Free Time and Free People – lareviewofbooks

JULY 15, 2020

To findLARBs symposium onMartin HgglundsThis Life: Secular Faith and Spiritual Freedom, click here.

ACCORDING TO MARTIN HGGLUND, Marx provides us with the greatest resources for developing a secular notion of freedom. This assessment hinges on two claims. First, a commitment to individual freedom is the foundation of Marxs work. Second, Marxs particular development of the idea of freedom is more fecund for the project of caring for the secular world than any other. In other words, freedom was central for Marx, and Marx ought to be central for our understanding of freedom.

I am very much in agreement with both of these headline claims, and, therefore, very sympathetic to Hgglunds project. But the devil is in the details, and I would like to specify both what freedom meant for Marx and what Marx might mean for our freedom struggles in slightly different terms than Hgglund does. To sum it up in a phrase, I want to prise open a distinction between two interpretations of Marx: Hgglunds Marx, the democratic socialist; and my Marx, the social republican. I then want to ask whether these two Marxes might be married or, at least, made to cohabit without being conflated.

In order to do this, I will pursue three questions: one Marxological, one conceptual, and one political. (1) Is Marxs commitment to the free development of individualities identical with his commitment to individual freedom? (2) Is the socialist critique of liberalism fully immanent, in the sense that it simply exposes liberalisms own self-contradictory attachment to forms of social mediation that thwart the liberal commitment to individual freedom? (3) Are the political institutions of socialism best understood as how we express our priorities and our conception of value? I think the answer to each of these must be no, and that this entails some significant but friendly amendments to Hgglunds democratic socialism.

1.

As Hgglund eloquently argues, the free development of individuals what Marx called real freedom depends upon free time, or how much time we have to lead our lives. Free time, as Hgglund also argues, is not idle time, or time free from work, free from commitment, or free from the constraints that come with work and commitment. Rather, free time is that surplus of time in which we can commit ourselves to the work we want to do for its own sake. Attention to this the human use of free time is the beating heart of Hgglunds book.

The only consideration I want to add is this: being subject to a dominating power means that your time is not your own, and that your time is, therefore, not free. This is obviously true of the enslaved, who have no free time even when they have no work to do since they are always at the beck and call of the slaveholder. But think also of the time- and attention-consuming maneuvers and activities women undertake on a daily basis to avoid sexual assault and harassment in our male-dominated society. Vulnerability to alien power degrades time, eating it up with anxieties and strategies.

I introduce this consideration in order to stave off an easy misunderstanding of Marxs distinction between the realm of necessity and the realm of freedom. If we ask how the line between the two realms is drawn, or what might allow people to move it in one way or the other, there is a temptation to focus on three factors: technology, labor exploitation, and ethics. From within this framework, the realm of necessity may be reduced by applying labor-saving technology, by reducing or eliminating the coercive appropriation of other peoples labor, and by refusing to treat all my activities merely as means.

What goes missing from this reading of the freedom/necessity distinction is Marxs denial that the modern ruling class of capitalists enjoys free time, and that this absence of freedom among the ruling class is not due to insufficient technology, the exploitation of the capitalists labor, or to an ethical lapse on their part. This class is made up of rough, half-educated parvenus, as Marx puts it, not the free persons of antiquity, because capitalists are market-dominated producers, attentive to the shifting whims of supply and demand, and consequently anxious to accumulate lest they go under.

Marx wants to turn this fact to the advantage of the workers movement. Labor organizations should fight for shorter working days in order that the workers themselves will have the time and resources to educate and develop themselves politically, but also so as to keep the market pressure on capitalists high. This will, Marx argues, speed both the development of productive technology, as competition on productivity heats up, and the concentration of capital, as less capital-intensive firms go under. This strategy hinges on the capitalists domination by the market and consequent lack of free time.

Market domination, therefore, is central to Marxs understanding of the dynamics and harms of the capitalist mode of production. His arguments in this regard can, and should, be extended. If domination by the market corrodes and destroys free time, this is not because of some special quality of the market but because of the typical quality of domination. I am dominated wherever I am vulnerable to uncontrolled interference from another or others, whether or not they exercise their power of interfering. Being dominated gives agents a special set of reasons to consider in their actions: How will my dominator(s) react to what I am doing? Will they use their power against my projects? How? Regardless of what I want to do, a new sort of uncertainty or anxiety hangs over my plans, intentions, and desires. Therefore, to Hgglunds argument that anyone who is committed to being an agent is committed to increasing her realm of freedom and decreasing her realm of necessity, we can add that she is equally committed to decreasing the domination to which she is subject.

For this reason, it is not enough for Marx to say, as he does in the manuscript for Volume Three, that increasing the realm of freedom requires, as a prerequisite,

socialised man, the associated producers, rationally regulating their interchange with nature, bringing it under their common control, instead of being ruled by it as by the blind forces of nature; and achieving this with the least expenditure of energy and under conditions most favourable to, and worthy of, their human nature.

It is crucial to add, as he did in Volume One, that the shape of the social life-process, i.e., of the material production process, only strips off its mystical haze when it becomes the product of freely associated human beings, standing under their conscious, methodical control.

What is really distinctive about Marxs political project is not his desire for capacious and equitably distributed free time, or his belief that we should exercise conscious, methodical control over the material production process. These are widely held socialist goals. What is distinctive is that he holds free association among producers to be the fundamental precondition for both of these goals. Marxs free association evokes the free city of republican thought, an association of people, insulated from dominating power, who cooperate in ordering their social and natural world. This is what Marx following the working-class militants of 1848 called the social republic, or the republic of labor. It is a social republic because it extends republican government the republican and beneficent system of the association of free and equal producers into the heart of society, the factories and workshops.

None of this contradicts anything in Hgglunds reconstruction of Marx. But it is absent, and I worry that its absence betrays an apolitical tendency in Hgglunds democratic socialism. Individual freedom, for Marx, was both the freedom to develop ones powers and capacities in an open-ended way and the freedom from domination that is the prerequisite for free development. Association free from domination is the political basis of socialism on Marxs account.

Hence, my answer to the first question: individual freedom from domination ought not be identified with the free development of individualities, since it is a prerequisite of this free development.

2.

Even with this amendment, my argument supports Hgglunds contentions that individual freedom is of fundamental importance to Marx, and, further, that this underscores the proximity between Marxian socialism and liberalism. At several points in This Life, Hgglund portrays this proximity in Hegelian fashion: Marxs critique of liberalism is an immanent one that takes liberalisms own principle individual freedom and shows how this principle is incompatible with liberalisms commitment to capitalism. Liberals must choose, then, the true object of their fidelity: freedom, or capitalism?

I am resistant to this move, however. It makes liberals out to be either socialists-who-havent-yet-realized-it or bad-faith actors, who talk about freedom, but actually care only about higher rates of profit. I certainly think there are some liberals who fit each of those descriptions, but I also think that there are liberals who understand freedom in a genuinely different way. The disagreement between liberals (of this sort) and socialists (of Hgglunds sort) is deeper than Hgglunds presentation lets on, and, therefore, Hgglunds critique does not, I think, touch these liberals in the way that an immanent critique aspires to.

Hgglunds text betrays what I think is the real fault line, in chapter six, when he claims that Hayek reduces freedom to liberty. By this, Hgglund means that Hayek believes people are free so long as they are not directly coerced. This distinction between freedom and liberty, however, appears nowhere else in Hgglunds book. This passage, therefore, seems to evince a slight anxiety about how Hayek fits in to the immanent critique of liberalism.

This anxiety is reinforced by the surrounding argument. Hayek comes up in the course of Hgglunds argument that the major liberal thinkers of political economy Mill, Rawls, Keynes, and Hayek unwittingly concede that the capitalist measure of wealth distorts the values to which they themselves are committed. According to Hgglund, the tension (or contradiction) between the capitalist measure of wealth and the values held dear by liberals is resolved, at the level of theory, by the dream of what Mill called the stationary state. The stationary state, according to Hgglund, is the imaginary point at which capitalism and the profit motive will have done the work they need to do increasing the technological powers of production and the wealth of the world and can be set aside for the sake of living a more satisfying or fulfilling life, pursuing higher and more noble ends than making more money. Liberals like Mill, Keynes, and Rawls are compelled to posit some such end of capital accumulation, according to Hgglund, for it is only thereby that they can square their actual, substantive values with the existence of a social system that subordinates all values to the pursuit of surplus-value.

Hayek, however, does not dream of a stationary state. And so, when Hgglund come to Hayek, he is forced to change tack, and he introduces the freedom/liberty disjunction in place of a discussion of Hayeks imaginary resolution of the contradiction. This should make us pause. After all, Hayek is not the only liberal thinker of political economy that refuses the stationary state. Adam Smith saw the stationary state a country that had attained the full complement of riches which [] its situation [] allowed it to acquire as a fateful eventuality, in which both the wages of labour and the profits of stock would probably be very low. For Ricardo, the stationary state was a threat, something to be avoided by liberalizing the economy and increasing the volume of trade. For Herbert Spencer, social evolution had no upper limit, and liberal policy would ensure continuous growth and progress. For Chicago School neoliberalism, the growth of value is synonymous with innovation, and a steady-state economy is, therefore, synonymous with a world in which there are no new ideas, or no opportunity to communicate new ideas. Paul Romer, who won the Nobel Memorial Prize in Economics, has pushed this line of argument the furthest.

In short, there is a long tradition of liberal thinkers of political economy a tradition of which Hayek is, in many respects, representative that do not evince any of the conflicted feelings about perpetual economic growth that Hgglund finds in Mill, Keynes, and Rawls. Even if the socialist critique of the Mill-Keynes-Rawls line of liberalism is wholly immanent, it does not follow that the socialist critique of the Smith-Spencer-Hayek line will be. I think this is what lies behind Hgglunds sudden introduction of the freedom/liberty distinction: the intuition that the liberal commitment to individual freedom is not, in the case of Hayek, et al., at odds with the liberal commitment to capitalism.

So what is going on here? If I were to briefly characterize this other liberal tradition, I would say that its center of gravity is a categorical opposition to private coercion and violence. It accepts the need for a central state because centralizing coercive force allows for its deployment to be regulated by commonly acknowledged laws. When the rules for deploying force are simple, universal, and public, and discretionary coercion is minimized, then two things happen. First, people are compelled to enter into voluntary exchanges and contracts in order to pursue their aims. Second, concentrations of power and resources become not only harmless but salutary, since they allow people to do new and creative things even while they do not since the private use of force is off the table give the wealthy and powerful the ability to hold sway over the poorer and less powerful. Even monopoly power, on this view, is not a problem unless it is over basic necessities since, in an otherwise competitive market environment, monopoly prices spur innovation and the entry of other suppliers into the market. State capture is a consistent concern, however, since that is where the coercive power lies.

This strand of liberalism is not obviously touched by Hgglunds immanent critique, for Hayek is neither half-hearted in his embrace of the profit motive nor disingenuous in his commitment to individual freedom. So long as profit-seeking behavior remains within the bounds set by the law, Hayek does not think it is incompatible with any liberal values at all. So long as the state is restricted to promulgating simple, universal rules and providing basic public goods, Hayek thinks that the freedom of each is compatible with a similar freedom for every other.

To be absolutely clear: Marx is critical highly critical of this sort of liberalism! But his critical confrontation with it takes place on the grounds of the historical dynamics of the capitalist economy and of political struggles over power, not at the level of its adherence to shared principles. Marx and Hayek disagree about how the world works. This disagreement and the conditions under which it might be adjudicated are obscured, I think, by focusing on the supposed contradiction between the value of free time and the capitalist measure of social wealth. And this has consequences for how we think about socialist politics, consequences to which I will now turn.

3.

One of the most important contributions of Hgglunds book is that it demonstrates how central the economy of time is to Marxs thought. This has been neglected on the left, and its neglect has given rise, as Hgglund points out, to the theoretically and politically disastrous conflation of overcoming capitalism with overcoming finitude. Adorno is not the only critical theorist to pine for the utopia of absolute plenitude, or to treat scarcity as the necessary and sufficient cause of class domination. As Hgglund rightly argues, this particular species of utopia is not merely unattainable, but undesirable and incompatible with the fragile possibility of freedom.

An interesting side-effect of Hgglunds reading of Marx is that it highlights a heretofore neglected point of contact between Marxs critique of political economy in the 1850s, 60s, and 70s, and the marginal utility theory that was simultaneously revolutionizing bourgeois economics. Marginalism, and the neoliberal economics that grew out of it, take the scarcity of time to be one of the most fundamental axioms of economic analysis. Perhaps Marx and the marginalists are much closer to one another than anyone has appreciated. (Even I. I. Rubin, who undertook the best examination to date of the relation of Marxism to marginalism, says nothing about time as a category.) I am not in a position to stage this confrontation here, but I do want to explore a political dimension of the question.

The economy of time does not work the same way in all contexts. In particular, it matters whether we are talking about (a) an individual agent prioritizing and pursuing their own projects, (b) a group of agents agreeing to prioritize and pursue a set of common projects, or (c) a number of agents, individual and/or collective, trying to accommodate one anothers various projects without agreeing upon an overarching set of priorities or a common project. Call these, respectively, the situations of (a) individual action, (b) collective action, and (c) coordination. My concern is that Hgglunds construal of democratic socialism tends to treat the economy as a problem of collective action, and thereby covers over the special problems of coordination. In this way, Hgglunds democratic socialism reproduces, in inverted form, one of the major shortcomings of neoliberal theory. Neoliberals often act as if coordination can and should crowd out all collective action. Socialists should not make the opposite error of thinking that collective action can and should crowd out all coordination.

The basis for my concern is that Hgglund seems to presume a correspondence between the purposes pursued by subsystems in the economy and the purpose of the economy as a whole. So, for example, Hgglund slides from saying that [u]nder capitalism, the purpose of our economic production is already decided, to saying that what matters above all is to generate a growth of capital in the economy. However, the purpose of production at the level of the individual firm is not to generate growth in the economy as a whole, but to secure a profit sufficient to stay in business for another quarter, or to increase market share, or the like. The growth of capital in the economy as a whole is supposed to be a by-product of good institutional design and a free market, not an additive result of everyone pursuing and attaining profit. Individual producers and firms are just as profit-motivated during a depression as they are during a boom, but the depression is marked by a contraction of capital in the economy. Even in a booming economy, many businesses will fail to make a profit, and many people will pursue projects that are not even remotely likely to realize a profit. Macroeconomic policy and performance are not tightly chained to much less epiphenomenal of microeconomic motivations.

The imperative of economic growth is strong, I agree, but it is not due to an isomorphism between subsystems and system. Rather, it is a governmental imperative. On the one hand, liberal governance only seems to work under conditions of economic growth. Recession and stagnation bring increased social conflict, and, with them, increasingly authoritarian and conflictual politics. On the other hand, securing the conditions for capital accumulation are necessary in order to prevent capital flight and the collapse of both tax revenues and the ability of the government to finance its operations on the bond market.

As a consequence of seeing the macroeconomy as an expression of the microeconomy, when Hgglund turns to outlining the case for and principles of democratic socialism, he often writes as if democratic socialism will require both an ethical transformation on the part of everyone and a single collective decision-making process about how to structure the economy. Thus, he tells us that [t]he first principle of democratic socialism is that we measure our wealth both individual and collective in terms of socially available free time. This seems to imply that everyone in a democratic socialist state must be a democratic socialist, or that every individual measure their wealth in terms of socially available free time. Similarly, the second principle of democratic socialism collective ownership of the means of production implies, for Hgglund, that we cannot have private property in the abstract sense that transforms property into a commodity that can be bought and sold for profit.

Hgglund rightly criticizes Fredric Jameson for excluding institutions of freedom from his vision of socialism. But I would challenge Hgglund to amplify this insight. Institutions of freedom do not simply decide upon common purposes, and are not, therefore, exhausted by collective projects of self-determination. Institutions of freedom also include processes by which we negotiate not to collectively determine our purposes and come to terms with one anothers projects without trying to fit them into some overarching common pursuit.

I believe that Hgglund would agree with this inclusion of institutions of coordination among the institutions of freedom. He is explicitly sensitive to the fact that our practical identities and their order of priority [] must remain at issue and possible to change. He also insists, rightly, that the exercise of spiritual freedom must include the possibility of criticizing or rejecting the established forms of participation. Both of these principles imply that consideration of the public good must be agnostic about certain elements of individual and collective agents pursuits.

But what I want to push is (a) that this public agnosticism about how people lead their own lives is going to have to extend to people buying and selling property for profit, and (b) that this buying and selling property for profit should not be made into the substance of capitalism. There is every difference in the world between saying that socialism is incompatible with commodities being the general form of wealth, and with labor-power being a commodity, on the one hand, and saying, on the other, that socialism is incompatible with the existence of commodities, buying and selling, and profit. The former is compatible with the perspective of spiritual freedom Hgglund defends. The latter is not it is too perfectionistic and moralistic in its conception of what makes capitalism and socialism the systems they are.

4.

This brings me, finally, back around to Marxs relation to liberalism. In the second section of this paper, I emphasized liberalisms categorical opposition to private coercion. Implicit in the third section was another feature of liberalism: its specification of the public sphere as the sphere in which divergent projects are accommodated. This is just the flip side of the abhorrence of private coercion, since it attempts to remove the power of coercion from any agent or group pursuing any particular project, and to reserve it for the public authorities who are supposed to ensure only that everyone can go about their own business.

Marxs social republicanism which I outlined in the first section relaxes the liberal stricture against non-state actors using coercive force; it is hospitable to the collective efforts of the dominated to coercively oppose their domination. But, for the same reason, it is congenial to the liberal notion that the public authority should not be treated like an enterprise association of the whole population. The states claims to manifest the popular will evince, in Marxs words, a cult of the people that occludes the forms of social domination that divide the people against itself.

In this way, Marxs social republicanism pulls against democratic socialism. We can put it in the form of a dilemma. If the democratic state exists, with its invocations of popular self-determination, then so does capitalism, with its particular form of class domination. If, on the other hand, social life is permeated by democratic decision-making, then the state, with its fictive unity and its attendant imaginary of the sovereign people, withers away. The various local communities, and their federation under higher national and international elected bodies, will differ from one another in what they want to pursue, and these local, national, and international authorities will also come into conflict with the various democratically managed workplaces. There will be no single, unitary forum in which these conflicts will get ironed out, by democratic deliberation, into one plan for the economy.

This, to me, is the blind spot of all democratic socialism, a blind spot it shares with much democratic theory. Neither before nor after the construction of socialism is there a single forum in which we would take definitive decisions about the form of our life together or about the purpose and practice of our economy. Institutions of coordination markets, constitutions, electoral parties, contestatory elections, bargaining fora will have to knit together the various collective and individual agents. Democracy, from this perspective, is critically important as a check on these institutions of coordination, to keep them from dominating the forms of life that they are supposed to enable, just as it is crucial within the various collective projects. But democracy cannot constitute a single collective agent, responsible for organizing and legislating the form of our life together.

At its best, political democracy allows the organized masses to control what political officeholders can or cannot do with their institutional power. This is a wonderful thing, for it frees the organized masses from the political domination of the state, replacing the haughty masters of the people by always removable servants. But democracy always remains a way of checking and controlling power; it is never a mode of collective self-legislation or self-expression.

To read Martin Hgglunds response to this essay, click here.

William Clare Roberts is associate professor of political science at McGill University. He is the author of Marxs Inferno: The Political Theory of Capital (Princeton University Press).

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Free Time and Free People - lareviewofbooks

Ten books to read in July – Albany Times Union

The best thing about social distancing? You have a valid excuse to stay home and read. Of course, some establishments are reopening, and that includes bookstores. Patronize them when you can and remember to wear a mask when you do. You'll want to be safe and courteous as you check out July's bumper crop of new titles.

"Say It Louder!: Black Voters, White Narratives, and Saving Our Democracy," by Tiffany D. Cross (July 6)

Cross is a veteran news analyst whose time on the campaign trail has convinced her that black voters can shape the future of the United States if they are not silenced. She examines the paradox of a system designed to exclude black lives that would not exist without them.

"Notes on a Silencing: A Memoir," by Lacy Crawford (July 7)

Sexually assaulted at 15 by two fellow students at a prestigious prep school, Crawford spent years putting her past behind her. But when she found out she wasn't the only victim, she came forward, only to learn about the extensive and sustained efforts by school leaders to cover up a culture of abuse.

"The Vapors: A Southern Family, the New York Mob, and the Rise and Fall of Hot Springs, America's Forgotten Capital of Vice," by David Hill (July 7)

Hill, a native of Hot Springs, Ark., takes readers back to the 1930s to '60s, when that city was as rife with gang activity as Las Vegas or Miami. When Owney Madden came to town and decided to open a resort called The Vapors, casinos, brothels and racetracks followed. Hill interweaves this history with first-person accounts, including one from his grandmother.

"Antkind: A Novel," by Charlie Kaufman (July 7)

Once you enter the world of protagonist B. Rosenberger Rosenberg, who has seen a three-month-long film masterpiece that no one else has, you won't be able to extricate yourself until the 700-plus-page novel is finished. Kaufman (the screenwriter of "Being John Malkovich," "Anomalisa" and "Eternal Sunshine of the Spotless Mind") crafts a mind-bending fever dream that's also a ripping good read.

"Want: A Novel," by Lynn Steger Strong (July 7)

Despite a PhD, a husband and kids, Elizabeth feels like she's reached a dead end: She's bankrupt and can't find a job in academia, while her husband struggles to get his carpentry business off the ground. But when she reconnects with her childhood friend, Sasha, old patterns resurface alongside an overwhelming desire for complete fulfillment.

"Utopia Avenue: A Novel," by David Mitchell (July 14)

This rock-opera of a book follows Utopia Avenue, a bizarre band whose members include Jasper de Zoet (yes, a descendant of the title character in Mitchell's "The Thousand Autumns of Jacob de Zoet," set in 17th-century Japan). Mitchell's rich imaginative stews bubble with history and drama, and this time the flavor is a blend of Carnaby Street and Chateau Marmont.

"Twilight of Democracy: The Seductive Lure of Authoritarianism," by Anne Applebaum (July 21)

Please listen to Applebaum, and not simply because she was previously a columnist at this newspaper. She's been sounding alarm bells about anti-democratic trends in Europe for a long time, and as an acclaimed historian of the Soviet Union (she won a Pulitzer in 2004 for "Gulag: A History"), Applebaum understands how and why authoritarianism takes hold.

"Hamnet: A Novel," by Maggie O'Farrell (July 21)

Imagine that a penniless Latin tutor married to a somewhat wild woman had a son they loved to distraction, who died of a plague. His name was Hamnet and a few years later the tutor would pen a play titled "Hamlet." But that's really as far as O'Farrell goes with the Shakespeare stuff in this brilliant examination of grief and family bonds.

"Afterland: A Novel," by Lauren Beukes (July 28)

Three years after a pandemic known as The Manfall, the world is run by women. Is it a better place? Not for mothers like Cole, who will go to any length to protect her 12-year-old son from a fate as a reproductive resource, sex object or "stand-in son." To evade Cole's sister, mother and son must race across a United States transformed by imbalance and despair.

"Memorial Drive: A Daughter's Memoir," by Natasha Trethewey (July 28)

When a poet writes a memoir, take note. When that poet is Trethewey, former poet laureate of the United States, start reading immediately. The author was 19 when her stepfather shot and killed her mother at their home in Atlanta. While the book grapples with personal pain, its expansion into the societal ills of racism and domestic abuse lifts it to a new level of urgency.

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Ten books to read in July - Albany Times Union

Three new cases of COVID-19 on Grand Bahama – Bahamas Tribune

The Ministry of Health confirmed on Saturday that there are three new cases of COVID-19 in Grand Bahama.

The new cases are:

A 16-year-old girl with a history a travel.

A 47-year-old woman with no history of travel

A 39-year-old woman with a history of travel.

All three are in isolation at home.

The total number of cases now stands at 111 with 11 of those active.

Health officials are reminding the public to practice the following measures to prevent the spread of COVID-19:

Wear a face mask when you leave home;

Wash your hands often with soap and water for at least 20 seconds, and if soap and waterare not available, use an alcohol-based hand sanitizer with at least 70% alcohol;

Cover your cough or sneeze in your inner elbow or with a tissue; and

Clean and disinfect frequently touched surfaces such as phones, remotes controls, counters,doorknobs, and keyboards.

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Three new cases of COVID-19 on Grand Bahama - Bahamas Tribune

47th Independence Celebration, A Display of Innovation and Creativity – The Eleutheran

Royal Bahamas Police Force, 47th Independence Anniversary, Clifford Park.

The Independence Celebrations Committee in conjunction with the Bahamas Christian Council marked the countrys 47th Anniversary with an innovative made-for-television virtual programme that kept Bahamians entertained from start to finish, showing abundant young talent in a four-hour special.

The virtual show was created to adhere to protocols to avoid spread of the COVID-19 pandemic. For the first time in the nations Independence history, Bahamians could not gather together on Clifford Park to celebrate and anticipate the Flag Raising at midnight, and fireworks, to bring in Independence Day.

Two events, pillars of the traditional celebration, were held at Clifford Park: the Ecumenical Service to begin the programme, Thursday evening, July 9, and Flag Raising and Fireworks at midnight to mark the dawn of Independence Day, July 10, 2020.

Most of the programme was anchored at studios of the Broadcasting Corporation of The Bahamas, and comprised a jubilant, creative showcase, with occasional greetings from Bahamian nationals in other countries via ZOOM all viewed from the comfort of home.

From Clifford Park, President of the Bahamas Conference of the Methodist Church and Third Vice-President of the Bahamas Christian Council, and Savannah Sound, Eleuthera native, Reverend Carla Culmer delivered the charge to the theme, Pressing Onward: A Time of Hope, Triumph and Transformation. In the charge, she called for continuance of the hopefulness, resilience, and community togetherness that have helped sustain Bahamians over the years.

At the end of the night, the Bahamas Christian Council and uniformed branches at Clifford Park conducted the Flag Raising. And Fireworks signaled the long awaited moment to celebrate at dawn of Independence Day, July 10, 2020.

Source:Bahamas Information Services(BIS Photos/Patrick Hanna)July 11, 2020

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47th Independence Celebration, A Display of Innovation and Creativity - The Eleutheran

DraftKings Matches FanDuel With Introduction Of Separate Casino Games App In PA – Penn Bets

DraftKings customers can now use a stand-alone app to play casino games in Pennsylvania.

The company announced the launch of the app Tuesday, which gives players a new option on their phones instead of navigating through the same site they use for sports betting and daily fantasy sports.

The move comes on the heels of DraftKings doing the same thing in New Jersey with a separate casino app launched June 23. On that same day, competitor FanDuel introduced its own casino app in Pennsylvania so customers wouldnt have to go through its sportsbook site to play.

DraftKings is primarily known for its sports betting and fantasy sports, but in April it introduced its casino product to Pennsylvania. Its casino games embedded on the sportsbook site took in $3.7 million in revenue in May, sixth best out of the iGaming sites in the state. FanDuels online casino, which had a head start several months earlier, earned $8 million.

Up to now, the DraftKings casino site, operating under a skin from Hollywood Casino, has had 29 slot options, four roulette games, blackjack, baccarat, and video poker.

$250 Bonus

Only 1x Wager Applies, Playable in PA Only

iGaming fans in Pennsylvania will now have the opportunity to experience a more holistic product suite and dynamic gaming experience in a DraftKings-created casino app, a press release from DraftKings announced.

Like in New Jersey, the app features new games only found on DraftKings, plus revamped classics, including blackjack and roulette. In addition to popular slot and table games found only on DraftKings Casino, the new app will also offer games from third-party providers like International Gaming Technology. DraftKings customers in Pennsylvania will soon have access to the custom DraftKings Live Dealer Studio which will operate 24/7.

Live dealing of blackjack and other games has been popular in New Jersey on iGaming sites for some time, but the requirements involved in creating that studio system in Pennsylvania has delayed its introduction in the state for now.

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DraftKings Matches FanDuel With Introduction Of Separate Casino Games App In PA - Penn Bets

9 Black-Owned Burger Joints In North Texas. – Central Track

As we now know four months into this pandemic, COVID-19 is disproportionately affecting people of color in a multitude of ways one of the biggest being economically. Systematically, black and brown bodies are shoved into neighborhoods that are economically unfounded and often in food deserts with little to no regard for food insecurity

After Latinos, African-Americans are the second most Coronavirus-affected community. On top of that, Black-owned businesses have been put at a severe disadvantage due to the pandemic, and many may not be able to bounce back from the financial toll this has taken on small businesses.

In efforts to fight this, a popular tool amid the pandemic and to a further degree the shifting cultural climate is the downloading of apps that are essentially directories of Black-owned businesses. A prominent app for finding new food is EatOkra, which highlights Dallas as a popular food destination where users can search for a variety of everything from Vegan eats to Soul food. In times of racially-conscious consumerism, apps like these go a long way in helping to keep Black-owned businesses afloat during this time of uncertainty.

Another favorite among such apps is, of course, burgers, and Dallas is not in short supply of eateries offering up some of the best. The tasty spots listed below are worth the hype that Dallasites seem to praise with every bite.

Wayback Burgers is a franchise with locations stretching across the world from the Netherlands to Africa. However, the Farmers Branch location is Black-owned. Wayback offers a wide selection of burgers along with chicken sandwiches and a ton of sides to share the onion rings are a must-try. Currently, they are only open for takeout.

Brickhouse Burgers is a little burger spot hidden away in a shopping center on Skillman street. This joint offers a wide variety of burgers and sandwiches to pick from, including vegetarian-friendly choices like black bean patties. Craving something sweet after? Try one of the restaurants lauded Mega-Milkshakes like the Candy Crush. For now, Brickhouse is are only open for takeout.

BurgerIM is a franchise across America with a location in the historic West End owned by Wesley Williams. BurgerIM has a wide variety of specialty burgers like the Hawiian Salmon burger and the Falafel burger. For the less adventurous eaters, theres also a build-your-own burger with seven different options, including vegan patties, as well as a gluten-free bun. At this time, BurgerIM is only open for takeout and delivery at this time.

Fatburger is a franchise with locations across the country, but the North Richland Hills location is Black-owned. As the name suggest, this spot has a wide variety of fat burgers. Fatburger also offers vegan and vegetarian patties, as well as vegan milkshakes for the dairy-free crowd. This restaurant is open in all capacities right now.

Wingfields Burgers is tucked into an unsuspecting little spot in Oak Cliff, and is known for serving an iconic duo of breakfast and burgers. Open since the 80s, this Dallas food institution is a must-have among the North Texas food scene. Aside from the thick and juicy burger selection, eaters rave about the thirst-quenching lemonade.

Jimmys franchise may not be Black-owned, but the Arlington location certainly is! This outpost offers up to 25 different types of burgers to pick from, as well as a chicken-based options and a hefty selection of sides. Regulars gush about the homemade taste and generous potions. Jimmys is only open for takeout at the moment.

Though its a small hike out to Duncanville, The Coaches Box is a hidden gem worth the trek. The restaurant doubles as a sports bar and boasts a huge menu with wide selections of burgers, wings and sandwiches. Currently, though, it is only open for takeout.

Also out in Duncanville is Hav-R-Charburger, a vibrant, artful diner crafting the best of American cuisine in classic char burgers, chicken tenders and hot dogs. Though its known for long wait times, that hasnt stopped Hav-R-Charburger from being a Dallas-area favorite. Besides, isnt that the sign of a meal well worth it? Due to the pandemic this joint is only open for takeout and delivery.

Dont let BlackJack Pizzas name fool you, this Dallas mainstay over on Martin Luther King Jr. Boulevard is a burger haven. Beyond its extensive pizza menu, it also boasts a variety of burgers that has Dallasites waxing poetic. Not to be confused with a restaurant chain of the same name, Terry Jones has been serving up pizza and burgers to the community for more than 30 years. As of right now, BlackJacks is only open for takeout.

Cover photo via Brickhouses Instagram.

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9 Black-Owned Burger Joints In North Texas. - Central Track

Play Modernised Versions of Your Favourite Games Thanks to Live Casino – TheUSBport

We all love a quick hand of Blackjack, or spin or two on the Roulette wheel, whether it be at a land-based casino on Saturday night out on the town, or from the comfort of our own home. However, youve got to admit that its about time these games got spiced up a little! Well, with the help of live casinos online, you can now play modernized, live-action versions of your favorite games! Read on to find out more.

The concept of Roulette whether it be European, French, or American version has remained the same, since it was created by Blaise Pascal in the 17th century it has most definitely survived the test of time! However, thanks to Playtechs Quantum Roulette, the age-old classic has been given a much-needed boost into the modern world!

Roulettes odds have never been an issue, with the chance of winning up to 35x your wager. Although, with this innovative creation, you can now land up to a whopping 500x your bet!

Hows that even possible we hear you ask? Well, read on to find out.

Quantum Roulette is played on a standard European wheel this means that it boasts a range of 37 numbers, ranging between 0 and 36. You enjoy a spin on the Devils Wheel from as little as 20p, or right up to 500 ideal for the high-rollers!

Alongside the standard straight up bets which is the method of betting only on a specific number Quantum Roulette also has mouth-watering multipliers! Every time the wheel spins, a number is chosen a random by a quantum strike, sometimes more than one number at a time. Any number that is struck will be enhanced by a multiplier these are also chosen at random and can top 500x your wager!

Quantum prizes can only be won on straight-up bets, or straight up bets using the neighbors system. If the Roulette ball lands on your number, and its been enhanced by a quantum striker, your stake will be boosted by whatever multiplier is on display! The excitement of Roulette has suddenly gone up a notch, right?

Youve guessed it! Playtech has pulled it out of the bag once again, taking the best bits of a centuries-old game and adding in a few new twists and turns. Just like in all versions of Blackjack, the aim of the game is simple: beat the dealer! To get started, a wager between 1 and 500, and youll then receive two cards the dealer will then also receive two cards, one face-up, one face down. This is the point where you hit take another card or stand stick to your initial hand.

As always with Blackjack, you can also split pairs and double down on totals of 11 or under. However, the multiplier cards are what really make Quantum Blackjack different from your standard games. Before the cards are dealt with, between one and three multiplier cards will be given. These are shown in the top right corner of the screen, and can help boost your winnings by 3x, 5x, or 10x!

Basically, if youre dealt a multiplier card, and you win the hand, your prize will be enhanced. If a winning hand contains more than one multiplier card, your payout is boosted by the result of one value multiplied by another! And thats not all if youre lucky enough to have all three multiplier cards in your winning hand, then your payout will be enhanced by a whopping 1,000x!

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Play Modernised Versions of Your Favourite Games Thanks to Live Casino - TheUSBport

Genetic Engineering Market Growing Rapidly with Significant CAGR, Leading Players, Innovative Trends and Expected Revenue by 2025 – Cole of Duty

The Latest Research Report on Genetic Engineering Market size | Industry Segment by Applications, by Type, Regional Outlook, Market Demand, Latest Trends, Genetic Engineering Industry Share & Revenue by Manufacturers, Company Profiles, Growth Forecasts 2025. Analyzes current market size and upcoming 5 years growth of this industry.

The report presents a highly comprehensive and accurate research study on the globalGenetic Engineering market. It offers PESTLE analysis, qualitative and quantitative analysis, Porters Five Forces analysis, and absolute dollar opportunity analysis to help players improve their business strategies. It also sheds light on critical Genetic Engineering Marketdynamics such as trends and opportunities, drivers, restraints, and challenges to help market participants stay informed and cement a strong position in the industry. With competitive landscape analysis, the authors of the report have made a brilliant attempt to help readers understand important business tactics that leading companies use to maintainGenetic Engineering market sustainability.

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Global Genetic Engineering Market to reach USD XX billion by 2025.

Global Genetic Engineering Market valued approximately USD XX billion in 2017 is anticipated to grow with a healthy growth rate of more than XX% over the forecast period 2018-2025. The major driving factor of global Genetic Engineering market are surging utility of technologies such as CRISPR, Talen & ZNF and rising focus on innovation in Gene Therapy in Genetic Engineering. In addition, increasing funding for research and development of medical products is the some other driving factor that drives the market. However, one of the major restraining factors of Genetic Engineering market is high amount of investment. Genetic engineering is also known as genetic modification or genetic manipulation. It is the direct manipulation of an organisms genes using biotechnology. It is a set of technologies used to change the genetic makeup of cells, including the transfer of genes within and across species boundaries to produce improved or novel organisms. Genetic engineering allows of plant or animals to be modified so their maturity can occur at a quicker pace. Genetic modification can also help to create resistance to common forms of forms of organism death. Genetic engineering can also change the traits of plants or animals so that they produce greater yield per plant. Any genetic mutation caused by environmental mutagens may also be corrected through genetic engineering.

The regional analysis of Global Genetic Engineering Market is considered for the key regions such as Asia Pacific, North America, Europe, Latin America and Rest of the World. North America has dominate the market of total generating revenue with 40% across the globe in 2016 due to increasing use of genetic engineering for use of gene therapy, high incidence of cancer and increasing awareness for the use of stem cells. Europe is also contributing second largest major share in the global market of Genetic Engineering. Asia-Pacific region is also anticipated to exhibit higher growth rate / CAGR over the over the coming years due to presence of developing countries, companies grabbing these opportunities and extracting their presence in the region. The Middle East and Africa holds the least share in global genetic engineering market owing to limited availability of medicine facilities.

The major market player included in this report are:

Thermo Fisher Scientific Inc.

Merck KGAA

Horizon Discovery Group Plc

Transposagen Biopharmaceuticals Inc.

New England Biolabs

Genscript Biotech Corporation

Lonza Group Ltd.

Origene Technologies Inc.

Integrated DNA Technologies Inc.

Amgen Inc.

The objective of the study is to define market sizes of different segments & countries in recent years and to forecast the values to the coming eight years. The report is designed to incorporate both qualitative and quantitative aspects of the industry within each of the regions and countries involved in the study. Furthermore, the report also caters the detailed information about the crucial aspects such as driving factors & challenges which will define the future growth of the market. Additionally, the report shall also incorporate available opportunities in micro markets for stakeholders to invest along with the detailed analysis of competitive landscape and product offerings of key players. The detailed segments and sub-segment of the market are explained below:

By Devices:

oPCR

oGene Gun

oGel Assemblies

oOthers

By Techniques:

oArtificial Selection

oGene Splicing

oCloning

oOthers

By End-User:

oResearch Institutes

oAcademic Institutes

oPharmaceutical Industries

oOthers

By Application:

oAgriculture

oMedical Industry

oForensic Science

oOthers

By Regions:

oNorth America

oU.S.

oCanada

oEurope

oUK

oGermany

oAsia Pacific

oChina

oIndia

oJapan

oLatin America

oBrazil

oMexico

oRest of the World

Furthermore, years considered for the study are as follows:

Historical year 2015, 2016

Base year 2017

Forecast period 2018 to 2025

Target Audience of the Global Genetic Engineering Market in Market Study:

oKey Consulting Companies & Advisors

oLarge, medium-sized, and small enterprises

oVenture capitalists

oValue-Added Resellers (VARs)

oThird-party knowledge providers

oInvestment bankers

oInvestors

Have Any Query Or Specific Requirement?Ask Our Industry Experts!

Table of Contents:

Study Coverage:It includes study objectives, years considered for the research study, growth rate and Genetic Engineering market size of type and application segments, key manufacturers covered, product scope, and highlights of segmental analysis.

Executive Summary:In this section, the report focuses on analysis of macroscopic indicators, market issues, drivers, and trends, competitive landscape, CAGR of the global Genetic Engineering market, and global production. Under the global production chapter, the authors of the report have included market pricing and trends, global capacity, global production, and global revenue forecasts.

Genetic Engineering Market Size by Manufacturer: Here, the report concentrates on revenue and production shares of manufacturers for all the years of the forecast period. It also focuses on price by manufacturer and expansion plans and mergers and acquisitions of companies.

Production by Region:It shows how the revenue and production in the global market are distributed among different regions. Each regional market is extensively studied here on the basis of import and export, key players, revenue, and production.

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Genetic Engineering Market Growing Rapidly with Significant CAGR, Leading Players, Innovative Trends and Expected Revenue by 2025 - Cole of Duty

Biotechnology processes streamlined in USMCA – Drgnews

When the original NAFTA agreement was implemented in 1994, biotechnology processes intended for practical agricultural use were in their early stages. But genetic modification has come a long way in the past quarter-century and advances continue daily.

Laboratory-based genetic sequencing and manipulation is clearly addressed in the new U.S.-Mexico-Canada trade agreement rules. Scientific processes and regulations that evolved independently for more than 25 years, now need to be standardized for the three countries.

Ian Affleck is Vice-President of Biotechnology for Crop Life Canada. He says new regulations will require systemic changes because the American and the Canadian GMO development rules evolved differently.

With the USMCA coming into force, theres a biotechnology chapter thats supposed to help the two countries align their approaches. Most countries around the world, the US included, chose a Process-based approach. So, their first step would be to say, Did you use genetic engineering, and create a GMO? If so, we want to take a look. Canada took a different approach, to say It doesnt matter how you made it, its really about what you made. Is the Product you made so new that we to take a look, as a government, to ensure its safety. We just start from a different foot to get to those approvals.

Affleck says recent advances in Gene Editing technology are more subtle and small differences can make big problems for seed-breeders accessing new markets.

The advent of gene editing is a really new technology for plant breeders. It adds a new wrinkle into the equation. With GMOs usually the changes were always big. With gene editing its not so certain. It may be able to make a larger or drastic change, or it might be a smaller change. So, this is why we need this policy guidance of what is new, to make sure that as plant breeders are embarking on products, they know what it is they have to do, to meet their regulatory expectations.

Crop Life Canada is lobbying in favor of the U.S. processed-based approach because Affleck says they dont want Canadian farmers to miss out on American products.

The USDA-APHIS rules, if you were to boil them down its have you done something thats something that plant couldnt have done on its own, and if you did, youre going to need an assessment. If you didnt, you dont need an assessment. Thats a very rational way forward. If were not clear on our policies going forward, it could make launching US varieties in Canada a little more tricky.

Glyphosate-tolerance, BT-insecticide integration and trait-stacking have all made changes to crops and yield.

The rest is here:

Biotechnology processes streamlined in USMCA - Drgnews

Global Genome Editing Market 2019 | How The Industry Will Witness Substantial Growth In The Upcoming Years | Exclusive Report By Market Research…

Gene editing technologies have an impact across multiple applications areas including plant and animal genetic engineering. However, the area of most disruption is across human cell line engineering, which enables the development of next generations therapies and drugs. However, the agricultural industry has seen more success with gene editing techniques largely due to the less stringent regulatory environment.

You will get latest updated report as per the COVID-19 Impact on this industry. Our updated reports will now feature detailed analysis that will help you make critical decisions.

Browse Full Report: https://www.marketresearchengine.com/upcommingreport/global-genome-editing-market-analysis-by-application-technology-and-end-userforecast-2015-to-2021

This market research report categorizes the genome editing market into the following segments:

The Genome Editing Market is segmented on the lines of Technology, Application, End User and Geographical Region. By Technology this market is segmented on the basis of CRISPR/CAS9, TALENs, ZFNs, Antisense Technology and Other Technologies. By Application this market is segmented on the basis of Cell Line Engineering, Animal Genetic Engineering, Plant Genetic Engineering and Other Applications.

By End User this market is segmented on the basis of Biotechnology and Pharmaceutical Companies sector, Government and Academic Research Institutes sector and Other Research Organizations sectors. By Geographical Region this market is segmented on the basis of North America, Europe, Asia and Rest of the World.

Recent developments across genome editing technologies have resulted in the creation of next generation nucleases that have higher levels of accuracy when correcting genetic mutations and defects. The classes under the genome editing technologies are the 4 broad families of nucleases: ZFNs, TALENs, CRISPR/Cas9, and Mega nucleases.

Global Genome Editing Market is expected to exceed more than US$ 7.5 billion by 2024 at CAGR of 14% in the given forecast period.

The global genome editing market is rapidly increasing due to the increased government funding for genomics technology, rise in the production of genetically modified crops and technological advancements these all factors are driving the growth of this market.

By End User this market is segmented on the basis of Biotechnology and Pharmaceutical Companies sector, Government and Academic Research Institutes sector and Other Research Organizations sectors. By Geographical Region this market is segmented on the basis of North America, Europe, Asia and Rest of the World.

Request Sample Report: https://www.marketresearchengine.com/upcommingreport/global-genome-editing-market-analysis-by-application-technology-and-end-userforecast-2015-to-2021

Table of Contents

1 INTRODUCTION

2 Research Methodology

3 Executive Summary

4 Premium Insights

5 Market Overview

6 Global Genome Editing/Engineering Market, By Technology

7 Global Genome Editing/Genome Engineering Market, By Application

8 Global Genome Editing/Engineering Market, By End User

8.1 Introduction8.2 Biotechnology & Pharmaceutical Companies8.3 Academic & Government Research Institutes8.4 Contract Research Organizations

9 Genome Editing/Genome Engineering Market, By Region

10 Competitive Landscape

11 Company Profiles

11.1 Thermo Fisher Scientific, Inc.

11.2 Merck KGaA

11.3 Horizon Discovery Group PLC

11.4 Genscript USA Inc.

11.5 Sangamo Biosciences, Inc.

11.6 Integrated DNA Technologies, Inc.

11.7 Lonza Group Ltd.

11.8 New England Biolabs, Inc.

11.9 Origene Technologies, Inc.

11.10 Transposagen Biopharmaceuticals, Inc.

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Global Genome Editing Market 2019 | How The Industry Will Witness Substantial Growth In The Upcoming Years | Exclusive Report By Market Research...

For The First Time, Scientists Find a Way to Make Targeted Edits to Mitochondrial DNA – ScienceAlert

Most cells in your body come with two genetic libraries; one in the nucleus, and the other inside structures called mitochondria - also known as the 'powerhouses of the cell'.

Until now, we've only had a way to make changes to one.

A combined effort by several research teams in the US has led to a process that could one day allow us to modify the instructions making up the cell's 'other' genome, and potentially treat a range of conditions that affect how we power our bodies.

The molecular foundation of this revolutionary gene editing tool is a toxin called DddA, secreted by the bacterium Burkholderia cenocepacia to sabotage other microbes when competition over resources turns serious.

Researchers from the University of Washington have had an interest in the toxin's talents for a while, finding it converts a nucleic acid base called cytosine into a different one commonly found in RNA, called uracil.

It's far from the first time researchers have looked to bacterial weapons for clues on how to tweak DNA in this way. In fact, a whole family of so-called deaminase enzymes had already been put to use in genetic engineering.

Unfortunately deaminase enzymes tend to only perform their code-swapping trick on single strands of DNA.

To get around this, another research team from the Broad Institute of MIT and Harvard combined their code-swapping deaminase with CRISPR technology, which entails using an RNA template to identify the sequence and then using enzymes to unzip the strands and make changes.

That isn't too much of a problem when you want to make edits to double strands of DNA inside something as welcoming as a cell's nucleus. But smuggling the RNA templates through the more selective membrane of a mitochondrion isn't quite so simple.

That's becausemore than a billion years ago, mitochondria were organisms in their own right, and over time they evolved to share responsibilities with the cells they now occupy, being delegated the business of breaking down glucose for power.

While many mitochondrial genes have long since been filed away in the host's nucleus, these tiny power units have held onto a few important sequences, which are tightly locked away behind a veil of membranes that don't take kindly to stray bits of RNA wafting through.

Fortunately, DddA had a unique talent for making changes to both DNA strands, opening the way to ditching CRISPR and its bulky RNA template in favour of alternative methods for targeting the sequence you want to change.

That third piece of the puzzle came in the form of an old school genetic engineering tool called a transcription activator-like effector, or TALE.

This class of enzyme can be tailored to find specific nucleic acid codes and break them apart. Just the thing for guiding a cytosine-swapping toxin into place.

Teamed up with DddA, a specially crafted TALE enzyme can find a target sequence inside mitochondria and turn any cytosine it finds into a uracil, which will later transform into a similar DNA-specific base called thymine.

In testing, this change occurred roughly half of the time.

A fifty-fifty change might not seem like a big win, but given there were no signs of potentially disastrous changes outside of target sequences, it makes for a promising precision engineering tool.

What's more, given there's no other contenders for editing mitochondrial genes, it's a landmark achievement with even this success rate.

Just as mutations in nuclear DNA can give rise to a wide variety of health conditions, mutations in the mitochondria's genes can also be problematic, affecting anything from brain development to muscle growth, energy levels, metabolism, and immunity.

Usually (though not always) passed through the eggs down from mothers, mitochondria and any damaging mutations can be inherited through the generations. Right now the best we might be able to do is combine cells from two different mothers to remove affected mitochondria.

But with this new DddA technology, we might finally be able to create animal models that mimic a range of debilitating mitochondrial conditions in humans. And, maybe one day, even fix them inside our own bodies.

This research was published in Nature.

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For The First Time, Scientists Find a Way to Make Targeted Edits to Mitochondrial DNA - ScienceAlert

Global Bioherbicides Market Witnessing a Consistency in Growth over the Past Few Years – GlobeNewswire

Covina, CA, July 15, 2020 (GLOBE NEWSWIRE) -- The report"Global Bioherbicides Market, By Mode of Application (Seed Treatment, Soil Application, Foliar, and Post-Harvest), By Source (Microbial, Biochemical, and Others (Plant Phytotoxic Residues and Other Botanical Extracts)), By Formulation (Granular, Liquid, and Others (Pellets, Dust, and Powder Form)), By Application (Agricultural Crops, Cereals & Grains, Oilseeds & Pulses, Fruits & Vegetables, Non-Agricultural Crops, Turf & Ornamentals, and Plantation Crops), and By Region (North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa) - Trends, Analysis and Forecast till 2029.

Key Highlights:

Request Sample PDF of this Business Report @https://www.prophecymarketinsights.com/market_insight/Insight/request-sample/4406

Analyst View:

Growing demand for organic products

Rise in the number of health conscious individuals, growth in environmental concerns, and government support provided by the respective through subsidies and premium market factors are growing demand for organic products in the market. This creates an opportunities to farmers across the globe to produce crops using organic methods, which further boost the global bioherbicides market. Furthermore, the bioherbicides market for organic products is rising at a significant rate due to growing consumer interest. There has been a substantial change in the preferences and eating habits of people, worldwide. The organic food products industry is also projected to benefit from financial aids, subsidies, and R&D programs conducted by different government and non-government organizations- APEDA (Agricultural & Processed Food Products Export Development Authority) (India), FiBL (Switzerland), and the United States Department of Agriculture (USDA) (US)-to help traditional farmers shift to organic farming. Thus, growth in the organic food market is triggering the demand for bioherbicides, coupled with organic manures.

Advances in genetic engineering

Bioherbicide finds application in the industries of leisure and crop control chemicals. For example, bioherbicide are useful to treat golf course as well as other grass types. Alternaria Eichhorniae are utilized to control growth of water hyacinth and Phytophthora plamivora help in controlling milk weed units in citrus orchards. Thus, advances in genetic engineering creates a major opportunity for the bioherbicide market as the new generation bioherbicide will be more effective against weeds.

Browse 60 market data tables* and 35figures* through 140 slides and in-depth TOC on Global Bioherbicides Market, By Mode of Application (Seed Treatment, Soil Application, Foliar, and Post-Harvest), By Source (Microbial, Biochemical, and Others (Plant Phytotoxic Residues and Other Botanical Extracts)), By Formulation (Granular, Liquid, and Others (Pellets, Dust, and Powder Form)), By Application (Agricultural Crops, Cereals & Grains, Oilseeds & Pulses, Fruits & Vegetables, Non-Agricultural Crops, Turf & Ornamentals, and Plantation Crops), and By Region (North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa) - Trends, Analysis and Forecast till 2029

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Key Market Insights from the report:

The global bioherbicides market accounted for US$ 1.7 billion in 2020 and is estimated to be US$ 6.3 billion by 2029 and is anticipated to register a CAGR of 15.7%. The market report has been segmented on the basis of mode of application, source, formulation, application, and region.

To know the upcoming trends and insights prevalent in this market, click the link below:

https://www.prophecymarketinsights.com/market_insight/Global-Bioherbicides-Market-4406

Competitive Landscape:

The prominent player operating in the global bioherbicides market includes Marrone Bio Innovations, Inc., Emery Oleochemicals, Deer Creek Holdings, Ecopesticides International, Inc., Special Biochem Pvt. Ltd., Verdesian Life Sciences, Bioherbicides Australia, HerbaNatur, Inc., and Engage Agro.

The market provides detailed information regarding the industrial base, productivity, strengths, manufacturers, and recent trends which will help companies enlarge the businesses and promote financial growth. Furthermore, the report exhibits dynamic factors including segments, sub-segments, regional marketplaces, competition, dominant key players, and market forecasts. In addition, the market includes recent collaborations, mergers, acquisitions, and partnerships along with regulatory frameworks across different regions impacting the market trajectory. Recent technological advances and innovations influencing the global market are included in the report.

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Global Bioherbicides Market Witnessing a Consistency in Growth over the Past Few Years - GlobeNewswire

Brave New World Arrives in the Future It Predicted – The New York Times

Ready for a thought experiment?

Imagine a society that has solved the problems of overpopulation and environmental collapse. Crime is a nonissue, as are homelessness and hunger. Racism? Sexism? Homophobia? Sorted. Science has conquered disease and disability. Everyone has useful work, perfect skin, total emotional equilibrium. Every day is a pleasure. Every night is a party.

Pop quiz: Is this a paradise? Or a prison?

Answer: Its the social science backdrop for Brave New World, the flagship drama from Peacock, NBCs streaming service. All nine episodes are available on Wednesday. Based on Aldous Huxleys alarmingly prescient 1932 novel of free love and social control, its a dystopia dressed up as a utopia. Or vice versa.

It seems perfect, said Jessica Brown Findlay, who plays the geneticist Lenina Crowne. But the minute you scratch the surface, you start to discover stuff.

But yeah, a couple of days there? she added. That would be great.

Prestige television likes its glimpses of the future and those futures usually skew dark: Westworld, Black Mirror, The Handmaids Tale. But Brave New World, which most viewers will remember vaguely if at all from some high school or college syllabus, presents a more ambivalent prospect and particular challenges.

Heres one: How do you take a nearly 90-year-old novel, a literary crystal ball so dead-on that many of its predictions (chemical birth control, mood stabilizers, genetic engineering) have already come true, and still make it feel like the future?

A collaboration between Universal Content Productions, which acquired the rights to the novel, and Amblin Entertainment, brought on for their world-building chops, Brave New World began at Syfy, then moved to USA, before landing at Peacock, shedding story and concept and the occasional writer along the way.

What often happens when you have big IP, you keep swinging until you get it right, said Dawn Olmstead, the president of Universal Content Productions.

The showrunner David Wiener (Homecoming, Fear the Walking Dead) apparently had the solution, situating the social theory within a love triangle. The theory part he explained this way: Huxley, he said, was very afraid of a world in which people would become so sexually stimulated, so pharmacologically numb and so distracted by entertainment and media, that they would fail to look within and beyond themselves in uncomfortable ways. So the future is now?

As for the love triangle: Lenina, a scientist inclined to zip-up minidresses, lives in New London, a city-state that has eliminated all social ills. Family, privacy and social mobility have been jettisoned, too. When uncomfortable feelings arise, citizens pop soma think psychoactive Skittles and drug them away.

Eager for a holiday, Lenina accompanies Bernard Marx (Harry Lloyd), an administrator with a thing for turtlenecks, on a pleasure tour of the Savage Lands. A living history park for the upper classes, the Savage Lands offer playlets based on antiquated customs marriage, consumerism. Did I mention that everyone in New London speaks in clipped British accents while the Savage Lands dialect is strictly American?

When the holiday goes wrong the Savage Lands has a sedition issue Bernard and Lenina escape with the help of a sweaty, stubbly John (Alden Ehrenreich) and his raspy, bottle-blond mom (Demi Moore). John returns with them to New London and he, Lenina and Bernard, each of them grasping for greater human connection, form the basic geometry. (No prize for guessing who she chooses, but heres a hint: His genes still encode body hair.)

To envision New London and the Savage Lands and optical interfaces between (in New London, everyone plugs into the internet via biomorphic contact lenses), the show hired the production designer David Lee (Watchmen). Huxleys world, I mean, its a design opportunity beyond belief, Lee said.

He and his team wanted to avoid the look of other films and series, though they did reference Blade Runner for its scale, he said, and Gattaca for its sleek modernism. Mostly, Lee looked to Brutalism Oscar Niemeyers Braslia, Carlo Scarpas elegant interiors, Soviet monuments that stretch heavenward.

Built of gently curved concrete, which can glow warm or cool depending on the lighting, New Londons buildings look both seductive and unyielding, as though Le Corbusiers studio had taken on a commission for a high-end spa (in a good way). The visual references for the Savage Lands: trailer parks and decayed Walmarts.

Theres plenty of C.G.I. involved, though less than you might think. The Savage Lands were shot in Dungeness, England. Lee cheerfully described the found location as a flat, barren wasteland that needed only set dressing. At Dragon Studios, just outside Cardiff, Wales, construction outgrew the buildings and spilled into the backlot and then into another studio, totaling 38 distinct sets and hundreds of thousands of square feet. Brown Findlay remembered stepping into Dragon Studios for the first time and finding this great big concrete church almost, she said.

The costumes, at least a thousand of them, also split the difference between modernism and futurism. Huxley had an obsession with zippers, and the costume designer Susie Coulthard honored it. But she embedded those zippers in vanguard materials, partnering with the Swiss textile innovators Jakob Schlaepfer on fabrics that have an oily or glassine appearance. A few outfits are made of balloon latex.

I felt so immersed in what I was doing by what I was wearing, Brown Findlay, a veteran of period shows like Downton Abbey and Harlots said. Thats saying something when youve worn a lot of huge giant corseted dresses.

Huxleys technology needed updates even beyond textiles, mostly because a lot of what he imagined (videoconferencing, television, test-tube babies) has already come to pass. Even his self-driving aircraft are in the works.

The novels utopian vision, with its ugly flares of racism and misogyny, also required renovation. The books hugely problematic, Wiener said. So the show pivoted toward equality, race-bending and gender-flipping several of the supporting characters.

It turns out theres nothing about those characters that necessarily needed to be white or male, Wiener said.

The main characters have undergone some changes, too. Lenina, a cheerful sex bunny in the book, has been granted interiority. Pompous Bernard has softened. In the novel, John is prissy and deeply neurotic, anti-sex and anti-fun.

Itd be a little like taking Mike Pence to New London, Wiener quipped. No one would want to watch that.

So Ehrenreichs John has loosened up and muscled up, though he remains extremely emo. Ehrenreich, best known as the titular swashbuckler in Solo, prefers to describe John as romantic.

The only thing he has to hold onto in is his ardent belief in a deep, emotional love, he said.

If the novel traffics mostly in satire, the tone here is more ambivalent. It gets to have its promiscuity what is prestige TV, after all, without the occasional orgy? and moralize about it, too.

Maybe you will share that ambivalence. After all, a society organized around pleasure consequence-free sex, party drugs, renewable fashion doesnt sound terrible. There were definitely moments on set where we were like, this is pretty good, Ehrenreich said.

But possibly thats just the prop soma talking. One of the novels spikier and more resonant points is that entertainment is its own drug, numbing us against discomfort. Thats something that we definitely recognize today, Lloyd, who plays Bernard, said. The moment where you sit on your own in the darkness to question what its all about, theres so many things to do on your phone.

Brave New World available soon on the Peacock app! is one more of them. Yes, it traffics in philosophy and muses upon the relationship between happiness and freedom, and what youre willing to risk of each for the other, Lloyd said.

But as Olmstead, the Universal Content president, told me twice the show shouldnt feel like homework. How much thinking will you do while you watch the buildings, the clothes, the toned bodies, the glowing skin? How well do sex and social critique actually mix? Well enough for more seasons, Wiener hopes.

Huxley didnt foresee this exact moment. (Very few of us had both a global pandemic and an overdue racial reckoning on our 2020 bingo card.) But the idea of a computer in every pocket, a social media feed for every mood, entertainment on demand and life as livestream wouldnt have surprised him.

Perhaps he can even imagine us now, pulling up Peacock, clicking on one Brave New World episode and then another. Bingeing while the world burns.

Continued here:

Brave New World Arrives in the Future It Predicted - The New York Times

Brain Benefits of Exercise Can Be Gained with a Single Protein – UCSF News Services

A little-studied liver protein may be responsible for the well-known benefits of exercise on the aging brain, according to a new study in mice by scientists in the UC San Francisco Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research.

The findings could lead to new therapies to confer the neuroprotective effects of physical activity on people who are unable to exercise due to physical limitations.

Exercise is one of the best-studied and most powerful ways of protecting the brain from age-related cognitive decline and has been shown to improve cognition in individuals at risk of neurodegenerative disease such as Alzheimers disease and frontotemporal dementia even those with rare gene variants that inevitably lead to dementia.

But many older adults are not able to exercise regularly due to physical limitations or disabilities, and researchers have long searched for therapies that could confer some of the same neurological benefits in people with low physical activity levels.

The new study, published July 9, 2020, in Science, showed that after mice exercise, their livers secrete a protein called Gpld1 into the blood. Levels of this protein in the blood correspond to improved cognitive function in aged mice, and a collaboration with the UCSF Memory and Aging Center found that the enzyme is also elevated in the blood of elderly humans who exercise regularly. But the researchers showed that simply increasing the amount of Gpld1 produced by the mouse liver could confer many of the same brain benefits as regular exercise.

If there were a drug that produced the same brain benefits as exercise, everyone would be taking it. Now our study suggests that at least some of these benefits might one day be available in pill form, said study senior author Saul Villeda, PhD, a UCSF assistant professor in the departments of Anatomy and of Physical Therapy and Rehabilitation Science.

Villedas lab has previously shown that biological factors present in the blood of young mice can rejuvenate the aging mouse brain, and conversely, factors in the blood of older mice can bring on premature age-related cognitive decline in young mice.

These previous results led Villeda lab graduate student Alana Horowitz and postdoctoral researcher Xuelai Fan, PhD, to pursue blood-borne factors that might also confer the benefits of exercise, which is also known to rejuvenate the aging brain in a similar fashion to what was seen in the labs young blood experiments.

Horowitz and Fan took blood from aged mice who had exercised regularly for seven weeks and administered it to sedentary aged mice. They found that four weeks of this treatment produced dramatic improvements in learning and memory in the older mice, similar to what was seen in the mice who had exercised regularly. When they examined the animals brains, they found evidence of enhanced production of new neurons in the region known as the hippocampus, a well-documented proxy for the rejuvenating benefits of exercise.

To discover what specific biological factors in the blood might be behind these effects, Horowitz, Fan and colleagues measured the amounts of different soluble proteins in the blood of active versus sedentary mice. They identified 30 candidate proteins, 19 of which, to their surprise, were predominantly derived from the liver and many of which had previously been linked to functions in controlling the bodys metabolism. Two of these proteins Gpld1 and Pon1 stood out as particularly important for metabolic processes, and the researchers chose to study Gpld1 in more detail because few previous studies had investigated its function.

We figured that if the protein had already been investigated thoroughly, someone would have stumbled upon this effect, Villeda said. I like to say if youre going to take a risk by exploring something new, you might as well go big!

The team found that Gpld1 increases in the blood circulation of mice following exercise, and that Gpld1 levels correlate closely with improvements in the animals cognitive performance. Analysis of human data collected as part of the UCSF Memory and Aging Centers Hillblom Aging Network study showed that Gpld1 is also elevated in the blood of healthy, active elderly adults compared to less active elders.

If there were a drug that produced the same brain benefits as exercise, everyone would be taking it. Now our study suggests that at least some of these benefits might one day be available in pill form.

Saul Villeda, PhD

To test whether Gpld1 itself could drive the observed benefits of exercise, the researchers used genetic engineering to coax the livers of aged mice to overproduce Gpld1, then measured the animals performance in multiple tests that measure various aspects of cognition and memory. To their amazement, three weeks of the treatment produced effects similar to six weeks of regular exercise, paired with dramatic increases in new neuron growth in the hippocampus.

To be honest, I didnt expect to succeed in finding a single molecule that could account for so much of the benefits of exercise on the brain. It seemed more likely that exercise would exert many small, subtle effects that add up to a large benefit, but which would be hard to isolate. Villeda said. When I saw these data, I was completely floored.

Through this protein, the liver is responding to physical activity and telling the old brain to get young, Villeda added. This is a remarkable example of liver-to-brain communication that, to the best of our knowledge, no one knew existed. It makes me wonder what else we have been missing in neuroscience by largely ignoring the dramatic effects other organs might have on the brain, and vice versa.

Further laboratory experiments have shown that Gpld1 produced by the liver does not pass through the so-called blood-brain barrier, which protects the brain from toxic or infectious agents in the blood. Instead, the protein appears to exert its effects on the brain via pathways that reduce inflammation and blood coagulation throughout the body. Both blood coagulation and inflammation are known to be elevated with age and have been linked to dementia and age-related cognitive decline.

The lab is now working to better understand precisely how Gpld1 interacts with other biochemical signaling systems to produce its brain-boosting effects, in hopes of identifying specific targets for therapeutics that could one day confer many of the protective benefits of exercise for the aging brain.

Authors: Additional authors on the study were Gregor Bieri, Lucas Smith, Cesar Sanchez-Diaz, Adam Schroer, and Geraldine Gontier of the UCSF Department of Anatomy; Kaitlin Casaletto and Joel Kramer of the UCSF Memory and Aging Center; and Katherine E. Williams of the UCSF Sandler-Moore Mass Spectrometry Core Facility.

Funding: The research was funded by Hillblom Foundation predoctoral and postdoctoral fellowships, Irene Diamond AFAR postdoctoral fellowship, the National Institutes of Health (NIH) National Institute on Aging (NIA) (AG064823, AG058752, AG023501, AG053382, AG055797), and a gift from Marc and Lynne Benioff.

Disclosures: The authors declare no conflict of interest. Horowitz, Fan, and Villeda are named as inventors on a patent application arising from this work.

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Brain Benefits of Exercise Can Be Gained with a Single Protein - UCSF News Services

Interleukin-11 (IL-11) Market Size By Product Analysis, Application, End-Users, Regional Outlook, Competitive Strategies And Forecast Up To 2026 – 3rd…

New Jersey, United States,- Latest update on Interleukin-11 (IL-11) Market Analysis report published with extensive market research, Interleukin-11 (IL-11) Market growth analysis, and forecast by 2026. this report is highly predictive as it holds the overall market analysis of topmost companies into the Interleukin-11 (IL-11) industry. With the classified Interleukin-11 (IL-11) market research based on various growing regions, this report provides leading players portfolio along with sales, growth, market share, and so on.

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Ziopharm Oncology Announces Initiation of Phase 1 Trial Evaluating Rapid Personalized Manufacturing CAR-T Technology in Patients with Relapsed CD19+…

BOSTON, July 09, 2020 (GLOBE NEWSWIRE) -- Ziopharm Oncology, Inc. (Ziopharm or the Company) (Nasdaq:ZIOP), today announced the initiation of a phase 1 clinical trial to evaluate CD19-specific CAR-T, using its Rapid Personalized Manufacturing (RPM) technology, as an investigational treatment for patients with relapsed CD19+ leukemias and lymphomas. The trial is now open for enrollment at The University of Texas MD Anderson Cancer Center.

In this trial, the Company utilizes its non-viral Sleeping Beauty genetic engineering technology to infuse CAR-T the day after electroporation. Ziopharms RPM CD19-specific CAR-T therapy results from the stable, non-viral insertion of DNA into the genome of resting T cells to co-express the chimeric antigen receptor (CAR), membrane-bound IL-15 (mbIL15) and a safety switch.

We are pleased to expand the scope of our clinical development with MD Anderson, as we seek to evaluate our RPM technology using CD19-specific CAR-T cells, said Laurence Cooper, M.D., Ph.D., Chief Executive Officer of Ziopharm. RPM is a promising manufacturing solution, as T cells from the bloodstream are genetically reprogramed with DNA plasmids from the Sleeping Beauty system and then simply administered the next day.

Our CAR-T therapy can be administered at low cell doses, which may control cytokine release syndrome and is appealing for the treatment of patients including those with CD19-expressing malignancies that have relapsed after allogeneic bone marrow transplantation (BMT). There are limited effective treatment options for such patients as evidenced by the low rate of remission and poor long-term survival, Dr. Cooper added.

Up to 24 patients with advanced CD19+ leukemias and lymphomas who have relapsed after allogeneic BMT will be enrolled in this investigator-initiated trial (NCT03579888). The primary endpoint of the study is to determine the safety and maximum tolerated dose of donor-derived genetically modified CD19-specific T cells manufactured using the RPM process. An additional study is planned through Ziopharms joint venture with Eden BioCell to evaluate the RPM technology using patient-derived (autologous) CD19-specific CAR-T in Greater China.

Research reveals three-year survival for adults with CD19+ acute lymphoblastic leukemia after allogeneic BMT ranges from 30% to 65%.1 For patients with other CD19+ cancers, allogeneic BMT can provide three-year survival rates between 30% to 75%.1 Few patients experience a durable remission following allogeneic BMT, regardless of the treatment modality, with some having a median survival of only 2 to 3 months.2

About Ziopharm Oncology, Inc.Ziopharm is developing non-viral and cytokine-driven cell and gene therapies that weaponize the bodys immune system to treat the millions of people globally diagnosed with a solid tumor each year. With its multiplatform approach, Ziopharm is at the forefront of immuno-oncology with a goal to treat any type of solid tumor. Ziopharms pipeline is built for commercially scalable, cost effective T-cell receptor T-cell therapies based on its non-viral Sleeping Beauty gene transfer platform, a precisely controlled IL-12 gene therapy, and rapidly manufactured Sleeping Beauty-enabled CD19-specific CAR-T program. The Company has clinical and strategic collaborations with the National Cancer Institute, The University of Texas MD Anderson Cancer Center and Regeneron Pharmaceuticals. For more information, please visit http://www.ziopharm.com.

Forward-Looking Statements DisclaimerThis press release contains forward-looking statements as defined in the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements are statements that are not historical facts, and in some cases can be identified by terms such as "may," "will," "could," "expects," "plans," "anticipates," and "believes." These statements include, but are not limited to, statements regarding the progress, design and timing of the Company's research and development programs, the potential benefits of the Companys therapies, and the Companys expectations regarding the number of patients in its clinical trials. Although Ziopharms management team believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks and uncertainties, many of which are difficult to predict and generally beyond the control of Ziopharm, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. These risks and uncertainties include among other things, changes in our operating plans that may impact our cash expenditures, the uncertainties inherent in research and development, future clinical data and analysis, including whether any of Ziopharms product candidates will advance further in the preclinical research or clinical trial process, including receiving clearance from the U.S. Food and Drug Administration or equivalent foreign regulatory agencies to conduct clinical trials and whether and when, if at all, they will receive final approval from the U.S. FDA or equivalent foreign regulatory agencies and for which indication; the strength and enforceability of Ziopharms intellectual property rights; competition from other pharmaceutical and biotechnology companies as well as risk factors discussed or identified in the public filings with the Securities and Exchange Commission made by Ziopharm, including those risks and uncertainties listed in Ziopharms Quarterly Report on Form 10-Q filed by Ziopharm with the Securities and Exchange Commission. We are providing this information as of the date of this press release, and Ziopharm does not undertake any obligation to update or revise the information contained in this press release whether as a result of new information, future events or any other reason.

Investor Relations Contacts:Ziopharm Oncology:Chris TaylorVP, Investor Relations and Corporate CommunicationsT: 617.502.1881E: ctaylor@ziopharm.com

LifeSci Advisors:Mike MoyerManaging DirectorT: 617.308.4306E: mmoyer@lifesciadvisors.com

Media Relations Contact:LifeSci Communications:Patrick BurseyT: 646.876.4932E: pbursey@lifescicomms.com

1 D'Souza A, Fretham C. Current Uses and Outcomes of Hematopoietic Cell Transplantation (HCT): CIBMTR Summary Slides, 2018. Available at https://www.cibmtr.org

2 Keil F, Prinz E, Kalhs P, et al. Treatment of leukemic relapse after allogeneic stem cell transplantation with cytotoreductive chemotherapy and/or immunotherapy or second transplants. Leukemia 2001; 15:355-361.

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Ziopharm Oncology Announces Initiation of Phase 1 Trial Evaluating Rapid Personalized Manufacturing CAR-T Technology in Patients with Relapsed CD19+...

Gulftimes : The case for Covid-19 antibody therapies – Gulf Times

By Michel Goldman and Michel D Kazatchkine/Brussels/Geneva

As many countries progressively relax their Covid-19 containment measures, preventing a renewed spread of the coronavirus from emerging infection clusters will be key to controlling the pandemic. And this will require the world to develop innovative new treatments.So far, policymakers have relied on non-pharmaceutical interventions such as testing, contact tracing, and quarantines to prevent a second wave of infections. Meanwhile, the search for Covid-19 therapies and prophylactic medicines has focused on products that could be immediately available, meaning existing drugs that were developed to treat other conditions. This approach has been largely unsuccessful, although a recent randomised clinical trial in the United Kingdom revealed that the dexamethasone corticosteroid reduced Covid-19 mortality in the most severe cases.Vaccines will of course be essential to overcoming Covid-19. But if and when they become available, it will still take many months to vaccinate enough people so that societies reach the level of collective immunity needed to halt the coronavirus. And the efficiency of any vaccine will likely vary depending on a persons genetic background, associated diseases, and age. Furthermore, vaccine access and coverage might be limited by production capabilities, economic considerations, and anti-vaccine sentiment among the population.That means we must also focus on developing new weapons that can directly target Sars-CoV-2, the virus that causes Covid-19. And, besides anti-viral chemical drugs, genetically engineered antibodies might be ideal for this purpose.Such antibodies are precisely tailored to neutralise the proteins that allow the Sars-CoV-2 virus to penetrate human cells. Moreover, they provide immediate immunity, which is critical not only to minimise organ damage but also to protect healthcare professionals and the infected persons contacts.The concept behind this type of immunotherapy was pioneered in France and Germany more than a century ago, when antibodies contained in the serum of immunised animals saved the lives of thousands of children during diphtheria epidemics. The same principle lies behind the current clinical trials using plasma from recovering Covid-19 patients. But because not all antibodies are protective indeed, some can even aggravate disease researchers are focusing on those known for their anti-viral activity.Contemporary genetic engineering can produce highly specific humanised antibodies. Although these biological agents are best known for revolutionising the treatment of cancer and autoimmune diseases, there is already evidence of their efficacy as anti-infectious agents.For example, the palivizumab antibody is used to prevent respiratory syncytial virus infections in infants, while other antibodies have been found to prevent or treat anthrax. And another has proven effective in helping HIV-infected people who are resistant to standard treatments. Most recently and relevantly, a cocktail of antibodies soon to be approved by the US Food and Drug Administration (FDA) was found to reduce Ebola mortality among patients.Regeneron Pharmaceuticals, the US biotechnology firm that produced the Ebola antibodies, is now using its proprietary technology to develop a cocktail of two Covid-19 antibodies that are currently being tested in human trials. On July 7, Regeneron Pharmaceuticals announced that it had received a $450mn contract to manufacture and supply the antibody cocktail as part of the Biomedical Advanced Research and Development Authoritys (BARDA) Operation Warp Speed. Several other companies are developing antibodies with the help of US government funding via the Accelerating Covid-19 Therapeutic Interventions and Vaccines partnership. This initiative involves BARDA, the National Institutes of Health, the FDA, and the US Department of Defense, together with major pharmaceutical firms and philanthropic organisations such as the Bill & Melinda Gates Foundation.Unfortunately, antibody therapies are currently receiving less attention in the European Commissions Coronavirus Global Response. This effort, which the Commission developed in collaboration with other governmental, corporate, and philanthropic organisations, aims to support the Access to Covid-19 Tools (ACT) Accelerator that the World Health Organisation and other global partners launched in April. But the Economist Intelligence Unit reports that the Covid-19 Therapeutics Accelerator, a co-convenor of the ACT initiative, had so far invested only $59mn, mostly in clinical trials exploring the potential benefits of repurposed drugs.Several challenges still need to be addressed before genetically engineered antibodies can join the fight against Covid-19. These include increasing the antibodies stability in vivo to optimise the number of doses required, and decreasing manufacturing costs in order to make the therapy economically viable.Funding organisations must now invest more resources to overcome these remaining hurdles. The rewards are potentially huge: antibody treatments that not only rapidly control viral replication in Covid-19 patients, but possibly also prevent vulnerable individuals from contracting the disease. Project SyndicateMichel Goldman, founder and co-director of the Institute for Interdisciplinary Innovation in Healthcare (I3h) and Professor of Immunology at the Universit Libre de Bruxelles, was Executive Director of the Innovative Medicines Initiative from 2009 to 2014.l Michel D. Kazatchkine, a senior fellow at the Graduate Institute of International and Development Studies in Geneva and a member of the Global Commission on Drug Policy, was Executive Director of the Global Fund to Fight Aids, Tuberculosis, and Malaria from 2007 to 2012.

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Gulftimes : The case for Covid-19 antibody therapies - Gulf Times

Sonu Sood to write book on helping migrants amid Covid-19 crisis – Deccan Herald

Actor Sonu Sood, who catapulted to the national spotlight for his work in helping migrants reach their homes amid the COVID-19 pandemic, will pen a book about his experience.

His debut book, as-of-yet untitled, will reveal the emotional and often challenging journeys the actor undertook along with the people he helped.

It will be released later this year, announced publishing house Penguin Random House India on Wednesday.

"... I want to thank God for making me a catalyst in helping the migrants. While my heart beats in Mumbai, after this movement I feel a part of me lives in the villages of UP, Bihar, Jharkhand, Assam, Uttarakhand and various other states where I have now found new friends and made deep connections.

"I have decided to put these experiences, stories that are embedded in my soul forever, in a book ... I'm excited, nervous and overwhelmed, and I can't wait to connect with you through my book. I look forward to your supportand love you all," Sood said in a statement.

The 46-year-old actor launched an initiative to help reunite migrant workers who were stranded in Mumbai with their families in distant corners of the country.

Sood and his team rolled out a toll-free number and a WhatsApp helpline to connect with the workers and then arrange transportation for those desperate to reach their homes. Later, he arranged for food, buses, trains and even chartered flights for stranded migrants, some of whom were walking home after the lockdown was imposed earlier in March and left them jobless.

"The past three-and-half months have been a kind of a life-changing experience for me, living with the migrants for sixteen to eighteen hours a day and sharing the pain. When I go to see them off as they begin their journey back home, my heart is filled with joy and relief.

"Seeing the smiles on their faces, the tears of happiness in their eyes has been the most special experience of my life, and I pledged that Ill keep on working to send them back to their homes until the last migrant reaches his village, to his loved ones," he added.

Famous antagonist in reel-life, and a true hero in real, Sood on Monday also pledged financial support to over 400 families of migrants, who died or were injured during the coronavirus lockdown.

Milee Ashwarya, publisher, Ebury Publishing and Vintage Publishing, Penguin Random House, said the book will bring together the story of Sood's amazing journey - "of people who were suddenly left without security and livelihood; of hope and the feeling of oneness that binds us all together".

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Sonu Sood to write book on helping migrants amid Covid-19 crisis - Deccan Herald

Wait for the migrant: Once opportunities are there, they will return – The Indian Express

Written by Yoginder K. Alagh | Updated: July 10, 2020 9:26:39 am Statements emphasising that in a downturn economy, local labour will fill the gap, simply ignore the cycles in the demand for labour. (Illustration by C R Sasikumar)

Migrants, very often, get an undeserved bad name in our market economy. However, in Indias not very old experience, and in the process of development generally, as migration plays a major developmental role its careless and somewhat irresponsible to downplay the role of migrant workers. Statements emphasising that in a downturn economy, local labour will fill the gap, simply ignore the cycles in the demand for labour. We in the cities, after all, will have to worry about our needs whenever the M or the W-shaped swing takes place.

In the Seventies of the last century, the economist K N Raj, a guru to many of us, brought the importance of migrant labour to our attention. Raj, an example to many of us, worked in India for most of his career. But at that time, certain compelling personal reasons led him to work with the UN. He chose to go to the ILO and set up the ILO ARTEP an Asian Regional Employment Programme. There Raj brought to our notice the historical role of migration in Japans development. He propagated the work of the eminent Japanese economist Kaoru Ishikawa. Ishikawa had shown that labour migrated to those Japanese prefectures which were growing fast economically, including agriculturally. Diagrammatically, if you plotted output per unit of land against labour per unit of land, you got an inverse relationship in a rectangular hyperbola. If agricultural productivity went up, more labour was sucked into the prefecture. Much like migrant workers from UP and Bihar going to the Green Revolution belt.

Raj wanted to test Ishikawas hypothesis in India. He asked me, G S Bhalla and Amit Bhaduri to do this job. He knew me because he was a great admirer of my patience in selecting younger people at the Centre for Development Studies in Thiruvananthapuram and holding my own against some of the bigwigs of the institute who tended to be very formal.

I had co-authored a book with Bhalla on district-level agricultural experience and had a lot of data. Over many rounds of analysis and discussions, Bhaduri kept on saying that this business was a truism. At one stage, a little fatigued, I had to tell him: We dont want to work with falsisms, do we? Lets go ahead. This was the origin of the, by now, well-known Alagh, Bhalla and Bhaduri thesis. Our paper proved that there was indeed a suction mechanism in Indian agriculture.

Opinion | There is an irrational preference for expensive Covid treatments over effective ones

Not satisfied, Raj organised a set of seminars on the issue in different parts of India. At Bengaluru, D T Lakdawala, the then deputy chairman of the Planning Commission chaired the meeting. D M Nanjundappa, chairman of the Karnataka State Planning Commission, said that if instead of irrigation pumps we had the old buffalo driven wheels and water was lifted by buckets, employment in well irrigation would be higher. Bhalla, a Marxist by inclination and very critical of what he thought were ante-diluvian ideas, responded that if we do irrigation with spoons, employment would be even higher. Nanjundappa protested that Bhalla is making fun of him. Lakdawala, the great liberal, doused the fire.

Later, the ILO economist of Pakistani origin, Rashid Amjad, published a book that talked about the similar experience of migrant workers in several other countries, making the Ishikawa hypothesis a universal theory endorsed by the ILO. Labour migration as a serious policy issue had arrived.

In this century, as the different globalisation crises hit us, Iwan J Azis, the Indonesian economist who held positions at the Cornell University in the US and the National University of Indonesia, and I looked at reverse migration. Azis showed that the Southeast Asian economies were chugging along at 6 per cent plus growth when the SARS outbreak hit the region. The Thai baht lost half its value in a few days. The contagion was a lot like the later viruses. In a few months, many countries lost upto a third of their wealth. India, I showed, fared better because it was a relatively closed economy.

Azis showed that there was reverse migration. The migrants went back to their villages where they did not have to starve. They had picked up skills in the cities which helped them initiate agro-based development like diversification away from rice in Indonesia. The experience was similar in Philippines and Vietnam. Migrants were regarded as an asset.

Opinion | The regimes of boundaries: They have multiplied, even as Covid nudges us towards broader discourse of access

At a dinner in Delhi, I was made to sit at the head table with the then Prime Minister Atal Bihari Vajpayee. I had written to him to get the meltdown in Surat looked into. He turned to me and said, Alagh saheb, sab theek hain (Everything is all right). I didnt have the heart to complain.

Migration has always been a shock absorber. It is this role we choked off by regional lockdowns and transportation blockages, causing enormous suffering and many deaths. I get disturbed when some very eminent colleagues recognise the uncertainty of the situation and yet choose livelihood over life. A filled up belly may starve. But the dead wont come back. This is not the empirical welfare economics my teachers many of them Nobel Prize winners taught me. Good economics doesnt make careless choices between life and death.

We have now, hopefully, learnt from our mistakes. Today, many of the migrants may say that they will never come back. But once opportunities are there, they will return. Until then, it is not quite kosher to stop them from going home under pressure from builder lobbies. The market should be allowed to work for both industry and labour.

In fact, the reverse migration could bolster the agricultural sector in the short-run. We should integrate the process of reverse migration with agro-based development in the short-run and wait for the migration back to cities as we get out of this disaster.

This article first appeared in the print edition on July 10, 2020 under the title Wait for the migrant. The writer, a former Union Minister, is an economist.

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Wait for the migrant: Once opportunities are there, they will return - The Indian Express

National Level Webinar Held On Rebuilding Livelihoods of Migrants – Pragativadi

Bhubaneswar: As a little more than a million Migrant Laborers have registered with the State Governments dedicated COVID -19 Website and a large number of them have returned back home triggered by uncertainty over Corona Pandemic, time to map their skills to redraw livelihood strategies for them. Government should plan out both long-term and short term strategies so that their livelihoods are secured thereby avoiding the risk of distress, human trafficking and re-migration through alternative pathways, said the outcome of a National Level Webinar, a Virtual Dialogue on Mainstreaming Migrant Workers. Migrants after losing jobs are facing unemployment and poverty back home as uncertainty looms large all over.

The webinar was organized jointly by City-based Focus Odisha Foundation and Mahashakti Foundation in collaboration with the National level Migrant Resources Centre Migration Watch India on July 13. About one hundred participants drawn from a cross-section of society and representatives of civil society organizations from across the country participated to deliberate on the most pressing issue of the time Migrant crisis.

While making a lead presentation Executive Director of Action Aid Association India and Co-Chair of World Urban Campaign of UN Habitat Sandeep Chachra underlined the need for rebuilding livelihoods strategies and ensuring social safety net for both for returned migrants and informal workers working elsewhere in the country, a huge community estimated at one-fourth of the total population of the country. Chachra further added that we need to think beyond MGNREGS and explore alternative skill-based livelihoods.

Dr Niranjan Sahoo, Sr Fellow at New Delhi based Indias leading think tank The Observer Research Foundation stressed the need for ensuring legitimate entitlements of migrant workers as there have been a large scale resentment across the country following the alleged denial of their rights as these communities facing identity crises as nowhere people.

its good that MGNREGS have provided fifty percent jobs to a huge population of jobless people during the last couple of months in rural hinterlands and have created 1.2 million man day in this period, but if we will not properly implement Pradhan Mantri Garib Kalyan Yojana, Food Security packages and a slew of programmes announced for migrants benefit, millions of people will be getting to poverty trap again, said Sahoo.

State head of UNDP Abha Mishra in her presentation highlighted the need for mapping the skills and knowledge of Migrant people so that we will be able to a draw a line between skilled and unskilled people and plan for the restoration of their livelihoods. She further added that there is a need to think about developing natural industries like livestock and diary development, focusing on nutrigardens, organic farming besides emphasizing on agricultural and Tourism development.

Shaonli Chakraborty of Bengaluru based nation-level forum Covid Action Collaborative called upon civil society actors, Industries, Governments to redirect their priorities for the resettlement and restoration of jobs of millions of migrant laborers; otherwise, we will lose sight of prospering societies. All it needed is to facilitate their social security and occupational safety both at Origin and Destination Places and at Transit points.

Mumbai based CSR Head of ACC Ltd Pratyush Panda questioned on how skill persons can be engaged in MGNREGS work which is largely for unskilled rural wage workers. As things stand today both Industries and civil society should come together to facilitate re-engagement of lakhs of skilled migrant workers.

Convenor of COVID-19-Civil Society Initiative and Migration Watch India Sudarshan Chhotoray while outlining the context described how Corona Pandemic has exposed vulnerability for a large section of the economically backward population. Time has come we need to recognize the Talents, Skills, and knowledge migrants have brought in and the key to unlocking their potential is to put a right based orderly system in place to reintegrate them in the local labour market thereby extending their access to social and economic security.

Prominent among the Guests who spoke were Sr Journalist and Foreign Affairs Expert Gopal Misra, Convenor of OIKTREE Initiatives William Stanley, President of ADHIKAR Ms N Amin, Joint Secretary of Utkal Samaj Madras Biswajit Kanungo and President of Mahashakti Foundation Santosh Kumar Mishra.

A special session was devoted on-How we reached out to thousands of standard Migrants? Where activists shared their experiences in dealing with the unfolding crisis and coordination they had with Government Authorities, Civil Society, Citizens Groups, Activists, Industries, and philanthropists across the Country.

CEO of Mahashakti Foundation Jugal Kishore Patnaik summed up the outcome and deliberations and Shrishita Rath proposed the vote of thanks.

Originally posted here:

National Level Webinar Held On Rebuilding Livelihoods of Migrants - Pragativadi