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With an evening rocket launch, NASA hopes to color the skies red and green – Washington Post

Posted on June 14, 2017 by Danzig

June 14 at 3:49 PM

A highflying science experiment may color the skies with bluish-green and red clouds Thursday evening, as NASA seeks to learn more about charged particles at the upper part of Earths atmosphere.

A small rocket carrying 10 canisters, each about the size of a soda can, is scheduled to lift off from Wallops Island, Virginia, shortly after 9 p.m. About five minutes after launch, the canisters will release colorful vapors that will gather into artificial clouds potentially visible from New York to North Carolina.

The bright colors are caused by sunlight interacting with chemicals, including barium and strontium, and pose no harm to observers on the ground, NASA said.

The flight had been planned for May 31 but was delayed because of bad weather.

Although the flight will last about eight minutes, the colorful clouds could linger for 20 minutes, depending on the weather. NASA will track the clouds so scientists can learn more about the ionosphere, a layer at the top of the atmosphere where particles shoot out into space.

Reuters

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With an evening rocket launch, NASA hopes to color the skies red and green - Washington Post

Tiny Organisms Turn the Black Sea Turquoise in Amazing NASA Earth Photo – Space.com

Posted on June 14, 2017 by Danzig

Phytoplankton swirl in the Black Sea in this image from NASA's Aqua satellite.

Turquoise swirls in the Black Sea caused by phytoplankton carried on local water currents shine brightly in a new image from NASA's Aqua satellite.

Phytoplankton are tiny organisms that feed on sunlight and dissolved nutrients. The image shows the rivers Danube and Dnieper bringing these nutrients out to the Black Sea, where the phytoplankton feed on them, NASA officials said in a statement. In turn, these small organisms are eaten by larger animals such as fish and shellfish. [Earth from Space: More Amazing Photos]

In the Black Sea in particular, a type of phytoplankton community called coccolithophores are visible from afar because of the white calcium carbonate plates that shield their bodies, the statement said. The white is easily visible from space and appears like milk in the water. Diatoms, on the other hand another type of phytoplankton found in the Black Sea can make the water look somewhat darker.

In the statement, NASA said the reflectivity from phytoplankton in the Black Sea appears consistent with that of previous years. If the phytoplankton blooms are too large, this can lead to eutrophication, when oxygen is lost from the water and kills marine life.

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Tiny Organisms Turn the Black Sea Turquoise in Amazing NASA Earth Photo - Space.com

It’s fake! NASA never said the Earth will go dark for 15 days in November 2017 – PolitiFact (blog)

Posted on June 14, 2017 by Danzig

A persistent fake news story that claimed the Earth would be plunged into darkness after some kind of space event has been circulating for years.

A long-lived claim that NASA is warning the planet will be covered in darkness for more than two straight weeks continued to live on across the Internet but is completely made up.

A June 2, 2017, post on NewsForMeToday.com said that the Earth will go dark later this year with the headline, "NASA confirms Earth will experience 15 days of darkness In November 2017." Facebook users flagged the article as possibly being fabricated, as part of the social media sites efforts to identify fake news stories.

"NASA confirms whats been circling the web recently our planet Earth will experience total darkness for 15 days in November 2017 starting from November 15 to November 29," the post read. Specifically, the event "will start on November 15 at 3:00 am and will most likely last until November 30, 4:45 pm."

The post also quotes NASA administrator Charles Bolden as saying the so-called "blackout event" will raise the Earths temperature up to 8 degrees, but should have no lasting effects. "This event would be similar to what Alaskans experience in the winter," Bolden is quoted. For the record, Bolden resigned on Jan. 20, 2017.

There also was something in there about the alignment of Venus and Jupiter and a hydrogen explosion in space, but that doesnt matter, because the story is a persistent Internet concoction that isnt true.

The NewsForMeToday.com post doesnt link to any official source, a sure warning sign of an unreliable news report, but does cite a Jan. 12, 2017, post on ReflectionofMind.org.

That site, in turn, links back to a now-defunct page on GlobalRevolutionNetwork.com, which the Internet Archive told us was originally dated Oct. 24, 2016, and warned of the event happening in November of that year.

This unfounded rumor goes back to at least 2015, and has been posted time and again. Dates and details may change (one version said a solar storm would darken the Earth for six days in December), but none of them were correct.

We couldnt find any evidence of NASA making such an announcement, of course. We contacted NASA about the possibility an inky fortnight of celestial shenanigans, but didnt immediately hear back.

The fake story about Earth going dark has been around for some time, but its time we bring this hoax to light.

We rate it Pants On Fire!

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It's fake! NASA never said the Earth will go dark for 15 days in November 2017 - PolitiFact (blog)

Global Nanotechnology and Nanomaterials Market, 2027 – Applications, Producers, Product Developers and Products … – PR Newswire (press release)

Posted on June 14, 2017 by Danzig

"The Global Market for Nanotechnology and Nanomaterials 2010-2027" is the most comprehensive assessment of the opportunities afforded by these remarkable technologies and materials.

We are facing unprecedented global challenges such as the depletion of natural resources and climate change, pollution, scarcity of clean water, providing food and energy to a growing world population and poverty. These problems are directly linked to current technologies for producing energy and manufacturing products.

The exploitation of nanotechnology and nanomaterials is the key development that can significantly address these global problems by changing both the products and the means of their production and addressing pressing market needs in security, communications and electronics.

Contents include:

Key Topics Covered:

1 Research Methodology 1.1 Nanomaterials Market Rating System 1.2 Commercial Nanotechnology Impact Rating System 1.3 Market Challenges Rating System

2 Introduction 2.1 Aims and objectives of the study 2.2 Market definition 2.3 Categorization

3 Executive Summary

4 Nanomaterials Regulations 4.1 Europe 4.2 United States 4.3 Asia

5 Global Funding And Policy 5.1 United States 5.2 Japan 5.3 China 5.4 South Korea 5.5 Taiwan 5.6 Germany 5.7 European Union

6 Patenting

7 The Global Market For Nanomaterials 7.1 Aluminium Oxide Nanoparticles 7.2 Antimony Tin Oxide Nanoparticles 7.3 Bismuth Oxide Nanoparticles 7.4 Carbon Nanotubes 7.5 Cerium Oxide Nanoparticles 7.6 Cobalt Oxide Nanoparticles 7.7 Copper Oxide Nanoparticles 7.8 Dendrimers 7.9 Fullerenes 7.10 Gold Nanoparticles 7.11 Graphene 7.12 Iron Oxide Nanoparticles 7.13 Magnesium Oxide Nanoparticles 7.14 Manganese Oxide Nanoparticles 7.15 Nanocellulose 7.16 Nanoclays 7.17 Nanodiamonds 7.18 Nanofibers 7.19 Nanosilver 7.20 Nanowires 7.21 Nickel Nanoparticles 7.22 Quantum Dots 7.23 Silicon Oxide Nanoparticles 7.24 Titanium Dioxide Nanoparticles 7.25 Zinc Oxide Nanoparticles 7.26 Zirconium Oxide Nanoparticles 7.27 Other Nanomaterials 7.28 Other 2D Materials

8 Markets For Nanomaterials 8.1 Adhesives 8.2 Aerospace And Aviation 8.3 Automotive 8.4 Batteries 8.5 Biomedicine And Healthcare 8.6 Composites 8.7 Construction, Building Protection And Architectural Exterior Coatings 8.8 Cosmetics And Sunscreens 8.9 Electronics And Photonics 8.10 Filtration And Environmental Remediation 8.11 Food And Agriculture 8.12 Fuel Cells And Hydrogen Storage 8.13 Household Care And Sanitary 8.14 Lighting And UVC 8.15 Lubricants 8.16 Marine 8.17 Oil & Gas Exploration 8.18 Packaging 8.19 Security And Defence 8.20 Sensors 8.21 Solar 8.22 Supercapacitors 8.23 Textiles & Apparel 8.24 Tools & Manufacturing 8.25 3D Printing 8.26 Other Markets

For more information about this report visit https://www.researchandmarkets.com/research/3ztpgq/the_global_market

Media Contact:

Research and Markets Laura Wood, Senior Manager press@researchandmarkets.com

For E.S.T Office Hours Call +1-917-300-0470 For U.S./CAN Toll Free Call +1-800-526-8630 For GMT Office Hours Call +353-1-416-8900

U.S. Fax: 646-607-1907 Fax (outside U.S.): +353-1-481-1716

To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/global-nanotechnology-and-nanomaterials-market-2027---applications-producers-product-developers-and-products---research-and-markets-300473965.html

SOURCE Research and Markets

http://www.researchandmarkets.com

Global Market for Nanotechnology and Nanomaterials 2010-2027 – Research and Markets – Business Wire (press release)

Posted on June 14, 2017 by Danzig

DUBLIN--(BUSINESS WIRE)--Research and Markets has announced the addition of the "The Global Market for Nanotechnology and Nanomaterials 2010-2027" report to their offering.

"The Global Market for Nanotechnology and Nanomaterials 2010-2027" is the most comprehensive assessment of the opportunities afforded by these remarkable technologies and materials.

Contents include:

Key Topics Covered:

1 Research Methodology

2 Introduction

3 Executive Summary

4 Nanomaterials Regulations

5 Global Funding And Policy

6 Patenting

7 The Global Market For Nanomaterials

8 Markets For Nanomaterials

9 References

For more information about this report visit https://www.researchandmarkets.com/research/qzp3vs/the_global_market

New blood test uses nanotechnology to predict prostate cancer – Drug Target Review

Posted on June 14, 2017 by Danzig

news

A new diagnostic will allow men to bypass painful biopsies to test for aggressive prostate cancer.

The test, developed by Alberta scientists, incorporates a unique nanotechnology platform to make the diagnostic using only a single drop of blood, and is significantly more accurate than current screening methods.

The Extracellular Vesicle Fingerprint Predictive Score (EV-FPS) test uses machine learning to combine information from millions of cancer cell nanoparticles in the blood to recognise the unique fingerprint of aggressive prostate cancer.

The diagnostic, developed by members of the Alberta Prostate Cancer Research Initiative (APCaRI), was evaluated in a group of 377 Albertan men who were referred to their urologist with suspected prostate cancer. It was found that EV-FPS correctly identified men with aggressive prostate cancer 40% more accurately than the most common test Prostate-Specific Antigen (PSA) blood test in wide use today.

Higher sensitivity means that our test will miss fewer aggressive cancers, said John Lewis, the Alberta Cancer Foundations Frank and Carla Sojonky Chair of Prostate Cancer Research at the University of Alberta. For this kind of test you want the sensitivity to be as high as possible because you dont want to miss a single cancer that should be treated.

According to the team, current tests such as the PSA and digital rectal exam (DRE) often lead to unneeded biopsies. Lewis says more than 50 per cent of men who undergo biopsy do not have prostate cancer, yet suffer the pain and side effects of the procedure such as infection or sepsis. Less than 20% of men who receive a prostate biopsy are diagnosed with the aggressive form of prostate cancer that could most benefit from treatment.

Its estimated that successful implementation of the EV-FPS test could eventually eliminate up to 600-thousand unnecessary biopsies, 24-thousand hospitalisations and up to 50% of unnecessary treatments for prostate cancer each year in North America alone. Beyond cost savings to the health care system, the researchers say the diagnostic test will have a dramatic impact on the health care experience and quality of life for men and their families.

Compared to elevated total PSA alone, the EV-FPS test can more accurately predict the result of prostate biopsy in previously unscreened men, said Adrian Fairey, urologist at the Northern Alberta Urology Centre and member of APCaRI. This information can be used by clinicians to determine which men should be advised to undergo immediate prostate biopsy and which men should be advised to defer biopsy and continue prostate cancer screening.

The team plans to bring the test to market through university spin-off company Nanostics Inc, which was founded by John Lewis, Catalina Vasquez, Desmond Pink and Robert Paproski.

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New blood test uses nanotechnology to predict prostate cancer - Drug Target Review

3-in-1 device offers alternative to Moore’s law – Phys.Org

Posted on June 14, 2017 by Danzig

June 14, 2017 by Lisa Zyga feature Illustration of the reconfigurable device with three buried gates, which can be used to create n- or p-type regions in a single semiconductor flake. Credit: Dhakras et al. 2017 IOP Publishing Ltd

In the semiconductor industry, there is currently one main strategy for improving the speed and efficiency of devices: scale down the device dimensions in order to fit more transistors onto a computer chip, in accordance with Moore's law. However, the number of transistors on a computer chip cannot exponentially increase forever, and this is motivating researchers to look for other ways to improve semiconductor technologies.

In a new study published in Nanotechnology, a team of researchers at SUNY-Polytechnic Institute in Albany, New York, has suggested that combining multiple functions in a single semiconductor device can improve device functionality and reduce fabrication complexity, thereby providing an alternative to scaling down the device's dimensions as the only method to improve functionality.

To demonstrate, the researchers designed and fabricated a reconfigurable device that can morph into three fundamental semiconductor devices: a p-n diode (which functions as a rectifier, for converting alternating current to direct current), a MOSFET (for switching), and a bipolar junction transistor (or BJT, for current amplification).

"We are able to demonstrate the three most important semiconductor devices (p-n diode, MOSFET, and BJT) using a single reconfigurable device," coauthor Ji Ung Lee at the SUNY-Polytechnic Institute told Phys.org. "While these devices can be fabricated individually in modern semiconductor fabrication facilities, often requiring complex integration schemes if they are to be combined, we can form a single device that can perform the functions of all three devices."

The multifunctional device is made of two-dimensional tungsten diselenide (WSe2), a recently discovered transition metal dichalcogenide semiconductor. This class of materials is promising for electronics applications because the bandgap is tunable by controlling the thickness, and it is a direct bandgap in single layer form. The bandgap is one of the advantages of 2D transition metal dichalcogenides over graphene, which has zero bandgap.

In order to integrate multiple functions into a single device, the researchers developed a new doping technique. Since WSe2 is such a new material, until now there has been a lack of doping techniques. Through doping, the researchers could realize properties such as ambipolar conduction, which is the ability to conduct both electrons and holes under different conditions. The doping technique also means that all three of the functionalities are surface-conducting devices, which offers a single, straightforward way of evaluating their performance.

"Instead of using traditional semiconductor fabrication techniques that can only form fixed devices, we use gates to dope," Lee said. "These gates can dynamically change which carriers (electrons or holes) flow through the semiconductor. This ability to change allows the reconfigurable device to perform multiple functions.

"In addition to implementing these devices, the reconfigurable device can potentially implement certain logic functions more compactly and efficiently. This is because adding gates, as we have done, can save overall area and enable more efficient computing."

In the future, the researchers plan to further investigate the applications of these multifunctional devices.

"We hope to build complex computer circuits with fewer device elements than those using the current semiconductor fabrication process," Lee said. "This will demonstrate the scalability of our device for the post-CMOS era."

Explore further: Team engineers oxide semiconductor just single atom thick

More information: Prathamesh Dhakras, Pratik Agnihotri, and Ji Ung Lee. "Three fundamental devices in one: a reconfigurable multifunctional device in two-dimensional WSe2." Nanotechnology. DOI: 10.1088/1361-6528/aa7350

Journal reference: Nanotechnology

2017 Phys.org

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What's next?

Maybe the construct of intent. The how and why influence enlists underlying capabilities.

Nope. Moore's law isn't about speed or efficiency, but about the number of transistors at the lowest price point per transistor. Scaling down doesn't necessarily bring cost advantges, so simply fitting more transistors per square inch doesn't follow Moore's law.

Again they get it wrong.

Not sure I see the point of this. In situations where Moore's law matters (high density memory/processor logic), one generally has massive arrays of the same kind of component and they are usually dedicated, not programmable. If these things could productively do useful things simultaneously, that would be something, but they are one function at a time. Perhaps one could make some sort of Read Only Memory/FLASH-like memory out of them by programming locations to be a transistor or diode, but there's unlikely to be a density gain by doing that. This could be a significant advance in programmable arrays, but I don't see it helping much for conventional memory and logic.

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3-in-1 device offers alternative to Moore's law - Phys.Org

MSU Gran Fondo funds promising skin cancer studies – MSUToday

Posted on June 14, 2017 by Danzig

MSUToday

MSU Gran Fondo funds promising skin cancer studies
MSUToday
To make a long story short, I wouldn't be working on this if it wasn't for the MSU Gran Fondo, said researcher Fredric Manfredsson, an assistant professor in the Department of Translational Science & Molecular Medicine. In its first four years, the ...

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MSU Gran Fondo funds promising skin cancer studies - MSUToday

Global symposium on ‘precision medicine in cancer’ to be held today – The Indian Express

Posted on June 14, 2017 by Danzig

By: Express News Service | Pune | Published:June 15, 2017 1:42 am

On Thursday, the first global symposium on Precision Medicine in Cancer evolving paradigms will get underway in the city. Experts from across the world will participate in the emerging field of precision medicine which is making a difference in treatment of some of the cancers.

Personome-Germany, an international molecular information company that helps oncologists to personalise cancer treatment options based on a patients genomic and biomarker signature, has set up a molecular genomics lab in Pune.

Dr Aniket Ausekar, molecular biologists, told The Indian Express that precision medicine is an approach to patient care that allows doctors to select treatments most likely to help patients based on a genetic understanding of their disease. At the conference the case of a 20-year-old youth from Saswad who had lung cancer that had spread to the liver and benefited from the precision medicine approach will be highlighted.

The youngster was economically disadvantaged and two years ago we tried to understand why he had this cancer. The biopsy was sent by the treating cancer surgeon Dr Minish Jain and after a series of tests we were able to identify a drug for the specific mutation of the cancer. One of the premier biopharmaceutical firms provided the drug free of cost and the youngster has recovered, Ausekar said.

The idea of precision medicine is not new, but recent advances in science and technology have helped speed up the pace of this area of research. When you are diagnosed with cancer, one usually receive the same treatment as others who have same type and stage of cancer. Scientists now understand that patients tumors have genetic changes that cause cancer to grow and spread, Dr Swapnil Karnik, oncohistopathologist and one of the founder director of Megavision Life Sciences Private limited.

Personome has tied up with Megavision Lifesciences and founder directors Dr Karnik and Dr Bhushan Khedkar to look at the genetic changes in cancer via DNA sequencing, genomic testing and molecular profiling. The main aim is to personalise cancer treatment options based on the patients genomic and biomarker signature. John Beeler-Christian Garbe and Josef Scheiber, among others, will deliver talks on the occasion.

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Global symposium on 'precision medicine in cancer' to be held today - The Indian Express

UTI treatment reduces E. coli, may offer alternative to antibiotics – Washington University School of Medicine in St. Louis

Posted on June 14, 2017 by Danzig

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Treatment with molecular decoy may lessen recurrent infections, mouse study shows

An E. coli bacterium (above, in gold) attaches to and invades cells lining the inner surface of the bladder. UTIs are among the most common infections, and they tend to recur. Researchers at Washington University School of Medicine in St. Louis have found a molecular decoy that reduces the number of UTI-causing gut bacteria. This compound potentially could lower the chance of repeat UTIs.

Urinary tract infections (UTIs) are among the most common infections, and they tend to come back again and again, even when treated. Most UTIs are caused by E. coli that live in the gut and spread to the urinary tract.

A new study from Washington University School of Medicine in St. Louis has found that a molecular decoy can target and reduce these UTI-causing bacteria in the gut. With a smaller pool of disease-causing bacteria in the gut, according to the researchers, the risk of having a UTI goes down.

The ultimate goal of our research is to help patients manage and prevent the common problem of recurrent urinary tract infections while at the same time helping to address the worldwide crisis of antimicrobial resistance, said Scott J. Hultgren, PhD, the Helen L. Stoever Professor of Molecular Microbiology and the studys senior author. This compound may provide a way to treat UTIs without the use of antibiotics.

The study is published June 14 in Nature.

Close to 100 million people worldwide acquire UTIs each year, and despite antibiotic treatment, about a quarter develop another such infection within six months. UTIs cause painful, burning urination and the frequent urge to urinate. In serious cases, the infection can spread to the kidneys and then the bloodstream, where it can become life-threatening.

Most UTIs are caused by E. coli that live harmlessly in the gut. However, when shed in the feces, the bacteria can spread to the opening of the urinary tract and up to the bladder, where they can cause problems. Conventional wisdom holds that UTIs recur frequently because bacterial populations from the gut are continually re-seeding the urinary tract with disease-causing bacteria.

Hultgren, graduate student Caitlin Spaulding, and colleagues reasoned that if they could reduce the number of dangerous E. coli in the gut, they could reduce the likelihood of developing a UTI and possibly prevent some recurrent infections.

First, the researchers identified genes that E. coli need to survive in the gut. One set of genes coded for a kind of pilus, a hairlike appendage on the surface of E. coli that allows the bacteria to stick to tissues, like molecular velcro. Without this pilus, the bacteria fail to thrive in the gut.

Earlier studies found that the identified pilus attaches to a sugar called mannose that is found on the surface of the bladder. Grabbing hold of mannose receptors on the bladder with the pilus allows the bacteria to avoid being swept away when a person urinates. Bacteria that lack this pilus are unable to cause UTIs in mice.

Previously, Hultgren and co-author, James W. Janetka, PhD, an associate professor of biochemistry and molecular biophysics at Washington University, chemically modified mannose to create a group of molecules, called mannosides, that are similar to mannose but changed in a way that the bacteria latch onto them more tightly with their pili. Unlike mannose receptors, though, these mannosides are not attached to the bladder wall, so bacteria that take hold of mannosides instead of mannose receptors are flushed out with urine.

Since the researchers found that this same pilus also allows the bacteria to bind in the gut, they reasoned that mannoside treatment could reduce the number of E. coli in the gut and perhaps prevent the spread of the bacteria to the bladder.

To test this idea, they introduced a disease-causing strain of E. coli into the bladders and guts of mice to mirror the pattern seen in people. In women with UTIs, the same bacteria that cause problems in the bladder usually also are found living in the gut.

The researchers gave the mice three oral doses of mannoside, and then measured the numbers of bacteria in the bladders and guts of the mice after the last dose of mannoside. They found that the disease-causing bacteria had been almost entirely eliminated from the bladder and reduced a hundredfold in the gut, from 100 million per sample to 1 million.

While we did not entirely eliminate this strain of bacteria from the gut, the results are still promising, said Spaulding, the papers first author. Reducing the number of disease-causing bacteria in the gut means there are fewer available to enter the urinary tract and cause a UTI.

The type of pilus the researchers studied is found in most strains of E. coli and some related bacterial species as well. In theory, mannoside treatment could cause other bacteria living in the gut with the same kind of pilus to be swept away, much as antibiotic treatment kills bystander bacteria along with the intended target. Eliminating harmless bacteria potentially opens up space in the gut for more dangerous microbes to grow. This can result in intestinal disorders, one of the known risks of broad antibiotic treatment.

In collaboration with co-author Jeffrey I. Gordon, MD, the Dr. Robert J. Glaser Distinguished University Professor at the School of Medicine, researchers measured the composition of the gut microbiome after mannoside treatment. They found that mannoside treatment had minimal effect on intestinal bacteria other than the ones that cause most UTIs. This is in stark contrast to the massive changes in the abundance of many microbial species seen after treatment with antibiotics.

This finding is exciting because weve developed a therapeutic that acts like a molecular scalpel, Spaulding said. It goes in and specifically cuts out the bacteria you want to get rid of, while leaving the remainder of the microbial community intact.

Furthermore, since mannoside is not an antibiotic, it potentially could be used to treat UTIs caused by antibiotic-resistant strains of bacteria, a growing problem. UTIs account for 9 percent of all antibiotics prescribed every year in the United States, so a therapy for UTI that avoids antibiotics could help curb the development and spread of antibiotic-resistant organisms.

Differences in anatomy and behavior between mice and women make mice a challenging model for testing whether reducing the bacterial load in the gut actually reduces the number of repeat UTIs. To answer that question, human studies are needed.

Hultgren has co-founded a company, Fimbrion Therapeutics, with Janetka and Thomas Mac Hooton, MD, of the University of Miami School of Medicine, to develop mannosides and other drugs as potential therapies for UTI. Fimbrion is working on identifying a promising candidate drug for clinical trials in humans.

Spaulding CN, Klein RD, Ruer S, Kau AL, Schreiber HL, Cusumano ZT, Dodson KW, Pinkner JS, Fremont DH, Janetka JW, Remaut H, Gordon JI, Hultgren SJ. Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist. Nature. June 14, 2017.

This work was supported by the National Institutes of Health (NIH), grant numbers K08AI113184, R01AI048689, RO1DK051406, P50DK064540, RC1DK086378, DK30292, RO1DK051406, and 1F31DK107057; the Research Foundation Flanders, grant number G030411N; the Hercules Foundation, grant number UABR/09/005; and the Flanders Institute for Biotechnology, grant number PRJ9.

Hultgren and Janetka are inventors on patent application US8937167, which covers the use of mannoside-based FimH ligand antagonists for the treatment of disease. The two have ownership interest in Fimbrion Therapeutics and may benefit if the company is successful in marketing mannosides.

Washington University School of Medicines 2,100 employed and volunteer faculty physicians also are the medical staff of Barnes-Jewish and St. Louis Childrens hospitals. The School of Medicine is one of the leading medical research, teaching and patient-care institutions in the nation, currently ranked seventh in the nation by U.S. News & World Report. Through its affiliations with Barnes-Jewish and St. Louis Childrens hospitals, the School of Medicine is linked to BJC HealthCare.

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UTI treatment reduces E. coli, may offer alternative to antibiotics - Washington University School of Medicine in St. Louis

Amber Rose stuns fans with graphic sex act upload – before yanking it offline – Daily Star

Posted on June 14, 2017 by Danzig

AMBER Rose just can't stop posting filth online.

INSTAGRAM

The former stripper shocked the world last weekend after posting a full frontal snap online.

Despite the X-rated snap being met with mass criticism, Kanye West's ex has turned the air blue again this time by sharing a sex act diagram with the world.

**PARIS HILTON OPENS UP ABOUT IBIZA RESIDENCY**

In the pic uploaded to Amber's Instagram account, a drawing of a woman can be seen apparently on her knees sucking suggestively on a man's fingers.

Amber Rose shows off her curves and boobs in the sexiest set of snaps.

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Amber Rose's seductive pictures

"Any woman that let you do this is nasty as f*** and will ruin your life," the post read.

"If you ever meet her, RUN![sic]"

Hinting at her own sexual preferences, Amber simply captioned the pic: "#LifeRuiner," along with a smirking emoji.

INSTAGRAM

Amber Rose knickerless snap goes viral as fans share their hilarious recreations.

1 / 22

Fans take on the Amber Rose Challenge

INSTAGRAM

"I need her lips," one user commented on the snap.

"Love it," another added.

A third continued: "Go on girl."

However, it seems Amber has finally lost her nerve as the post was quickly yanked offline.

TWITTER

The backtrack will no doubt go down a storm with Piers Morgan who has been very vocal in his opinion of Amber's NSFW pics.

"Put it away, luv. Thanks," he tweeted.

The Good Morning Britain host later added: "If famous men started posting naked photos to social media claiming it was to 'promote male empowerment', they'd be jailed."

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Amber Rose stuns fans with graphic sex act upload - before yanking it offline - Daily Star

Google Drive is making it way easier to backup your computer files – Mashable

Posted on June 14, 2017 by Danzig

Mashable

Google Drive is making it way easier to backup your computer files
Mashable
Google Drive is ready to be the answer to all your computer storage needs and not just the files you create and upload using its cloud-based services like Google Docs and Photos. The search giant just announced a new Backup and Sync tool, which will ...

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Google Drive is making it way easier to backup your computer files - Mashable

We Played Transference, Here’s What it’s Actually About – Twinfinite

Posted on June 14, 2017 by Danzig

During Ubisofts E3 conference,a creepy-looking VR title called Transference was shown.Its trailer heavily featured Elijah Wood and talked about how scientists had discovered a way to upload brain datasuch as trauma and emotions into a digital space. We were then told that Transferencerecreates one such test subjects personal experiences and allows players to relive them through the magic of virtual reality.Its certainly an interesting premise, but it didnt really tell us exactly what wed be doing. After some hands-on time with Transference at E3 2017, however, we can actually tell you a little bit more about it.

Now, before we go any further, no, Elijah Wood isnt your character, nor did he appear during our time with Transference. For those unaware, Wood co-founded Spectrevision, the studio working alongside Ubisoft to bring this experience to VR headsets. His appearance in the trailer was simply to present you with the studios findings into their work with brain data, almost breaking the fourth wall.

During the demo, we were dropped into a creepy old house at night. We were told we needed to explore the house and simply find objects that had been moved and put them back in their original places.In doing so, you uncover the story of The Walter Case a virtual memory recreation of a PTSD patients brain data.

From that, you can probably tell that Transference is a psychological thriller of sorts. Its first-person exploration gameplay feels reminiscent of Resident Evil 7s VHS tape missions, with a lingering, realistic threat, in an equally realistic setting. Exploring the house and grabbing these items may sound a little basic, but its the atmosphere, as well as a neat little mechanic in the form of what is essentially time travel-enabling light switches that really keeps things interesting.

During Transferences demo, whenever we turned the lights out, we transitioned between the house in 1992, and again in 2003. In doing so, we could explore previously unsafeareas, find different items, and then use the light switch again to bring it with us to the house in the other year.These unsafe areas are what make Transference so interesting.

Rather than just some ghoul jumping out and attacking you, youve got a chance of bumping into the PTSD patient whose memories youre currently exploring. Their unsettlingramblings and violent actions are uncomfortable to witness, and they feel incredibly unpredictable. Youll definitely want to sneak around them, as if they spot you, youre in for a whole world of trouble.

Having this whole experience in VR just enhanced the experience. I spent five minutes carrying a photoaround in my hand, nervously peering around doors to check the coast was clear. Every time I was spotted, I found myself physically jumping off my seat. It manages to make even the smallest things like a note saying Dont forget to turn out the light ominous and unsettling.

After just 15 minutes with Transference, its become my most anticipated VR title.Its such an interesting and novel concept that I cant wait to unravel more of the intriguing story that SpectreVision has crafted within this PTSD patients mind. While the game is playable on your TV on PC, PS4 and Xbox One, I implore you to play it on a VR headset if you can.

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We Played Transference, Here's What it's Actually About - Twinfinite

E3 2017: Sony Video Talks Future PSVR Upgrades: AI, Focus Variation And More – UploadVR

Posted on June 14, 2017 by Danzig

Just like any other VR headset, Sonys PlayStation VR (PSVR) leaves plenty of room for improvement, and the companys R&D division has a few ideas on where to take it on both a software and hardware level.

Dominic Mallinson, Senior Vice President of R&D at Sony Interactive Entertainment, spoke a little about the current areas of VR that the group is looking into in a video that ran before the companys E3 press conference yesterday. You can see it below, the clip starts at around 43:20.

As weve heard before, Sony seems very interested in artificial intelligence, and using it to create believable virtual characters.

Mallinson spoke about natural language understanding, which he compared to voice operated platforms like Apples Siri, Amazon Echo. Imagine you could use that to actually talk to game characters, to actually have a dialogue, he said.

Building on that, the companys also interested in affecting the virtual world around you with gaze tracking. Mallinson spoke about using the direction the player was looking to change the virtual world around them. You might stare at a character, for example, who might become uncomfortable after continued surveillance. Note his wording doesnt specifically say eye-tracking, which would give games more accurate info about where a user is looking, but would require an upgrade on the hardware front.

Mallinson isnt ruling out hardware upgrades though. He also spoke about VR displays, and the importance of integrating focus variation to simulate our real world vision.

Now the eye does this all the time, and you dont really think about it, Mallinson said. But in VR that doesnt happen today.

Indeed, when you put on a VR headset, everything in sight is perfectly in focus. It may not distract you you may not even realise it but this isnt natural.

What we want to do is we also want to bring that in so we have re-focusing in virtual reality, Mallinson added. He said that, in the future, he believes headsets will be able to deliver both focus variation and 3D images. That will give us the ultimate visual experience, he said.

Finally, Mallinson looked far into the future with a concept he said was almost in the realm of science fiction: brain wave interfaces. With tech that could read the most basic impulses in your brain theres a world of possibilites for VR.

This is all ideas, this is all the future, looking just over the horizon, Mallinard concluded. And maybe well see it, maybe we wont.

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Disparities of women in medicine and science to be explored in Brown conference – The Providence Journal

Posted on June 14, 2017 by Danzig

'Although medical schools graduate nearly equal numbers of women and men, there is still a paucity of women in leadership in academic medicine and the biomedical sciences,' says professor and dean Sharkey.

PROVIDENCE, R.I. The persisting disparities of women in science and medicine and what women in those fields can do to help change the equation will be discussed during a daylong conference Thursday sponsored by the Warren Alpert Medical School of Brown University.

"This conference is needed because although medical schools graduate nearly equal numbers of women and men, there is still a paucity of women in leadership in academic medicine and the biomedical sciences," Dr. Katherine M. Sharkey, Brown's assistant dean for Women in Medicine and Science, and an associate professor of medicine, psychiatry and human behavior, told The Journal.

"The 'trickle down' of this is that women physicians have fewer [federal] grants and publications and are paid more than $18,000 per year less than male physicians, even after controlling for lower-paying specialties and taking time off for maternity leave. Since most families are dual-career families nowadays, this hurts everyone, not just women."

That assessment is shared by keynote speaker Dr. Catherine DeAngelis, professor emerita of the Johns Hopkins University School of Medicine and the first female editor of the Journal of the American Medical Association, the nation's leading professional medical publication.

"I've learned that there are 4 essential characteristics of a good leader: Tough minded (NOT TOUGH), Tenacious, Thick-skinned and Tender-hearted," DeAngelis wrote in an email to The Journal.

"The latter two are expected of women, but when women display the first two, they are considered by many men to be difficult, nasty, arrogant and/or offensive. Hence, in addition to what Katie stated, only 22 percent of professors, sixteen percent of department directors and 15 percent of deans of medical schools are women. A great sense of humor helps a great deal."

The conference also features keynote remarks by Dr. Vanessa Britto, medical director of Wellesley College.

"These disparities impact healthcare," Sharkey said. "We are witnessing a national attack on women's health that I believe would be easier to combat if women comprised half of the medical school deans."

Said DeAngelis: "Women must work to be leaders using the '4 T characteristics' and mentor younger women to follow in their footsteps."

The professional development conference, "Achieving Equity in Medicine and Science an Era of Change,"runs from 8:15 a.m. to 3:30 p.m. Thursday at the Warren Alpert School, 222 Richmond St. Information at bit.ly/2soQ60A.

gwmiller@providencejournal.com

(401) 277-7380

On Twitter: @GWayneMiller

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Disparities of women in medicine and science to be explored in Brown conference - The Providence Journal

WHO classes HIV drug as an essential medicine – New Scientist

Posted on June 14, 2017 by Danzig

PrEP trials still to run in England

Justin Sullivan/Getty

THE World Health Organization has added anti-HIV drugs to its list of essential medicines, in a move that turns the spotlight on the UKs rationing of such drugs.

Pre-exposure prophylaxis, or PrEP, involves two drugs in a combined pill that significantly reduces the risk of catching HIV through unprotected sex. Public Health England (PHE) said it was too costly for the NHS even though it saves money in the long-term because fewer people need lifelong HIV treatment.

PHE said it would begin a 10,000-person trial of the therapy early in the 2017 financial year, but it still hasnt started.

The WHOs list of essential medicines should help countries prioritise the provision of vital drugs. Several other countries, such as the US, provide PrEP. Scotland and Wales have recently said they will supply it too.

In England, gay men tend to buy cheap generics online, through websites such as I WantPrEP Now, which works with NHS doctors to check the quality of the medicines.

This article appeared in print under the headline Essential HIV meds

New AMA president: Physicians must lead to reshape medicine – American Medical Association (blog)

Posted on June 14, 2017 by Danzig

Physicians are obliged to show true leadership by modeling the right behavior, working together, developing consensus-based solutions, drawing on the skills of each health care team member, and demonstrating integrity and respect in their interactions, the AMAs incoming president said in his inaugural speech during the 2017 AMA Annual Meeting in Chicago.

These obligations are especially heightened during a time when many patients access to health care is threatened by the uncertainties of health-system reform, said David O. Barbe, MD, MHA, the new AMA president, and the 172nd in the Associations history. He is a board-certified family physician from Mountain Grove, Missouri, a town of less than 5,000 people where the median annual household income of $28,000 is just a little more than half the state-wide average of $50,000.

There are three areas in which physicians role as leaders is especially critical, Dr. Barbe said. In advocating for health reform in todays political environment, in describing and shaping the future of health care, and in mentoring those who will one day follow us in this profession.

The call for integrity and respectful collaboration stands in stark contrast to the partisan divide that has befallen conversation about health-system reform in the nations capital, he said. That division struck during the debate seven years ago and it is happening again today, Dr. Barbe said.

There are some factions in Washington that both then and now are saying not only no, but Hell no to working togethereven on some of the most basic principles of access, availability and affordability, Dr. Barbe said.

I submit to you that that might be good theater, but it is not good policy. Its not good politics and it is definitely not good leadership, he said. Good leadership is constructive, consensus-building and principled.

Dr. Barbe is in a position to know about such qualities. He began his career in a solo, independent practice 34 years ago and continues in that practice today. He also serves as vice president, regional operations, for Mercy health system with responsibility for five hospitals, 90 clinics and more than 200 physicians and advanced practitioners.

Every day, Dr. Barbe noted, he sees patients who need tests or treatments, who are still uninsured or havent met their deductibles, and due to this, they often delay necessary care.

Because of these patients, I see firsthand, every day, why the AMAs unwavering goal of affordable health insurance coverage for all is worth fighting for, he said. Keeping this issue front and center is critical as we debate health system reform againand again and again.

Dr. Barbe noted the AMAs core health reform principlepart of the Associations comprehensive visionthat no one who has gained insurance coverage in recent years should lose it as a result of new health-system reform legislation. But, he explained, that principle is flexible and practical in that we are willing to consider options for better, more cost-effective ways to cover the uninsured than we are doing now.

Physicians should not allow themselves to be corrupted or co-opted by the hyper-partisan political climate, Dr. Barbe added. We, as physicians, and as a profession, are better than that.As physician leaders, we bear greater responsibility within our profession and society.We must continue to put our patients before politics.

In shaping the future of health care, Dr. Barbe said the AMA is leading the way by:

By helping physicians with better preparation and better tools, they can deliver better care, Dr. Barbe said.

Taken together, he concluded, this is the way we will restore the joy to the practice of medicine.

Read more news coverage from the 2017 AMA Annual Meeting.

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New AMA president: Physicians must lead to reshape medicine - American Medical Association (blog)

A precision medicine fight is brewing between clinicians, public health – Healthcare IT News

Posted on June 14, 2017 by Danzig

BOSTON -- Trying to apply new precision medicine methodologies when there are no precedents can be scary for physicians and patients alike. And the practice of genome sequencing and population screening are on the verge of getting more contentious.

Genomic sequencing is an artisanal process if you want to be at the standard of care, said Robert Green, MD, a medical geneticist and physician-scientist at Brigham and Womens Hospital and Harvard Medical School. Genomic medicine is outside, knocking on the door trying to get in.

Green pointed to the BabySeq Project, which offers free genome sequencing for newborns, and said that 93 percent of parents turn that down as a current example of how hard it can be to convince people to share their data and participate in precision medicine programs.

[Also:Why legal challenges could slow down precision medicine]

In the near term I think we will have a lot of skirmishes and maybe even a war about population screening, pitting clinical perspective of those who want to know everything against the public health perspective which says be careful what you screen for because you might have unforeseen consequences and costs downstream, Green said.

Its a matter of trust, but Vik Bakhru, chief operating officer of ConsejoSano, said precision medicine trust is only in its early stages.

How do we inspire trust that the data is actionable and they can benefit from treatments out there? Bakhru said.

One way is to educate prospective participants about the upsides. Penn Medicine, for instance, has changed the treatment plans on 80 percent of the patient it has sequenced, according to associate vice president Brian Wells.

Green said there are three big questions that have to be answered to earn that trust: Is genetic information toxic? Will participants and their providers misunderstand genomic information? Will benefits outweigh harms and justify the cost?

Its not that doctors dont know what to do with or how to interpret the data, and it isnt even about the cost, Green said. Instead, its the lack of clinical utility data thats the major obstacle of genomic medicine. Without that, precision medicine proponents cant get insurance companies to reimburse for genomic sequencing so its not a standard of care.

Green said that answering those questions and overcoming that clinical data utility obstacle will happen because the benefits ultimately outweigh the risk. Early evidence, in fact, suggests that using genome sequencing can pinpoint molecular diagnoses in about 25 percent of cases.

This is well established in the armamentarium of genomics, Green said. We have to work decision support into the process but we are going to get there.

Twitter:SullyHIT Email the writer: tom.sullivan@himssmedia.com

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Quest to spread precision medicine to oncologists nationwide … – Healthcare IT News

Posted on June 14, 2017 by Danzig

In April, the Office of the National Coordinator said American healthcare is at the dawn of a new age: The Precision Medicine Initiative will usher in an era of individualized healthcare, ONC chief scientist Teresa Zayas Caban and ONC health scientist administrator Kevin Chaney said.

Laboratory giant Quest Diagnostics is hopping onto precision medicine early, and with a new acquisition hopes to expand precision medicine services to community oncologists nationwide.

[Also:The dawn of precision medicine has begun, ONC says]

Quest will form what it labels a precision oncology center of excellence through its acquisition of two Texas laboratory businesses with plans to serve oncologists across the country. Quest will acquire Med Fusion and Clear Point to create a base in the southwestern United States for providing precision medicine diagnostics to aid cancer treatment and care.

The acquisition involves preferred provider relationships for Quest with Baylor Scott & White Health, McKessons The US Oncology Network, Texas Oncology, and Pathologists Bio-Medical Laboratories.

The development of standardized, evidence-based services for guiding treatment decisions within electronic health records and care plan workflows is expected to be one of the outcomes of the precision oncology center effort. Quest expects to be able to offer versions of these services, once developed, to other providers in the United States with the goal to advance better cancer outcomes, Quest said.

[Also:Widespread precision medicine is still years away, experts say]

Quest will become a preferred provider of advanced oncology diagnostics for The US Oncology Network, including Texas Oncology. The network is the largest of its kind, consisting of more than 400 locations across the United States and more than 1,400 independent, community-based physicians, Quest said. The advanced diagnostics Quest will provide include genomic and pathology testing, such as tumor sequencing, typically used by oncologists to select and monitor treatment and predict disease progression, Quest explained.

In addition, Quest will be a preferred provider of a range of inpatient and outpatient diagnostic services for 12 hospitals of Baylor Scott & White Health in North Texas. Quest will provide these services from the center of excellence site in Lewisville, Texas, upon close of the acquisition. Quest and Pathologists Bio-Medical Laboratories also will have a preferred provider relationship for several services.

Nearly 1.7 million people are expected to be diagnosed with cancer in the United States in 2017, according to the American Cancer Society.

Precision medicine is changing the way we treat cancer and giving new hope to people living with the disease, but too often advanced diagnostics that facilitate the best possible care are out of reach of community oncologists and their patients, said Steve Rusckowski, chairman, president and CEO of Quest Diagnostics. By partnering with McKesson Specialty Health and The US Oncology Network, we will make Quests state-of-the-art genomic analysis readily available to community oncologists everywhere.

The acquisition is expected to be completed in the third quarter of calendar year 2017, subject to customary closing conditions.

The center will complement Quests existing centers of excellence in San Juan Capistrano and Valencia, California; Chantilly, Virginia; and Marlborough, Massachusetts. These laboratories generally specialize in advanced diagnostic services for marquee health systems and specialty physicians. In Texas, Quest Diagnostics also operates full-service laboratories in Irving and Houston.

Twitter:@SiwickiHealthIT Email the writer: bill.siwicki@himssmedia.com

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Quest to spread precision medicine to oncologists nationwide ... - Healthcare IT News

Chinese Medicine is Using Donkey Skins to Boost Libidoand Africa’s Animals Are at Risk – Newsweek

Posted on June 14, 2017 by Danzig

Demand for a form of traditional Chinese medicine is putting the donkey population at risk in South Africa and other parts of the continent.

In recent years, the market in ejiaoa product made from boiled-down donkey skins mixed with herbs and other ingredientshas grown massively in China, putting millions of donkeys at risk of slaughter or poaching.

In South Africa, poor farmers who rely on donkeys as beasts of burden and modes of transport have reported having their animals stolen, only to later find their skinless carcasses.

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South Africas Society for the Prevention of Cruelty to Animals has confiscated more than 1,000 donkey hides en route to China in the past year, chief inspect Mpho Mokoena told Voice of America (VOA). Mokoena fears that the growing trade in donkey skins could signal the extinction of the animal in South Africa. In two years there wont be [any] donkeys in South Africa, she told VOA.

Donkey skins dry in the sun at a licensed specialized slaughterhouse in Baringo, Kenya, on February 28. The trade in donkey skins is legal in some countries, but is putting donkey populations in parts of Africa at risk. TONY KARUMBA/AFP/Getty

The slaughter of donkeys and trade in their skins is on an upward trend in other parts of Africa, too. A January report by U.K.-based charity the Donkey Sanctuary found that demand for donkeys in Africa has risen so much that, in the West African country of Burkina Faso, the cost of a single animal almost doubled from 60 ($76) in 2014 to 108 ($137) in 2016.

Read more: Take Two Herbs and Call Me in the Morning

The global donkey population stands at around 44 million, the vast majority of which are working animals, but the Donkey Sanctuary report estimated that global demand for donkey skins is between 4-10 million, with at least 1.8 million donkey skins being traded per year.

Four African countriesBurkina Faso, Mali, Niger and Senegalhave banned donkey exports, as well as Pakistan. The consumption of donkey meat is also considered haram (forbidden) in Islam, meaning that the slaughter of donkeys in many countries with large Muslim populations is frowned upon.

Donkeys are under threat largely due to the rise in popularity of ejiao, according to the report. In China, some believe that ejiao has various health benefits, from anti-aging properties to boosting sex drive, and it is even marketed as a gynecological treatment that can reduce reproductive diseases in women. Demand is so high that ejiao can sell for up to 300 ($382) per kilogram, according to the Donkey Sanctuary report.

Traditional medicine in China and other parts of East Asia is associated with the decline of other animal populations and wildlife agencies have said that wild rhinoceros could be wiped out within a decade as a result of increased poaching. Rhino horn can sell for up to $60,000 per kilogrammore valuable by weight than gold or diamondsdue to myths that it can solve a wide range of medical ailments, including cancer and hangovers.

Tiger bones are also reputed to be a remedy for arthritis in traditional medicine, while ivory from elephant tusks is also used in some medications, as well as being prized for ornamental purposes in China.

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Chinese Medicine is Using Donkey Skins to Boost Libidoand Africa's Animals Are at Risk - Newsweek

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