reGeneRations 2013 – Biosciences

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reGeneRations 2013 - Biosciences Bioengineering, IIT Bombay Welcomes You!
The Department of Biosciences and Bioengineering (BSBE) is a nodal center for applying science and engineering principles to further fundamental knowledge and applications in biology and biomedical engineering. The BSBE department aims to create an ambience for the smooth pursuit of scholarly activities in research and education, to make an international impact, and to produce future leaders in the field of Biosciences and Bioengineering.

By: Sandeep Kumar Khichar

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reGeneRations 2013 - Biosciences

Bioengineering Overview Sloan Career Center

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Biomedical engineers develop devices and procedures that solve medical and health-related problems by combining their knowledge of biology and medicine with engineering principles and practices. Many do research, along with medical scientists, to develop and evaluate systems and products such as artificial organs, prostheses (artificial devices that replace missing body parts), instrumentation, medical information systems, and health management and care delivery systems. Biomedical engineers also may design devices used in various medical procedures, imaging systems such as magnetic resonance imaging (MRI), and devices for automating insulin injections or controlling body functions. Most engineers in this specialty need a sound background in another engineering specialty, such as mechanical or electronics engineering, in addition to specialized biomedical training. Some specialties within biomedical engineering are biomaterials, biomechanics, medical imaging, rehabilitation engineering, and orthopedic engineering.

Major advances in Bioengineering include the development of artificial joints, magnetic resonance imaging (MRI), the heart pacemaker, arthroscopy, angioplasty, bioengineered skin, kidney dialysis, and the heart-lung machine.

Bioengineering Resources

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Note: Some resources in this section are provided by the US Department of Labor, Bureau of Labor Statistics and the Whitaker Foundation.

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Bioengineering Overview Sloan Career Center

‘Soft’ side of bioengineering poised to make big impacts – Arizona State University

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Arizona researchers, educators, students and representatives of industry, government agencies and health care institutions gathered at the annual ASU Molecular, Cellular and Tissue Bioengineering Symposium in 2016 and 2017 to discuss the potential these fields hold for sparking medical advances. Photo by: Marco-Alexia Chaira/ASU Download Full Image

The main thrust of biomedical engineering has long involved the hardware that the field produces devices, tools, machines, electronics and prosthetic apparatuses.

Now the spotlight is rapidly being shared by engineers and scientists who are seeking to solve medical challenges through their increasing ability to manipulate cells, molecules, genes, proteins and neural systems those so-called soft, pliant and sometimes living biomaterials.

So, about four years ago, it really started to make sense to form a group to strategize about how we could grow this area at ASU, both in the labs and the classrooms, said Haynes, a synthetic biologist and assistant professor of biomedical engineering in ASUs Ira A. Fulton Schools of Engineering.

We needed to start connecting with each other, to share knowledge and to collaborate to bring these new things happening in the biomedical field to the forefront here, said Rege, a professor of chemical engineering in the Fulton Schools.

The Molecular, Cellular and Tissue Bioengineering Group made its public debut of sorts with the inaugural Molecular, Cellular and Tissue Bioengineering Symposium at ASU in 2016, followed by a second symposium last spring that drew almost 150 participants, nearly doubling attendance at the first event.

The gatherings included not only university faculty and graduate students from across Arizona but also representatives from industry and state health agencies.

Audiences saw presentations and heard talks about an expanding array of biomedical techniques being developed that hold promise for treating diseases, healing damaged organs and alleviating various disorders.

There are therapeutic gene editing and DNA sequencing techniques being developed with the aim of curing disease.

Researchers are exploring the use of certain proteins produced by our bodies to treat diseases proteins that could potentially be more effective than the chemical compounds in the drugs that are now widely used.

With our ability to figure out how DNA is expressed and translated into a protein, we now have a much clearer picture of all the different types of coding sequences in DNA and the proteins that are produced by the body, Haynes explained.

Assistant Professor Karmella Haynes (right) says a stronger emphasis on educating students about the biological side of biomedical engineering can broaden their skills and boost their career prospects. Photo by: Jessica Hochreiter/ASU

That capability, she said, enables us to take a healthy cell and compare it to a diseased cell, and then say This is what is right in the healthy cell and these are the things that are wrong in the unhealthy cell. Then we could introduce the right things into the diseased area to try to fix it.

Reges research team is investigating other aspects of such regenerative medicine.

One project involves experimentation with efficiently delivering therapeutic molecules into cells that could target areas of disease.

Techniques like that could also be part of new processes to perform body tissue repair, helping to seal internal organs after surgical incisions in conjunction with the use of laser light to activate sealing and even healing organ tissues damaged by injury or disease.

Other Fulton Schools faculty members are doing work that demonstrates the myriad possibilities of applying new bioengineering skills to improve human health.

Assistant Professor Jeffrey La Belles team is developing implantable and wearable point-of-care sensing systems for disease diagnosis and management.

The technologies utilize molecular recognition of such things as enzymes, antibodies and DNA for sensing particular molecular targets that provide information about certain health conditions.

By sensing multiple biomarkers, the devices can help medical professionals better determine proper care by more accurately assessing patients conditions, La Belle said. They can be particularly effective in enabling people with diabetes, cardiovascular disease and abdominal organ transplants to monitor their health, and for improving evaluation of the status of trauma patients.

Associate Professor Xiao Wang is involved in the design and construction of gene circuits. That entails deeper understanding of the bodys complex gene-regulation networks and what triggers the cell differentiation process, by which stem cells transform into a range of specialized cells critical to the functioning of essential bodily systems.

The aim is to find ways to more effectively determine cell fate, Wang said. Controlling those transitions would make it possible to produce cells designed to help treat infections and diseases, and repair tissues and organs.

Achieving that could help reduce the need for transplants and improve therapies and treatments for spinal injuries and perhaps even Alzheimers Disease and blindness.

Associate Professor Sarah Stabenfeldt is focusing on new and improved therapeutics and diagnostics for brain injury, employing techniques springing from discoveries in molecular biology, neuroscience and materials science to develop and evaluate those diagnostic and treatment systems.

She is experimenting with the use of engineered nanobodies therapeutic proteins derived from antibodies that contain structural and functional properties of naturally occurring antibodies.

The goal is to develop nanoparticle systems that can be introduced into the bloodstream as targeting probes that locate the molecular and cellular source of brain damage.

Those tiny probes would be able to recognize the complexity and severity of neural injury to the brain at the molecular level, thus providing more relevant information to guide treatment of traumatic brain injury, Stabenfeldt said.

Assistant Professor Rachael Sirianni is employing similar approaches to develop more effective treatments for cancer and other degenerative diseases.

Sirianni is an adjunct biomedical engineering faculty member with the Fulton Schools whose primary appointment is with the Barrow Neurological Institute at St. Josephs Hospital and Medical Center in Phoenix, where she runs an academic research program that includes joint ASU/BNI neuroscience endeavors.

She is exploring the use of biomaterials for targeted drug delivery. tissue engineering and medical imaging. Shes confident that work in in these and related areas will eventually help bring about significant medical advances.

The range of problems we can tackle and the knowledge we can gain through these emerging aspects of bioengineering will eventually lead to better therapeutics and a big overall impact on the future of clinical care, she said.

Professor Kaushal Rege (second from left) says the Molecular, Cellular and Technology Group will work to earn more support for research training programs for graduate and postdoctoral students. Photo by: Nora Skrodenis/ASU

There are obstacles that must be overcome to achieve the scientific and engineering capabilities necessary to fulfill that promise, she added, but she believes collaborations like those being fostered by the Molecular, Cellular and Tissue Bioengineering Group could speed progress.

Along with about a half dozen other Fulton Schools faculty, colleagues in ASUs School of Life Sciences, the School of Molecular Sciences and research specialists with the Biodesign Institute are also engaged in advancing knowledge in molecular, cell and tissue biology.

Much of that work has drawn support from the likes of the National Science Foundation, the National Institutes of Health, the ASU Foundations Women & Philanthropy program, the American Heart Association and the Arizona Biomedical Research Commission, which also provided $20,000 to help fund this years ASU Molecular, Cellular and Tissue Bioengineering Symposium.

The ABRC, a part of the Arizona Department of Health Services, sees significant benefits for the state in helping to create a shared sense of community among engineers, scientists, industries and healthcare institutions interested in making medical advances, said Jennifer Botsford, the commissions program manager.

The faculty group has the potential to create opportunities for cross-fertilization of ideas that push the boundaries of science, said Betsy Cantwell,vice president of research for ASUs Knowledge Enterprise Development office

Their work is not only necessary, but genuinely innovative and inclusive, as demonstrated by their national stature and international connections, Cantwell said.

Such endorsements are motivating the group to put plans into action to more solidly establish its identity and pursue its long-range goals.

Haynes is hoping that by next year the symposium will start to become more of a regional event and draw prominent experts and industry leaders from throughout the Southwest.

She and Rege also hope to encourage more serious discussion with ASU leaders about ideas for a future lab complex or even a building where the universitys biomedical researchers could be headquartered.

To optimize our resources and make full use of our talents, its important to have an environment that allows us to see and talk to each other about our individual work, Rege said. That is how ideas get generated and collaborations happen.

On one front, the groups aspirations are already taking shape.

The Fulton Schools biomedical engineering program is in the process of launching a new curriculum track that will make this soft, squishy side of the field more of an educational focal point at ASU.

This is a huge deal, Haynes said, because we can offer more to students who want a stronger combination of medical education and engineering thats going to open up their career possibilities.

The group seeks to not only attract more funding for faculty research but also for research training programs for graduate students and postdoctoral students.

That would be a significant step toward elevating ASU among medical science and engineering education leaders.

Said Rege: We want this to be a place where people can come to see and learn about and contribute to really big things happening in all these fields. Thats our vision.

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'Soft' side of bioengineering poised to make big impacts - Arizona State University

Innovation Shines at CREATIVATE – Lehigh University News

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So Huffman decided to create a device that can be attached to a car and, at the touch of a button, control the vehicles noise level. As such, his company, Valvetronic Designs, was born: When the car is in loud mode, the valved exhaust system he created is open and the exhaust is able to flow right out of the car. However, in quiet mode, the exhaust is trapped within the device, preventing it from making any loud noises.

As Valvetronic Designs began to grow, Huffman sought the help of his roommate, Scott Gruninger 20.

I just brought this excellent man on because I'm terrible at managing my financials and such, Huffman said. So I need a man to help me with supply chain financials, and he's the guy.

Said Gruninger: Before I worked with Austin I had a 3-D printing business...And then, Austin and I, being roommates, we bounced ideas off of each other and he was like, Why don't you come do this full time with me? And I was like, Yeah!

Huffman is a supply chain management major, and Gruninger studies management consulting.

Were on track to do $30,000 in sales this month...We dont have any overheads because its just us, Huffman said. We outsource our manufacturing, and we build our supplies off site, so it doesn't cost us a bunch to make these systems, and it's just pushing marketing out. Getting my name out there is how we're going to [grow].

Lauren Farrell 13 combined two of her passions to create luxury handbags for sports fans.

At Lehigh, Farrell studied design and entrepreneurship.

I remember that the entrepreneurs had this passion that was totally contagious and I said, I have no idea what I want to do, but I want to be like them.

Farrells inspiration came about when she discovered a lack of fashionable bags on the market that met the strict regulations of sports centers. She decided to create a line of bags that met those restrictions, but still could appeal to the woman who loves fashion.

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Innovation Shines at CREATIVATE - Lehigh University News

The Presto Patch by BeatSync Technologies – Video

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The Presto Patch by BeatSync Technologies
Introducing The Presto Patch by BeatSync Technologies - A Novel Set of Patch Electrodes set to become the standard in modern shock therapy. Designed by a group of 8 Biomedical Engineering students at the Johns Hopkins University, the Presto Patch gives clinicians a better option when it comes to defibrillation and cardioversion. With the help of our sponsor, Dr. Todd Cohen, who has over 30 patents in the field, as well as with the help of the Johns Hopkins Hospital, the Johns Hopkins Center for Bioengineering Innovation and Design together with the support of the top electrophysiologists around the country, the Presto Patch is on its way to saving lives. Patent pending.From:ppod73Views:10 0ratingsTime:02:36More inScience Technology

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The Presto Patch by BeatSync Technologies - Video

Student Bios – Xiao Yun, Class of 2016 – Video

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Student Bios - Xiao Yun, Class of 2016
Student Bios Season 2! Meet Xiao Yun from the Class of 2016! Xiao Yun talks about why she decided to make a switch from Bioengineering to Medicine, how she has benefited from the TeamLEAD curriculum and her advice to prospective students of Duke-NUS.From:InsideDukeNUSViews:0 0ratingsTime:03:01More inEducation

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Student Bios - Xiao Yun, Class of 2016 - Video

From idea to innovation: A conversation… – Manuel Desco – Video

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From idea to innovation: A conversation... - Manuel Desco
From idea to innovation: A conversation about experiences in academia for generating and realizing innovation Moderated by Manuel Desco, Head of Bioengineering Aerospace Engineering Department, Univ. Carlos III. Instituto de investigación Sanitaria Gregorio Marañón, Madrid Many universities have (or are considering) implemented programs intended to promote and provide training in innovation for their students and staff. These programs vary considerably, yet all have enjoyed demonstrable success. The programs implemented or experienced by the speakers in this session represent a diverse cross section of these kinds of programs. This session is referred to as a conversation because it is intended to be interactive. Speakers will each provide very brief remarks, after which an extended conversation with questions from the moderator and the audience. Training the next generation of global medical innovation leaders: An integrated approach Youseph Yazdi, Executive Director, Center for Bioengineering Innovation Design, Johns Hopkins University First hand experiences in medicine, science and technology: An ideal platform for future biomedical leaders (see abstract in bio) Brian Pereira, Chair Advisory Board for MIT-Harvard Biomedical Enterprise Program Getting ideas out of the academy and into practice: A view from within a major research laboratory Yoel Fink, Director Research Laboratory for Electronics, Professor of Materials Science, Department of Materials Science and ...From:MVisionMadridViews:0 0ratingsTime:01:22:52More inScience Technology

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From idea to innovation: A conversation... - Manuel Desco - Video

Leadership panel: How individuals can build and become innovation hubs – Fiona Murray – Video

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Leadership panel: How individuals can build and become innovation hubs - Fiona Murray
Moderated by Fiona Murray, Professor of Management of Technology Faculty Director, Entrepreneurship Center, MIT Sloan School of Management The prospect of building an innovation hub is daunting from virtually any perspective. These examples show ways in which enterprising individuals have, through different approaches, established a vibrant multi-professional network that attracts innovators and promotes translation of ideas to practice. Creating an innovation hub from within: Building a community of innovators within a clinical medical center Julio Mayol, Professor of Surgery at Universidad Complutense de Madrid, Director of the Innovation Unit, Hospital Clínico San Carlos Innovation emerges from adversity: Perspectives as an academic, clinician and CEO (see abstract in bio) Brian Pereira, CEO emeritus, AMAG Pharmaceuticals, CEO emeritus, Tufts New England Health Care Foundation, Adjunct Professor of Medicine, Tufts University School of Medicine Breaking through the professional barriers that separate engineering, medicine and business: Opportunities for a more seamless interface Manuel Desco, Head of Bioengineering Aerospace Engineering Department, Univ. Carlos III. Instituto de investigación Sanitaria Gregorio Marañón, Madrid The economic potential of technology Tim Harper, CEO CientificaFrom:MVisionMadridViews:1 0ratingsTime:01:16:49More inScience Technology

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Leadership panel: How individuals can build and become innovation hubs - Fiona Murray - Video

The Molecules We Eat: Amy Rowat at TEDxUCLA – Video

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The Molecules We Eat: Amy Rowat at TEDxUCLA
Amy Rowat is Assistant Professor at in the UCLA Department of Integrative Biology Physiology, and member of the UCLA Bioengineering Department, Jonsson Comprehensive Cancer Center, Business of Science Center, Broad Stem Cell Research Center, and Center for Biological Physics. Rowat completed her training at Mount Allison University, Canada (B.Sc. Honors Physics; BA Asian Studies, French, Math), the Technical University of Denmark (M.Sc. Chemistry), the University of Southern Denmark (Ph.D. Physics), and Harvard University in the Department of Physics/Division of Engineering Applied Science and Brigham Women #39;s Hospital. In addition to her commitment to research, Rowat has also pioneered the use of examples from food and cooking as vehicles for teaching sophisticated physics concepts to a general audience. She is the co-developer of the first annual Harvard Science Cooking course, and is founder and director of Science Food, an organization based at UCLA that promotes knowledge of science through food and food through science. Rowat has published numerous articles and patents, and has received numerous honors and awards, including being named a Hellman Fellow and Human Frontiers Cross-Disciplinary Fellow. AboutTEDx, x = independently organized event In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark ...From:TEDxTalksViews:2 1ratingsTime:16:03More inScience Technology

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The Molecules We Eat: Amy Rowat at TEDxUCLA - Video

Motor rehabilitation using the Wii platform – Video

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Motor rehabilitation using the Wii platform
Motor rehabilitation using the Wii platform at the Laboratory of Rehabilitation Bioengineering in Volterra, Italy. Joint research lab between the BioRobotics Institute of Scuola Supeiore Sant #39;Anna (at Polo Sant #39;Anna Valdera in Pontedera, Italy) and "Auxilium Vitae" Rehabilitation Centre (Volterra, Italy).From:Stefano MazzoleniViews:2 0ratingsTime:00:20More inScience Technology

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Motor rehabilitation using the Wii platform - Video

ECE Illinois Alumni: Gale Beanblossom – Video

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ECE Illinois Alumni: Gale Beanblossom
The Department of Electrical and Computer Engineering has had many notable alumni in its long history. Here #39;s a short conversation with Gale Beanblossom (BS Bioengineering #39;80, MSEE #39;82), Senior Manager at The Boeing Company.From:Illinois1867Views:2 0ratingsTime:01:25More inEducation

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ECE Illinois Alumni: Gale Beanblossom - Video

Illinois Nano-Bio Node – BioE Seminar Series Nov. 8, 2012 – Medical Imaging System Design – Video

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Illinois Nano-Bio Node - BioE Seminar Series Nov. 8, 2012 - Medical Imaging System Design
Nov. 8, 2012. BioEngineering Seminar Series. University of Illinois Urbana-Champaign "Advances in the science of medical imaging system design" Michael F. Insana, Professor and Department Head, Bioengineering, UIUC Nghia Q. Nquyen, Sara Bahramian, Craig K Abbey,From:illinoisncnViews:7 0ratingsTime:56:02More inScience Technology

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Illinois Nano-Bio Node - BioE Seminar Series Nov. 8, 2012 - Medical Imaging System Design - Video