Quantum Theory – Full Documentary HD

Check: https://youtu.be/Hs_chZSNL9IThe World of Quantum - Full Documentary HD http://www.advexon.com For more Scientific DOCUMENTARIES.Subscribe for more Videos...Quantum mechanics (QM -- also known as quantum physics, or quantum theory) is a branch of physics which deals with physical phenomena at nanoscopic scales where the action is on the order of the Planck constant. It departs from classical mechanics primarily at the quantum realm of atomic and subatomic length scales. Quantum mechanics provides a mathematical description of much of the dual particle-like and wave-like behavior and interactions of energy and matter. Quantum mechanics provides a substantially useful framework for many features of the modern periodic table of elements including the behavior of atoms during chemical bonding and has played a significant role in the development of many modern technologies.

In advanced topics of quantum mechanics, some of these behaviors are macroscopic (see macroscopic quantum phenomena) and emerge at only extreme (i.e., very low or very high) energies or temperatures (such as in the use of superconducting magnets). For example, the angular momentum of an electron bound to an atom or molecule is quantized. In contrast, the angular momentum of an unbound electron is not quantized. In the context of quantum mechanics, the wave--particle duality of energy and matter and the uncertainty principle provide a unified view of the behavior of photons, electrons, and other atomic-scale objects.

The mathematical formulations of quantum mechanics are abstract. A mathematical function, the wavefunction, provides information about the probability amplitude of position, momentum, and other physical properties of a particle. Mathematical manipulations of the wavefunction usually involve bra--ket notation which requires an understanding of complex numbers and linear functionals. The wavefunction formulation treats the particle as a quantum harmonic oscillator, and the mathematics is akin to that describing acoustic resonance. Many of the results of quantum mechanics are not easily visualized in terms of classical mechanics. For instance, in a quantum mechanical model the lowest energy state of a system, the ground state, is non-zero as opposed to a more "traditional" ground state with zero kinetic energy (all particles at rest). Instead of a traditional static, unchanging zero energy state, quantum mechanics allows for far more dynamic, chaotic possibilities, according to John Wheeler.

The earliest versions of quantum mechanics were formulated in the first decade of the 20th century. About this time, the atomic theory and the corpuscular theory of light (as updated by Einstein)[1] first came to be widely accepted as scientific fact; these latter theories can be viewed as quantum theories of matter and electromagnetic radiation, respectively. Early quantum theory was significantly reformulated in the mid-1920s by Werner Heisenberg, Max Born and Pascual Jordan, (matrix mechanics); Louis de Broglie and Erwin Schrdinger (wave mechanics); and Wolfgang Pauli and Satyendra Nath Bose (statistics of subatomic particles). Moreover, the Copenhagen interpretation of Niels Bohr became widely accepted. By 1930, quantum mechanics had been further unified and formalized by the work of David Hilbert, Paul Dirac and John von Neumann[2] with a greater emphasis placed on measurement in quantum mechanics, the statistical nature of our knowledge of reality, and philosophical speculation about the role of the observer. Quantum mechanics has since permeated throughout many aspects of 20th-century physics and other disciplines including quantum chemistry, quantum electronics, quantum optics, and quantum information science. Much 19th-century physics has been re-evaluated as the "classical limit" of quantum mechanics and its more advanced developments in terms of quantum field theory, string theory, and speculative quantum gravity theories. https://www.youtube.com/watch?v=ZsVGu...

quantum solace, quantum world, #quantum

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Quantum Theory - Full Documentary HD

Nano-Engineering | CBE – chemeng.ucla.edu

Professors Chang, Cohen, Christofides, Lu, Monbouquette, and Sautet

Research on surface chemistry and physics is the foundation for discovery of surface-engineered materials that have applications in the fields of separations, sensing, and semiconductors. Faculty in the Chemical & Biomolecular Engineering Department at UCLA work in the areas of macromolecular and nano-surface engineering to develop more efficient and selective membranes and sorption resins, design new molecular chemical sensors, synthesize biocompatible surfaces, and manipulate heterogeneous surface processes at the atomic scale.

Molecular modeling and experimental investigations are geared towards understanding the structure of silylated and graft-polymerized surfaces (e.g., topology, conformation and distribution) and devising physical and chemical methods (e.g., graft polymerization and self-assembly) to control surface properties. Recent major accomplishments in this area are patented ceramic-polymer composite membranes (Cohen Group). This membrane, with a nano-structured separation layer, has proven effective in protein ultrafiltration and pervaporation separation of organic-organic and organic-aqueous mixtures.

AFM Image of silicon wafer surface modified by graft polymerization of poly(vinyl acetate)

Molecular engineering of innovative, self-assembling systems that mimic biological systems is researched to solve technological problems. For example, an approach that magnetobacteria use has been harnessed to produce the magnetite particles needed for magnetotaxis in the synthesis of semiconductor nanoparticles (Monbouquette Group). Size monodisperse, 100-nm-diameter phospholipid vesicles serve as compartments for synthesis of <10-nm-diameter II-VI semiconductor nanocrystals of tightly controlled size and composition. Size and surface-engineered particles may find applications in lasers, flat-panel displays, and quantum computing.

Membrane Separation Technology

Professor Nobe also focuses on investigating physical properties of electrodeposited quantum dots, nanomagnets, nanowires (10 to 400 nm diam. with aspect ratios up to 18,000), nanostructured multilayers, and metal oxide and conducting polymer supercapacitors. The figure shows an example of an electrochemical nano system (ENS) where cobalt nanowires were electrodeposited from anodized alumina templates.

Electrodeposited cobalt nanowires (200 nm diam., 60 mm long) from anodized alumina.

Molecular engineering of innovative systems that mimic biological systems is researched to solve technological problems. Since the direct manipulation of individual molecules presents obvious technological difficulties, much of the research has focused on self-assembling systems. For example, Professor Monbouquettes group has borrowed an approach that magnetobacteria use to produce the magnetite particles needed for magnetotaxis in the synthesis of semiconductor nanoparticles. Size monodisperse, 100-nm-diameter phospholipid vesicles serve as compartments for synthesis of <10-nm-diameter II-VI semiconductor nanocrystals of tightly controlled size and composition. These nanoparticles exhibit size-dependent physical properties due to quantum confinement of electrons. Size and surface-engineered particles may find applications in lasers, flat-panel displays, and quantum computing. Monbouquettes group is also pursuing the use of quantum dots in creating surfaces with a feature size of 2-3 nm.

Electrophoretically mobile, photocatalytic CdS 2dots draw trails of reacted ligands on an atomically smooth substrate.

Atomic layer deposition (ALD) to engineer nanometer thin films and nanolaminates with atomic resolution and controllability is also being studied (Chang Group). Highly uniform, conformal, and stoichiometric films can be easily synthesized, for example, nanolaminates can be formed through the use of multiple chemical precursors in alternating reaction sequences. ALD has been used to deposit metals, metal oxides, metal nitrides, semiconductors, transparent conductive oxides, and ferroelectric materials, with potential applications in microelectronics, membrane, sensor, bioceramic, and catalysis.

ALD Graph thin films 5ALD Graph thin films 6ALD Graph thin films

Professor Hicks group has developed a method of simulating reactions on compound semiconductor surfaces using molecular cluster calculations with density functional theory. Using this method, a cluster model for a gallium arsenide surface has been developed, which identified all the reaction sites on the surface as being an arsenic dimer and two second-layer gallium atoms. Each arsenic dangling bond is filled with a pair of electrons, while each gallium dangling bond is empty, in excellent agreement with experimental observations. The most exciting result from this work is the prediction of the vibrational frequencies of the optimized clusters and their excellent comparison with infrared data. This unique capability allows a definitive assignment of the observed vibrational bands to specific adsorption sites. This method is currently being applied to the study of surface reaction mechanisms for organometallic precursors.

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Nano-Engineering | CBE - chemeng.ucla.edu

Satoshi Nakamoto Introduced Bitcoin 10 Years Ago …

Ten years ago today, someone using the name Satoshi Nakamoto sent an academic paper to a cryptography mailing list proposing a form of digital cash called "bitcoin." The pseudonymous Nakamoto, whose true identity remains unknown, described an idea for "mining" a limited amount of this virtual currency through a peer-to-peer scheme that wouldn't depend on a bank, government, or any other central authority. Once people started using bitcoin, it would be impossible for a government to pull the plug, as happened with previous attempts to create digital money, such as E-Gold.

Today Bitcoin is a global phenomenon. Individual bitcoins sell for thousands of dollars. The price has dropped steeply from its peak of nearly $20,000 in December 2017, but recall that, at the beginning of 2017, one bitcoin sold for less than $1,000. Meanwhile, hordes of other cryptocurrencies have launched, though none has attracted quite as much interest from users or investors as bitcoin, and venture capitalists pour millions into startups looking to capitalize on the underlying technology.

It all started with the white paper. When Nakamoto published the paper, many of the underlying concepts of Bitcoin already existed, including the idea of issuing digital money to people who devoted computing resources to a problem. But Emin Gn Sirer, a computer science professor at Cornell University, credits Nakamoto with a major breakthrough: a way to ensure that users trust one another, and the network, without relying on gatekeepers.

Bitcoin relies on a ledger called the blockchain. Every transaction is cryptographically signed and recorded in the blockchain, which is distributed to every participant in the Bitcoin network, preventing anyone from double-spending their coins.

Because its difficult, if not impossible, to tamper with the ledger, anyone can download the Bitcoin software and blockchain and participate in the network. There are no corporations that control entry into the network or government bureaucrats demanding that you file paperwork to participate. Building a currency system without the need for gatekeepers wasnt a problem many were focused on, but once it was solved it moved the idea of decentralized digital currency from the academic fringes to the nightly news.

"Proving that this was possible was a major contribution to computer science," Sirer says. "Satoshi opened the door to revamping the entire finance industry.

The rise of Bitcoin happened largely without Nakamoto, who disappeared from the internet in late 2010, leaving the Bitcoin software in the hands of some early collaborators. Attempts to track down Nakamoto have been at best inconclusive. They include a Newsweek cover story claiming that Nakamoto wasnt a pseudonym but the real name of a retired engineer living in Temple City, California, which has been largely debunked, and WIREDs reporting on Australian academic Craig Wright, who has claimed to be Nakamoto but been unable to prove it.

For all of Bitcoin's success, it hasn't lived up to Nakamoto's dream of a currency for day-to-day transactions, remaining largely a medium for speculators. In part, that's because transactions are incredibly slow. Sirer has estimated that Bitcoin processes around three transactions per second, a poor showing compared to Visas 3,674 transactions per second. Meanwhile, other problems have emerged, such as the Bitcoin network's alarmingly huge carbon footprint, which one report suggests is already on par with that of a small country.

Nakamotos successors on the Bitcoin project, along with the developers of rival cryptocurrencies, are working to solve these problems, but in ways that sometimes radically diverge from the original white paper. The Bitcoin project is considering an innovation called the Lighting Network that would speed up transactions by moving most transactions outside of the blockchain. Sirer, meanwhile, is working on new protocols that address both speed and environmental impact. Others have created new cryptocurrencies that try to address a whole host of Bitcoin issues, from performance to privacy.

"Technically, Satoshi has been outclassed in every imaginable way," Sirer says. "And for the issues we still face, [Satoshis writing] provides no solution."

That led Sirer to declare on Twitter in June that "Satoshi is dead." Sirer didn't mean that literally, but in the sense that Nietzsche wrote that "God is dead": Even Satoshi wouldn't be able to resolve the sorts of disputes the cryptocurrency community now faces.

Jonathan Sidego, an executive at the hedge fund Numerai agrees with Sirer that Nakamotos paper has little guidance to offer on the problems now facing bitcoin and that the public will interpret Nakamotos writings in different ways.

But that's not to say that Nakamoto or the white paper are irrelevant. "The white paper is definitely worth reading for anyone interested in understanding the concepts that allow blockchains to work," Sidego says. "The paper is short and surprisingly readable, so definitely worthwhile."

Neha Narula, director of the MIT Media Labs Digital Currency Initiative, agrees. Asked during a panel at WIRED's 25th anniversary event what what one book or paper on cryptocurrency she'd recommend everyone read, Narula picked the white paper. "It's amazing how the white paper still holds up," she says. "It's still the best way to understand how bitcoin works."

She also thinks that Nakamotos subsequent silence is a big part of the Bitcoin creators legacy.One of the coolest things about Bitcoin is that the creator stepped away, she says. So many people feel like they have ownership over this thing. I think if the person who created it, who started it, was still around, people wouldn't feel like they could have a piece of it too.

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Satoshi Nakamoto Introduced Bitcoin 10 Years Ago ...

How bitcoin has failed to achieve Satoshi Nakamotos …

Bitcoin was created as an alternative payment system, one that operated anonymously and peer-to-peer, eliminating the so-called trusted third party.

But a decade later and the solution proposed by Satoshi Nakamoto, the pseudonym affiliated with the person or persons who created bitcoin BTCUSD, -0.01% is anything but a solution, according to Morgan Stanley researchers.

In a 65-page report outlining bitcoins rapidly morphing thesis, the U.S. banking giant said the worlds largest cryptocurrency is now better categorized as a new institutional investment class and not digital cash, or a replacement payment system, like the early cryptographers intended.

Read: Bitcoin is 10 years old: Heres what to expect in the cryptocurrencys second decade

Technology headwinds, such as scalability and security, have hindered its ability to operate as a sustainable payment system. In other words, bitcoin and its ilk havent been widely adopted and many observers still fear that the digital apparatus around such virtual assets can safeguard their currency holdings.

The high costs of operating a fully trustless system is pushing early players to Balkanize systems into trusted blockchains/distributed ledgers, the bank said, adding that it has virtually no acceptance among U.S. e-commerce merchants.

Read: A team at Northwestern think they have solved one of bitcoins biggest problems

Moreover, Morgan Stanley MS, -0.28% said the surge in capital allocation to digital-currency funds is evidence that investors now see the technology as an opportunity to turn a profit, citing a $6.9 billion increase in crypto fund assets under management since January 2016.

Read: The round numbers that show just how far bitcoin has come in 10 years

Furthermore, any hope the 10-year old experiment will achieve its original intent looks to have passed, with questions now revolving around how to raise funds, not improve payments system, according to Morgan Stanley.

A lack of a more formal regulatory structure, which remains in its infancy, also has been cited as an impediment by the Morgan Stanley analysts.

From our client conversations, we find three major obstacles preventing large scale investment in the cryptocurrency space: Underdeveloped regulation so asset managers dont want to take on the reputational risk; lack of a custodian solution to hold the cryptocurrency and private keys; lack of large financial institutions and asset managers currently invested.

Read: This is where cryptocurrencies are actually making a difference in the world

Providing critical information for the U.S. trading day. Subscribe to MarketWatch's free Need to Know newsletter. Sign up here.

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How bitcoin has failed to achieve Satoshi Nakamotos ...

Trance Terra – Final Fantasy Brave Exvius Wiki

A woman who appears in tales from another world, where she played a role in the great conflict between humankind and espers. Able to wield magical powers believed lost to the world, Terra was used as a weapon by the Gestahl Empire bent on world domination. However, she was eventually saved by the treasure hunter Locke and joined him in the fight against the empire by becoming a member of the Returners. Dedicating herself to their cause, she travels with the group to see the esper Valigarmanda, where a strange power resonates with her. In moments, Terra transforms into an esper and flees to an unknown location.

If used after Magical Activation:Magic damage (3.6x) with ignore SPR (50%) to all enemies

10Frame delay: 60-8-8-8-8-8-8-8-8-8Attack frames: 60-68-76-84-92-100-108-116-124-132

0

If used after Magical Activation:Magic damage (4.2x) with ignore SPR (50%) to all enemies

10New frame delay: 60-8-8-8-8-8-8-8-8-8New attack frames: 60-68-76-84-92-100-108-116-124-132

0

If used after Magical Activation:Magic damage (4.2x) with ignore SPR (50%) to all enemiesGain access: Chaos Wave Awakened +2

10New frame delay: 60-8-8-8-8-8-8-8-8-8New attack frames: 60-68-76-84-92-100-108-116-124-132

0

Gameplay

Trivia

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Trance Terra - Final Fantasy Brave Exvius Wiki

Bitcoin Price Index – Real-time Bitcoin Price Charts

XRP Nears 50 Cents as Price Rises to One-Month Highs

Nov 6, 2018 at 01:01 | Sebastian Sinclair

XRP, the world's third-largest cryptocurrency by market capitalization, jumped 6 percent on Monday, cementing a 30-day high.

Nov 5, 2018 at 17:00 | David Floyd

Last week's much-scrutinized letter, in which a Bahamas-based bank appeared to vouch for Tether's balance, has been confirmed as genuine by the bank.

Nov 5, 2018 at 13:00 | Michael J Casey

What happens if there's another 2008-scale financial market crisis? Will diehard HODLers still resist liquidating their bitcoin assets?

Nov 5, 2018 at 11:00 | Omkar Godbole

Bitcoin could be about to make a move towards $6,800, having witnessed a bullish triangle breakout yesterday.

Nov 2, 2018 at 13:01 | Anna Baydakova

Blockchain startup AlphaPoint has hired Kapil Rathi from Cboe Global Markets, the parent of the Chicago Board of Exchange.

Nov 2, 2018 at 11:00 | Omkar Godbole

A trendline rising from 2011 lows has become the level to beat for the bitcoin bears.

Nov 1, 2018 at 22:00 | Leigh Cuen

Unlike its parent company, Binance Uganda handles fiat currency (in partnership with a local mobile payment provider) and requires full customer ID.

Nov 1, 2018 at 20:45 | Sam Ouimet

The price of dogecoin fell over 36 percent in October, making it the worst performer out of the world's 25 largest cryptocurrencies.

Nov 1, 2018 at 12:30 | Yogita Khatri

Crypto exchange Bithumb has teamed up with crowdfunding platform seriesOne to launch a compliant security token exchange in the U.S.

Nov 1, 2018 at 11:21 | Omkar Godbole

Bitcoin ended October on a weak note, confirming its first three-month losing streak since 2015, but things may be looking up for November.

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Bitcoin Price Index - Real-time Bitcoin Price Charts

Human Genetics – McGraw-Hill Education

Introduction

C H A P T E R 1

What Is in a Human Genome?

C H A P T E R 2

Cells

C H A P T E R 3

Meiosis, Development, and Aging

P A R T 2

Transmission Genetics

C H A P T E R 4

Single-Gene Inheritance

C H A P T E R 5

Beyond Mendels Laws

C H A P T E R 6

Matters of Sex

C H A P T E R 7

Multifactorial Traits

C H A P T E R 8

Genetics of Behavior

P A R T 3

DNA and Chromosomes

C H A P T E R 9

DNA Structure and Replication

C H A P T E R 10

Gene Action: From DNA to Protein

C H A P T E R 11

Gene Expression and Epigenetics

C H A P T E R 12

Gene Mutation

C H A P T E R 13

Chromosomes

P A R T 4

Population Genetics

C H A P T E R 14

Constant Allele Frequencies and DNA Forensics

C H A P T E R 15

Changing Allele Frequencies

C H A P T E R 16

Human Ancestry and Evolution

P A R T 5

Immunity and Cancer

C H A P T E R 17

Genetics of Immunity

C H A P T E R 18

Cancer Genetics and Genomics

P A R T 6

Genetic Technology

C H A P T E R 19

DNA Technologies

C H A P T E R 20

Genetic Testing and Treatment

C H A P T E R 21

Reproductive Technologies

C H A P T E R 22

Genomics

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Human Genetics - McGraw-Hill Education

Human genetic disease | Britannica.com

About 1 out of 150 live newborns has a detectable chromosomal abnormality. Yet even this high incidence represents only a small fraction of chromosome mutations since the vast majority are lethal and result in prenatal death or stillbirth. Indeed, 50 percent of all first-trimester miscarriages and 20 percent of all second-trimester miscarriages are estimated to involve a chromosomally abnormal fetus.

Chromosome disorders can be grouped into three principal categories: (1) those that involve numerical abnormalities of the autosomes, (2) those that involve structural abnormalities of the autosomes, and (3) those that involve the sex chromosomes. Autosomes are the 22 sets of chromosomes found in all normal human cells. They are referred to numerically (e.g., chromosome 1, chromosome 2) according to a traditional sort order based on size, shape, and other properties. Sex chromosomes make up the 23rd pair of chromosomes in all normal human cells and come in two forms, termed X and Y. In humans and many other animals, it is the constitution of sex chromosomes that determines the sex of the individual, such that XX results in a female and XY results in a male.

Numerical abnormalities, involving either the autosomes or sex chromosomes, are believed generally to result from meiotic nondisjunctionthat is, the unequal division of chromosomes between daughter cellsthat can occur during either maternal or paternal gamete formation. Meiotic nondisjunction leads to eggs or sperm with additional or missing chromosomes. Although the biochemical basis of numerical chromosome abnormalities remains unknown, maternal age clearly has an effect, such that older women are at significantly increased risk to conceive and give birth to a chromosomally abnormal child. The risk increases with age in an almost exponential manner, especially after age 35, so that a pregnant woman age 45 or older has between a 1 in 20 and 1 in 50 chance that her child will have trisomy 21 (Down syndrome), while the risk is only 1 in 400 for a 35-year-old woman and less than 1 in 1,000 for a woman under the age of 30. There is no clear effect of paternal age on numerical chromosome abnormalities.

Although Down syndrome is probably the best-known and most commonly observed of the autosomal trisomies, being found in about 1 out of 800 live births, both trisomy 13 and trisomy 18 are also seen in the population, albeit at greatly reduced rates (1 out of 10,000 live births and 1 out of 6,000 live births, respectively). The vast majority of conceptions involving trisomy for any of these three autosomes are nonetheless lost to miscarriage, as are all conceptions involving trisomy for any of the other autosomes. Similarly, monosomy for any of the autosomes is lethal in utero and therefore is not seen in the population. Because numerical chromosomal abnormalities generally result from independent meiotic events, parents who have one pregnancy with a numerical chromosomal abnormality are generally not at markedly increased risk above the general population to repeat the experience. Nonetheless, a small increased risk is generally cited for these couples to account for unusual situations, such as chromosomal translocations or gonadal mosaicism, described below.

Structural abnormalities of the autosomes are even more common in the population than are numerical abnormalities and include translocations of large pieces of chromosomes, as well as smaller deletions, insertions, or rearrangements. Indeed, about 5 percent of all cases of Down syndrome result not from classic trisomy 21 but from the presence of excess chromosome 21 material attached to the end of another chromosome as the result of a translocation event. If balanced, structural chromosomal abnormalities may be compatible with a normal phenotype, although unbalanced chromosome structural abnormalities can be every bit as devastating as numerical abnormalities. Furthermore, because many structural defects are inherited from a parent who is a balanced carrier, couples who have one pregnancy with a structural chromosomal abnormality generally are at significantly increased risk above the general population to repeat the experience. Clearly, the likelihood of a recurrence would depend on whether a balanced form of the structural defect occurs in one of the parents.

Even a small deletion or addition of autosomal materialtoo small to be seen by normal karyotyping methodscan produce serious malformations and mental retardation. One example is cri du chat (French: cry of the cat) syndrome, which is associated with the loss of a small segment of the short arm of chromosome 5. Newborns with this disorder have a mewing cry like that of a cat. Mental retardation is usually severe.

About 1 in 400 male and 1 in 650 female live births demonstrate some form of sex chromosome abnormality, although the symptoms of these conditions are generally much less severe than are those associated with autosomal abnormalities. Turner syndrome is a condition of females who, in the classic form, carry only a single X chromosome (45,X). Turner syndrome is characterized by a collection of symptoms, including short stature, webbed neck, and incomplete or absent development of secondary sex characteristics, leading to infertility. Although Turner syndrome is seen in about 1 in 2,500 to 1 in 5,000 female live births, the 45,X karyotype accounts for 10 to 20 percent of the chromosomal abnormalities seen in spontaneously aborted fetuses, demonstrating that almost all 45,X conceptions are lost to miscarriage. Indeed, the majority of liveborn females with Turner syndrome are diagnosed as mosaics, meaning that some proportion of their cells are 45,X while the rest are either 46,XX or 46,XY. The degree of clinical severity generally correlates inversely with the degree of mosaicism, so that females with a higher proportion of normal cells will tend to have a milder clinical outcome.

In contrast to Turner syndrome, which results from the absence of a sex chromosome, three alternative conditions result from the presence of an extra sex chromosome: Klinefelter syndrome, trisomy X, and 47,XYY syndrome. These conditions, each of which occurs in about 1 in 1,000 live births, are clinically mild, perhaps reflecting the fact that the Y chromosome carries relatively few genes, and, although the X chromosome is gene-rich, most of these genes become transcriptionally silent in all but one X chromosome in each somatic cell (i.e., all cells except eggs and sperm) via a process called X inactivation. The phenomenon of X inactivation prevents a female who carries two copies of the X chromosome in every cell from expressing twice the amount of gene products encoded exclusively on the X chromosome, in comparison with males, who carry a single X. In brief, at some point in early development one X chromosome in each somatic cell of a female embryo undergoes chemical modification and is inactivated so that gene expression no longer occurs from that template. This process is apparently random in most embryonic tissues, so that roughly half of the cells in each somatic tissue will inactivate the maternal X while the other half will inactivate the paternal X. Cells destined to give rise to eggs do not undergo X inactivation, and cells of the extra-embryonic tissues preferentially inactivate the paternal X, although the rationale for this preference is unclear. The inactivated X chromosome typically replicates later than other chromosomes, and it physically condenses to form a Barr body, a small structure found at the rim of the nucleus in female somatic cells between divisions (see photograph). The discovery of X inactivation is generally attributed to British geneticist Mary Lyon, and it is therefore often called lyonization.

The result of X inactivation is that all normal females are mosaics with regard to this chromosome, meaning that they are composed of some cells that express genes only from the maternal X chromosome and others that express genes only from the paternal X chromosome. Although the process is apparently random, not every female has an exact 1:1 ratio of maternal to paternal X inactivation. Indeed, studies suggest that ratios of X inactivation can vary. Furthermore, not all genes on the X chromosome are inactivated; a small number escape modification and remain actively expressed from both X chromosomes in the cell. Although this class of genes has not yet been fully characterized, aberrant expression of these genes has been raised as one possible explanation for the phenotypic abnormalities experienced by individuals with too few or too many X chromosomes.

Klinefelter syndrome (47,XXY) occurs in males and is associated with increased stature and infertility. Gynecomastia (i.e., partial breast development in a male) is sometimes also seen. Males with Klinefelter syndrome, like normal females, inactivate one of their two X chromosomes in each cell, perhaps explaining, at least in part, the relatively mild clinical outcome.

Trisomy X (47,XXX) is seen in females and is generally also considered clinically benign, although menstrual irregularities or sterility have been noted in some cases. Females with trisomy X inactivate two of the three X chromosomes in each of their cells, again perhaps explaining the clinically benign outcome.

47,XYY syndrome also occurs in males and is associated with tall stature but few, if any, other clinical manifestations. There is some evidence of mild learning disability associated with each of the sex chromosome trisomies, although there is no evidence of mental retardation in these persons.

Persons with karyotypes of 48,XXXY or 49,XXXXY have been reported but are extremely rare. These individuals show clinical outcomes similar to those seen in males with Klinefelter syndrome but with slightly increased severity. In these persons the n 1 rule for X inactivation still holds, so that all but one of the X chromosomes present in each somatic cell is inactivated.

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Human genetic disease | Britannica.com

Cyborg | Brickipedia | FANDOM powered by Wikia

CyborgVariations:

New 52, Justice League, Rebirth

Cyborg (a.k.a. Victor Stone) is a Super Heroes minifigure who first appears in LEGO Batman 2: DC Super Heroes, LEGO Batman: The Movie DC Super Heroes Unite, and LEGO Batman 3: Beyond Gotham. He was physically released in the set 76028 Darkseid Invasion in 2015.

Cyborg's head has dark skin, his right half has short black hair and left half is covered by silver plating with red eyes. He has a silver torso with part of his chest exposed and a red circle in the center of his chest, which is covered by silver plating and machinery. His arms are also printed,with part of his skin exposed, and his legs and hips are also silver and covered up with machinery.

Cyborg has dark skin, with the right half of his face being left unotuched by the machinery. He has short, black hair. The left side of his face is covered by a silver helmet with extends around his chin and on his cheeks on the right half of his face. The mask has a red, glowing eye and a small, red circle on the forehead. Cyborg's face has two expressions, one confident and one angry. Cyborg's torso is black with the details of his armor, and his arms are pearl silver. The suits' armored details continue down Cyborg's legs, which are also pealr silver.

In LEGO Batman 2: DC Super Heroes, Cyborg is magnetic, able to activate machinery, and shoot lasers from his artificial eye. He is unlocked for free-play after the level "Tower Defiance" is completed and is also playable in the story-mode of "Heroes Unite".

On the portable versions of the game, Cyborg is a playable character in Story Mode of the level "Wayne Industries". His minikit can be found on the same level, and he costs 100,000 studs. In the portable version, Cyborg has different torso and leg printing.

Half of Victor Stone's body was destroyed in a tragic accident. He was saved through experimental technology created by his father Silas, and his body parts were replaced with high-tech gadgets and weaponry. To have Vic around people who may understand his condition, Silas asked the Titans to accept Vic among them as Cyborg, and in exchnage Silas built a T-shaped tower as the Titans' new headquarters.

He is a member of the Justice League, which mainly consists of Superman, Batman, the Flash, Green Lantern, Wonder Woman, Martian Manhunter, Aquaman, and on some occasions Nightwing, Batgirl, and Huntress. He was also a member of the Teen Titans, with notable members consisting of Nightwing, Miss Martian, Blue Beetle, Superboy, Kid Flash, Roy Harper, Tempest, Troia, Raven, Starfire and Beast Boy, who is also Cyborg's best friend.

In LEGO Batman 2: DC Super Heroes, Cyborg is a member of the Justice League. He is one of the members being monitored by The Martian Manhunter when he checks in on Bruce Wayne.

Later, when Lex Luthor and the Joker attacked Wayne Tower with their Kryptonite powered mech, Cyborg, Batman, Robin, and Green Lantern entered through the bottom of the destroyed tower while Superman and Wonder Woman held it in place. When Green Lantern used a train construct to knock the robot off of the building, Cyborg and the others dove off the edge after it and fought with The Joker. When the robot was defeated, Green Lantern created an elevator and lowered the heroes unable to fly to safety. The Flash and Green Lantern repaired the tower, relieving Superman and Wonder Woman. Cyborg then joined Batman, Robin, Wonder Woman, Green Lantern, The Flash, and Martian Manhunter (from the Watchtower) in destroying what was left of the robot, fought with and defeated Joker again, and then tried to avoid Luthor's weaponry from his back-up mech until Robin and Manhunter could target the Watchtower's cannon long enough to destroy it.

Cyborg teams up with other DC superheroes to save the world from Brainiac. Cyborg, just like Batman, Robin, Lex Luthor, and the Joker has a wide selection of new suits to help out with stopping Brainiac.

His LEGO Dimensions Figure

Cyborg with the Justice League

Portable Version Back Printing

Cyborg in the new justice league sets

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Cyborg | Brickipedia | FANDOM powered by Wikia

Cris Cyborg – Official UFC Fighter Profile

When and why did you start training for fighting? Istarted training over a decade ago. I was always an athlete, and once Idiscovered that unlike handball, MMA doesn'tissue red cards, I knew I had found my true sport.

What ranks and titles have you held? UFC Womens Featherweight Champion. Former Invicta FCWorldChampion. FormerStrikeforce World Champion. 2x IBJJF World Champion. ADCC Bronze Medalist.

Do you have any heroes? Jesus Christ, who died for our sins.

What does it mean for you to fight in the UFC? It is anhonor.

Did you go to college and if so what degree did you earn? I never finished university; however, it issomethingI plan to return to once my MMA career isfinished. Animals are a passion for me and I think it would be amazing to one day further my knowledge and find a way to work with them.

What was your job before you started fighting? I used to work inside of a pet grooming store.

Ranks in any martial arts styles: Chute Boxe Muay Thai black belt, Brazilian Jiu-Jitsu brown belt under Andre Galvao of Atos BJJ TeamFavorite grappling technique: SuplexFavorite Striking technique: Whatever strikefinishes with a KO

17 wins by KO, three by decision

Lost pro debut unbeaten since

10 first round finishes

Has won 10 straight

Had 4-0, 1 NC record in Strikeforce

Was 5-0 with five finishes in Invicta FC

Owns wins over Gina Carano, Marloes Coenen (twice), Shayna Baszler and Vanessa Porto

Has finished 13 of last 14 wins

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Cris Cyborg - Official UFC Fighter Profile

About | Pantheism.com

Etymology: pan[Greek ] + theos[Greek] = ALL is GOD

Pantheism: Everything is Connected, Everything is Divine

Pantheism essentially involves two assertions: that everything that exists constitutes a unity and that this all-inclusive unity is divine. Alasdair MacIntyre, Encyclopedia of Philosophy, Pantheism 1971

The belief in or perception of Divine Unity Michael Levine,Pantheism: A non-theistic concept of deity

Pantheism the belief in the divine unity of all things is consistent with some of the earliest recorded human thought. But modern day pantheism goes well beyond the wonder of our pre-historic ancestors. Today, it is much more a tangible resultant of the action and reaction between Science and Religion than the ghost of speculations past. Discover the history of Pantheism, from 3500 year old Vedic poetry to our current scientific quest for a Theory of Everything, here.

Pantheism.com is an educational site, providing information, news, groups, and connections. Celebrate your views, discuss the nature of Nature, learn about the history and flavors of Pantheism (there are many!), find or start a local event, and in general, hang out with fellow freethinkers and travelers. Click to learn more about the people who keep the lights on around here.

Organizations:

Universal Pantheist Society, est. 1975 by Harold Wood

World Pantheist Movement, est. 1998 by Paul Harrison

Ayahuasca Pantheist Society, est. 2003 byRegis A. Barbier

The Paradise Project, est. 2004 byPerry Rod

Spiritual Naturalist Society, est. 2012 by DT Strain

Biopantheism, by Poffo Ortiz

Panmeism, by Guyus Seralius

Not Two, by Waldo Noesta

Fays of Life, by Fay Campbell

Evolution of Consent, by William Schnack

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About | Pantheism.com

What is pantheism? | CARM.org

by Matt Slick

Pantheism is the position that God and nature are the same thing. Pantheism comes from two Greek words, pan meaning all and theos meaning 'god.' So, it would teach that all the stars, galaxies, planets, mountains, wind, and rain, are all one and the same... part of what God is. So, pantheists would say that all is God.

Biblical Christianity teaches that God is separate from his creation and he created it (Gen. 1:1-30), where pantheism says that Godand creation share the same nature and essence.

A huge problem with pantheism is that it cannot account for the existence of the universe. The universe is not infinitely old. It had a beginning. This would mean that God also had a beginning, buthow can something bring itself into existence? This is impossible, so this leaves us with the question of where God and the universe came from. Pantheism cannot answer this question, and it naturally leads to absurdities.

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What is pantheism? | CARM.org

Tweaking Coal Plant Emissions Could Slow Down Climate Change

Another Scorcher

This past year brought an onslaught of horrifying weather, from droughts and fires in California to devastating storms around the world. If we keep powering our world with fossil fuels, scientists believe, these extreme weather events are going to get worse.

New research published Wednesday in Science Advances suggests there may be a way to slow down our climate change apocalypse, giving us a little bit more time to transition to clean, renewable energy.

Brain Melting

The research project, conducted in part by prominent Penn State earth scientist Michael Mann, explored models that predicted anywhere from a slight decline to a tripling in what are called quasi-resonant amplification (QRA) events.

These QRA events happen when jet streams — global wind patterns, basically — are disrupted and pockets of hot and cold air get stuck in place. They’re directly linked to extreme weather events like droughts and storms.

With business-as-usual dependence on coal and oil,the research suggestswe’re likely going to see a 50 percent increase in QRA events — therefore also dangerous weather — during the 21st century.

Clean Coal

These jet stream disruptions are caused by aerosols, which are released into the atmosphere by burning coal. If coal-burning plants adopt technology to help filter out the aerosols as they burn coal, the worst of climate change-driven weather could be delayed until the middle of the century.

It’s far from a solution, but the finding could give us a slightly longer window to adopt clean energy around the world. If we don’t, the worst of those climate models will almost certainly become reality.

READ MORE: Controlling future summer weather extremes still within our grasp [Penn State News]

More on alternative fuels: Clean Coal Startup Turns Human Waste into Earth-Friendly Fuel

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Tweaking Coal Plant Emissions Could Slow Down Climate Change

Glimpse: Utopian Fiction Could Help Us Unlock the Bright Future We Never Imagined

We live in an age in which fact can seem stranger than fiction. From the climate to finance to our political systems, it feels like we’re at an inflection point in history where truly anything could happen. Nothing seems harder to predict than the future.

Maybe that’s why dystopian narratives have become so popular.  We’re hooked on shows like West World, The Handmaid’s Tale, and Black Mirror. Several studies have found that millennials — a demographic that will make up nearly half the workforce by 2020, and the primary audience for shows like Black Mirror — are one of the most cynical generations in modern history.

It makes sense. Dystopian shows can help us work through possible (or even plausible) realities. “Writing dystopias and utopias is a way of asking readers: where do you want to live?” Margaret Atwood said at the 2018 Women in the World Summit.

But cynicism and distrust can be damaging, too. Feeling like the nail is already in our proverbial collective coffin can discourage people who might be able to fix society’s ills.

This is all addressed in the final episode of Glimpse, a new original sci-fi series from Futurism Studios (a division of Futurism LLC) and DUST. Watch the episode below.

Indeed, these dystopian tales are only half the story. The technologies that will power the future — artificial intelligence, genome editing, advanced robotics, blockchain — are not innately good or evil. We need people who will use them for good. Our fate, as a civilization, as a species, hasn’t been decided yet. If we’re smart, and if we’re diligent, and if we’re motivated, we can create a happy ending for ourselves.

Image Credit: Getty Images

Utopian fiction plays a role in getting us there. The way dystopian narratives can caution, optimistic ones can inspire. They could bring new uses for technology we already have, and maybe even tools no one has come up with yet.

In fact, optimistic stories played a key role in one of the United States’ biggest achievements. In October 1951, at the dawn of the space race, the United States held the First Symposium on Space Flight. The event, held at American Museum of Natural History’s Hayden Planetarium in New York City, was “one of the keys in introducing the U.S. public to the idea that human space flight was a serious possibility,” according to NASA. There were speakers and journalists in attendance, and major media outlets like Collier’s Magazine and Disney created educational materials (as well as science fiction stories) that walked through hypotheticals about how humans would survive and thrive outside Earth’s atmosphere. When President John F. Kennedy Jr made has famous Moonshot speech a decade later, the public was already comfortable with the idea of putting a man on the Moon, setting the stage for the once-incomprehensible Apollo 11 mission in 1969.

The way dystopian narratives can caution, optimistic ones can inspire.

Utopian fiction could do the same for today’s moonshots. We want to believe that we can break down barriers, cure persistent diseases, stop the planet from warming, visit new worlds. We just need to be convinced it’s possible.

This is driving force behind Glimpse, Futurism Studios’ first-ever science fiction series. Over the course of eight episodes, we sought to tell positive and engaging stories about the world of tomorrow. We grew babies outside the body, and turned ourselves into cyborgs. We brought back the wooly mammoth, and made language barriers a thing of the past. We created immortal best friends, and broke the hold of VR. We finally even saw augmented reality reach its full potential (it was about darn time).

These episodes may be fiction, but they’re a small insight into the kind of world researchers and innovators are making just a little more possible every day. None of them depict a perfect world, but none are totally far-fetched, either. Utopian fiction isn’t marked by the absence of conflict, but the resolution of it.

So fiction — of the dystopian and optimistic varieties — both have their value. Dystopian stories can be a powerful motivator for societies headed down the wrong path to right themselves. In the same way, utopian fiction illuminates a possible right way forward — the ones that lead to the kind of society we all wanted in the first place.

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Glimpse: Utopian Fiction Could Help Us Unlock the Bright Future We Never Imagined

You’ll Be Able to Buy a Car With a Solar Roof in 2019

Star Power

Get ready to trade in your car’s sunroof for a solar roof.

On Wednesday, automakers Hyundai Motor and Kia Motors jointly announced plans to install electricity-generating solar panels on select vehicles beginning in 2019. According to a press release, the companies will install the panels on the roofs or hoods of their vehicles. They won’t replace the cars’ existing power system, just supplement them.

The companies say they plan to roll out three generations of the solar roof charging systems. They designed the first system for use with hybrid vehicles, the second system for fossil fuel-powered cars, and the third system for fully battery-powered vehicles.

On the Path

The solar roofs are just the beginning of the automakers’ plans to make their vehicles more green.

“In the future, we expect to see many different types of electricity-generating technologies integrated into our vehicles,” said Hyundai Motor Group executive Jeong-Gil Park. “The solar roof is the first of these technologies, and will mean that automobiles no longer passively consume energy, but will begin to produce it actively.”

So, while we might not yet be able to buy the fully solar-powered car of our dreams, we can at least get one step closer in 2019.

READ MORE: Hyundai, Kia Hope to Add Solar Panel Charging Tech to Cars in 2019 [Road Show]

More on solar cars: A Fully Solar-Powered Car May Be Hitting the Road by 2019

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You’ll Be Able to Buy a Car With a Solar Roof in 2019

The Island Nation Malta Created a Citizenship Test for Robots

Citizen K(AI)ne

Malta, a tiny European island nation, is preparing for a future in which robots and humans coexist side by side as fellow citizens.

In a partnership with SingularityNET, the decentralized AI research hub that designed Sophia the robot’s software, the Malta Digital Innovation Authority just drafted a citizenship test for robots — should they ever become advanced enough for that to be relevant.

New Kid on the Block

Malta recently made headlines for embracing financial blockchain technology, and the new preparations for robot citizenship are part of the government’s push to further cement its place as a technological world leader.

The push includes drafting a national strategy and task force for developing artificial intelligence that’s safe, ethical, and beneficial to the people of Malta. Few nations have taken the time to develop thoughtful guidelines around AI — the U.S., for instance, tends to dive into new tech headfirst without pondering ethical qualms or potential harms it could do.

Act of ’53

Saudi Arabia granted citizenship to Sophia the robot last year, in a move that experts critiqued as a stunt. Nowhere in the world — not in Malta, not anywhere else — is there a robot or an AI system advanced enough to act like a person. That level of technology is far in the future and we have no idea how to get there.

That being said, someone has to find answers to the many moral, ethical, and philosophical questions that advanced AI will bring — and Malta’s task force is putting the small island in position to take charge.

READ MORE: Watch: Malta mulling citizenship for robots [Times Malta]

More on Malta: Malta Plans to Create the World’s First Decentralized Stock Exchange

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The Island Nation Malta Created a Citizenship Test for Robots

MDMA Therapy Eliminated PTSD Symptoms In 76 Percent of Patients

Chill Pill

Some researchers are starting to believe MDMA, the party drug commonly known as “ecstasy” or “molly,” could become a recognized treatment for post-traumatic stress disorder (PTSD) in the coming years.

Case in point: A small clinical trial published last week in the Journal of Psychopharmacology found that therapeutic doses of MDMA, in concert with psychotherapy, reduced the severity of most participants’ PTSD symptoms. And a year after the trial ended, 76 percent of participants no longer met the clinical criteria for a PTSD diagnosis.

Expect Delays

The results, as exciting as they seem on paper, are only from a phase II trial — the second of three stages of safety and efficacy testing required before the U.S. Food and Drug Administration will consider approving a new pharmaceutical.

Many phase II trials, this one included, gather very impressive-sounding results, but the road to FDA approval is littered with the corpses of early-stage research that never made it to the end. That said, phase III trials for treating PTSD with MDMA are underway.

Solid Science

Aside from its small sample size of only 28 participants, the National Institutes of Health (NIH)’s website for monitoring clinical research shows no methodological red flags.

Even so, MDMA is still listed as a schedule one drug, which means the government prevents it from being legally  prescribed, believes it has a high risk of abuse, and won’t recognize clinical uses. Though FDA approval would help change that, it means MDMA cannot legally be prescribed off-label in the meantime.

But if all goes well in follow-up research, it’s conceivable that MDMA treatments could hit the market after phase III trials are completed, which is expected to happen within three years.

READ MORE: MDMA therapy achieves astounding 76% success rate for treating PTSD [New Atlas]

More on PTSD treatment: The FDA Has Labeled Ecstasy A “Breakthrough Therapy” for PTSD

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MDMA Therapy Eliminated PTSD Symptoms In 76 Percent of Patients

Mars Used To Be Dotted With Life-Friendly Lakes

Water Everywhere

Where there’s water, there’s usually life — at least on Earth — and we just got confirmation that there used to be far more water on the surface of Mars than scientists previously believed.

The news comes courtesy of a team of researchers from the SETI Institute and NASA’s Ames Research Center. They’ve identified dozens of potential “paleolakes” — lakes that existed when the climate of a region was different than it is today — in the southern hemisphere of Mars. And the finding could forever change the hunt for extraterrestrial life.

On the Map

We already knew of one potential paleolake located in the northeastern part of Hellas, a massive basin in the southern hemisphere of Mars. In a study published in the journal Astrobiology on Tuesday, the researchers detail their discovery of 33 more.

The team conducted a detailed hydrogeographic analysis of the region, mapping its channels and depressions to suss out where additional Martian lakes may have once existed. This turned up the 33 new paleolakes.

By looking at each paleolake’s distinct characteristics, the team was even able to identify its most probable source of water: precipitation, groundwater, or rivers and streams.

Life on Mars

The discovery of these paleolakes is about more than just mapping the geology of Mars. It could also inform our search for life on the Red Planet.

As the researchers note in the paper, the former Martian lakes could contain the biological record of what, if any, life once existed on the planet, so as we plan future missions to Mars, we might want to consider devoting significant time to exploring this once-wet region of its surface.

READ MORE: Groundwater and Precipitation Provided Water to Form Lakes Along the Northern Rim of Hellas Basin Throughout Mars’s History [SETI Institute]

More on Mars: We Just Found New Evidence of Water on Mars

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Mars Used To Be Dotted With Life-Friendly Lakes

Musk: Tesla Pickup Truck Will Be Straight Out of “Blade Runner”

Truckin’

While sports car enthusiasts are salivating over the Tesla Roadster’s record-shattering performance — 0 to 60 in under two seconds is no joke — Tesla CEO Elon Musk is more excited about a very different Tesla.

“Actually, I’m personally most excited about the pickup truck,” Musk admitted to Recode in an interview this week. “Well I can’t talk about the details, but it’s gonna be like a really futuristic-like cyberpunk, ‘Blade Runner’ pickup truck.”

Pick Me Up

Details are still sparse, but Musk’s enthusiasm for the pickup truck in particular really comes through. He’s been tweeting about it since at least December of last year, but the idea has been around since at least November 2013. He unveiled an image of the truck in 2017 that Jalopnik called “ridiculous.”

Before the pickup truck, Tesla is expected to release the Model Y — a hopefully as-futuristic SUV.

Country, Buds, and Superchargers

The prospect of a utility truck that doesn’t rely on chugging gasoline or diesel is exciting, and we can’t wait to see what Tesla’s “futuristic” design will end up looking like.

And he doesn’t even care if it doesn’t sell at all.

“You know, I actually don’t know if a lot of people will buy this pickup truck or not,” he told Recode, “but I don’t care.”

READ MORE: Elon Musk: The Recode interview [Recode]

More on the Tesla pickup truck: An Electric Pickup Truck Will Be Tesla’s Top Priority After the Model Y

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Musk: Tesla Pickup Truck Will Be Straight Out of “Blade Runner”

New AI Thinks Like a Scientist to Explain the Physics of Virtual Worlds

Albert AI-nstein

One of the big challenges for artificial intelligence developers is building a system that can interpret and understand the world around it — just look at how long it’s taking to build capable self-driving cars.

To probe that challenge, MIT physicists Max Tegmark and Tailin Wu generated a series of simulated worlds in which a ball bounced through areas affected by gravitational and electric fields, according to MIT Technology Review. They fed that data into a custom-built AI system and tasked it with figuring out the physics of these virtual worlds.

In the end, according to research published to the preprint server ArXiv last week, they got an algorithm that can learn about its environment using tricks similar to the scientific method.

AI-saac Newton

Most machine learning algorithms tend to make sense of the data on which they’re trained via broad, overarching rules and assumptions.

This new “AI Physicist,” as Tegmark and Wu have called it, can compartmentalize what its training data has told it. This preference for simplicity gives the AI Physicist the ability to create distinct theories about the physical environment, loosely based on different branches of physics. That means it could learn how both mechanics and electromagnetism work at the same time, for example.

Richard F-AI-nman

It’s possible, as MIT Technology Review suggested, that tools like the AI Physicist could help take over some aspects of scientific research. Machine learning systems excel at finding patterns and making predictions, and is most useful when poring over more data and finding more obscure correlations than a human would ever be able to.

With an algorithm that can simplify and streamline its findings, not unlike a digital Occam’s Razor, research labs across all kinds of science may soon spot new discoveries that humans could have been overlooking for years.

READ MORE: An AI physicist can derive the natural laws of imagined universes [MIT Technology Review]

More on advanced AI: New Artificial Intelligence Does Something Extraordinary — It Remembers

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New AI Thinks Like a Scientist to Explain the Physics of Virtual Worlds