![]() Reuters UK | Don't Call It 'Pot' in This Circle; It's a Profession New York Times Varieties of medical marijuana were on view in a glass-covered display case at the Harborside Health Center. As more and more states allow medical use of ... The Drug-Free Workplace vs. Medical MarijuanaNBC Miami Business Model Debate: Big Tobacco Vs. Big PharmaNBC San Diego Will the Bear Market End the "War on Drugs"?Elliott Wave CounterPunch -New York Times all 73 news articles » |
Nityananda bound devotees with non-disclosure agreements – Sify
![]() Oneindia | Nityananda bound devotees with non-disclosure agreements Sify ... had tried to secure himself from any legal action by making his devotees sign papers agreeing to sexual acts as part of rituals to attain enlightenment. ... Godman, conmanDeccan Herald Swami Nityananda Paramahamsa Scandal: Girls Forced to Sign Sexual DealGanpati News (blog) |
Medical Officer backs sex education for kids – Toronto Sun
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UW Medical School Investigating Stripper At Event – WISC Madison
UW Medical School Investigating Stripper At Event WISC Madison The University of Wisconsin-Madison School of Medicine is investigating a university-sanctioned event where a group of medical students paid a stripper to ... UW School of Medicine officials investigating stripper at school-sanctioned ...FOX6Now.com Milwaukee UW investigates strip show at Memorial UnionWKOW-TV.com |
ad:tech Panel: Developing Communities Online
I recently moderated a great panel at ad:tech about how businesses build communities for their brand online. I was joined by John Duncan, president of eSolutions, a digital agency; Alan Masarsky, vice president of marketing for Clipta, a video search engine; and Steve Koskie, CEO of Dipdive, a new media network that features and supports artists of all kinds.
The panel discussed the impact large social media networks – particularly Facebook – and newer technologies like video are having on the way the users experience the Internet. With the evolution of these two Web phenomena, user engagement becomes the key to online success. Each panelist brings a fresh perspective about what that means for businesses and how entrepreneurs can effectively create and engage communities of users:

[See post to watch the Flash video]
What I found most interesting was the agreement that traditional agencies must rapidly evolve or die. Older, integrated, non-specialized agencies are having a hard time accommodating the diversity of customer interactions online, given the changing metrics associated with customer engagement and the drive to move customers not just to loyalty but to advocacy.
The Internet is now a tangled web of interactions and opportunities. Companies like Dipdive, Clipta and eSolutions recognize the importance of targeting specific audiences and setting goals based on user engagement. Businesses should leverage the resources available to them when those resources serve a strategic purpose. If you rush to create a Twitter feed, YouTube channel, blog, Facebook page, etc. without considering how those tools enhance your message, you may do more harm than good.
Dipdive creates entire communities around artists, Clipta increases the visibility of the rich range of video on the Web, and eSolutions helps businesses create unique brands and communities. Each company brings a different approach to the table, and each of the approaches is proven to be successful. You won’t find a one-size-fits-all solution, so the key is to understand your needs and capabilities to produce the results you’re looking for.
I’d like to extend my personal thank you to the panel for your time and insightful comments … and your business with The Planet.
If any blog readers out there have thoughts on the topic of community building or the evolution of the Web as an engaging marketplace, please feel free to share them here!
-Lewis
Related Posts:
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24°19`N 120°40`E

Allison and Jeremiah felt the “best way to see the world on a teacher’s salary, and continue doing what they loved (travel), was to teach abroad”. They packed they bags and headed to Taiwan. Their adventure has just begun. Where it will lead? Well, not even they can say but it’s sure to be exciting.
© Gretchen for TravelBlogs, 2010. |
24°19`N 120°40`E |
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Post categories: Blogs
Post tags: activism, Asia, cultural experiences, expat blog, expat life, Taiwan, teaching
NOTICE: A Cheat Sheet for 2010 Candidate Forms. What’s a CFA 1 Anyways?
This legal jargon may sound intimidating, but it amounts to less than 15 minutes of filling out simple forms to place you on the Indiana ballot as a Libertarian. We want you to know exactly when and where to file so you can get and stay on the ballot. We have many experienced party members [...]
Blood Test Meant To Analyze Genetic Activity Could Replace Biopsies After Heart Transplantation
The New York Times (4/23, B5, Pollack) reports that "a blood test that analyzes genetic activity could let heart transplant patients avoid many of the invasive and uncomfortable biopsies now used to monitor whether their immune systems are rejecting their new organs," according to a study scheduled to be presented at the International Society for Heart and Lung Transplantation meeting and published online by the New England Journal of Medicine. The research "involved 602 patients at 13 American transplant centers who had received a transplant from six months to five years earlier." Half of the participants "were given periodic biopsies and the others the blood test," called AlloMap, "at the same frequency."
The Wall Street Journal (4/23, Winslow) reports that just under 15% of patients who were given the test died or experienced complications during the follow-up period, compared to just over 15% of patients who were given biopsies.
The Los Angeles Times (4/22, Maugh) "Booster Shots" blog reported that "the primary limitations of the study were that it did not include patients in the first months immediately after their surgery and that it probably did not include patients who were at high risk of rejection, the authors said."
The Time (4/22, O'Callaghan) "Wellness" blog reported that AlloMap "was approved by the US Food and Drug Administration in September 2008 and assesses rejection risk by examining gene expression in patients' white blood cells."
Reuters (4/23, Steenhuysen) quotes one of the researchers as saying, "This represents a major step forward in the way we manage a patient after heart transplants because we can now safely reduce the numbers of heart biopsies."
MedPage Today (4/22, Phend) reported, "Rather than suggesting that the assay should become the standard, the real implication is the evidence the study offers questioning whether any routine screening is needed over the longer term after transplantation, [John A. Jarcho, MD, of Brigham and Women's Hospital] said" in an accompanying editorial. HeartWire (4/22, Stiles) and MedWire (4/22, Price) also covered the story.
Three sensible REASONS for legalizing Marijuana
NEW FROM NICK GILLESPIE, REASON
Gillespie talks of:
1. The tax revenue and law enforcement savings.
2. It's going to happen anyway, so why delay the inevitable?
3. Keep Your Laws Off Our Bodies.
Radical Muslims now specifically targetting libertarians: Death Threats to South Park creators
South Park creators Trey Parker and Matt Stone are longtime self-proclaimed "libertarians." Indeed, Parker is actually a registered Libertarian Party member. They are friends of Reason Magazine. And they have used explicit libertarian themes in numerous episodes.
In the early 2000s, a movement was born out of their series, called "South Park Republicans." They are described as center-right Republicans, mostly suburban fans of the show, with moderate libertarian-leanings. There was even a book released by author Brian C. Anderson called "South Park Conservatives."
And now, like European Free Speech advocating Cartoonists, they have been specifically targeted with a serious Death Threat from a major Islamic Website.
From FoxNews.com "'South Park' Creators Could Face Retribution for Depicting Muhammad, Website Warns" :
A radical Islamic website is warning the creators of "South Park" that they could face violent retribution for depicting the Prophet Muhammad in a bear suit during an episode broadcast on Comedy Central last week.
RevolutionMuslim.com posted the warning following the 200th episode of Trey Parker and Matt Stone's "South Park," which included a caricature of the Prophet Muhammad disguised in a bear suit. The Web posting also included a graphic photo of Theo van Gogh, a Dutch filmmaker who was murdered in 2004 after making a documentary on violence against Muslim women.
"We have to warn Matt and Trey that what they are doing is stupid and they will probably wind up like Theo Van Gogh for airing this show," the posting reads. "This is not a threat, but a warning of the reality of what will likely happen to them."
Reaching by phone early Tuesday, Abu Talhah al Amrikee, the author of the post, said he wrote the entry to "raise awareness." He said the grisly photograph of van Gogh was meant to "explain the severity" of what Parker and Stone did by mocking Muhammad.
"It's not a threat, but it really is a likely outcome," al Amrikee said,
Ironically, both Parker and Stone were guest speakers at a conference in Amsterdam in 2006 on the topic of Free Speech Rights, sponsored by Reason. Editor Nick Gillespie said at the time:
One of the reasons we were interested in having a conference in Amsterdam is that it’s not only the birthplace of tolerance but the site of one of the most brutal crimes related to free speech in recent memory: the 2004 murder of Dutch filmmaker Theo Van Gogh, who was stabbed to death in the street after making a 10-minute film critical of Islam’s treatment of women.
Parker commented to Reason in a resulting interview, Dec. 2006 isue:
This is what happened. I was on my honeymoon in Disney World. I turned on the television, and there were thousands of rioting Muslims, and the caption said, “Muslims enraged over cartoon.” And I said, “Oh, shit. What did we do?”
We actually did an episode five years ago with Muhammad in it. It was an episode called “Super Best Friends,” and Muhammad had super powers and turned himself into a beaver and then killed Abraham Lincoln. I thought, “They finally just saw it, and they’re all pissed off.” But no, it was those other cartoons that they were mad about.
Reached for a comment, Gillespie told Libertarian Republican yesterday:
To say that semi-veiled death threats against the creators of a cartoon show that spoofed Mohammed demonstrates the need for an Islamic reformation is self-evident. The threats, especially the invocation of the brutal murder of Theo van Gogh by a religious nutbar, should shame all serious Muslims the same way the pope's behavior in sexual-abuse scandals shames true Catholics. Whether religious or secular, ideologies that try to suppress dissent and free expression through violence always lose, and always make themselves more abjectly pathetic on the road to the dustbin of history.
Editor's Note - Michael W. Dean contributed to this story.
NEW HAMPSHIRE: Good polling news for Libertarian Republicans, Guinta ahead
It's a very slender lead, but a lead none-the-less. Frank Guinta is a longtime friend of New Hampshire libertarians. In fact, there's also a rumor that he was once a dues-paying member of the Libertarian Party. He is the immediate former Mayor of Manchester. He built up a reputation of being out of the ordinary, even a bit quirky. He never compromised on taxes and budgetary matters, and in the process made a few enemies. He's also a diehard Tea Party devotee, and has spoken at numerous rallies.
Now, the very latest poll has him taking the lead over increasingly unpopular, and ultra-liberal incumbent Carol Shea-Porter. (The polling data also has moderate-to-conservative Republican, and former Representative for CD2 Charlie Bass with a comfortable lead, over the incumbent Dem; another GOP pick-up.)
From PPP (via Hedgehog):
US HOUSE – NEW HAMPSHIRE – CD1 (PPP)
Frank Guinta (R) 46%
Carol Shea-Porter (D-inc) 45%US HOUSE – NEW HAMPSHIRE – CD2 (PPP)
Charlie Bass (R) 47%
Katrina Swett (D) 32%
A victory in the CD1 race for Libertarian and Conservative Republicans will be especially sweet. Carol Shea-Porter is a particularly socialist and thoroughly unlikable figure. She has gone out of her way to antagonize the Right, particularly at Town Hall meetings.
In fact, the polling data finds her unfavorables to be very high, right at 50%, with favorables at 41%. Unfavorables that high are almost the kiss of death for any incumbent. Still, Guinta has the problem that nobody outside of Manchester knows who he is, with a 52% "no opinion."
If you're in New England, this is one race where you'll most assuredly want to donate your time and money.
NDE Update
Back in 2008 I wrote on Near Death Experiences (NDE’s). I have an interest in this topic as I have frequent exposure to near death; my wife has a predilection for watching Judge Judy. Since 2008 there have been a few studies on the topic of NDE’s as researchers try and find evidence that consciousness transcends the brain, if that is what a NDE represents. I have also been ill for most of the last week and have not had the usual time to spend generating typos to drive some readers to distraction. Fortunately, I have a miracle cure that is 100% effective in resolving all my self -limited illnesses: time. It passed and with it the illness. As a result I am about 10 days behind in the commitments in my life, so this will be a shorter than usual post.
As will come as no surprise to anyone who reads this blog regularly, I am of the opinion that NDE’s are almost certainly physiologic in origin. I see no reason why consciousness should exist beyond physiologic brain function. I am not sympathetic to the whole mind-brain dichotomy and see no reason why the mind is not the result of brain function. No one ever speaks of the lung-gas exchange dichotomy or the kidney-urine production dichotomy. But that is my bias, and I mention it at the beginning of the post in the interest of openness.
There is an enormous popular literature on NDE’s, but little in the way of science, probably, I would guess, is that it is difficult to prospectively find subjects upon which to do studies.
There are people, however, who are going to die and it is nice to allow them to go gentle into that good night. I appreciate the efforts of palliative care specialists, as while I have never particularly worried about being dead, the process of getting there has never seemed particularly inviting. Part of ensuring that patients are comfortable is to monitor their cerebral function to make sure the remain unaware. This technique was developed by anesthesiologists who did not want their patients to become conscious during surgery yet have no ability to communicate that they were now aware that their appendix was being removed.
Dying patients had their brain function monitored to make sure they remained unconscious as they died. If you decide to remove a patient from the ventilator as an example, you do not want them to be aware.
As the brain dies, there appears to be a last, short, burst of a of electrical activity.
“…loss of blood pressure, as monitored by indwelling arterial line, was followed by a decline is BIS/PSI activity followed by a transient spike in BIS/PSI activity that approached levels normally associated with consciousness. This spike in electroencephalogram (EEG) activity had short duration and the activity then declined to a level of activity associated with burst suppression.”
A last gasp of activity before the void. What is happening? What does this burst represent? Is the world being observed one last time? Does the patient see themselves from afar? Are they going to the light? Are memories reviewed or being formed? No one knows. Everyone died and are unable to report what they thought or experienced with the burst of activity. But one could speculate. And one does
“We speculate that this level of BIS/SEDline activity is related to the cellular loss of membrane polarization due to hypoxemia. We further speculate that since this increase in electrical activity occurred when there wash no blood pressure, patients who suffer “near death” experiences may be recalling the aggregate memory of the synaptic activity associated with this terminal but potentially reversible hypoxemia.”
So perhaps the NDE is the last flurry of electrical activity by the brain and, if the patient were brought back from the grave, they would recall this activity as a NDE. Or not. Like most of what occurs in the minds of the dying, it is lost to death.
NDE’s can be induced by drugs. Ketamine, an anesthetic drug, can also cause a reaction similar to an NDE. Ketamine can cause visual distortions and a lost sense of time, sense, and identity. Ketamine works as a NMDA receptor antagonist, similar to the action the more familiar drugs dextromethorphan, phencyclidine (PCP), and nitrous oxide. All these drugs can cause a dissociative state. I remember when I had nitrous oxide for my wisdom teeth extractions, I became convinced that I was not in the dental chair, but was somehow outside looking in on the oral surgery. To ‘prove’ I was in the chair, I kept lifting my hands up and waving them, to the distraction of the oral surgeon. I had a similar reaction to indomethacin, a sense that I was in the corner of the room looking down at me. It is most odd.
“We aimed here at assessing, in a sample of ketamine misusers, concordance between the typical near-death experience (NDE) features and the on-drug psychoactive effects the subjects experienced. In 2003-2005, a sample of previous ketamine misusers recollecting a ketamine-related NDE were recruited through snowballing and screened with the means of the Greyson NDE Scale; 125 participants made an initial contact with the researcher and 50 reported a minimum score of seven at the “Greyson NDE Scale”. Interviewees were in the range 21-66 years old; 27 participants (54%) were educated at BA level, 18 (36%) had an MSc, and 5 (10%) a PhD. Eight (16%) interviewees had a definite religious background. An average lifetime ketamine intake of 140 occasions was reported by the interviewees, who typically presented with a polydrug, including cannabis and MDMA/ecstasy, misuse history. In 45 (90%) cases, the NDE occurred during the first few occasions of intake. Most frequent features of reported NDE states included: altered perception of time (90%), strong sense of detaching from own physical body (88%), and a sense of peace/joy (76% of subjects). Although results here described were elicited from a self-selected, nonrandomized, limited size sample of misusers, we suggest that recreational ketamine intake may be associated with occurrence of near-death related states.”
Of course, just because James Randi can bend a spoon using prestidigitation doesn’t mean that Uri Geller isn’t bending spoons with his mind. Similarly, just because NDE’s can be mimicked in ketamine abusers, er, I mean misusers, doesn’t mean that ‘real’ NDE’s are not the consciousness going towards the hereafter. But I am an Occam kind of guy; why should entities be multiplied beyond what is necessary?
Numerous physiologic parameters go awry as you die and all your body functions fail. Many tightly controlled parameters become progressively deranged: pH, C02, sodium, etc. Could these derangement’s have something to do with the physiology of NDE’s?
In a recent study they evaluated 52 patients who survived an out of hospital cardiac arrest, of whom 11, or 21% had an NDE. As a group, the NDE’s had both higher CO2 levels and lower O2 levels in the blood. They also found increased potassium in those with NDE’s.
They note prior studies that demonstrate that low levels of oxygen can result in NDE ’s, perhaps by way of the NMDA receptor as well. Low oxygen and high CO2 may be a plausible physiologic partial explanation for NDE’s. Whether some brains are predisposed to NDE’s (since some patients had more than one, poor guys, nearly dying more than once) or there are other factors has yet to be elucidated.
The high potassium? In the discussion they comment,
“Alternative theories found the explanation for NDEs in quantum theory, which suggests that consciousness may arise from quantum processes within neuronal microtubules. The recent work of Bernroider and Roy suggests that quantum entanglement in the ion channels (especially in the potassium channel) of brain cells underlies information processing in the brain and, ultimately, also consciousness. Although untenable and purely theoretic, this possible connection between potassium channels in the brain and the mechanism of consciousness (and therefore the possible mechanism of NDEs) deserves further investigation.”
Once you invoke quantum mechanics for any process macroscopic process in medicine (except, perhaps, MRI’s), you lose credibility. Exactly why an untenable explanation deserves further investigation is not explained.
Potentially psychologic factors were not associated with NDE’s in this study. ”Sex, level of education, fear of death, time until ROSC, and religious belief” were not associated with an NDE, lending credence to that idea that NDE’s are a physiologic response rather than spiritual response, although I suspect the authors lean towards the spiritual side.
“Clearly, the presence of NDEs pushes the current knowledge of human consciousness and mind-brain relation to the edge of our understanding.”
To my mechanistic, reductionist way of thinking, NDE’s are the last gasp of activity of a dying brain. Like a cramp in an ischemic leg, it does not push the muscle-contraction relation to the edge of out understanding.
Again, association is not causation, but there is an interesting rat study that suggests that both low pH and increase C02 combine to inhibit NMDA receptors, just like ketamine.
“BACKGROUND: Carbon dioxide (CO2) dose-dependently decreases minimum alveolar concentration (MAC) of anaesthetics in rats. CO2 also dose-dependently decreases cerebrospinal fluid pH. N-methyl-D-aspartate (NMDA) channels exhibit pH sensitivity and are putative targets for inhaled anaesthetics. We hypothesized that CO2 dose-dependently decreases rat NMDA channel current via an acidifying effect at concentrations relevant to CO2 MAC.
METHODS: To test this hypothesis, we studied rat NR1/NR2A glutamate receptors expressed in voltage-clamped Xenopus oocytes. To measure pH effects, we used perfusates adjusted between 7.3 and 5.3 with HCl. To measure CO2 effects, we used equimolar sodium perfusates containing either 0 or 24 mM NaHCO3 and CO2 between 0% and 87% atm. Solution compositions were measured using a blood gas analyser with values corrected using a calibrated pH meter and gas chromatograph with solutions at 37 degrees C.
RESULTS: We found that decreasing pH decreased NMDA current. Moreover, pH effects produced by adding CO2 to NaHCO3-containing perfusates were identical to those produced by adding HCl to normal perfusates. The pH inhibiting 50% of NMDA current was 6.52. The CO2 concentration inhibiting 50% of rat NMDA current was 63% for solutions with 24 mM NaHCO3. CO2 exhibited a linear dose-dependent NMDA response analogous to that observed for in vivo CO2 anaesthetic potency in rats.
CONCLUSIONS: CO2 and hydrogen ions act via the same mechanism to inhibit NMDA receptors. Moreover, CO2 inhibits rat NMDA receptors in a manner that is consistent with CO2 MAC-sparing effects in rats.”
NDE’s will unlikely be an area of research that will ever lead to definitive conclusions. Dead men tell no tales and those that survive are unlikely to volunteer their brains for further evaluation, and most patients to survive a cardiac arrest are in no condition to be used in acute clinical studies.
NDE’s appear to be reproducible by medications and are probably the response of the dying brain to an inhospitable metabolic milieu. However, like Houdini, when I die, if I can come back, I will come back and tell you about my dying. In the meantime, if I see the light, I’m not going towards it, no matter how inviting.
Evidence of small-scale magnetic concentrations dragged by vortex motion of solar photospheric plasma
Authors: L. Balmaceda, S. Vargas DomÃnguez, J. Palacios, I. Cabello and V. Domingo.<br />Astronomy and Astrophysics Vol. 513 , page L6<br />Published online: 20/04/2010<br />
Keywords:
convection ; Sun: granulation ; Sun: photosphere ; magnetic fields .
Detection of CO in Triton’s atmosphere and the nature of surface-atmosphere interactions*
Authors: E. Lellouch, C. de Bergh, B. Sicardy, S. Ferron and H.-U. Käufl.<br />Astronomy and Astrophysics Vol. 512 , page L8<br />Published online: 07/04/2010<br />
Keywords:
planets and satellites: atmospheres ; Kuiper belt: general .
Evidence against the young hot-Jupiter around BD?+20?1790***
Authors: P. Figueira, M. Marmier, X. Bonfils, E. di Folco, S. Udry, N. C. Santos, C. Lovis, D. Mégevand, C. H. F. Melo, F. Pepe, D. Queloz, D. Ségransan, A. H. M. J. Triaud and P. Viana Almeida.<br />Astronomy and Astrophysics Vol. 513 , page L8<br />Published online: 23/04/2010<br />
Keywords:
instrumentation: spectrographs ; methods: observational ; techniques: radial velocities ; planetary systems ; stars: individual: BD?+20?1790 ; stars: activity.
Nonaxisymmetric modes of MRI in dissipative Keplerian disks
Authors: L. L. Kitchatinov and G. Rüdiger.<br />Astronomy and Astrophysics Vol. 513 , page L1<br />Published online: 14/04/2010<br />
Keywords:
instabilities ;
magnetohydrodynamics (MHD) ;
magnetic fields ;
accretion, accretion disks
.
H-band thermal emission from the 19-h period planet WASP-19b ***
Authors: D. R. Anderson, M. Gillon, P. F. L. Maxted, T. S. Barman, A. Collier Cameron, C. Hellier, D. Queloz, B. Smalley and A. H. M. J. Triaud.<br />Astronomy and Astrophysics Vol. 513 , page L3<br />Published online: 14/04/2010<br />
Keywords:
planets and satellites: atmospheres ; planetary systems ; stars: individual: WASP-19b ; techniques: photometric.
On mixing at the core-envelope interface during classical nova outbursts
Authors: J. Casanova, J. José, E. GarcÃa-Berro, A. Calder and S. N. Shore.<br />Astronomy and Astrophysics Vol. 513 , page L5<br />Published online: 15/04/2010<br />
Keywords:
novae, cataclysmic variables ; nuclear reactions,
nucleosynthesis, abundances ; convection ;
hydrodynamics ; instabilities ; turbulence .













