A Dead Star Gave Off Something Scientists Have Never Seen Before

In late April, the international team observed a massively bright outburst of X-rays and radio waves. They traced it back to a magnetar in the Milky Way.

An international team of astronomers say they observed a magnetar — the remains of a dead star with an extremely powerful magnetic field — unleash a burst of high-energy radiation made up of X-rays and radio waves that have never previously been observed.

It was likely a type of mysterious cosmic outburst referred to as fast radio burst (FRB), which have long puzzled astronomers. But thanks to a new study about the strange magnetar, published this week in the Astrophysical Journal Letters, that could be starting to change.

In late April, the international team spotted something entirely unprecedented: an FRB originating within the Milky Way, emanating from a magnetar called SGR 1935+2154, some 30,000 light-years away from Earth.

These outbursts tend to be so bright that they’re billions of times more luminous than the Sun — but only last for a split second.

The discovery was made possible by the “Burst Alert System” built into the European Space Agency’s INTEGRAL (International Gamma-Ray Astrophysics Laboratory) space telescope, which “automatically alerted observatories worldwide about the discovery in just seconds,” as Sandro Mereghetti, astrophysicist at the National Institute for Astrophysics in Milan, Italy, and lead author, explained in a statement.

FRB hunters at the Survey for Transient Astronomical Radio Emission 2 (STARE2) in the US were able to confirm the dazzling sight just hours later.

The observation could settle the major mystery surrounding FRBs: whether they do indeed originate from magnetars.

“We’ve never seen a burst of radio waves, resembling a Fast Radio Burst, from a magnetar before,” Mereghetiti sated. “This is the first ever observational connection between magnetars and Fast Radio Bursts.”

“It truly is a major discovery, and helps to bring the origin of these mysterious phenomena into focus,” he added.

READ MORE: Dead star emits never-before seen mix of radiation [European Space Agency]

More on the burst: Scientists Detect Powerful Radio Burst Coming From Our Own Galaxy

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A Dead Star Gave Off Something Scientists Have Never Seen Before

NASA Venus Rover Designed For “Exploring Hell”

NASA just unveiled the winners of its

Hellscape

NASA just unveiled the winner of its Venus rover design contest, dubbed the “Exploring Hell” challenge.

The submissions were surprisingly on-brand: Some had hellish names like “DEMoN Fire Sensor” and “SPIDER,” Popular Mechanics reports. But jokes aside, the name of the contest is a fair description of what these rovers would need to survive. No spacecraft has survived longer than 50 minutes on the Venus, which is the hottest planet in the solar system and is blanketed by sulfuric acid storm clouds.

First Place

As such, the first-place design looks more like a “BattleBots” contestant than a typical NASA rover. “Venus Feelers,” as it’s called, was designed by an Egyptian architect named Youssef Ghali. The robot is powered by a small, back-mounted windmill and has four “feeler” arms of tiny wheels that detect obstacles so the rover doesn’t get stuck as it trudges along.

An accompanying video shows how those tiny wheels can spot large rocks, deep pits, or cliff edges, which alerts the rover that it should find a different path.

Acid Rain

The rovers sport contraptions like giant mesh-covered wheels, bumpers, or long and spindly legs that could help them avoid obstacles on the surface of Venus. Surviving the planet’s acid rains may be a challenge for another day, but for now NASA is happy with the designs it received.

“The response from the community was incredible and better than I ever dreamed,” project manager Jonathan Sauder said in a press release.

READ MORE: This Machine Could Explore Hell for NASA [Popular Mechanics]

More on Venus: NASA Scientists Imagine Studying Venus From A Floating Research Colony

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DARPA Deploys Tiny Satellite That Could Take Best Pictures of Space Ever

DARPA recently deployed a tiny camera satellite that the agency hopes can take sharp images of exoplanets that are usually washed out of pictures.

Enhance!

A tiny military satellite may be able to take the sharpest pictures yet of extremely distant and difficult to spot objects out in space.

DARPA, the Pentagon’s research division, recently deployed what they call the Deformable Mirror (DeMi) CubeSat from the International Space Station, according to a press release. Over the next year, the toaster-sized satellite will use its camera to focus on the dim, distant objects in space that usually get washed out by nearby stars or other larger objects.

Spy Cam

DeMi is drastically smaller than famous space cameras like the Hubble Space Telescope, but DARPA is counting on its ability to focus on overlooked celestial bodies to vastly improve the images scientists can capture.

“Space telescopes currently in orbit are limited in ability to detect and distinguish small, dim objects next to large, bright objects — for example, dim exoplanets next to bright stars,” DeMI project manager Stacie Williams said in the press release. “Our goal is to demonstrate the benefits of a [microelectromechanical systems] deformable mirror to actively correct the images of distant objects in space.”

Field Test

The CubeSat camera will also be treated as a test to see how the extreme temperatures, radiation, and other harsh conditions of space impact the camera, which relies on several small moving parts.

For instance, the mirror uses over 140 different actuators to adjust its shape and line up a shot — so DARPA will be tracking how well it can adjust as pieces warp or fall out of alignment.

READ MORE: Miniature telescope demonstration focuses on sharpening view of distant objects in space [DARPA]

More on space cameras: NASA Says Hubble Observed a “Flapping Shadow” in Distant Space

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Deep Space Exploration and Technology Market to Grow at a Stayed CAGR from 2019 – GroundAlerts.com

The ' Deep Space Exploration and Technology market' research added by Market Study Report, LLC, is essentially an exhaustive review of present and future trends of this business sphere. The report also collates a concise outline of industry share contenders, market share, market size in terms of value and volume, distribution channel, and geographical spectrum along with revenue predictions of the industry landscape.

The Deep Space Exploration and Technology market report entails a comprehensive database on the future projections of the pivotal aspects of this industry vertical including market trends, current revenue, market size, and profit estimates. The research provides an outline of how the Deep Space Exploration and Technology market will perform by highlighting the key factors influencing the market dynamics and growth rate of the industry over the forecast period. Furthermore, challenges deterring the market growth as well as the growth opportunities across regional terrains are elucidated in the report. Additionally, the study encapsulates details pertaining to the impact of the COVID-19 pandemic on the market size.

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Addressing the Deep Space Exploration and Technology market with respect to the regional terrain

Deep Space Exploration and Technology Market categorization: North America, Europe, Asia-Pacific, Middle East & Africa and South America

An overview of the details highlighted in the report with respect to the regional markets:

A comprehensive understanding of the Deep Space Exploration and Technology market in terms of the product and application spectrums:

Product landscape:

Product types: Rockets, Landers, Robots, Satellites and Orbiters

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Application segmentation: Moon Exploration, Transportation, Orbital Infrastructure, Mars Exploration and Others

Specifics covered in the report:

Other inferences from the report:

A gist of competitive terrain of the Deep Space Exploration and Technology market:

Major participants: Airbus S.A.S, Northrop Grumman Corporation, Astrobotic, Bradford, Blue Origin, Axiom Space, MAXAR Technologies Inc., Lockheed Martin Corporation, Nanoracks LLC, Masten Space Systems, Planetary Resources, Thales Group, Space Exploration Technologies Corp. (SpaceX), The Boeing Company and Sierra Nevada Corporation

Key parameters that govern the competitive dynamics:

Significant Key Features Highlights of The Reports:

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China’s Mars mission is a glimpse into its space ambitions. But we’re not in a space race yet – ABC News

NASA is set to launch its fourth Mars rover mission today.

The mission includes a micro-helicopter that will attempt the first flight on the red planet.

But by the time it arrives around March next year, another rover from China will be preparing to touch down.

Both missions have prompted a great deal of speculation about a new 21st century space race.

Last time it was the world's two biggest superpowers, Russia and the United States, competing to send a man to the Moon.

But this time another major superpower has entered the mix.

Perseverance as the US rover is called is part of an ambitious long-term NASA program to capture ground samples and transport them back to earth, where they can be studied in unprecedented detail.

The mini-helicopter experiment aims to see whether it's possible to carry out close-range aerial surveys of Mars covering more ground than a rover could.

China's mission, on the other hand, is ambitious in other ways.

NASA, China and the United Arab Emirates are going to Mars. Here's a quick look at each of the missions.

The Tianwen-1 probe named after a classic poem titled 'heavenly questions' blasted off from China's southern island Hainan last week and seeks to narrow the technological gap with the US by decades.

China's military-led space program is aiming to achieve three 'firsts' a Mars orbiter, a lander and a rover all in one mission.

"China has now joined the Mars space club," Professor of Aerospace Engineering at Tsinghua University in Beijing, Fu Song, told the ABC.

"But China doesn't want to compete with the US the US has the most advanced technology."

The Tianwen-1 probe is the latest in a steady program of space missions helping China become a major space power.

In 2003, China became only the third nation to successfully carry out human spaceflight.

Since then it has launched two space laboratory modules, called Tiangong.

And in 2018, China became the only country to successfully land a probe on the far side of the moon.

The mission was a technologically difficult feat given communication signals with Earth have to be bounced off satellites.

The various missions aim to build towards China independently operating a manned space station in low orbit within a few years.

If successful, it may become the only space lab, with doubts over whether the International Space Station will be replaced once it is decommissioned later this decade.

China's lunar goals over the next decade also include the possible establishment of a science research post on the south pole of the moon.

The project will potentially be built using 3D printing technology, although public details are scarce.

"Success in today's mission forms the vital base for success in our next missions," deputy director of China's Space Administration Wu Yanhua told State TV after the Tianwen-1 launch.

"If the entire program is successful, it will be a major milestone for China."

Analysts say the rapid strides China's space scientists and engineers are making doesn't mean the dawn of a new space 'race'. At least, not yet, anyway.

Are you across the Red Planet or will our quiz leave you red-faced?

Instead, it suggests we are about to enter a new 'golden era' of space exploration.

Another entrant to Mars exploration the United Arab Emirates also recently launched an orbiting satellite with the technological help of the US.

Along with China, the mission marks a significant change in the global space field, which has so far been dominated by the US and Russia.

But landing on Mars remains the most difficult challenge.

Loading

And as such, according to Dean Cheng a China space and military analyst at US think tank The Heritage Foundation we are still some way off comparing China's space program to the US.

"What this does is it puts China on the map as only the third nation to send a probe to Mars," Mr Cheng told the ABC.

"But you are comparing apples and kumquats. This is a major moment for Chinese space science it's their first interplanetary probe going beyond the Earth's moon system.

"But we have to keep in mind the US was able to land probes on Mars back in the 1970s and along with the Russians had Martian orbiters before that."

Despite the recent successes of China's space missions, experts also warn the chances of pulling off all three goals of the Tianwen-1 mission will be difficult.

"Only NASA has managed to land safely on the Martian surface," said space journalist Andrew Jones, who is monitoring China's space program.

"The Europeans have failed, the Russians and Soviets have failed, everything has to go perfectly.

"For a first attempt, it's a tall order."

By contrast, Perseverance will be the fifth rover to land on Mars after missions in 1997, 2004 (which landed two rovers) and 2012.

The US banned cooperation with China on space in 2011 due to concerns China would gain access to American technologies and apply them to military use.

Beijing has long argued against the ban and has largely cooperated with Russia and Germany instead.

The US restriction highlights that despite its technological lead, competition in space will be a major area of rivalry in future.

One advantage China has is that its space program isn't subject to the whims of changing political administrations.

"At the moment, at least with the current administration, the US is aiming to go to the moon with astronauts this decade," Jones said.

"That's something which is way beyond the reach of Chinese capabilities."

The question is, for how long?

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China's Mars mission is a glimpse into its space ambitions. But we're not in a space race yet - ABC News

Turkey "freezes" Oil And Gas Research In The Eastern Mediterranean – GreekCityTimes.com

Turkish Presidential Spokesperson brahim Kaln said Turkey will suspend research for oil and gas exploration in the Eastern Mediterranean, pending talks with Greece.

In an interview on CNN Turk, Kalin said that President Recep Tayyip Erdoan told his aides to put this on hold for some time.

Last week, Turkey announced plans to dispatch research vessel Oruc Reis to the south and east of the Greek island of Kastellorizo.

Greece gave an extreme reaction after our Navtex as if we will go occupy Meis Island (Kastellorizo). Nevertheless, our president said since these negotiations are continuing, lets see what happens and put this on hold for some time, Kalin said.

The Greek Armed Forces were put on high alert on land, sea and air, and continue to closely monitor Turkish movements.

Everyone should continue working on their own continental shelves and conduct joint work in contested areas, Kalin continued. He also said that bilateral issues with Greece should be solved through dialogue rather than through threats on Turkeys bid for European Union membership.

Within the framework of our presidents orders, we are ready to speak about all bilateral issues with Greece without preconditions: the Aegean, continental shelves, islands, air space, exploration and the Eastern Mediterranean, Kalin added.

Greek government spokesman Stelios Petsas welcomed Turkeys decision.

This is a positive development, Petsas told Skai. We want to have open channels of communication with Turkey and to discuss the issue that has been plaguing the two sides for many decades now: The demarcation of maritime zones. This is the issue, which of course needs the proper framework to move forward.

On his part, Greek Foreign Minister Nikos Dendias said Ankaras decision to suspend research for oil and gas exploration in the Eastern Mediterranean will help de-escalate tensions between Greece and Turkey.

The statement of the presidential spokesman is a positive development for us. The Greek government has always said, and continues to say, that the necessary condition for dialogue is the de-escalation on the part of Turkey, he said after his meeting with Spanish counterpart Arancha Gonzalez Laya in Athens.

We believe that this is in the interest of both Turkey and Turkish society, he added.

However, a few hours after Turkey withdrew Oruc Reis, they issued a NAVTEX for its second seismic research vessel Barbaros for research in the Cypriot EEZ

The NAVTEX is valid from Tuesday, July 28, until September 20.

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Turkey "freezes" Oil And Gas Research In The Eastern Mediterranean - GreekCityTimes.com

Why NASA Is Headed Back to Mars with Mars Rover Perseverance – Smithsonian

Smithsonian Voices National Air and Space Museum

In the last 20+ years, NASA has launched multiple stationary landers and mobile rovers to the surface of Mars: the Pathfinder lander and Sojourner rover (1997), Spirit (2004), Opportunity rovers (2004), Phoenix lander (2007), and Curiosity rover (2012), and the InSight lander (2018). Through their exploration, we have learned so much about the Red Planet. Only Curiosity and InSight are still active, but since late 2012, there has been a new Mars rover mission on the horizon. The Mars 2020 rover Perseverance is scheduled to launch on July 30, 2020.

The rover's name respresents what it takes to achieve something like sending a robotic explorer to another planet.

"There has never been exploration without perseverance," NASA associate administrator Dr. Thomas Zurbuchen said about the name. "Perseverance and curiosity together is what exploration is all about."

Perseverance will soon be on its way to the Red Planet. NASA is targeting July 30, 2020, at 7:50 am for launch, with the landing on Mars occurring on February 18, 2021. Once on the surface of Mars, the rover will traverse the landscape for at least one Mars year (nearly two Earth years).

In the latest episode of our AirSpace podcast, our hosts talk about what excites them about this mission.

So whats new about this rover? Museum scientist John Grant, who was on the selection committee for the rover's landing site, shares what is special about the Perseverance rover:

Perseverance, which has six wheels and is about the same size as a small car, looks very much like the Mars Science Laboratory Curiosity. Curiosity is currently exploring Gale Crater and working on constraining the timing and duration of habitable conditions associated with a lake that existed more than 3 billion years ago. The Mars 2020 rover, however, has a different payload of science instruments and is not only focused on finding signs of ancient habitable conditions, but is also looking for evidence of past microbial life. It will also use a 2.1 meter long arm, which can bend and stretch much like a human arm and enables the rover to access rocks and soils, to select and cache samples that could potentially be returned to Earth by a future mission.

There are seven instruments on board the rover, collectively geared towards learning more about the geology, atmosphere, environmental conditions, and any potential biosignatures on Mars. These instruments are supplemented by cameras used by engineers for detecting hazards and planning drives. And for the first time, a robotic helicopter will be included that will test technology for scouting out high priority exploration targets and planning the rover traverse.

Perseverance will land in the Jezero crater in the northern hemisphere of Mars (18.5N, 77.4E). Choosing where to land a rover is no simple task. As co-chair of the Mars 2020 Landing Site Steering Committee, my team was tasked with narrowing down the more than 30 candidate landing sites proposed and assessed by the science community. After five years examining all the options, Jezero crater was selected.

The 49 km-in-diameter Jezero impact crater is near the western margin of an ancient, very large impact basin named Isidis basin. There is a large water-cut valley that enters the western side of the crater and deposited a broad delta on the margin of an approximately 250-meter-deep lake that filled the crater perhaps 3.5 or 4 billion years ago. The ancient delta and associated lake deposits in Jezero appear analogous to many broadly similar features that form on Earth and that often preserve evidence of past habitability and life. The Mars 2020 rover will land on the now-dry floor of the crater and explore the ancient lake and delta deposits to determine what the ancient lake was like and whether there are any preserved biosignatures related to past occurrence of life on Mars.

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Why NASA Is Headed Back to Mars with Mars Rover Perseverance - Smithsonian

Hitting the reset button | Lifestyles – Enid News & Eagle

Hello again, everyone. It's been a week or two.

I apologize for not writing for the last several weeks; moving takes a lot out of you. Consequently, I wasn't able to see Comet C/2020 F3, aka NEOWISE. Hey, you win some, you lose some.

Either way, I appreciate you all hanging in there with me.

For those of you new to me or my column, I thought it would be appropriate for a bit of a reset. I just want to give everyone an impression of who I am and why I write.

My name is Joe, I'm 34, and I've worked at the Enid News & Eagle since June 2009. No, I am not originally from Enid, and while that makes me an outsider, I appreciate this city and its people, young and old, of all opinions.

I was raised in both Florida in Nebraska. In the former state, I lived so close to Cape Canaveral that I could literally watch space shuttle launches from my driveway. That was what launched (pardon the pun) my initial interest in astronomy. From then on, I read every piece of astronomy literature I could get my hands on. This continued through my teen years, when I became more interested in the UFOs/extraterrestrial life/other solar systems part of astronomy. And I would say that remains my main interest to this day.

Valparaiso University is my alma mater. That's where I got my bachelor's degree in journalism, along with a minor in physics. Between 2004 and 2008, I spent two summers conducting astronomy research at both Valparaiso University and Kitt Peak National Observatory in Arizona. I studied protoplanetary nebulae, which is a sort of stage stars go through at the end of their lives.

In addition to all that, I've always been an avid amateur astronomer. I've never had the resources for a big telescope with fancy astrophotography abilities, and yet my curiosity and passion were nonstop as I scanned the night sky for every single star with my eyepiece.

And that's mainly what this column is about. You don't need a fancy telescope or any other special equipment to enjoy the night sky. In fact, sometimes the best tool is still the naked eye under dark skies. The sky shows us many things: objects both familiar and exotic; stellar birth and death, the life cycle of the universe from beginning to eventual end.

I have not gone anywhere; I will continue to share with all of you one of my most intense passions, the study of astronomy.

Coming from someone who thoroughly knows and has studied the field, trust me, there is always something to learn.

Joe Malan is presentation editor and astronomy writer for the Enid News & Eagle. He can be reached at jmalan@enidnews.com.

We are making critical coverage of the coronavirus available for free. Please consider subscribing so we can continue to bring you the latest news and information on this developing story.

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Hitting the reset button | Lifestyles - Enid News & Eagle

Astronomers Discover One of the Coolest Transiting Gas Giants | Astronomy – Sci-News.com

Using data from NASAs Transiting Exoplanet Survey Satellite (TESS) and the Next-Generation Transit Survey (NGTS), astronomers have discovered a transiting Saturn-like exoplanet circling NGTS-11 (also known as TOI-1847 and 2MASS J01340514-1425090), a mid K-type star located 624 light-years away in the constellation of Cetus. Named NGTS-11b (TOI-1847b), the planet has an equilibrium temperature of just 162 degrees Celsius (324 degrees Fahrenheit), making it one of the coolest known transiting gas giants.

An artists impression of a Saturn-sized exoplanet. Image credit: Sci-News.com.

NGTS-11b has a radius of 0.82 times that of Jupiter and a mass of 0.34 Jupiter masses.

The planet orbits its host star every 35 days at a distance 5 times closer than the Earth is to the Sun.

NGTS-11b has a temperature of only 162 degrees Celsius cooler than Mercury and Venus, said lead author Dr. Samuel Gill, an astronomer in the Centre for Exoplanets and Habitability and the Department of Physics at the University of Warwick.

Although this is still too hot to support life as we know it, it is closer to the Goldilocks zone than many previously discovered planets which typically have temperatures above 1,000 degrees Celsius (1,832 degrees Fahrenheit).

This planet is out at a thirty-five days orbit, which is a much longer period than we usually find them. It is exciting to see the Goldilocks zone within our sights, added Dr. Daniel Bayliss, an astronomer in the Department of Physics at the University of Warwick.

The researchers initially identified NGTS-11b from a single-transit event detected by the TESS spacecraft.

TESS uses the transit method to spot planets, scanning for the telltale dip in light from the star that indicates that an object has passed between the telescope and the star, they explained.

However, TESS only scans most sections of the sky for 27 days. This means many of the longer period planets only transit once in the TESS data. And without a second observation the planet is effectively lost.

The team followed up the system using NGTS telescopes in Chile and observed the host star for 79 nights, eventually catching the planet transiting for a second time nearly a year after the first detected transit.

By chasing that second transit down weve found a longer period planet. Its the first of hopefully many such finds pushing to longer periods, Dr. Gill said.

These discoveries are rare but important, since they allow us to find longer period planets than other astronomers are finding. Longer period planets are cooler, more like the planets in our own Solar System.

The original transit appeared just once in the TESS data, and it was our teams painstaking detective work that allowed us to find it again a year later with NGTS, said Professor Pete Wheatley, an astronomer in the Centre for Exoplanets and Habitability and the Department of Physics at the University of Warwick.

The discovery is reported in a paper in the Astrophysical Journal Letters.

_____

Samuel Gill et al. 2020. NGTS-11 b (TOI-1847 b): A Transiting Warm Saturn Recovered from a TESS Single-transit Event. ApJL 898, L11; doi: 10.3847/2041-8213/ab9eb9

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Astronomers Discover One of the Coolest Transiting Gas Giants | Astronomy - Sci-News.com

A Faraway Solar System Is an Uncanny Reflection of Our Own – The Atlantic

This other solar system looks almost cozy, but these planets are a few hundred times farther from their star than Saturn and Jupiter are from our own. There might be rocky planets like Earth somewhere in this system, Kenworthy said, but they would be too small for even our most powerful telescopes to spot. As far as we can tell, this system is not like our home in the cosmos, and yet its landscape seems somehow familiar, like seeing a photograph of a famous skyline with a few skyscrapers missing. My first thought when I saw this image was, Huh, I wonder how things are going there. Maybe theyre having a better time of it than we are.

Read: The before times of a solar system

This is, I realize, an absurd thoughta knee-jerk projection of pandemic stress at a time when the fight against the coronavirus in the United States feels more frustrating and helpless each day. Our world seems particularly exhausting right now, and these kinds of astronomical observations provide a strange sense of comfort. They present a different version of something recognizable, and an opportunity to imagine a calmer existence, in which the pandemic isnt always on our minds.

Maddalena Reggiani, a postdoctoral researcher at KU Leuven, in Belgium, and one of the researchers in this study, gets a similar feelingnot my desperate wishful thinking about an alternate reality, but the sense that she is looking at a cosmic doppelgnger. This image, after all, resembles how our own solar system appears in textbooks and on classroom posters: as a ball of fire suspended in the darkness, with a few glassy marbles circling it.

To produce the image, Kenworthy and his colleagues compared multiple observations of the solar system. In the first set, the star is surrounded by several blobs of glowing gas, any one of which could be a planet. In the second set, taken some time later, some of the orbs have moved, while others have stayed put, as unmoving as the star itself. The objects that shifted turned out to be other stars, somewhere in the background, moving along on their own journey through space. The objects that stuck around, the researchers concluded, were planets.

Read: A breakthrough way to see distant planets

Astronomers seek out such cosmic doppelgngers to learn about our own history. By studying a baby version of the sun somewhere else, they can better understand how our own adult sunall the planets around itcame to be. Studying images of similar solar systems is like looking at a childhood photo album. We cant, during our lifetime, look at how a planetary system is born and how it evolves, Reggiani told me. All we can do is look at stars at different ages so we can guess a little bit at the history of our solar system.

Cosmic analogues can also help scientists understand the kinds of circumstances that can lead to a planet sprouting life, even if all they see is gas planets capable of producing only swirling cloud tops instead of squirming organisms. Spotting a couple of gas planets in another solar system is not the triumphant discovery that detecting an Earthlike atmosphere on a rocky exoplanet would be, but it is an important bread crumb in the search for life in the universe.

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A Faraway Solar System Is an Uncanny Reflection of Our Own - The Atlantic

Gamma-Ray Telescopes Can Measure the Diameters of Other Stars – Universe Today

In astronomy, the sharpness of your image depends upon the size of your telescope. When Galileo and others began to view the heavens with telescopes centuries ago, it changed our understanding of the cosmos. Objects such as planets, seen as points of light with the naked eye, could now be seen as orbs with surface features. But even under these early telescopes, stars still appeared as a point of light. While Galileo could see Jupiter or Saturns size, he had no way to know the size of a star.

That didnt change until 1995 when the Hubble Space Telescope made an image of Betelgeuse not as a point but as a blurry disk. It was the first time astronomers could determine the size of a star directly. Astronomers could finally compare the apparent size of a star to theoretical calculations based on mass, color, and brightness. Since then, both ground and space-based optical telescopes have imaged stars and even planets directly. But astronomy at other wavelengths posed new challenges.

In radio astronomy, the issue was with the wavelength of radio light. Optical telescopes use light with wavelengths on the order of a few hundred nanometers, the wavelengths used by radio telescopes are typically millimeters or centimeters. Since the resolution of telescope scales with the wavelength of light, a radio telescope would need to be nearly a million times larger to create a sharp image. It isnt feasible to create such a large radio antenna dish. So instead, radio astronomers use a technique known as interferometry.

With radio interferometry, an array of antenna dishes view the same object from widely separated positions. Waves of light from the object at slightly different times, depending on their location. By correlating the antenna signals, astronomers can create a virtual telescope the size of the array. This is what makes observatories such as the VLA and ALMA so powerful. With radio interferometry, astronomers can even create a virtual telescope the size of Earth, which they used to directly image a black hole.

But you dont need to make a high-resolution image of a star to measure its size directly. Recently a team measured the size of two stars, Beta Canis Majoris and Epsilon Orionis, and they did it an array of gamma-ray telescopes known as VERITAS.

While radio wavelengths are much longer than visible light, gamma rays have much shorter wavelengths. So short that gamma rays act almost like particles. When gamma rays strike Earths atmosphere, they can create flashes of optical light called Cherenkov light. VERITAS observes Cherenkov light to study gamma ray astronomy, which is not suited for the type of interferometry used by radio telescopes. So the team repurposed the detectors to use another type of interferometry known as intensity interferometry. With this method, multiple antennas only measure the intensity or brightness of a source, so it doesnt need to worry about the wave property of optical light.

Both Beta Canis Majoris and Epsilon Orionis are blue giant stars. The former is about 500 light-years away, while the latter is 2,000 light-years away. Their apparent sizes are less than a milliarcsecond, which is smaller than the Hubble Space Telescopes resolution. Using this method, the team measured the apparent size of these stars with an uncertainty of less than 5%.

The VERITAS array only contains four antennas, so this is just a first step. With more antennas, this method could be used to create extremely precise observations of distant stars.

Reference: Abeysekara, A. U., et al. Demonstration of stellar intensity interferometry with the four VERITAS telescopes. Nature Astronomy (2020): 1-6.

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Astronomers Capture the First Ever Photo of Two Planets Orbiting a Sun-Like Star – PetaPixel

The European Southern Observatorys Very Large Telescope (ESO VLT) has captured a worlds first: the first ever image of two giant exoplanets orbiting a young Sun-like star 300 light years away from our own. The photograph could provide important information about the formation of our own solar system.

The groundbreaking imagewhich is discussed in detail on the ESO websiteis described as a snapshot of an environment that is very similar to our Solar System, but at a much earlier stage of its evolution.

As the ESO explains, direct observations of exoplanets are exceedingly rare but incredibly important in the search for planets like our own, which might support life. Imaging two exoplanets around the same star is even more remarkable, and capturing an image of two planets orbiting a Sun-like star is a unique accomplishmenta worlds first.

Here is the wide-angle image of the solar system in question:

And here is a closer crop:

The photograph was made possible by using the Very Large Telescopes SPHERE instrument, which uses a coronagraph to block bright light emitted by the star, allowing astronomers to detect and observe the much fainter planets surrounding them.

The image shows a star very much like our own Sun, only far younger, in the top left-hand corner. The two exoplanetsgas giants that are each several times larger than Jupiterare the two bright dots in the middle and bottom right of the image.

Notably, both planets are very far away from their star: one is orbiting at 160 times Earth-Sun distance, and the other at about 320 times Earth-Sun distance. But while this image doesnt show a system similar to ours in the present day, scientists hope that images like this one may shed some light on the early history of our solar system. For the rest of us, theyre just incredible to look at and at least try to fathom.

To learn more, check out the video explainer up top, head over to the ESO blog, or read the full research paper about this image in The Astrophysical Journal Letters.

(via DPReview)

Image credits: All photos by ESO/Bohn et al.

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Thanks to astronomy, researchers in Texas figure out the time, date, and year of Vermeer’s "View of Delft" – Art Critique

Nothing if not technical, Vermeer is known for his expert handling of light and shadow, which has mesmerised many for centuries. However, even today, not a lot is known about the artists life and how he worked, which is how he earned the nickname The Sphinx of Delft and why many of his works remain mysterious. Thus, art historians and scholars have had to speculate their fair share when it comes to his works. A Texas State University physics professor alongside a team of researchers have offered a little more understanding for one of Vermeers paintings, View of Delft.

For decades, there have been relatively few details of the painting articulately depicting Delft, a city in the Netherlands where Vermeer was born, lived, and died. It has consistently been agreed upon that View of Delft was painted during the late spring or summer of 1660, but there has been less consensus on the time of day portrayed by the great painter. Thanks, though, to the work of David Olson, Texas State University astronomer, physics professor emeritus and Texas State University System Regents Professor, Russell Doescher, retired professor in the Department of Physics at Texas State, and students Charles Condos, Michael Snchez, and Tim Jenison, we now know more about the painting.

Vermeers extreme attention to detail when it comes to light and shadow assisted the research team, led by Olson whos been called the celestial sleuth. After more than a year of research, multiple trips to Delft, mapping out the citys features included in Vermeers work, and studying the angle of the sun, they were able to establish what they believe to be the exact time shown in Vermeers work: 8am on September 3rd, 1659 (or possibly 1658).

View of Delft was painted from the second-floor window of an inn where Vermeer stayed to create the work, which shows the octagonal tower of Nieuwe Kerk, or New Church. The tower has long been a point of debate amongst scholars as it was believed to have been increased in size by the Dutch artist, and it proved to be an integral piece to the puzzle for researchers.

Thats our key, Olson said in a press release referring to the octagonal tower. Thats the sensitive indicator of where the sun has to be to do that, to just skim the one projection and illuminate the other. The pattern of light and shadows was a sensitive indicator of the position of the sun.

Through precise measurements taken from high res photos from a similar vantage point to what Vermeer would have seen while painting the work, Olsons team established that the tower was in fact not exaggerated as previously asserted. A thin vertical sliver of light found on the tower allowed the researchers to figure out the exact angle of the sun, which then assisted astronomers in calculating a set of two possible dates: April 6-8 or September 3-4. But which was it? A simple analysis of the work held the answer as the trees, still full of leaves, allowed them to deduce that Vermeer was working during September on the painting.

Vermeer is known to have worked slowly. Completing all the details on the large canvas of his masterpiece may have taken weeks, months or even years, Olson added, recognising Vermeers extreme feat in executing the work. His remarkably accurate depiction of the distinctive and fleeting pattern of light and shadows on the Nieuwe Kerk suggests that at least this detail was inspired by direct observation of the sunlit tower rising above the wall and roofs of Delft.

Ultimately, the discovery offers one more bit of information to help us better understand the celebrated artist, although there is inevitably still much to learn.

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Thanks to astronomy, researchers in Texas figure out the time, date, and year of Vermeer's "View of Delft" - Art Critique

AGC to Complete the Acquisition of MolMed on July 31, 2020 – BioSpace

AGC Biologics adds leading-edge cell & gene therapy company in Milan, Italy

SEATTLE, July 27, 2020 /PRNewswire/ -- AGC Biologics, a Global Biopharmaceutical Contract Development and Manufacturing Organization (CDMO), has announced that they will acquire the majority of the share capital of Molecular Medicine S.p.A. ("MolMed") on July 31, 2020. MolMed is a biotechnology company focused on research, development, production and clinical validation of cell and gene therapies for the treatment of cancer and rare diseases. AGC Biologics is now one of the very few CDMO's in the world offering both plasmid production and end-to-end cell and gene therapy services.

Cell and gene therapy is an innovative and rapidly growing therapeutic field that aims to treat diseases that do not have adequate treatments to date. Approximately 1,000 clinical trials are underway worldwide, with some products receiving market authorization in the last few years and approximately 50 new therapies expected to be authorized by 2030. Thanks to its two commercially authorized facilities, MolMed offers GMP services for the development and production of cell and gene therapies. MolMed brings deep experience and expertise in providing development and GMP manufacturing services for viral vectors and genetically modified cells, from the preclinical phase through commercial demand.

"While we work hard to take care of each other and our customers during this very challenging and uncertain time, it's also important that we ensure the continued growth of our company," says AGC Biologics CEO Patricio Massera. "AGC Biologics is committed to continuously expanding our offerings and growing our capacity to serve all the needs of current and future customers. We are very pleased to be adding MolMed and its great cell and gene therapy capabilities and track record to AGC Biologics' global CDMO service offerings."

About AGC Biologics:AGC Biologics is a leading global Contract Development and Manufacturing Organization (CDMO) with a strong commitment to deliver the highest standard of service to clients and partners. The company currently employs more than 1,000 employees worldwide. AGC Biologics' global network spans three continents, with cGMP-compliant facilities in Seattle, Washington; Boulder, Colorado; Copenhagen, Denmark; Heidelberg, Germany; and Chiba, Japan.

AGC Biologics offers deep industry expertise and unique customized services for the scale-up and cGMP manufacture of protein-based therapeutics, from pre-clinical to commercial mammalian and microbial production. Integrated service offerings include plasmid (GMP pDNA) manufacturing, cell line development, bioprocess development, formulation, analytical testing, antibody drug development and conjugation, cell banking and storage and protein expression, including the proprietary CHEF1 Expression System for mammalian production. Learn more at http://www.agcbio.com.

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AGC to Complete the Acquisition of MolMed on July 31, 2020 - BioSpace

Postdoctoral Researcher, Cognitive and Brain Aging Group job with UNIVERSITY OF HELSINKI | 214656 – Times Higher Education (THE)

INVITATION FOR APPLICATIONS

The Institute for Molecular Medicine Finland (FIMM) is an international research unit focusing on human genomics and personalised medicine at the Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki - a leading Nordic university with a strong commitment to life science research. As part of Academic Medical Center Helsinki in Meilahti campus FIMM collaborates locally with the Faculty of Medicine, Helsinki University Hospital and National Institute for Health and Welfare. FIMM is part of the Nordic EMBL Partnership for Molecular Medicine, composed of the European Molecular Biology Laboratory (EMBL) and the centres for molecular medicine in Norway, Sweden and Denmark, and the EU-LIFE Community.

FIMM is currently seeking a postdoctoral researcher to join Cognitive and Brain Aging group

Description:

Postdoctoral researcher will be working in FIMM Cognitive and Brain Aging group led by Dr. Eero Vuoksimaa. Cognitive and Brain Aging group studies risk and protective factors of old age cognitive impairment and aims to improve early detection and diagnosis of dementia and Alzheimers Disease. We are also interested in healthy cognitive aging and cognitive reserve. Our multidisciplinary approach includes e.g., epidemiology, twins studies, molecular genetics, neuropsychology and brain imaging. We are seeking highly motivated postdoctoral researcher to work in a project that aims to understand the mechanisms of cognitive and brain aging from middle age to the oldest-old. Project is done in close collaboration with national and international researchers including Turku PET Centre and University of California, San Diego.

Postdoctoral researcher will participate in analyzing brain imaging, cognitive and genetic data, conducting statistical analyses, presenting in scientific conferences, writing of research manuscripts and in grant writing.

Qualifications and experience:

Candidates should have a PhD in neuropsychology, neurosciences, psychology, genetics or related field. Candidates with track record in processing and analyzing structural brain imaging data and/or experience in twin research / molecular genetics will be preferred. Ideal candidate has expertise also in Alzheimers disease and/or cognitive aging. Proficiency in spoken and written English is required.

Salary and contract:

The salary will be commensurate with qualifications based on the Finnish university salary (YPJ) system on previous qualifications, experience and performance in the position. The contract will be offered for one year with a possibility for extension for a second year. Full time fixed-term position is available from September 2020 or as agreed. Due to coronavirus situation the position may be started remotely.

To apply, please submit the application, together with your CV and a 1 page motivation letter, through the University of Helsinki electronic recruitment system by clicking on Apply for job. Internal applicants (i.e., current employees of the University of Helsinki) please submit your applications through the SAP HR portal.

Attach motivation letter and CV as a single PDF file. CV should include name and contact information of two referees and the list of publications with highlighting up to five most important papers and describing candidates role in these papers. Please indicate your experience in brain imaging and/or behavior/molecular genetics in the motivation letter and indicate why you want to study cognitive aging.

Please apply no later than 3.8.2020. Interviews will be conducted either in-person or online.

For further information please visit our website at http://www.fimm.fi or contact Dr Eero Vuoksimaa at eero.vuoksimaa@helsinki.fi

If you need support with the recruitment system, please contact recruitment@helsinki.fi. Please contact hr-hilife@helsinki.fi for other process-related questions.

Due date

03.08.2020 23:59 EEST

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Postdoctoral Researcher, Cognitive and Brain Aging Group job with UNIVERSITY OF HELSINKI | 214656 - Times Higher Education (THE)

Researchers uncover how cells interact with supporting proteins to heal wounds – Washington University in St. Louis Newsroom

When we get a wound on our skin, the cells in our bodies quickly mobilize to repair it. While it has been known how cells heal wounds and how scars form, a team led by researchers from Washington University in St. Louis has determined for the first time how the process begins, which may provide new insight into wound healing, fibrosis and cancer metastasis.

The team, led by Delaram Shakiba, a postdoctoral fellow from the NSF Science and Technology Center for Engineering Mechanobiology (CEMB) at the McKelvey School of Engineering, discovered the way fibroblasts, or common cells in connective tissue, interact with the extracellular matrix, which provides structural support as well as biochemical and biomechanical cues to cells. The team uncovered a recursive process that goes on between the cells and their environment as well as structures in the cells that were previously unknown.

Results of the research were published in ACS Nano on July 28. Senior authors on the paper are Guy Genin, the Harold and Kathleen Faught Professor of Mechanical Engineering at the McKelvey School of Engineering, and Elliot Elson, professor emeritus of biochemistry and molecular biophysics at the School of Medicine.

Clinical efforts to prevent the progression of fibrocontractile diseases, such as scarring and fibrosis, have been largely unsuccessful, in part because the mechanisms that cells use to interact with the protein fibers around them are unclear, Shakiba said. We found that fibroblasts use completely different mechanisms in the early and I think the most treatable stages of these interactions, and that their responses to drugs can therefore be the opposite of what they would be in the later stages.

Genin, who is the co-director of the CEMB, said the process has stymied mechanobiology researchers for some time.

Researchers in the field of mechanobiology thought that cells pulled in collagen from the extracellular matrix by reaching out with long protrusions, grabbing it and pulling it back, Genin said. We discovered that this wasnt the case. A cell has to push its way out through collagen first, then instead of grabbing on, it essentially shoots tiny hairs, or filopodia, out of the sides of its arms, pulls in collagen that way, then retracts.

Now that they understand this process, Genin said, they can control the shape that a cell takes.

With our colleagues at CEMB at the University of Pennsylvania, we were able to validate some mathematical models to go through the engineering process, and we now have the basic rules that cells follow, he said. We can now begin to design specific stimuli to direct a cell to behave in a certain way in building a tissue-engineered structure.

The researchers learned they could control the cell shape in two ways: First, by controlling the boundaries around it, and second, by inhibiting or upregulating particular proteins involved in the remodeling of the collagen.

Fibroblasts pull the edges of a wound together, causing it to contract or close up. Collagen in the cells then remodels the extracellular matrix to fully close the wound. This is where mechanobiology comes into play.

Theres a balance between tension and compression inside a cell that is newly exposed to fibrous proteins, Genin said. There is tension in actin cables, and by playing with that balance, we can make these protrusions grow extremely long, Genin said. We can stop the remodeling from occurring or we can increase it.

The team used a 3D-mapping technique the first time it has been applied to collagen along with a computational model to calculate the 3D strain and stress fields created by the protrusions from the cells. As cells accumulated collagen, tension-driven remodeling and alignment of collagen fibers led to the formation of collagen tracts. This requires cooperative interactions among cells, through which cells can interact mechanically.

New methods of microscopy, tissue engineering and biomechanical modeling greatly enhance our understanding of the mechanisms by which cells modify and repair the tissues they populate, Elson said. Fibrous cellular structures generate and guide forces that compress and reorient their extracellular fibrous environment. This raises new questions about the molecular mechanisms of these functions and how cells regulate the forces they exert and how they govern the extent of matrix deformation.

Wound healing is a great example of how these processes are important in a physiologic way, Genin said. Well be able to come up with insight in how to train cells not to excessively compact the collagen around them.

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Strata Oncology Announces Partnership with BioMed Valley Discoveries to Accelerate Enrollment in ERK Inhibitor Study – BioSpace

ANN ARBOR, Mich., July 29, 2020 /PRNewswire/ --Strata Oncology, Inc. , a precision oncology company advancing molecular indications for cancer therapies, today announced it has signed an agreement with BioMed Valley Discoveries Inc.. to accelerate patient identification and enrollment for BioMed Valley's Phase 2 study of BVD-523 (ulixertinib) for patients with advanced malignancies harboring MEK or atypical BRAF alterations (non-BRAF V600E mutations).

Ulixertinib is a first-in-class potent and selective small molecule inhibitor of ERK1/2. BioMed Valley reported positive preliminary Phase I data for ulixertinib in patients harboring MAPK alterations, including atypical BRAF alterations.

Under the terms of the agreement and through the Strata Trial, Strata Oncology will identify patients with advanced solid tumors that harbor mutations in the MAPK signaling pathway and meet other eligibility criteria, for consideration of enrollment into BioMed Valley's Phase 2 study. The Strata Trial, an ongoing observational study providing tumor molecular profiling for patients with advanced cancer paired with a portfolio of biomarker-guided clinical trials, is available across a network of 25+ select health systems nationwide. Through the Strata Trial, patients with advanced cancer are profiled using StrataNGSTM, a comprehensive molecular profiling test optimized for performance on tissue samples as small as 0.5mm2 surface area.

"This partnership with BioMed Valley Discoveries supports our commitment to improving the lives of patients with cancer by providing local access to promising investigational therapies," said Dan Rhodes, Ph.D., CEO of Strata Oncology. "We are confident our network of health system partners, standardized on the Strata Trial, will help drive rapid enrollment of this important study."

David Chao, President & CEO of BioMed Valley Discoveries, commented,"We are delighted to collaboratewith Strata to developourfirst-in-class ERK inhibitor. Strata's ability to rapidly identify patients with specific tumor mutations has the potential to dramatically accelerate the recruitment of patients for our trial."

For more information about BioMed Valley's BVD-523 study, please visit clinicaltrials.gov.

About Strata OncologyStrata Oncology, Inc. is a precision medicine company dedicated to transforming cancer care by building a platform to systematize precision oncology across a network of health systems and pharma companies. Strata empowers health systems to deliver a cost-effective, system-wide, precision oncology program, one that integrates cutting-edge molecular profiling and precision therapy trials with routine care, so that all advanced cancer patients have the opportunity to benefit. This large network of trial-ready health systems provides a mechanism to rapidly and predictably enroll precision therapy trials. For more information visitwww.strataoncology.com.

Strata Inquiries:Renee Volpini(917) 923-8117renee.volpini@icrinc.com

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SOURCE Strata Oncology, Inc.

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Strata Oncology Announces Partnership with BioMed Valley Discoveries to Accelerate Enrollment in ERK Inhibitor Study - BioSpace

BioMed Valley Discoveries ulixertinib (BVD-523), a first-in-class ERK inhibitor cancer therapy, receives Fast Track designation and launches Phase II…

Newswise Kansas City, MO. BioMed Valley Discoveries (BVD), a clinical stage biotechnology company, announces the receipt of Fast Track designation from the US Food and Drug Administration (FDA) for investigation of the ERK inhibitor ulixertinib (BVD-523) as a treatment for patients with non-colorectal, solid tumors that harbor BRAF mutations G469A/V, L485W, or L597Q. BVD has launched a Phase II multi-center study of ulixertinib for patients with advanced malignancies harboring these atypical (non-V600) BRAF alterations or a MEK alteration.

The Phase II effort builds on a successful Phase Ib evaluating ulixertinib as a novel targeted cancer treatment in cohorts of patients with specific genetic alterations that result in aberrant MAPK pathway signaling. Results from Phase Ib showed that ulixertinib has an acceptable safety profile and early evidence of clinical activity against a wide range of tumor types exhibiting mutations in the MAPK pathway, including atypical alterations in BRAF.

BVD is pleased to announce that Cmed, Inc., will serve as the contract research organization (CRO) for the Phase IIb study. BVD is also collaborating with Strata Oncology to identify and obtain study patients with Stratas Precision Oncology Network. This network of trial-ready health systems features a database of matched trial candidates that will allow for rapid and efficient identification of potential patients.

David Chao, PhD, president and CEO of BVD, comments, We are pleased with the receipt of Fast Track designation for ulixertinib and delighted to collaborate with Cmed and Strata to develop this promising first-in-class ERK inhibitor.

This study (NCT04488003) is currently expected to begin enrollment in Q3 2020.

About ulixertinib(BVD-523): Ulixertinib is a first-in class and best-in class small molecule inhibitor ofextracellular signal-regulated kinase (ERK)family kinases (ERK1 and ERK2) thatis being developedas a novel anti-cancer drug. ERK kinases are downstream components of themitogen-activated protein kinase (MAPK)signaling cascade (RAS-RAF-MEK-ERK). Ulixertinib has demonstrated promising early efficacy for patients with tumors harboring alterations in the MAPK pathway, including atypical (non-V600) BRAF alterations, for which there are currently no approved targeted agents.

About Fast Track status: Fast Track is a designation by the FDA of an investigational drug for expedited review to facilitate development of drugs which treat a serious or life-threatening condition and fill an unmet medical need. Fast Track status entails eligibility for Accelerated Approval and Priority Review if certain criteria are met as well as more frequent interactions with the FDA.

About the study: This Phase II study expands upon the ulixertinib Phase I signal to evaluate the utility of ulixertinib to treat patients with tumors harboring an atypical BRAF alteration. Furthermore, the potential to treat MEK1/2 mutant cancers will also be explored. This patient population is rare (<1% of cancers), however a strong scientific rationale exists to treat patients harboring putatively activating MEK1/2 alterations with ERK inhibition. Part A of the trial is tumor histology agnostic, with patients enrolled in one of six groups based on their tumor alteration. Part B of the trial is tumor histology specific, enrolling patients with one of up to three specified tumor histologies based on evolving part A data.

About Cmed: Cmed, established for 20 years, is a global technology-led full-service CRO specializing in complex disease areas, particularly oncology, immuno-oncology, cell therapy, and other specialty therapeutics areas. Cmed has built a reputation for delivering these clinical trials with expertise, and a personalized, flexible approach, and a mission to contributing to the development of innovative medicines for the benefits of the patients. Cmed has a strong data management and statistics heritage. As well as being a Functional Service Provider of these services, via its Cmed Technology business (part of Cmed Group), Cmed has developed and uses an advanced, enterprise, cloud based clinical data system,encapsia.encapsiadelivers a complete solution to gather and manage multiple live clinical data sources and apply real-time data management, sophisticated visualizations, analytics, and AI. Client benefits include informed trial progress, deep insights into their data to support timely management decisions, and particularly relevant with the disruption caused by the COVID-19 pandemic, able to support remote, decentralized, and virtual trial conduct. For more information, visitwww.cmedresearch.comandwww.encapsia.comor contactInfo@cmedgroup.com.

About Strata Oncology: Strata Oncology, Inc. is a precision medicine company dedicated to transforming cancer care by building a platform to systematize precision oncology across a network of health systems and pharma companies. Strata empowers health systems to deliver a cost-effective, system-wide, precision oncology program, one that integrates cutting-edge molecular profiling and precision therapy trials with routine care, so that all advanced cancer patients have the opportunity to benefit. This large network of trial-ready health systems provides a mechanism to rapidly and predictably enroll precision therapy trials. For more information, visit http://www.strataoncology.com.

About the Strata Precision Oncology Network: The Strata Precision Oncology Network (Network), led by Strata Oncology, is a collaborative network of leading health systems that believe in deploying a clinical-research driven model for precision medicine that enables continuous learning to drive research and clinical care. The Network consists of 25 leading health systems that have demonstrated a commitment to standardizing tumor molecular profiling and precision therapy trials, providing a platform to accelerate drug approvals and catalyze new clinical research opportunities. The Strata Trial serves as the foundation of this approach by providing a standardized genomic testing protocol to deliver precision oncology system-wide.

About BioMed Valley Discoveries (BVD): BioMed Valley Discoveries is a clinical stage biotechnology company focused on addressing unmet medical needs in a variety of therapeutic and diagnostic areas. In addition to the ERK inhibitor, BVDs portfolio includes an oncolytic bacteria that has completed enrollment for a Phase I study, a selective phosphoinositide 3-kinase gamma inhibitor in late preclinical testing, and two early-stage antibodies targeting the tumor microenvironment.

Operating since 2007, BioMed Valley Discoveries was established by Jim Stowers Jr., founder of the asset management firm American Century Investments, and his wife Virginia, to advance new medical innovations to improve the lives of patients with difficult-to-treat diseases. BVD is owned by a supporting organization of the Stowers Institute for Medical Research, a non-profit, basic biomedical research organization. Since 2000, the endowment of the Stowers Institute has received over $1.5 billion in dividend payments from American Century. The Institute has invested a portion of its endowment in BVD, whose profits accrue to the benefit of the Institute. For more information, visit http://www.biomed-valley.com.

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BioMed Valley Discoveries ulixertinib (BVD-523), a first-in-class ERK inhibitor cancer therapy, receives Fast Track designation and launches Phase II...

Why it is time to invest in Ethereum – Nairametrics

Ethereum (ETH) whales have been active lately. Data feed on advanced crypto tracker Whale alert revealed whales moved 935,746 ETH worth $255,458,658 in 8 transactions within minutes showing a large number of transactions taking place in the Ethereum market.

READ: What will you investN1 millioninif you have the following options?

Quick fact; In the ETH industry, traders or investors who own a large number of ETH are typically called ETH whales. This means an ETH whale would be a single Ethereum address owning around 1,000 Ethereum or more.

Data obtained from Coinmarketcap, revealed Ethereum is the second most valuable cryptocurrency with a market capitalization of $30.5 billion, trading at $272.61 up 3.5%, at the time this report was drafted.

READ MORE: $945 millionworth of BTCsoptions expiring this week

Is it time to buy ETH? With ETH finally breaking out of its long $200-$250 daily close range, it is time to revisit its historical model that illustrates the number of times a daily close transition has occurred between psychological support levels.

ETH is sitting in its sweet spot where the most polarization has historically unfolded (between the $200 and $300 levels) during its five-year history. A close above $300 in the near future would be the 42nd instance of the price closing above or below it.

READ ALSO: Satoshi Nakamotos unspent BTCs worth $10.9 billion

ETH is a cryptocurrency designed for decentralized applications and deployment of smart contracts, which are created and operated without any fraud, interruption, control or interference from a third party.

Ethereum is a decentralized system, fully independent, and is not under anybodys authority. It has no pivotal point, and its platform is connected to thousands of its users through their computing system around the world, which means its almost impossible for ETH to go offline.

READ MORE: Aliko Dangote and his slide from $25 billion to $7 billion

Like with many other crypto assets, speculating with Ethereum can be highly profitable and has had a good history of giving its investors huge returns. However, there are also many other options to make income from Ethereum. These options include Ethereum mining, Ethereum faucets, and ETH staking.

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Why it is time to invest in Ethereum - Nairametrics

Psychedelic Therapy Offers a Synergy of Biological, Psychosocial Interventions – Psych Congress Network

When it comes to mental health treatment, there have been two basic, and often opposing, views as to the best approach: pharmaceutical or psychotherapeutic. Psychedelic therapy is a treatment option that unites both, Robin Carhart-Harris, PhD, explained at the 2020 virtual Psych Congress Elevateconference.

You have the drug camp, and then you have the psychotherapy camp, and they dont really get on. In fact, they often fight, said Dr. Carhart-Harris, head of the Centre of Psychedelic Research at Imperial College London in England. Wouldnt it be wonderful if we had an intervention that was biological, that truly affected the brain on a direct level and also opened things up for therapeutic work? The argument is that psychedelic therapy really does that well in a synergistic way.

See a clip of the session here.

During his session, Dr. Carhart-Harris characterized psychedelic therapy as quintessentially biopsychosocial. When used in the appropriate context with professional support, psychedelics such as psilocybin, DMT, and LSD offer promise for helping people undo negative habits or biases associated with a range of mental health disorders to achieve improved well-being, according to the presentation.

Coined in the 1950s, the term psychedelic means to reveal the mind or soul. Molecularly, psilocybin, DMT, and LSD are similar to serotonin, which modulates a number of key functions in the brain, Dr. Carhart-Harris explained. The mechanism of action of psychedelic drugs appears to involve serotonin 2A receptors in the cortex. Serotonin 2A receptor agonism via psychedelic compounds stimulates plasticity and adaptability in the brain, and can create what Dr. Carhart-Harris termed pivotal mental states of pure plasticity.

The key question is, what do you do with that plasticity? he said. If someone spiked your drink at Burning Man, you might trip out and have a psychotic episode, and things arent going to go well. But if you take a psychedelic with a perfectly nurturing, supportive pair of therapists or guides, it could be really beneficial.

You could explore the furthest reaches of your mind and release a lot of trauma and repressed material, work through it, and come upon insights that are healthy and useful to improving mental health.

Psilocybin shows promise for improving well-being and easing symptoms of depression, addiction, end-of-life distress, and obsessive-compulsive disorder. The environment a psychedelic drug is administered in, however, is important. In an optimal context, therapeutic guides prepare patients, sit with them during the experience, and talk with them afterward to help glean insights and integrate lessons. Trait absorption, therapeutic intentions, and listening to music all appear to affect emotional breakthrough and long-term outcomes.

I saw negative patterns in my life where if something bad happens, I used to just put it to the back of my mind, recalled a patient with treatment-resistant depression who received psilocybin therapy in a trial. Afterwards, I allowed myself to experience everythingeven if it is sadness. Now I know how to deal with my feelings rather than repress them.

MORE: Psych Congress Takes Deep Dive Into Psychedelics

One participant described openly crying during psilocybin therapynot in pain, but like a washing, a washing out. Another described a renewed ability to experience beauty after receiving psilocybin therapy. Although that study was open-label, the effect sizes of psilocybin in patients with treatment-resistant depression were huge, Dr. Carhart-Harris said.

More recently, he and colleagues performed a double-blind randomized controlled trial comparing two session of psilocybin therapy with 6 weeks of the antidepressant escitalopram. He urged conference attendees to watch for published findings.

The results are really excitingPsilocybin therapy comes out very well in this trial, Dr. Carhart-Harris said with a quick smile. I wish I could say more, but I cant. But the safety and efficacy outcomes are really, really promising.

Jolynn Tumolo

Reference

Therapeutic Mechanisms of Psychedelics: Changing the Landscape of Psychiatric Treatment? Presented at Psych Congress Elevate: Virtual; July 26, 2020.

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Psychedelic Therapy Offers a Synergy of Biological, Psychosocial Interventions - Psych Congress Network