therapy delivery at UCSF labs, avoiding the travel headaches.

For now, that still happens at St. Jude. Doctors used a virus in fact, HIV, the virus that causes AIDS to deliver the gene therapy to JaCeons stem cells. The virus is neutered, with all of the disease-causing pieces inside removed.

Whats left is a missile-like shell designed to infiltrate a cell and deliver whatever payload doctors have inserted inside in this case, a healthy gene that will restore the stem cells ability to build normal immune cells.

Back in San Francisco, the cells were infused into JaCeon via a port in his chest. Because theyre his own cells, there was no fear his body would reject them.

He did have to undergo mild chemotherapy to kill off some of his own bone marrow and make room for the re-engineered stem cells to roost, but UCSF has been developing a technique for limiting the dosage of chemotherapy given in gene therapy procedures.

JaCeon suffered no obvious side effects from either the stem cell infusion or the chemotherapy drugs, doctors said.

Hes just thriving. Hes just hes great, Cowan said. He added, We cant open the Champagne just yet, but early tests show the new gene is active, and JaCeon has had an uptick of certain immune cells.

The infusion procedure took just 20 minutes, and JaCeon slept through it, but it felt momentous nonetheless.

It had been difficult to decide to enroll JaCeon in the trial, Hawkins said. Since she was a partial match for a bone marrow transplant, she had the option of giving him the traditional and well-tested therapy.

Shed said to his doctors, So youre telling me hes a guinea pig? They told her, she recalls, If it works, he can open the door for other kids.

That night, as Hawkins slept on the decision, I kept waking up, waking up, all night long, she said. If there was a possibility he could save someone else ... she added, and then broke off in tears.

She spends about six hours with JaCeon every day, beginning each morning with a bath in sterile water, brought by nurses in special tubs. Shes constantly wiping down his toys, clothes, bedding and stuffed animals.

Ive changed a lot of diapers in my time, but this is way more complicated than with other kids, Hawkins said, demonstrating the multistep process she uses to prevent diaper rash.

Im not going to say its been easy, she said. But hes doing fine. I wouldnt have it any other way.

Erin Allday is a San Francisco Chronicle staff writer. Email: eallday@sfchronicle.com

Twitter: @erinallday

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Amid advances in gene therapy, 'bubble baby' in SF gains hope - San Francisco Chronicle

Pfizer scopes out sites for gene therapy plant in North Carolina – BioPharma-Reporter.com

Pfizer has confirmed it assessing potential sites in North Carolina for a gene therapy production plant.

Reports in the US press suggested Pfizer is considering either expanding its existing facility in Sanford, North Carolina or building the plant at a site nearby.

Kim Bencker, head of communications at Pfizer Global supply, told us in an emailed statement We recently announced that were moving forward with scoping potential sites in Sanford for our new gene therapy site.

She added: This work is still in the preliminary stages and we arent able to share additional detail at this time.

The move follows a little over a year after the US drug manufacturer acquired Bamboo, a North Carolina-based gene therapy developer.

The deal included a recombinant Adeno-Associated Virus (rAAV) vector design and production technology, a Phase I candidate for Giant Axonal Neuropathy and a preclinical programme targeting Duchenne Muscular Dystrophy (DMD).

Pfizer also gained a 11,000sq ft gene therapy manufacturing facility in Chapel Hill that Bamboo bought from the University of North Carolina in 2016.

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Pfizer scopes out sites for gene therapy plant in North Carolina - BioPharma-Reporter.com

US Government Issues NASA Demand, ‘Get Humans to Mars By 2033’ – Futurism

A Mandate For Humanity

Both chambers of Congress just passed the NASA Authorization Act of 2017. With this transformative development, the space agency got a lot more than just$19.508 billion in funding. They also got a very clear mandate: Get humanity to Mars.

To be clear, Mars has been in the works for some time; however, the 2017 Actplaces astrong emphasis on this goal, making it the focal point of NASAs long-term plans. In the document, congress asserts that the space agency is to get humans near or on the surface of Mars in the 2030s. Opposition to the bill from the administration isnt expected, so its more than likely to be passed into law by the presidency.

In order to get to Mars by the 2030s, Congress is asking NASA to develop an initial human exploration roadmap that must be submitted before December 1, 2017.

The bill outlines the necessity of this roadmap, stating: It is the sense of Congress that expanding human presence beyond low-Earth orbit and advancing toward human missions to Mars in the 2030s requires early strategic planning and timely decisions to be made in the near-term on the necessary courses of action for commitments to achieve short-term and long-term goals and objectives.

To that end, the 2017Act states that this plan should outline clear goals that are a bit closer to home, instead of just making a grand leap to the Red Planet all at once.The document states, A human exploration roadmap should begin with low-Earth orbit, then address in greater detail progress beyond low-Earth orbit to cis-lunar space, and then address future missions aimed at human arrival and activities near and then on the surface of Mars.

Speaking of the planned stages, NASA already has a basic outline: The human exploration of Mars crosses three thresholds, each with increasing challenges as humans move farther from Earth: Earth Reliant [now until the mid-2020s], the Proving Ground [2018-2030], and Earth Independent [now to 2030s and beyond].

You can see a full breakdown of each of these stages at this linkand a very basic breakdown of the stages in the NASA image below:

With these planned phases, NASA should be able to easily provide Congress with the roadmap that its asking for.

Through this new NASA Authorization Act, Congress affirms that Mars is the appropriate long-term goal for the human space flight program, and it is likely that the Moon will be a stop over in 2020, if the current administrations planspush forward.

Recently, much of the news covering missions to Mars involved private space companies, most notably, SpaceX and foreign space agencies including China and the UAE.

According to SpaceX CEO Elon Musk, the company will create a permanentMartian settlement. To that end, Musks plan includes the launch of the unmanned Red Dragon spacecraft by 2018, then sending a new and reusable rocket by 2022 (which will be powered by the just recently tested Raptor rocket), and eventually launching humans to Mars after thathopefully landing by 2025.However, much of the details still need to be fleshed out.

Regardless, Musk has made it clear that he thinks such a colonization project will ultimately save the human race. And as this directive by congress reveals, the U.S. government agrees. See SpaceXs plans in this video:

To say, however, that NASA has been sitting idly by would be inaccurate. The space agency has been on a journey to Mars for some time.

So, what has NASA been up to in relation to the Red Planet? The agency already has a host of rovers currently on Mars. One, the Curiosity rover, has made much headway in helping us better understand how much water did (and maybe still does) exist on Mars.Another rover is planned for 2020. This Mars 2020 rover will gather and study data on the availability of resources, such as oxygen, on Mars.

In this respect, Sending rovers isone of the first steps in getting people to Mars.

Ultimately, in the end, getting humans to Mars isnt some empty obsession. Its a worthwhile endeavorone that has the potential to inspire generations in the same manner that the Apollo missions (and Moon landing) did. For many, getting to Mars would be the highest point of human exploration they would ever witness. Think of what New Horizons arrival at Pluto felt like, and now multiply that by about 100.

Already, Mars rover missions are accelerating innovation and research exponentially, so think of all the things that we could learn once were actually there. It is a bold new era in the final frontier.

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US Government Issues NASA Demand, 'Get Humans to Mars By 2033' - Futurism