NASA Closes Out Its Asteroid Redirect Mission – Sky & Telescope

Following the release of the 2018 budget, the space agency has ordered an orderly closeout for the Asteroid Redirect program.

NASA's Asteroid Redirect Mission would have retrieved a boulder from the surface of an asteroid. NASA

After years of study, NASA announced recently that its plan to retrieve an asteroid and place it in lunar orbit, known as the Asteroid Redirect Mission (ARM), will be shut down due to lack of congressional support in the proposed FY2018 budget. The NASA ARM program director Michele Gates made the announcement on June 13th, during the recent meeting of the Small Bodies Assessment Group held at the Goddard Space Flight Center in Greenbelt, Maryland. The focus will now turn shutting down the program while salvaging key technologies and lessons learned for other possible future applications.

The agency remains committed to the next human missions to deep space, but we will not pursue the Asteroid Redirect Mission (ARM) with the Fiscal Year 2018 budget proposal, says Kathryn Hambleton (NASA). The ARM team is in the process of documenting its activities to ensure key knowledge from the mission concept is archived as part of an orderly closeout.

This artist's concept shows an astronaut examining the returned boulder while in lunar orbit. NASA

ARM was an ambitious plan from the start. First proposed in 2013, the project called for an automated rendezvous and capture of a small near-Earth asteroid, which would then be placed in orbit around the Moon. Astronauts would then rendezvous with the asteroid in lunar orbit, study the asteroid, and collect and return samples to Earth. NASA ARM would have relied on the new Orion crewed capsule and the new Space Launch System (SLS) heavy lift rocket, both still under development.

Politically, the mission had detractors from the start, and it failed to find support in Congress, even though the plan was often touted as a stepping stone between leaving low-Earth orbit and heading to Mars in the 2030s. From an engineering perspective, the plan plan was complex, requiring an automated spacecraft to retrieve an SUV-sized boulder from a larger asteroid moving slowly relative to Earth's orbital motion, a scenario that significantly limited the potential targets.

Our best look at Bennu, one of the asteroid candidates for the boulder retrieval concept of ARM. The image at right shows radar reflectivity as measured by Arecibo, with the radar beam shining from the top. At right is a reconstruction of Bennu's shape using those data. NASA / Arecibo

But even as the ARM mission closes out, research and development will still continue in some key areas. The solar electric propulsion system, initially envisioned to fly on the robotic segment of ARM, is still being developed for future deep-space use. And the search for near-Earth asteroids involving observatories worldwide will go on.

While our long-term Mars architecture is still in development, Hambleton says, we've recently unveiled a concept using SLS and Orion to build a deep space gateway and transport in cis-lunar space to help us prepare for human deep space missions, including Mars.

Changes expected from the president's budget request for NASA. AAAS

The end of NASA ARM is also part of a larger picture: a time of transition amid the new presidential administration. NASA overall actually makes out pretty well in the proposed FY2018 budget: $19.1 billion dollars, a 3% drop from the $19.7 billion budget of FY17, though still slightly above where NASA funding levels have stalled for the past decade. Planetary sciences was the big winner in the FY18 NASA budget, getting a proposed $1.9 billion dollars, the division's highest annual funding to date. This will support the Mars 2020 rover and the Mars InSight lander, as well as the Europa Clipper and Lucy and Psyche asteroid missions planned for the 2020s.

A lion's share of NASA's proposed budget will go towards continued support of the International Space Station, the James Webb Space Telescope (set to launch in late 2018), and development of the Orion capsule and the SLS, though the latter face significant cuts. The first flight of Orion aboard the SLS is slated for 2019 and will carry an uncrewed capsule around the Moon and back. NASA studied the idea of putting a crew on the first Orion/SLS flight but nixed the idea last month.

Along with NASA ARM, NASA's Earth sciences division will take a hit under the proposed budget, losing $170 million dollars for a nearly 9% drop from FY17 to FY18. This puts several crucial Earth observing missions, including the Orbiting Carbon Observatory (OCO-3) and the Deep Space Climate Observatory (DSCOVR), in jeopardy. However, 18 Earth-observing missions will remain in orbit, according to NASA acting administrator Robert Lightfoot.

NASA's Office of Education also faces closure with this budget, with just $37 million set aside for transitional and closing costs.

However, while some changes appear to be set, such as the ARM close-out, it's important to remember that the president's budget request often changes before it becomes signed into law later in the year. The Planetary Society offers their take on NASA's new budget here. To learn how the NASA budget comes about, watch this explanation from The Planetary Society's Casey Dreier:

When it comes to NASA funding, it's an uncertain time of crisis and opportunity. As ever, the phrase no bucks, no Buck Rogers applies. We're also now farther away from the end of the U.S. Space Shuttle program in 2011 than the first shuttle flight in 1981 was from the end of Apollo in 1975.

Perhaps, the lessons from NASA ARM will get paid forward, as U.S. astronauts once again venture out of low-Earth orbit in the next decade.

More:

NASA Closes Out Its Asteroid Redirect Mission - Sky & Telescope

NASA to broadcast epic solar eclipse this summer from Charleston. And the views should be fantastic – The State


The State
NASA to broadcast epic solar eclipse this summer from Charleston. And the views should be fantastic
The State
For the first time since 1970, the Lowcountry will witness a total solar eclipse, and NASA will share the experience with the world from Charleston's point of view. The space agency will livestream and broadcast the event from the College of Charleston ...
NASA Prepares for Aug. 21 Total Solar Eclipse with Live Coverage, Safety InformationSpace Daily
NASA releases images of solar eclipse from space, announces live broadcastThe Space Reporter

all 84 news articles »

Read the original post:

NASA to broadcast epic solar eclipse this summer from Charleston. And the views should be fantastic - The State

ESA to develop gravitational wave space mission with NASA support – Phys.Org

June 23, 2017 by Francis Reddy This illustration shows ESA's (the European Space Agency's) LISA observatory, a multi-spacecraft mission to study gravitational waves expected to launch in 2034. In the mission concept, LISA consists of three spacecraft in a triangular formation spanning millions of kilometers. Test masses in spacecraft on each arm of the formation will be linked together by lasers to detect passing gravitational waves. Credit: AEI/Milde Marketing/Exozet

ESA (the European Space Agency) has selected the Laser Interferometer Space Antenna (LISA) for its third large-class mission in the agency's Cosmic Vision science program. The three-spacecraft constellation is designed to study gravitational waves in space and is a concept long studied by both ESA and NASA.

ESA's Science Program Committee announced the selection at a meeting on June 20. The mission will now be designed, budgeted and proposed for adoption before construction begins. LISA is expected to launch in 2034. NASA will be a partner with ESA in the design, development, operations and data analysis of the mission.

Gravitational radiation was predicted a century ago by Albert Einstein's general theory of relativity. Massive accelerating objects such as merging black holes produce waves of energy that ripple through the fabric of space and time. Indirect proof of the existence of these waves came in 1978, when subtle changes observed in the motion of a pair of orbiting neutron stars showed energy was leaving the system in an amount matching predictions of energy carried away by gravitational waves.

In September 2015, these waves were first directly detected by the National Science Foundation's ground-based Laser Interferometer Gravitational-Wave Observatory (LIGO). The signal arose from the merger of two stellar-mass black holes located some 1.3 billion light-years away. Similar signals from other black hole mergers have since been detected.

Seismic, thermal and other noise sources limit LIGO to higher-frequency gravitational waves around 100 cycles per second (hertz). But finding signals from more powerful events, such as mergers of supermassive black holes in colliding galaxies, requires the ability to detect frequencies much lower than 1 hertz, a sensitivity level only possible from space.

LISA consists of three spacecraft separated by 1.6 million miles (2.5 million kilometers) in a triangular formation that follows Earth in its orbit around the sun. Each spacecraft carries test masses that are shielded in such a way that the only force they respond to is gravity. Lasers measure the distances to test masses in all three spacecraft. Tiny changes in the lengths of each two-spacecraft arm signals the passage of gravitational waves through the formation.

For example, LISA will be sensitive to gravitational waves produced by mergers of supermassive black holes, each with millions or more times the mass of the sun. It will also be able to detect gravitational waves emanating from binary systems containing neutron stars or black holes, causing their orbits to shrink. And LISA may detect a background of gravitational waves produced during the universe's earliest moments.

For decades, NASA has worked to develop many technologies needed for LISA, including measurement, micropropulsion and control systems, as well as support for the development of data analysis techniques.

For instance, the GRACE Follow-On mission, a U.S. and German collaboration to replace the aging GRACE satellites scheduled for launch late this year, will carry a laser measuring system that inherits some of the technologies originally developed for LISA. The mission's Laser Ranging Interferometer will track distance changes between the two satellites with unprecedented precision, providing the first demonstration of the technology in space.

In 2016, ESA's LISA Pathfinder successfully demonstrated key technologies needed to build LISA. Each of LISA's three spacecraft must gently fly around its test masses without disturbing them, a process called drag-free flight. In its first two months of operations, LISA Pathfinder demonstrated this process with a precision some five times better than its mission requirements and later reached the sensitivity needed for the full multi-spacecraft observatory. U.S. researchers collaborated on aspects of LISA Pathfinder for years, and the mission carries a NASA-supplied experiment called the ST7 Disturbance Reduction System, which is managed by NASA's Jet Propulsion Laboratory in Pasadena, California.

Explore further: Gravitational wave mission selected, planet-hunting mission moves forward

The LISA trio of satellites to detect gravitational waves from space has been selected as the third large-class mission in ESA's Science programme, while the Plato exoplanet hunter moves into development.

On December 3, 2015, the LISA Pathfinder mission blasted into space carrying the most stable spacecraft thruster system ever qualified for use in space. Developed by NASA JPL, the Space Technology 7 (ST-7) Disturbance Reduction ...

A key component of a future gravitational wave observatory passed a series of tests with flying colors, while coming closer to experiencing true free fall than any other human-made object ever has. At the heart of the experiment ...

Today, ESA has invited European scientists to propose concepts for the third large mission in its science programme, to study the gravitational Universe.

Black holes can be divided into three classes according to mass. On the low end are those with masses 10 times that of the sun. Examples are the two black holes whose merger generated the first gravitational wave to be detected, ...

LISA Pathfinder, a mission led by ESA (the European Space Agency) with contributions from NASA, has successfully demonstrated critical technologies needed to build a space-based observatory for detecting ripples in space-time ...

Long-term power cuts, destruction of electronic devices and increased cancer risk for aeroplane passengers are all potential effects of the Earth being hit by a powerful solar eruption.

A team of laboratory astrophysicists from Leiden University (the Netherlands) managed to make glycerol under conditions comparable to those in dark interstellar clouds. They allowed carbon monoxide ice to react with hydrogen ...

At any given moment, as many as 10 million wild jets of solar material burst from the sun's surface. They erupt as fast as 60 miles per second, and can reach lengths of 6,000 miles before collapsing. These are spicules, and ...

(Phys.org)A team of researchers form the U.S., Denmark and France has created a report regarding the creation and use of software meant to give exploratory robots in space more autonomy. In their paper published in the ...

For the first time in almost a century the United States is preparing for a coast-to-coast solar eclipse, a rare celestial event millions of Americans, with caution, will be able to observe.

(Phys.org)A pair of space scientists working at NASA's Jet Propulsion Laboratory at the California Institute of Technology has written a Focus piece for the journal Science Robotics. Steve Chien and Kiri Wagstaff suggest ...

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Read more:

ESA to develop gravitational wave space mission with NASA support - Phys.Org

Finding Neemo: Nasa goes from the bottom of the ocean to outer space – The Guardian

Living underwater has very similar dangers and parallels to living in a spacecraft: Nasas extreme environment mission operations (Neemo) expedition. Photograph: Karl Shreeves/Nasa

On Sunday a group of six astronauts, engineers and scientists submerged 19 metres to the bottom of an Atlantic Ocean reef to live underwater for Nasas extreme environment mission operations (Neemo) expedition.

Living underwater has very similar dangers and parallels to living in a spacecraft: closed-loop life support, pressurised habitat with incredibly efficient recycling systems, near weightless extra vehicular activities (EVAs, AKA spacewalks), a packed daily schedule, communications with mission control, the inability to return to Earth safely without a special vehicle and sufficient re-entry time to protect the crew and keep them alive. Each time they go outside, the habitat crew have to don full suits with personal oxygen tanks just like a spacewalk.

The only undersea laboratory in the world, Aquarius, off Florida, is adjacent to deep coral reefs and has been home to 50 astronauts so far. Crew cannot resurface without decompression as, after 24 hours underwater, they are totally saturated from nitrogen and inert gases, so rising up to normal air quickly would be fatal.

Living below the surface at 2.5 times the normal pressure of Earth allows for unprecedented science and exploration: regular divers can only stay up to 30 minutes at that depth, yet aquanauts can perform EVAs for up to eight hours a day. Astronauts train in giant swimming pools, so suiting up and performing hours of science missions outside the Aquarius in personal spacesuits with closed-loop oxygen is a pretty accurate analogue.

Day two of the mission we introduced a lunar voice delay of 1.7 seconds that, like for the Apollo astronauts, isnt too noticeable. Later however, we will have a time delay identical to Mars and move to text-based communications instead as its impractical to have a conversation with a pause of 20 minutes between talking and replying! At the end of the mission, crew will be brought back over 17 hours to normal Earth pressure so that the gases can escape their bodies safely and they can resurface to see the sun and feel the wind again. Just like living in space, astronaut-aquanauts miss the weather.

Topside mission control sees the mission director, capcom, planning, EVA and science rep backed up by a 24/7 watch desk inside and two science trailers in the carpark. The European Space Agency (ESA) deployed their new Lunar evacuation system assembly (Lesa), something that the Apollo missions were lacking. This brilliant feat of engineering allows a single person to secure and evacuate an incapacitated crew member on the moon and has been tested in the European astronaut centres neutral buoyancy facility. My day job is Eurocom for the International Space Station (ISS), working hundreds of different science experiments and systems engineering with the astronauts in their packed 12-hour workdays on orbit. ISS has five mission controls: Houston, Huntsville, Munich, Moscow and Tsukuba. At each mission control only one flight controller position can talk back to the astronauts when they call Earth, and frequently Europe replies with a distinctly Australian accent mine. After years of talking up to space, my voice now also travels down below the Atlantic Ocean.

Working underwater with extended daily dive times and living in the pressurised Aquarius habitat means heat is pulled from their bodies much faster and their metabolism needs to work very hard. As a result they need to eat a lot more compared to when theyre on Earth. Food needs to be preserved similar to space food, and some of it is real space food that isnt dehydrated military packs like the old days. European space food is produced in France and Italy and is genuinely tasty: tiramisu, risotto, pasta, quinoa, vegetables, soups, even gingerbread and sausage sizzles! Making space food really is rocket science it has to be nutritious, resistant to radiation, have a shelf life at room temperature of up to two years through natural preservatives and cannot produce any crumbs small pieces like that can cause major damage to station equipment.

And so this Aussie has found Neemo. The crew lived and trained together in the week before diving down to their new underwater home. Just like ISS missions where the crew train together for 2.5 years prior to Soyuz rocket launch, they grow to know each other well and become strong teammates before, during and after their mission. Space exploration truly transcends borders and rises above earthly politics to simply work together regardless of background, square away incredible science, research and technology development to benefit life on Earth and keep fellow crewmates safe while continuing long-lasting friendships.

You can watch live until 27 June here and find out more about Neemo here.

Read more:

Finding Neemo: Nasa goes from the bottom of the ocean to outer space - The Guardian

Stephen Hawking Proposes Nanotechnology Spacecraft to Reach ‘Second Earth’ in 20 years – HuffPost

Renowned physicist Stephen Hawking is proposing a nanotechnology spacecraft that can travel at a fifth of the speed of light. At that speed, it could reach the nearest star in 20 years and send back images of a suspected Second Earth within 5 years. That means if we launched it today, we would have our first look at an Earth-like planet within 25 years.

Hawking proposed a nano-spacecraft, termed Star Chip, at the Starmus Festival IV: Life And The Universe, Trondheim, Norway, June 18 23, 2017. Hawking told attendees that every time intelligent life evolves it annihilates itself with war, disease and weapons of mass destruction. He asserted this as the primary reason why advanced civilizations from another part of the Universe are not contacting Earth and the primary reason we need to leave the Earth. His advocates we colonize a Second Earth.

Scientific evidence appears to support Hawkings claim. The SETI Institute has been listening for evidence of extraterrestrial radio signals, a sign of advanced extraterrestrial life, since 1984. To date, their efforts have been futile. SETI claims, rightly, that the universe is vast, and they are listening to only small sectors, which is much like finding a needle in a haystack. Additional evidence that Hawking may be right about the destructive nature of intelligent life comes from experts surveyed at the 2008 Global Catastrophic Risk Conference at the University of Oxford, whose poll suggested a 19% chance of human extinction by the end of this century, citing the top four most probable causes:

1. Molecular nanotechnology weapons 5% probability

2. Super-intelligent AI 5% probability

3. Wars 4% probability

4. Engineered pandemic 2% probability

Hawking envisions the nano-spacecraft to be a tiny probe propelled on its journey by a laser beam from Earth, much the same way wind propels sailing vessels. Once it reaches its destination, Hawking asserts, Once there, the nano craft could image any planets discovered in the system, test for magnetic fields and organic molecules, and send the data back to Earth in another laser beam.

Would Hawkings nano-spacecraft work? Based on the research I performed during my career and in preparation for writing my latest book, Nanoweapons: A Growing Threat to Humanity (Potomac Books, 2017), I judge his concept is feasible. However, it would require significant engineering, as well as funding, to move from Hawkings concept to a working nano-spacecraft, likely billions of dollars and decades of work. However, in Nanoweapons, I described the latest development of bullets that contain nano-electronic guidance systems that allow the bullets to guide themselves, possibly to shoot an adversary hiding around a corner. Prototypes already exist.

Hawkings concept is compelling. Propelling a larger conventional spacecraft using a laser would not attain the near light speed necessary to reach a distant planet. Propelling it with rockets would also fall short. According to Einsteins theory of relativity, a large conventional spacecraft would require close to infinite energy to approach the speed of light. Almost certainly, Hawking proposed a nano-spacecraft for just that reason. Its mass would be small, perhaps measured in milligrams, similar to the weight of a typical household fly.

Hawkings concept represents a unique application of nanotechnology that could give humanity its first up-close look at an inhabitable planet. What might we see? Perhaps it already harbors advanced intelligent life that chose not to contact Earth, given our hostile nature toward each other. Perhaps it harbors primitive life similar to the beginning of life on Earth. We have no way of knowing without contact.

You may choose to laugh at Hawkings proposal. However, Hawking is one of the top scientists on Earth and well aware of advances in any branch of science he speaks about. I judge his concerns are well founded and his nano-spacecraft concept deserves serious consideration.

The Morning Email

Wake up to the day's most important news.

Read this article:

Stephen Hawking Proposes Nanotechnology Spacecraft to Reach 'Second Earth' in 20 years - HuffPost

Biofilm-Busting Enzymes May Rout Hospital-Acquired Infections – Genetic Engineering & Biotechnology News

We demonstrate that glycoside hydrolases derived from the opportunistic fungusAspergillus fumigatusand Gram-negative bacteriumPseudomonas aeruginosacan be exploited to disrupt preformed fungal biofilms and reduce virulence, wrote the authors of the PNAS article. Additionally, these glycoside hydrolases can be used to potentiate antifungal drugs by increasing their hyphal penetration, to protect human cells from fungal-induced injury, and attenuate virulence ofA. fumigatusin a mouse model of invasive aspergillosis.

This work is the result of a four-year collaboration between a McGill scientists led by Don Sheppard, M.D., and SickKids scientists led by Lynne Howell, Ph.D. "Rather than trying to develop new individual 'bullets' that target single microbes, explained Dr. Sheppard, we are attacking the biofilm that protects those microbes by literally tearing down the walls to expose the microbes living behind them. It's a completely new and novel strategy to tackle this issue.

"We made these enzymes into a biofilm-destroying machine that we can use outside the microbe where the sugar molecules are found," added co-first study author Brendan Snarr, a Ph.D. student in Dr. Sheppard's laboratory. "These enzymes chew away all of the sugar molecules in their path and don't stop until the matrix is destroyed."

"Previous attempts to deal with biofilms have had only limited success, mostly in preventing biofilm formation. These enzymes are the first strategy that has ever been effective in eradicating mature biofilms, and that work in mouse models of infection," noted Dr. Sheppard.

"When we took the enzymes from bacteria and applied them to the fungi, we found that they worked in the same way on the fungi biofilm; which was surprising," commented Dr. Howell. "What's key is that this approach could be a universal way of being able to leverage the microbes' own systems for degrading biofilms. This has bigger implications across many microbes, diseases, and infections."

"Over 70% of hospital-acquired infections are actually associated with biofilms, and we simply lack tools to treat them," stated Dr. Sheppard. According to both lead scientists, the potential of this novel therapy is enormous and they hope to commercialize it in the coming years.

Original post:

Biofilm-Busting Enzymes May Rout Hospital-Acquired Infections - Genetic Engineering & Biotechnology News

Use biofilm’s own enzymes to defeat its ‘armor’ – Futurity: Research News

Researchers have developed a way to use the same enzymes that help microbes create biofilms to keep biofilms from forming and even destroy them.

Biofilms are slimy, glue-like membranes that microbes, like bacteria and fungi, make in order to colonize surfaces. They can grow on animal and plant tissues, and even inside the human body on medical devices such as catheters, heart valves, or artificial hips.

Over 70 percent of hospital-acquired infections are actually associated with biofilms and we simply lack tools to treat them!

Biofilms protect microbes from the bodys immune system and increase their resistance to antibiotics. They represent one of the biggest threats to patients in hospital settings.

The teams research, which appears in the Proceedings of the National Academy of Sciences, creates a promising avenue for the development of innovative strategies to treat a wide variety of diseases and hospital-acquired infections like pneumonia, as well as bloodstream and urinary tract infection.

Biofilm-associated infections are responsible for thousands of deaths across North America every year. They are hard to eradicate because they secrete a matrix made of sugar molecules which form a kind of armor that acts as a physical and chemical barrier, preventing antibiotics from reaching their target sites within microbes.

We were able to use the microbes own tools against them to attack and destroy the sugar molecules that hold the biofilm together, says the studys co-principal investigator, Don Sheppard, director of the Division of Infectious Diseases at the McGill University Health Center and scientist from the Infectious Diseases and Immunity in Global Health Program.

Rather than trying to develop new individual bullets that target single microbes we are attacking the biofilm that protects those microbes by literally tearing down the walls to expose the microbes living behind them. Its a completely new and novel strategy to tackle this issue, Sheppard says.

This work is the result of a four-year successful collaboration between Sheppards team and scientists in the laboratory of P. Lynne Howell, senior scientist in the Molecular Medicine program at the Hospital for Sick Children (SickKids). They have been working to combat biofilms for several years, focusing on two of the most common organisms responsible for lung infections: a bacterium called Pseudomonas aeruginosa and a fungus called Aspergillus fumigatus.

Infections with these organisms in patients with chronic lung diseases like cystic fibrosis represent an enormous challenge in medical therapy.

While studying machinery that these organisms use to make their biofilms, the scientists discovered enzymes that cut up the sugar molecules, which glue biofilms together.

Microbes use these enzymes to move sugar molecules around and cut them into pieces in order to build and remodel the biofilm matrix, says Sheppard, who is also a professor in the medicine, microbiology, and immunology departments at the university. The researchers found a way to use these enzymes to degrade the sugar armor, exposing the microbe to antibiotics and host defenses.

We made these enzymes into a biofilm destroying machine that we can use outside the microbe where the sugar molecules are found, explains co-first study author Brendan Snarr, a doctoral student in Sheppards laboratory. These enzymes chew away all of the sugar molecules in their path and dont stop until the matrix is destroyed.

Previous attempts to deal with biofilms have had only limited success, mostly in preventing biofilm formation. These enzymes are the first strategy that has ever been effective in eradicating mature biofilms, and that work in mouse models of infection, adds Sheppard.

When we took the enzymes from bacteria and applied them to the fungi, we found that they worked in the same way on the fungi biofilm; which was surprising, says Howell, the studys co-principal investigator, who is also a professor in the biochemistry department at the University of Toronto.

Whats key is that this approach could be a universal way of being able to leverage the microbes own systems for degrading biofilms. This has bigger implications across many microbes, diseases, and infections.

Over 70 percent of hospital-acquired infections are actually associated with biofilms and we simply lack tools to treat them! says Sheppard. According to both lead scientists, the potential of this therapy is enormous and they hope to commercialize it in the coming years.

The Canadian Institutes of Health Research (CIHR); Cystic Fibrosis Canada; the Natural Sciences and Engineering Research Council of Canada (NSERC); Canada Research Chairs Program; the Fonds de recherche Quebec sant (FRQS); SickKids Foundation; and the Canadian Glycomics Network (GlycoNet), part of the Networks of Centres of Excellence of Canada funded the study.

Source: McGill University

See the original post here:

Use biofilm's own enzymes to defeat its 'armor' - Futurity: Research News

Exosomes Offer Enormous Potential as a Basis for Detecting and Treating Disease – AZoNano

Written by AZoNanoJun 23 2017

A new review highlights that tiny nanoparticles provide major potential in detecting and treating disease.

Exosomes can be produced by cells (left), altered before production or after purification (middle), and made in the laboratory (right) depending on their final use. CREDIT: Dr Marta I. Oliveira, INL, Portugal

Exosomes are tiny biological nanoparticles capable of transferring information between cells. These nanoparticles provide noteworthy potential in detecting and treating disease. This is considered to be the most comprehensive overview that has been concluded in this field of research.

According to Dr Steven Conlan from Swansea University, Dr Mauro Ferrari of Houston Methodist Research Institute in Texas, and Dr Ins Mendes Pinto from the International Iberian Nanotechnology Laboratory in Portugal, Regenerative Medicine and Cancer Treatment are the areas that could obtain benefits. Their commissioned paper, which is titled Exosomes as Reconfigurable Therapeutic Systems, was published on June 22nd, 2017, by Cell Press in Trends in Molecular Medicine.

Exosomes are particles developed by all cells present in the body and range from 30-130 nm in size - a nanometer refers to one-billionth of a meter. Exosomes behave as biological signaling systems, carrying proteins, lipids, RNA and DNA and communicating between cells. They are capable of driving biological processes, from transmitting information through breast milk to modulating gene expression.

The complete potential of exosomes is just slowly being revealed even though they were discovered in 1983. The Researchers demonstrate that the possible medical benefits of the nanoparticles fall into three broad categories:

Exosomes have a number of useful properties and one such property refers to their ability to cross barriers such as the plasma membrane of cells, or the brain/blood barrier. This allows them to be ideal for delivering therapeutic molecules in an extremely targeted manner.

The promising benefits of exosomes are discussed in a number of research projects - cited in the paper - under way or already completed, in the following areas:

The team points out that there is more to be done before research into exosomes translates into new treatments and techniques. It is essential to consider the side effects, and a standardized approach ideal for isolating, characterizing and then storing exosomes will have to be developed.

Researchers will also have to make sure that the properties of exosomes do not cause any harm, for example, it is possible for them to transfer drug resistance and also pacify the immune system.

However, the potential indeed is extremely clear, with the Researchers describing exosomes as "increasingly promising".

Professor Steve Conlan of Swansea University Medical School, one of the authors of the paper, said,

"Our survey of research into exosomes shows clearly that they offer enormous potential as a basis for detecting and treating disease.

Further studies are necessary to turn this research into clinical outcomes, but researchers and funders should be very encouraged by our findings. Our own research in Swansea is investigating the use of exosomes and exosome-like synthetic nanoparticles in combatting ovarian and endometrial cancer.

Progress in this field depends on partnership. As the authorship of our own paper illustrates, researchers in different countries are increasingly working together in nanohealth. Swansea University has wider links with Houston and Portuguese based researchers in the field.

It's also important to build partnerships outside academia, in particular with government and companies in this fast-growing sector."

See the original post here:

Exosomes Offer Enormous Potential as a Basis for Detecting and Treating Disease - AZoNano

Combined molecular biology test is the first to distinguish benign pancreatic lesions – Medical Xpress

June 23, 2017

When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely benign. The lesions almost never progress to cancer, so patients may be spared unnecessary pancreatic cancer screenings or operations. The two-test combination is the only one to date that can accurately and specifically identify these benign pancreatic lesions. Its utility was described in one of the largest studies of patients with this form of pancreatic lesion by researchers from Indiana University, Indianapolis. The results of the study now appear in an "article in press" on the Journal of the American College of Surgeons website in advance of print publication.

Between 2 to 3 percent of all patients have some type of pancreatic lesions or cysts revealed on routine abdominal diagnostic radiology scans.1 Nearly all of these patients will later develop pancreatic cancer. The most common and deadliest form of pancreatic cancerpancreatic adenocarcinomahas a five-year survival rate of 12 to 14 percent for early-stage disease and 1 to 3 percent for advanced disease, according to the American Cancer Society.2

A small percentage of patients have serous cystic neoplasms (SCN) that do not harbor malignant potential or progress to cancer. Nevertheless, these patients undergo imaging or other surveillance every six months to spot changes indicative of cancer, or they undergo an operation to remove part of the gland as a precaution because SCN are difficult to find using standard diagnostic methods. More than 60 percent of SCN are not predicted preoperatively3 and 50 to 70 percent are missed or incorrectly diagnosed on radiology scans. 4

However, the researchers determined that two proteins can play a significant role in ruling out precancer and cancer. Vascular endothelial growth factor A (VEGF-A) is a protein associated with promotion of new blood vessel formation. VEGF-A is upregulated in many tumors, and its expression can be correlated with a tumor's stage. Its utility in the diagnosis of pancreatic cysts was discovered by researchers at Indiana University. Carcinoembryonic antigen (CEA) is a protein associated with cell adhesion. It is present in low levels in healthy individuals, but it is increased with certain types of cancers.

Tests for each of these proteins in pancreatic cyst fluid have accurately distinguished SCN from other types of pancreatic lesions. In the present study, VEGF-A, alone, singled out SCN with a sensitivity of 100 percent and specificity of 83.7 percent, and CEA had a 95.5 percent sensitivity and 81.5 percent specificity.

Together, however, the tests approached the gold standard of pathologic testing: The combination had a sensitivity of 95.5 percent and specificity of 100 percent for SCN. Authors of the study concluded that results of the VEGF-A/CEA test could have prevented 26 patients from having unnecessary surgery.

"Every day, surgeons follow patients who have pancreatic cysts that have no risk of cancer but are still worrisome. They perform surgery or conduct diagnostic tests just to make sure they're not wrong. With VEGF-A and CEA, we believe we may have invented a test that can help that group of patients who don't have a risk of cancer get off the testing cycle and avoid surgery which, in and of itself, has a risk of mortality or complications," said C. Max Schmidt, MD, PhD, FACS, study author and professor of surgery and biochemical/molecular biology, Indiana University School of Medicine.

The study included 149 patients who underwent an operation to remove a pancreatic cystic lesion. Twenty-six of these patients had SCN. The diagnosis of each surgical specimen was confirmed by pathologic examination, and samples of pancreatic fluid from all patients were tested for VEGF-A and CEA according to testing protocols for enzyme-linked biochemical analysis of fluids.

The accuracy of the VEGF-A/CEA test needs to be confirmed in large prospective studies. The test itself needs to be performed under quality control conditions. Until a central laboratory is created to meet standards for cystic fluid analysis, Dr. Schmidt recommends that pancreatic surgical programs send specimens to the Indiana University Health Pancreatic Cyst and Cancer Early Detection Center in Indianapolis.

"Many investigators are looking for biological markers to help them understand which pancreatic cysts go on to form cancers. Our laboratory is doing that, but it's also looking for markers to help determine which ones never have the chance of becoming cancers in the first place. These are benign, and they're fooling us into thinking they could become cancers. If we can do that with confidence, we'll find patients who can avoid potentially morbid surgery on the pancreas to remove something that never needed to be removed," Dr. Schmidt said.

In addition to Dr. Schmidt, Rosalie A. Carr, MD; Michele T. Yip-Schneider, PhD; Scott Dolejs, MD; Bradley A. Hancock, BS; Huangbing Wu, BS; and Milan Radovich, PhD, participated in the study.

"FACS" designates that a surgeon is a Fellow of the American College of Surgeons.

Prior to publication, study results were initially reported at the Western Surgical Association 124th Scientific Session in November 2016. This study was supported by the Indiana Clinical and Translational Sciences Institute funded, in part by Grant Number UL1TR001108 from the National Institutes of Health, National Center for Advancing Translational Sciences, Clinical and Translational Sciences Award, and by a grant from the Lustgarten Foundation and the Indiana Genomics Initiative of Indiana University, supported in part by Lilly Endowment Inc.

Explore further: Game changer: Biomarker identified for noncancerous pancreatic cysts

More information: et al, Pancreatic Cyst Fluid Vascular Endothelial Growth Factor A and Carcinoembryonic Antigen: A Highly Accurate Test for the Diagnosis of Serous Cystic Neoplasm, Journal of the American College of Surgeons (2017). DOI: 10.1016/j.jamcollsurg.2017.05.003

1 Laffan TA et al. Prevalence of unsuspected pancreatic cysts on MDCT. AJR 2008; 191:802-7.

2 American Cancer Society. Pancreatic Survival Rates by Stage: https://www.cancer.org/cancer/pancreatic-cancer/detection-diagnosis-staging/survival-rates.html. Accessed June 21, 2017.

3 Kimura W et al. Multicenter study of serous cystic neoplasm of the Japan pancreas society. Pancreas 2012;41:380-7.

4 Bassi C, et al. Management of 100 consecutive cases of pancreatic serous cystadenoma: wait for symptoms and see at imaging or vice versa? World Journal of Surgery 2003;27:319-23.

Researchers at the Indiana University School of Medicine have discovered a highly accurate, noninvasive test to identify benign pancreatic cysts, which could spare patients years of nerve-racking trips to the doctor or potentially ...

A look back at more than half a million patient records has established that patients with pancreatic cysts have a significantly higher overall risk of pancreatic cancer compared to those without such cysts, according to ...

Scientists say they've developed a new blood test for identifying pancreatic cancera step that might eventually allow earlier diagnosis.

Pancreatic cancer has the lowest survival rate among all major cancers, largely because physicians lack diagnostic tools to detect the disease in its early, treatable stages. Now, a team of investigators led by Lev T. Perelman, ...

In a "look-back" analysis of data stored on 130 patients with pancreatic cysts, scientists at Johns Hopkins have used gene-based tests and a fixed set of clinical criteria to more accurately distinguish precancerous cysts ...

Pancreatic ductal adenocarcinoma is one of the most aggressive and deadliest forms of cancer. Treatment options are limited because symptoms typically do not appear until the disease is advanced and complete surgical resection ...

Imagine plopping six cups of coffee grounds on the heads of patients just before they are wheeled into the operating room to have nose or throat surgery?

The first ever randomised trial to investigate why some patients develop infections after their hip or knee replacement surgery, and which type of surgical revision treatment is best is being run by the University of Bristol ...

A new surgical technique devised by MIT researchers could allow prosthetic limbs to feel much more like natural limbs. Through coordination of the patient's prosthetic limb, existing nerves, and muscle grafts, amputees would ...

Ketamine was first introduced into clinical practice by investigators at the University of Michigan in the mid-1960s as a general anesthetic that could offer advantages, such a preserving breathing, not afforded by other ...

Every year, nearly 200,000 Americans turn to surgeons for help with their obesity, seeking bariatric surgery to lose weight and prevent life-threatening health problems.

A three-year study by QUT biomedical researchers in the Paediatric Spine Research Group (PSRG) aims to deepen our understanding of the concepts of comfort by using new techniques to look at how the spine reacts in different ...

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

See the original post here:

Combined molecular biology test is the first to distinguish benign pancreatic lesions - Medical Xpress

What Is Ghost Mode? How To Turn Off Snap Map So You Can Live In Peace – Elite Daily

It's no secret that I'm a fan of the many wonderful and teen ways you can fully utilize Snapchat.From snap sexting, to the ugly AF selfies I send my bestie on my morning commute, it's my sincere belief that Insta stories will never fully kill Snapchat.

Besides, who in their right mind would upload a nude to Instagram? Not me, because I have some tact, obviously.

Snapchat has this new featurecalled Snap Map, where you can literally see where all of your friends are and what they're doing. And when I say you can see where they are, I'm talking yes, exact location cross streets and all. In true snap ghost fashion, if you want to hide from people knowing your whereabouts, you can select ghost mode to opt out of the location tagging.

For reference, here's a screenshot of fellow Elite Daily editor Katie Corvino and I hanging out on the same street. She's the lively and beautiful cupcake Bitmoji, and I'm the dark and grim blue shadow (it's comforting).

If you click on the illuminated colors around the map, you can actually click into people's stories as they'redoing cool things around you.

Immediately, I can think of about 17,346,346 reasons why this is probably a bad idea. But the dark side of me also realizes how much I wish I had this when I was dating someone who lived outside of the city. Like, I could have done some serious stalking and ended up in a snap story sinkhole of watching his friends' stories that probably would have ended up in me being mad at him.

Teens these days really do have it all.

But also, like, what about the times when I tell all my friends I'm definitely not going out and they stalk me on Snap Map only to realize that I'm actually out with another group of friends I didn't want to tell them about?

Also! What about Kylie Jenner?! She already worries about stalkers enough as it is, and I'm sure she's too busyto realize she needs to turn the map feature off in good ol' Calabasas.

OK, so now that I've psyched myself out enough that I'm definitely never using Snap Map, how the f*ck do I turn it off?

Well, my friends, let me introduce you to a little thing known as ghost mode.

Once you're in camera mode in Snapchat, use two fingers to squeeze the camera screen toward the center. Here is where your Snap Map is located.

There's me again: ghostly blue figure with three vibrant gal pals surrounding me.

If you look at the top right corner of the map, you'll see the settings button. Click that to reveal your settings options.

As you can see, I have my settings checked so that all of my friends can see my location. Selecting ghost mode ensures that no one not even your friends will be able to keep tabs on your whereabouts or be able to see what you're up to.

The only Snapchats they will be able to view are the ones you post publicly to your story.

Make sure ghost mode is illuminated in green, and you're good to go!

Whew. Now you can breathe a breath of relief because you are now free to live your life totally and completely the way nature intended: in solitary, probably with AC blasting, watching an entire season ofOrange Is The New Black in one sitting.

Definitely make sure you go invisible if you don't want friends checking up on you. But maybe limit the amount of people you tell about this, since, well, you still obviously want to keep tabs on them.

Subscribe to Elite Daily's official newsletter, The Edge, for more stories you don't want to miss.

Brittany is a San Antonio, Texas native, and holds a degree in magazine journalism and English from Syracuse University. She has been published in Time Out New York in addition to Elite Daily, where she currently works as a senior editor.

Go here to read the rest:

What Is Ghost Mode? How To Turn Off Snap Map So You Can Live In Peace - Elite Daily

iCloud Photo Library’s sync need fixing – Macworld

By Kirk McElhearn, Senior Contributor, Macworld | Jun 23, 2017 4:00 AM PT

It's the little bugs that bug the most.

I love iCloud Photo Library. Its brain-dead simple to use (unlike iCloud Music Library), and it ensures that all my photos are in sync on all my devices. Lately, having bought a new camera, Ive been taking a lot of pictures, and Ive been wanting to view them and edit them on my iPad, with Enlight or Affinity Photo, a powerful photo editing app that was highlighted in Apples recent WWDC keynote. But syncing from my iMac, where I import photos, to my other devices can take a long time.

There are a few reasons for this. One is that my upload speed is slow. Since I shoot both RAW and JPEG, Photos has both files in its library for each picture, and together they take up about 25MB. So if I import a bunch of photos, theres a lot of data to upload.

And Photos doesnt let you control its upload, at least not easily. Even after I import photos and delete the ones I dont want to keep, Photos wants to upload them, because theyre in the Recently Deleted album. This album is a good thing, because it means that if you delete a photo, then later decide that you really did want to keep it, you have a month to change your mind. But if I import, say, 100 photos, and keep a half dozen, Photos still wants to upload all these pictures to the cloud, then down to each of my devices. Id rather that Photos not upload the Recently Deleted photos, at least not right away, perhaps deferring them until some time when Im not doing anything on my Mac. Unfortunately, when I import photos from a memory card, Photos immediately starts uploading them, whether I keep or delete them.

Ive found a workaround, but one thats clunky. In Photos preferences, on the iCloud tab, you can pause or resume photo upload. This is especially useful when you first turn on iCloud Photo Library, since there can be a lot of data to upload.

You can pause or resume photo uploads from the preferences.

To keep my bandwidth free, and to not waste time uploading lots of photos I wont keep, I go to the preferences and pause the upload. But if I do it after Ive imported the photos, then delete some or most of the photos, Photos still tries to upload all the pictures, because theyre in the Recently Deleted album.

The only way I can get photos to upload smoothly is to pause the upload in the preferences first, import the photos, delete the ones I dont want, empty the Recently Deleted album, and then turn uploading back on.

Even when Ive done that, its a crap-shoot as to how long it will take for the photos to show up on my other devices. Sometimes its fairly quickly, sometimes it can take more than an hour after Photos on my iMac has finished uploading. And this is just syncing thumbnails; I still need to download files if I want to do anything more than view them in the Photos app.

Now if I really want to work on a photo, there are other options. I can use AirDrop, for example, to send it from my iMac to my iPad. But then Ill have a duplicate. I may have, say, cropped a photo on my iMac, or started tweaking the RAW file in Photos, and if I export it to the Finder, Ill have the original, unmodified file, not one with my changes.

While features like Handoff and Continuity work more or less reliably these days, its a lot harder to have that continuity with Photos. Its not just my limited upstream bandwidth that slows things down, its whatever happens in iCloud that makes syncing lag.

With photos being such an important feature for iOS and Mac users, it would be helpful if this photo syncing was a bit faster. I can sync files to my Dropbox folder and see them immediately on other devices. Why cant Apple do the same?

Read more here:

iCloud Photo Library's sync need fixing - Macworld

Overwatch patch 1.13 brings Loot Box tweaks and highlight video uploading to the PTR – PCGamesN

Subscribe to PCGamesN on YouTube

Weve only just had one patch go live, but Blizzard have released a brand new one into the PTR. This one doesnt have any big character changes, though - its just a couple of rather big quality of life improvements.

Our list of the best multiplayer games is the article for you.

I dont know about you, but I quite fancy having fewer duplicates in my Loot Boxes. I also dont mind the idea of being able to save and easily share my highlight videos on social media. In 4K too!

Heres whats on offer in patch 1.13.

Loot Boxes will now give out drastically fewer duplicates, so you should be able to unlock stuff for your favourite characters more easily. If youre worried about taking a hit in Credits, Blizzard are also upping the Credits earned from Loot Boxes, so you should earn around the same, if not more, under the new system. Of course, the PTR exists to tweak how it works.

With that in mind, all players who log in to the PTR this patch cycle will receive five PTR Loot Boxes. These are standard loot boxes that will only be available on the PTR. Any items earned from Loot Boxes or unlocked via Credits on the PTR will not transfer over to your live account.

The highlights system has received several major updates:

Follow this link:

Overwatch patch 1.13 brings Loot Box tweaks and highlight video uploading to the PTR - PCGamesN

Pokmon Sun and Moon – Festival Plaza, how to trade, use GTS, and battle online explained – Eurogamer.net

The awkward online and multiplayer functions of the Festival Plaza explained.

By Chris Tapsell Published 23/06/2017

The Festival Plaza in Pokmon Sun and Moon can, at times, seem like a bit of an impenetrable mess, particularly when it comes to the relatively simple features of trading and battling online.

Things are made a little more complicated than they need be at times, and so with that in mind we've put together this quick and dirty guide for getting you up and running with the Festival Plaza's online and communications features as easily as possible. Expect simple walkthroughs here for Link Trading online with friends, trading using the GTS, Wonder Trade, plus tips for setting up Link Battles and visiting the Battle Spot.

There are three ways to trade in Pokmon Sun and Moon: Link Trades, the GTS, and Wonder Trade. All three are accessed through the bottom screen after entering the Festival Plaza. Here's the difference between each:

With those explained, let's go through step-by-step how to take part in a trade online.

How to Link Trade:

How to Trade on the GTS:

How to Wonder Trade:

Need more tips? Use our Pokmon Sun and Moon Walkthrough and guide for the main story, our competitive training guide for info on IVs, EV training, Hyper Training and bottle cap farming, and breeding explained, our choice of the best Pokmon Sun and Moon starter from Rowlet, Litten and Popplio, as well as an in-progress list of where to find Zygarde Cells and Cores and our guide to the Battle Tree and both Battling and Trading in the Festival Plaza. We also have a list of QR codes list, Z Crystal locations, Mega Stone locations, Eevium Z Eevee User locations for Extreme Evoboost, evolutions for Alolan Forms and other new Sun and Moon Pokmon and fast way to increase a Pokmon's Happiness, plus how to transfer across Ash-Greninja from the Sun and Moon Demo, where to catch the Tapu Guardians, how to catch the Ultra Beasts, and how to download the Munchlax Mystery Gift.

Both the Link Battles and Battle Spot work in a largely similar way to the trades above. You'll need to connect to the internet, select Battle from the bottom screen, and then choose the type of battle you'd like to hold, with Link Battles the go-to option for battling a specific person on your Friends, VIP, or Guest Lists.

That's it for our quick rundown of the Festival Plaza's online communication features, but be sure to check out our detailed guide to the Battle Tree, plus Mega Stone locations, and where to find all of the Z Crystals for further competitive, postgame content - plus, if you're still working your way through the main story, our main Pokmon Sun and Moon Walkthrough and Guide has absolutley everything you need to know.

See the original post:

Pokmon Sun and Moon - Festival Plaza, how to trade, use GTS, and battle online explained - Eurogamer.net

Trinity Right To Denounce Deplorable Posts – Hartford Courant

College professors have every right to be provocative, even outrageous, in their efforts to challenge established biases and inspire creative thought. But to incite rage with cruelty, to the point where safety is compromised that's different.

Faced with a situation that went beyond the boundaries of merely provocative, Trinity College President Joanne Berger-Sweeney responded with aplomb this week, decrying the irresponsible use of academic license and calling for a review of the incident to determine if college policies were violated.

The issue arose when Trinity Associate Professor Johnny Eric Williams posted on Facebook a link to an essay that many found objectionable at best.

Titled "Let Them [Expletive] Die," the essay encouraged people to "do nothing" if they saw "the bigots" in life-threatening situations and ended with the exhortation to "Let. Them. [Expletive]. Die. And smile a bit when you do."

Mr. Williams repeated the essay's title in subsequent Facebook posts, including one calling for an "end to the vectors of their destructive mythology of whiteness and their white supremacy system."

Many saw it as an endorsement of the thinking behind the essay, a stance Mr. Williams denied.

"This was an admittedly provocative move to get readers to pay attention to my reasoned, reasonable, and yes angry argument," he wrote, meant "to draw the attention of the readers to the current dire state of white supremacy in the nation."

If he meant to be provocative, he succeeded. But he also created an unsafe atmosphere at the college, which was shut down for a day in response to threats. Free speech has consequences. Mr. Williams is a member of a broader community at Trinity and should have kept that in mind.

Trinity College / HANDOUT

Johnny Eric Williams, associate professor of sociology at Trinity College. (Trinity College) User Upload Caption: Johnny Eric Williams, associate professor of sociology at Trinity College. (Trinity College) hc

Johnny Eric Williams, associate professor of sociology at Trinity College. (Trinity College) User Upload Caption: Johnny Eric Williams, associate professor of sociology at Trinity College. (Trinity College) hc (Trinity College / HANDOUT)

Ms. Berger-Sweeney told Mr. Williams that "his use of the [title of the essay] was reprehensible," she wrote to the Trinity community. "No matter its intent, it goes against our fundamental values as an institution, and I believe its effect is to close minds rather than open them."

That's the right approach. The title was uncivil, even heartless. It provokes anger and was not worthy of a teacher of young minds.

Mr. Williams' tacit endorsement of a mindset so abhorrent was remarkably poor judgment. Ms. Berger-Sweeney is right to denounce it, yet she should ensure that the college's response doesn't squelch vigorous, even uncomfortable, debate.

Here is the original post:

Trinity Right To Denounce Deplorable Posts - Hartford Courant

Shawnee County Safe Kids recommendations on kid medicine safety – KSNT News

TOPEKA, Kan. (KSNT) Promoting curiosity in our kids is a good thing! But experts stress doing it in a safe way. Curiosity for medications, is a serious problem today.

According to the Safe Kids Shawnee County coordinator, Teresa Taylor it is absolutely a problem.

It is a very common thing for children to get into medications that arent intended for them or take too many of something that was intended for them.

A major problem is that many medicines look like candy.

You can see here how so many different medications and they look just like candy and its even hard for adults to tell what is what on those. Its really important that we never refer to medication as candy. Sometimes well say things to get kids to go ahead and take their medicines. Its often sweetened so that they will take it and its a little more palpable for them. But we should never refer to it as candy because we dont want to encourage getting into it later, said Teresa.

Its very important to store medicine in a safe location, where your kids wont find them.

Teresa said some of the common culprits that you wont typically think of are night stands.

When medications are kept in or on a night stand. Children can commonly get into them. Also purses and bags.

Medication safety is not just for younger children. Safe Kids Shawnee County says adults should model good behavior for older kids to follow.

We model good behavior. So kids will naturally do what we do, rather than what we tell them to do. If we read the medication label every time, and follow the labels when we take medicine, theyll be more likely to do that. As they get even older, review that medication labels with them, and teach them about the different components on (the bottle) and how to take medicine safely. They need to take them exactly as prescribed. Taking more doesnt mean it will work better or faster, said Teresa.

To avoid any accidental overdoses, make sure you closely follow dosage recommendations and relay any medication instructions to temporary caregivers.

Vitamins, eye drops, and diaper remedies are also common items for kids to get into. Safe Kids Shawnee County recommends having the Poison Control phone number on hand at all time 1-800-222-1222. You can also text POISON to 48484.

Like Loading...

Read the rest here:

Shawnee County Safe Kids recommendations on kid medicine safety - KSNT News

Supporting medicine and its finest practitioners – Washington Times

ANALYSIS/OPINION:

Treating emergencies isnt your insurance talking. Its doctoring. Its nursing. Its medical technology. Its your stone-filled gallbladder obstructing and a top surgeon operating on it without delay. You cant prove that a junior attending surgeon wouldnt do just as well, but you can feel it when the wound is healing so well two days later where the angry raw organ was scope-sucked successfully from your body.

The best of emergency health care is what we saw represented on the television screen last week, as top doctors came forward to describe their craft, a reminder that the health insurance future weve all been debating lacks real flesh on its bones. An insurance company cant manufacture or guarantee the dedication or skill of a Dr. Jack Sava, head of trauma at Medstar Washington Hospital Center, who directed the lifesaving interventions for House Majority Whip Steven Scalise.

Damaged blood vessels and pelvic organs torn asunder by the wide tracking fragments of a speeding bullet were meticulously repaired. The miracle medical crew managed to pour blood in faster than it was pouring out while managing to preserve essential blood flow to the brain. There will be a long rehab process ahead with pain management and infection control and more surgical repair. Top doctors and nurses will be needed throughout the healing process.

No one-size-fits-all health insurance can guarantee that the best surgical and rehab teams will always be available in lower-profile cases at less prominent trauma centers.

Also appearing at a televised press conference last week was the top team of doctors at the University of Cincinnati Medical Center who received patient and victim Otto Warmbier from North Korea. Dr. Daniel Kanter, medical director of the neuroscience intensive care unit revealed that poor Otto had suffered severe brain damage and was rendered unresponsive from apparent stoppage of breathing and cardiac arrest likely from a pill or poison hed been given and according to neurological testing not from botulism as the North Koreans had claimed. Warmbier sadly died a few days later.

Dr. Kanter and his group also might have made a difference if they werent tragically reduced to an after-the-fact Sherlock Holmesian analysis.

Viewers could look to the screen and wonder would I receive such top-flight treatment if it were me?

The answer for the time being, more often than not, is still yes. But will doctors of this quality continue to survive amid the constrictions of a government/insurance bureaucracy?

Many years ago I was travelling through Europe and met a middle-aged bearded man driving an old VW minivan. He told me that he was a well-known oncologist who was paid the equivalent of $60,000 a year (in the 1980s) to care for very sick patients. He openly admitted that the best thing about his job was the time off it afforded him to travel.

We dont need that sober reality here. Unfortunately, both the Affordable Care Act and the replacement American Health Care Act (being debated in the Senate) rely on an expanded insurance model that limit the role of doctors. We are already struggling with a growing shortage, excess computer documentation and a rising fear of malpractice as we work to master the latest technology. At least the new bill removes the mandate to buy a product that doesnt guarantee you access to our actual care. Thats the right place to start, but it isnt the whole answer.

There needs to be a new focus on rewarding doctors for the work we do and allowing us more freedom to do it. We need less so-called comprehensive insurance and more available and affordable health care tools to choose from.

Marc Siegel, a physician, is a clinical professor of medicine and medical director of Doctor Radio at NYU Langone Medical Center. He is a Fox News medical correspondent.

Read more:

Supporting medicine and its finest practitioners - Washington Times

Is Modern Medicine a Luxury? – HuffPost

Welp, here it goes. I cant be silent. I reviewed the Senate Healthcare Bill, and it affects my son. I dont know if my blogging does a darn thing, but I believe Im obligated to advocate for my child. As such, doing what I can to ensure that people are aware of the ramifications of this bill and asking those who care to make their voices heard, is the least I can do.

For the sake of brevity, I will keep this to the two factors which have the greatest impact on my child. The photos below were taken from an NPR summary of the bill.

Image Courtesy of NPR

Many people think that Medicaid is a hand out to able bodied people who choose not to work. However, around 90% of Medicaid dollars go to the elderly, disabled or working people whose income falls below the threshold in their state. Therefore, reduced funding to the program hits heaviest on the most vulnerable populations. As adults, both of my sons will rely on Medicaid for their medical coverage. Its not exactly clear what these cuts will mean to them, and perhaps thats the most worrisome part of this. Alex might be just fine if he stays healthy, but Benjamins health needs are lifelong. If he cannot stay on our healthcare plan, and Medicaid is cut, what would the options be? Nothing here is clear, and for families like ours its terrifying.

Image Courtesy of NPR

This part is even more harrowing. In addition to his developmental and medical needs, Ben has serious mental health needs. He sees a psychiatrist, uses psychiatric medicine, and needs autism therapy, which is a mental health benefit. Without these in place, his wellbeing is in jeopardy. I cannot overstate the seriousness of this situation. As it is, resources for people with developmental, medical and psychiatric needs are sparse, if funding is cut, it would be nothing short of devastating for Ben and our family.

But we arent the only ones. In fact, were pretty fortunate so far. My husband works for the state and has his choice of excellent healthcare plans, of which we have chosen the most thorough and economical coverage. Many are self employed without access to such benefits. For us, the cost of healthcare thus far has been a seriious strain, but one that we can manage. For many, its already past management and only set to get worse, highlighted in this Washington Post article.

Ive followed Parkers story for years now, and his family deserves better. Theyre working hard, being resourceful, and just want their son to live!

Heres the thing, we have spectacular medical science thats evolving and growing daily. We are able to save lives that just a few years or decades ago were hopeless. Its marvelous, simply marvelous. But its expensive, as would be expected, too expensive for any but the wealthiest citizens to afford. Do we reserve such marvels for those who can afford to buy it? Is modern medicine a luxury for the few? Is it a commodity available to only those who have the cash reserves to pay for it?

How do we decide who gets this care? Do we deny children whose parents dont have jobs with a hearty benefit package? Or do we put caps on it and say we can only spend so many dollars to save a persons life, and after that just shrug it off? Or do we leave people with mental illness without access to health insurance? This is dangerously close to eugenics. I shudder to think that denying Medicaid coverage for mental illness is a tidy way of saying society shouldnt be obligated to help them.

Finally, I want to point out that its the pro-life party that is endorsing all of this, and Im calling bullshit. There is nothing life affirming or life-protecting about any of this. This is prioritizing finances over people and its repugnant. If you suggest that charities or churches should fill in the gaps, please just get off that ridiculous notion. In eleven years of managing complex medical, developmental and psychiatric needs, we have tapped into private resources to a great extent, Im quite savvy at finding and accessing them, and we have had a church with a congregational care employee who identifies and designates church resources for families in crisis. Between the two, the help has been incredibly helpful for certain things, but only a drop in the bucket compared to the day to day impact of copays, deductibles, time and miles. Its simply not feasible for private organizations to offset such monumental costs.

So I ask you, do you really think its okay for people to suffer and die when medical care is available, but not affordable?

The Morning Email

Wake up to the day's most important news.

Go here to see the original:

Is Modern Medicine a Luxury? - HuffPost

Medical school professor studies chronic illness in people over 100 years old – GW Hatchet (subscription)

A medical school professor is researching the presence of chronic illness in patients age 100 and older.

Raya Kheirbek, an associate professor of medicine, said that this generation of centenarians, people in their 100s, are one of the fastest growing populations in the U.S., but they have not been adequately studied by medical researchers. Her research, which was released in April, was reviewed by the Journal of American Geriatrics last week.

I think its important that we look into a generation that no one looks into, she said. We dont really have enough evidence based in literature and most of those patients dont make it to the end of clinical trials.

Kheirbek said that her interest in the topic began when she treated a 108-year-old women who was part a case study prior to her current project. She said the patient was suffering from vascular disease, heart failure, hypertension and general frailty, but her mind was sound.

I said to myself, she is so resilient, and Id like to study the group to see what factors contribute to their well being, she said.

Kheirbek said that her past research focused on developing models to predict how long someone with a chronic illness has left to live. She said that this prediction method was often no better than making an educated guess because unmeasurable factors like psycho-social conditions play an important role in modeling someones life-expectancy.

Kheirbeks most recent research focused on patients in areas of Virginia utilizing medical records from 3,351 centenarians, she said. The study exaamined the patients lifespan and healthspan, the amount of time someone lives in good health.

This data was compared to records from 31,121 octogenarians, people age 80 and older, and 52,420 nonagenarians, those 90-years-old and above, according to the study.

Kheirbek said her study looked at veterans in the Virginia area in particular. She said she was interested in how this generation coped with the stress of events like World War II and the Great Depression.

The current generation age 100 and older often didnt smoke or consume alcohol, and obesity was nearly nonexistent, she said. Kheirbek added that those approaching 100 were less likely to have chronic illnesses than people from age 80 to 90.

These are people that survived the evils of poverty and the evils of war, and made it to that age, Kheirbek said. Its important for me now to dig deeper into that group and try to figure out if I can capture their resilience.

Kheirbek said that the next steps of the study will be to investigate methods of resilience training for younger generations as a way to help them cope with anxiety and depression.

Additionally, Kheirbek said she is looking at the presence of mental illness, the rate of dementia, and cardiovascular risks.

Continue reading here:

Medical school professor studies chronic illness in people over 100 years old - GW Hatchet (subscription)

Liberty Chamber of Commerce seeking vendors and parade participants for July 4 Celebration – Times Herald-Record

LIBERTY The Greater Liberty Chamber of Commerce, in cooperation with the Village and Town of Liberty, will be hosting its annual Fourth of July Celebration on July 4. A rain date is set for July 8.

The Chamber is inviting retail, food and craft vendors as well as community organizations to participate in the annual Street Fair and Parade. The street fair runs from 10:30 a.m.-4:30 p.m, with the parade kicking off at 12:05 p.m. across from the Elks Lodge on Oberferst Street. North Main Street will be closed to vehicle traffic to accommodate the festivities.

The day also includes: A Classic Car and Truck Show beginning at 10:30 a.m. (preview 9 a.m.) behind the Liberty Public Library; a special performance of the Star Spangled Banner at noon on the Main Street stage; a variety of food, craft and retail vendors; bouncy houses and kids activities by Party Master; and musical guest The Other Band on the Main Street stage starting at 12:30 p.m.

Vendor applications can be found at LibertyNYChamber.com. For more information about the Chamber, or to participate in the parade or volunteer on the day of the event, contact the Chamber at 292-9797 or email info@LibertyNYChamber.com. Information can also be found on the Greater Liberty Chamber of Commerce Facebook page.

All local service organizations, volunteer groups, businesses, classic car and tractor owners, etc. are encouraged and welcomed to show their pride and participate in this years parade. Lineup begins at 11 a.m. Parade kicks off at 12:05 p.m. sharp.

For more information or for other upcoming Liberty Chamber events, as well as to join, or to volunteer call 292-9797 or email info@LibertyNYChamber.com. Information can also be found on the Greater Liberty Chamber of Commerce Facebook page or go to LibertyNYChamber.com.

More:

Liberty Chamber of Commerce seeking vendors and parade participants for July 4 Celebration - Times Herald-Record

Bishops address religious liberty, health care, worship – St.Louis Review

Bishop Kevin C. Rhoades of Fort Wayne-South Bend, Ind., left, and Bishop Shelton J. Fabre of Houma-Thibodaux, La., prayed June 14 during the opening session of the U.S. Conference of Catholic Bishops annual spring assembly in Indianapolis.

Sean Gallagher | The Criterion

INDIANAPOLIS Reflecting their concern that religious liberty at home and abroad remains a top priority, the U.S. bishops during their spring general assembly in Indianapolis voted to make permanent their Ad Hoc Committee for Religious Liberty.

Voting 132-53 with five abstentions June 15, the second day of the assembly, the bishops' action came less than a week before the start of the U.S. Conference of Catholic Bishops' fifth annual Fortnight for Freedom June 21-July 4. The observance is a two-week period of prayer, advocacy and education on religious freedom.

The bishops also reiterated that their efforts are focused on "ensuring the fundamental right of medical care" for all people as the U.S. Senate worked in mid-June on a plan to repeal and replace the Affordable Care Act after the U.S. House of Representatives had passed its own measure, the American Health Care Act.

The chairman of the National Review Board, which works to respond to and prevent sexual abuse by clergy and other church personnel, updated the bishops June 14 on the board's work and presented key points of the recently issued 14th annual report on diocesan compliance with the U.S. Catholic Church's "Charter for the Protection of Children and Young People."

In a related event, the bishops celebrated a liturgy in response to a call from Pope Francis to episcopal conferences around the world to observe a "Day of Prayer and Penance" for survivors of sexual abuse within the Church.

The bishops also heard reports from the chairman of the Committee on International Justice and Peace about international persecution and human rights violations; final plans for the July 1-4 "Convocation of Catholic Leaders: The Joy of the Gospel in America" in Orlando, Florida; and the progress of a working group on migrants and refugees.

Before the vote on making the Committee on Religious Liberty permanent, Baltimore Archbishop William E. Lori, committee chairman, said the need for the body stretches beyond the specific legal and public policy issues challenging religious freedom that continue to emerge.

Archbishop Lori expressed hope that the committee's work would help "plant the seeds of a movement for religious freedom, which will take years of watering and weeding in order for it to grow, to grow strong and to bear fruit."

Worldwide, Bishop Oscar Cantu of Las Cruces, New Mexico, international policy committee chairman, said in a June 15 report that religious persecution "includes both social hostilities and government restrictions."

"It finds expression in physical assaults, arrests and detentions, desecration of holy sites, and in discrimination against religious groups in employment, education, housing, the selection of a marriage partner and whether you are considered a citizen."

He said the committee respects "the approaches adopted by the local Church. Like a physician, our first duty is to do no harm. We adopt strategies that complement the work of the local Church."

Health Care

The USCCB reinforced its stand that the American Health Care Act passed by the House of Representatives May 4 needs major reform to provide quality health care for the "voiceless," especially children, the elderly, the poor, immigrants and the seriously ill.

"We find ourselves in a time marked by a deep sense of urgency and gravity," said Bishop George L. Thomas of Helena, Montana, in remarks to the assembly. "Within two weeks, we may see a federal budgetary action with potentially catastrophic effects on the lives of our people, most especially children and the elderly, the seriously ill, the immigrant and our nation's working poor."

Referring to the House bill and its plan to "eliminate $880 billion from Medicaid over the next decade," Bishop Thomas said, "If left unchallenged or unmodified, this budget will destabilize our own Catholic health care apostolates, take food from the mouths of school-aged children and the homebound, and deny already scarce medical resources to the nation's neediest in every state across the land."

His comments followed a report on health care reform by Bishop Frank J. Dewane of Venice, Florida, chairman of the USCCB's Committee on Domestic Justice and Human Development.

Bishop Dewane focused on the Senate's work to repeal and replace the Affordable Care Act.

"The Catholic Church remains committed to ensuring the fundamental right to medical care, a right which is in keeping with the God-given dignity of every person," Bishop Dewane said. He told his fellow bishops that the USCCB has been in contact with members of Congress. Noting that the USCCB sent a letter to U.S. senators June 1, Bishop Dewane said, "It called on the Senate to strip away harmful promises of the AHCA or start anew with a better bill."

Migrants and refugees

Meanwhile, the bishops' working group on migrants and refugees was set to complete its work by the spring assembly, but Cardinal Daniel N. DiNardo of Galveston-Houston, USCCB president, announced June 15 he was extending the group "recognizing the continued urgency" so many migration and refugee issues present.

Archbishop Jose H. Gomez of Los Angeles, USCCB vice president and the group's chairman, and Bishop Joe S. Vasquez of Austin, Texas, chairman of the USCCB Committee on Migration, outlined the working group's origins, activities and next steps on issues.

Young people

The spiritual life of young people also was discussed during the opening day of the assembly.

Cardinal Joseph W. Tobin of Newark, New Jersey, and Archbishop Charles J. Chaput of Philadelphia opened the discussion with a presentation on the consultations and questions for the bishops to consider in preparing for the October 2018 Synod of Bishops on youth and vocations.

"The synod indeed comes at a critical time," Cardinal Tobin said. "We know that there are both challenges and opportunities here in the U.S. The increased amount of disconnected millennials is certainly a concern for us, as is the decline and the delay of marriage among young people. Still there are various positive signs to build upon."

Those signs, he said, include "the high interest among millennials during the liturgical seasons of Advent and Lent" and "the continued importance in our ministries and outreach to young people which have a positive effect on vocational discernment."

"The Church in the U.S. is poised to engage this conversation for and with young people," he added.

Sexual abuse

Francesco Cesareo, chairman of the National Review Board, urged the bishops June 14 to continue their commitment to stopping clergy sexual abuse and supporting victims of abuse "at the forefront" of their ministry.

He said sexual abuse of minors by clergy is "not a thing of past" and stressed the bishops have to always be vigilant and be sure to not "let complacency set in" in their efforts to stop it.

At a Mass as part of a "Day of Prayer and Penance" June 14 at Sts. Peter and Paul Cathedral some 200 bishops heard Atlanta Archbishop Wilton D. Gregory say in the homily that "we can never say that we are sorry enough for the share that we have had in this tragedy of broken fidelity and trust" in the clergy sexual abuse crisis in the Catholic Church.

Cardinal DiNardo, the principal celebrant, spoke about the pope's call at the liturgy's start.

"In solidarity with our brother bishops around the world, we acknowledge the sins that have occurred and ask forgiveness from and healing of those who have suffered abuse at the hands of those who should have been protecting and caring for them," he said.

At the end of the Mass, the bishops, in a sign of penance, knelt while praying a prayer of healing and forgiveness for the victims of sexual abuse in the church.

Missionary discipleship

The bishops were reminded June 15 that the historic Convocation of Catholic Leaders was nearing by Bishop Richard J. Malone of Buffalo, New York, chairman of the bishops' Committee on Laity, Marriage, Family Life and Youth. He noted that it will be the largest gathering sponsored by U.S. bishops and will be a time to show the unity of the Church.

The convocation, an invitation-only event, is meant to give the 3,000 participants expected to attend a better understanding of what it means to be missionary disciples in today's world through workshop presentations, keynote addresses and prayer.

In his address to the assembly Archbishop Christophe Pierre, apostolic nuncio to the U.S., called the bishops to be missionary disciples through listening and fostering solidarity and a culture of encounter. He encouraged the bishops to view current challenges as "a time of grace."

"Take courage," he said, when the "tasks of the new evangelization and of building a culture of encounter and solidarity seem daunting."

He reminded the bishops of Pope Francis' call to "go forth from our own comfort zone in order to reach all the peripheries in need of the light of the Gospel" and noted that many of them will be discussing this more at the convocation of Catholic leaders in Orlando, in July.

Worship and liturgy

The USCCB overwhelmingly approved revisions to the guidelines governing the celebration of sacraments for people with disabilities that take into account medical and technological developments. Passed 180-1 June 14, the revisions in the "Guidelines for the Celebration of Sacraments with Persons with Disabilities" updates a document that was adopted in 1995.

The guidelines were developed as a tool to improve access to the sacraments by persons with disabilities and reduce inconsistencies in pastoral practice.

In other votes, the bishops approved a new translation of the "Order of Blessing the Oil of Catechumens and of the Sick and of Consecrating the Chrism," 178-3. The ritual is used each year at diocesan chrism Masses. It will be sent to the Vatican's Congregation for Divine Worship and the Sacraments for its "recognitio," or final approval.

However, the bishops' approval of a collection of blessings in Spanish for use in the U.S. that complement English texts included in the "Book of Blessings" fell one vote short of reaching the threshold necessary to send it to the Vatican congregation for the recognitio.

The vote on the "Bendicional: Sexta Parte" (Part VI) was 171-2, with two abstentions. Voting will be completed by mail ballot with the Latin-rite bishops who did not attending the assembly.

Sean Gallagher, Natalie Hoefer and John Shaughnessy contributed to this story.

For more information about the Fortnight for Freedom, observed June 21-July 4, visit:

USCCB Resources:

http://www.stlouisreview.com/bJW

Archdiocese of St. Louis resources:

http://www.archstl.org/liberty

St. Louis Review stories:

http://www.stlouisreview.com/bJD

Bookmark/Search this post with

Read this article:

Bishops address religious liberty, health care, worship - St.Louis Review