Medicine in motion: How Tai Chi heals body and mind – CNN

"It is the most unbelievable, beautiful, harmonious, blissful exercise," Fung says, as she lifts her arms to the sky in the preparatory movement called Wu Chi.

"We breathe in, we open palms down, absorb the energy from Earth. We breathe in, palms up towards the sky, absorb the energy from heaven," she explains, bringing a dancer's innate elegance to the motions.

It was dance that brought Fung to the practice of Tai Chi, as she searched for ways to heal multiple injuries she sustained as she practiced her craft.

"As a ballerina, you always strive harder to break through the limits," Fung said. "Your body is getting sick and is injured all the time.

"Why Tai Chi has good, amazing health benefits is because it's a self-healing process." she said. "When I started, I thought, 'This is quite phenomenal.'"

A balance of yin and yang

Evolving from ancient martial arts, the core principles of Tai Chi are based on Taoism, an ancient Chinese philosophy which stresses a natural balance between two opposing forces called yin and yang.

Think of yin and yang as the complementary but opposite sides of a coin that together form a perfect whole.

"Yang is your mind, it's a cerebral activity. It's your emotions. Yin is your body," Fung said. "By practicing Tai Chi, you connect these two parts, and you balance the yang energy with the yin energy."

"When these two things balance, then harmony is achieved," she continued. "When harmony is achieved, then transformation follows. And the transformation is -- you feel better."

When you are in balance you feel your "chi" or life force which traditional Chinese medicine considers a form of energy that can heal mind and body. When chi is unlocked and flowing through the body, Fung said, it can address the body's injuries.

"When the chi actually start working, your body improves. Your balance gets better. You sleep better. You have enhanced vitality, energy," said Fung, who now teaches classes in Hong Kong combining dance and Tai Chi. "And it keeps flowing. That's why it's amazing."

Science behind the mystery

While all that sounds rather mystical, science shows Tai Chi can improve health. Researchers have discovered that even a shorter, modified exercise series of Tai Chi movements can improve muscle strength, balance and flexibility, while also reducing stress and lowering blood pressure.

Tai Chi also reduces falls and improves balance in the elderly, and is easier than traditional exercise for some with frail health or physical limitations.

Cardiovascular disease: Tai Chi and Qigong, a very similar centuries-old system of movement, breathing and meditation, have shown to be extremely beneficial for cardiovascular health.

Mental health: The calming, meditative trance needed to do a Tai Chi series has been shown to greatly reduce anxiety and stress, even lowering levels of cortisol, the stress hormone, in the blood of participants.

A city of healthy elderly

In Hong Kong, where Fung lives, the practice of Tai Chi is common.

In addition to a healthy diet of fish, rice and vegetables, access to green spaces and a lack of crime, experts point to the health benefits of Tai Chi as a reason lifespan has increased in Hong Kong over the last 50 years.

"For women, it is 88 years," said geriatrician Timothy Kwok, a professor at the Chinese University of Hong Kong. "Less in men, it is 82 years."

The health benefits are so impressive the Hong Kong government promotes the practice of Tai Chi by providing free classes.

"All around the parks in Hong Kong, every morning, you have some people just getting groups of people and teaching them how to Tai Chi," Kwok said. "It is all for free."

For Fung, the ancient Chinese movements are a key to self-healing she cannot live without.

"If you understand how it works, you understand the nature, the fundamentals, the inner workings of what Tai Chi is," Fung said," then when you apply it, and when it works, then it's no turning back."

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Medicine in motion: How Tai Chi heals body and mind - CNN

The Daily Biotech Pulse: Positive Adcom Verdict For Merck, Homology Medicine Slips On Mixed Gene Therapy Efficacy Data – Yahoo Finance

Here's a roundup of top developments in the biotech space over the last 24 hours.

Scaling The Peaks

(Biotech stocks hitting 52-week highs on Dec. 17)

Down In The Dumps

(Biotech stocks hitting 52-week lows on Dec. 17)

Stocks In Focus Homology Medicines Reports Mixed Efficacy Data For Gene Therapy To Treat Phenylketonuria

Homology Medicines Inc (NASDAQ: FIXX) announced initial Phase 1/2 data from the pheNIX trial that evaluated its HMI-102 gene therapy in patients with phenylketonuria, with safety data from the Cohort 1 consisting of two patients administered low dose and Cohort 2 consisting one patient administered mid dose, showing that HMI-102 was well tolerated.

The efficacy data was mixed, with the Cohort 1 patients not showing a reduction in phenylalanine through Week 10 and 12. But the patient dosed in Cohort 2 showed a reduction in phenylalanine of 35% and 48% from baseline at Weeks 1 and Week 4, respectively.

The stock fell 21.84% to $17 in after-hours trading.

FTC Files Compliant To Block Illumina's Deal To Buy PacBio

The FTC saidit has authorized an action to block Illumina, Inc.'s (NASDAQ: ILMN) $1.2 billion buy of Pacific Biosciences of California (NASDAQ: PACB). In an administrative complaint, the agency alleged that "Illumina is seeking to unlawfully maintain its monopoly in the U.S. market for next-generation DNA sequencing systems by extinguishing PacBio as a nascent competitive threat."

The administrative trial is set to begin Aug. 18, 2020.

Pacific Biosciences shares declined 7.85% to $4.93 in after-hours trading.

See Also: After Amarin Snags Vascepa Label Expansion, Analyst Says Biopharma An Attractive M&A Target

Merck Keytruda Gets Thumbs Up From Adcom For Bladder Cancer

Merck & Co., Inc. (NYSE: MRK) said the Oncologic Drugs Advisory Committee of the FDA voted 9 to 4 in favor of recommending the company's Keytruda for the treatment of certain patients with high-risk, non-muscle invasive bladder cancer.

The company expects a PDUFA action date of January2020, based on priority review.

Rigel Chief Commercial Officer Quits

Rigel Pharmaceuticals, Inc. (NASDAQ: RIGL) said its chief commercial officer Eldon Mayer has resigned, effective Dec. 23, to pursue an opportunity with an emerging company. The company said it has begun a search for a replacement, and until a new person assumes office, the commercial leadership team will directly report to CEO Raul Rodriguez.

Offerings

Neoluekin priced its previously announced underwritten public offering of 8.925 million shares of its common stock at $8.40 per share. The company expects to generate gross proceeds of about $75 million from the offering. The offering is expected to close on or about Dec. 20.

On The Radar Adcom Meeting

FDA's Oncologic Drugs Advisory Committee will discuss Oncologic Drugs Advisory Committee Epizyme Inc's (NASDAQ: EPZM) NDA for tazemetostat tablets for treating patients with metastatic or locally advanced epithelioid sarcoma not eligible for curative surgery. The briefing document released Monday showed that the FDA, though commending the company for exploring tazemetostat as a potential therapy for epithelioid sarcoma in a biologically rational way, expressed concerns about insufficient evidence to conclude that the investigational drug confers benefits in patients.

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The Daily Biotech Pulse: Positive Adcom Verdict For Merck, Homology Medicine Slips On Mixed Gene Therapy Efficacy Data - Yahoo Finance

Move over men, theres a movement in medicine – KELOLAND.com

SIOUX FALLS, S.D. (KELO) For years, it was mostly men who applied to medical school in South Dakota, but times are changing.

This past year, for the first time in history, there are about the same number of women as men attending the University of South Dakota Sanford School of Medicine.

One doctor in particular has been instrumental in turning those numbers around.

Chandler Jansen is really focused this year. Thats because shes finishing up her last year of med school at the University of South Dakota Sanford School of Medicine.

Really as long as I can remember medicine was what I want to do, I cant really always explain why, but I always felt that drive to medicine, Jansen said.

Stephanie Kazi is a third year med student.

I kind of got my exposure to healthcare working at a nursing home in high school and thats kind of where I saw about the need for caring for individuals in medicine and I decided that was how I wanted to spend my time and kind of devote myself to a career, Kazi said.

Both are part of what appears to be an upward trend in South Dakota; women entering the medical field to become doctors.

For more than six decades, enrollment at USDs Sanford School of Medicine had been dominated by men. In fact, in all the graduating classes seen here, most of the students were men.

Women were not applying to medical school and we think that might be because women might have been told that, well if you want a family, dont go into a high powered career if you want children, Dr. Mary Nettleman, Dean of Sanford School of Medicine said.

Dr. Mary Nettleman, Dean of Sanford School of Medicine, has been instrumental in getting more women to apply to med school.

We dont create an advantage for somebody, right, we just try to remove barriers if we see them, Dr. Nettleman said.

She says for the longest time women didnt think they could take maternity leave if they were attending medical school. Dr. Nettleman introduced several programs to help young women become doctors.

We have a wellness program, we have pregnancy program, whereby you can get a woman, who gets pregnant during medical school, can have their baby, graduate on time, and take maternity leave, Dr. Nettleman said.

The students will not be penalized for missing any classes, clinics, or assignments because of maternity leave. Instead, the school will work with the student to create an academic makeup plan to ensure that missed course work is completed.

It takes a lot of time, resident Anna Bahnson said.

Anna Bahnson has completed med school and is now in her residency. Even though, she hasnt started a family, she has seen how the school has helped other students find balance between homework and family.

I think a lot of people are intimidated by the time commitment, but I think, you know, no matter what, once you graduate from college or high school or whatever, you know, the next phase is is work, and youre either, working in your job or you if youre in medicine, I think of medical school as, it was my job, Bahnson said.

Dean Nettleman, from the first year of school she gave us talks about that and how we had any, you know concerns that we could come to her and just kind get that process going if we didnt want to get started on, Kazi said.

These are high achieving young people in South Dakota. Theyre going to have a high achieving job. And anytime you do that, you have to balance your family, and your professional life. And its just as important to do that as a physician, as being a school teacher as being any one of them. Its something you just have to do. So we did that and now the class is about 48% women, Dr. Nettleman said.

You heard right, nearly half of all medical students now at USDs Sanford Medicine of Health are women.

Now as these three women look back at the past, they can already picture their future.

If its what youre passionate about follow it, theres always going to be challenges, no matter what career you go into theres always any time commitment. I mean thats not unique to the field of medicine so I wouldnt say being scared of Oh, is this going to take too much time because if youre passionate about it you can find a way to make it work, Jansen said.

For her efforts, Dr. Nettleman has been awarded the prestigious Elizabeth and Emily Blackwell Award for Oustanding Contributions to Advancing the Careers of Women in Medicine.

The award is only given to one doctor in the entire country.

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Move over men, theres a movement in medicine - KELOLAND.com

Class of 2019: From Military to Medicine, Grad Discovers His Life’s Duty – University of Texas at Dallas

Text size: students

Dec. 19, 2019

Editors Note: Every Comet follows a distinct path to UTDallas, and members of the Class of 2019 are no exception. A few soon-to-be fall graduates shared their thoughts about their journeys as they get ready to tackle new challenges after commencement.

Timothy Culbertson, 24, of Plano said he was drawn to UT Dallas specifically because of the healthcare studies program in the School of Interdisciplinary Studies. A transfer student and a U.S. Navy reservist, he found the courses offered at UTDallas both rigorous and a perfect fit for his interest in medicine.

My brother also came here [to UT Dallas], and I knew it was going to be challenging, Culbertson said. So I came prepared to study.

He found a second home on campus through the UTDallas Military and Veteran Center (MVC), where he worked as a Peer Advisor for Veteran Education (PAVE). His passion for serving in the military, he said, had a tremendous impact on his chosen career field medicine.

After graduation, Culbertson will begin his studies at The University of Texas Health Science Center at Houstons McGovern Medical School next fall. His primary goal is to serve veterans.

Culbertson will also soon celebrate another milestone before heading to medical school hes getting married in June.

What will you miss most about UTD?

The MVC. Ive made good friends, and probably my best times and best memories at UTDallas were hanging out there.

Would you rather have to retake a final exam or be Temoc for a day?

It depends on the final exam. If its one Im prepared for, I love the post-exam feeling. But if Im less prepared? Id rather be Temoc for a day.

What is a fun fact about you?

Ive never pulled an all-nighter while at UTD I always got at least four hours of sleep.

What are the best ways to survive a Monday?

Chick-fil-A Chick-n-Minis.

Whats the most Instagrammable spot on campus?

I dont have an Instagram, but if I did, it would be the main mall by the fountains.

Whats the first thing youll do to celebrate your graduation?

Im probably going to spend time with family and eat a nice, juicy steak.

What accomplishment/project are you most proud of from your time at UTD?

I would say mentoring both through PLTL (Peer-Led Team Learning) and PAVE. I had a lot of good mentoring when I first started here, and it was nice to pay it forward and give back to the UT Dallas community.

UT Dallas alumni make their mark wherever they go. How will you make yours?

After medical school, I really want to work with veterans, provide humanitarian aid overseas, serve my country and serve those who have served it as well.

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Media Contact: Katherine Morales, 972-883-4321,[emailprotected]or the Office of Media Relations, UT Dallas, (972) 883-2155, [emailprotected]

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Class of 2019: From Military to Medicine, Grad Discovers His Life's Duty - University of Texas at Dallas

signs Andrews Institute as official sports medicine provider – University of West Florida Newsroom – UWF Newsroom

Andrews Institute currently serves as the official medical partner, providing UWF athletics with team physicians. UWF and Andrews Institute signed a contract in which Andrews Institute will continue serving in this role and expand the partnership as the official sports medicine provider of UWF athletics for health care, orthopedic and sports medicine. Andrews Institute is the exclusive Official Medical Partner and Official Sports Medicine Provider of University Athletics Department for medical services including, but not limited to athletics, athletic training, physical therapy, orthopedic and sports medicine.

We are excited to expand our great relationship with the University of West Florida, said Dr. David Joyner, Andrews Institute executive director and senior vice president. What the University of West Florida stands for is truly astounding. We see this partnership as our world-class team taking care of another world-class team.

Andrews Institute will provide certified athletic trainers and athletic-training services for the 400 UWF student-athletes under the medical direction of team physicians Dr. Roger Ostrander and Dr. Joshua Hackel. Andrews Institute will also grant UWF athletes access to a full-time sports medicine physical therapist at Baptist Medical Park Nine Mile on University Parkway.

Two great organizations are joining to forge a transformative partnership that provides the highest quality care for our student-athletes, said Dave Scott, UWF athletics director. We are grateful for Andrews Institutes support and thrilled to have this world-class organization right in our own backyard.

UWF fields 15 athletic teams. The rich UWF athletics tradition includes nine national championshipsin five sports, 102 conference titles, 15 GSC womens all-sports trophies, eight GSC mens all-sports trophies and the GSC overall all-sports trophies every year since its inception in 2013-2014. The UWF football team will play Minnesota State at 2 p.m. on Saturday, Dec. 21, in McKinney, Texas, for the NCAA Division II national championship. This marks the second national title appearance for program in only its fourth year of existence.

Andrews Institute provides certified athletic trainers and team physicians to all 23 public high schools in a four county area, Chipola College, Pensacola Christian College and Pensacola Christian Academy.

For more information about the University of West Florida Department of Intercollegiate Athletics, visit http://www.goargos.com.

For more information about Andrews Institute for Orthopaedics & Sports Medicine, visit http://www.andrewsinstitute.com.

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signs Andrews Institute as official sports medicine provider - University of West Florida Newsroom - UWF Newsroom

School of Medicine Faculty Member Dr. Andrea Meyer Stinson to Serve as Partner on $200K Grant to Develop Trauma Informed Community in Middle Georgia -…

MACON Andrea S. Meyer Stinson, Ph.D., associate director of the Master of Family Therapy Program and associate professor of psychiatry and behavioral sciences/pediatrics in Mercer University School of Medicine, will serve as a partner and consultant on a two-year, $200,000 grant from the Pittulloch Foundation, in partnership with Resilient Georgia, to integrate trauma awareness into the Central Georgia community.

The Pittulloch Foundation and Resilient Georgia have offered grants to four cities and the surrounding counties to provide a regional emphasis on trauma informed awareness, Adverse Childhood Experiences (ACEs) and child sexual abuse prevention training as a basis to transform systems and procedures crossing both public and private sectors.

The Resilient Middle Georgia grant will be managed by the Community Partnership, a Bibb County collaborative that has been dedicated to making an impact in the lives of children and families for more than 20 years.

Dr. Meyer Stinson, who is a board member for Resilient Georgia, will serve as a partner on the Resilient Middle Georgia Project, alongside Jill Vanderhoek, executive director of Community Partnership in Bibb County, and the Community Foundation of Central Georgia. The project will focus on building awareness and a common language around trauma, adversity, ACEs and resilience in Bibb and other Middle Georgia counties.

Traumatic experiences often create long-lasting effects, and creating more opportunities in our area to inform providers of those effects will allow them to better serve the community, said Vanderhoek. We are grateful to the Pittulloch Foundation for providing this grant to help Middle Georgia and to Resilient Georgia and the Community Foundation for their support.

The primary aim of the grant is to bring together multiple stakeholders, including education, health care, social services, mental health providers, law enforcement, juvenile justice, families and community champions, to align conversations and build awareness and trainings that will better support children and families coping with adversity and trauma.

Adversity and challenges occur in all families, however some children and youth experience an accumulation of severe stressors that can impair their development and functioning, Dr. Meyer Stinson said. By bringing together our community to talk about and recognize trauma and ACEs as an important public health concern, we can move towards a common understanding and language about ways to help reduce the potential impact of these experiences.

Dr. Meyer Stinson will serve as a consultant for the grant and liaison between the School of Medicine and Resilient Middle Georgia. She will help in developing community-wide awareness events, coordinating renowned speakers, analyzing and reporting data, as well as planning education and training opportunities for School of Medicine students, faculty, staff and physician preceptors.

In order for individuals to thrive physically and mentally, it is essential to address both the family and the community in which they live, especially for rural and underserved areas, said Jean Sumner, M.D., dean of Mercer University School of Medicine. Dr. Meyer Stinsons involvement in this project will support our mission of working with rural and underserved individuals, while also building a network of well-trained and trauma informed healthcare providers for the broader region.

About Mercer University School of Medicine (Macon, Savannah and Columbus)

Mercer Universitys School of Medicine was established in 1982 to educate physicians and health professionals to meet the primary care and health care needs of rural and medically underserved areas of Georgia. Today, more than 60 percent of graduates currently practice in the state of Georgia, and of those, more than 80 percent are practicing in rural or medically underserved areas of Georgia. Mercer medical students benefit from a problem-based medical education program that provides early patient care experiences. Such an academic environment fosters the early development of clinical problem-solving and instills in each student an awareness of the place of the basic medical sciences in medical practice. The School opened a full four-year campus in Savannah in 2008 at Memorial University Medical Center. In 2012, the School began offering clinical education for third- and fourth-year medical students in Columbus. Following their second year, students participate in core clinical clerkships at the Schools primary teaching hospitals: Medical Center, Navicent Health in Macon; Memorial University Medical Center in Savannah; and The Medical Center and St. Francis Hospital in Columbus. The School also offers masters degrees in family therapy, preclinical sciences and biomedical sciences and a Ph.D. in rural health sciences.

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School of Medicine Faculty Member Dr. Andrea Meyer Stinson to Serve as Partner on $200K Grant to Develop Trauma Informed Community in Middle Georgia -...

Novartis embraces the digital world to reimagine medicine for patients – SiliconANGLE News

In a highly regulated space such as the pharmaceutical industry, the process of digital transformation has been slower than in other sectors. However, the Swiss pharmaceutical giant Novartis AG has been focused on changing this narrative in recent years as it embraced digital and data.

We are trying to reimagine medicine through user data and technology, said Loic Giraud (pictured, center), business analytics COE head at Novartis. Were trying to optimize the backbone of our day-to-day processes. Through the cloud we can make use of data to innovate, operate and engage.

Giraud spoke with Rebecca Knight (@knightrm), host of theCUBE, SiliconANGLE Medias mobile livestreaming studio, during the Accenture Executive Summit at the AWS re:Invent event in Las Vegas. He was joined by Fang Deng (pictured, right), big data and advanced analytics program lead at Novartis, and Vikas Sindwani (pictured, left), principal director of applied intelligence at Accenture. They discussed how Novartis is reimagining new products for patients using digital technologies and a growing industry acceptance of the cloud. (* Disclosure below.)

Novartis has developed a new platform Nerve Live which is designed to leverage the firms massive data pool. Faster and more thorough analysis of data, using artificial intelligence and machine learning, will help the company research and develop new drug therapies.

Were trying to reimagine our products for the patient, Deng said. Our objective is to leverage new technologies, concentrate on data in the cloud, and build a new platform for Novartis users.

The pharmaceutical company is also embracing the cloud. Earlier this month, Novartis announced that it would work with Amazon Web Services Inc. to overhaul its manufacturing and business operations.

Companies like healthcare, media, metals and mining were behind the curve in cloud-adoption rates because of their respective concerns around compliance and security of data, Sindwani explained. That trend is slowly shifting as companies are becoming more open. Theyve seen how the public cloud has matured.

Watch the complete video interview below, and be sure to check out more of SiliconANGLEs and theCUBEs coverage of the Accenture Executive Summit during the AWS re:Invent event. (* Disclosure: Accenture LLP sponsored this segment of theCUBE. Neither Accenture nor other sponsors have editorial control over content on theCUBE or SiliconANGLE.)

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New veterinary medicine research projects take on foot-and-mouth disease and ASF – Fence Post

MANHATTAN, Kan. High-priority diseases in cattle and swine will be tackled by three researchers in the Kansas State University College of Veterinary Medicine with grants totaling nearly $1 million from the U.S. Department of Agricultures Agricultural Research Service.

Jrgen Richt, Regents distinguished professor and director of the Center of Excellence for Emerging and Zoonotic Animal Diseases, received a $150,000 USDA ARS grant for Evaluation of Novel Foot-and-Mouth Disease Virus Vaccine Candidates with Broad Breadth of Protection Phase II.

With a $176,900 grant, Mike Sanderson, professor of epidemiology and associate director of the Center for Outcomes Research and Epidemiology, is leading the project Simulation Modeling of Foot-and-Mouth Disease Outbreaks in Livestock in the U.S.

Actions Supporting the Development of an African Swine Fever Virus Live Attenuated DIVA Vaccine is under the direction of Jishu Shi, professor of vaccine immunology, with a $640,720 grant.

Both Sandersons and Richts projects focus on foot-and-mouth disease, which affects livestock production in many regions of the world, including much of Asia and Africa.

Foot-and-mouth disease is a high-priority transboundary disease that would severely impair livestock health and production if introduced to the U.S., Sanderson said. The goal of this research is to model outbreak and control scenarios in the U.S. to improve preparedness and identify optimal disease response strategies to mitigate the impacts of a potential foot-and-mouth disease outbreak.

Because the foot-and-mouth disease virus is antigenically diverse, Richt said vaccines must be matched to target certain viral isolates to be effective.

The objective of this research project is to support the development of novel foot-and-mouth disease virus vaccine candidates and determine their immunogenicity in its natural host, Richt said. It will also help generate new knowledge on next-generation vaccines for this virus, with broader activity that will ultimately help to prevent and control foot-and-mouth disease.

Shis research is centered on the development of control strategies against African swine fever virus, a threatening swine disease that has become a major issue in China and other Asian countries.

The collaboration with USDA ARS is a valuable partnership for us in African swine fever vaccine research and highlights the importance of the K-State Biosecurity Research Institute as a key facility for K-State researchers working on high-consequence animal diseases, Shi said. It will strengthen our capability in research that will be related to the National Bio and Agro-defense Facility, or NBAF, and provide new impetus for our long-standing partnership with USDA ARS research scientists.

The Biosecurity Research Institute, known as BRI, is a biosafety-level 3 and biosafety-level 3 agriculture research facility that allows for the study of high-consequence pathogens affecting plants, animals and food products, including zoonotic pathogens that infect humans. NBAF will be the nations foremost animal disease research facility and is being built by the U.S. Department of Homeland Security adjacent to K-States Manhattan campus.

The two objectives of Shis project are the development of accompanying differentiation of infected from vaccinated animals, or DIVA, tests for the African swine fever virus live attenuated DIVA candidate developed by the ARS, and the development of a stable cell line supporting the replication of those vaccine candidates.

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New veterinary medicine research projects take on foot-and-mouth disease and ASF - Fence Post

Manchester bids to grow genomics and precision medicine hub with Citylabs 4.0 – EPM Magazine

Manchesters health innovation campus, Citylabs, is set for further expansion following high as it continues to grow its presence as an international hub for genomics and precision medicine.

Manchester Science Partnerships (MSP) and Manchester University NHS Foundation Trust (MFT) havesubmitted plans to develop Citylabs 4.0, a new 35 million development which will grow the existing Citylabs campus by 125,000 sq ft.

The Joint Venture partnership between MSP and MFT, the UK's largest NHS provider Trust, is the first of its kind, with the first phase - Citylabs 1.0 - already home to diagnostics, medtech, digital health and genomics businesses who are driving the future of medicine and healthcare.

Rowena Burns, chair, Manchester Science Partnerships, said: Weve seen huge developments and significant growth in the life sciences and digital technology sectors over the last five years, with pioneering solutions being created to tackle some of our most pressing health challenges. Were keen to harness the opportunities created by the growth in these sectors and our plans for Citylabs 4.0 speak to this ambition.

At Citylabs we have created a dynamic ecosystem, a place where companies and researchers work side by side, benefiting from being co-located on Europe's largest clinical academic campus."

Subject to planning approval by Manchester City Council, Citylabs 4.0 will be built at the south of the MFT Oxford Road campus, adjacent to Citylabs 2.0 & 3.0, and provide seven floors of office and lab space where brilliant research will be translated into new healthcare diagnostics and treatments which can then be quickly adopted into Manchesters health system.

Businesses at Citylabs have access to clinical and academic collaborators located on the campus, and a programme of business support including advice on funding sources, new markets, and professional services. Theyre also surrounded by hospitals and the UKs largest student population at the University of Manchester and Manchester Metropolitan University.

This campus extension follows the 60 million expansion underway to create Citylabs 2.0 and 3.0. Citylabs 2.0 is due for completion in late 2020 and will be home to diagnostics company Qiagen, who will base their European Hub for Diagnostics Development at the campus. Citylabs 3.0will begin construction following the completion of Citylabs 2.0.

Professor Neil Hanley, MFTs director of research and innovation, adde: We are all rightly proud that the Citylabs approach has brought together NHS, academic and commercial sectors, completely in line with the UK GovernmentsLife Sciences Industrial Strategywhich made this a national priority.

That we are now driving on with further buildings speaks volumes about our ambition for growth in research and innovation that benefits patient care and the regional economy. I look forward to plans for Citylabs 4.0 being realised.

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Manchester bids to grow genomics and precision medicine hub with Citylabs 4.0 - EPM Magazine

Sangamo Highlights Advancements in Genomic Medicine Pipeline and Expanded R&D and Manufacturing Capabilities at R&D Day – Business Wire

BRISBANE, Calif.--(BUSINESS WIRE)--Sangamo Therapeutics, Inc. (Nasdaq: SGMO), a genomic medicine company, is hosting an R&D Day today beginning at 8am Eastern Time. During the event, Sangamo executives and scientists plan to provide updates across the Companys clinical and preclinical pipeline, as well as an overview of manufacturing capabilities to support clinical and commercial supply. A live webcast link will be available on the Events and Presentations page of the Sangamo website

The talent, R&D capabilities, manufacturing expertise, and operations infrastructure we have brought to Sangamo have enabled us to advance a genomic medicine pipeline that spans multiple therapeutic areas and now also extends into late-stage development, said Sandy Macrae, CEO of Sangamo. As we make progress in clinical development, we gain insights into the use of our technology and are applying those insights as we advance new programs, such as the gene therapy for PKU and the genome regulation candidates for CNS diseases we are announcing today.

Macrae continued: We will continue to pursue a dual approach of retaining certain programs for our proprietary pipeline while also establishing pharmaceutical partnerships to gain access to therapeutic area expertise and financial, operational, and commercial resources. Strategic collaborations will be a particularly important consideration as we advance programs for diseases affecting large patient populations.

R&D Day updates on clinical and preclinical pipeline programs:

Gene therapy product candidates for hemophilia A, Fabry disease, and PKU

SB-525 is a gene therapy product candidate for hemophilia A being developed by Sangamo and Pfizer under a global development and commercialization collaboration agreement. The transfer of the SB-525 IND to Pfizer is substantially completed. Pfizer is advancing SB-525 into a Phase 3 registrational study in 2020 and has recently begun enrolling patients into a Phase 3 lead-in study.

At R&D Day, Sangamo executives are presenting data from the SB-525 program which were recently announced at the American Society of Hematology (ASH) annual meeting.

The cassette engineering, AAV engineering and manufacturing expertise which Sangamo used in the development of SB-525 are also being applied to the ST-920 Fabry disease program, which is being evaluated in a Phase 1/2 clinical trial, as well as to the newly announced ST-101 gene therapy program for PKU, which is being evaluated in preclinical studies with a planned IND submission in 2021.

Engineered ex vivo cell therapy candidates for beta thalassemia, kidney transplantation, and preclinical research in multiple sclerosis (MS)

Sangamo is providing an overview of the Companys diversified cell therapy pipeline this morning. Cell therapy incorporates Sangamos experience and core strengths, including cell culture and engineering, gene editing, and AAV manufacturing. At R&D Day, Sangamo scientists today are reviewing the early data presented this month at ASH from the ST-400 beta thalassemia ex vivo gene-edited cell therapy program, which is being developed in partnership with Sanofi.

Sangamo is also providing updates on the companys CAR-TREG clinical and preclinical programs. CAR-TREGS are regulatory T cells equipped with a chimeric antigen receptor. Sangamo is the pioneer in CAR-TREGS, which may have the potential to treat inflammatory and autoimmune diseases. TX200 is being evaluated in the STEADFAST study, the first ever clinical trial evaluating a CAR-TREG cell therapy. Tx200 is being developed for the prevention of immune-mediated organ rejection in patients who have received a kidney transplant, a significant unmet medical need. Results from this trial will provide data on safety and proof of mechanism, building a critical understanding of CAR-TREGS in patients, and may provide a gateway to autoimmune indications such as Crohns disease and multiple sclerosis (MS). Sangamo is also presenting preclinical murine data demonstrating that CAR-TREGS accumulate and proliferate in the CNS and reduce a marker of MS.

In vivo genome editing optimization

Clinical data presented earlier this year provided evidence that Sangamo had successfully edited the genome of patients with mucopolysaccharidosis type II (MPS II) but also suggested that the zinc finger nuclease in vivo gene editing reagents were under-dosed using first-generation technology. Sangamo has identified potential improvements that may enhance the potency of in vivo genome editing, including increasing total AAV vector dose, co-packaging both ZFNs in one AAV vector, and engineering second-generation AAVs, ZFNs, and donor transgenes.

Genome regulation pipeline candidates targeting neurodegenerative diseases including Alzheimers and Parkinsons

Sangamo scientists today are presenting data demonstrating that the companys engineered zinc finger protein transcription factors (ZFP-TFs) specifically and powerfully repress key genes involved in brain diseases including Alzheimers, Parkinsons, Huntingtons, ALS, and Prion diseases. Sangamo is advancing its first two genome regulation programs toward clinical development:

Sangamo scientists are also presenting data demonstrating progress in the development of new AAV serotypes for use in CNS diseases.

Manufacturing capabilities and strategy

Sangamo is nearing completion of its buildout of a GMP manufacturing facility at the new Company headquarters in Brisbane, CA. This facility is expected to become operational in 2020 and to provide clinical and commercial scale manufacturing capacity for cell and gene therapy programs. The Company has also initiated the buildout of a cell therapy manufacturing facility in Valbonne, France. Sangamos manufacturing strategy includes in-house capabilities as well as the use of contract manufacturing organizations, including a long-established relationship with Thermo Fisher Scientific for clinical and large-scale commercial AAV manufacturing capacity.

R&D Day webcast

A live webcast of the R&D Day, including audio and slides, will be available on the Events and Presentations page of the Sangamo website today at 8am Eastern Time. A replay of the event will be archived on the website.

About Sangamo Therapeutics

Sangamo Therapeutics is committed to translating ground-breaking science into genomic medicines with the potential to transform patients lives using gene therapy, ex vivo gene-edited cell therapy, and in vivo genome editing and gene regulation. For more information about Sangamo, visit http://www.sangamo.com.

Sangamo Forward Looking Statements

This press release contains forward-looking statements within the meaning of the "safe harbor" provisions of United States securities law. These forward-looking statements include, but are not limited to, the therapeutic potential of Sangamos product candidates; the design of clinical trials and expected timing for milestones, such as enrollment and presentation of data, the expected timing of release of additional data, plans to initiate additional studies for product candidates and timing and design of these studies; the expected benefits of Sangamos collaborations; the anticipated capabilities of Sangamos technologies; the research and development of novel gene-based therapies and the application of Sangamos ZFP technology platform to specific human diseases; successful manufacturing of Sangamos product candidates; the potential of Sangamos genome editing technology to safely treat genetic diseases; the potential for ZFNs to be effectively designed to treat diseases through genome editing; the potential for cell therapies to effectively treat diseases; and other statements that are not historical fact. These statements are based upon Sangamos current expectations and speak only as of the date hereof. Sangamos actual results may differ materially and adversely from those expressed in any forward-looking statements. Factors that could cause actual results to differ include, but are not limited to, risks and uncertainties related to dependence on the success of clinical trials; the uncertain regulatory approval process; the costly research and development process, including the uncertain timing of clinical trials; whether interim, preliminary or initial data from ongoing clinical trials will be representative of the final results from such clinical trials; whether the final results from ongoing clinical trials will validate and support the safety and efficacy of product candidates; the risk that clinical trial data are subject to differing interpretations by regulatory authorities; Sangamos limited experience in conducting later stage clinical trials and the potential inability of Sangamo and its partners to advance product candidates into registrational studies; Sangamos reliance on itself, partners and other third-parties to meet clinical and manufacturing obligations; Sangamos ability to maintain strategic partnerships; competing drugs and product candidates that may be superior to Sangamos product candidates; and the potential for technological developments by Sangamo's competitors that will obviate Sangamo's gene therapy technology. Actual results may differ from those projected in forward-looking statements due to risks and uncertainties that exist in Sangamos operations. This presentation concerns investigational drugs that are under preclinical and/or clinical investigation and which have not yet been approved for marketing by any regulatory agency. They are currently limited to investigational use, and no representations are made as to their safety or effectiveness for the purposes for which they are being investigated. Any discussions of safety or efficacy are only in reference to the specific results presented here and may not be indicative of an ultimate finding of safety or efficacy by regulatory agencies. These risks and uncertainties are described more fully in Sangamo's Annual Report on Form 10-K for the year ended December 31, 2018 as filed with the Securities and Exchange Commission on March 1, 2019 and Sangamo's Quarterly Report on Form 10-Q for the quarter ended September 30, 2019 that it filed on or about November 6, 2019. Except as required by law, we assume no obligation, and we disclaim any intent, to update these statements to reflect actual results.

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Sangamo Highlights Advancements in Genomic Medicine Pipeline and Expanded R&D and Manufacturing Capabilities at R&D Day - Business Wire

Water companies would be best advised to swallow their medicine – The Guardian

In a parallel political universe, Ofwats pricing framework for the English and Welsh water companies for the next five years would have been redundant before it was announced on Monday. Incoming Labour ministers would instead be inspecting their soon-to-be nationalised assets.

None of that will now happen, so the key issue in a still-privatised world is different. Will any of the companies that have bleated behind the scenes about a politicised regulatory process dare to allege unreasonable harshness on the part of Ofwat? Will any appeal to the Competition and Markets Authority (CMA)?

Well have to wait eight weeks the permitted period for an appeal to find out, but the likely suspects would be well advised to swallow their medicine.

First, Ofwats review is pitched as the toughest ever, but so it had to be. Shareholders since privatisation in 1989 have enjoyed a dividend bonanza so this was always going to be a moment to lean in the opposite direction. Thats not evidence of politicisation; its just a recognition that regulation has been too lax. Ofwats new demands will strike most bill-payers as reasonable: lower returns on capital; a reduction in bills by 50 on average, ignoring inflation, over the next five years; and a 16% cut in leaks.

Second, Ofwat has given some ground between its draft and final calculations. Companies, in aggregate, will be allowed about 1.5bn of extra expenditure to meet performance targets. The concession is not huge in the context of a 51bn spending programme, but its a softening.

Third, the new regime will only look tough to the laggards, judged by efficiency. Note how the share price of Severn Trent, one of three companies that got top-of-the-class fast track status during Ofwats review, is within pennies of its all-time high. Its shareholders see little to frighten them.

Fourth, an appeal to the CMA is not a one-way bet. The competition regulator is allowed to conclude that Ofwat should have been harder. That thought ought to concentrate minds in the boardrooms of the four companies Anglian, Northumbrian, Thames and Yorkshire that are thought most likely to appeal. Its time for them to accept that, in a privatised but regulated system, owners have to take a hit sometimes.

Its hard to keep up with transport firm FirstGroups view of its best strategy. Back in May, the future emphasis for the group was going to be First Student and First Transit, its two North American bus contractors, since they had the greatest potential to generate sustainable value and growth over time.

Now both operations may be sold. Whats prompted the U-turn? One can point to the arrival of David Martin as chairman in August but, since he seemed to endorse the May vision only last month, the latest development looks to be a lobbying triumph for activist investor Coast Capital, aided these days by fellow investor Robert Tchenguiz. The duo demanded a sale of all US assets, not just the Greyhound coaching business, a few weeks ago; now they may get it.

A UK-only future would be a mighty come-down for FirstGroup, which can currently call itself one of the worlds largest transport companies with 100,000 employees. Indeed, even within the UK, the future of the bus division is unclear, as FirstGroup is exploring what form of separation is possible while meeting pension obligations.

If the buses were also to exit along with the US assets, all that would be left would be the UK rail business, from which FirstGroup seemed to be contemplating an orderly retreat only a year ago. Then it won the West Coast Partnership franchise and all is now apparently right with rail.

One can view this strategic soul-searching as an exercise in rationalisation, the polite term for a break-up. Its hard, though, to escape the feeling that theres a simpler alternative to uncertain deal-making: just run the businesses better.

Mike Ashley has been banging on about his elevation strategy for years and now he has something to show for it: a share price that elevated by 31% in a day. Context is everything, however. The improvement to 472p merely took the shares back to where they stood at the start of 2016, which is roughly when Ashley adopted his other obsession diversification.

House of Fraser, the main product of that ambition, clearly isnt getting worse, which was why the shares jumped on Monday. But the eventual returns from the HoF deal remain a mystery. Ashley runs a tighter ship than the old management (no surprise there) but the long-term investment demands in the department store business are anyones guess.

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Water companies would be best advised to swallow their medicine - The Guardian

One in six GPs could quit medicine within a year, GMC report finds – GP online

The GMCs State of medical education and practice 2019 (SoMEP) report shows that 18% of GPs were considering leaving medicine entirely in 2020.

Nearly a quarter of GPs polled by the regulator 'gave responses that suggested they were at high risk of burnout' - and nearly one in 10 had taken a 'leave of absence due to stress' within the past 12 months. Around one in six GPs said they were unable to cope 'every day'.

GPs were significantly more likely to be dissatisfied than doctors as a whole - with 45% of GPs dissatisfied compared with 30% of all doctors.Increasing workload, long hours, difficulty dealing with patient expectation and bureaucracy were among key factors cited by GPs.

The report, which gathered responses from 1,079 GPs, found a growing shift towards part-time working in general practice; a trend theGMC said reflected deliberate choices by GPs to manage their wellbeing and protect against burnout.

A total of69% of full-time GPs said they were likely to reduce the amount of time they worked in clinical practice next year, and 36% of GPs had done so in 2019. Nearly half (45%) of GPs said they were already contracted to work less than full-time (LTFT).

The GMC highlighted an increasing number of doctors in GP training which grew by 6% in 2019, but warned it may not directly translate into reduced pressure on GP services because of the continuing trend towards LTFT working.

The regulator called for legislative change to allow a more streamlined process for registering overseas-trained doctors and innovative models of education to attract more doctors to general practice.

The GMC found that GPs working LTFT were more likely to be satisfied at work (6% higher) and less likely to be planning to leave the profession compared with full-time colleagues. Meanwhile, the analysis showed doctors who paused before starting their specialty training were, on average, at lower risk of burnout.

GMC chief executive Charlie Massey said: The challenge our health services are facing is no secret. We need more flexible training and career options if high levels of patient care and safety are to be sustained.

Doctors say they are no longer prepared to stick with the traditional career paths to meet that demand. We are seeing what looks like a permanent shift in the way newer doctors plan their careers.

That doctors are making choices for a better work-life balance and career development is a new reality which health services cannot ignore. Establishing a sustainable workforce and encouraging supply, particularly of expert generalists who can spread the burden in primary care, is vital.

RCGP chair Professor Martin Marshall said: It's not surprising to see more GPs reducing or planning to reduce the number of clinical hours they work. They shouldnt be criticised for this - its this flexibility in working patterns that general practice offers that makes the job sustainable, so that GPs and our teams can continue to deliver safe care to a million patients a day across the country.

Working "full-time" in general practice is simply not doable for many, and this is causing GPs to burn out, or leave the profession earlier than they planned to because they feel they cannot guarantee safe standards of care for their patients. It makes sense that GPs are making choices about their career to safeguard against this.'

BMA chair Dr Chaand Nagpaul said: 'Exhausted and burnt out doctors, overwhelmed by demand, are struggling to provide the level of care that patients deserve. This is affecting quality and safety of the care thats being delivered. Its clear that the impact of the state of the NHS is being felt across the whole profession from juniors beginning their careers, to experienced hospital doctors and GPs.

'The government and employers need to do more to retain the existing workforce. This means recognising the flexible working patterns that doctors are increasingly opting for, and as the BMA has consistently called for, a learning rather than a blame culture in the health service.'

GPonline reported last month that the full-time equivalent (FTE) fully-qualified GP workforce fell by 340 over the year to September 2019.

GP practices delivered a record 30.8m appointments in October 2019 - by far the highest figure recorded in a single month since NHS Digital began collecting data 18 months ago.

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One in six GPs could quit medicine within a year, GMC report finds - GP online

Medicine or Myth? The Dubious Benefits of Placenta-Eating – Undark Magazine

When Brooke Brumfield wasnt battling morning sickness, she craved nachos. Like many first-time expectant mothers, she was nervous and excited about her pregnancy. She had just bought a house with her husband, a wildland firefighter who had enrolled in paramedic school to transition to firefighting closer to home. Everything was going according to plan until 20 weeks into Brumfields pregnancy, when she lost her job at a financial technology startup and, with it, her salary and three months paid maternity leave. After building a new business to support her family, she had clients, but childcare was limited, and her husbands schedule was always shifting. By the time her baby arrived, everything was beyond overwhelming, Brumfield says. I pretty much felt like a truck hit me.

Brumfield had heard stories from friends and family about a way to minimize the stress and emotional fallout of the postpartum period: consuming her placenta, the vascular organ that nourishes and protects the fetus during pregnancy and is expelled from the body after birth. The women swore by the results. They said their milk supply improved and their energy spiked. The lows caused by plummeting hormone levels didnt feel as crushing, they explained.

Brumfield enlisted her doula who, for a fee, would steam, dehydrate, and pulverize her placenta, pouring the fine powder into small capsules. She swallowed her placenta pills for about six weeks after delivering her daughter. She said they helped her feel more even, less angry and emotional. When her milk supply dipped, she says, I re-upped my intake and [the problem] was solved.

Social scientists and medical researchers call the practice of consuming ones own placenta placentophagy. Once confined to obscure corners of alternative medicine and the countercultures crunchier communities, it has been picked up by celebrities (Kourtney and Kim Kardashian, January Jones, Mayim Bialik, Alicia Silverstone, Chrissy Teigen) and adopted by the wider public.

Although there are no official estimates of how many women ingest their placenta after delivery, the internet is increasingly crowded with placenta service providers preparers of pills, smoothies, and salves to support new mothers in the slog to recovery. But the purported benefits are disputed. Depending on whom you ask, placenta-eating is either medicine or a potentially dangerous practice based on myth. How did this practice go mainstream, despite a lack of reported scientific or clinical benefits? The answer may say much more about the world new mothers live in than it does about the placenta.

In any doctors office or primary care setting, a provider treating a patient will often mention new research that supports a recommended treatment. A pregnant woman diagnosed with preeclampsia, for example, might learn from her health care provider that low-dose aspirin has been shown in recent studies to reduce serious maternal or fetal complications. But the basis for placentophagy, a practice that lies beyond the boundaries of biomedicine, is a 16th-century text.

Li Shizhens Compendium of Materia Medica, or Bencao gangmu, first published in 1596, is a Chinese pharmacopoeia and the most celebrated book in the Chinese tradition of pharmacognosy, or the study of medicinal plants. It appears on the websites of placenta service providers and in the pages of the standard references for practitioners of traditional Chinese medicine (TCM), a millennia-old medical system with a growing global reach.

The basis for placentophagy, a practice that lies beyond the boundaries of biomedicine, is a 16th-century text.

A physician and herbalist, Li drew on his empirical experiences treating patients but also on anecdotes, poetry, and oral histories. His encyclopedia of the natural world is a textual cabinet of natural curiosities, according to historian Carla Nappis The Monkey and the Inkpot, a study of Lis life and work. Containing nearly 1,900 substances, from ginseng and peppercorn to dragons bone and turtle sperm, Lis book describes dried human placenta as a drug that invigorated people, and was used to treat impotence and infertility, among other conditions. For advocates of placentophagy, this book serves as ethnomedical proof of the long-standing history of the practice and by extension, its efficacy and safety.

But like many claims to age-old provenance, the origins of placentophagy as a postpartum treatment are disputed. Sabine Wilms, an author and translator of more than a dozen books on Chinese medicine, scrutinized classical Chinese texts on gynecology and childbirth and told me theres no written evidence at all of a woman consuming her own placenta after birth as a mainstream traditional practice in China, even if formulas containing dried human placenta were prescribed for other conditions, as described in Lis book.

Beyond Lis 400-year-old encyclopedia, evidence of postpartum placenta-eating is nearly impossible to find in the historical record. Womens voices are notoriously difficult to unearth from the archives, and even in the 19th century, the details of childbirth and what happened to the placenta went largely unreported. But when two University of Nevada, Las Vegas anthropologists pored over ethnographic data from 179 societies, they discovered a conspicuous absence of cultural traditions associated with maternal placentophagy.

The earliest modern recorded evidence of placentophagy appears in a June 1972 issue of Rolling Stone. I pushed the placenta into a pot, wrote an anonymous author, responding to the magazines call asking readers to share stories from their personal lives. It was magnificent purple and red and turquoise. Describing her steamed placenta as wonderfully replenishing and delicious, she recounted eating and sharing it with friends after delivering her son.

Evidence of postpartum placenta-eating is nearly impossible to find in the historical record.

Raven Lang, who is credited with reviving the oldest known and most commonly used recipe for postpartum placenta preparation, witnessed placentophagy while helping women as a homebirth midwife and TCM practitioner in California in the early 1970s. These women lived off the land, she explained, and might have drawn inspiration from livestock and other animals in their midst.

It wasnt long before placentophagy made its way beyond Californias hippie enclaves. In 1984, Mary Field, a certified midwife and registered nurse in the U.K., recounted eating her placenta, an unmentionable experience, to ward off postpartum depression after the birth of her second child. I remain secretive, Field wrote, for the practice verges on that other taboo cannibalism as it is human flesh and a part of your own body. She recalled choking down her own placenta. I could not bear to chew or taste it.

The rise of encapsulation technology, developed for the food industry and picked up by placenta service providers in the early aughts, put an end to visceral experiences like Fields. No longer must women process their own placenta or subject themselves to its purported offal-like flavor. Tidy, pre-portioned placenta pills resembling vitamins can be prepared by anyone with access to a dehydrator, basic supplies, and online training videos.

The boom in placentophagy highlights a longstanding puzzle for researchers. Almost every non-human mammal consumes its placenta after delivery, for reasons that remain unclear to scientists. Why did humans become the exception to this nearly universal mammalian rule? For Daniel Benyshek, an anthropologist and co-author of the UNLV study that found no evidence of placentophagy being practiced anywhere in the world, the human exception raises a red flag: It suggests the reasons that humans have eschewed placentophagy arent just cultural or symbolic, but adaptive that theres something dangerous about it, or at least there has been in our evolutionary history.

Scientific data on the potential benefits and risks of placentophagy is scarce, but a few small studies suggest that any nutrients contained in cooked or encapsulated placental tissue are unlikely to be absorbed into the bloodstream at concentrations large enough to produce significant health effects. Whether and in what quantity reproductive hormones such as estrogen survive placental processing has been little studied, but ingesting them after birth could have negative effects on milk production and may also increase the risk of blood clots.

Almost every non-human mammal consumes its placenta after delivery, for reasons that remain unclear to scientists.

Yet placental encapsulation services which remain unregulated in the U.S. have found a receptive audience of American consumers. (The food safety agency of the European Union declared the placenta a novel food in 2015, effectively shuttering the encapsulation business on the continent.) Mostly small and women-owned, placenta service businesses position themselves as an alternative to a highly medicalized, bureaucratized birthing process that has often neglected the needs of women. Postpartum checkups focus narrowly on pelvic examinations and contraceptive education. One survey of U.S. mothers found that one in three respondents who received a postpartum checkup felt that their health concerns were not addressed. In contrast, placenta service providers speak the language of empowerment.

That language can resonate with new mothers like Brumfield, who face overwhelming pressures to care for a newborn, nurse on demand, manage a household, and return to work amid anxieties about postpartum depression, dwindling energy, and inadequate milk supply.

In some ways, placenta consumption is motivated by a desire to perform good mothering, wrote scholars from Denmark and the United States in a paper on the emergence of the placenta economy. It reflects the idea of maternity as a neoliberal project, in which new mothers are responsible for their own individual well-being as well as that of their babies, they added.

Meanwhile, rates of postpartum depression keep climbing, maternity leave policies are stingy, and child care costs are often prohibitive. Its easy to see why many women would be eager to seek help, real or perceived, wherever they can find it.

Daniela Blei is a historian, writer, and book editor based in San Francisco.

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Medicine or Myth? The Dubious Benefits of Placenta-Eating - Undark Magazine

National Science Foundation Awards Grant to Develop Next-Generation Cloud Computing Testbed Powered by Red Hat – Yahoo Finance

Grant to fund creation of national cloud testbed aimed at accelerating innovation in advanced infrastructure technologies

Red Hat, Inc., the world's leading provider of open source solutions, today announced that the National Science Foundation (NSF) Division of Computer and Network Systems has awarded a grant to a research team from Boston University, Northeastern University and the University of Massachusetts Amherst (UMass) to help fund the development of a national cloud testbed for research and development of new cloud computing platforms.

The testbed, known as the Open Cloud Testbed, will integrate capabilities previously developed for the CloudLab testbed into the Massachusetts Open Cloud (MOC), a production cloud developed collaboratively by academia, government, and industry through a partnership anchored at Boston Universitys Hariri Institute for Computing. As a founding industry partner and long-time collaborator on the MOC project, Red Hat will work with Northeastern University and UMass, as well as other government and industry collaborators, to build the national testbed on Red Hats open hybrid cloud technologies.

Testbeds such as the one being constructed by the research team, are critical for enabling new cloud technologies and making the services they provide more efficient and accessible to a wider range of scientists focusing on research in computer systems and other sciences.

By combining open source technologies and a production cloud enhanced with programmable hardware through field-programmable gate arrays (FPGAs), the project aims to close a gap in computing capabilities currently available to researchers. As a result, the testbed is expected to help accelerate innovation by enabling greater scale and increased collaboration between research teams and open source communities. Red Hat researchers plan to contribute to active research in the testbed, including a wide range of projects on FPGA hardware tools, middleware, operating systems and security.

Beyond this, the project also aims to identify, attract, educate and retain the next generation of researchers in this field and accelerate technology transfer from academic research to practical use via collaboration with industry partners such as Red Hat.

Since its launch in 2014, Red Hat has served as a core partner of the MOC, which brings together talent and technologies from various academic, government, non-profit, and industry organizations to collaboratively create an open, production-grade public cloud suitable for cutting-edge research and development. The MOCs open cloud stack is based on Red Hat Enterprise Linux, Red Hat OpenStack Platform and Red Hat OpenShift.

Beyond creating the national testbed, the grant will also extend Red Hats collaboration with Boston University researchers to develop self-service capabilities for the MOCs cloud resources. For example, via contributions to the OpenStack bare metal provisioning program (Ironic), the collaboration aims to produce production quality Elastic Secure Infrastructure (ESI) software, a key piece to enabling more flexible and secure resource sharing between different datacenter clusters. And by sharing new developments that enable moving resources between bare metal machines and Red Hat OpenStack or Kubernetes clusters in open source communities such as Ironic or Ansible, Red Hat and the MOCs researchers are helping to advance technology well beyond the Open Cloud Testbed.

Supporting Quotes

Michael Zink, associate professor, Electrical and Computer Engineering (ECE), University of Massachusetts Amherst"This testbed will help accelerate innovation in cloud technologies, technologies affecting almost all of computing today. By providing capabilities that currently are only available to researchers within a few large commercial cloud providers, the new testbed will allow diverse communities to exploit these technologies, thus democratizing cloud-computing research and allowing increased collaboration between the research and open-source communities. We look forward to continuing the collaboration in MOC to see what we can accomplish with the testbed."

Orran Krieger, professor of Electrical and Computer Engineering, Boston University; co-director, Red Hat Collaboratory; PI, Massachusetts Open Cloud"An important part of the MOC has always been to enable cloud computing research by the academic community. This project dramatically expands our ability to support researchers both by providing much richer capabilities and by expanding from a regional to a national community of researchers."

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Chris Wright, senior vice president and chief technology officer, Red Hat"This grant and the work being done by the MOC show how open source solutions can positively impact real-world challenges outside of enterprise data centers. Red Hat is no stranger to pioneering new ways in which open source software can be used for innovative research, and we are pleased to help drive this initiative in bringing open cloud technologies to a wider range of disciplines, from social sciences to physics, while also continuing our commitment to the next generation of open source practitioners."

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About Red Hat, Inc.

Red Hat is the worlds leading provider of enterprise open source software solutions, using a community-powered approach to deliver reliable and high-performing Linux, hybrid cloud, container, and Kubernetes technologies. Red Hat helps customers integrate new and existing IT applications, develop cloud-native applications, standardize on our industry-leading operating system, and automate, secure, and manage complex environments. Award-winning support, training, and consulting services make Red Hat a trusted adviser to the Fortune 500. As a strategic partner to cloud providers, system integrators, application vendors, customers, and open source communities, Red Hat can help organizations prepare for the digital future.

Forward-Looking Statements

Certain statements contained in this press release may constitute "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements provide current expectations of future events based on certain assumptions and include any statement that does not directly relate to any historical or current fact. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including: risks related to the ability of the Company to compete effectively; the ability to deliver and stimulate demand for new products and technological innovations on a timely basis; delays or reductions in information technology spending; the integration of acquisitions and the ability to market successfully acquired technologies and products; risks related to errors or defects in our offerings and third-party products upon which our offerings depend; risks related to the security of our offerings and other data security vulnerabilities; fluctuations in exchange rates; changes in and a dependence on key personnel; the effects of industry consolidation; uncertainty and adverse results in litigation and related settlements; the inability to adequately protect Company intellectual property and the potential for infringement or breach of license claims of or relating to third party intellectual property; the ability to meet financial and operational challenges encountered in our international operations; and ineffective management of, and control over, the Company's growth and international operations, as well as other factors. In addition to these factors, actual future performance, outcomes, and results may differ materially because of more general factors including (without limitation) general industry and market conditions and growth rates, economic and political conditions, governmental and public policy changes and the impact of natural disasters such as earthquakes and floods. The forward-looking statements included in this press release represent the Company's views as of the date of this press release and these views could change. However, while the Company may elect to update these forward-looking statements at some point in the future, the Company specifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing the Company's views as of any date subsequent to the date of this press release.

Red Hat, Red Hat Enterprise Linux, the Red Hat logo, and OpenShift are trademarks or registered trademarks of Red Hat, Inc. or its subsidiaries in the U.S. and other countries. Linux is the registered trademark of Linus Torvalds in the U.S. and other countries. The OpenStack Word Mark is either a registered trademark/service mark or trademark/service mark of the OpenStack Foundation, in the United States and other countries, and is used with the OpenStack Foundation's permission. Red Hat is not affiliated with, endorsed or sponsored by the OpenStack Foundation, or the OpenStack community.

View source version on businesswire.com: https://www.businesswire.com/news/home/20191218005067/en/

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Media Contact:Gaby Berkman Red Hat, Inc. +1 978-392-2495 gberkman@redhat.com

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National Science Foundation Awards Grant to Develop Next-Generation Cloud Computing Testbed Powered by Red Hat - Yahoo Finance

The rise of cloud computing is having an impact on data center efficiency and it’s not great – Utility Dive

Dive Brief:

Uptime Institute's 2019 survey found data centers averaged a PUE of 1.67, versus a PUE of 1.8 in 2011, meaning more of the energy that data centers consume is used for computing processes. That's a significant improvement, but the industry may be losing ground.

The rise of cloud computing is putting downward pressure on data center PUEas fewer computers are now doing the actual work, according to the Uptime Institute, an advisory group focused on business infrastructure. This follows years of improvement.

"Improvements in data center facility energy efficiency have flattened out and even deteriorated slightly in the past two years," according to the firm's annual survey, conducted online in March and April with 1,600 respondents.

Larger and more efficient data centers that power the cloud are doing more of the work now, with efficiency improvements slowing at smaller centers as the computing migrates.

"It's not overall efficiency that is stalled out it's infrastructure efficiency," Matt Stansberry, the institute's vice president for North American operations, told Utility Dive. "For a long time, data centers were highly inefficient so, for every unit of energy used to run IT equipment doing productive work, there was a giant amount of overhead."

The PUE ratio "went down over the last 10 years as people started paying attention and making improvements," Stansberry said. Primarily, those improvements were to cooling systems. But with the rise of cloud computing, companies are using fewer computers and instead are relying on cloud-based systems.

"But [data center]buildings don't shift in real-time" to adjust the infrastructure supporting those computers, Stansberry said.

As more computing is done via the cloud, fewer computers mean these data centers may be over-built and less efficient. For utilities, they likely wont see significant load changes in the near term, though older data centers could close and growth in new additions could slow.

Further improvements to data center efficiency "will require significant investment and effort, with increasingly diminishing returns," Uptime Institute concluded. "While managers and operators should remain vigilant and seek to maintain high facility efficiency levels, higher gains may be found by focusing on IT efficiency."

That doesn't mean there isn't room for more traditional efficiency, Jim Kozlowski, vice president of global capacity planning and data center operations at Ensono, an IT services provider.

"Utilities help drive data center efficiency," Kozlowski told Utility Dive in an email. "By driving incentives or better economics, data center users will install more energy efficient infrastructure in the long term."

Many companies are in the process of modernizing their data centers, Kozlowski said. "So as they upgrade equipment and building management systems to meet certain standards, energy efficiency is improving."

The federal government has been keeping an eye on the sector as well. In 2016, the U.S. Department of Energy's Advanced Research Projects Agency-Energy offered $25 million for projects and technologies focused on increasing the energy efficiency of data centers.

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The rise of cloud computing is having an impact on data center efficiency and it's not great - Utility Dive

Cloud computing in 2020: views of the industry – Techerati

We asked six industry experts to weigh in on whats now and whats next in cloud computing

When we published our selection of cloud predictions last year, most predicted container orchestrator Kubernetes to consolidate its stranglehold over the container space and, correspondingly, modern cloud infrastructure.

Last November, one of the most extensive customer surveys bore this prediction out. In its study of thousands of companies, cloud and infrastructure monitoring company Datadog found 45 percent of its customers were using Kubernetes. And if that isnt evidence enough, just reflect on VMwares announcement in March that it plans to transition its enterprise virtualisation platform to a system that runs (and runs on) Kubernetes.

But in reality, Kubernetes centrality to cloud was put beyond doubt weeks before we published last years roundup. In January, IBM steamrollered into 2019 fresh off the back of its $34 billion acquisition of Red Hat. This year IBM confirmed it would integrate Red Hats popular Kubernetes implementation, OpenShift, into a new multi-cloud business focus.

It is in this context that most of this years experts consulted their cloud crystal balls. Rackspaces Lee James predicts 2020 to be a year of stiff competition between enterprise IT giants jostling to deliver a Kubernetes solution that unlocks multi-cloud for their customers. On the other hand, Stephan Fabel of Canonical says end-users will start to understand the limitations of Kubernetes, and accordingly, utilise it more strategically. Lastly, Pivotals Michael Cote expects companies to use this new-found savoir-faire to establish a singular, overall Kubernetes strategy.

Read the predictions in their entirety below.

Hybrid becomes the new multi-cloud, again

While the popularity of multi-cloud is undisputed with 81 per cent of companies using cloud technologies in some way, many firms are still making investments in their private cloud solutions. This is due to a number of reasons, such as the security posture, ongoing data centre leasing, or just because its the best platform for the application in some cases business. Indeed, even the UK Government plans to revise its cloud first policy to cloud right (or something similar) early next year, acknowledging that public cloud isnt right for everyone or every use case.

Reflecting this trend, weve seen the cloud giants respond with private cloud solutions that link directly into their public cloud solutions, such as Azure Arc, Google Cloud Anthos and AWS Outposts.

In 2020, theres going to be significant competition between the three biggest cloud hyperscalers and VMware as they all explore and deliver on how Kubernetes will unlock their potential to be the multi hybrid cloud provider of choice for customers. For customers, its ultimately going to come down to which fits and works best, as well as what gives the best bang for their buck. But this sets us up for an exciting year of new product and service announcements as each of the major cloud companies try to establish themselves as the cloud broker of choice.

Unicorn start-ups will begin repatriating workloads from the cloud

There has been a lot said about cloud repatriation of late. While this wont be a mass exodus from the cloud in fact quite the opposite, with public cloud growth expected to increase 2020 will see cloud native organisations leveraging a hybrid environment to enjoy greater cost savings.

For businesses starting out or working with limited budgets, which require an environment for playing around with the latest technology, public cloud is the perfect place to start. With the public cloud, you are your own limit and get immediate reward for innovation. But as these costs begin mounting, its prudent to consider how to regain control of cloud economics.

Repatriating workloads to on-premise is certainly a viable option, but it doesnt mean to say that we will start to see the decline of cloud. As organisations get past each new milestone in the development process, repatriation becomes more and more of a challenge. What we will likely see is public cloud providers reaching into the data centre to support this hybrid demand, so that they can capitalise on the trend

Kubernetes has become an integral part of modern cloud infrastructure and serves as a gateway to building and experimenting with new technology. Its little surprise that many companies we observe are doubling down on the application and reorienting their DevOps team around it to explore new things such as enabling serverless applications and automating data orchestration. We think this trend will continue at strength in 2020.

On a more cautious note, we may also see some companies questioning whether Kubernetes is really the correct tool for their purposes. While the technology can provide tremendous value, in some cases it can be complex to manage and requires specialist skills.

As Kubernetes is now commonly being used for production at scale, it becomes increasingly likely that users encounter issues around security and downtime. As a result of these challenges, we can expect the community will mature and in some cases come to the viewpoint that it might not be right for every application or increase the need to bring in outsourced vendors to aid with specialised expertise.

Organisations should try to find one standard Kubernetes approach

Kubernetes has already emerged as the leading choice for running containerised or cloud native applications. Organisations will now spend the time to create a kubernetes strategy, choosing the distro or services theyll use, to then run a few applications on it. Having multiple initiatives here would be a huge waste and delay the overall strategy. Instead organisations should try to find one standard Kubernetes approach. In 2020, though, the bulk of the work will be finding and modernising the apps that will run on that platform.

Most large organisations are doing just that and will spend 2020 modernising how they build and run software. To start, they need to find a handful of small, high value applications and the services those applications use. Then, run a working Proof of Concept (POC) to validate the platform choice by launching actual applications on the platform.

If it goes well, organisations can then put more apps on it. If it doesnt go well, they can try to find out why and try again, maybe with a new platform. Its important to look at the full end-to-end process: from development, to running in production, to re-deploying companies need to judge the success of the platform choice.

All applications will become mission-critical

The number of applications that businesses classify as mission-critical will rise during 2020 paving the way to a landscape in which every app is considered a high-priority. Previously, organizations have been prepared to distinguish between mission-critical apps and non-mission-critical apps. As businesses become completely reliant on their digital infrastructure, the ability to make this distinction becomes very difficult.

On average, the 2019 Veeam Cloud Data Management report revealed that IT decision-makers say their business can tolerate a maximum of two hours downtime of mission-critical apps. But what apps can any enterprise realistically afford to have unavailable for this amount of time? Application downtime costs organisations a total of $20.1 million globally in lost revenue and productivity each year, with lost data from mission-critical apps costing an average of $102,450 per hour. The truth is that every app is critical.

Businesses will continue to pick and choose the storage technologies and hardware that work best for their organisation, but data centre management will become even more about software. Manual provisioning of IT infrastructure is fast-becoming a thing of the past. Infrastructure as Code (IaC) will continue its proliferation into mainstream consciousness. Allowing business to create a blueprint of what infrastructure should do, then deploy it across all storage environments and locations, IaC reduces the time and cost of provisioning infrastructure across multiple sites.

Software-defined approaches such as IaC and Cloud-Native a strategy which natively utilises services and infrastructure from cloud computing providers are not all about cost though. Automating replication procedures and leveraging the public cloud offers precision, agility and scalability enabling organisations to deploy applications with speed and ease. With over three-quarters of organisations using software-as-a-service (SaaS), a software-defined approach to data management is now relevant to the vast majority of businesses.

Companies will take a step down from the cloud

The pattern goes something like this: lift and shift infrastructure VMs to the cloud, see costs actually go up, then move some workloads back to on-prem, then application lifecycle drivers push new apps (or new features for old apps) to be built in the cloud using PaaS/DbaaS technologies with more favourable cost model, then retire old IaaS apps. The key takeaway is this dynamic is one of the drivers for hybrid approaches.

We saw many companies this past year lift and shift to the cloud. Now, in 2020, I expect well see companies take a step back, and reevaluate their all-in approach. After feeling the effects of the full shift to cloud, the high associated costs and lack of flexibility, many companies will likely move to a multi-cloud or hybrid cloud approach next year.

Taking a hybrid cloud approach enables organizations to leverage the cloud (using AWS, Azure, or GCP) for some applications and computing needs while still keeping mission-critical or sensitive data closer to home. With a multi-cloud strategy, organizations can reduce costs and, instead of being constrained to one cloud, departments have the flexibility to select the service that works best for their individual needs (using a mix of AWS, Azure, or GCP).

Customers and organisations will really begin to look for more management layers on top of their solutions

One of the things I believe well see in 2020 is the true adoption of things like hybrid and multi-cloud solutions but the difference in this upcoming year will be that customers and organisations will really begin to look for more management layers on top of their solutions.

A lot of companies already have things like backup-in-the-cloud and DRaaS somewhere else, so what theyre now looking for is a uniform management layer on top of that to give visibility on cost, as well as a knowledge of where all data is located. Its important to know where data lives, whether workloads are protected, and whether they need to move workloads between different clouds if and when requirements change.

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Cloud computing in 2020: views of the industry - Techerati

Cloud Computing Security: Agencies Increased Their Use of the Federal Authorization Program, but Improved Oversight and Implementation Are Needed -…

What GAO Found

The 24 federal agencies GAO surveyed reported using the Federal Risk and Authorization Management Program (FedRAMP) for authorizing cloud services. From June 2017 to July 2019, the number of authorizations granted through FedRAMP by the 24 agencies increased from 390 to 926, a 137 percent increase. However, 15 agencies reported that they did not always use the program for authorizing cloud services. For example, one agency reported that it used 90 cloud services that were not authorized through FedRAMP and the other 14 agencies reported using a total of 157 cloud services that were not authorized through the program. In addition, 31 of 47 cloud service providers reported that during fiscal year 2017, agencies used providers' cloud services that had not been authorized through FedRAMP. Although the Office of Management and Budget (OMB) required agencies to use the program, it did not effectively monitor agencies' compliance with this requirement. Consequently, OMB may have less assurance that cloud services used by agencies meet federal security requirements.

Four selected agencies did not consistently address key elements of the FedRAMP authorization process (see table). Officials at the agencies attributed some of these shortcomings to a lack of clarity in the FedRAMP guidance.

Agency Implementation of Key Elements of the FedRAMP Authorization Process

HHS

GSA

EPA

USAID

Element

Control implementation summaries identified security control responsibilities

Security plans addressed required information on control implementation

Security assessment reports summarized results of control tests

Remedial action plans addressed required information

Cloud service authorizations prepared and provided to FedRAMP Program Office

Legend: fully addressed the element partially addressed the element

FedRAMP = Federal Risk and Authorization Management Program; HHS = Department of Health and Human Services; GSA = General Services Administration; EPA = Environmental Protection Agency; USAID = U.S. Agency for International Development

Source: GAO analysis of agency documentation| GAO-20-126

Program participants identified several benefits, but also noted challenges with implementing the FedRAMP. For example, almost half of the 24 agencies reported that the program had improved the security of their data. However, participants reported ongoing challenges with resources needed to comply with the program. GSA took steps to improve the program, but its FedRAMP guidance on requirements and responsibilities was not always clear and the program's process for monitoring the status of security controls over cloud services was limited. Until GSA addresses these challenges, agency implementation of the program's requirements will likely remain inconsistent.

Federal agencies use internet-based (cloud) services to fulfill their missions. GSA manages FedRAMP, which provides a standardized approach to ensure that cloud services meet federal security requirements. OMB requires agencies to use FedRAMP to authorize the use of cloud services.

GAO was asked to review FedRAMP. The objectives were to determine the extent to which 1) federal agencies used FedRAMP to authorize cloud services, 2) selected agencies addressed key elements of the program's authorization process, and 3) program participants identified FedRAMP benefits and challenges. GAO analyzed survey responses from 24 federal agencies and 47 cloud service providers. GAO also reviewed policies, plans, procedures, and authorization packages for cloud services at four selected federal agencies and interviewed officials from federal agencies, the FedRAMP program office, and OMB.

GAO is making one recommendation to OMB to enhance oversight, two to GSA to improve guidance and monitoring, and 22 to the selected agencies, including GSA. GSA and HHS agreed with the recommendations, USAID generally agreed, EPA generally disagreed, and OMB neither agreed nor disagreed. GAO revised four recommendations and withdrew one based on new information provided; it maintains that the remaining recommendations are warranted.

For more information, contact Gregory C. Wilshusen at (202) 512-6244 or wilshuseng@gao.gov.

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Cloud Computing Security: Agencies Increased Their Use of the Federal Authorization Program, but Improved Oversight and Implementation Are Needed -...

The Top 13 Cloud Computing Conferences to Attend in 2020 – Solutions Review

What are the top cloud computing conferences to visit in 2020? Tech conferences are some of the best places to learn about whats happening in a specific technology field. Not only are you able to hear the top tech experts speak, but you can network with professionals with an abundance of combined technical and operational knowledge.

As 2020 is almost upon us, were looking to the future to list 13 cant-miss conferences centered around cloud computing. These conferences cover every corner of the globe and span the entire year. Weve also included links to each conferences website so you can find more information or book your ticket!

WHEN: NumerousdatesWHERE:Numerous locations

Microsoft Ignite The Tour brings the very best of Microsoft Ignite to a city near you. The tour provides technical training led by Microsoft experts and your community. Youll learn new ways to build solutions, migrate and manage infrastructure, and connect with local industry leaders and peers.

You can find out more info here.

WHEN:Numerous datesWHERE: Numerous locations

Corporate infrastructure will enter a whole new dimension towards 2030. Existing ways of thinking will no longer suffice, and a people-centric New World will fundamentally change the business itself. In Gartner IT Infrastructure, Operations & Cloud Strategies Conference 2020, we will present strategies to be adopted, actions to be taken, and advices on how to achieve it for future-oriented business and technology leaders based on future trends.

You can find out more info here.

WHEN:March 11th 12thWHERE:London, UK

Technology enabled change is on the boardroom agenda for businesses of all types and sizes. Cloud Expo Europe is the UKs leading event for connecting technologists, business leaders and senior business managers with experts, solutions and services to help accelerate digital transformation plans. Whether you are cloud-first, scaling up, refining, or just getting started, Cloud Expo Europe is an unrivaled opportunity to meet with leading technology innovators and service providers. Network with your peers. Access a wealth of knowledge and advice including emerging trends, tech deep dives, lessons learned and market forecasts.

You can find out more info here.

WHEN:March 14th 19thWHERE:Europa-Park, Germany

CloudFest 2020 is the second in a three-year theme arc. We began with hyperscale enablement: go big or go home! Now we will explore how AI helps you maximize the potential that hypervisor partnership offers. The Intelligent Cloud allows AI to manage and distribute complex workloads, with smart tools that make interoperability and scale more cost-effective and efficient. Its a tech paradigm that is coming up quickly, and CloudFest will help pave the way so you can be in the drivers seat. CloudFest will explore how the cloud industry is preparing for the AI evolution in terms of technology, oversight, economics, and morality.

You can find out more info here.

WHEN:March 30th April 2ndWHERE:Zuidas, Amsterdam, The Netherlands

The Cloud Native Computing Foundations flagship conference gathers adopters and technologists from leading open source and cloud native communities in Amsterdam, The Netherlands from March 30 April 2, 2020. Join Kubernetes, Prometheus, Envoy, CoreDNS, containerd, Fluentd, Jaeger, Vitess, OpenTracing, gRPC, CNI, Notary, TUF, NATS, Linkerd, Helm, Rook, Harbor, etcd, Open Policy Agent, CRI-O, TiKV, and CloudEvents as the community gathers for four days to further the education and advancement of cloud native computing.

You can find out more info here.

WHEN:April 6th 8thWHERE:San Francisco, California

Were bringing together some of the brightest minds in tech for 3 days of networking, learning, and collaboration. Experience the magic of Google Cloud Next alongside IT professionals, developers, executives, and Google experts.

You can find out more info here.

WHEN:May 12th 14thWHERE:Miami Beach, Florida

2020 is bringing you a Cloud Summit unlike any youve ever experiencedwith more of everything you need to succeed. With 50+ cutting-edge breakout sessions. world-class keynote speakers and the hands-on Cloud Showcase, youll get exclusive access to unlimited industry solutions and the latest go-to-market innovations that are shaping the future of tech. And youll get it all Miami Beach-style.

You can find out more info here.

WHEN:May 19th 21stWHERE:San Antonio, Texas

Join us in the scenic Texas hill country for the first North America Micro Focus Universe! San Antonio is one of the oldest and largest cities in Texas and is home to thousands of long-horn cattle, six Fortune 500 companies, and a growing number of next-generation companies that are moving in. This unique venue provides a spectacular backdrop to network and learn from Micro Focus product experts, fellow customers, and partners.

You can find out more info here. There will also be an event in the Netherlands in March.

WHEN:June 22nd 26thWHERE:Honolulu, Hawaii

The International Conference on Cloud Computing (CLOUD) has been a prime international forum for both researchers and industry practitioners to exchange the latest fundamental advances in the state of the art and practice of cloud computing, identify emerging research topics, and define the future of cloud computing. All topics regarding cloud computing align with the theme of CLOUD. we will celebrate our 2020 version of gathering, to strive to advance the largest international professional forum on cloud computing.

You can find out more info here.

WHEN:August 30th September 3rdWHERE:San Francisco, California

VMworld captures the momentum of todays rapidly changing IT environment and puts it within your grasp so you can accelerate your cloud journey to support your business. Transform networking and security for speed and flexibility. Deliver digital workspaces for amazing mobile experiences. Whatever you need to know, youll find the best information, tools, and partnerships to take ITand your power to shape itto the next level.

You can find out more info here.

WHEN:October 5th 7thWHERE:Las Vegas, Nevada

HCTS is the premier forum for executives in the hosting, cloud, datacenter and managed services sectors. The agenda is carefully crafted by 451 Research analysts and industry experts to provide timely, actionable insight into the competitive dynamics of innovation. In addition to analyst and executive sessions, the three-day schedule includes a plethora of networking opportunities that will maximize your time spent in Las Vegas and foster the industry-changing relationships HCTS is known for igniting.

You can find out more info here.

WHEN:November 4th 5thWHERE:Santa Clara, California

The Cyber Security & Cloud Expo North America 2020 will return to the Santa Clara Convention Center in the heart of Silicon Valley on November 4-5 to host its second North American event. It will bring together key industries from across the globe for two days of top-level content and discussion across 5 co-located events covering IoT, 5G, Cyber Security, Cloud, Blockchain, AI and Big Data, energy, financial services, healthcare and more.

You can find out more info here.

WHEN:November 30th December 4th (tentative)WHERE:Las Vegas, Nevada (tentative)

AWS re:Invent is a learning conference hosted by Amazon Web Services for the global cloud computing community. The event will feature keynote announcements, training and certification opportunities, access to more than 2,500 technical sessions, a partner expo, after-hours events, and so much more.

You can find out more info here.

Looking for information on managed service providers for your cloud solutions? Our MSP Buyers Guidecontains profiles on the top cloud managed service providers for AWS, Azure, and Google Cloud, as well as questions you should ask vendors and yourself before buying. We also offer anMSP Vendor Mapthat outlines those vendors in a Venn diagram to make it easy for you to select potential providers.

Check us out onTwitterfor the latest in Enterprise Cloud news and developments!

Dan is a tech writer who writes about Enterprise Cloud Strategy and Network Monitoring for Solutions Review. He graduated from Fitchburg State University with a Bachelor's in Professional Writing. You can reach him at dhein@solutionsreview.com

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The Top 13 Cloud Computing Conferences to Attend in 2020 - Solutions Review

Cloud Security in 2020 Starts With Protecting Data Wherever It Resides – Security Intelligence

2019 saw massive growth in the cloud market. The worldwide public cloud services market is projected to grow 17.5 percent in 2019 totaling $214.3 billion, up from $182.4 billion in 2018, according to Gartner.

Why has there been such a surge in cloud growth? Because as organizations move toward cloud computing, they are benefiting from capital expenditure cost savings and leveraging the flexibility of software-as-a-service (SaaS) solutions. However, as cloud adoption continues, organizations need to ensure they maintain a robust cloud security posture.

To dig deeper into this, as well as inquire about where cloud security will be heading in 2020, I spoke with subject matter expert and IBM Security Program Director for QRadar Cloud, SaaS and MSSP, Chris Collard. Chris is an information security professional with over 15 years of experience managing information systems and services, a Certified Information Systems Security Professional (CISSP) and holds a Certificate of Cloud Security Knowledge (CCSK) from the Cloud Security Alliance.

Question: As we near the end of the year, what are your key takeaways from the 2019 cloud security market?

Collard: We continue to see a growing number of clients solidify and execute on their cloud-first strategies as well as make inroads into migrating applications, data and workloads to the cloud. Increasingly, cloud is the platform of choice for building new applications as well as acquiring new software services.

For those organizations that have already made the transition, often the focus turns squarely to the challenges of effectively monitoring these environments and building orchestration and augmented intelligence into operations and response capabilities.

Nevertheless, even with the significant momentum that has developed throughout 2019, we are still a fair way off from realizing all the benefits of pure cloud deployments. Our IBM Cloud team estimates that approximately 80 percent of production workloads are still not yet migrated to the cloud. This means that a significant set of the opportunities and discussions about cloud security are still in front of many of us.

As organizations prepare for and design their path to the cloud, they absolutely have the opportunity to reimagine business processes and an imperative to protect and secure their data at each stage in the journey including the destination. When we look at the security product and solutions market, we continue to see a fragmented one leaving many organizations to attempt to manage a patchwork of point solutions on-premises and in the cloud.

What organizations ultimately need is a cohesive and well-structured set of solutions able to continuously monitor the compliance of multi-cloud and hybrid environments. When teams can better connect their environments and data, they are better positioned to gain security insights and to take action and respond quickly when required. With a unified approach to security, organizations can gain immediate benefits and be better prepared for security in a hybrid, multi-cloud world.

What is the state of the SIEM-as-a-service market as we near the end of 2019?

Collard: Cloud is increasingly the future of security information and event management (SIEM). The cloud as the platform for SIEM allows organizations to scale better and more flexibly to align with, and meet, the present demands of their business.

Consuming capabilities as a service typically comes with the added benefit of helping free organizations from the responsibility of staffing the range of specialists required to deploy and maintain complex technology stacks. Managing threats is hard enough without having to also manage and maintain on-premises software deployments. When organizations are freed up from nonessential activities, such as managing hardware and software related life cycles, they can re-invest this found time and further focus on more important activities, such as protecting and defending critical corporate data and other important assets.

As this market continues to expand, we expect to see further adoption of open standards for data and applications. The increased adoption of STIX, TAXII and other open standards points to a future built on interoperability and the ability to protect data everywhere it exists. By not adopting open standards, you run the risk of losing visibility into the breadth of your data over time or in limiting your abilities to analyze your data into the future.

What would you say should be the No. 1 priority for organizations moving to cloud security in 2020?

Collard: The short answer is protect your data wherever it resides. The longer answer ultimately depends upon where clients are in their journey, whether they are just embarking on their journey to the cloud or they have already fully adopted the cloud as their deployment platform of choice. Protecting data from loss or leakage is the ultimate goal. To get there, organizations should embrace the opportunity to refresh their overall deployment strategy, from the ground up if necessary, and ensure that this strategy has cloud considerations integrated throughout.

After protecting your data no matter where it lives, what other aspects of cloud security should organizations focus on in 2020?

Collard: While outlining a modernized strategy, you should also take the opportunity to rebuild your security policies. Applying best practices, including a zero-trust security model, can help protect not only your data but also your networks, users, workloads and devices. This strategy should include the definition of microperimeters based on the end-to-end flow of data as well as the employment of microsegmentation, wherein identities and access can be strictly controlled to a granular degree and not just at the level of an entire server or subnet.

Where possible, organizations should look to leverage available cloud-native security controls. These controls can unlock additional visibility into your environments and can be used to further feed SIEM detection capabilities.

Achieving the goal of protecting your data across multi-cloud and hybrid environments also requires a strong DevOps or DevSecOps organization that can help automate, apply and manage your security at the critical intersections within your business. DevOps can play an important policy enablement role within your organization. Through DevOps, you should expect to see your policies and rules enacted with greater speed, velocity and precision.

If you have instrumented your environment correctly, have built the right monitors and have the right processes in place, you should then be effectively positioned to continuously monitor your environments for compliance. Having defined what needs to be filtered out versus kept and what needs to be analyzed versus maintained for posterity, organizations are best positioned to deliver orchestrated incident response.

No matter the size, organizations understand the benefits of migrating data and applications to cloud environments as they see the necessity to leverage cloud infrastructure to elastically scale up, store data in a cost-effective manner and reach a global customer base.

Learn more about securing the cloud

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Cloud Security in 2020 Starts With Protecting Data Wherever It Resides - Security Intelligence

10 Toolbox Stories You Loved in 2019 – Toolbox

This is the whole point of technology. It creates an appetite for immortality on the one hand. It threatens universal extinction on the other. Technology is lust removed from nature. - Don DeLillo, American Novelist

With so much going on in artificial intelligence (AI) and cloud computing world, its hard to find articles and resources which not only inform but educate about the shifts in technologies, career-building tips and accelerate your progress in these fields. At Toolbox, we help you stay current with our coverage of current and emerging technologies and keeping a pulse on shifting technology trends. Needless to say, you ended up loving the content we curated. Heres a look at your favorite picks of 2019 that have staying power.

Table of Contents

1. 5 AI Programming Languages for Beginners in 2019

2. 10 Industries AI Will Disrupt the Most by 2030

3. The Top 5 Cloud Computing Books to Read in 2019

4. How to Build a Career in Artificial Intelligence and Machine Learning

5. 10 Most Common Myths About AI

6. What Is Deep Learning: Definition, Framework, and Neural Networks

7. What Is the Difference Between Artificial Intelligence, Machine Learning, and Deep Learning?

8. What Is Cloud Computing Architecture: Front-End & Back-End Explained

9. Top 5 Private Cloud Service Providers in 2019: HPE, VMware, Dell, Oracle, and IBM

10. 10 Experts on the Future of Artificial Intelligence

Artificial Intelligence, machine learning (ML), and deep learning (DL), are being used to simplify various business processes today. With cloud-based AI solutions, it has become even easier for companies to deploy AI to the average user, thereby paving the way for exciting possibilities.

Note: With so much buzz on AI, how does one get started with it. Check out this ready list of programming languages for AI and ML.

This article explores the fate of the industries that are most likely to be impacted by the wide adoption of artificial intelligence.

Note: Quick snapshot on industries poised for disruption by AI and emerging technologies.

Every aspiring cloud professional should aim to build a good foundation in basic cloud computing concepts. The article provides a compilation of the top 5 books on cloud computing that aims to help readers master the basics and understand the current landscape of cloud.

Note: Planning to learn cloud computing, dont miss out on this carefully crafted book list.

However, with growing competition, it is getting difficult to land a job as a machine learning professional. This article discusses the skills and certifications that are required to get hired as a Machine Learning engineer, AI developer, or a Research Scientist. It shares detailed information about the five sought-after AI and machine learning roles one can choose from.

Note: Short and concise guide on upcoming jobs roles in AI/ML and learning resources.

This article lists some of the most popular myths about artificial intelligence and digs deeper into them. It aims to investigate the real-world implications and possibilities of these theories and makes an attempt to separate hype from reality. Quite an interesting read, this one!

Note: Get real about artificial intelligence with this piece that busts common misconceptions and more.

This article educates readers about the basics of Deep Learning and neural networks, as well as the frameworks that are used to create them. It also lists some examples of neural network algorithms.

Note: This article is your go-to guide on Deep Learning algorithms.

However, due to the growing buzz around artificial intelligence, machine learning, and deep learning, the difference between these terms has become unclear. Due to the similarity of these terms, a lot of new entrants find these concepts confusing. This article aims to help readers differentiate between various artificial intelligence-related terminologies with the help of definitions and helpful examples. Definitely a must-read!.

Note: Stay on top of your concepts and understand the conceptual differences with this article.

This article explains front-end and back-end cloud computing architecture in detail. Lets take a look!

Note: Dont miss out on this ready explainer on cloud computing which is a good read for beginners and techies!

Note: Find out whos on top of the stack in the cloud computing world.

Various companies that have been early adopters of AI solutions have been able to see significant gains in the optimization of their business processes. Artificial intelligence is seeing wide adoption in the enterprise sector. However, professionals who have not yet adopted AI are clueless about how the technology actually works and what its future will be like.

Therefore, the only way to gauge the effect of AI on various industries is to talk to professionals who work with this technology on a daily basis. Toolbox reached out to industry experts to understand their views about the future of artificial intelligence. Take a look at the compilation.

Note: Check out the top 10 predictions on the future of AI by industry experts and what are the next steps in industry adoption.

What would you like us to write about in 2020? Comment below or let us know on LinkedIn, Twitter, or Facebook. Wed love to hear from you.

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10 Toolbox Stories You Loved in 2019 - Toolbox