Tooth | anatomy | Britannica.com

Tooth, plural teeth, any of the hard, resistant structures occurring on the jaws and in or around the mouth and pharynx areas of vertebrates. Teeth are used for catching and masticating food, for defense, and for other specialized purposes.

The teeth of vertebrates represent the modified descendants of bony dermal (skin) plates that armoured ancestral fishes. A tooth consists of a crown and one or more roots. The crown is the functional part that is visible above the gum. The root is the unseen portion that supports and fastens the tooth in the jawbone. The root is attached to the tooth-bearing bonethe alveolar processesof the jaws by a fibrous ligament called the periodontal ligament or membrane. The neck of the root is embraced by the fleshy gum tissue (a specialized area of connective tissue covered with mucous membrane that lines the mouth cavity). The shape of the crown and root vary among different teeth and among different species of animals.

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human digestive system: The teeth

The teeth are hard, white structures found in the mouth. Usually used for mastication, the teeth of different vertebrate species are sometimes specialized. The teeth of snakes, for example, are very thin and sharp and usually curve backward; they function in capturing prey but

All true teeth have the same general structure and consist of three layers. In mammals an outer layer of enamel, which is wholly inorganic and is the hardest tissue in the body, covers part or all of the crown of the tooth. The middle layer of the tooth is composed of dentine, which is less hard than enamel and similar in composition to bone. The dentine forms the main bulk, or core, of each tooth and extends almost the entire length of the tooth, being covered by enamel on the crown portion and by cementum on the roots. Dentine is nourished by the pulp, which is the innermost portion of the tooth. The pulp consists of cells, tiny blood vessels, and a nerve and occupies a cavity located in the centre of the tooth. The pulp canal is long and narrow with an enlargement, called the pulp chamber, in the coronal end. The pulp canal extends almost the whole length of the tooth and communicates with the bodys general nutritional and nervous systems through the apical foramina (holes) at the end of the roots. Below the gumline extends the root of the tooth, which is covered at least partially by cementum. The latter is similar in structure to bone but is less hard than dentine. Cementum affords a thin covering to the root and serves as a medium for attachment of the fibres that hold the tooth to the surrounding tissue (periodontal membrane). Gum is attached to the adjacent alveolar bone and to the cementum of each tooth by fibre bundles.

Like most other mammals, humans have two successive sets of teeth during life. The first set of teeth are called primary, or deciduous, ones, and the second set are called permanent ones. Humans have 20 primary and 32 permanent teeth.

Primary teeth differ from permanent teeth in being smaller, having more pointed cusps, being whiter and more prone to wear, and having relatively large pulp chambers and small, delicate roots. The primary teeth begin to appear about six months after birth, and the primary dentition is complete by age 2 1/2; shedding begins about age 5 or 6 and is finished by age 13. The primary teeth are shed when their roots are resorbed as the permanent teeth push toward the mouth cavity in the course of their growth.

In humans the primary dentition consists of 20 teeth four incisors, two canines, and four molars in each jaw. The primary molars are replaced in the adult dentition by the premolars, or bicuspid teeth. The 12 adult molars of the permanent dentition erupt (emerge from the gums) behind the primary teeth and do not replace any of these, giving a total of 32 teeth in the permanent dentition. The permanent dentition is thus made up of four incisors, two canines, four premolars, and six molars in each jaw.

Incisor teeth are the teeth at the front of the mouth, and they are adapted for plucking, cutting, tearing, and holding. The biting portion of an incisor is wide and thin, making a chisel-shaped cutting edge. The upper incisors have a delicate tactile sense that enables them to be used for identifying objects in the mouth by nibbling. Next to the incisors on each side is a canine, or cuspid tooth. It frequently is pointed and rather peglike in shape and, like the incisors, has the function of cutting and tearing food.

Premolars and molars have a series of elevations, or cusps, that are used for breaking up particles of food. Behind each canine are two premolars, which can both cut and grind food. Each premolar has two cusps (hence the name bicuspid). The molars, by contrast, are used exclusively for crushing and grinding. They are the teeth farthest back in the mouth. Each molar typically has four or five cusps. The third molar in humans tends to be variable in size, number of roots, cusp pattern, and eruption. The number of roots for each type of tooth varies from one for incisors, canines, and premolars to two or three for molars.

The teeth of many vertebrates have been adapted for special uses. Rodents have curved incisors that are set deep in the jaws and which grow continually throughout life; hares and rabbits have similar teeth. The tusks of elephants are enlarged upper incisors. The tusks of the walrus are enlarged canines, as are those of the wild boar. In the pig the lower incisors lie close together and project forward to form a digging instrument. Baboons have enlarged canines for defense and display. Certain snakes have hollow teeth that function as needles to insert venom. The sawfish, the only animal with true teeth outside its mouth, uses the teeth on both sides of its snout to slash its prey. The forms, patterns, and arrangements of teeth in different species of animals are of great importance in determining their phylogenetic (taxonomic) relationships.

Caries, or tooth decay, is the most common disease of the teeth among humans. Apart from the common cold, it is perhaps the most frequent disease in contemporary society. Tooth decay originates in the buildup of a yellowish film called plaque on teeth, which tends to harbour bacteria. The bacteria that live on plaque ferment the sugar and starchy-food debris found there into acids that destroy the tooths enamel and dentine by removing the calcium and other minerals from them. Caries usually commences on surface enamel, especially in pits and fissures and between adjacent teeth. From the enamel the process of decay spreads to the underlying dentine, and may finally involve the tooth pulp. Aside from keeping the teeth clean through regular brushing and flossing, tooth decay can be greatly reduced by the addition of fluorides to drinking water. Caries is treated by removing decayed dental tissue and replacing it with inert filling substances.

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primate: Teeth

A dentition with different kinds of teeth (heterodonty)incisors, canines, and cheek teethis characteristic of all primates and indeed of mammals generally. Heterodonty is a primitive characteristic, and primates have evolved less far from the original pattern than most mammals. The principal changes are a

The teeth may be subject to certain irregularities in their alignment, such as an abnormality in the relationship between the teeth in opposing jaws (malocclusion). In a less-severe irregularity, one or more teeth may be out of alignment. Both types of problems are best treated early in life through the use of special fixed or removable appliances (i.e., braces).

Another common dental disorder is inflammation of the gum, or gingivitis. It usually commences at or close to the gum margin, often between adjacent teeth. Pockets form between the gum and the adjacent teeth, sometimes penetrating deeply into the tissues. This leads to further infection, with inflammation and bleeding from the infected gums. A principal cause of gingivitis is
the buildup of plaque on teeth, which causes irritation of the gums and thus leads to their inflammation and infection.

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‘Young Sheldon’, ‘Grey’s Anatomy’ Spinoff Among 13 U.S. Series Picked Up By CTV LA Screenings – Deadline

Canadian broadcast network CTV has picked up four new U.S. comedies and nine dramas from this years Los Angeles Screenings for the 2017-18 season.

They are comedies The Big Bang Theory spinoff Young Sheldon, Me, Myself & I from CBSandRoseanne revival and The Mayor from ABC. Dramas include Shondalands untitled Greys Anatomy spinoff, which will premiere midseason, and new legal drama For the People. Also on the list are new ABC dramas The Good Doctor, Ten Days in the Valley, The Crossing, Deception, The Gospel of Kevin and Marvels Inhumansalong with Foxs The Gifted.

CTV and CTV Twos 2017-18 primetime schedules will be unveiled at the CTV Upfront on June 7 in Toronto.

CTVs strategically curated mix of the years most-buzzed about sitcoms and compelling dramas sets the stage for viewers to root for both heroes, families and even misfits with heart, said Mike Cosentino, SVP Content and Programming atCTV parent company Bell Media. We cant wait to share our powerful new slate with advertisers and viewers next week.

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'Young Sheldon', 'Grey's Anatomy' Spinoff Among 13 U.S. Series Picked Up By CTV LA Screenings - Deadline

Spoiler Room: Scoop on Blindspot, Brooklyn Nine-Nine, Grey’s Anatomy, and more – EW.com (blog)

Welcome to the Spoiler Room, a safe place for spoiler addicts to come on a weekly basis to learn whats coming next on their favorite shows and, hopefully, get a few of their own questions answered. If you want scoop on a specific show, send your questions to spoilerroom@ew.com.

Anything new to tease for season 3 of Blindspot? TonyIf youre wondering what has happened to the team over the last 18 months thats the exact amount of time that has passed when we pick back up with Jane and Weller answers will come very quickly this season. Youll see flashbacks, EP Martin Gero promises. We hope to fill in a lot of it right away in the first two or three minutes of the show. No fan of the show will want to miss the opening of the season that will endeavor to fill in a lot of what the hell is going on. Why did she run away? Are Jane and Weller married? All those questions will be answered in the first few minutes.

How long will Jake and Rosa be in jail on Brooklyn Nine-Nine? JessicaIf Boyle has his way, not long! Hes determined to make sure that his friends innocence is known to the rest of the world, Joe Lo Truglio tells me. So hes doing everything he can, hes tailing Hawkins and hes trying to take advantage of her making a mistake. But expect to find a very different Boyle in Jakes absence when the show returns. Theyve got a wonderful cold open to show his depression, which rivals and dare I say surpasses him breaking up with Vivian in the Matrix leather coat cold open.

Where is the new season of Greys Anatomy picking up? KarolineRight where we left off, so everyone is still reeling in the wake of the finale explosion. But it wont be long before theres a shakeup at Grey Sloan. Theres obviously some damage to the hospital, Kelly McCreary says. But it is, in true Greys Anatomy style, a completely surmountable obstacle, because we are superhuman doctors. It serves more as a metaphor of the transformation that the show is going to go through tonally. Its lighter this season. The hospital definitely is undergoing some changes in the form of a new crop of students coming in. Itll look a bit different in certain areas, and some relationships have come to an end or are blossoming, so repairing the damage is more of a metaphor.

Any Chicago P.D. news would be great. MarAntonio is back in Intelligence, as a case in the premiere reconnects him with his former family. The suspect that theyre going after, they hit a bump in the road and they need someone to come in that this guy has never seen and can do a great job undercover, and thats where Antonio comes in, Jon Seda tells me, teasing that Antonio will bump heads with Voight over certain new policies within Intelligence this year.

Will Kuasa crossing paths with Ray on Vixen be addressed on Legends of Tomorrow? ColemanYes, and his knowledge of Kuasa just may help the Legends version of Vixen. If you go back and look at Vixen season 2, I wouldnt exactly call her fighting alongside Ray, shes always been morally questionable, EP Marc Guggenheim says. But I think thats what makes it interesting as far as Amaya is concerned is that Ray, at the appropriate moment, will accurately tell her that there were moments where Kuasa was capable of selfless good, so I think that gives Amaya a little bit of hope.

Do you know anything more about Reginas alter-ego on Once Upon a Time? BradenBar owner Roni is very, very different from Regina, so prepare yourselves. Shes given up a little bit on life, Lana Parrilla tells me. She seems a little hopeless when we first meet her, and then Henry comes to town and things start to shift a little bit. But dont expect his arrival to immediately spark Reginas memories. No, theres nothing there, and I like that. Shes just asleep. Shes not quite in touch with all that stuff yet. A few more things need to happen before she starts getting that feeling. Although, she is inspired by a character, and it shifts her a bit, at the end of the first episode.

Anything on the Hawaii Five-0 team in season 8? ElizabethI hear theres going to be another new member of the team but its definitely not who (or what!) youre expecting. There is a story thats coming up, it actually was Alex OLoughlins idea, EP Peter Lenkov says. I wanted to do a story where the victim left in the wake of a tragedy was a dog who lost its owner. Its a very emotional, really great story. Its a dog thats a drug sniffing service dog that McGarrett ends up adopting. Its a really emotional journey, but it was his idea to keep the dog, and I thought that was a great one.

Hand over some Scandal scoop! DangerWaveWith Cyrus sliding into the White House as VP to Mellies POTUS, Jake will somewhat be sidelined but his continued role in the White House will put some pressure on the dynamic between Jake and Olivia. The interesting thing for Jake is that hes still the head of the NSA, but Olivia being Chief of Staff is sort of his boss, which is a position theyve never really find themselves in and a dynamic we have yet to explore, Scott Foley says. Its going to cause some waves in the water of love.

How will Gretchen be handling Jimmys disappearing act on Youre the Worst this season? MalloyNot well. Not well at all. Believe me, Gretchen does something so shocking in the premiere and enlists Lindsay to do it, too that you will have to remind yourself of the title of the show before you fall down a rabbit hole. And it only gets worse from there. Theres some weird sh that goes down, Aya Cash says. There are so many different kinds of bad, let me put it that way. Even so, Cash has hopes that Gretchen and Jimmy will eventually reconcile. I do because this show is about them and theyre going to have to figure it out, she says. I feel like were heading toward something positive. They start to work out how to be around each other and how to engage in a healthier way. But will she get payback on Jimmy for abandoning her? Yes, Cash says with a smirk.

Any scoop on the season finale of Shadowhunters? TaylorA. lot. happens. Youll find out whether weve seen the last of Jonathan within the finales first minute, but regardless of what happens there, theres still the matter of stopping Valentine. And lets just say that battle is filled with big decisions for Clary, none of which shell be able to take back, and the consequences of which will play heavily into next season. That cryptic enough?

This week in TV: TCA is finally over! You can read all the coverage from our incredibly hard-working TV team here.

Thats a wrap on this weeks Spoiler Room. Be sure to email your questions to spoilerroom@ew.com or tweet them to @NatalieAbrams.

Additional reporting by Samantha Highfill.

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Spoiler Room: Scoop on Blindspot, Brooklyn Nine-Nine, Grey's Anatomy, and more - EW.com (blog)

‘Grey’s Anatomy’ Roundup: Who’s Leaving, Who Has a Budding Romance and Why the Show Is Going Back to Its … – BuddyTV (blog)

'Grey's Anatomy' Roundup: Who's Leaving, Who Has a Budding Romance and Why the Show Is Going Back to Its Roots for Season 14Wednesday, September 06, 2017

Who's Out of Grey Sloan?

Going Back to Its Roots

Grey's Anatomy will be welcoming backKrista Vernoff, who wrote and executive produced the series for its first eight seasons. The return of Vernoff is expected to bring back some much-needed levity.

"We're touching base in a meaningful way with where we left off with all the characters from last season and to contain that much story in two hours, you have to keep it light, bouncy and fun -- and Krista Vernoff brings that shift to the show," added Kelly McCreary (Maggie).

"It's funnier, it's sexier, it's lighter," Gianniotti said. "We're going to have fun this season. There's just been a lot of separation and loss, so we want to show the characters having some fun. Also, a lot of the men are single now, so we're going to explore what that dynamic is like."

A Budding Romance

The season 13 finale seemingly paved the way for a potential new romance between Maggie and Jackson -- courtesy of April, who took notice of the connection. This leaves plenty of questions not just among fans but for the characters involved as well. While it's not yet safe to assume a April-Jackson-Maggie love triangle, Maggie (at least) will be dealing with April's truth bomb.

What's In Store for Jo?

The past several seasons have been tough on Jo but she may finally catch a break in season 14. Apart from exploring her domestic violence storyline, love may be in the cards for her as well.

"This season Jo may feel inspired by someone again," added the actress, who has heard Jo may find a new mentor in Season 14.

And now that her best friend Stephanie (Jerrika Hinton) is no longer around, she may find someone else to lean on.

Eric Dane Reveals He's Only Watched Three Episodes of Grey's Anatomy

Eric Dane may have played Dr. Mark Sloan on Grey's Anatomy for six seasons but that doesn't mean he's an avid fan who religiously watches the ABC series. In fact, he's only seen three episodes during his time on the show.

That doesn't mean, however, that he doesn't keep in touch with some of his Grey's Anatomy co-stars. "Shonda's great," said Dane, who is currently starring on The Last Ship. "I'm still friends with her to this day. One thing that you do with Shonda is that you don't deviate. That's one of the biggest lessons you learn, is that you stick to the script."

Deleted Scene RevealsCatherine Almost Sidelined Bailey over Karev's Assault

Meanwhile, here's a peek at the fall promo for ABC's Thursday lineup, which features Shonda Rhimes' Grey's Anatomy, Scandal and How to Get Away with Murder.

(Image courtesy of ABC)

Will Jo and DeLuca Get Together on Grey's Anatomy?>>>

Who's Out of Grey Sloan?

Going Back to Its Roots

Grey's Anatomy will be welcoming backKrista Vernoff, who wrote and executive produced the series for its first eight seasons. The return of Vernoff is expected to bring back some much-needed levity.

"We're touching base in a meaningful way with where we left off with all the characters from last season and to contain that much story in two hours, you have to keep it light, bouncy and fun -- and Krista Vernoff brings that shift to the show," added Kelly McCreary (Maggie).

"It's funnier, it's sexier, it's lighter," Gianniotti said. "We're going to have fun this season. There's just been a lot of separation and loss, so we want to show the characters having some fun. Also, a lot of the men are single now, so we're going to explore what that dynamic is like."

A Budding Romance

The season 13 finale seemingly paved the way for a potential new romance between Maggie and Jackson -- courtesy of April, who took notice of the connection. This leaves plenty of questions not just among fans but for the characters involved as well. While it's not yet safe to assume a April-Jackson-Maggie love triangle, Maggie (at least) will be dealing with April's truth bomb.

What's In Store for Jo?

The past several seasons have been tough on Jo but she may finally catch a break in season 14. Apart from exploring her domestic violence storyline, love may be in the cards for her as well.

"This season Jo may feel inspired by someone again," added the actress, who has heard Jo may find a new mentor in Season 14.

And now that her best friend Stephanie (Jerrika Hinton) is no longer around, she may find someone else to lean on.

Eric Dane Reveals He's Only Watched Three Episodes of Grey's Anatomy

Eric Dane may have played Dr. Mark Sloan on Grey's Anatomy for six seasons but that doesn't mean he's an avid fan who religiously watches the ABC series. In fact, he's only seen three episodes during his time on the show.

That doesn't mean, however, that he doesn't keep in touch with some of his Grey's Anatomy co-stars. "Shonda's great," said Dane, who is currently starring on The Last Ship. "I'm still friends with her to this day. One thing that you do with Shonda is that you don't deviate. That's one of the biggest lessons you learn, is that you stick to the script."

Deleted Scene RevealsCatherine Almost Sidelined Bailey over Karev's Assault

Meanwhile, here's a peek at the fall promo for ABC's Thursday lineup, which features Shonda Rhimes' Grey's Anatomy, Scandal and How to Get Away with Murder.

(Image courtesy of ABC)

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'Grey's Anatomy' Roundup: Who's Leaving, Who Has a Budding Romance and Why the Show Is Going Back to Its ... - BuddyTV (blog)

Anatomy of a bowling ball: How Storm Products makes balls in Brigham City – Standard-Examiner

Like the wheel, it might seem like theres no re-inventing a ball, but the minds at Storm Products, Inc. have been doing it for decades.

Theres more to high-performance bowling balls than meets the eye. Theyre designed for all kinds of skill, style and conditions. Tavio Sawyer, Storms creative director, compares them to golf clubs.

Like golf clubs, (serious) bowlers have more than one ball they carry, he said.The lane is like a fairway or the green it changes.

RELATED: Brigham-based bowling ball maker looks for new market

To understand the nuances of ball technology and how theyre built to perform in different ways, it helps to peek inside.

Core

At the heart of the ball is its weight block, which varies in size and shape. Some look like lightbulbs, some look like fishing reels, some look like spinning tops. Others are completely symmetrical and round.

The weight blocks drive how the ball performs how and when it curves or hooks, how fast it revs and where it rotates on the balls axis.

Thats the idea of the shapes, said Chad McLean, Storms technical staff manager.Then all these nooks, crannies and different things make the ball do something different.

Bowlers select different cores to match their throwing style and for spare balls when they need to throw at different angles.

The weight block is the balls core. Some are wrapped in a white cover material, some blocks are wrapped directly in the cover stock.

Cover stock

The cover stock is the part of the ball you see. In the early days, balls were made of wood. By the early 1900s, they were made of rubber. Now theyre mostly made of resins and urethane, although free house balls provided at bowling centers are made of plastic.

Cover stock comes in a variety of colors and finishes. Storm infuses theirs with different scents, like birthday cake, strawberry lemonade and caramel pecan.

A bowler picks cover stock colors and smell to meet her taste, but finishes have a more specific purpose. They have a microscopic tread meant to handle different oil conditions on the bowling lane.

Sawyer compares the core to a cars engine and the cover stock to tires.

The engine makes it move, but the tires help cut through the oil, he said. If you have no polish, its going to absorb more oil if oil on the lane gets really heavy, instead of throwing this thing thats going to hydroplane, you want something that will cut through the oil ... so that when it gets to the part in which a ball needs to hook, the ball still has enough power to do that.

Oil conditions vary from lane to lane and the amount of traffic a lanes seen. Experienced bowlers know how to read the lanes and select the right ball for oil conditions.

Holes

Pro shops drill custom finger holes to fit a bowlers hand. Those finger holes are placed on different parts of the ball, depending on the bowlers style.

Where you put holes in relationship to core inside makes that ball unique, McLean said. You can have three of the same exact ball, but put the holes in different spots, and youre going to have three different balls.

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Anatomy of a bowling ball: How Storm Products makes balls in Brigham City - Standard-Examiner

Anatomy and physiology of ageing 5: the nervous system – Nursing Times

Download a print-friendly PDF file of this article here

John Knight is senior lecturer in biomedical science; Yamni Nigam is associate professor in biomedical science, both at the College of Human Health and Science, Swansea University.

The nervous system controls the activities of all body organs and tissues, receiving input from sensory organs and responding via effector organs. With around 100billion interconnected neurons, the brain is an extremely complex, and still poorly understood, organ. However we do understand, to some degree, how age affects it, as well as the nervous system as a whole. This fifth article in our series on the anatomy and physiology of ageing describes the age-related changes occurring in the brain, spinal cord and peripheral nerves. These changes lead to a gradual decline in cognitive function and a range of other issues, such as reduced bladder control or postural hypotension, but in health the brain normally continues to function adequately throughout life.

Knight J, Nigam Y (2017) Anatomy and physiology of ageing 5: the nervous system. Nursing Times [online]; 113: 6, 55-58.

The nervous system, along with the endocrine system, controls and integrates the activities of all the bodys organs and tissues. It receives and processes sensory input from organs such as the eyes, ears and skin, and responds through a variety of effector organs.

The main organ of the nervous system is the brain, which, with around 100billion interconnected neurons, is extremely complex; despite decades of research, its function remains poorly understood. Ageing leads to a progressive loss of neurons and depletion of neurotransmitters (Mather, 2016), these changes are usually associated with a gradual decline in cognitive function and influenced by environmental, genetic and lifestyle factors (Nyberg et al, 2012).

The ageing brain gradually loses neurons and supporting neuroglial cells (Fig 1). Between the ages of 20 and 60, the brain loses around 0.1% of neurons per year, after which the process speeds up (Esiri, 2007). By the age of 90, brain mass will have decreased by around 11% compared with individuals in their 50s, which equates to a loss of about 150g of neural tissue (Wyss-Coray, 2016). The remaining tissues harbour an increased concentration of potentially harmful materials such as iron, aluminium and free radicals.

Aged neural tissues also show increasing pigmentation, largely due to the deposition of two pigments: one brown, lipofuscin (Ottis et al, 2012), and one black, neuromelanin (Clewett et al, 2016). Lipofuscin is linked to amyloid

protein deposition and the formation of neurofibrillary tangles. These abnormal areas of neural tissue are often present at low densities in aged brain tissue, even in the absence of disease (Wyss-Coray, 2016); however, where Alzheimers disease is present, these are at high densities.

The loss of neurons is most apparent in the cerebral cortex. The grooves (sulci) that mark the surface convolutions (gyri) of the cerebral cortex are visibly deeper in brains of older people (Fig 1). It was originally thought that the frontal lobes were particularly vulnerable to neural loss, but similar losses have been observed in other cortical regions such as the parietal lobes (Fjell et al, 2014).

Fig 1. Three age-related changes in the brain

Fig 1. Three age-related changes in the brain

Structural changes in the frontal and parietal lobes are related to poor memory. Many people in their 80s have modest levels of amyloid protein deposition and retain their memory, while individuals with higher levels typically have a poorer working (short-term) memory (Nyberg et al, 2012). However, the role of amyloid deposition in impairing memory has recently been questioned and other factors, such as accumulation of tau proteins, may play a more important role (Brier et al, 2016).

The hippocampus has a key role in memory and the acquisition of new skills. With age, it loses a significant amount of neural tissue (Burke and Barns, 2006), which may explain why activities such as learning a new language become more difficult with advancing age. Recent research indicated that navigating a computer-generated virtual environment improved spatial awareness and reduced the shrinkage of the hippocampus, both in younger and older people (Lvdn et al, 2012). Virtual reality computer programs could therefore potentially be used to reduce shrinkage in this vital brain area.

Around 35% of people over the age of 70years have gait problems; while there are many contributing factors, including age-related changes to muscles and joints, the nervous system is also implicated. The somatic motor cortex located in the frontal lobes of the brain controls the movement of muscles involved in walking. From middle age onwards the neurons in this region show signs of atrophy (Manini et al, 2013), which can contribute to gait problems, potentially reducing mobility in older people (Rosso et al, 2013).

Ageing is associated with a gradual increase in the size of the ventricles (fluid-filled chambers) in the brain (Fig 1). This is likely to result from a progressive loss of the cells that line the ventricles. Enlarged ventricles fill with more cerebrospinal fluid, and are readily observable using techniques such as magnetic resonance imaging. On average, the volume of the ventricular system increases by around 2.9% per year; this expansion appears to accelerate with age, with people over the age of 70 having a median rate of expansion of 4.25% per year (Raz and Rodrigue, 2006). Although ventricular expansion is seen in most older people, the cognitive impact of this remains unclear.

The medulla oblongata and other areas of the brainstem lose fewer neurons than other regions of the brain. The brainstem is probably the best preserved region of the brain, which probably reflects its essential role in supporting life: it controls breathing, peristalsis, heart rate and blood pressure. However, the autonomic function of the brain does decline with age and this can compromise the bodys ability to respond quickly to internal and external environmental changes (Hotta and Uchida, 2010). Both branches of the autonomic nervous system (ANS) the parasympathetic and sympathetic branches are compromised with age (Parashar et al, 2016).

These changes can negatively affect older people. For example, the blunting of baroreceptor responses increases the risk of postural hypotension, so standing up suddenly can lead to falls and injury. Another negative consequence is the gradual loss of bladder control. To control micturition, the body relies on the interplay of sensory stretch receptors and the ANS (which together monitor bladder filling) and the conscious areas of the cerebral cortex (which signals when the bladder is full). To initiate micturition, the body needs motor control of the urinary sphincter. All these elements function less well with age, and these age-related changes combine with those in other body systems such as prostate enlargement in men and weakened pelvic floor muscles in women to reduce bladder sensitivity and control (Hotta and Uchida, 2010), which can lead to continence problems.

Cerebral blood flow decreases by around 0.38% per year, equating to a 27% decline over 70years of life (Chen et al, 2011). This is a direct consequence of the age-related changes in the cardiovascular system, and may be exacerbated in patients with atherosclerotic occlusion of the carotid arteries.

The blood-brain barrier (BBB) is formed primarily of tight junctions between adjacent endothelial cells within the blood vessels in the brain. Additionally, specialised neuroglial cells called astrocytes wrap around the cerebral vessels, forming a further physical barrier between the blood and neural tissues. The BBB is essential to prevent most pathogens and many toxic materials crossing into the neural networks and pathways of the brain, but its integrity appears to diminish with ag
e. A recent study indicates that, during normal ageing, the BBB is first weakened in the hippocampus, thereby allowing harmful substances and pro-inflammatory mediators to cross into this vital region of learning and memory. This breaching of the BBB may contribute to hippocampal shrinkage, and therefore to cognitive decline (Montagne et al, 2015).

Ageing is associated with a declining production of many neurotransmitters, including noradrenaline, glutamate, dopamine and serotonin. The decline in dopamine appears to be particularly important: dopamine modulates motor function and the acquisition of new skills, while also acting as one of the brains reward chemicals (Mather, 2016). The number of dopamine-producing neurons decreases as part of the normal ageing process, and this can adversely affect the ability to learn from past experiences. Recent studies show that many older people who boosted their levels of dopamine by taking L-DOPA (a drug normally used to treat Parkinsons disease) were learning as quickly as young adults again (Chowdhury et al, 2013).

Few studies have examined age-related changes to the spinal cord. A recent animal-model study shows an increase of cholesterol content in the ageing spinal cord, and the authors suggest this may potentially impair cord function (Parkinson et al, 2016).

Age-related changes to neurons and neuroglial cells appear to have little effect on spinal cord function. However, age-related changes to the vertebrae and intervertebral discs may increase pressure on the spinal cord and its branching nerve roots. This can slow down the conduction of nerve impulses along motor neurons, contributing to reduced muscular strength (Manini et al, 2013). Reduced sensory and motor conduction will increase the risk of injury due to poor coordination, poor balance and poor fine motor control.

With age, some peripheral neurons show a dying back (shrinkage of axonal length), loss of mitochondria and a degeneration of their insulatory myelin sheaths. Some of this damage may be caused by a rise in the concentrations of pro-inflammatory mediators in the body. The ageing body becomes less effective in clearing toxic metabolites and, as peripheral nerves are not afforded the protection of the BBB, this may contribute to peripheral nerve damage (Manini et al, 2013).

The loss of myelin slows the conduction of peripheral nerve impulses by around 5-10% (Joynt, 2000). In health, this reduction in conductivity causes few problems, but in older people with diabetes it may contribute to, and exacerbate, diabetic neuropathy. Damaged peripheral nerves are not repaired as efficiently in older people as in their younger counterparts, and some of these nerves are never repaired. This can contribute to reduced sensation and motor control.

In the absence of disease, intellectual ability can be retained throughout life. However, the gradual loss of neurons, depletion of neurotransmitters and slowing of nerve conduction may act together to slow down the processing of information. As a result, older people may take longer to complete certain tasks, and commonly experience the functional brain changes described below.

The loss of short-term and episodic memory is probably the earliest indication of age-related changes in the brain. Unlike what happens in dementia, the loss of short-term memory in the absence of disease does not affect life skills (such asthe ability to cook), but manifests as inconveniences (such as forgetting an item from the shopping list). Episodic memory (that is, remembering autobiographical events and their timings and sequence) also gradually declines in many older people (Fjell et al, 2014).

Verbal communication skills generally remain strong throughout life (Park and Reuter-Lorenz, 2009), but people over the age of 70years may have increasing problems using or recalling words. The ability to quickly name a common object usually remains stable up to the age of 70, but then declines with advancing years (Harada et al, 2013).

The progressive loss of neurons, reduction in impulse velocity and minor changes in the spinal cord lead to a slowing down of reaction times (Spirduso, 1995). This can create problems, particularly when a fast reaction is essential (for example, to step out of the way of oncoming traffic).

In England, around 22% of men and 28% of women over the age of 65 are affected by depression; in care homes, the figures are even greater, with around 40% of residents affected (Age UK, 2017).

It is almost impossible to determine whether depression in older people occurs as a normal consequence of ageing or as a result of chemical imbalances seen in types of depression that also affect younger people. Concentrations of neurotransmitters involved in lifting mood (particularly serotonin) diminish with age and this can contribute to symptoms of depression (Fidalgo et al, 2013). The Royal College of Psychiatrists estimates that >85% of depressed older people receive no help from the NHS (Age UK, 2017). Depression can often produce symptoms that mimic dementia (pseudo-dementia) and this often causes great anxiety.

On the whole, older people are less prone to emotional outbursts than younger people. This may be related to the relative structural stability of some of the brain regions linked to emotions. Most studies of the amygdalae which are heavily involved in impulsive behaviours and emotional reactions reveal little evidence of atrophy or shrinkage at a much slower rate than in other brain regions. Additionally, the amygdalae also appear to retain most of their functional activity in older age (Mather, 2016).

Because the overall neural mass reduces with age, neuroactive drugs such as antidepressants and neuroleptics can be more potent in older people. Doses normally prescribed to adults may induce confusion or delirium, and may therefore need to be adjusted.

How normal age-related changes to the brain can be distinguished from pathological changes associated with dementia (for example, Alzheimers disease) is hotly debated. The problem is that three of the main clinical features of Alzheimers disease loss of episodic memory, loss of brain tissue and amyloid deposition are also seen in apparently healthy older people with little or no evidence of dementia. However, it is generally recognised that the main risk factor for developing dementia is advancing age (Fjell et al, 2014).

Unlike cells in many other parts of the human body, most neurons do not undergo cell division so, when they dieas a result of age or injury, they are generally not replaced. Fortunately, the brain contains over 100billion interconnected neurons (the connectome) and many researchers agree that it has an in-built redundancy, known as the brain reserve. This is defined as the physical resources of the brain in terms of brain mass and number of neurons; a larger brain reserve is often associated with better outcomes after brain injury and in various neurological diseases (Tucker and Stern, 2011).

The brain reserve is not necessarily a good predictor of cognitive function (many people with normal cognition have significant brain atrophy), so the concept of cognitive reserve has emerged. People with a high cognitive reserve are able to use their brain reserve more efficiently to perform tasks, and this seems to happen through increased efficiency of functional connections between neurons (Marques et al, 2016).

Good predictors of a high cognitive reserve include high education level, high IQ, highly complex occupation and large amount of social interaction. Recent research indicates that cognitive ability may also be maintained by neural compensation, a process in which new circuits of neurons are recruited to perform tasks that were once carried out by aged ordamaged neural pathways (Steffener and Stern, 2012). In normal ageing, the brain reserve does decline but cognition ismaintained thanks to the brains in-built redundancy.

Keeping mentally active throughout life can reduce the effects of age on th
e nervous system (Mahncke et al, 2006), and engaging in social, sporting and mentally challenging activities can slow downthe decline in cognitive performance (Nyberg et al, 2012). It appears the more intellectually demanding and complex an individuals occupation, the better their cognitive performance in later years; however, in retirement, when the mental challenges of work are removed, this effect appears to decline.

Older people should be encouraged to engage in stimulating activities such as socialising, reading and games, which are thought to improve cognitive function and memory, as well as reduce the riskof depression. It is a common misconception that ageing naturally leads to conditions such as confusion, dementia and delirium. The human brains in-built redundancy allows it to adequately cope with the physical changes associated with ageing. Indeed, in the absence of disease, adequate mental function can be retained throughout life.

Age UK (2017)Later Life in the United Kingdom, January 2017.London: Age UK.

Brier MR et al (2016) Tau and A imaging, CSF measures, and cognition in Alzheimers disease.Science Translational Medicine;8: 338, 338ra66.

Burke SN, Barnes CA (2006) Neural plasticity in the ageing brain.Nature Reviews Neuroscience;7: 1, 30-40.

Chen JJ et al (2011) Age-associated reductions in cerebral blood flow are independent from regional atrophy.Neuroimage;55: 2, 468-478.

Chowdhury R et al (2013) Dopamine restores reward prediction errors in old age.Nature Neuroscience;16: 5, 648-653.

Clewett DV et al (2016) Neuromelanin marks the spot: identifying a locus coeruleus biomarker of cognitive reserve in healthy aging. Neurobiology of Aging; 37: 117-126.

Esiri MM (2007) Ageing and the brain. Journal of Pathology; 211: 2, 181-187.

Fidalgo S et al (2013) Serotonin: from top to bottom. Biogerontology; 14: 1, 21-45.

Fjell AM et al (2014) What is normal in normal aging? Effects of aging, amyloid and Alzheimers disease on the cerebral cortex and the hippocampus. Progress in Neurobiology; 117: 20-40.

Harada CN et al (2013) Normal cognitive aging; Clinics in Geriatric Medicine; 29: 4, 737-752.

Hotta H, Uchida S (2010) Aging of the autonomic nervous system and possible improvements in autonomic activity using somatic afferent stimulation. Geriatrics and Gerontology International; 10: Suppl 1, S127-S136.

Joynt RJ (2000) Aging and the nervous system. In: The Merck Manual of Geriatrics. West Point PA: Merck & Co.

Lvdn M et al (2012) Spatial navigation training protects the hippocampus against age-related changes during early and late adulthood. Neurobiology of Aging; 33: 3, 620.e9-620.e22.

Mahncke HW et al (2006) Memory enhancement in healthy older adults using a brain plasticity-based training program: a randomized, controlled study. Proceedings of the National Academy of Sciences of the United States of America; 103: 33, 12523-12528.

Manini TM et al (2013) Aging and muscle: a neurons perspective. Current Opinion in Clinical Nutrition and Metabolic Care; 16: 1, 21-26.

Marques P et al (2016) The functional connectome of cognitive reserve. Human Brain Mapping; 37: 9, 3310-3322.

Mather M (2016) The affective neuroscience of aging. Annual Review of Psychology; 67: 213-238.

Montagne A et al (2015) Blood-brain barrier breakdown in the aging human hippocampus. Neuron; 85: 2, 296-302.

Nyberg L et al (2012) Memory aging and brain maintenance. Trends in Cognitive Sciences; 16: 5, 292-305.

Ottis P et al (2012) Human and rat brainlipofuscin proteome. Proteomics; 12: 15-16, 2445-2454.

Parashar R et al (2016) Age related changes in autonomic functions. Journal of Clinical and Diagnostic Research; 10: 3, CC11-CC15.

Park DC, Reuter-Lorenz P (2009) The adaptive brain: aging and neurocognitive scaffolding. Annual Review of Psychology; 60: 173-196.

Parkinson GM et al (2016) Perturbed cholesterol homeostasis in aging spinal cord. Neurobiology of Aging; 45: 123-135.

Raz N, Rodrigue KM (2006) Differential aging of the brain: patterns, cognitive correlates and modifiers. Neuroscience and Biobehavioral Reviews; 30: 6, 730-748.

Rosso AL et al (2013) Aging, the central nervous system, and mobility. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences; 68: 11, 1379-1386.

Spirduso WW (1995) Physical Dimensions of Aging. Champaign, Il: Human Kinetics.

Steffener J, Stern Y (2012) Exploring the neural basis of cognitive reserve in aging. Biochimica et Biophysica Acta; 1822: 3, 467-473.

Tucker AM, Stern Y (2011) Cognitive reserve in aging. Current Alzheimer Research; 8: 4, 354-360.

Wyss-Coray T (2016) Ageing, neurodegeneration and brain rejuvenation. Nature; 539: 7628, 180-186.

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Anatomy and physiology of ageing 5: the nervous system - Nursing Times

Anatomy of a SpaceX launch – USA TODAY

By Frank Pompa, Ramon Padilla, Mitchell Thorson USA TODAY

March 30, 2017

SpaceX will attempt to make history Thursday night by reusing a rocket booster. The Falcon 9 rocket will deliver a communications satellite into orbit using a first-stage system that they used nearly a year ago. Heres a look at SpaceXs feat to launch and land the system back on Earth.

The Falcon 9 is a two-stage rocket used to transport satellites and the Dragon spacecraft into orbit.

Aluminum-lithium alloy tanks fuel nine Merlin engines with liquid oxygen and rocket-grade kerosene propellant, generating more than 1.7 million pounds of thrust.

The main engines are cutoff as Falcon 9 nears the edge of Earths atmosphere.The total burn time from launch is 162 seconds.

Once beyond Earths atmopshere, the pneumatic stage separation system releases the first stage from the second stage. A single Merlin engine fires, propelling stage two into orbit.

The fairing separates from the second stage,exposing the satellite. Merlin engines ignite on the first stage, setting it on a trajectory for the landing site.

The second stage releases the satellite into a predetermined orbit.

The first stage undergoes a flip maneuver using onboard cold gas thrusters. When complete, it is positioned with engines forward.

The first stage grid fins deploy and engines do a temporary burn to slow it down. The grid fins will steer stage one as it enters Earths atmosphere.

Landing legs deploy and engines light a final time to land the first stage safely on a designated landing platform.

Source: SpaceX

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Anatomy of a SpaceX launch - USA TODAY

‘Big Bang Theory’ adjusts up; ‘Grey’s Anatomy,’ ‘Scandal,’ ‘Mom,’ ‘Powerless’ down: Thursday final ratings – TVbytheNumbers

Final broadcast primetime live + same-day ratings for Thursday, March 30, 2017

The Big Bang Theory adjusted up from its initial rating Thursday, but the 0.1 uptick to a 2.6 still puts it at a series low.

Several shows adjusted down. ABCs Greys Anatomy (2.0) and Scandal (1.5) came down a tenth of a point, although both are still ahead of last week. Mom (1.2) and Powerless (0.5) also adjusted down a tenth, as did a Superstore rerun (0.6).

Upward adjustments in adults 18-49 are in blue; downward adjustments are in red.

Network averages:

Definitions: Rating: Estimated percentage of the universe of TV households (or other specified group) tuned to a program in the average minute. Ratings are expressed as a percent. Fast Affiliate Ratings: These first national ratings are available at approximately 11 a.m. ETthe day after telecast. The figures may include stations that did not air the entire network feed, as well as local news breaks or cutaways for local coverage or other programming. Fast Affiliate ratings are not as useful for live programs and are likely to differ significantly from the final results, because the data reflect normal broadcast feed patterns. Share (of Audience):The percent of households (or persons) using television who are tuned to a specific program, station or network in a specific area at a specific time. Time Shifted Viewing:Program ratings for national sources are produced in three streams of data Live, Live +Same-Day and Live +7 Day. Time-shifted figures account for incremental viewing that takes place with DVRs. Live+SD includes viewing during the same broadcast day as the original telecast, with a cut-off of 3 a.m. local time when meters transmit daily viewing to Nielsen for processing. Live +7 ratings include viewing that takes place during the 7 days following a telecast.

Source: The Nielsen Company.

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'Big Bang Theory' adjusts up; 'Grey's Anatomy,' 'Scandal,' 'Mom,' 'Powerless' down: Thursday final ratings - TVbytheNumbers

‘Grey’s Anatomy’ Fans Aren’t Happy About That Shocking Sex Scene: Here’s Why – Us Weekly

Do not disturb! One of this season's most memorable Grey's Anatomy moments has undoubtedly been Jackson Avery (Jesse Williams) and April Kepner (Sarah Drew) getting frisky in a hotel hallway during the Thursday, March 16, episode. But the surprise hookup was not exactly a happy turn of events for all fans. Relive the steamy scene our video recap above!

Slowly Reconnecting

The ABC medical drama dropped hints throughout that episode that Jackson and April were going to get back together during their trip to Montana. Indeed, the couple were shown FaceTiming their daughter and collaborating to plan a surgery, with the procedure proving to be a success in more ways than one.

The surgeons accomplished a tough operation that had never been done before on a young girl with a throat tumor. Even though they have been constantly bickering in recent episodes, they actually came together to save a life. We did it, Jackson told his ex after they teamed up to perform a risky operation on a young girl with a throat tumor.

The Hotel Heats Up

Following surgery, the two were about to part ways to rest in their separate hotel rooms. However, the small talk they exchanged in the hallway suggested they had another activity in mind for the evening.

Im just thinking about our track record in hotel rooms, Jackson said as he approached his former wife. They started making out right there in the hallway, and Jackson didnt waste time before carrying April back to his hotel room. The next morning, the two were cuddling on the hotel bed sans clothes.

Sure, plenty of Greys fans were delighted by the twist, but others remain convinced that the reunion was a total mistake and that this won't end well, given the pair's rocky history. (The two doctors did not interact in the March 23 episode.)

Check out the tweets below about the controversial rendezvous.

Tell Us: Do you think the hookup was a mistake?

Grey's Anatomy airs on ABC Thursdays at 8 p.m. ET.

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'Grey's Anatomy' Fans Aren't Happy About That Shocking Sex Scene: Here's Why - Us Weekly

Station 19/Greys Anatomy: Jackson and Vic just arent right for each other – Hidden Remote

Station 19 andGreys Anatomyis attempting a crossover relationship with Jackson and Vic. However, things arent going to work if theyre not willing to compromise. I have a feeling this relationship is over before its even really begun.

TV crossover relationships can find it hard to work out. Its difficult to get the actors to pop up in the other shows when theyre not technically contracted for them. This could be a behind-the-scenes reason to bring this relationship to an end. But at the same time, the two characters are a world apart.

A huge problem with the two is that they arent communicating. In the early stages of dating, youre going to make decisions by yourself. However, those that affect the future with someone need to be communicated with the person youre dating.

Vic rushed straight into living with Dean during the last episode ofStation 19.After being evicted from her apartment, she tried to secretly live with Jackson but that didnt work. So, shes not living with Dean and helping him raise Pru (short for Pruitt to honor Captain Pruitt). Its great for her current situation, but she didnt quite think of a certain someone: Jackson.

At no point did she even consider running this idea by him. He was just going to have to deal with it.

Yet, he knows just how much hard work raising a baby is. He knows what its going to be like trying to steal a few moments with Vic. This is a huge decision that will affect Vic for the rest of her life, but she hasnt even considered talking to Jackson about it.

GREYS ANATOMY Jump into the Fog As fog begins to cover Seattle, the doctors of Grey Sloan navigate through personal complications. Meredith and Alex attempt to save Gus, while Levi talks some sense into a struggling Nico, on the season finale of Greys Anatomy, THURSDAY, MAY 16 (8:00-9:01 p.m. EDT), on The ABC Television Network. (ABC/Tony Rivetti)JESSE WILLIAMS

Jackson pointed out that Vic hasnt even met Harriet yet. And while that is partially because Jackson hasnt given her the chance, its a huge sign that this relationship isnt going to work. Harriet is a huge part of Jacksons life and he hasnt even considered introducing his new girlfriend to her.

Yes, this is a big step. The two are still in the early stages of a relationship, but it doesnt even look like Vic is all that interested in meeting Harriet just yet.

The only reason Jacksons daughter has been brought up is because Vic moved in to help Dean with Pru. Had that not happened, when would this conversation have happened?

I used to love Jackson. He is kind to his patients and tries to do the right thing. A major problem for him is just not being happy in a relationship. He jumps between girlfriends far too much.

He breaks up with Stephanie at Aprils wedding to run away with April. In fact, he doesnt even break up with Stephanie. Just a quick apology to her before he blow up April and Matthews wedding.

When April grieved for Samuel in her way through helping others, Jackson couldnt deal with it. He struggles with women trying to handle their own emotions and take control of their life. Granted, April probably didnt handle things all that well, but she was grieving too. The parents needed to talk to each other about their grief but neither of them felt the ability to.

Jackson moved on with Maggie and when things got hard there, they broke up. He moved on with Vic. And now things are getting hard. Things are getting real. Jackson just cant deal with it.

Until he learns how to commit and deal with the problems, hes not ready for a serious relationship. Its time for him to admit that now.

I thought Jackson and Maggie together was bad, but Jackson and Vic is becoming a trainwreck of a relationship. They just dont work.

What do you think about Jackson and Vic? Is it time for Jackson to be single for a good long while? Share your thoughts in the comments below.

Station 19 airs on Thursdays at 8/7c on ABC followed byGreys Anatomy.Catch up with both on Hulu.

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Station 19/Greys Anatomy: Jackson and Vic just arent right for each other - Hidden Remote

"Grey’s Anatomy" and other shows are donating necessary medical supplies during coronavirus crisis – CBS News

Television shows are donating medical supplies to real-life emergency personnel who need them in the fight against the coronavirus pandemic. The coronavirus outbreak in the United States has led to a nationwide shortage of medical supplies and calls for donations of items necessary to treat patients.

"Grey's Anatomy" has stepped up to provide gloves and gowns, while "Station 19" is donating N95 masks to the City of Ontario Fire Department and a firehouse in Los Angeles, an ABC spokesperson confirmed to CBS News.

"At 'Station 19,' we were lucky enough to have about 300 of the coveted N95 masks which we donated to our local fire station," Krista Vernoff, executive producer of both shows, said in a statement. "They were tremendously grateful. At Grey's Anatomy, we have a backstock of gowns and gloves which we are donating as well."

"We are all overwhelmed with gratitude for our healthcare workers during this incredibly difficult time, and in addition to these donations, we are doing our part to help them by staying home," she added.

"The Good Doctor" is working on a donation of a similar kind, an ABC spokesperson said.

"The Resident" on FOX also made a generous donation of medical supplies. Dr. Karen L. Law, the program director of the Internal Medicine Residency Program at Emory University in Atlanta, took a photo of the items outside the hospital and thanked the show.

View this post on Instagram

"Look for the helpers. You will always find people who are helping." . To the entire team @theresidentonfox, thank you for this incredibly generous donation of #PPE from your set, including gowns, masks, gloves, and all the things our healthcare workers need to provide safe care for our community during #COVID19. . Yesterday, I had a serious discussion with the residents about how, though supplies are low, a magical shipment of masks is unlikely to arrive. And yet, a magical shipment of masks DID arrive, in the form of this very generous gesture. This kind of community support means so much to our #frontlineproviders who are making many sacrifices to staff our hospitals and care for our community. . Thank you, @theresidentonfox and @foxtv for being helpers. We needed this kind of good news today. . PS: Sorry it's not a great pic, but the focus was not on the photo at the time. Similarly, the team @theresidentonfox are good citizens doing good deeds and not looking for a shout out. Though I encourage all to support The Resident and the great team behind the show and to pay their good deed forward any way you can. . #Hurstlife #residentlife #emoryIMresidents #lookforthehelpers #gratitude

A post shared by klaw (@karen.ll.law) on Mar 18, 2020 at 12:27pm PDT

"Yesterday, I had a serious discussion with the residents about how, though supplies are low, a magical shipment of masks is unlikely to arrive," she wrote. "And yet, a magical shipment of masks DID arrive, in the form of this very generous gesture. This kind of community support means so much to our#frontlineproviderswho are making many sacrifices to staff our hospitals and care for our community."

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"Grey's Anatomy" and other shows are donating necessary medical supplies during coronavirus crisis - CBS News

The TVLine-Up: What’s Returning, New and Leaving the Week of Jan. 19 – TVLine

RELATED STORIES

This weekly feature is in addition to TVLines daily What to Watch listings.

With more than 530 scripted shows now airing across broadcast, cable and streaming, its easy to forget that a favorite comedy is returning, or that the new prestige drama you anticipated is about to debut. So consider this our reminder to set your DVR, order a Season Pass, pop a fresh Memorex into the VCR however it is you roll.

This week, youll find 11 series return from winter break (including Greys Anatomy, Riverdale and The Conners), 11 season premieres (including Curb Your Enthusiasm, Project Blue Book and Station 19), 11 debuts (including 9-1-1: Lone Star, Outmatched and Star Trek: Picard) and so much more.

Sunday, January 193:05 pm AFC Championship Game (CBS)6 pm NFC Championship Game (Fox)8 pm Batwoman returns (The CW)8 pm Kids Say the Darndest Things Season 1 finale (ABC)8 pm Ray Donovan Season 7 finale (Showtime)8 pm SAG Awards (TNT, TBS)9 pm Supergirl returns (The CW)10 pm 9-1-1: Lone Star series premiere (Fox; special night and time)10 pm Avenue 5 series premiere (HBO)10 pm Vienna Blood series premiere (PBS)10:30 pm Curb Your Enthusiasm Season 10 premiere (HBO)

Monday, January 203 am Family Reunion Part 2 premiere (Netflix)3 am Love Island UK Season 6 premiere (Hulu)8 pm 9-1-1: Lone Star regular time slot premiere (Fox)8 pm All American returns (The CW)8 pm Brain Games Season 8 premiere (NatGeo)9 pm Black Lightning returns (The CW)9 pm Prodigal Son returns (Fox)10 pm Carter Season 2 premiere (WGN America)10 pm Spy Games series premiere (Bravo)

Tuesday, January 213 am Jim Hensons Word Party Season 4 premiere (Netflix; all episodes)3 am Fortune Feimster: Sweet & Salty comedy special premiere (Netflix)8 pm Arrows planted spinoff pilot episode (The CW; special time)8 pm The Conners returns (ABC)8:30 pm Bless This Mess returns (ABC)9 pm Legends of Tomorrow Season 5 premiere (The CW)10 pm Project Blue Book Season 2 premiere (History)10 pm Running Wild With Bear Grylls Season 5 finale (NatGeo)

Wednesday, January 223 am Pandemic: How to Prevent an Outbreak docuseries premiere (Netflix; all episodes)8 pm Riverdale returns (The CW)10:30 pm Awkwafina Is Nora From Queens series premiere (Comedy Central)

Thursday, January 233 am Ghost Bride series premiere (Netflix; all episodes)3 am October Faction series premiere (Netflix; all episodes)8 pm Station 19 Season 3 premiere (ABC; new time slot)8:30 pm Outmatched series premiere (Fox)8:30 pm Star Trek: Picard series premiere (CBS All Access)9 pm Greys Anatomy returns (ABC; new time slot)9:30 pm Perfect Harmony Season 1 finale (NBC)10 pm A Million Little Things returns (ABC; new time slot)10 pm The Gayle King Grammy Special (CBS)

Friday, January 243 am Chilling Adventures of Sabrina Part 3 premiere (Netflix; all episodes)3 am Encore! Season 1 finale (Disney+)3 am The Goop Lab With Gwyneth Paltrow series premiere (Netflix; all episodes)3 am Pick of the Litter Season 1 finale (Disney+)3 am The Ranch Part 8 premiere (Netflix; all episodes)3 am Shrill Season 2 premiere (Hulu; all episodes)3 am The World According to Jeff Goldblum Season 1 finale (Disney+)8 pm U.S. Figure Skating Championship (NBC)9 pm MTV Presents: A 2020 Grammy Celebration special (MTV)

Saturday, January 258 pm Flirty Dancing Season 1 finale (Fox; two episodes)8 pm NHL All-Star Game (NBC)11:30 pm Saturday Night Live returns with host Adam Driver (NBC)

For the latest renewal/cancellation status on your favorite shows, visit our Cable, Streaming and Broadcast-TV renewal scorecards.

Whats on your TVLine-Up for the week ahead?

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BWW Review: Alice Birch’s ANATOMY OF A SUICIDE, A Verbal Chamber Trio Themed On A Neurological Legacy – Broadway World

"The text has been 'scored'," states the script for British playwright Alice Birch's Susan Smith Blackburn Prize-winning Anatomy of a Suicide, a fascinating, tragic piece about a neurological legacy shared by three generations of women, now receiving a fine American premiere at the Atlantic's Linda Gross Theater.

Mapped out like a chamber trio, each page of text contains up to three columns of dialogue, representing up to three scenes that play simultaneously, with lines, beats and hesitations precisely marked so that that author dictates exactly what is heard when.

Sometimes scenes mesh and cohabitate generously. Sometimes they collide, and when they do, those foolish enough to try and follow it all at the same time will surely suffer a metal jam-up, but through tone and staging, director Lileana Blain-Cruz effectively guides our attention, though naturally, audience members may tend to focus on the scenes played closest to them.

The triptych is played out on designer Mariana Sanchez's neutrally institutional set, with the most prominent, and given the title of the play, the most ominous visual being the upstage clawfoot bathtub.

It begins in a hospital corridor where Carol's (Carla Gugino) bandaged wrists provide all the exposition needed. Her husband's (Richard Topol) attempts at support are perceived by her as an annoyance and the birth of their daughter Anna seems an unwanted anchor, adding a guilty consequence to Carol's giving in to the desire her disease fuels.

Precocious young Anna is played by Ava Briglia, and her presence informs our view of the character as an adult (Celeste Arias), who endures drug addiction and has a child with her filmmaker husband Jamie (Julian Elijah Martinez).

That child, Bonnie (Gabby Beans), grows up to be a doctor, whose protective emotional shall tests the open-hearted romantic persistence of the smitten patient (Jo Mei) she hesitantly starts dating.

If the characters aren't written with substantial depth, that's not a flaw. The focus is on finding clues within the simultaneously played stories that draw parallels, and suggest inherited characteristics, among the three main women.

Supporting actors play multiple parts and keeping track of who's who can get confusing (Whose little kid is Briglia in this scene?), but ANATOMY OF A SUICIDE is worth the extra concentration.

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BWW Review: Alice Birch's ANATOMY OF A SUICIDE, A Verbal Chamber Trio Themed On A Neurological Legacy - Broadway World

Beanie Feldstein Says Her Dreams Came True After Landing Greys Anatomy Role: Its All Ive Wanted – Us Weekly

James Pickens Jr. and Beanie Feldstein on Greys Anatomy. ABC/Ali Goldstein

When the dreams that you wish come true! Beanie Feldstein opened up about an exciting moment in her career getting to appear on her favorite show, Greys Anatomy.

It was announced on Thursday, February 27, that the Booksmart actress, 26, would be stopping by Grey Sloan Memorial Hospital. In the shows latest episode, Feldstein played an intern named Tess Desmond.

MY DREAMS CAME TRUE LAST NIGHT!!!!!!!!!!!!!!!!!!!!!! All Ive wanted since I was eleven years old was to be on Greys Anatomy, the Golden Globe nominee wrote via Instagram on Friday, February 28, captioning a post filled with photos of herself on set. Ive seen every single episode multiple times. Guest-starring on this show and getting to share scenes with the remarkable James Pickens (my chief always & forever) was heaven.

Feldstein continued, The crew and cast were so incredibly kind and let me tour all the sets and touch all the props and I fully wept!!!! Thanks for letting me take a one time dream trip to Seattle.

Feldsteins accomplishment was met with the highest of praises from major stars. Dakota Fanning simply wrote, Dr. Desmond!!!!! beneath the post, while Reese Witherspoon replied, Paging Dr. Feldstein! Aly Michalka added, Wholesome content I needed.

Not long before Feldsteins appearance on the popular medical drama, the Lady Bird actress guest-voiced a character on another iconic series: The Simpsons.

Getting to bring my nephews to watch me record The Simpsons was the greatest day. the coolest ever, she said via Instagram of the experience on Tuesday, February 25. Thanks to everyone at The Simpsons for making me seem like a cool aunt for one single day!!

Feldstein joined Greys Anatomy one month after Justin Chambers exit from the ABC series after 16 seasons. He confirmed his departure in a statement to Deadline on January 10.

Theres no good time to say goodbye to a show and character thats defined so much of my life for the past 15 years, the 49-year-old actor, who played Alex Karev, said. For some time now, however, I have hoped to diversify my acting roles and career choices. And, as I turn 50 and am blessed with my remarkable, supportive wife and five wonderful children, now is that time.

A sendoff for Chambers character, Alex, will air on Thursday, March 5, in an episode titled, Leave a Light On.

Greys Anatomy airs on ABC Thursdays at 9 p.m. ET.

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Beanie Feldstein Says Her Dreams Came True After Landing Greys Anatomy Role: Its All Ive Wanted - Us Weekly

Monday on TV: ‘Grey’s Anatomy’ producer tries to improve on … – Salt Lake Tribune (blog)

It's lavish, multi-racial and a bit of a confusing mess.

And, apparently, being Shonda Rhimes will only get you so far. ABC ordered only seven episodes of "Still Star-Crossed," and it's airing them during the summer, with a debut on Memorial Day.

Elsewhere on TV

Stanley Cup Final (6 p.m., NBC/Ch. 5): Game 1 Nashville Predators at Pittsburgh Penguins

"Michael Jackson: Searching for Neverland" (6 p.m., Lifetime): Jackson life is recalled by his bodyguards. Really.

"Gotham" (7 p.m., Fox/Ch. 13): Gordon races to save the city from the Alice Tetch virus; some of Gotham's worst villains band together.

"The Bachelorette" (8 p.m., ABC/Ch. 4): Ashton Kutcher and Mila Kunis judge a contest; Kareem Abdul Jabbar plays basketball with the guys; one bachelor betrays Rachel.

"Lucifer" (8 p.m., Fox/Ch. 13): In the Season 2 finale, Charlotte accidentally burns a man to death and Lucifer has to keep Chloe from figuring out what happened.

"American Dad" (8 p.m. TBS): The town turns on Steve after he convinces the star quarterback of the arena-football team to quit playing.

"Angie Tribeca" (8:30 p.m., TBS): Holy 'Blindspot'! A naked woman emerges from a child's backpack and doesn't remember a thing.

National Memorial Day Concert (10 p.m, Ch. 11): Recorded on Sunday.

"Leah Remini: Scientology & the Aftermath" (10 p.m., A&E): In this two-hour special, Leah Remini and Mike Rinder explore the relationship between the Church of Scientology and its critics.

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Monday on TV: 'Grey's Anatomy' producer tries to improve on ... - Salt Lake Tribune (blog)

Greys Anatomy Fans Are Really Worried Miranda Bailey Might Die in Tomorrows Episode – Cosmopolitan

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Greys Anatomy fans are pretty used to death at this point. Like, basically every favorite and beloved character on this show has been written off in the 16 seasons its been on, except for a handful of OGs. But fans are worried about Miranda Bailey in tomorrow nights mid-season finale. Yes, really.

One fan on Reddit pointed out that the show has been treating her character in a really similar way to how they treated Derek before he died.

Umm...WHOA. I mean, this person makes some valid points, but that would be crazy, right? Some fans who replied to this Reddit comment disagreed with the original poster, but others thought the analysis was spot on.

Bailey has been pissing a lot of people off this season with her lack of support for Meredith during her insurance fraud scandal. Earlier this year, fans pointed out that Bailey herself had also committed insurance fraud back in the day, which made her firing Meredith feel even more annoying. The hypocrisy!

But at the same time, the show did just reveal that shes pregnant with her second child, so it would be pretty weird for them to kill her off now. Thatd be brutal, even for Greys. Guess well have to tune in tomorrow night to see!

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Greys Anatomy Fans Are Really Worried Miranda Bailey Might Die in Tomorrows Episode - Cosmopolitan

Grey’s Anatomy recap: ‘Leave It Inside’ – EW.com (blog)


EW.com (blog)
Grey's Anatomy recap: 'Leave It Inside'
EW.com (blog)
Meredith has actually removed the giant tumor from the wall of her bedroom and left it outside Amelia's room. It's a new era in Grey's Anatomy, but to be fair, when you're courting a new man, I think we've all had that moment when we've said, It's ...
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Grey's Anatomy recap: 'Leave It Inside' - EW.com (blog)

Riverdale Season 1, Episode 12 Recap: "Anatomy Of A Murder" – Refinery29

Dramatic revelations in penultimate episodes often prove to be pivotal in the life of a new series beyond mere plot mechanics. Its at this point that a show either proves to be worthy of admiration or falls apart under the weight of its own ambition. Riverdale has been one of the most engaging, blissfully bonkers, and visually rich new shows Ive seen in a long time. It knows exactly how to hit that elusive sweet spot that so many teen dramas aim for. But I was worried that the reveal of Jasons murderer wouldnt meet my expectations. Part of my apprehension stems from the nagging issues that have been weighing down recent episodes like Veronicas off-putting characterization and the complete sidelining of characters I previously enjoyed like Josie. But Anatomy of a Murder didnt just meet my expectations it exceeded them. Im left yearning for more high-intensity drama, witty comebacks, and family drama. This episode has everything. Incest, maple syrup intrigue, unhinged mothers, several showdowns, and Alice holding a gun, proving once again shes not one to be messed with. This isnt the kind of exhilarating and fun episode that quickly fades from memory. By exploring the fractures within these families its able to be emotionally impactful too.

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Riverdale Season 1, Episode 12 Recap: "Anatomy Of A Murder" - Refinery29

New book ‘Anatomy of Innocence’ allows wrongfully convicted to tell their stories – 89.3 KPCC

People who have made good faith estimates are hoping that our human system of criminal justice gets it right 95% of the time. If we got it right 95% of the time there would still be 110,000 innocent people in jail. -- Laura Caldwell, co-editor, "Anatomy of Innocence"

In recent years, wrongful conviction stories like the ones in Serial and Netflixs Making a Murderer have captivated audiences. The characters in these stories are ordinary people. That's what makes the stories so intriguing this could happen to anyone.

Anatomy of Innocence is a new anthology that tells the stories of over a dozen people who were convicted of crimes they did not commit. What makes it unique is that the stories are told by the actual exonerees, with the help of thriller and mystery writers like Sara Paretsky, Lee Child, Brad Parks, and Laurie King. Laura Caldwell and Leslie Klinger teamed up to co-edit the collection of stories.

Author Laura Caldwell is a professor at Loyola University Chicago School of Law. In 2008, she founded Life After Innocence at Loyola, which provides resources for innocent people who have been affected by the criminal justice system as they re-enter society. Leslie Klinger is best known for his annotated editions of Sherlock Holmes, Dracula, and the works of H.P. Lovecraft.

Off-Ramp archive: Leslie Klinger on H.P. Lovecraft ... great writer, horrible man

They worked together on Anatomy of Innocence to examine the real life consequences of wrongful convictions. The idea was to present them almost like a novel to present the arc, to present the typical experience of the exonerees, Klinger says. From the very first moment from the arrest all the way through reentering society and the mental adjustments.

Sales of the book support Life After Innocence, and if it sells well enough, some of the proceeds will go to the exonerees who tell their stories. The book sites statistics from the National Registry of Exonerations, a registry kept by Northwestern University Pritzker School of Law, which says there are about 2,000 cases of exonerations that have been publicly recognized.

Klinger says they worked hard to mirror the overall demographics of the wrongfully convicted: almost a third are black, about 10% were first arrested under the age of 18, and half were under the age of 25 when they first became involved in their case and ended up incarcerated.

Its not always about being at the wrong place at the wrong time.

67% of wrongful convictions that involved big level felonies involved prosecutorial or police misconduct, Caldwell says. Now, that is not to say that the majority of police or prosecutors engage in misconduct unfortunately we have seen such egregious things happen on behalf of police and prosecutors.

When we were envisioning this book Making a Murderer wasnt out, but Serial was. The average person wasnt as well versed in wrongful convictions, Caldwell says. By the time we got to actually publishing, the hope is that you understand that this happens. Its a human system it's bound to happen for various reasons so now that its bound to happen for various reasons what does it feel like to be in that person's head? What does it feel like to be in their soul? What does it feel like to be in their eyes?

For the full conversation with Laura Caldwell and Leslie Klingerclick on the audio player above.

With contributions from Jesus Ambrosio

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New book 'Anatomy of Innocence' allows wrongfully convicted to tell their stories - 89.3 KPCC

‘Grey’s Anatomy’ Fans Lose It Over Idea of Mr. Schue as Jo’s Abusive Husband – Moviefone

Will Shuester may need detention for his upcoming behavior on "Grey's Anatomy." A few days ago, the news came out that "Glee" alum Mattthew Morrison would be joining "Grey's" Season 13 as Dr. Paul Stadler. Photos showed him with Justin Chambers (Alex Karev) in Episode 23.

All of that pointed directly to Morrison booking the role of Dr. Jo Wilson's (Camilla Luddington) abusive husband, from whom she fled. It was previously reported that "Grey's" was casting a new doc for the final four episodes of this season, with a possible return in Season 14. TVLine said they were seeking "a Caucasian actor in his mid 40s to play a new doctor who is 'appealing, charismatic and charming' in other words, a total freakin' catch. The twist? He's has a 'manipulative, scary dark side.'"

That was always expected to be Jo's hubby. We don't even know Jo's real name, but it's possible her last name is still Stadler, if Morrison's character is indeed her husband. It also fits to have Alex in the picture, since it would be a very Alex thing to do to track him down to get a divorce in motion -- or just to confront the guy for what he did -- so Jolex can get married and begin their lives together.

Fans reacted to the news of the beloved "Glee" alum playing an abuser; one viewer summed up the general response with "IM F*CKING SCREAMING JO'S HUSBAND IS WILL SCHUESTER." Here are more reactions:

"Grey's Anatomy" is airing Season 13, Episode 18 tonight (Thursday, March 30). There are 24 episodes to this season, so we won't meet Morrison's new doctor for a while.

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'Grey's Anatomy' Fans Lose It Over Idea of Mr. Schue as Jo's Abusive Husband - Moviefone