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Adele’s Doctor Details Healthy Diet That The Singer Took To Help Her Lose Weight – Medical Daily

Posted on May 15, 2020 by Danzig

Earlier this month, 15-time Grammy winner and esteemed artist Adele wowed the world when she showed off her slimmed-down figure out of nowhere. Thankfully, her doctor shared the singers tips and tricks in order to achieve her type of weight loss in a successful and healthy way shortly after the reveal.

Adeles Doctor Reveals How Singer Lost Weight In A Healthy Way

Winning the esteemed Grammy award 15 times in her ongoing career, Adele is best known for writing songs and ballads that explore lost love, heartbreak and finding ones self after. Shes also known for her powerhouse voice, which only helps in taking her songs to new heights.

But it seems like she still has more surprises up her sleeve since the singer recently wowed everyone by unexpectedly posing a photo showing her slimmed-down figure earlier this month. Shortly afterwards, Dr. Dominique Fradin-Read, her own doctor, revealed just how the singer managed to lose all that weight. Fradin-Read is MD-board certified in preventative medicine and anti-aging medicine with a university degree in nutrition .

I start by telling my patients that when it comes to weight loss, diet and exercisealonewill not be enough in most cases. That is why many patients that come to us have tried to lose weight, they did lose somewhat but put everything back on and often even more.For a successful and sustainable weight loss, we need to look at the whole person and not just address the weight upfront, the physician said.

I combine all the tools and methods in our therapeutic arsenal, starting with the most natural approaches and lifestyle changes, vitamins/supplements, to recommending peptides, rebalancing hormones and finally prescribing medications as appropriately for each patient, she added, saying that after starting her process with the patients, she works toward more intensive treatment.

As for what to eat, Fradin-Read suggested a diet made up of nutrient-rich food as well as protein, good fats, good carbohydrates, dairy and a few wine glasses a week. Green veggies should also take around two-third of the plate. One-third should be for protein, while the remaining space should be for carbs. She also suggested following the well-known Mediterranean diet.

Obesity may occur because of genetics, family history, environment and medical conditions, among other reasons that affect body weight. Pixabay

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Adele's Doctor Details Healthy Diet That The Singer Took To Help Her Lose Weight - Medical Daily

The medical Adele reveals the secret to his weight loss and it is not the exercise – Play Crazy Game

Posted on May 29, 2020 by Danzig

Dominique Fradin-Read is the doctor who has achieved that Adele has lost weight over 70 kilos in the last few months. A radical change which, until now, prevented millions of people from all over the world guessing, as no one knew how it had been accomplished. Now, the doctor has revealed to you what is your trick to slimming down and has made it clear that this is not sport.

The artist is unrecognizable after undergoing a slimming process in which your doctor, based in Los Angeles, has had much to do. Fradin-Read has shared the secret that you use with all their clients, insisting that it is not only exercise, but the process has a lot to do with the mood and mental health.

The products are high in saturated fats or refined carbohydrates, and add a lot of calories may boycott our plan to lose weight

Dominique Fradin-Read has explained to US Weekly weight loss is not just exercisebut the sport should be a part of a transformation of the broader lifestyle of the person. That is why, ensures that the mental health and well-being of those who want to lose weight are just as important as the diet and physical exercise.

The doctor points out that the first thing I tell my patients is that, in regards to weight loss, diet and exercise alone will not be sufficient in the majority of cases. It is one of the reasons that many people suffer from the dreaded rebound effect after submitting to a diet, recovering all the lost weight.

Dr. Fradin-Read stresses the importance of the study to each patient from a global point of view, not only thinking about slimming

However, in addition to focusing on weight loss you have to do it in the persons life in general: Many patients who come to us tried to lose weight previously, but did not succeed and it was recovered, and even more. For successful weight loss and sustainable, we must look at the person in whole and not only addressing the weight separately.

Thats why, subject each patient to a detailed study: We analyzed the metabolic function: how the patient is beginning to develop insulin resistance? We observed the hormone, such an important part of the weight gain in the menopause. We investigated the levels of thyroid and cortisol. We have in mind the habits: why do most of us behave well all day and we crashed for the night? We evaluate the stress and sleep. We talk about mood and mental health. When addressing all of these elements, then we can start a custom diet and to recommend the exercise as needed, Then work.

Fradin-Read does not want to talk explicitly about Adele, because he has moral and legal obligations to protect the privacy of all patients, both mine as others. For that reason, I can not confirm nor deny any informationbut yes, I like to talk about my work as a health and various treatments, therapies, products and services offered by my practice, but do not provide information about specific individuals.

Dr. Fradin-Read is licensed in preventive medicine and anti-aging, in addition to possessing a university degree in nutrition. Part of its success lies in the fact that, when he starts working with a patient, what makes it so intensive: I Combine all the tools and methods in our therapeutic arsenal, starting with approaches that are more natural and changes in lifestyle, vitamins / supplements, to recommend peptides, rebalance hormones, and finally prescribe medications that are appropriate for each patient.

A handful of nuts each day is indicated in any weight loss plan for its magnificent nutritional qualities

One of the tips that you share with all your customers is embrace the mediterranean diet, as well as the healthy menus suggested by the chef, Michel Gurard: the objective is to create balanced meals and customized for each client. The doctor develops a method for visual to make all of you to imagine a plate divided into several parts: green vegetables should occupy approximately two-thirds of the plate; protein-good source of one-third and the last part is reserved to the carbs. And, in addition, you can add healthy fats, such as olive oil, avocado or nuts.

Fradin-Read also emphasizes that the notion of the pleasure of eating is at the base of a successful diet in the long term. For this reason, it is important to create a personalized diet for each person and that is not always the sameWe are all different when it comes to our weight and, therefore, the same diet that works for one person might not work at another; it may even be that not even serve for the same person during all his life.

First recommend structural changes in the style of life, rebalancing the hormones and finally, prescribe appropriate drugs

A good diet to lose weight, according to dr. Fradin-Read, would be comprised of foods that are rich in nutrients, protein, good carbs, healthy fats and dairy. You can even add a glass of wine any day of the week. The goal is that people find good about yourself and maintain that commitment throughout his life.

Thats why, along with their processes of thinning, the american medical also offers a program anti-aging and skin rejuvenation. It does this by means of a test to assess the DNA of each person that enables you to identify the strengths and weaknesses that the body will have in the future. A formula called TruAge that aims to find biomarkers that will allow you to detect in advance various conditions such as cardiovascular disease, Alzheimers disease, cancer and others.

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The medical Adele reveals the secret to his weight loss and it is not the exercise - Play Crazy Game

$184.4M Squalene Market by Source Type, Vegetable Source, Biosynthetic, End-use Industry and Region – Global Forecast to 2025 – PRNewswire

Posted on August 22, 2020 by Danzig

DUBLIN, Aug. 21, 2020 /PRNewswire/ -- The "Squalene Market by Source Type (Animal Source (Shark Liver Oil), Vegetable Source (Olive Oil, Palm Oil, Amaranth Oil), Biosynthetic (GM Yeast]), End-use Industry (Cosmetics, Food, and Pharmaceuticals), and Region - Global Forecast to 2025" report has been added to ResearchAndMarkets.com's offering.

The global squalene market was worth USD 140 million in 2019 and is projected to reach USD 184.4 million by 2025, growing at a CAGR of 7.3% between 2020 and 2025.

The growth in the cosmetics and pharmaceutical industry is expected to drive the squalene market.

The squalene market is driven mainly by increasing sales of cosmetics and pharmaceuticals. The growing cosmetics industry in emerging markets such as Brazil, China, and India; increasing consumer awareness of the usage of high-quality cosmetic products; and willingness to pay premium prices are driving the cosmetics industry at the global level.

The growth in the pharmaceutical industry will be a major driver for the demand for squalene in the future. Increasing R&D in the oncology segment along with increasing spending on oncology medicine is expected to drive the market for squalene in the coming years. Additionally, the rising awareness about the beneficial properties of squalene such as anti-oxidation, anti-aging, strengthening of the immune system, and UV protection is driving the growth of the market.

Biosynthetic expected to be the fastest-growing segment of the squalene market, in terms of value, between 2020 and 2025.

The biosynthetic segment is expected to witness the highest growth in terms of value during the forecast period. With skepticism about the shark liver oil sourced from sharks and low concentration of squalene in vegetable sources, the supply is fluctuating, keeping the prices volatile.

As several limitations are introduced for shark fishing, the supply of squalene has been majorly affected. While in the vegetable sources, squalene content is very low. Therefore tons of olives and amaranth are required to produce a small quantity of squalene.

Collectively, these reasons have led to high squalene retail prices. Hence, sugarcane and other sugar-containing bio-materials have been identified as a source for producing squalene. This biosynthetic squalene is available at relatively lower prices; thus, the market for biosynthetic squalene is expected to grow at a high rate during the forecast period.

The cosmetics industry is estimated to account for the largest share of the overall squalene market, in terms of value, between 2020 and 2025.

Cosmetics is the largest end-use industry of squalene due to its increasing usage in skincare products manufacturing. The demand for natural cosmetics with good quality has been the main driver for the growth of the market. The various beneficial properties and the natural occurrence of squalene is another factor responsible for the growth of this market. APAC primarily drives the growth of squalene containing products. The rising consumer awareness of using high-quality products and willingness to pay a premium price for the products are the major factors driving the demand.

A strong foothold of cosmetics manufacturers in France to drive the demand for squalene in Europe.

Europe's squalene market is estimated to be the largest during the forecast period. Due to the strong foothold of the key cosmetics product manufacturers and high demand for premium beauty products. The demand for high-quality products from cosmetics, food supplements, and pharmaceutical end-use industries is driving the squalene market in the region. The market witnessed a shift from animal-sourced squalene to vegetable-sourced squalene in the past years. The trend is anticipated to remain the same in the forecast period.

France accounted for the largest share in the region, followed by Germany, the U.K., Italy, and Spain. The high-spending power of consumers and the increasing demand for luxury products will continue to drive the squalene market in the region during the forecast period.

Research Coverage

This report segments the market for squalene based on source type, end-use industry, and region, and provides estimations for the overall market size across various regions. A detailed analysis of key industry players has been conducted to provide insights into their business overviews, products & services, key strategies, associated with the market for squalene.

The key players profiled in the report include as Sophim (France), New Zealand GreenHealth Limited (New Zealand), Kishimoto Special Liver Oil Co. Ltd. (Japan), Amyris (US), Ekiz Olive Oil & Soap Inc. (Turkey), SeaDragon Marine Oils Limited (New Zealand), Nucelis LLC (US), Arista Industries Inc. (US), Empresa Figueirense de Pesca, Lda (Portugal), and Arbee BiomarineExtracts Pvt. Ltd. (India).

Key Topics Covered

1 Introduction

2 Research Methodology

3 Executive Summary3.1 Squalene Market: Realistic, Pessimistic, Optimistic, and Non-COVID-19 Scenario3.1.1 Non-COVID-19 Scenario3.1.2 Optimistic Scenario3.1.3 Pessimistic Scenario3.1.4 Realistic Scenario

4 Premium Insights4.1 Significant Opportunities in the Squalene Market4.2 Squalene Market, by Region4.3 Europe: Squalene Market, by End-use Industry and Country4.4 Squalene Market, by End-use Industry4.5 Squalene Market Attractiveness4.6 Squalene Market, by Source Type and Region

5 Market Overview5.1 Introduction5.2 Market Dynamics5.2.1 Drivers5.2.1.1 Beneficial Properties of Squalene for Human Health5.2.1.2 Growth in Pharmaceutical and Cosmetic Industries5.2.2 Restraints5.2.2.1 Consumer Skepticism About Animal-Sourced Products and Limitations on Shark Fishing5.2.2.2 Volatile Supply of Raw Materials5.2.3 Opportunities5.2.3.1 New Renewable Sources for Squalene Production5.3 Porter's Five Forces Analysis5.4 Economic Pandemic due to COVID-195.4.1 Impact of COVID-19 on the Cosmetics Industry5.4.1.1 Impact on Customers' Output and Strategies to Resume/Improve Production5.4.1.2 Customers' Most Affected Regions5.4.1.3 Analyst Viewpoint on Growth Outlook and New Market Opportunities

6 Squalene Market, by Source Type6.1 Introduction6.2 Animal Source6.3 Vegetable Source6.4 Biosynthetic

7 Squalene Market, by End-use Industry7.1 Introduction7.2 Cosmetic7.3 Food7.4 Pharmaceutical7.5 Others

8 Squalene Market, by Region8.1 Introduction8.2 Europe8.3 APAC8.4 North America8.5 Middle East & Africa8.6 South America

9 Competitive Landscape9.1 Introduction9.2 Competitive Leadership Mapping, Tier 1 Companies9.2.1 Visionary Leaders9.2.2 Innovators9.2.3 Emerging Companies9.3 Strength of Product Portfolio9.4 Business Strategy Excellence9.5 Competitive Leadership Mapping (Small and Medium-Sized Enterprises)9.5.1 Progressive Companies9.5.2 Responsive Companies9.5.3 Dynamic Companies9.5.4 Starting Blocks9.6 Strength of Product Portfolio9.7 Business Strategy Excellence9.8 Market Share Analysis9.8.1 Kishimoto Special Liver Oil Co. Ltd.9.8.2 Sophim9.9 Competitive Scenario9.9.1 New Product Launch9.9.2 Expansion

10 Company Profiles10.1 Seadragon Marine Oils Limited10.2 Amyris10.3 Arbee Biomarine Extracts Pvt. Ltd.10.4 Sophim10.5 Kishimoto Special Liver Oil Co. Ltd.10.6 Empresa Figueirense de Pesca, LDA10.7 Nucelis LLC10.8 Arista Industries10.9 Ekiz Olive Oil & Soap Inc.10.10 New Zealand Green Health Ltd.10.11 Other Key Players10.11.1 RLR Squalene10.11.2 Cabomer Inc.10.11.3 Blueline Foods Pvt. Ltd.10.11.4 Coastal Aquatic Proteins10.11.5 Globalab10.11.6 Squalop10.11.7 CN Lab Nutrition10.11.8 Isho Genki International

For more information about this report visit https://www.researchandmarkets.com/r/70tati

Research and Markets also offers Custom Research services providing focused, comprehensive and tailored research.

Media Contact:

Research and Markets Laura Wood, Senior Manager [emailprotected]

For E.S.T Office Hours Call +1-917-300-0470 For U.S./CAN Toll Free Call +1-800-526-8630 For GMT Office Hours Call +353-1-416-8900

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$184.4M Squalene Market by Source Type, Vegetable Source, Biosynthetic, End-use Industry and Region - Global Forecast to 2025 - PRNewswire

The One Spice That May Actually Help Reduce Skin Inflammation, According To Doctors – SheFinds

Posted on January 15, 2022 by Danzig

For better or for worse, what you eat really does impact your skin. If youre experiencing inflamed skin this winter, weve reached out to health experts, doctors and dietitians and learned more about an all-natural spice that is not only an antioxidant, but also has the power to reduce skin inflammation. Read on for more information on its many skin and health benefits, and expert-approved meal ideas containing this special ingredient.

Turmeric is a spice that derives from the root of the curcuma longa plant, and a perennial in the ginger family. It iscultivated in many states in India and other East Asian nations. As dermatologist Dr. Purvisha Patel, M.D. explains, it is a beloved and historically used tool in skincare and healthy eating.

Turmeric hasbeen used for centuries in Eastern medicine to combat cancers, auto-immune diseases and skin conditions such as psoriasis, vitiligo and acne, says Patel. It has been shown in scientific studies time and time again to help skin conditions, both when ingested and used topically.

Patel notes that turmerics bright yellow color can be attributed to Curcumin, its active ingredient. Curcumin is anti-inflammatory, anti-micribial, anti-neoplastic and has antioxidant properties, as it combats free radical damage, says Patel.

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Registered dietitian and nutritionist Susan Kelly reiterates that turmeric contains the component Curcumin that gives it a distinct colorand taste. It is used in various modern-day medicines, she says, because of its strong anti-inflammatory, anti-oxidant, anti-fungal, anti-bacterial properties.

"Aging and other skin inflammatory diseases are caused by oxidative damage," says Kelly. "In this process, free radicals react with organic substances, which can cause skin damage."

Curcumin, Kelly says, not only fights these radicals but also "stimulates the antioxidant mechanism in our body," which makes it the "best choice" to fight against skin inflammation and other skin concerns.

Dr. Cheryl Rosen, Director of Dermatology at BowTied Life says that turmeric is one of the most widely studied natural remedies, with research showing it can help treat skin inflammation caused by eczema, psoriasis and acne.

She also agrees that curcuminoids are responsible for turmeric's healing properties because "they're able to reduce pro-inflammatory molecules in our bodies" while increasing antioxidant levels."This spice is definitely worth trying if you have any inflammatory issues," says Rosen.

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Now that you know the many skin and health benefits turmeric and its component Curcumin can have, it's time to think about adding it to your own diet.

Dietitian and Wellness Professional Holli Rovenger suggests adding it to "a variety of foods" such as scrambled eggs, omelettes, frittatas, soups, casseroles, vegetables and even in smoothies.

The possibilities are truly endless!

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Judge orders Utahn to stop touting silver products as COVID-19 cure – KSL.com

Posted on May 1, 2020 by Danzig

SALT LAKE CITY A Cedar Hills man who prosecutors say has been fraudulently marketing silver products as a cure for the new coronavirus, has been ordered by a federal judge to stop selling those items.

On Wednesday, U.S. District Judge David Barlow issued a temporary restraining order against Gordon Pedersen, 60, and his companies, My Doctor Suggests LLC and GP Silver LLC. The injunction comes on the heels of a civil complaint filed Monday in Salt Lake City against Pedersen by U.S. Attorney for Utah John Huber.

The civil complaint alleges that the defendants are fraudulently promoting and selling various silver products for the treatment and prevention of COVID-19, according to a statement from Hubers office. The defendants have made a wide variety of false and misleading claims touting silver products as a preventative for COVID-19, including that having silver in the bloodstream will usher any coronavirus out of the body and that it has been proven that alkaline structured silver will destroy all forms of viruses, (and) it will protect people from the coronavirus.

Pedersen and his companies have promoted silver products as a treatment for various diseases, including arthritis, diabetes, influenza and pneumonia since about 2014, the civil complaint states. These items are marketed under various names such as Silver Solution, Silver Gel, Silver Soap and Silver Lozenge.

In early 2020, Pedersen and My Doctor Suggests started contending that the silver products also cured COVID-19, according to court documents.

Gordon Pedersen falsely claims that My Doctor Suggests silver products can destroy coronavirus, and remove it from the body, assuring the user will never get COVID-19, the complaint states.

In his online sales pitches, Pedersen refers to himself as a doctor and often gives his sales pitch in a white coat with a stethoscope around his shoulders, creating the appearance of a treating physician, even though ... Pedersen does not hold a doctor of medicine degree, and is not licensed as a medical provider in the state of Utah, the complaint alleges.

According to the Silver Health Institute website: Dr. Pedersen holds four doctors degrees. He has a doctorate of naturopathic medicine. He has a Ph.D. from the toxicology program at Utah State University, where he also has Ph.D. degrees in immunology and biology. He is board certified in anti-aging and regenerative medicine and also holds a masters degree in cardiac rehabilitation and wellness.

Defendants are creating a false sense of security that may cause consumers to avoid conventional medical treatment and to ignore travel restrictions and social distancing that slow the spread of COVID-19.Court documents

In one of his YouTube videos promoting a silver hand sanitizer, Pedersen says he is going to go out and shake hands with people, doctors, patients, people who are infected possibly with the flu ... and Im going to have a confidence level that I have protection, court documents state.

In a podcast interview in March, Pedersen claimed, If you have the silver in you, when the virus arrives, the silver can isolate and eliminate that virus, the complaint states. In the same podcast, Pedersen said he could freely travel and was even going on a cruise ship, but was confident he would not catch COVID-19 because of his products.

Prosecutors noted in court documents that the list prices on the My Doctor Suggests website range up to $299.95 for a gallon of the silver solution, a mix of water, sodium bicarbonate commonly known as baking soda and extract from silver wire the companys self-described flagship product.

Prosecutors further noted, There is no recognized cure for COVID-19, and no drug product has been proven safe and effective for the prevention, treatment or cure of COVID-19.

Even Pedersen knows silver products are not a proven cure or treatment for COVID-19, the complaint states. They are also aware that they cannot legally promote My Doctor Suggests silver products for the prevention and/or treatment of COVID-19, and distribute them in interstate commerce. Indeed, defendant Pedersen has stated that, We are not a cure for the coronavirus there is none, and acknowledged that he does not actually know whether the products kill coronavirus.

Prosecutors described Pedersens actions as reckless and harmful to consumers, the complaint says.

A federal court also froze all of Pedersens and his companies assets on Wednesday.

Even in a time of great uncertainty, there are at least two unchanging realities. There are those who would unlawfully exploit our vulnerabilities, and there are those who will hold such parties accountable, Huber said in a prepared statement. COVID-19 is a dangerous disease, and American consumers must have accurate and reliable information as they make important health decisions.

In issuing the restraining orders, Barlow wrote, There is good cause to believe that immediate and irreparable harm will result from defendants ongoing violations unless they are forced to stop, and that any harm a temporary restraining may cause to Pedersens businesses is greatly outweighed by the threat to the health and safety of individuals relying on defendants products and the representations regarding those products and to the public generally.

A hearing on the preliminary injunction is scheduled for May 12. As of Wednesday afternoon, the My Doctor Suggests website was offline.

Back To The Gym: Get Fit And Stay Safe – Longevity LIVE

Posted on June 30, 2020 by Danzig

Across the world, gym lovers are looking forward to their gradual return to their facilities. In different countries, the stringent stay-at-home restrictions put in place to combat COVID-19 are slowly being lifted. Restaurants, parts of the travel industry, and yes, gyms, are in the process of reopening. But following all the global changes that came with the restrictions, eager gym goers will likely be returning to a setup that looks very different from what they remember.

Theres also a measure of uncertainty around whether it will, in fact, be safe to head back to the combination of spinning rooms, weight sections, and public bathrooms. And for good reason. After all, the gym tends to be a place where bacteria like to congregate. According to a study published in the National Library of Medicine, about 25% of surfaces tested in four different athletic training facilities (or gyms) featured a variety of germs. It included various pathogens, the flu virus, and other drug-resistant bacteria. On top of that, experts are warning of the coming of a second wave of coronavirus if restrictions are lifted too early. All in all, its safe to say that while you may be eagerly anticipating your next spin class, its best to approach the gym with caution.

In light of the lifting of restrictions for several public spaces, various medical professionals and organizations have released important safety advice regarding how to return to the gym. For your own safety and that of the surrounding people, its important to understand how to adapt to the new environment.

Depending on with whom your gym membership is, you will probably be receiving some of this information a while before the reopening of their doors. The Mayo Clinic recommends calling ahead and finding out whether they have implemented a limit on how many members are allowed at once. Make sure you are familiar with their guidelines on matters like social distancing. This way, you can follow them safely.

Also, check the following aspects with the gym staff:

If you used to attend group classes, ask about whether they will still be offered. If so, find out how many people will be allowed in a group so you can plan accordingly.

Its important that we realize there is a risk involved in going back to the gym. This is because much of the way we exercise has to do with touch, particularly if weights, rollers, mats, or stationary bikes are involved. Gym equipment can be difficult to clean properly, and this can increase your risk of getting infected. Implementing hygiene practices can help to reduce this, but its hard to eliminate completely.

Make sure your hands are clean before entering the gym. Try to avoid touching anything when you sign in, as this is where a lot of germs can collect. If your gym does not provide it for members, it may help to carry a disinfectant with you. That way, you can clean any equipment after youve used it. Use your own water bottle, and try to avoid the drinking fountain.

Its likely that your gym will have changed the setup so that users will be able to use the available equipment while remaining the recommended 6 feet (1.83 m) away from one another. Speaking to The New York Times, Dr. Deverick Anderson said that stationary bikes, treadmills, and elliptical machines can be taped off, removed from service, or moved apart to enable social distancing. Dr. Anderson is a professor of medicine and the director of the Duke Center for Antimicrobial Stewardship and Infection Prevention at Duke University Medical Center in Durham, N.C.

In the interest of keeping members a safe distance from one another, its important that your gym has good ventilation. When we exercise, heavy breathing produces lots of respiratory droplets. These can remain on the surfaces of the gym even after our session has ended. Dr. Blocken from the Eindhoven University of Technology in the Netherlands and KU Leuven in Belgium, recommends that the gym be well-ventilated. It should also preferably use a system that constantly refreshes the inside air with filtered air from outside. Otherwise, wide-open doors on both sides of the room should provide adequate ventilation.

The Mayo Clinic recommends that if you are at risk of illness, you wait before going back to the gym. Instead, opt for virtual classes if they are available, or make use of YouTube classes online. If you are showing any symptoms of the virus, self-isolate and get rest for at least two weeks before considering going to the gym again.

Considering youll probably need to book out a gym session, you need to structure your day so that you can optimize your fitness. Even with the limitations you might now be subject to. The benefits of working out on a physical and mental level are worth it. Click on this link to find out how you can get your best workout even when you dont feel like it.

May, G. 2020. Is it safe to go back to the gym? The New York Times. https://www.nytimes.com/2020/05/13/well/move/coronavirus-gym-safety.html

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Autopsy: Hoping To Solve Mysteries Of Coronavirus – Anti Aging News

Posted on July 8, 2020 by Danzig

As in the past with autopsy, it is hoped that what is being learned from the dead, may help the living. When Amy Rapkiewicz began the process to learn how bodies of those who lost their battles to this virus went awry, the pathologist found damage to the lungs, kidneys, and liver that was consistent with what doctors had been reporting for months, yet something was off.

Rapkiewicz directs autopsies at NYU Langone Health, and when she was taking on the grim and daunting tasks she noticed some organs had far too many of a special cell that is rarely found in the places where it was. Though she had never seen it before it seemed familiar, and after researching history books she found reference to a 1960s report on a patient with dengue fever.

Rapkiewicz learned that in dengue the virus appeared to destroy these cells which produces platelets and leads to uncontrolled bleeding, and this novel virus seems to be amplifying their effects to cause dangerous clotting. Of the parallels she says: Covid-19 and dengue sound really different, but the cells that are involved are similar.

Autopsies have been used as a valuable source of information and breakthroughs leading to understanding new diseases for many decades, with this outbreak the medical community is counting on them to do the same for COVID-19. Hospital systems are too busy trying to save lives to spend too much time trying to reveal the secrets of the dead, but the first large batch of reports involving patients ranging between the ages of 32-90 have been published. Investigations have confirmed early suggestions of the disease and refuted others, but they have also opened up new mysteries about this pathogen.

Consistent across several studies is the finding that this virus appears to attack the lungs most viciously, and the pathogen was also found in parts of the brain, liver, kidneys, spleen, gastrointestinal tract, and in the endothelial cells that line blood vessels. Also as was suspected there was widespread clotting found in many organs. But the brain and heart revealed surprising findings.

Its about what we are not seeing, said Mary Fowkes, an associate professor of pathology who is part of a team at Mount Sinai Health that has performed autopsies on 67 COVID-19 patients.

Fowkes was expecting to find the virus or inflammation or both in the brain given the reports about neurological symptoms related to this virus, but there was very little and all autopsy investigations found no evidence of myocarditis in the heart despite months of concern over suspected cardiac complications.

Pathologists found another unexpected finding, that of the oxygen deprivation of the brain and the formation of blood clots may start early on in the disease process; this could have implications for how those with this disease are treated and home and if they need to be hospitalized.

Autopsies can help to reconstruct the natural course of disease, but the process for such a new and highly infectious disease requires dedicated and meticulous work with the use of specialized tools to harvest organs to be put into a disinfecting solutions for several weeks before they can be studied to avoid sending the virus into the air. After this process each organ must be sectioned and small bits of tissue must be collected to study under different types of microscopes.

One of the first American investigations to be made public was that of a 44 year old man who was treated in LSU Health; Richard Vander Heide who has been performing autopsies since 1994 remembers discovering what was probably hundreds or thousands of microclots in the lungs. This was something that was unusual that he has never seen before, but as he moved to the next patient and the next he saw the same pattern. He was so shocked and alarmed that he shared a paper online before submitting to a journal to get this information out immediately to all doctors; and his findings have influenced many hospitals to give blood thinners to some COVID-19 patients, and it is now a common practice. Subsequently the final peer reviewed version has been published in the Lancet.

Other autopsies have reported similar findings of clotting, and more recently a study published in the Lancets eClinical Medicine reports abnormal clotting in the heart, kidney, liver, and lungs leading the authors to suggest that this may be a cause of the multiple organ failure in COVID-19 patients.

One of the frightening early reports was the number of hospitalized patients appearing to have myocarditis that could lead to sudden death. Classic myocarditis is typically easy to identify in autopsies, as it occurs when the body perceives tissues to be foreign and attacks it causing large dead zones in the heart, and muscle cells would be surrounded by infection fighting lymphocytes cells. However thus far in the autopsy samples taken the dead myocytes were not surrounded by lymphocytes, only very mild inflammation has been seen on the surface of the heart but nothing that looks like myocarditis, according to Fowkes from Mount Sinai.

Rapkiewicz of NYU Langone was shocked at the abundance in the heart of the rare megakaryocytes cells, these cells produce platelets that control clotting, and typically exist only in bone marrow and lungs. Taking samples from COVID-19 patients lungs she discovered that those cells were in abundance there as well. I could not remember a case before where we saw that, she said. It was remarkable they were in the heart.

From LSU Vander Heide has a more in-depth paper that is under review in a journal explains that when you look at a covid heart, you dont see what youd expect. According to him a few autopsies he performed were on patients that had gone into cardiac arrest in the hospital, but after examination the primary damage was found in the lungs not in the heart.

A host of neurological impairments are also being reported including excessive sleepiness, reduced ability to smell or taste, altered mental status stroke, seizures, and delirium. 84% of patients in France in ICUs are reported to have had neurological problems with one third being confused or disoriented at discharge. In the UK one report suggests that 57 of 126 patients with a new neurological or psychiatric diagnosis experienced a stroke due to a blood clot in the brain, with 39 having an altered mental state.

Isaac Solomon, a neuropathologist at Brigham and Womens Hospital in Boston has conducted autopsies taking slices of key areas of the cerebral cortex, thalamus, basal ganglia, and others to investigate where this virus may be embedding itself into the brain. Each slice is divided into three dimensional grids, and 10 sections were taken from each to be studied. Solomon was only able to find snippets of the virus in some areas, and it was unclear whether they were dead remnants or active virus when the patient died; only small pockets of inflammation were found, but large swaths of damage due to oxygen deprivation was found. According to Solomon the pattern was eerily similar regardless of the patient suddenly dying or being in long term intensive care.

Findings underscore the importance of getting supplementary oxygen to patients quickly to prevent irreversible damage. Solomon has published a report in the New England Journal of Medicine, in it he suggests the findings suggest that the damage had been happening over a longer period of time, making him wonder about the effect on those who had been less ill.

The big lingering question is what happens to people who survive covid, said Solomon. Is there a lingering effect on the brain?

A Mount Sinai Health team took samples from brains, who were also shocked at the lack of virus and inflammation discovered, but they noted the widespread presence of tiny clots as being striking.

If you have one blood clot in the brain, we see that all the time. But what were seeing is, some patients are having multiple strokes in blood vessels that are in two or even three different territories, Fowkes said.

Rapkiewicz believes that it is too early to know whether the newest batch of autopsy reports can be translated into changes in treatment, but the information has revealed new paths to explore. One of her first calls was to Jeffrey Berger who is a cardiac specialist at NYU and runs a NIH funded lab focusing on platelets after she noticed the unusual platelet producing cells.

According to Berger the autopsies suggest that antiplatelet medications along with blood thinners may be useful for some of the symptoms of COVID-19, and he is pivoting a clinical trial to investigate the optimal doses while examining the effectiveness of such treatment.

Its only one piece of a very big puzzle, and we have a lot more to learn, said Berger. But if we can prevent significant complications and if more patients can survive the infection, that changes everything.

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Autopsy: Hoping To Solve Mysteries Of Coronavirus - Anti Aging News

How Old Is Your Dog in Human Years? Scientists Develop Better Method than ‘Multiply by 7’ – UC San Diego Health

Posted on July 8, 2020 by Danzig

If theres one myth that has persisted through the years without much evidence, its this: multiply your dogs age by seven to calculate how old they are in human years. In other words, the old adage says, a four-year-old dog is similar in physiological age to a 28-year-old person.

But a new study by researchers at University of California San Diego School of Medicine throws that out the window. Instead, they created a formula that more accurately compares the ages of humans and dogs. The formula is based on the changing patterns of methyl groups in dog and human genomes how many of these chemical tags and where theyre located as they age. Since the two species dont age at the same rate over their lifespans, it turns out its not a perfectly linear comparison, as the 1:7 years rule-of-thumb would suggest.

To calculate your dogs age in human years based on epigenetics, find the dogs age along the bottom axis and trace your finger straight up until you reach the red curve. Then trace your finger straight over to the left to find the corresponding human age. Credit: Cell Press

The new methylation-based formula, published July 2 in Cell Systems, is the first that is transferrable across species. More than just a parlor trick, the researchers say it may provide a useful tool for veterinarians, and for evaluating anti-aging interventions.

There are a lot of anti-aging products out there these days with wildly varying degrees of scientific support, said senior author Trey Ideker, PhD, professor at UC San Diego School of Medicine and Moores Cancer Center. But how do you know if a product will truly extend your life without waiting 40 years or so? What if you could instead measure your age-associated methylation patterns before, during and after the intervention to see if its doing anything? Ideker led the study with first author Tina Wang, PhD, who was a graduate student in Idekers lab at the time.

The formula provides a new epigenetic clock, a method for determining the age of a cell, tissue or organism based on a readout of its epigenetics chemical modifications like methylation, which influence which genes are off or on without altering the inherited genetic sequence itself.

Epigenetic changes provide scientists with clues to a genomes age, Ideker said much like wrinkles on a persons face provide clues to their age.

Ideker and others have previously published epigenetic clocks for humans, but they are limited in that they may only be accurate for the specific individuals on whom the formulas were developed. They dont translate to other species, perhaps not even to other people.

Ideker said it was Wang who first brought the dog idea to him.

We always look at humans, but humans are kind of boring, he said. So she convinced me we should study dog aging in a comparative way.

To do that, Ideker and Wang collaborated with dog genetics experts Danika Bannasch, DVM, PhD, professor of population health and reproduction at UC Davis School of Veterinary Medicine, and Elaine Ostrander, PhD, chief of the Cancer Genetics and Comparative Genomics Branch at the National Human Genome Research Institute, part of the National Institutes of Health. Bannasch provided blood samples from 105 Labrador retrievers. As the first to sequence the dog genome, Ostrander provided valuable input on analyzing it.

First author Tina Wang, PhD, (right) with her husband, Brandon, and their dog, Belli, who inspired the study. Photo courtesy of Tina Wang.

Dogs are an interesting animal to study, Ideker said. Given how closely they live with us, perhaps more than any other animal, a dogs environmental and chemical exposures are very similar to humans, and they receive nearly the same levels of health care. Its also important that we better understand their aging process, he said, as veterinarians frequently use the old 1:7 years ratio to determine a dogs age and use that information to guide diagnostic and treatment decisions.

What emerged from the study is a graph that can be used to match up the age of your dog with the comparable human age. The comparison is not a 1:7 ratio over time. Especially when dogs are young, they age rapidly compared to humans. A one-year-old dog is similar to a 30-year-old human. A four-year-old dog is similar to a 52-year-old human. Then by seven years old, dog aging slows.

This makes sense when you think about it after all, a nine-month-old dog can have puppies, so we already knew that the 1:7 ratio wasnt an accurate measure of age, Ideker said.

According to Ideker, one limitation of the new epigenetic clock is that it was developed using a single breed of dog, and some dog breeds are known to live longer than others. More research will be needed, but since its accurate for humans and mice as well as Labrador retrievers, he predicts the clock will apply to all dog breeds.

Next, the researchers plan to test other dog breeds, determine if the results hold up using saliva samples, and test mouse models to see what happens to their epigenetic markers when you try to prolong their lives with a variety of interventions.

Meanwhile, Ideker, like many other dog owners, is looking at his own canine companion a little differently now.

I have a six-year-old dog she still runs with me, but Im now realizing that shes not as young as I thought she was, Ideker said.

Co-authors of the study also include: Jianzhu Ma, Samson Fong, Katherine Licon, Brian Tsui, Jason F. Kreisberg, UC San Diego; Andrew N. Hogan, National Human Genome Research Institute, National Institutes of Health; Peter D. Adams, Sanford Burnham Prebys Medical Discovery Institute; and Anne-Ruxandra Carvunis, University of Pittsburgh School of Medicine.

Funding for this research came, in part, from the National Institutes of Health (grants ES014811, GM108865, GM008666, AG031862 and DE022532; NHGRI intramural program), California Institute for Regenerative Medicine (CIRM), and Maxine Adler Endowed Chair Funds.

An earlier version of this paper was shared as a preprint on BioRxiv on November 19, 2019, prior to peer-review and publication in Cell Systems.

Disclosure: Trey Ideker is co-founder of Data4Cure, Inc., is on the Scientific Advisory Board, and has an equity interest. He is also on the Scientific Advisory Board of Ideaya BioSciences, Inc., has an equity interest, and receives sponsored research funding. The terms of these arrangements have been reviewed and approved by the University of California San Diego in accordance with its conflict of interest policies.

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How Old Is Your Dog in Human Years? Scientists Develop Better Method than 'Multiply by 7' - UC San Diego Health

MD Ageless Solution CEO Yakelin Sosa shares Benefits of Non-Surgical Facelift and Neck lifting – Life Pulse Health

Posted on June 4, 2020 by Danzig

United States, Florida, Miami 06-02-2020 (PRDistribution.com) MD Ageless Solutions is a multidisciplinary and a revolutionary medical spa. We specialize in regenerative and aesthetic medicine by using the newest and most innovative technologies.

We provide a variety of skin care treatments using the best and most efficient aesthetic treatments available. We use the latest scientific technologies and applications in treating skin problems and disorders. We provide the most advanced and painless skin treatments that you can only imagine.

We dont only have the best technologies, we also have highly experienced skincare professionals that work together to provide the best skin care treatments to all our clients. Our aim and goal is to provide and promote beauty and total skin wellness to our clients. We provide the best skin care services that you can find in Miami and around Florida.

Who is Yakelin Sosa

Dr. Yakelin Sosa, MD is a reputable and highly trained Anesthesiologist. She is certified in both aesthetics and advanced aesthetic treatments for aging skin and face. She is the CEO of MD Ageless Solutions Miami, Florida.

Dr. Sosa attended the University Of Puerto Rico School Of Medicine where she graduated Magna Cum Laude with her medical degree. She then went further to complete a 2 year residency training in Internal Medicine at Baylor College of Medicine in Texas.

Dr. Sosa has been in the field of aesthetics for over thirteen years and she is certified by the American Academy of Anti-aging Medicine. She has the leading training facility for aesthetic treatments in South Florida.

Dr. Sosa does not only have an excellent background in skincare treatments, she is also highly skilled and experienced in her field. She is very hardworking and continually incorporates the newest technologies into her practice. She is affiliated with several reputable and well-known medical organizations and bodies.

Benefits of Non-surgical Facelift and Neck lift

Nonsurgical facelift and neck lift are minimally invasive nonsurgical procedures used to rejuvenate and improve the appearance of your face and neck. The techniques used for nonsurgical facelift and neck lift do not require incisions, use of general anesthesia, or long stay at the hospital or clinic. There is no downtime with this technique and the side effects are very minimal. Nonsurgical facelift and neck lift techniques include the use of dermal fillers, botox and fat injections to rejuvenate, lift and improve the appearance of the face and neck.

Nonsurgical facelift and neck lift provides several benefits more than the surgical facelift and neck lift procedures. Instead of going through the rigorous, invasive and painful processes of surgical facelift and neck lift, it is best you opt for a simpler, noninvasive and painless facelift and neck lift procedure.

The benefits of nonsurgical facelift and neck lift include:

There are no downtime or recovery times Nonsurgical facelift and neck lift procedure require little or no downtime. After the treatment, you dont need to stay in the hospital for days because you can go back home immediately after the treatment. Also, you recover very fast after undergoing the treatment. You dont need to stay at home for weeks or months recovering from a nonsurgical treatment, unlike the surgical procedure whereby you may need to speed weeks or even months at home during recovery. You can still keep your appointments and continue your work after undergoing a nonsurgical facelift and face lift procedure.

It produces natural-looking and lasting results Nonsurgical facelift procedure involves the use of fillers, Botox and your own fat. The procedure does not involve incisions, unlike the surgical procedure that involves incision. Nonsurgical procedures use chemical substances that are found in your body to rejuvenate and improve the appearance of your facial skin and neck. It provides a more natural looking facial appearance than the surgical procedure. Also, there are no scars after undergoing a nonsurgical procedure.

It does not require the use of general anesthesia Nonsurgical facelift and neck lift treatments do not require the use of general anesthesia. This is a better option for people that are allergic to the substances used in producing the anesthesia. If you are allergic to any of the substances used in producing anesthesia, nonsurgical treatment is best for you.

The treatments are not as expensive as surgical procedures Nonsurgical facelift and neck lift procedure is relatively cheaper than surgical facelift and neck lift procedure. People who are on a budget can easily afford the nonsurgical facelift and neck lift treatment. Hence, it is better to opt for the nonsurgical option if you want to save costs.

It is faster Nonsurgical facelift procedures take a shorter time to be completed, unlike the surgical facelift and neck lift procedures. Surgical procedures require administration of general anesthetics, large incisions, and other things that take up a lot of time. You cannot go back to your job or continue with your activities for the day after undergoing surgical facelift and neck lift procedures but you can go back to your job or continue your activities for the day after undergoing nonsurgical facelift and neck lift procedures.

Patients experience little discomfort You dont experience pain or serious discomfort during or after nonsurgical facelift and neck lift procedures. The procedure doesnt involve large incisions; hence you only feel little or no discomfort. If you have a low threshold for pain, it is best you opt for nonsurgical facelift and neck lift treatment instead of the surgical procedure.

It helps to enhance facial looks and eliminate wrinkles Nonsurgical facelift and neck lift treatment helps to enhance your facial and neck appearance with ease. You can experience almost immediate results after undergoing nonsurgical facelift and neck lift treatment.

Fewer risks Surgical facelift and neck lift procedures involve more risks and complications but there are little or minor complications with the nonsurgical facelift and neck lift procedure. The risks and complications that you may experience during and after undergoing a surgical facelift and neck lift procedure far outweigh the risk of nonsurgical facelift and neck lift procedure. It is best to opt for a nonsurgical facelift and neck lift treatment if you dont want to experience serious side effects or complications.

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Oxytocin: Benefits & How To Boost The Love Hormone – Longevity LIVE

Posted on June 15, 2020 by Danzig

You may know it as the love hormone, but theres more to oxytocin than the feel-good emotions it creates when you give someone a long and warm hug.

Oxytocin is an endorphin that helps to regulate social interaction, playing a pivotal role in bonding. Now while it is commonly referred to as the love hormone, it is anything but a love potion. The brain chemical wont make you instantly fall in love with someone. Rather, it will boost feelings of love, care as well as trust towards someone you already care for. That said, strengthening your social circles isnt all that oxytocin is good for.

According to research, oxytocin can help to improve relationships by enforcing sociable behavior. In fact, one study found that the love hormone not only helps to increase trust and generosity, but it also reduces the fear of betrayal. Additionally, an earlier studyfound that oxytocin helped topromote fidelity within monogamous relationships.

Oxytocin may be the boost that your sex life needs. According to German researchers, after being treated with oxytocin, female partners not only experienced improved sexual response but their male partners also experienced an improvement in their erectile function.

Neuroinflammation refers to inflammation of nervous tissue, most notably of the neurons in the developing brain.

That said, a recent studypublished in the Frontiers in Neurology journal suggests that oxytocin may play a role in the protection of the fetal and infant brain, particularly during gestation, birth trauma, as well as early growth.

While there have yet to be any human trials, oxytocin is currently being investigated for its potential role in drug addiction treatment. A 2017 study found that the love hormone helped reduce addictive behavior in animals.

During childbirth, oxytocin not only strengthens labor contractions but it also facilitates the production of prostaglandins, which are chemicals that help cause the cervix to dilate and contractions to occur. The brain chemical also helps to control bleeding after childbirth.

When a mother breastfeeds her newborn, the act stimulates the release of oxytocin and this helps to foster a strong loving and caring bond between mother and child.

Oxytocin may be the secret to anti-aging.

According to a study published in the Nature Communications journal, high levels of oxytocin may help to protect againstaccelerated signs of aging and it may even encourage better regeneration of aged tissue stem cells.

In a sense, yes. Oxytocin helps to strengthen the bond you have with those closest to you. Now while this is a good thing, it can also make you more overprotective and willing to do anything for them including lie or bend ethical rules. In fact, one study found thatthosewho received oxytocin were twice as likely to lie than usual.

Additionally, too much oxytocin can also make you less trustworthy of people outside your inner circle, and in the w10 orst cases, it can fuel prejudice, envy, aggression, as well as xenophobia (1).

According to research, autism, schizophrenia, depression, as well as anxiety disorders can each cause an oxytocin deficiency.

Additionally, high-stress levels can also cause a deficiency. Studies have found that as levels of the stress hormone cortisol go up, oxytocin levels go down. (2)

According to research, vitamin D helps to activate the brain hormones serotonin and oxytocin.

Now ideally, you should get your vitamin Dnaturally from the sunbut it can be hard to do so, especially in a pandemic. That said, you can either take avitamin D supplementor opt for vitamin D rich foods such as salmon and fortified vitamin D foods.

Vitamin C helps to stimulate the production of oxytocin. Now not only should you increase your vitamin C intaketo raise your oxytocin levels, but it can also help to strengthenyour immune system which we all need to do right now.

In addition to supplements, vitamin C can also be found in citrus fruits, tomatoes, cauliflower, Brussels sprouts, broccoli, as well as cabbage.

Magnesiumis a vital mineral thats involved in over300 biochemical reactions in your body, which includes increasing the action of oxytocin.

Up your magnesiumlevels by increasing your intake of spinach, chard, pumpkin seeds, almonds, avocado, dark chocolate, as well as bananas.

Chamomile is a great calming tea, so much so that it helps to increase oxytocin levels all while lowering levels of cortisol(3).

Now, this may be a little hard to do with the social distancing regulations. However, if youre on lockdown with your family, and theyve each been tested, then theres no reason as to why you cant give them a long hug.

In addition to increasing your oxytocin levels, a10-second hug every day can also help to boost your immune systemand improve heart health.

Daily meditation is great for your health and mood. That said, loving-kindness meditation (also known as metta) has been found to increase your love-hormone levels as well as increase your sense of connection as well as strengthen your relationships with others.

Animals are our best friends and if you have any pets, playing with them can help to lower your blood pressure as well as increase your oxytocin levels.

In fact, one studyfound that oxytocin levels increased in both humans and dogs after just five minutes of petting.

Music is incredibly healing and it can do wonders for your oxytocin levels.

For instance, one study found that after listening to music for 30 minutes a day after open-heart surgery, patients had significantly higher levels of oxytocin compared to those who were simply told to rest in bed.

And its not just listening to the music that can help as singing along can also increase oxytocin levels. Its no wonder mothers are always singing lullabies to their newborns.

A little hard to do with the COVID-19 regulations, but thats nothing the magic of technology cant fix.

Calling, texting or checking in with your friends and family using various apps can help toincrease oxytocin levels.In fact, researchhas found thatyour brain releases more oxytocin during social contact and social bonding, and this can help to speed up healing from disease.

If you want to do some good, as well as boost your own oxytocin, then volunteering is a great way to go.

A study published in the Hormones and Behavior journal found that volunteering not only reduces your stress levels but it also increases oxytocin levels.

With the state of the world, there are plenty of ways you can do good from the comfort of your own home. Be it signing petitions in relation to social justice or donating to COVID-19 relief funds theres plenty of good you can do.

There are at least 20 different types of endorphins and each has a different function.That said, there are plenty of ways one cannaturally boost their levels of endorphins.

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Oxytocin: Benefits & How To Boost The Love Hormone - Longevity LIVE

Carolyn Matzinger, MD Provides the Most Comprehensive Solution to Combat Fear and Effects of Covid-19 – Nevada Business Magazine

Posted on May 15, 2020 by Danzig

Las Vegas, NV Carolyn Matzinger, MD of Matzinger Institute of Healing (MIH), is an Internal Medicine Specialist, and leader in Cellular and Membrane/Metabolic Medicine. She has successfully treated 20,000+ patients, and is recognized for proven results in restoring total body health and improving the quality of life for patients diagnosed with various medical conditions, including: Lyme disease, Mold Toxicity, Mast Cell Activation Syndrome, Neurodegenerative disorders, Dementia, Diabetes, Cancer, Autism, Seizures and more. Facts affirm the importance of a strong immune system. During this challenging time, she is encouraging people, now more than ever, to strengthen and maintain a healthy immune system as the best defense against the effects of the Covid-19 virus.

To help boost the health of Southern Nevada residents, Dr. Matzinger has developedtheMIHImmune Support Plan, monthly treatments (for 3 months) that consist of intravenous vitamin infusions (Myers Cocktails, Vitamin C, Vitamin B12 injections) and Infrared Saunas. These treatmentsoptimize the immune system and combat a myriad of opportunistic conditions caused from a weakened immune system. Dr. Matzinger extends special discounts and incentives MIH Immune Support Plan to our Veterans, First Responders, and 55+ Communities.

With the World Health Organization declaring the Covid-19 virus a pandemic combined with the Global lock-down and social distancing mandates, the spread of the virus will slow down. However, health, political, and economic uncertainties may continue rise of fear, anxiety and stress.Dr. Matzinger stated,We must shift our focusfrom fear of uncertainties tofacts and productivity, she adds,We mustremain calm. It is a fact that increased stress and anxiety increase cortisol levels, which then leads to heightened inflammation and a weakened immune system.Stayingwell is the number one priority. Stronger than a cure are prevention and total body health (vitamin infusions, Infrared Saunas, healthy eating, appropriate supplements, Medical Lipid Colon Cleanses, regular exercise,sufficient hydration,love and laughter).

The fact remains that people with weakened immune systems are more vulnerable to the severe effects of the virus.; those over the age of 55, post- Cancer patients and individuals with pre-existing medical conditions (such as Asthma, Diabetes, Heart Disease, etc.).Thereported cases and fatalities of the virus may increase before we witness a rapid decline, andindeed a vaccine will become available.Yet, even the swiftest efforts to develop a safe vaccine, perform proper clinical trials, and manufacture an adequate supply will take at least 10 to 18 months. Nonetheless,individual immune health is important to fight off a virus, to assure inactivation of the virus in a vaccine, along with allowing the body its ability to weaken the side-effects of a vaccine.

AsDr. Matzinger leads efforts tokeep our community healthy, build solutions, and help get our lives back, it is important to recognize the following key factors that makes her practice and the MIH Immune Support Plan exceptional: MIH Immune Support Plan and all treatments are administered by a Medical Doctor; Matzinger Institute of Healing offers the most effective customized treatment plans, based on extensive nutritional and diagnostic studies.

Schedule an appointment by calling702-778-6100. MIH is located at1740 W. Horizon Ridge PKWY, Henderson, NV 89012

For more information about #MIH, visit:www.mih.vegas

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Shawn Willis

5AM Global

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About Matzinger Institute of Healing

Matzinger Institute of Healing (MIH) is a medical center with the principle idea to recreate total health by improving the immune system and decreasing inflammation. The facility utilizes the technology of Epigenetics and state-of-the-art membrane treatments with an emphasis on the gut-brain connection, and is recognized for proven results in restoring total body health and improving the quality of life for patients diagnosed with various medical conditions, including: Lyme disease, Mold Toxicity, Mast Cell Activation Syndrome, Neurodegenerative disorders, Dementia, Diabetes, Cancer, Autism, Seizures and more. All treatments are customized to each patients specific needs, and are administered by a medical doctor.

MIH is led by Carolyn Matzinger, MD, an Internal Medicine Specialist and leader in Cellular and Membrane/Metabolic Medicine, who began her medical career over 30 years ago. She has successfully treated 20,000+ patients, and is currently licensed in five states including; Nevada, California, Ohio, Idaho and Montana. Dr. Matzinger studied Lipid Therapy in Germany, and is one of the initial three Medical Doctors in the world who provides the Intensive Lipid Therapy treatments. She co-authored Audacious Aging with other professionals such as Deepak Chopra, and Andrew Weil, which won a silver medal in the Independent Publisher book awards. She is a Board Certified Physician and Diplomate of the American Board of Anti-Aging Medicine.

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Carolyn Matzinger, MD Provides the Most Comprehensive Solution to Combat Fear and Effects of Covid-19 - Nevada Business Magazine

Virtual Event June 1 Explores Aging, Heart Disease and COVID-19 – Florida Tech Now

Posted on May 29, 2020 by Danzig

Johns Hopkins Professor Explains New Research on Protecting the Most Vulnerable

MELBOURNE, FLA. A medical doctor and researcher at Johns Hopkins University who leads human cardiovascular studies at the Laboratory of Cardiovascular Science at National Institutes of Healths National Institute on Aging will explore the intersection of aging, heart disease and COVID-19 during a free virtual workshop from 1-2:30 p.m. Monday, June 1, organized and hosted by Florida Tech.

Dr. Majd AlGhatrif will discuss why older adults with underlying cardiovascular disease are experiencing increased disease severity and higher mortality rates from COVID-19. These possible connections were highlighted in an April article in the Journal of the American Medical Associations JAMA Cardiology byAlGhatrif and Edward G. Lakatta, both of the Laboratory of Cardiovascular Science in NIAs Intramural Research Program, and Oscar Cingolani of the Johns Hopkins School of Medicine.

In their article, the authors propose that using blockers for hormones called angiotensin that affect blood pressure may prevent severe COVID-19, particularly in older adults with low baseline levels of a key anti-inflammatory factor called angiotensin converting enzyme 2, or ACE2. However, this hypothesis needs to be tested in clinical trials with people who have COVID-19 to determine the safety and efficacy of these medications in reducing the risk of developing severe lung disease, they note.

In addition to AlGhatrifs presentation and question-and-answer segment, the event will feature short presentations about several efforts undertaken at Florida Tech in response to the pandemic. Those scheduled to present are:

Marco Carvalho, Ph.D., Florida Techs executive vice president for academics, will offer opening remarks.

To participate online, visit https://fit.zoom.us/j/95454967579.

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Virtual Event June 1 Explores Aging, Heart Disease and COVID-19 - Florida Tech Now

Medical Device Testing Services Market Break Down By Leading Companies, Countries, Applications, Challenges, Opportunities And Forecast 2020-2026 -…

Posted on June 4, 2020 by Danzig

Trusted Business Insights answers what are the scenarios for growth and recovery and whether there will be any lasting structural impact from the unfolding crisis for the Medical Device Testing Services market.

Trusted Business Insights presents an updated and Latest Study on Medical Device Testing Services Market 2019-2026. The report contains market predictions related to market size, revenue, production, CAGR, Consumption, gross margin, price, and other substantial factors. While emphasizing the key driving and restraining forces for this market, the report also offers a complete study of the future trends and developments of the market.The report further elaborates on the micro and macroeconomic aspects including the socio-political landscape that is anticipated to shape the demand of the Medical Device Testing Services market during the forecast period (2019-2029).It also examines the role of the leading market players involved in the industry including their corporate overview, financial summary, and SWOT analysis.

Get Sample Copy of this Report @ Medical Device Testing Services Market Size, Market Research and Industry Forecast Report, 2027 (Includes Business Impact of COVID-19)

Industry Insights, Market Size, CAGR, High-Level Analysis: Medical Device Testing Services Market

The global medical device testing services market size was estimated at 6.9 billion in 2019 and is anticipated to expand at a CAGR of 9.4 % over the forecast period. Increasing complexity in product design, coupled with stringent regulatory norms, is anticipated to drive the market. All medical devices have a unique set of testing requirements enforced by various regulatory bodies such as the U.S. Food and Drug Administration and the China Food and Drug Administration.

Growing trend of outsourcing medical device testing services is also projected to drive the market. Emergence of personalized medicine, drug device combination, Artificial Intelligence (AI), and wearables, coupled with increasing focus on real-time patient monitoring, has resulted in a complex medical devices ecosystem. To match these parameters, devices now have to undergo stringent testing in accelerated conditions to obtain marketing approval. Conducting these tests in-house requires a lot of time, cost, and labor and this is projected to augment the demand for outsourcing medical device testing services.Ongoing technological development in the medical device industry is also likely to have a positive impact on the demand for testing services during the forecast period. Advancement in the development and standardization of novel in-vitro test methods, particularly for sensitization, cytotoxicity, and irritation, is also likely to propel the market growth. These are some of the most basic tests required for all medical devices.A rising number of companies are contributing to the growth of this market. Structurally, the global medical device industry is led by a handful of major players and a large number of small- and medium-sized enterprises (SMEs). Escalating demand from SMEs, which lack in-house capabilities, will support the market.Services InsightsThe medical device testing services market is segmented based on service into biocompatibility tests, chemistry test, microbiology and sterility testing, and package validation. Microbiology and sterility testing services include bio-burden determination, Pyrogen and endotoxin testing, sterility test and validation, and anti-microbial activity testing.This segment held the dominant share in 2019 and is likely to retain its lead throughout the forecast period.Biocompatibility testing services for medical devices account for a significant share in the market owing to the lower cost of these tests. Development of novel in-vitro methods is expected to replace some of the older in-vivo tests, thereby reducing the cost of biocompatibility tests. Chemistry testing services are a great tool to identify which biocompatibility tests should be carried out and this segment is expected to witness the fastest growth during the forecast period.Phase InsightsOn the basis of phase, the market is segmented into preclinical and clinical. Medical device testing during the preclinical phase includes testing of antimicrobial wound dressings and medical coatings. The preclinical segment accounted for the largest market share in 2019. A significant rise in preclinical spending on pharmaceutical and medical device testing is the primary factor contributing to the growth of this segment.

Medical device testing services during the clinical trial phase are also expected to witness significant growth over the next few years. The device development process comprises numerous phases, which includes cleaning validation, sterilization testing and validation, package and shipping testing, and shelf life and accelerated aging test.

Regional Insights of Medical Device Testing Services Market

Asia Pacific dominated the market in 2019 and is expected to retain its lead throughout the forecast period. This can be attributed to increasing R&D activities in this region and growing adoption of new technologies in clinical trials. Rising need for long-term therapy by patients is also driving the regional market. Contract research organizations (CROs) are investing heavily in this region due to lower costs and easy availability of skilled labor.North America held the second-largest share in 2019 and is expected to witness rapid growth during the forecast period. Increasing complexity in product designing and growing efforts toward cost-cutting are expected to be the major factors driving this regional market.

Market Share Insights of Medical Device Testing Services Market

The global market is highly competitive. Some of the key players operating in the market are Toxikon, Inc.; SGS S.A.; Eurofins Scientific, LLC; Intertek Group plc; WuXi AppTec Group; Pace Analytical Services; North American Science Associates, Inc.; Sterigenics International LLC; Charles River Laboratories International, Inc.; and American Preclinical Services LLC.Rapid adoption of advanced healthcare technology for improved healthcare is a key parameter affecting the competitive nature of the vendor landscape. Major players undertake mergers and acquisitions along with launch of new services in order to expand their share in the market and diversify their product portfolio.

Segmentations, Sub Segmentations, CAGR, & High-Level Analysis overview of Medical Device Testing Services Market Research ReportThis report forecasts revenue growth at global, regional, and country levels and provides an analysis on latest industry trends in each of the sub-segments from 2019 to 2030. For the purpose of this study, this market research report has segmented the global medical device testing services market report on the basis of service, phase, and region:

Service Outlook (Revenue, USD Million, 2019 2030)

Biocompatibility Tests

Chemistry Test

Microbiology & Sterility Testing

Bio-Burden Determination

Pyrogen and Endotoxin Testing

Sterility Test and Validation

Anti-microbial Activity Testing

Others

Package Validation

Phase Outlook (Revenue, USD Million, 2019 2030)

Preclinical

Antimicrobial Wound Dressings

Medical Coatings

Others

Clinical

Quick Read Table of Contents of this Report @ Medical Device Testing Services Market Size, Market Research and Industry Forecast Report, 2027 (Includes Business Impact of COVID-19)

Trusted Business InsightsShelly ArnoldMedia & Marketing ExecutiveEmail Me For Any ClarificationsConnect on LinkedInClick to follow Trusted Business Insights LinkedIn for Market Data and Updates.US: +1 646 568 9797UK: +44 330 808 0580

How To Make Your Face Mask Your Breathing Friend And Filter – Longevity LIVE

Posted on May 12, 2020 by Danzig

Why might I get symptoms while wearing a face mask?

The ideal mask will allow for the easy flow of air (breathable) but will prevent the spread of droplets through it (impermeable).

If your mask does not allow air to flow through it, this could have negative effects on your health and well-being.

Typically, when we are worried or anxious, adrenaline causes us to take faster and shallower breaths. This leads to lower levels of carbon dioxide in the blood which in turn can cause dizziness, fatigue, headaches, chest pain, breathlessness, numbness and tingling, a feeling of disorientation or confusion, and increased emotionality.

If your mask is adequately breathable, it is more likely that symptoms experienced are related to your own breathing rather than the mask itself.

Medical grade masks are specifically designed to offer high level protection (impermeability) and adequateoxygenation (breathability) while undertaking highly skilled and high-risk tasks. While the public does not require medical grade masks, manufactured and home-made masks should offer the same level of breathability and reasonable impermeability.

A recent study done in Illinois demonstrated that a mask made with double layered T-shirt material (cotton or cotton/polyester blends) balances the best breathability with a 98% impermeability to droplet spread which performs equally to medical masks.

The only difference is that household materials will retain droplets rather than repel them, so it is important to hot wash (or dispose of) them after each use.

Breathing through the nose provides the benefit of the air being moistened and filtered. Nasal breathing also produces Nitric Oxide which kills viruses and bacteria.

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How To Make Your Face Mask Your Breathing Friend And Filter - Longevity LIVE

Voyageur Secures Exclusive Rights To One Of The Worlds Rarest Pharmaceutical Minerals, Creating A New Era In Carbon Based Drug Development -…

Posted on May 12, 2020 by Danzig

CALGARY, Alberta, May 11, 2020 (GLOBE NEWSWIRE) -- Voyageur Pharmaceuticals Ltd. (TSX.V:VM) (USA:VYYRF) (the Company or Voyageur) is pleased to announce it has signed an LOI with an established international mining company (the Counterparty) that has developed a low cost method to extract the natural occurring carbon molecule, C-60 to C-90, from large natural-occurring fullerene resources.

The technology to extract C-60 from natural fullerene deposits is ground-breaking and a first in this industry. Voyageur will be the first company to be able to mass produce C-60 at a low cost, allowing for multiple drug products to be developed, states Brent Willis, CEO of Voyageur Pharmaceuticals.

The barriers for C-60 based drugs has now been broken, which opens up the industry to develop new effective drugs and health care products on an economic scale, continues Brent Willis.

The API, C-60, is a natural, highly effective super antioxidant, like more common antioxidants (Vitamin C, Vitamin A and Selenium). It scavenges toxic free radicals but it stands out as a notable anti-aging innovation because it selectively scavenges the reactive oxygen species that do the most damage to humans as opposed to just working by osmosis like a normal antioxidant. The anti-aging properties are exciting, as studies in animals have shown the potential to significantly extend life span and to slow the aging process.

Voyageur has begun work on its first C-60 product, C-60X, an immune system booster, natural health product, for daily consumption. Voyageur is creating a C-60 R&D Therapeutics division that will be focused on developing natural health products and drugs. For early cash flow, Voyageur will utilize our Calgary-based manufacturing partners for natural health product sales.

Highlights of C-60 Medical Applications

"Thedifficulty inprocessingof fullerenes has presented a major problem in the search for medicinal applications. This is the breakthrough thatour partner hasrecentlyovercome. The patent-pending technology that can recover economic & high volumes of C-60 from natural fullerene mineral ores is a game changer. This opens the door for Voyageur to become the only company to have the capability to develop and mass produce C-60 based drugs and natural health products at a low cost & high volume, says Brent Willis.

Voyageur plans to develop low cost C-60 radiographic contrast drugs, which encapsulate iodine, gadolinium, and other potential molecules. By utilizing C-60, we may be able to enhance the performance and create the safest radiographic contrast media in the marketplace. Studies have shown that MRI C-60 gadolinium contrast media has a gain of a 500-fold sensitivity on intravital MR Contrast Agents.

Essentially, a carbon-60 molecule is comprised of 60 carbon atoms which are arranged in a unique shape that can be thought of as a 'carbon cage' (like a soccer ball). This sphere makes it possible to be a carrier of other molecules creating a protective shield, allowing C-60 to be an excellent drug delivery vehicle in radiology and healthcare.

This drug delivery system is quite unique to the pharmaceutical industry and our company is proud to begin the innovative steps to develop unique new delivery systems, states Brent Willis.

It has long been known that effective delivery systems are of paramount importance in promoting drug efficacy. This is not only a major milestone for our Company, but potentially a major breakthrough for the entire healthcare industry, continues Willis.The significance of the technological breakthrough, to extract natural fullerene from rock, may well pave the way for a low-cost evolution in the carbon-based health care market. Voyageur is the first company to begin to break down the barrier to market. The C-60 therapeutics division will enhance our Companys ability to become more competitive in the radiographic contrast market and become a leader in the C-60 drug & natural health sector. Fullerene is a gateway for Voyageur to become a leader in a new and exciting carbon medicine field. We will continue to build our From The Earth To The Bottle strategy, to become a fully-integrated competitive force in the API mineral based pharmaceutical industry.

The signed LOI for supply exclusivity will allow Voyageur to produce low cost & high-volume natural carbon-60 API for the pharmaceutical industry. This would allow Voyageur to be fully integrated in the C-60 market and become the only low-cost producer of fullerene based health care products. Voyageur is adding C-60 to its portfolio of active pharmaceutical ingredients (API) minerals for use in the radiographic contrast media markets. There are multiple applications for Fullerene based nano medicines in the healthcare industry, which Voyageur will further research and develop.

Due to confidentiality and pending patents, Voyageur cannot disclose at this time, the identity of the Counterparty.

About Voyageur

Voyageur Pharmaceuticals Ltd. is Canadian public company listed on the TSX Venture Exchange under the trading symbol VM. Voyageur is focused on the development of barite, iodine, and fullerene Active Pharmaceutical Ingredient (API) minerals. The near-term focus is developing barium, iodine radio-contrast products and fullerene-based pharmaceutical products.

Voyageurs goal is to initially generate the positive cash flow from operations using third party GMP pharmaceutical manufacturers. Ultimately, Voyageur has plans to build all the required infrastructure to become 100% self-sufficient with all manufacturing.

Voyageur owns a 100% interest in three barium sulfate (barite) projects including two properties suitable in grade for the industrial barite marketplace, including interests in a high-grade iodine, lithium & bromine brine project located in Utah, USA.

Voyageur is moving forward with its business plan of becoming the only fully integrated company in the radio-contrast medical field, by controlling all primary input costs under the motto of:

"From the Earth to the Bottle"

For Further Media Information or to set up an interview, please contact:

Reader Advisory

Neither the TSXV nor its Regulation Services Provider (as that term is defined in the policies of the TSXV) accepts responsibility for the adequacy or accuracy of this news release.

Cautionary Note Regarding Forward-Looking Statements

This news release contains certain statements or disclosures relating to the Company that are based on the expectations of its management as well as assumptions made by and information currently available to the Company which may constitute forward-looking statements or information ("forward-looking statements") under applicable securities laws. All such statements and disclosures, other than those of historical fact, which address activities, events, outcomes, results, or developments that the Companyanticipates may or will occur in the future (in whole or in part) should be considered forward-looking statement and undue reliance should not be placed on any such statements. In some cases, forward-looking statements can be identified by the use of the words "will", "intends", believes, expects, forecasts, "anticipates", "plans" and similar expressions.

In particular, but without limiting the foregoing, this news release contains forward-looking statements pertaining to the following, the certainty of the disclosed LOI being made into a formal binding agreement; the ability of Voyageur to integrate fullerene into marketable pharmaceutical and healthcare markets; the feasibility and expectation of the Company to bring into production those mining assets it has an interest in; the experience of management and directors of Voyageur and its pharmaceutical manufacturingpartners to execute on its business plan and that of its joint venture company; the economics and risks associated with its business plan; future operations and strategies for development, sales and distribution of mineral and pharmaceutical product;; the Companys ability to successfully penetrate either domestic or foreign pharmaceutical markets; the amount, quality and cost of supply of active pharmaceutical ingredients for potential pharmaceutical products; the ability for Voyageur to meet its joint venture obligations; anticipated registrations with Health Canada or similar foreign bodies for various pharmaceutical products the Company plans to develop, produce and sell; and the ability of the Company to attract investment capital to fund operations and capital expenditures.

The forward-looking statements contained in this news release are made as of the date hereof and the Company undertakes no obligations to update publicly or revise any forward-looking statements, whether as a result of new information, future events or otherwise, unless so required by applicable securities laws.

Source Information:

https://www.ncbi.nlm.nih.gov/pubmed/23785493/ https://phys.org/news/2019-09-fullerene-compounds-virus-infections-hiv.html, https://c60-france.com/media_upload/C60-Fullerene-nano-particles-Inhibit-HIV-Replication.pdf https://www.sesres.com/carbon-60-c60-powder/#buy_c60 https://www.sciencedirect.com/science/article/pii/S0142961212003237https://www.hindawi.com/journals/jnm/2015/565638/https://en.wikipedia.org/wiki/Fullerene https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880842/ https://www.sciencedirect.com/science/article/pii/S0142961212003237 Mitsubishi https://www.azonano.com/article.aspx?ArticleID=47 https://pubs.acs.org/doi/full/10.1021/es801869m https://phys.org/news/2020-03-scientists-water-soluble-fullerene-compounds-medicine.html https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676811/https://pubs.acs.org/doi/10.1021/acsanm.9b01698

Chasing The Elusive Dream Of A COVID Cure – Kaiser Health News

Posted on May 15, 2020 by Danzig

Although scientists and stock markets have celebrated the approval for emergency use of remdesivir to treat COVID-19, a cure for the disease that has killed nearly 260,000 people remains a long way off and might never arrive.

Hundreds of drugs are being studied around the world, but I dont see a lot of home runs right now, said Dr. Carlos del Rio, a professor of infectious diseases at the Emory University Rollins School of Public Health. I see a lot of strikeouts.

Researchers have launched more than 1,250 studies of COVID-19. Pharmaceutical companies are investing billions to develop effective drugs and vaccines to help end the pandemic.

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, was cautious when announcing the results of a clinical trial of remdesivir last week, noting it isnt a knockout. Although remdesivir helped hospitalized COVID-19 patients recover more quickly, it hasnt been proved to save lives.

This [drug] is opening the door, Fauci said. As more companies and investors get involved, its going to get better and better.

Researchers have already announced that they will combine remdesivir with an anti-inflammatory drug, baricitinib now used to treat rheumatoid arthritis in the hope of improving results.

But COVID-19 is an elusive enemy.

Doctors treating COVID patients say theyre fighting a war on multiple fronts, battling a virus that batters organs throughout the body, causes killer blood clots and prompts an immune system overreaction called a cytokine storm.

With so many parts of the body under siege at once, scientists say, improving survival rates will require multiple routes of attack and more than one drug. While some of the experimental medications target the virus, others aim to prevent the immune system from inflicting collateral damage.

There are so many pieces of this, and they will all require different therapies, said Dr. Lewis Kaplan, president of the Society of Critical Care Medicine, whose doctors provide intensive care.

High-tech approaches include using stem cells, virus-specific T cells and synthetic antibodies to neutralize the coronavirus.

Scientists are also taking a fresh look at existing medications that might be repurposed to fight COVID-19. These include antivirals for influenza, arthritis drugs, estrogen patches and even antacids. If repurposed drugs are successful, they could reach patients relatively quickly, because doctors are already familiar with their side effects and safety concerns.

Some doctors are skeptical that drugs for heartburn or hot flashes have any chance of treating a killer like COVID-19.

Dr. Steven Nissen, chair of cardiovascular medicine at the Cleveland Clinic, said he fears that hype over unproven products will harm patients, even if it temporarily boosts company stock prices. Patients who demand antacids or antimalarial drugs being studied in COVID-19 could be harmed by side effects, for example. Those who hoard drugs on the hope of protecting themselves from COVID-19 could deprive other patients of medications they need to stay healthy. Some people may refuse to participate in clinical trials because they fear being given a placebo.

This rush to get every imaginable treatment into a study, its not prudent, Nissen said. Its not good medicine. Its an act of desperation.

Other experts say scientists should cast a wide net.

I dont think we want to rule anything out because it sounds out of the ordinary, said Dr. Walid Gellad, director of the Center for Pharmaceutical Policy and Prescribing at the University of Pittsburgh.

Antivirals In The Spotlight

Antivirals such as remdesivir aim to prevent viruses from replicating, said Dr. Peter Hotez, a professor at Baylor College of Medicine in Houston.

That doesnt always work. A small Chinese study of remdesivir, published last month in The Lancet, found no benefit to severely ill COVID-19 patients. Remdesivir had previously failed when tested against Ebola.

Antivirals tend to be most helpful in the early stages of infection, when most of the harm to the patient is caused by the virus itself, rather than the immune system, Hotez said.

Remdesivir is just one of many antivirals being tested against COVID-19.

International researchers are studying the antiviral favipiravir, developed to fight the flu.

The antimalarial drugs chloroquine and hydroxychloroquine which have been heavily touted by President Donald Trump also have antiviral effects. Although the Food and Drug Administration approved forms of those drugs for emergency use against COVID-19, the agency later warned that they could cause dangerous heart rhythm problems.

A study in the New England Journal of Medicine likewise found no benefit in giving two antivirals used to treat HIV a combination of lopinavir and ritonavir, sold as Kaletra in adults hospitalized with severe COVID-19.

Harnessing The Immune System

One of the therapies generating excitement is also one of the oldest: antibody-rich blood from COVID survivors.

The immune system produces antibodies in response to invaders such as viruses and bacteria, allowing the body to recognize and neutralize them. Antibodies also recognize and neutralize the virus the next time that person is exposed.

Doctors hope that patients who develop antibodies against the novel coronavirus will become immune, at least for a few years, although this hasnt been proved.

Scientists developing this convalescent plasma are studying whether COVID-19 survivors can share this immunity with others by donating their plasma, the liquid part of blood that contains antibodies, said Dr. Shmuel Shoham, an associate professor of medicine at the Johns Hopkins University School of Medicine.

In addition to treating people who are already sick, donated plasma could potentially prevent people exposed to the virus such as health care workers from developing symptoms.

Donated antibodies and any immunity they might provide dont last forever, said Dr. William Schaffner, a professor at the Vanderbilt University Medical Center. The body destroys aging antibodies as part of its routine maintenance, he said. In general, half of donated antibodies are eliminated in about three weeks.

The use of convalescent plasma goes back more than a century. It was used during the 1918 flu pandemic and was shown to improve survival during the 2009-10 H1N1 pandemic.

Doctors dont know yet whether convalescent plasma will benefit people with COVID-19.

In general, convalescent plasma is expected to be more effective in preventing illness than in treating it. It may be less likely to help someone in intensive care, Shoham said.

Researchers are also studying the use of prepackaged plasma, called intravenous immunoglobulin, in COVID patients. This product, known as IVIG, is taken from healthy donors in the general population and has long been used to help patients with weakened immune systems fight off infections. Hospitals keep it in stock and some are already using it to treat COVID patients.

Although the antibodies in prepackaged IVIG dont specifically target the coronavirus, researchers hope they will tamp down the immune response.

In a third form of immune therapy, researchers are trying to identify the specific antibodies that are most important for neutralizing the coronavirus, then reproduce them as drugs called monoclonal antibodies. Monoclonal antibodies are already used to treat a variety of conditions, from cancer to rheumatoid arthritis and migraines.

When we give people an antibody, they are immediately at least partially immune to that specific virus, said Dr. James Crowe, director of the Vanderbilt Vaccine Center, who hopes to have antibodies ready for a clinical trial in a few months. Were moving the immune system from one person to another.

Ideally, doctors would develop a very potent monoclonal antibody or a cocktail of antibodies for COVID-19 patients, to ensure the best chance of success, Crowe said. But manufacturing these drugs can be complicated, expensive and time-consuming.

Making two antibodies would be at least twice as complicated as making one, Crowe said. A cocktail might be preferred, but cocktails are harder to move quickly.

Calming The Immune System

In most cases of COVID-19, the immune system neutralizes the coronavirus and patients recover without going to the hospital.

For reasons that doctors dont totally understand, the immune system of some COVID-19 patients becomes hyperactive, attacking not just the virus but the patients own cells. A cytokine storm, in which the immune system floods the body with inflammatory chemicals, can do more damage than the virus itself.

In an effort to calm the immune system, researchers are testing immune-suppressing drugs, including monoclonal antibodies already used to treat autoimmune diseases such as rheumatoid arthritis, said Dr. Amesh Adalja, a senior scholar at the Johns Hopkins Center for Health Security.

Health care giant Roche is conducting large clinical trials of its drug, Actemra, in the hope of preventing cytokine storms, which can cause organ failure and a life-threatening condition called sepsis. Actemra is designed to lower levels of an inflammatory chemical, interleukin-6, which has been found to be elevated in some COVID-19 patients.

Scientists are also studying similar drugs, anakinra and siltuximab.

Another immune suppressant from Regeneron and Sanofi, called Kevzara, has had disappointing results in clinical trials. The manufacturers plan to continue studying the drug to see if it can help certain types of patients.

Dr. Anar Yukhayev, a New York OB-GYN who was hospitalized with COVID-19 on March 16, agreed to join a clinical trial of Kevzara.

I was having so much trouble breathing that I was desperate for anything to help, said Yukhayev, 31, who was treated at Long Island Jewish Medical Center.

About 36 hours after receiving an infusion, as Yukhayev was being treated in intensive care, his symptoms began to improve. He was able to avoid being put on a ventilator. Doctors didnt tell him if he received Kevzara or a placebo, but his liver enzymes also began to rise, suggesting the organ was under stress. Elevated liver enzymes are a known side effect of Kevzara.

Yukhayev made a full recovery and went back to work full time April 13. He donated his plasma to researchers.

Until vaccines and other preventive medicines are developed, the best way to prevent coronavirus infections is to maintain social distancing, Adalja said.

Social distancing is a blunt tool, he said, but its all that we have.

Read the original here:
Chasing The Elusive Dream Of A COVID Cure - Kaiser Health News

Dr. Wellness The Manila Times – The Manila Times

Posted on April 25, 2020 by Danzig

DR. JOEL LOPEZMedical Director, J.Lopez, M.D. Medical Group

Treating the root of the illness, and not the symptoms, is key to enduring healthcare that is his prescriptionA strong and healthy immune system is definitely our bodys first line of defense [against] Covid-19 (coronavirus disease 2019) and other illnesses, declares Dr. Joel Lopez, medical director of the J. Lopez, M.D. Medical Group.

Dr. Lopez was about to start a two-hour webinar (online seminar) for medical professionals and laymen on How to Fortify your Immune System and Vitamin C when Boardroom Watch reached him on April 6.

Holistic treatmentsPending the availability of a safe and effective vaccine for Covid-19, Dr. Lopez recommends nutritional supplements to boost ones immune system. Vitamin C should be given to high-risk individuals, such as frontliners, the elderly and the frail, to help boost [their] innate natural immunity, he says.

American chemist, biochemist and chemical engineer Linus Carl Pauling, a double Nobel laureate for his extensive studies on the benefits of Vitamin C, is Dr. Lopez role model.

There are numerous studies showing that vitamins A, C, D3 and E, as well as minerals such as magnesium, selenium and zinc, can be effective prophylaxis against any type of infection, Dr. Lopez says, adding some wry advice: To cope with stress during the Covid-19 [pandemic], lessen the time watching or listening to news you find upsetting.

Dr. Lopez, who has set up clinics in Alabama, Florida, Indiana, Illinois and California, is now based in the Philippines, caring for his aged mother and giving back to his countrymen. He still maintains his San Francisco office, though. My mom (Dr. Adelina San Juan-Lopez) is a dentist, but most of her siblings are doctors, while several cousins on both sides of the family are medical doctors who practice locally and in the US. Im the only specializing in integrative, biological and regenerative medicine, he says.

Hi dad Tomas, an accountant who sold medical supplies and equipment, passed away two years ago.

NATURES WAY Dr. Lopez (back row, far left) with colleagues during his residency at Mercy Hospital & Medical Center. Below is him sweating it out at the gym. CONTRIBUTED PHOTOS

Back on home ground in 2013, Dr. Lopez opened a clinic at The Medical City on Ortigas Avenue, Pasig City, followed last year by a 28-story outpatient facility in Poblacion, Makati City that deals with integrative, holistic, functional, biological and orthomolecular (right molecules in the right amounts) medicine. His mission statement is to transform, boost, and maintain patients overall wellness.

Filipinos are very receptive to this type of medicine, Dr. Lopez says. Growth can be achieved by educating the public about the basics of nutrition/prevention. He has been practicing holistic medicine for 16 years. To be able to train more medical professionals in this field is his long-term goal.

I prefer that they shadow me while Im seeing clients, Dr. Lopez says. For more theoretical training, I share my textbooks and recommend conferences that I [attended], such as the American Academy of Anti-Aging Medicine, the Institute of Functional Medicine and the Orthomolecular (right molecule) Medicine Group.

Dr. Lopez, who is 54, emphasizes that his biological age is younger, and more important

For optional results, he partners with the client to heal the body, mind, spirit and emotions. He addresses premature aging factors, such as nutritional deficiencies, chronic inflammation, hormonal imbalance, oxidative stress (fatigue, cramps, pain) and poor detoxification mechanisms.

We treat the underlying causes of illness, rather than just treating symptoms. My practice is based on the 7Ps: Personalized, Predictive, Precise, Preventive, Proactive, Partnership and Pharmaceutical grade supplements, he says.

He uses natural remedies (macro and micronutrients, herbals), along with bioidentical (man-made) hormones, peptides, (short strings of amino acids), cell extracts and homeopathy (treatment using natural substances). He applies medication only in an emergency.

Leave it to natureDr. Lopez says integrative medicine allows him to harvest the wisdom of traditional practices and fused with the continued growth of modern science. He also uses a four-step series, called Methodical Dynamics, to furnish a systematic approach to treatments.

Health should be approached holistically since the body and mind are connected, says Dr. Gracielle Consing, The Medical Groups operations manager.

Dr. Daniel J. Dunphy, The Medical Groups visiting practitioner, adds: The good physician cures illness, while the excellent physician prevents it. Harvie Baron, the Medical Groups nutrition coach and food educator, lives by this principle: Transform your health through the healing power of food.

As vice president and founding member of the Preventive Regenerative, Integrative Medical Association since 2014, Dr. Lopez aims to bring optimizing health for a youthful life practice into the mainstream and set up practice standards.

The aging process starts at 30 when our body doesnt produce enough hydrochloric acid to digest food protein, resulting in less less amino acid supplying the brain, he says. One or two teaspoons of apple cider before meals can help the body digest food better. It mimics the effect of hydrochloric acid in the body and is a treatment for indigestion.

Sometimes, you just have to go back to nature to solve nagging health problems and live longer, says Dr. Lopez. Walnuts prevent memory from declining. Fish, especially the small ones like the humble dilis (anchovies), have fatty acids that prevent inflammation. Clean water, air, sleep, exercise, stress reduction, detoxification and nutritional supplements are daily prevention practices.

Because diet influences aging, Dr. Lopez says he eats organic, in-season produce. These contain no hormones that destroy cells. When I wake up in the morning, that means Im still around for a purpose: To glorify Him in all things I do, in my professional and personal life. I read the Bible. He drinks a healthy milkshake for breakfast, as well as nutritional supplements. He exercises at the gym in the late afternoon or early evening. Exercise is one of the best anti-aging tools. It improves the muscle mass and lessens body fat, he says.

Dr. Lopez graduated with a bachelor of science in medical technology in 1986, followed by a doctor of medicine degree in 1990 from Far Eastern University. As a volunteer physician in 1992, he taught holistic healthcare in isolated rural areas in Palawan province, as well as on medical missions in Thailand. He later completed his degree in internal medicine at the University of Illinois at Chicago and his residency at the Mercy Hospital & Medical Center in Chicago.

In 1996, he trained with one of Americas well-known pioneers in alternative medicine, Dr. Gus Prosch. He also taught yoga and chi gong (exercises for cultivating healing energy) on the side.

Dr. Lopez is a very good, compassionate and innovative physician. He is a very dedicated and tireless medical researcher who is always looking for new ways to holistically heal his patients, says Dr. Chiedu J. Nchekwube of Merrillville, Indiana, under whom Dr. Lopez worked directly in 2010.

But perhaps, the best testimonies come from those whom Dr. Lopez has treated. These are recorded on The Medical Groups website.

Joel is not going to throw a bunch of pharmaceuticals at you. He will get to the root cause of why your body is not in balance, and work to adjust it naturally, as much as possible, says Jaye Wittaker, a US-based patient.

Avegay L. from Fremont, California, adds: Dr. Lopez will not just treat the symptom of the disease, but will also treat the root and cause of the problem. I want to age gracefully and to look and feel healthy. Even my boyfriend is now being treated by Dr. Lopez.

He explains all tests so we can understand everything. He takes the time to answer our emails and phone calls when we need advice or help, say Sandi and Fred Herrera, a Filipino couple living in Manila.

Through diagnosis, detoxification, healing and rejuvenation, Dr. Lopez regularly reaches his ultimate goal. And that is to have patients take active control of their health and wellness.

* * *

WHOS AFRAID OF AGING?

Dr. Joel Lopezs individual approach in managing clients nutritional concerns is reflected through four Methodical Dynamics pillars. Your body is a home that you will live in forever, he says. Embrace, love and take care of it. Its the best thing you can ever do for yourself.

Step 1: Early Detection allows us to see what the body needs and how it can be better aided. This describes a 360 degree-approach to your consultation. Strategically designed questions are combined with the test results from the Medical Groups Integrative Innovations. This process allows the physician to find the best approach to the clients current concerns or preventive treatment.

Step 2: System Destress tackles the symptoms and possible causes that prevent the individual from reaching optimal health. It aids in body detoxification to allow the body to best receive the recommended treatments. Our bodies go through so much because of the environment and diets alone. This step in the Methodical Dynamics series helps the body to purify itself for better absorption of nutrients.

Step 3: Restore brings the body into a state of health that allows its very self to maximize its very potentials. Restore allows the body to regain its optimal state. Innovations in the practice of Integrative Medicine are used to allow the body to heal itself naturally.

Step 4: Regenerate stabilizes the foundations of the body with the support needed for the patients goals. Regenerate helps rebuild healthy cells as the person ages. With J. Lopez, M.D. Medical Group, Inc., regeneration supports these building blocks using the recommended nutrients and minerals each individual needs. This approach supports clients ageing process for the long term.

Addressing the potential impact of coronavirus disease (COVID-19) on Double Aspheric Lens Market Dynamics, Segments and Supply Demand 2019-2061 -…

Posted on May 4, 2020 by Danzig

A recent market study on the global Double Aspheric Lens market reveals that the global Double Aspheric Lens market is expected to reach a value of ~US$ XX by the end of 2029 growing at a CAGR of ~XX% during the forecast period (2019-2029).

The Double Aspheric Lens market study includes a thorough analysis of the overall competitive landscape and the company profiles of leading market players involved in the global Double Aspheric Lens market. Further, the presented study offers accurate insights pertaining to the different segments of the global Double Aspheric Lens market such as the market share, value, revenue, and how each segment is expected to fair post the COVID-19 pandemic.

Get Free Sample PDF (including COVID19 Impact Analysis, full TOC, Tables and Figures) of Market Report @ https://www.marketresearchhub.com/enquiry.php?type=S&repid=2576675&source=atm

The following doubts are addressed in the market report:

Key Highlights of the Double Aspheric Lens Market Report

The presented report segregates the Double Aspheric Lens market into different segments to ensure the readers gain a complete understanding of the different aspects of the Double Aspheric Lens market.

Do You Have Any Query Or Specific Requirement? Ask to Our Industry [emailprotected] https://www.marketresearchhub.com/enquiry.php?type=E&repid=2576675&source=atm

Segmentation of the Double Aspheric Lens market

Competitive Outlook

This section of the report throws light on the recent mergers, collaborations, partnerships, and research and development activities within the Double Aspheric Lens market on a global scale. Further, a detailed assessment of the pricing, marketing, and product development strategies adopted by leading market players is included in the Double Aspheric Lens market report.

The following manufacturers are covered:NikonCanonPanasonicHOYAAsahi Glass (AGC)SchottZEISSTokai OpticalSEIKOCalin TechnologyKinko OpticalLARGAN PrecisionGeniuS Electronic Optical (GSEO)Asia opticalSunny Optical TechnologyMingyueLante

Segment by RegionsNorth AmericaEuropeChinaJapanSoutheast AsiaIndia

Segment by TypeCamerasOptical InstrumentsOphthalmicMobile phoneOther

Segment by ApplicationGlassPlasticOther

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Addressing the potential impact of coronavirus disease (COVID-19) on Double Aspheric Lens Market Dynamics, Segments and Supply Demand 2019-2061 -...

New Study Suggests the Consequences of Oxidative Stress on Telomeres – Truth In Aging

Posted on May 12, 2020 by Danzig

A decade ago, scientists won the nobel prize for connecting the dots between telomeres and aging. Telomeres are the protective caps on the ends of the strands of DNA called chromosomes. Telomeres shorten every time a cell divides. When they become very short, they trigger cell crisis and cell death.

Since this discovery was made, researchers have found new insights into telomeres and their connection to wrinkled skin, as well as how their length might be extended.

Scientists have uncovered new information on telomeres that could help combat the effects of inflammation and aging. Researchers from the University of Pittsburg recently discovered how oxidative stress plays a critical in the link between telomeres and cancer. I dont want to blind you with science (telomeres are a complex area), but every breakthrough into telomeres will ultimately equal a breakthrough in understanding how we age and how we can keep cells including our skin cells healthy.

Telomeres are composed of repeated sequences of DNA. The results from this study suggest that the mechanism by which oxidative stress accelerates telomere shortening is by damaging the DNA precursor molecules, not the telomere itself. This will have a big impact on appreciating how to manage oxidative stress to prevent aging and diseases such as cancer.

At Stanford University School of Medicine, scientists claim they can now lengthen teleomeres. Skin cells with telomeres lengthened by the procedure were able to divide up to 40 more times than untreated cells (source).

However, longer teleomeres is not necessarily associated with a longer life (source). Indeed, those naysayers say that good diet and an exercise regimen will do that. Yet, it does seem that preventing further shortening of the telomeres could be beneficial, especially for aging skin. Telomeres are likened to the tips of shoelaces that stop them unraveling and so you really want to be thinking about how to stabilize your telomeres. Happily, advances in skin care can help you out. There are three approaches to consider: special ingredients that target telomeres, ingredients that prevent oxidative damage (known, of course, as antioxidants) and stem cells.

Target your telomeres

One very interesting ingredient is called astragalus, and although it is rare, we do have a couple of Truth In Aging finds with it. But first, what is it and how does it work? In 2008, a UCLA AIDS Institute study found that a chemical they called TAT2 from the astragalus root, which is frequently used in Chinese herbal therapy, can prevent or slow the progressive shortening of telomeres. It can be found in Prana Reishi Mushroom Shield ($42 in the shop) and ExPrtise Effective Anti-Aging Face Serum ($120 in the shop).

Another ingredient to look for is treprenone, also marketed under the name of Renovage. Its promise is to stabilize telomeres, so at the very least they won't shorten. Maintaining telomere length extends the Hayflick Limit (the rate at which cells turn over before conking out completely) by one third. Youll find treprenone (Renovage) in Your Best Face Correct ($150 in the shop) Your Best Face Boost ($65 in the shop.

Amp up with antioxidants

The research is clear: Preventing oxidative damage is the job of an antioxidant. Free radicals are charged chemical particles of oxygen that enter into destructive chemical bonds with organic substances such as proteins, as explained by Gerald Imber, MD. Antioxidants limit the production of free radicals and therefore help prevent oxidative stress. There are many sources in plants, and vitamins are also antioxidants.

There are 33 antioxidants in Skin 2 Skin Aging Intervention Cream ($73 in the shop), including the universal antioxidant alpha lipoic acid. The powerful antioxidants in Your Best Face Rescue ($145 in the shop) include spin trap, an advanced form of vitamin C and EGCG. Bee venom has some 18 active compounds include antioxidants, peptides with powerful anti-inflammatory actions, and enzymes. It is the key ingredient in LaCrme Beaut Luxurious Bee Venom Rich Face Treatment Cream ($202 in the shop).

Look for plant stem cells

Plant stem cells never age. British scientists found that plant stem cells were much more sensitive to DNA damage than other cells. Once they sense damage, they trigger death of these cells before it spreads and causes more. In addition, they have the ability to stimulate cell renewal and replace specific cells in need of repair.

Ao Skincare Raw Nourish AM Treatment ($65 in the shop) has the powerful antioxidant astaxanthin and plant stem cells.

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New Study Suggests the Consequences of Oxidative Stress on Telomeres - Truth In Aging

Discovery links glucose metabolism abnormalities to Alzheimer’s disease – New Atlas

Posted on April 18, 2020 by Danzig

A new study, funded by the National Institutes of Healths National Institute on Aging, is offering novel insights into how protein expressions can be altered during the course of Alzheimers disease. The research suggests proteins regulating glucose metabolism and the anti-inflammatory activity of brain immune cells are linked with Alzheimers pathology, and could point researchers toward new treatment and diagnostics.

The study, published in the journal Nature Medicine, comes out of a larger project called the Accelerating Medicines Partnership for Alzheimers Disease (AMP-AD). This NIH-led venture is designed to advance novel diagnostic and treatment targets while bringing together government, industry, and nonprofit organizations.

This new paper describes the results of the largest Alzheimers-related protein study conducted to date, gathering over 2000 brain tissue samples and around 400 cerebrospinal fluid samples from research centers across the United States. Expression patterns of more than 3000 proteins were measured, looking at differences between healthy subjects and Alzheimers patients at different stages of the disease.

This large, comparative proteomic study points to massive changes across many biological processes in Alzheimers and offers new insights into the role of brain energy metabolism and neuroinflammation in the disease process, explains Suzana Petanceska, the NIA director managing the AMP-AD Target Discovery Program.

In both cerebrospinal fluid and brain tissue samples the research revealed higher expressions in Alzheimers patients of proteins involved in glucose metabolism and anti-inflammatory processes. Importantly, these elevated protein levels were also detected in subjects with preclinical Alzheimers, suggesting as well as a potential new treatment target, the protein abnormalities could serve as an effective early-stage biomarker of the disease.

Weve been studying the possible links between abnormalities in the way the brain metabolizes glucose and Alzheimers-related changes for a while now, say Madhav Thambisetty, one of the authors on the new study. The latest analysis suggests that these proteins may also have potential as fluid biomarkers to detect the presence of early disease.

The researchers note this study describes what is known as a fundamental research finding. This essentially means the study is outlining a foundational discovery, from which future research will hopefully be able to build new treatments or diagnostics. Suzana Petanceska notes this work has already been spread around the Alzheimers research community with the goal of inspiring new treatment targets.

The data and analyses from this study has already been made available to the research community and can be used as a rich source of new targets for the treatment and prevention of Alzheimers or serve as the foundation for developing fluid biomarkers, she concludes.

The study was published in the journal Nature Medicine.

Source: NIH

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Discovery links glucose metabolism abnormalities to Alzheimer's disease - New Atlas

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