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Cavaliers have no chemistry: Comment of the Day

Posted on March 29, 2012 by Danzig

The Cavaliers' losing streak reached five games last night following a 87-75 loss to the Detroit Pistons at The Q. The Cavs have lost 8 of 9, with 6 of those losses by at least 10 points.

In today's Comment of the Day, Slimshady blames the struggles on the trade of Ramon Sessions and the release of Ryan Hollins,

"The Cavs chemistry they had before with Sessions & Hollins being dumped and the injury to Boobie is gone. The trade of Ramon Sessions has killed the Cavs. He was the second best guard on the team. Sloan & Harris are just bodies that breath that's all. The team is gutted with the trade of Ramon and the dumping of Hollins. What the Cavs team lacked in talent they made up with in chemistry, energy & coaching. The Cavs used to be fun to watch this season but now they are horrible after they were gutted."

Are the Cavaliers unwatchable? With four picks in the upcoming draft, are you OK with that? Get in on the discussion below.

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Cavaliers have no chemistry: Comment of the Day

State opens up nominations for green chemistry awards

Posted on March 26, 2012 by Danzig

LANSING, MI (WNEM) -

Going Green could earn you an award from the state. The Michigan Department of Environmental Quality (EPA) has announced open nominations for the fourth annual Michigan Green Chemistry Governor's Awards.

The Governor's Awards recognize advances that incorporate the principles of green chemistry into chemical design, manufacture, or use, or that promote activities which support or implement those technologies and efforts. The awards acknowledge efforts to design and implement safer and more sustainable chemicals, processes, and products.

Awards are open to individuals, groups, and organizations, both non-profit and for profit. The program was established by the Michigan Green Chemistry Roundtable, and it celebrates innovations using green chemistry in Michigan. Eleven awards have been presented in the first three years of the program.

Entries must be sent no later than July 20. The awards will be presented at the 2012 Michigan Green Chemistry and Engineering Conference: "Driving Sustainable Manufacturing," which is scheduled Oct. 26 at Wayne State University.

For a copy of the nomination packet, or more information on the Michigan Green Chemistry Program, visit the DEQ Web site at http://www.michigan.gov/greenchemistry, or call the DEQ Environmental Assistance Center at 800662-9278.

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State opens up nominations for green chemistry awards

Chemistry in one dimension offers surprising result

Posted on March 27, 2012 by Danzig

"Chemistry on the nanometer scale often appears to be different compared to chemistry in the normal scale and carbon nanotubes provide ideal conditions for studies of reactions in nanospace," says Alexandr Talyzin, docent at the Department of Physics, Ume University.

The standard approch to make chemical recations inside of single walled carbon nanotubes, SWNTs, is to fill the inner space with molecules (e.g. fullerenes, thus forming so called peapods) and make them react with each other.

The nanotube walls will then protect the encapsulated molecules from outer space and make reactions with molecules and atoms outside the tube impossible. Once the SWNTs are filled with C60 molecules there is not enough space for hydrogen molecules to go in. That was the common opinion when the research groups started their experiments a few years ago.

But their experiments leave no doubt, hydrogen does actually penetrate into peapods and react with fullerenes. The evidence is rather direct, when the temperature and pressure of hydrogenation is taken to extreme values the fullerene cage collapses completely and large hydrogen molecules are formed. This was confirmed both by Raman spectroscopy and high resolution TEM.

The study provides one more example that chemical reactions in nanoreactors are not always the same as in normal conditions. In three-dimensional structure molecules can react with their neighbours in all possible directions, up, down, right, left etc.

"Inside of carbon nanotubes fullerene molecule have only two neighbours, lets say to the right and to the left. Similarly, the reaction with hydrogen is also limited to one-dimension," says Alexandr Talyzin.

A great advantage is that even single molecules inside of SWNTs can be observed using high resolution electron microscopy, something extremely difficult for bulk powders, he adds. High quality images collected at Aalto University allowed the scientists to observe not only hydrogen induced collapse of C60, but also hydrogen-driven coalescence of molecules into chain polymers and tubules.

"What we learned is a rather general result for nano-chemistry. Now we have direct evidence that molecules inside of SWNts can be reacted with gases. It opens enormous possibilities for synthesis of novel hybrid materials and chemical modification of encapsulated molecules and materials," says Alexandr Talyzin.

More information: Hydrogen driven collapse of C60 inside of SWNTs is published on line in Angewandte Chemie, http://onlinelibra 946/abstract

Provided by Umea University

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Chemistry in one dimension offers surprising result

Wiley-VCH and ACES to launch organic chemistry journal rooted in Asia

Posted on March 27, 2012 by Danzig

Public release date: 26-Mar-2012 [ | E-mail | Share ]

Contact: Jennifer Beal physicalsciencenews@wiley.com 44-012-437-70633 Wiley-Blackwell

Weinheim, Germany -- Wiley-VCH, part of the scientific and technical publishing business of John Wiley & Sons, Inc., and the Asian Chemical Editorial Society (ACES) today announced the launch of the Asian Journal of Organic Chemistry, the second pan-Asia society chemistry journal after Chemistry An Asian Journal (2010 Impact Factor: 4.188), launched by ACES and Wiley-VCH in 2006.

ACES is an association of 13 chemical societies in Asia and the Pacific region (the Royal Australian Chemical Institute Inc., the Chinese Chemical Society, the Hong Kong Chemical Society, the Chemical Research Society of India, Himpunan Kimia Indonesia, the Chemical Society of Japan, the Korean Chemical Society, Institut Kimia Malaysia, the New Zealand Institute of Chemistry, the Singapore National Institute of Chemistry, the Chemical Society Located in Taipei, the Chemical Society of Thailand, and the Chemical Society of Vietnam). For the publication of the Asian Journal of Organic Chemistry, ACES is joined by the Korean Society of Organic Synthesis.

The Asian Journal of Organic Chemistry (www.AsianJOC.org) will publish strictly peer-reviewed primary and secondary research in all aspects of organic chemistry. The first issue will appear in print and online in Wiley Online Library in the autumn of 2012 and will be published monthly thereafter. The Asian Journal of Organic Chemistry is a sister journal of the European Journal of Organic Chemistry, which is published by Wiley-VCH and ChemPubSoc Europe, the sister organization of ACES in Europe.

The Editorial Board is co-chaired by Sung Ho Kang from the Korea Advanced Institute of Science and Technology (Daejeon), Keiji Maruoka from Kyoto University, and Deqing Zhang from the Institute of Chemistry, Chinese Academy of Sciences (Beijing), whose combined and extensive expertise in organic chemistry reflects the broad scope of the Asian Journal of Organic Chemistry. In a joint statement, the Co-Chairs said, "Until now, the top international organic chemistry journals have been either American or European; the Asian Journal of Organic Chemistry is the realization of a dream for organic chemists in Asia".

Among others, Nobel Laureates Ei-ichi Negishi (2010), Akira Suzuki (2010), and Ryoji Noyori (2001) support the new journal as members of the Honorary Board. Kang, Maruoka, and Zhang are joined by a host of distinguished organic chemists on the Editorial and International Advisory Boards to ensure that the Asian Journal of Organic Chemistry is of the highest possible standard.

"The launch of the Asian Journal of Organic Chemistry reflects the extraordinary and continuing growth of the organic chemistry community in Asia" said the President of ACES, Youngkyu Do (Korea Advanced Institute of Science and Technology). "The opportunity to bring this to the global stage in a focused, high-quality publication is exciting" he added. Koji Nakanishi, a prominent member of the organic chemistry community and member of the journal's Honorary Board, remarked that: "In view of the surge in contributions from Asian countries, the launch [of the Asian Journal of Organic Chemistry] is wonderful".

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Gut on a chip

Posted on March 25, 2012 by Danzig

We’ve had the heart on a chip, kidney on a chip and brain on a chip. Now, we’ve got another body part on a chip – the gut.

This gut on a chip, designed by Donald Ingber from Harvard University in the US, and colleagues, is quite special as it mimics the gut’s structure, conditions and even the peristaltic motions (gut muscles contracting and relaxing in turn along the tube to move food along). The team hopes that it’ll replace animal guts used in studies, such as seeing how drugs are absorbed into the body through the gut.

The team made the device from two microfluidic channels separated by a porous flexible membrane coated with extracellular matrix and lined with human intestinal epithelial cells. To recreate the natural gut’s environment, they had fluid flowing through the tube at a low rate and they exerted a strain on the tube at constant intervals to mimic peristalsis.

— A schematic of the gut-on-a-chip showing the flexible porous extracellular matrix-coated membrane lined by gut epithelial cells crossing horizontally through the middle of the central microchannel, with vacuum chambers on both sides. The mechanical strain is exerted by applying suction to the vacuum chambers

Under these conditions, a columnar epithelium developed, which grew into folds – similar to the structure of intestinal villi. Then, the team grew a normal intestinal microbe (Lactobacillus rhamnosus) on the epithelium’s surface, which survived for around a week (not an easy thing to achieve, they say).

Together, these components make a more realistic model than current systems that could be used for absorption and toxicity studies, transport, drug tests and to develop new intestinal disease models.

If you want to find out more about body parts on chips and their uses, the journal Lab on a Chip has loads of papers on the topic.

Elinor Richards

Source:
http://prospect.rsc.org/blogs/cw/?feed=rss2

PerkinElmer Launches Ensemble for Chemistry Informatics Platform at ACS 2012

Posted on March 26, 2012 by Danzig

SAN DIEGO--(BUSINESS WIRE)--

At the American Chemical Societys Spring 2012 National Meeting & Expo, PerkinElmer, Inc., a global leader focused on improving the health and safety of people and the environment, today announced the launch of its Ensemble for ChemistryTM integrated informatics suite for enhancing chemist productivity and decision-making, for industry segments including biopharmaceutical, environmental, food and chemical, as well as academia and government.

The Ensemble for Chemistry platform provides a suite of software applications to improve chemists efficiency. This is delivered through tools and content for more efficient planning and recording of experiments, the creation of structure-searchable databases of compounds, reactions and data, and the ability to locate, share and communicate results directly in their workflow.

The software suite allows users to manage chemical structures and their associated data and properties in intelligent and intuitive ways, and integrates disparate data from customers' Electronic Laboratory Notebooks (ELN), informatics systems and databases, maximizing the value of an organization's scientific intellectual capital.

Chemists across a wide range of scientific and commercial endeavors, whether from academic, biopharma, environmental, food or other segments, share the same core informatics needs ease of use, workflow efficiency, data integrity, knowledge sharing and collaboration, and secure storage, said Michael Stapleton, general manager, Informatics, PerkinElmer. The Ensemble for Chemistry suite provides researchers with the tools they need to understand the chemistry behind the names, structures and reactions, so that compounds and associated data are leveraged effectively on business-relevant pipeline projects.

The Ensemble for Chemistry suite helps businesses meet the challenges facing chemists by enabling them to:

About PerkinElmer, Inc.

PerkinElmer, Inc. is a global leader focused on improving the health and safety of people and the environment. The Company reported revenue of approximately $1.9 billion in 2011, has about 7,000 employees serving customers in more than 150 countries, and is a component of the S&P 500 Index. Additional information is available through 1-877-PKI-NYSE, or at http://www.perkinelmer.com.

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PerkinElmer Launches Ensemble for Chemistry Informatics Platform at ACS 2012

American Chemical Society Presidential Sessions focus on outreach, chemistry innovations

Posted on March 24, 2012 by Danzig

Public release date: 24-Mar-2012 [ | E-mail | Share ]

Contact: Michael Bernstein m_bernstein@acs.org 619-525-6268 (March 23-28, San Diego Press Center) 202-872-6042

Michael Woods m_woods@acs.org 619-525-6268 (March 23-28, San Diego Press Center) 202-872-6293 American Chemical Society

SAN DIEGO, March 23, 2012 More than a dozen symposia and other events at the American Chemical Society (ACS) 243rd National Meeting & Exposition are being sponsored or recommended by noted science communicator and ACS President Bassam Z. Shakhashiri, Ph.D. They range from a science outreach event for children at PETCO Park to news from an emerging field of chemistry that promises to produce medicines inside patients' bodies, as well as a symposium on communicating science to the public.

Communicating science is a major part of Shakhashiri's presidential theme for the year. The William T. Evjue Distinguished Chair for the Wisconsin Idea at the University of Wisconsin-Madison, Shakhashiri is noted internationally for pioneering the use of demonstrations in the teaching of chemistry in classrooms, as well as to the public in museums, convention centers, shopping malls and retirement homes and at his Science is Fun website. The Encyclopedia Britannica termed Shakhashiri the "dean of lecture demonstrators in America."

Shakhashiri said the symposia connect with the grand challenges that face society and scientists in the 21st century, challenges that range from helping to sustain Earth and its people in the face of population growth and climate change to finite resources, malnutrition and spreading disease.

A schedule of the sessions appears at the end of this press release, and individual topics can be accessed online.

Among the speakers in the plenary session, which is among Shakhashiri's recommendations:

Carolyn Bertozzi will deliver the Kavli Foundation Innovations in Chemistry Lecture. She is the T.Z. and Irmgard Chu Distinguished Professor of Chemistry and Professor of Molecular and Cell Biology at UC Berkeley, an Investigator of the Howard Hughes Medical Institute and Senior Faculty Scientist at the Lawrence Berkeley National Laboratory. Her interests span the disciplines of chemistry and biology with an emphasis on studies of sugars that coat the surfaces of cells. Her innovations could someday lead to new ways of making medicines inside the human body.

Another highlight of the ACS 243rd National Meeting & Exposition is a session called, "Communicating Chemistry to the Public." A featured speaker is Paul Raeburn, winner of the ACS 2012 James T. Grady-James H. Stack Award for Interpreting Chemistry for the Public. Raeburn is a distinguished science writer, author, editor and program director of New Horizons in Science. Other speakers include ACS President Shakhashiri and the following:

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American Chemical Society Presidential Sessions focus on outreach, chemistry innovations

A half century for the noble gases

Posted on March 25, 2012 by Danzig

This year marks a very special anniversary for the noble gases – it’s 50 years since the synthesis of xenon hexafluoroplatinate (Xe⁺[PtF₆]^–). What’s so special about that? Well, before xenon hexafluoroplatinate everyone thought the noble gases (helium, neon, argon, krypton, xenon, radon) were completely inert.

It’s one of the earliest things you’re taught in school chemistry lessons. The noble gases don’t react because their highest energy ‘shell’ of electrons is full – they don’t need to share electrons to feel complete. Thus they reside lonely and aloof in their own little world at the far end of the periodic table.

But in 1962 UK chemist Neil Bartlett coaxed them out to play with the other elements while while working with fluorine. The key was platinum hexafluoride (PtF₆), an incredibly powerful oxidising agent that Bartlett and his colleagues had shown would react with oxygen gas. The first ionisation potential of xenon is almost the same as that of oxygen, thought Bartlett. So why not give it a shot?

An explosion of interest followed, and 50 years later we’re still making new noble gas compounds. And to celebrate, the University of British Columbia in Canada, the institution at which Bartlett made his breakthrough, is hosting a special seminar on 23 March. Guest speakers include Derek Lohmann, who worked with Bartlett on the synthesis and use of platinum hexafluoride. He told me that at the time the team wasn’t wholly aware of what an important milestone it was working towards: ‘The initial feeling was one of disbelief and then euphoria.’ It took a very powerful reagent, he explained. ’Like fluorine itself and many other compounds of fluorine, platinum hexafluoride is a very reactive species owing to its ability to attract electrons.’

Andrew Turley

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Chemistry in its element – vitamin C

Posted on March 25, 2012 by Danzig

Scurvy sea dogs are a lot less scurvy thanks to this week’s compound, and Linus Pauling was convinced it could do much more. Simon Cotton puts the ‘c’ in citrus with vitamin C in this week’s Chemistry in its element podcast.

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Chemistry professor to speak on ionic liquids

Posted on March 23, 2012 by Danzig

Dr. Keven Miller, Assistant Professor of Chemistry at Murray State University, addressed a talk on Adventures in Ionic Liquids: From Reactions to Solvents to Macromolecular Architectures to students, faculty, and members of the UT Martins Student Members of the American Chemical Society (SMACS) last Thursday.

Dr. Miller says, Ionic liquids are salts that exist in the liquids state. Typical salts (like sodium chloride - table salt) are highly crystalline and require extremely high temperatures to melt. Ionic liquids are poorly coordinated and the melting point is below 100 degrees Celcius, so they are not fully crystalline. Although ionic liquids have been around for nearly a century, the term ionic liquid has been accepted only within the last 15-20 years. Ionic liquids are used in a number of industrial processes such as acid scavenging and cellulose processing. More recently (last 10-15 years) ILs (ionic liquids) have been used more as greener replacements for volatile organic solvents in common organic reactions. Ionic liquids have negligible volatility, flammability and a lower toxicity profile. Some ionic liquids have even been shown to be biodegradable.

Dr. Miller goes on to name the four main classes of ionic liquids cations. They include ammonium, imidazolium, pyridinium, and phosphinium. Anions are not mentioned because they can vary widely.

Dr. Miller then explained the Michael Addition. The Michael Addition is a versatile, efficient method of forming new carbon-carbon bonds. According to Dr. Miller, base catalysts such as carbonate and bicarbonate can range from weak, to moderate, the amine group, to strong, the amides and hydrides groups.

The reactions are done in volatile toxic solvents. Dr. Millers interest on this topic of Michael Addition is how fast the reactions work and if a reaction will even occur. In model ionic liquids, changing the cation will effect the cation-anion interactions because the larger bulky anions tend to result weaker cation-anion interactions but improved organic solubility.

Dr. Miller tested the Michael Addition and found out it was successful. The reactions occurred faster than expected.

The reason for this enhanced rate is unclear but could be due to a number of different factors, says Dr. Miller.

Michael Additions proceeds well in ionic liquid solvents. Future studies for Dr. Miller in response to the Michael Addition is to pursue other anions with phosphonium cations.

Research interests include the applications of ionic liquids in organic and polymer/materials chemistry.

Senior Engineering major Jareth Embrey had this to say about Dr. Millers talk: Most people think research presentations are about a finished product, but this was really insightful for a work still in progress.

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Chemistry professor to speak on ionic liquids

Tweaking Samples for High-Speed Chemistry

Posted on March 23, 2012 by Danzig

Tweaking Samples for High-Speed Chemistry

A nanoprinting technique can be used to modify millions of samples.

A new way to print, and modify, nanoscale molecular samples could mean faster drug discovery and scientific experimentation. Combinatorial chemistryexposing a huge array of slightly different molecules to samples in parallelis an extremely fast way to screen drug molecules, or to test the way certain molecules affect biological cells.

Researchers at the International Institute for Nanotechnology at Northwestern University, in Chicago, led by director Chad Mirkin, have devised a way to rapidly prepare the smallest type of combinatorial chemistry array. They tested the approach by exposing stem cells to different-sized samples of fibronectin, a protein that plays an important role in cell adhesion, growth, and differentiation. The researchers used a nanoprinting technique previously developed by Mirkin's group, called polymer pen lithography, that delivers samples to a substrate in parallel via the tips of millions of pyramid-shaped "pens."

The innovation was to tilt the array slightly as these molecules were deposited, so that the pyramids closest to the surface make more contact and leave more material, while those farthest away leave less. Mirkin and colleagues found that, by tilting an array just 0.01 degrees, they could create 25 million fibronectin deposits of different size and structure.

When they applied stem cells to the array, they found that the size of the fibronectin molecules controlled the differentiation of these cells. "In the experiment, we only adjusted the size," says Mirkin, whose group published their results in Proceedings of the National Academy of Science earlier this month

It may eventually be possible to change other features of samples, such as composition or shape, using the same technique. These are common features explored by drug companies, Mirkin says.

"The technique they developed is extremely powerful with the generation of a large number of features in parallel," says Bing Yan, director of the High-Throughput Analytical Chemistry Facility at St Jude's Children's Research Hospital in Memphis, Tennessee, who was not involved with the research. "The number alone is very impressive."

Along with drug testing, Yan says the approach could be used to test the reactivity of catalysts and the properties of new materials.

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Tweaking Samples for High-Speed Chemistry

HepatoChem to Present at Early-Stage Life Sciences Technology Conference VIII

Posted on March 24, 2012 by Danzig

MAHWAH, N.J., March 23, 2012 /PRNewswire/ -- HepatoChem, Inc, a chemistry-based technology platform company with a primary focus on metabolite production from bioactive small molecules, and an investment holding of Heartland Bridge Capital, Inc. (OTCBB: HLBC.OB - News), announced that it will present at the Early-Stage Life Sciences Technology Conference VIII at the Merck Research Laboratories in Boston, MA, on April 12, 2012.

The Early-Stage Life Sciences Technology Conference will showcase 20 life sciences technologies developed at the universities, research institutions, and hospitals of Massachusetts and recently formed Massachusetts companies to an audience of angel investors, venture capitalists and corporate investors. http://www.mattcenter.org/lsconf2012/

HepatoChem recently moved to its new laboratory in Beverly, MA. This is an important step for HepatoChem, which is committed to offering unique metabolite production services. This laboratory is part of the NorthShore Biotech Innoventure.

About HepatoChem, Inc

HepatoChem is a chemistry-based technology platform company with a primary focus on metabolite production from bioactive small molecules. Founded by Marc Bazin, previously with Pfizer, Inc., and Prof. John T. Groves, the Hugh Stott Taylor Chair of Chemistry at Princeton University, HepatoChem is dedicated to developing technologies that help pharmaceutical companies improve the quality of drug development pipelines. HepatoChem offers a unique and powerful solution to resolve the traditional lack of rapid and efficient metabolite access in drug discovery. http://www.hepatochem.com

About Heartland Bridge Capital, Inc.

Heartland Bridge Capital, Inc. (OTCBB:HLBC.OB - News) is a public company that, in addition to managing its own operating entities, participates in emerging companies run by exceptionally talented entrepreneurs and operating executives who are dedicated to creating positive change in our world. HLBC functions as an owner, product developer, and investor focused primarily on providing equity, acquisition debt, or bridge financing to emerging high-growth companies and entrepreneurs in the areas of clean energy, waste management, and life sciences. http://www.heartlandbridgecapital.com.

To request an investor packet, or to receive updates on Heartland Bridge Capital register online at http://www.wallstreetnewscast.com/request/hlbc.html

Safe Harbor Notice

Certain statements contained herein are "forward-looking statements" (as defined in the Private Securities Litigation Reform Act of 1995). Heartland Bridge Capital, Inc. cautions that statements made in this news release relating to the investment in HepatoChem, and potential investment in and the business direction of the Company, constitute forward-looking statements and makes no guarantee of future performance. Forward-looking statements are based on estimates and opinions of management at the time statements are made. These statements may address issues that involve significant risks, uncertainties, estimates, and assumptions made by management. Actual results could differ materially from current projections or implied results. Heartland Bridge Capital, Inc. undertakes no obligation to revise these statements following the date of this news release.

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HepatoChem to Present at Early-Stage Life Sciences Technology Conference VIII

Europe Clinical Chemistry & Immunodiagnostics Markets Discussed in New Report Published at MarketPublishers.com

Posted on March 21, 2012 by Danzig

LONDON--(BUSINESS WIRE)--

Due to a number of factors like new and more stringent regulations; advances in diagnostic technologies, system engineering, automation, and IT; as well as intensifying competition, the clinical chemistry and immunodiagnostics markets are undergoing significant changes. Some segments, such as routine chemistry, start resembling commodity markets, where product positioning and cost per test are more critical than underlying technology. All these upcoming transformations in the marketplace are expected to provide amazing opportunities for a variety of new instruments and reagent systems, as well as auxiliary products, like specimen preparation devices, controls, calibrators.

New research report The 2012 European Clinical Chemistry and Immunodiagnostics Markets: France, Germany, Italy, Spain, UK - Emerging Opportunities and Business Expansion Strategies developed by Venture Planning Group (VPG) explores future marketing and technological trends in five major Europeancountries (France, Germany, Italy, Spain and the UK) and Japan; provides estimates of the specimen, test and sales volumes, as well as major suppliers' sales and market shares; compares features of leading analyzers; profiles top market players; and identifies specific product and marketing opportunities facing suppliers during the next five years.

Companies mentioned in the report include: Abbott Laboratories, AdnaGen, Ambrilia, AMDL, Beckman Coulter, Biomedical Diagnostics, BioMerieux, Bio-Rad, Canag Diagnostics, Dako, DiaSorin, Eiken, Fujirebio, Instrumentation Laboratory, J&J, Kyowa Medex, Matritech, Roche, Siemens, Sysmex, Thermo Fisher, Trinity Biotech, Tosoh, Wako, and Wallac.

Report Details:

Title: The 2012 European Clinical Chemistry and Immunodiagnostics Markets: France, Germany, Italy, Spain, UK - Emerging Opportunities and Business Expansion Strategies Published: March, 2012 Pages: 900 Price: US$ 18,500

http://marketpublishers.com/report/medicine_pharmaceuticals_biotechnology/drugs_biotechnology/2012_european_clinical_chemistry_n_immunodiagnostics_markets_france_germany_italy_spain_uk_emerging_opportunities_n_business_expansion_strategies.html

Report Contents:

INTRODUCTION

WORLDWIDE MARKET AND TECHNOLOGY OVERVIEW A. Major Routine Chemistry Tests 1. Albumin 2. Alkaline Phosphatase 3. ALT/SGPT 4. Ammonia 5. Amylase 6. AST/SGOT 7. Bilirubin 8. Blood Gases 9. Blood Urea Nitrogen (BUN) 10. Calcium 11. Cholesterol 12. Cholinesterase 13. Creatinine 14. Electrolytes a. Carbon Dioxide/Bicarbonate b. Chloride c. Potassium d. Sodium 15. Fructosamine 16. Gamma-Glutamyl Transpeptidase (GGT) 17. Glucose 18. High Density Lipoprotein (HDL) 19. Iron 20. Lactate Dehydrogenase (LDH) 21. Magnesium 22. Phosphorus 23. Protein 24. Triglycerides

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Europe Clinical Chemistry & Immunodiagnostics Markets Discussed in New Report Published at MarketPublishers.com

Research and Markets: Metal Chemistry of Porphyrinoids

Posted on March 23, 2012 by Danzig

DUBLIN--(BUSINESS WIRE)--

Dublin - Research and Markets (http://www.researchandmarkets.com/research/67961fb7/metal_chemistry_of) has announced the addition of John Wiley and Sons Ltd's new book "Metal Chemistry of Porphyrinoids" to their offering.

The examination of porphyrins and phthalocyanines and their metal complexes remains a pillar of the chemical sciences spanning fundamental chemistry and applications to biological chemistry and design of advanced materials. While the chemistry of the metalloporphyrins and metallophthalocyanines has been extensively explored, the metal chemistry of many of the analogs and isomers of the porphyrin macrocycle has only recently matured into a significant field.

With recent significant advances in the organic chemistry of aromatic polypyrrolic macrocycles, leading to the easy availability of porphyrin analogs and isomers, research into the metal chemistry of these compounds is allowing a deeper understanding of their role in biochemistry and the development of new molecules with exciting applications in medicine, catalysis, materials science, and sensors.

Metal Chemistry of Porphyrinoids summarizes these recent synthetic developments, particularly in respect of metallation strategies for freebase porphyrinoids, as well as progress towards applications in areas such as sensor and optical materials, catalysis and medicine. This reference summarizes those developments as well as progress towards a variety of applications which mirror the many uses of normal porphyrins and phthalocyanines.

Key Topics Covered:

- Chapter 1 Introduction

- Chapter 2 Metallation strategies for the porphryinoids

- Chapter 3 Isomeric porphyrins

- Chapter 4 Ring modified porphyrins

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Research and Markets: Metal Chemistry of Porphyrinoids

Research and Markets: Supramolecular Polymer Chemistry

Posted on March 23, 2012 by Danzig

DUBLIN--(BUSINESS WIRE)--

Dublin - Research and Markets (http://www.researchandmarkets.com/research/b81e8458/supramolecular_pol) has announced the addition of John Wiley and Sons Ltd's new book "Supramolecular Polymer Chemistry" to their offering.

Presenting the work of pioneering experts in this exciting field of supramolecular polymer chemistry, this monograph covers an extensive range of applications, including drug delivery and catalysis. It focuses on new structures and phenomena of cyclodextrin-based supramolecular polymers and many other compound classes. While providing a deeper insight in macromolecular recognition and the mechanisms of living systems, this book also introduces fascinating novel phenomena beyond natural systems.

Key Topics Covered:

- Multiple Hydrogen-Bonded Supramolecular Polymers

- Cyclodextrin-Based Supramolecular Polymers

- Supra-Macromolecular Chemistry: Toward Design of New Organic Materials from Supramolecular Standpoints

- Polymerization with Ditopic Cavitand Monomers

- Polymers Containing Covalently Bonded and Supramolecularly Attached Cyclodextrins as Side Groups

- Antibody Dendrimers and DNA Catenanes

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Research and Markets: Supramolecular Polymer Chemistry

Old storyline, new chemistry and comedy in 'Bent'

Posted on March 21, 2012 by Danzig

LOS ANGELES -- It's a tale as old as time: A tough, type A lawyer hires a surfer-dude contractor to remodel her kitchen. OK, the type A lawyer and surfer-dude characters aren't that classic, but the story of two very different people finding a connection has been around forever.

NBC is banking that a new spin on this old plot will create enough sparks to make the new comedy "Bent" a hit. It will be up to Amanda Peet, the lawyer, and David Walton, the surfer, to generate those sparks.

"I think chemistry, in real life, it's hard to put words around it. You either have it with someone or you don't," Walton says. He thinks viewers will see -- and be attracted to -- the chemistry between he and Peet.

Both actors credit executive producer Tad Quill with writing a script that has enough sexual tension and sexual suspense to make it easy to create the needed sexual electricity.

"It's not something that I think about or that I set out to accomplish. It's just play the scene," Peet says of the connection she has to her co-star.

She has played those kind of scenes in TV and film projects before, from "Studio 60 on the Sunset Strip" to "The Whole Nine Yards." The key to making the audience believe there is some type of connection is believable casting.

Peet and Quill knew immediately Walton was the guy for "Bent."

"When Tad and I were looking for a co-star, we definitely wanted to find something that would make the show really sexy. We wanted to create a real kind of lifestyle rift between these two people. And when David Walton came in, it was obvious that he was our guy. And, frankly, from the bottom of my heart, I am shocked that I get to be with him and not Reese Witherspoon or Jennifer Lopez or some movie star right now because he's just a really crazy genius combination of being really funny and really gorgeous and kind of a dork," Peet says. "I feel very lucky that we found him."

Walton is a veteran of situation comedies, having starred in "Perfect Couples," "100 Questions" and "Cracking Up."

Quill, who worked as a producer on "Scrubs," "Spin City," "Good Morning, Miami" and "Samantha Who?," wants "Bent" to have the same romantic comedy elements of those shows while being just a little different.

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Old storyline, new chemistry and comedy in 'Bent'

Proctor chemistry students participate in March Madness

Posted on March 21, 2012 by Danzig

Studentsin Mary Ann Mazzolas chemistry class at Proctor High School in Utica are among 10,000 high school students in the United States who are experiencing their own March Madness as they participate in local Chemistry Olympiad competitions the first step toward securing a spot on the U.S. Chemistry Olympiad team.

Later this summer, the team will go up against chemistry students from 70 other nations at the 44th International Chemistry Olympiad outside Washington, D.C.

Next month, Mazzolas top two chemistry students will go on to take the U.S. National Chemistry Olympiad national exam with the top two students from all other participating high schools in the country.

Selection for the national exam is based on scores in the local competition and teacher recommendations. The top 20 students from the national competition are then invited to a two-week intensive study camp held in June at the U.S. Air Force Academy in Colorado Springs.

At the camps conclusion, the final four students are chosen to represent the United States at the International Chemistry Olympiad, where they compete with the worlds most talented high school students for gold, silver and bronze medals.

The local examinations consist of 60 multiple-choice questions representing a fairly wide range of difficulty, usually completed in 110 minutes. The three-part, 4.5-hour national exam includes multiple-choice questions, problem solving and a lab.

Guest Post: Apple Succumbs To Battery Chemistry?

Posted on March 20, 2012 by Danzig

Submitted by Sabregold1999

Apple Succumbs To Battery Chemistry

In light of the news that Apple is issuing a dividend with the stock flirting with all-time highs, it might be a good time to assess where Apple is with its two products, the Iphone and the Ipad. There is no arguing with the success of these products, but that is not the real story that needs addressing. The real story for Apple is battery chemistry and much like the automakers it fails.

Apple, like a lot of gadget makers needs new iterations to generate a buzz. If the newest product lacks significant improvements the growth model suffers. For Apple any and all great innovations on the hardware side will be limited, simply because battery chemistry, unlike Moores law, moves at a snails pace. Here is some evidence to show you the proof.

Lets examine the latest offering from the IPad3. Apple was able to increase the size of the battery in its device by about 70%. It did this by engineering a more efficient internal set-up. It did NOT increase the energy density of the individual lithium ion cells. Why was all of this done? They did it for two reasons.

4G eats batteries and that new screen hogs power. So, without engineering a better set-up, the IPad 3 would have been much larger, instead of only slightly larger.

Why is this important? If you examine a laptop, theres a reason why the battery is as large as it is relative to the device. The laptop uses significant power and lithium ion batteries are only capable of packing so much energy density into a defined space. Design engineers at Apple and Samsung know perfectly well, that asking your phone or tablet to replace that of your laptop comes with one big problem that no one has solved; namely, battery chemistry.

For a company like Apple, it truly is constrained on what it can do moving forward with the Ipad and the Iphone franchises. Computing power comes at a price in small packages and with the latest revelation that energy densities did not improve, an investor might conclude that the next iterations will have to contain extraordinary software rather than hardware developments.

Oh and it is for this reason that this author believes Apple is tackling the TV market next. Stay tuned.

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Guest Post: Apple Succumbs To Battery Chemistry?

Chemistry sets 'Bent' afire

Posted on March 20, 2012 by Danzig

LOS ANGELES -- As executive producer of the new NBC comedy"Bent," Tad Quill is responsible for everything from writing the first episode to making sure the caterer doesn't poison anyone. But his most important role may be the most underappreciated one: playing matchmaker.

Good sitcoms -- and this is one of them -- need snappy dialogue, a compelling premise and engaging characters. But the most critical ingredient is chemistry between the lead actors, especially when the story hinges on a will-they-or-won't-they relationship.

Amanda Peet plays Alex, a recent divorcee who hires a gambling addict, Pete (David Walton), to remodel her house. You've seen this setup before -- she's cautious, he's wild; she's responsible, he's unreliable -- but it more than holds up because the two banter like a modern-day Cary Grant and Rosalind Russell.

You're 99.9 percent sure they'll end up in each other's arms, but watching them do the long, slow dance to get there is still a treat.

Peet, who was attached to the project from the start, read with about 20 actors and Quill saw more than 50 guys before casting Walton, who starred in the short-lived sitcoms"Perfect Couples"and "100 Questions."

"You know when it's right instantaneously," Quill says. "It's one thing to have actors saying a joke that's kind of funny, but when two people who really know what they're doing come together, you can be laughing out loud."

Walton isn't sure what makes this partnership work so well.

"Chemistry, like in real life, is hard to put words around," he says.

It helps to work with Peet, who has previously sizzled with Bruce Willis and John Cusack. She specializes in tough, intelligent characters who slowly reveal their vulnerabilities, fears and a desperate need for something more intimate than a handshake.

"It's not something I think about or set out to accomplish," Peet, whose last series, Aaron Sorkin's "Live From the Sunset Strip," also called for romantic electricity, says. "Tad's script has a lot of sexual tension and sexual suspense. You just play that."

CHEMGEN Pharma International, a Dr. Kali Pradip Chaudhuri Company, Appoints Dr. Debasis Das as General Manager of …

Posted on March 21, 2012 by Danzig

KOLKATA, India--(BUSINESS WIRE)--

CHEMGEN Pharma International, solely owned by Dr. Kali Pradip Chaudhuri, a Contract Research Organization serving the global pharmaceutical and biotechnology companies with innovative chemistry expertise, announced the appointment of Dr. Debasis Das as the company's General Manager of Business Development. Dr. Das will be heading the business development department with focus on driving economic growth including acceleration of sales and marketing initiatives to expand the company's footprint in the global market.

With extensive experience in both the pharmaceutical industry and academia, Dr. Das brings to Chemgen Pharma expertise in the fields of medicinal chemistry, synthetic organic chemistry, custom synthesis and custom manufacturing. Dr. Das' knowledge gained from supporting a wide range of projects around the world and his overall capabilities to help create innovative solutions to meet customers' expectations will be a great asset to Chemgen Pharma.

Before joining Chemgen Pharma, Dr. Das returned to India from Shanghai after his four years of service at Wuxi AppTec Co. Ltd. where he served as Associate Director in the medicinal chemistry department. Prior to WuXi, Dr. Das held various positions in contract research organizations and pharmaceutical companies in India including Dr. Reddys Research Foundation, Chembiotek Research International and Jubilant Chemsys. His impressive experience includes management, mentoring and training a large number of Ph.D. and M.Sc. scientists and chemists, overseeing research and development, managing integrated drug discovery and collaboration projects with partners from the USA and Europe.

Dr. Das holds a Ph.D. in synthetic organic chemistry from Jadavpur University and was engaged in a post doctoral research at Duke University with international publications. Dr. Das is also involved with the University colleges as a guest faculty and teaching postgraduate students on the topics of Bioactive organic compounds, Antibiotics and Aromaticity.

About CHEMGEN Pharma International

CHEMGEN Pharma International is a Contract Research Organization serving the global pharmaceutical and biotechnology companies with innovative chemistry expertise, reliable and flexible resources. Since its inception in 2004, Chemgen Pharma has built a state-of-the-art infrastructure with highly experienced and committed team members to deliver superior quality services and competitive pricing to its customers worldwide - enabling them to operate efficiently and profitably.

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