Covance Appoints Dr. Steve Street to Lead Worldwide Safety Assessment and Pharmaceutical Chemistry Services

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PRINCETON, N.J., June 18, 2012 /PRNewswire/ -- Covance Inc. (CVD) today announced that Steve Street, Ph.D., has joined the company as Global Vice President and General Manager, overseeing Covance's worldwide safety assessment and pharmaceutical chemistry services. He will be based in Harrogate, UK.

Dr. Street, with more than 27 years of experience in biopharmaceutical R&D, joins Covance from Pfizer, Inc., where he served as Vice President and Head of two global R&D units the Research Centers of Emphasis and Continuous Improvement. In these roles, he led the company's high-performing technology and operations group to increased portfolio development speed and project survival, ultimately creating a positive impact across multiple therapeutic areas, including chemistry and biology outsourcing, innovation, and new indications. During his tenure at Pfizer, Dr. Street also served as Head of the company's Worldwide Chemistry Discipline.

"Steve's keen strategic insights and exceptional R&D background will benefit Covance as we refine our global presence and strengthen our scientific expertise in early development," said Deborah Tanner, Executive Vice President and Group President, R&D Laboratories, Covance. "Science is at the core of everything we do, and the addition of a leader like Steve allows us to continue to meet clients' needs in this increasingly complex industry and, ultimately, remain the drug development partner of choice."

"Covance is known for its continuous global innovation in development, superior quality of products and services, and long-standing client relationships, all of which are essential elements for sustained success in today's highly competitive R&D landscape," said Dr. Street. "With an increasing focus on outsourcing, this is a very exciting time to transition from pharma to a contract research organization, and I am proud to join the industry leader. I look forward to learning from and working with a talented, dedicated group of new colleagues at Covance."

Dr. Street is a Fellow of the Royal Society of Chemistry, a member of the American Chemical Society, and recently served as a visiting Professor of Chemistry at the University of Nottingham, UK. He received a doctorate from Leeds University in the UK.

Covance generates more new drug development data than any other organization in the world. The company offers the industry's broadest and most integrated portfolio of R&D services, offering flexible, milestone-based solutions and full development solutions in clinical pharmacology, early clinical development, and molecule development.

About Covance

Covance, with headquarters in Princeton, New Jersey, is one of the world's largest and most comprehensive drug development services companies, with annual revenues greater than $2 billion, global operations in more than 30 countries, and more than 11,000 employees worldwide. Information on Covance's products and services, recent press releases, and SEC filings can be obtained through its website at http://www.covance.com.

Forward Looking Statements

Statements contained in this press release (and in the webcast announced in this press release), which are not historical facts, such as statements about prospective earnings, savings, revenue, operations, revenue, earnings growth, and other financial results are forward-looking statements pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. All such forward-looking statements including the statements contained herein regarding anticipated trends in the Company's business are based largely on management's expectations and are subject to and qualified by risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements. These risks and uncertainties include factors described in the Company's filings with the Securities and Exchange Commission including its Annual Report on Form 10-K and Quarterly Reports on Form 10-Q. The Company undertakes no duty to update any forward looking statement to conform the statement to actual results or changes in the Company's expectations.

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Covance Appoints Dr. Steve Street to Lead Worldwide Safety Assessment and Pharmaceutical Chemistry Services

Stars need to work on chemistry

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Select a Publication: N E W S P A P E R S ---------------------------------------------- ---Alberta--- Airdrie - Airdrie Echo Banff - Banff Crag and Canyon Beaumont - Beaumont News Calgary - The Calgary Sun Camrose - Camrose Canadian Canmore - Canmore Leader Central Alberta - County Market Cochrane - Cochrane Times Cold Lake - Cold Lake Sun Crowsnest Pass - Crowsnest Pass Promoter Devon - Dispatch News Drayton - Drayton Valley Western Review Edmonton - Edmonton Examiner Edmonton - The Edmonton Sun Edson - Edson Leader Fairview - Fairview Post Fort McMurray - Fort McMurray Today Fort Saskatchewan - Fort Saskatchewan Record Grande Prairie - Daily Herald Tribune Hanna - Hanna Herald High River - High River Times Hinton - Hinton Parklander Lacombe - Lacombe Globe Leduc - Leduc Representative Lloydminster - Meridian Booster Mayerthorpe - Mayerthorpe Freelancer Nanton - Nanton News Peace Country - Peace Country Sun Peace River - Peace River Record Gazette Pincher Creek - Pincher Creek Echo Sherwood Park - Sherwood Park News Spruce Grove - Spruce Grove Examiner Stony Plain - Stony Plain Reporter Strathmore - Strathmore Standard Vermilion - Vermilion Standard Vulcan - Vulcan Advocate Wetaskiwin - Wetaskiwin Times Whitecourt - Whitecourt Star ---Manitoba--- Altona - Alton Red River Valley Echo Beausejour - Beausejour Review Carman - Carman Valley Leader Gimli - Interlake Spectator Lac Du Bonnet - Lac Du Bonnet Leader Morden - Morden Times Portage la Prairie - Portage Daily Graphic Selkirk - Selkirk Journal Stonewall - Stonewall Argus and Teulon Times Winkler - Winkler Times Winnipeg - The Winnipeg Sun ---Ontario--- Amherstburg - Amherstburg Echo Bancroft - Bancroft this Week Barrie - Barrie Examiner Barry's Bay - Barry's Bay this Week Belleville - Intelligencer Bradford - Bradford Times Brantford - Expositor Brockville - The Recorder & Times Chatham - Chatham Daily News Chatham - Chatham This Week Chatham - Today's Farmer Clinton - Clinton News-Record Cobourg - Northumberland Today Cochrane - Cochrane Times Post Collingwood - Enterprise Bulletin Cornwall - Standard Freeholder Delhi - Delhi News-Record Dresden - Leader Spirit Dunnville - Dunnville Chronicle Elliot Lake - Standard Espanola - Mid-North Monitor Fort Erie - Times Gananoque - Gananoque Reporter Goderich - Goderich Signal-Star Grand Bend - Lakeshore Advance Haliburton - Haliburton Echo Hanover - The Post Ingersoll - Ingersoll Times Innisfil - Innisfil Examiner Kapuskasing - Kapuskasing Northern Times Kenora - Kenora Daily Miner and News Kenora - Lake of the Woods Enterprise Kincardine - Kincardine News Kingston - Frontenac This Week Kingston - Kingston This Week Kingston - Kingston Whig Standard Kirkland Lake - Northern News Leamington - Leamington Post Lindsay - The Lindsay Post London - The London Free Press London - The Londoner Lucknow - Lucknow Sentinel Midland - Free Press Minden - Minden Times Mitchell - Mitchell Advocate Napanee - Napanee Guide Niagara-on-the-Lake - Niagara Advance Niagara Falls - Review Niagara Falls - Niagara Shopping News Niagara Falls - W. Niagara Community Newspapers North Bay - North Bay Nugget Northumberland - Northumberland Today Norwich - Norwich Gazette Orillia - Packet and Times Ottawa - The Ottawa Sun Owen Sound - Sun Times Oxford - Oxford Review Paris - Paris Star Online Pelham - Pelham News Pembroke - Daily Observer Peterborough - Peterborough Examiner Petrolia - Petrolia Topic Picton - County Weekly News Port Colborne - Inport News Port Hope - Northumberland Today Port Elgin - Shoreline Beacon Sarnia - Observer Sarnia - Sarnia This Week Sault Ste Marie - Sault Star Sault Ste Marie - Sault This Week Seaforth - Seaforth Huron Expositor Simcoe - Simcoe Reformer St. Catharines - St. Catharines Shopping News St. Catharines - Standard St. Thomas - St. Thomas Times-Journal Stirling - Community Press Stratford - The Beacon Herald Strathroy - Strathroy Age Dispatch Sudbury - Sudbury Star Thorold - Thorold News Tillsonburg - Tillsonburg News Timmins - Daily Press Timmins - Timmins Times Toronto - The Toronto Sun Trenton - Trentonian Wallaceburg - Wallaceburg Courier Press Welland - Tribune Welland - Welland News West Lorne - The Chronicle Wiarton - Wiarton Echo Woodstock - Sentinel Review ---Saskatchewan--- Meadow Lake - Meadow Lake Progress Melfort - Melfort Journal Nipawin - Nipawin Journal MAGAZINES & SPECIALTY PUBLICATIONS --------- Biz Magazine Business London Cottage Home and Property Showcase Food and Wine Show Hamilton Halton Weddings Hamilton Magazine InterVin International Wine Awards Kingston Life London Citylife Muskoka Magazine Muskoka Trails Niagara Food and Wine Expo Niagara Magazine Ontario Farmer Ontario Golf Sault Good Life Simcoe Life The Home Show Vines Magazine What's Up Muskoka

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Stars need to work on chemistry

Cytec Wins EPA Presidential Green Chemistry Award

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Cytec Wins EPA Presidential Green Chemistry Award

Woodland Park, New Jersey, June 18, 2012 - Today, Cytec Industries Inc. (CYT) was awarded the top honor in green chemistry, the Presidential Green Chemistry Challenge Award. The award, created by the Environmental Protection Agency (EPA), recognizes companies that have pioneered sustainable technologies that incorporate the principles of green chemistry. Cytec`s MAX HT scale control technology enables greener conditions within the Bayer process, a process used for converting bauxite ore to alumina, the primary raw material for aluminum. The innovation reduces pollution at the source in addition to reducing energy use and waste generation. "Cytec has been a pioneer in developing innovative solutions for the mining industry while maintaining a focus on sustainable technologies. We are honored to receive such a prestigious award from the EPA," said Shane Fleming, Cytec`s Chairman, President, and CEO.

Today`s green chemistry award recognizes one of the many technology innovations Cytec has achieved within its In Process Separation business segment. MAX HT Bayer Sodalite Scale Inhibitor is the first scale inhibitor product in the market for this application and solves a legacy production challenge within the alumina industry. This technology provides benefits by reducing or eliminating the scale formation in heat exchangers resulting in higher heat transfer rates while reducing energy consumption and waste generation. "The realized energy saving for the combined customers currently utilizing our MAX HT technology is approximately 47 trillion Btu, which is the equivalent of up to 8 billion pounds of carbon dioxide (CO2) not released to the atmosphere," said Martin Court, Cytec`s Vice President, In Process Separation business. Martin added, "Fewer cleaning cycles also result in a realized annual hazardous waste reduction of up to 200 million pounds in total for all of the current operations using this product."

Cytec`s sustainability strategy is focused on developing innovative and environmentally sustainable products that compete in a global economy; achieving the highest standards of safety, health and environmental stewardship and operational excellence. The company uses business-specific market drivers and best practices to drive the sustainability efforts.

Corporate Profile Cytec`s vision is to deliver specialty chemical and material technologies beyond our customers` imagination. Our focus on innovation, advanced technology and application expertise enables us to develop, manufacture and sell products that change the way our customers do business. Our pioneering products perform specific and important functions for our customers, enabling them to offer innovative solutions to the industries that they serve. Our products serve a diverse range of end markets including aerospace composites, structural adhesives, automotive and industrial coatings, electronics, inks, mining and plastics.

Contact: Jodi Allen Communications and Investor Relations (973) 357-3283

The owner of this announcement warrants that: (i) the releases contained herein are protected by copyright and other applicable laws; and (ii) they are solely responsible for the content, accuracy and originality of the information contained therein.

Source: Cytec Industries Inc via Thomson Reuters ONE HUG#1620380

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Cytec Wins EPA Presidential Green Chemistry Award

Encycle Therapeutics Launches Ground-Breaking Chemistry Platform

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Platform for cyclizing peptides promises to increase efficiency of early-stage drug discovery

BOSTON , June 18, 2012 /CNW/ - Encycle Therapeutics, a MaRS Innovation spin-off company, has created a ground-breaking chemistry platform for cyclizing peptides that promises to increase the efficiency of the early-stage drug discovery process.

Peptides have long been sought after as therapeutics due to their high specificity they can hit specific cellular targets, especially complex protein-protein interaction targets implicated in cancer, cardiovascular disease and metabolic disorders.

In their linear form, however, peptides are unstable. When used as drug-delivery agents, they break down before reaching therapeutic targets or fail to permeate cell walls, presenting a long-standing challenge to medicinal chemists.

Encycle's breakthrough chemistry platform stabilizes linear peptides for drug development by cyclizing them. This process has demonstrably increased the drug-like properties of these molecules, increasing their stability in the body and providing a higher degree of cell permeability. The platform adapts to any linear peptide input and has the power to generate libraries of compounds to facilitate drug discovery and development.

This technology, discovered in Professor Andrei Yudin 's chemistry laboratory at the University of Toronto , will be developed with the collaboration of Professor Eric Marsault, specialized in medicinal chemistry at the Institut de Pharmacologie de Sherbrooke of Universit de Sherbrooke. Together, they will demonstrate that Encycle's foundational chemistry technology functions for a wide variety of peptides and that the platform can hit therapeutic targets of interest. Encycle will then be well positioned to pursue discovery-stage relationships with the pharmaceutical partners involved in the project around targets of their choosing.

"It costs over $1 billion to bring a new drug to market under the current high through-put pharmaceutical discovery model," says Yudin, professor of Chemistry at U of T and Encycle Founder. "Instead of randomly searching millions of compounds, Encycle's platform will allow us to design a peptide molecule with small molecule properties, such as stability and cell permeability, while remaining more likely to interact with a targeted therapeutic area. In theory, this approach would save time, money and reduce overhead risk."

"The approach pioneered by Andrei Yudin is remarkable for its efficiency in the synthesis of macrocycles, which are otherwise very difficult to reach and thus difficult to exploit in drug discovery," says Marsault. "This collaboration will unlock the potential of this class and provide much-needed new classes of drug candidates able to mimic the natural structural elements of proteins."

"This innovative project is a successful result of our established commitment towards technology transfer of excellent research and partnering with the private and public sectors," says Jacques Beauvais , vice-rector of research at the Universit de Sherbrooke.

The project has received $1 million in seed funding, largely derived through The Qubec Consortium for Drug Discovery's funding programs, and has attracted interest from four pharmaceutical companies.

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Encycle Therapeutics Launches Ground-Breaking Chemistry Platform

Chemistry in its element – potassium nitrate

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The saltpetre men of the 17th century could be described as the first biochemists. But they could also be described as a ‘rowdy and undesirable’ lot, hated and feared for the disruption and distress they caused in their search for their precious namesake. Lars Ohrstrom tells the story of potassium nitrate in this week’s Chemistry in its element podcast.

 

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Click Chemistry Reagents Now Available from Alfa Aesar

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Ward Hill, MA - Alfa Aesar, a Johnson Matthey Company, is pleased to announce the addition of a variety of compounds for use in click chemistry reactions to its expanding range of bio products.

Click chemistry is a newer approach to synthesis that makes use of simple, rapid and reliable reactions. It has several benefits over other synthesis approaches such as being orthogonal to conventional methods and occurring under relatively mild conditions. These reactions also proceed with high, almost quantitative, yields. These benefits have made click chemistry reactions a popular method of introducing labels and other tags to biomolecules. The most popular click chemistry reaction is the Huisgen 1,3-dipolar cycloaddition of alkynes to azides, which is generally carried out with catalysis by copper (I), or by introduction of an azide to a strain-promoted cyclooctyne.

Alfa Aesar's click chemistry product range offers bifunctional linkers, fluorescent tags and chemical modifications that can be used with the azide-alkyne click chemistry technique.

To request a product flyer on these products or for a free copy of the full Bio product catalog, contact Alfa Aesar at 1-800-343-0660 or email info@alfa.com.

About Alfa Aesar Alfa Aesar, a Johnson Matthey Company, is a leading international manufacturer and supplier of research chemicals, metals and materials. With over 36,000 products listed in its catalogs, Alfa Aesar is the single source for customers' needs for chemicals and materials in sizes for research and scale up. The Alfa Aesar catalog carries materials for biological research, organic compounds, high purity inorganics, pure elements, alloys, precious metal catalysts, AA/ICP standards and more. Alfa Aesar has sales offices and distribution facilities throughout North America, Europe and Asia and a distributor network covering the globe.

Contact: Mara Nieuwsma Alfa Aesar, A Johnson Matthey Company Tel. 1-978-521-6414 Fax 1-978-521-6350 Email mara.nieuwsma@alfa.com http://www.alfa.com

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Click Chemistry Reagents Now Available from Alfa Aesar

Plant's Chemistry Gets Mice To Spit Seeds

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60-Second Science | More Science

Rodents feeding on sweet mignonette love the fruit, but dislike the spicy seeds. So they spit them out, thereby dispersing them--to the plant's benefit. Karen Hopkin reports.

June 14, 2012

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Plants that use animals to disperse their seeds can find themselves in a pickle. They need to make fruit tasty enough to entice the local fauna. But they also need to make sure that their animal assistants dont digest the very seeds theyre meant to spread.

In Israels Negev Desert, a plant called sweet mignonette came up with a distasteful strategy. Critters called spiny mice feed on mignonette. They love the fruit. But they hate the seeds. And so they spit them out all over the place. Just as the plant planned. Thats according to a study in the journal Current Biology. [Michal Samuni-Blank et al, Intraspecific Directed Deterrence by the Mustard Oil Bomb in a Desert Plant]

Sweet mignonette produces little black berries that house about 20 seeds apiece. Inside those seeds is an enzyme. When a berry-chomping mouse crushes a seed, the enzyme is freed up to produce compounds that taste like hot mustard. Hence, ptooey, better leaving through chemistry.

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Plant's Chemistry Gets Mice To Spit Seeds

Chemistry you can dance to

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LOS ANGELES UCLA psychobiology major Anantha Singarajah admits she disliked chemistry before taking professor Neil Garg's popular undergraduate organic chemistry course (Chemistry 14D) this quarter.

"Chem 14A was the first class I took as a first-year, and it was disheartening," she said. "By the end of 14C, I could not wait to get it over with. However, I had heard good things about 14D with Neil Garg and waited until spring quarter especially to take it with him. This class is just as amazing as everyone describes it, and now I enjoy chemistry. Professor Garg engages you, and he brings himself to your level so you achieve full comprehension. I can say that Chem 14D has been one of my favorite classes at UCLA."

You can see that joy in "Remember the Mechs," a music video that Singarajah and three of her classmates produced as an extra-credit assignment. As most undergraduates in the sciences know by now, students in Garg's course are given the option of making their own music videos about organic chemistry, with lyrics containing mostly technical information about chemical structure, reactions and synthesis.

Maria-Kassandra "Kassey" Coronel, a psychobiology major who helped create "Remember the Mechs" with Singarajah, said that because of this course, she now finds herself "falling back in love with learning."

"Who knew putting a chem spin on an old song could be so educational?" Coronel said. "What's funny is that after making the video, I realized every time the instrumental came up on my playlist, I found myself rapping my chem lyrics instead of the original ones by Fort Minor.

"Professor Garg is without a doubt the best professor I have had at UCLA. He finds revolutionary ways to combine what college students like music videos, technology and expressing ourselves with what they need to know: organic chemistry. His passion for teaching and dedication to students is such a breath of fresh air, and it really shows when so many students, like me, are even more inspired to learn. What I love most about organic chemistry is it combines problem-solving and deduction skills with creativity, and gives me that great feeling that I'm accomplishing something meaningful. Shhh! I'm an O-chem nerd at heart now! If UCLA had a chemistry minor, I would do it in a heartbeat."

When Garg gave his students the guidelines for the music video assignment, he first showed them "Chemistry Jock," a video produced by his students in 2010 that is now approaching 60,000 views on YouTube. (Its creators, Justin Banaga, Kimberly Bui and Yannick Goeb, are graduating from UCLA this month, and all will attend graduate school.) The classroom echoed with laughter throughout the video, and one student gasped, "How did they do that?"

Then they went to work. For Singarajah, Coronel, Oz Davis and Brian Dickey, that meant 6:30 a.m. meetings that resulted in "Remember the Mechs," which itself has a few "how did they do that?" moments. (The "mechs," Coronel explained, refer to the mechanisms that show the step-by-step occurrences of a particular reaction, given certain chemical conditions.)

A common reaction among people who watch the chemistry music videos made by Garg's students is, "I love them, but what do the lyrics mean?" The answer is that they are about various chemical reactions the undergraduates study in organic chemistry.

Garg said he is amazed by the quality and creativity of the videos. Among this year's best are "Payphone," by Karla Canizales, China Magno and Anuvir Singh, (with beautiful lead vocals by Canizales) and "Hey There Neil Garg" by Firuz Yumul, Aaron Lalehzarian, Neda Ghassemi and Tianna Wilson.

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Chemistry you can dance to

Green Chemistry and Engineering Conference press events

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Public release date: 14-Jun-2012 [ | E-mail | Share ]

Contact: Joan Coyle J_coyle@acs.org 202-872-6229 American Chemical Society

WASHINGTON The American Chemical Society's (ACS') 16th annual Green Chemistry & Engineering (GC&E) Conference takes place June 18-20 at the Marriott Wardman Park Hotel in Washington, D.C. This year's theme is Innovation, Jobs, Sustainability The Role of Green Chemistry.

Media registration for the GC&E Conference is complimentary for credentialed members of the news media. Media registrants have access to the breakfasts, education sessions, keynote speakers, sponsors' luncheon, exhibition, press room and opening-night reception. For complete media registration guidelines, please contact ACS GCI at 202-872-6022 or Shefali Algoo at s_algoo@acs.org.

On-site registration: Media wishing to register on-site must present valid, current media credentials (e.g., official picture identification from the employing news organization, signed letter from assignment editor on company letterhead or a bylined article from the publication). Without proper, approved credentials, on-site media registration will be denied. Marketing and public relations executives, analysts, consultants, authors and researchers may not register as media.

Press briefings will be held in the Marriott's Jefferson Room. Media can also participate via live webcast, or they can view the archive later at the same site.

Tuesday, June 19, Morning Press Briefings: Innovation, Jobs, Sustainability The Role of Green Chemistry

Tuesday, June 19, Afternoon Press Briefings: Innovation, Jobs, Sustainability The Role of Green Chemistry

Wednesday, June 20, Afternoon Press Briefings: Innovation, Jobs, Sustainability The Role of Green Chemistry

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Green Chemistry and Engineering Conference press events

Production Chemistry Management Specialist

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Chevron Corporation is one of the world's leading integrated energy companies with subsidiaries that conduct business across the globe. The company's success is driven by the ingenuity and commitment of approximately 62,000 employees who operate across the energy spectrum. Chevron explores for, produces and transports crude oil and natural gas; refines, markets and distributes transportation fuels and other energy products and services; manufactures and sells petrochemical products; generates power and produces geothermal energy; and develops and commercializes the energy resources of the future, including biofuels and other renewables. Chevron is based in San Ramon, California.

Chevron Energy Technology Company is accepting online applications for the position of Production Chemistry Management Specialist located in Houston, TX.

Overview:

This position will have responsibilities for monitoring, diagnosing and treating oilfield production problems, developing and optimizing chemical treatment programs, and working closely with operating assets and chemical service company personnel. This position will be based in Houston, Texas and will report to head of the Production Chemistry Team.

Responsibilities for this position may include but are not limited to:

Provides technical support for major capital projects by developing recommendations for fluid sampling, fluid and chemical analyses, and chemical treating and performance monitoring as part of the system design and development

Provides guidance to both capital projects and existing fields on the selection and qualification of production chemicals. This includes recommending appropriate test methodologies/protocols and providing oversight of chemical vendors' chemical selection process

Provides consultation to operating assets in diagnosing chemical related issues and providing reliable and cost-effective chemical solutions

Works with operating assets and chemical vendors to develop chemical management programs, and optimize chemical treatments and performance monitoring

Develops proposals for funding from operating assets/business units

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Production Chemistry Management Specialist

Peter Carey's The Chemistry of Tears

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Author Peter Carey starts every novel with the big argument what is wrong with the American approach to democracy in Parrot and Olivier in America; how do Australians live with the convict stain in The True History of the Kelly Gang.

In his most recent novel, The Chemistry of Tears, he's concerned with nothing less than the fate of the earth. The story of a contemporary museum curator who is restoring an automaton a clockwork silver swan takes place in 2010, the year the BP oil spill threatened environmental disaster in the Gulf of Mexico. A parallel story takes place in the 19th century as Henry Brandling struggles to get the swan made as a gift for his consumptive son.

If you ask why are you interested in the 19th century, I would say, because were living in it, Carey said in an interview with CBC News. Were living with the consequences of it. We argue with the 19th century capitalists, growth is good we still talk like that

At the same time we know that growth is killing us. At the same time, we know were living on the resources of a planet and a half. The system will break with all the destruction man can do. So in both those cases were living in the 19th century were living in 19th century with its mad, technological optimism. We have the idea that we get richer by making stuff and then throwing it away.

The prophet that Carey gets to carry his message in The Chemistry of Tears is Amanda Snyde a crazy young woman who is off her medication and who may also be a spy for the powerful manager of the fictional Swinburne Museum in London, where much of the story is set. Amanda is obsessed with the Gulf oil spill, transfixed by the webcam that shows the stain spreading across the ocean. She sees it as an end-of-days event, but then, she also believes that the internal combustion engine is the work of aliens, who bequeathed it to humankind to lead us toward self-destruction.

Shes nuts, but shes correct, Carey says, waggishly, adding that he had to make her unhinged because I wanted someone who could give a poetic expression of a bigger truth.

Carey is Australian born the youngest son of a man who ran a car dealership and admired Henry Fords invention. Carey himself has made his home in New York for the past 22 years, teaching creative writing. now at Hunter College. Hes won the Booker Prize twice, for Oscar and Lucinda and The True History of the Kelly Gang. The Chemistry of Tears is his 18th book.

The main contemporary character, the curator Catherine Gehrig, is the first Carey conceived and the woman who provided a narrative arc to the story he tells. Shes been in a secret affair with a married man and he dies, leaving her so paralyzed by grief she does not trust her own judgment. She cannot grieve openly, and her behaviour is so erratic she is moved to an annex of the Swinburne Museum and given a project meant to keep her out of harms way to reconstruct an automaton that arrives packed in pieces in numerous tea chests.

Im really very fond of her, Im fond of all my characters. I find her behaviour totally reasonable, Carey says of Catherine, who is more concerned about breaking into her lovers account and deleting all the e-mails theyve exchanged than with her odd assistant, Amanda, or with her job. Ive never experienced what Cat did, but I have loved someone. Its not hard to imagine.

The 19th century character Henry Brandling who seeks out a clockmaker in Karlsruhe, Germany to make an automaton is equally perturbed by grief, both for his failed marriage and over the illness of his child, Percy. Brandling has found a drawing of Vaucansons duck, an automaton that eats and excretes, by the real French inventor Jacques de Vaucanson. He wants a similar device for his consumptive son, thinking that it will make the boy laugh and encourage him to live.

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Peter Carey's The Chemistry of Tears

FIFA 12: Exploring The Individual Player Chemistry Myth – Video

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13-06-2012 10:29 Wanted to test it out and prove that individual player chemistry does not make a difference on the performance. If you want me to continue this, let me know. ----------------------------------------------------------------------------- Follow Me: Subscribe To My 2nd Channel: Become A Fan: Follow My channel: Get A TROUTED T-shirt At: Make A Fantasy Premier League Team Here http & Then Join My League With This Code: 1241775-282939 Get your Kontrol Freek's here (for 10% off, promo code: TROUT):

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FIFA 12: Exploring The Individual Player Chemistry Myth - Video

Sutro Licenses "Click Chemistry" from The Scripps Research Institute

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SAN FRANCISCO, June 14, 2012 /PRNewswire/ --Sutro Biopharma today announced that it has signed a licensing agreement with The Scripps Research Institute and will have access to "click chemistry," a modular synthetic approach that allows the assembly of new molecular entities by efficiently and reliably joining two molecular units together stably and irreversibly. The agreement with Scripps Research provides Sutro with a worldwide license to apply click chemistry for the synthesis of novel therapeutic protein candidates by utilizing Sutro's biochemical protein synthesis platform to incorporate one or more of the "click" components into a peptide or protein chain.

The click chemistry approach was developed by Nobel Laureate K. Barry Sharpless, Ph.D., the W.M. Keck professor of chemistry at The Scripps Research Institute, and describes synthetic chemistry tailored to generate substances. This is done by joining, or clicking, reactive molecular building blocks together selectively and covalently. Click chemistry allows the further design of different types of therapeutic agents, including antibody therapeutics, peptide therapeutics and various small molecules.

"Combined with Sutro's powerful platform, 'click chemistry' will further extend our capability to engineer customized therapeutics with pharmacologic properties that are optimized for each specific application," said Trevor Hallam, Ph.D., chief scientific officer of Sutro. "The agreement will expand our armamentarium as we continue to develop novel protein therapeutics with our partners and advance our own pipeline of next-generation antibody drug conjugates."

The financial terms of the agreement were not disclosed.

About The Scripps Research Institute

The Scripps Research Institute is one of the world's largest independent, not-for-profit organizations focusing on research in the biomedical sciences. Over the past decades, Scripps Research has developed a lengthy track record of major contributions to science and health, including laying the foundation for new treatments for cancer, rheumatoid arthritis, hemophilia, and other diseases. The institute employs about 3,000 people on its campuses in La Jolla, CA, and Jupiter, FL, where its renowned scientists -- including three Nobel laureates -- work toward their next discoveries. The institute's graduate program, which awards Ph.D. degrees in biology and chemistry, ranks among the top ten of its kind in the nation. For more information, see http://www.scripps.edu

About Sutro Biopharma

Sutro Biopharma, located in South San Francisco, is developing anew generation of antibody drug conjugate therapeutics and bifunctional antibody-based therapeutics for targeted cancer therapies. These therapeutics will significantly extend the clinical impact of current oncology therapeutic approaches and are beyond what can be envisioned with current (cell-based) expression technologies. Sutro's biochemical synthesis technology, which underpins these therapeutics, allowsthe rapid and systematic exploration of many protein drug variants to identify drug candidates. Our make-test cycle for hundreds of protein variants, including those incorporating non-natural amino acids, takes approximately two weeks.Once these product candidates are identified, production can be rapidly and predictably scaled up to commercial levels. In addition to developing its own drug pipeline, Sutro Biopharma is collaborating with select pharmaceutical and biotech companies in the discovery and development of novel protein therapeutics. For more information, visit http://www.sutrobio.com.

Media Contacts:

David Schull or Martina Schwarzkopf, Ph.D. Russo Partners (212) 845-4271 (212) 845-4292 (347) 591-8785 (mobile) david.schull@russopartnersllc.com martina.schwarzkopf@russopartnersllc.com

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Sutro Licenses "Click Chemistry" from The Scripps Research Institute

Royal Society of Chemistry Selects Neolane for Marketing Automation

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TWICKENHAM, England--(BUSINESS WIRE)--

Conversational marketing technology provider Neolane today announced the Royal Society of Chemistry (RSC) in the United Kingdom as a new customer. The organisation will implement the Neolane Leads marketing automation software platform to improve the effectiveness of its publishing and membership marketing activities and to alert members, readers and authors to new content, activities and events specifically relevant to them.

We considered marketing automation to help us form better and higher value relationships with members, authors and readers through understanding and serving their specialised interests more closely, said Richard Crouch, marketing director at the Royal Society of Chemistry. Neolane Leads will help us define complex communication workflows and then engage in automated one-to-one conversations cost-effectively, cross-channels including via social media.

He continued: Sophisticated analysis and reporting capabilities within Neolane will help us to optimise marketing effort and the value of the communications we send to each customer, whilst excellent data protection capabilities will ensure customers details are kept secure.

RSC operates in a business to business to consumer (B2B2C) environment where customers are both companies and institutions and the scientists, information professionals and students that work or study there. Neolane Leads will collect campaign responses and inbound data from web forms and events, automatically fulfil requests for marketing collateral and content and update profiles in the single customer view. Later on, RSC will also use the platform to score and track leads from inception through to maturity, integrating it with the societys sales force automation system. As leads become hot prospects, they will then be passed directly to relevant sales teams for conversion.

Neolane Leads addresses the full breadth of marketing needs spanning demand generation, customer communications, and lead management, said Martin Smith, head of marketing Neolane (UK). In a single application, RSC will be able to feed, visualise, and monitor its marketing pipeline, plan and execute demand generation, implement customer communications programmes, and nurture leads all while demonstrating revenue accountability.

About Neolane

Neolane provides the only conversational marketing technology that empowers organizations to build and sustain one-to-one lifetime dialogues, dramatically increasing revenue and marketing efficiency. Born digital, withbest-in-class email and inbound-outbound channel fusion capabilities architected into a single code-based platform, marketers achieve results in record time. Neolane is easy to use for both power and casual users, but powerful enough to drive the most sophisticated marketing strategies. Future proof, Neolane has a track record of enabling its customers to adapt to new customer engagement challenges and exploit opportunities more quickly than their competition.Neolane is used by more than 350 of the worlds leading companies including Alcatel Lucent, barnesandnoble.com, Orange, Sears Canada, Sephora Europe and Sony Music. Visit http://www.neolane.com and read our blog The Cross-Channel Conversation.

About the Royal Society of Chemistry

The Royal Society of Chemistry is the UK Professional Body for chemical scientists and an international Learned Society for the chemical sciences with more than 48,000 members worldwide. It is a major international publisher of chemical information, supports the teaching of chemical sciences at all levels and is a leader in bringing science to the public. http://www.rsc.org

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Royal Society of Chemistry Selects Neolane for Marketing Automation

UCB and ChemDiv Research Institute Conclude First Phase of Discovery Chemistry Collaboration

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SAN DIEGO, CA and BRUSSELS, BELGIUM and MOSCOW--(Marketwire -06/13/12)- UCB and ChemDiv have successfully concluded the first phase of their 2011 collaborative discovery chemistry program executed with ChemDiv's Moscow subsidiary, the ChemDiv Research Institute.

In the course of the collaboration, ChemDiv prepared hundreds of complex and highly targeted medicinal chemical scaffolds, building blocks and templates as part of a complete discovery chemistry solution. The partners' joint steering committee review of progress milestones confirmed the success of the ongoing collaboration, which carries an initial term of 2 years, and can further be extended.

UCB's Benoit Kenda remarked, "UCB had been looking for a partner that has a very strong standing in scaffolds ideation, library preparation and could contribute to UCB's already large and diverse compounds library, in particular in developing special libraries, according to UCB's specifications, and need to inhibit novel Biotargets. We are very happy to have found a partner with ChemDiv which is equally strong in developing novel scaffolds and templates.

Dmitry Kravchenko, CEO of ChemDiv Research Institute, said: "We are pleased that our collaboration with UCB proceeds with continuing success, as acknowledged by both parties. Our success in developing this comprehensive chemistry solution for UCB was enabled by ChemDiv's proprietary Chemistry On Demand design and development system, which encompasses over 2B of druggable, target-relevant and validated structure/synthetic space. We are committed to further extending our collaboration with UCB as a long term relationship."

About ChemDiv Research Institute:

ChemDiv and the ChemDiv Research Institute (CDRI) comprise a fully integrated discovery and development CRO based in San Diego and at the ChemRar High Tech Center in Moscow. CDRI collaborates with pharmaceutical and biotech partners by enabling them to accelerate R&D programs to higher value clinical inflection points. ChemDiv and its CDRI subsidiary offer integrated Discovery outSource solutions covering the complete range of disciplines, in multiple therapeutic areas (CNS, oncology, inflammation, metabolic, infectious diseases, and others), from discovery research and preclinical development, through accelerated Proof of Concept, and to market registration.

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UCB and ChemDiv Research Institute Conclude First Phase of Discovery Chemistry Collaboration

4 hospitalized after breathing high school chemistry fumes

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Two students and two staff memberhave been taken to hospitals after a chemistry experiment gone wrong sent fumes into the air and forced a North Hollywood high school to evacuate the campus.

Students were released from their East Valley High gymnasium at 3:22 p.m. Monday at normal dismissal time, according to Los Angeles Unified spokeswoman Monica Carazo. She said the entire student body of 900was evacuated and four people were taken to hospitals as a precautionary measure.

The students and staff members who were hospitalized hadcomplained of dizziness, headaches and respiratory irritation, according to Los Angeles Fire Department spokesman Brian Humphrey. The victims included the chemistry teacher, he said, awoman in her 30s.

Fire officials responded to a call about 12:52 p.m. after the teacherapparently mixed two substances incorrectly, authorities said.

Officials said the teacher had performed the experiment in her third-floor chemistry class in the morning and it had gone well. In the afternoon, however, she mixed nitric acid and sugar rather than the intended sulfuric acid and sugar. The misstep caused reddish-brown clouds to form, prompting the evacuation, Carazo said.

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4 hospitalized after breathing high school chemistry fumes

Andrew Garfield on 'Amazing Spider-Man' chemistry with Emma Stone

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Sweet and sought after, young Hollywood stars Andrew Garfield and Emma Stone are speaking out about their chemistry onscreen, that is, in "The Amazing Spider-Man."

While the two keep a low profile in their personal relationship (sparked last June), the actors bring some theatrical heat as lovebirds Gwen Stacy and Peter Parker.

"We got on really well as people, in between [takes]," Garfield told MTV News. "That was the fun stuff. In between, we'd just mess around, and I felt, 'Ah, this is different.'"

Garfield expressed relief that Stone decided to take the role, saying that his scenes with the"Crazy Stupid Love"actress were his favorite to shoot (watch the interview below).

"Those were the days I would look forward to. For Peter as well. Because Peter goes through some horrible stuff in the movie. There's some joy to be had when experiencing his first love," Garfield said.

Stone echoed his sentiments, saying that mutual attraction is instinctive.

"The Amazing Spider-Man" swings into theaters July 3. Next up for Stone is the period drama "Gangster Squad," alongside Sean Penn and Ryan Gosling. Garfield just finished his run in Mike Nichols' Tony Award-winning Broadway revival of"Arthur Miller's Death of a Salesman."

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Andrew Garfield on 'Amazing Spider-Man' chemistry with Emma Stone

Teacher named national award winner

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WASHINGTON, D.C. - A chemistry teacher at Appleton East High School is receiving recognition from President Barack Obama.

Kara Pezzi will receive a Presidential Award for Excellence in Mathematics and Science Teaching later this month in Washington, D.C.

"This is an incredible, it's an incredible experience," said Kara Pezzi.

Pezzi has been teaching for twenty years, at Appleton West and Wautoma before East, but has never received this kind of attention.

"I've gotten Wisconsin awards but nothing like this," Pezzi explained.

Recently, Pezzi became one of 97 teachers nation wide to receive the award.

Organizers say the Presidential Award for Excellence in Mathematics and Science Teaching is awarded annually to outstanding K-12 science and mathematics teachers from across the country.

In a statement, President Obama says," These teachers are the best of the best, and they stand as excellent examples of the kind of leadership we need in order to train the next generation of innovators and help this country get ahead."

"I can't think of a more deserving teacher we have on our staff," said Appleton Superintendent Lee Allinger. "She's a person who lives and breathes science education and what a tremendous role model not only for our district but for young people that might be considering a field in education."

Pezzi began the application process back in 2010.

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Teacher named national award winner

American Chemistry Council Applauds Linde on Responsible Care® Achievements

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MURRAY HILL, N.J. & NEW PROVIDENCE, N.J.--(BUSINESS WIRE)--

Linde North America has received a commendation by the American Chemistry Council (ACC) for its role in helping ACC meet industry-wide safety and product stewardship targets through its Responsible Care Performance Award program. ACC recognized Linde at its 21st annual Responsible Care Conference, which highlights the industrys world-class environmental, health, safety and security performance initiative.

Linde North America is a member of The Linde Group, a world-leading gases and engineering company. The American Chemistry Council (ACC) is an association of producers, manufacturers and suppliers of chemical products. Since 2008, Linde North America has received certification at 21 of its operations facilities, as well as at its corporate headquarters in Murray Hill, New Jersey, under ACCs Responsible Care program.

Responsible Care is a globally recognized management system aimed at helping companies improve performance in areas such as safety, health, environment and security. Certification is mandatory for all ACC member companies, which must undergo headquarter and facility audits by an independent, accredited auditor to verify that they have a structure and system in place that manages and measures performance. Lloyds Register Quality Assurance (LRQA) is Lindes independent auditor.

Patrick Murphy, president of Linde North America, which has been a member of ACC for over 60 years, said, We are extremely proud to receive this recognition from the ACC. We are committed to the Responsible Care program and retaining our membership in the American Chemistry Council. While it is a painstaking process to meet all the criteria for these awards, it is a very rewarding experience. Working toward and receiving Responsible Care certification falls right in line with our goals as a high performance organization and our vision to be the leading gases and engineering company.

The Responsible Care Performance Award recognizes companies with significant achievements in occupational safety and product safety communications. These companies are leading the ACC membership in improved safety performance and public communications about the safety of chemical products, said Debra Phillips, managing director of ACCs Responsible Care Program. We are pleased to recognize Linde North America for its commitment and dedication to the health, safety and security of their workers, their facilities, and the communities in which they operate.

The Responsible Care management system offers an integrated, structured approach for driving continual improvement in seven key areas: community awareness and emergency response; security; distribution; employee health and safety; pollution prevention; process safety; and product stewardship.

The Linde Group is a world-leading gases and engineering company with around 50,500 employees in more than 100 countries worldwide. In the 2011 financial year, it achieved sales of EUR 13.787 bn (USD 18.1 billion). The strategy of The Linde Group is geared towards long-term profitable growth and focuses on the expansion of its international business with forward-looking products and services. Linde acts responsibly towards its shareholders, business partners, employees, society and the environment in every one of its business areas, regions and locations across the globe. The Group is committed to technologies and products that unite the goals of customer value and sustainable development.

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American Chemistry Council Applauds Linde on Responsible Care® Achievements