Terrace man with neurological medical conditions burned in acid attack – Coast Mountain News

A Terrace man is recovering from chemical burns on his face after being attacked with suspected battery acid and police say that the two culprits remain at large.

Mike Anderson, 51, was walking home after attending the Philanthropy Day event at the Terrace Art Gallery on Sparks Street near Davis Avenue at 8 p.m. on Nov. 15 when he was approached by two men, according to RCMP.

One of them asked Anderson, who is legally blind, for the time. But when Anderson brought his wristwatch up close to his face, the two men sprayed him directly in the face with an acidic substance, which he says he believes might be car battery acid.

I felt my face get wet, and thenI thought they were going to hit me, so I covered myself up. But my eyes were burning, an emotional Anderson told the Terrace Standard on Monday.

Unable to see as the chemical singed his eyes and blistered his face, all he could hear was the uproarious laughter from his attackers. Then he heard a womens voice, asking them to leave.

Soon after, they were gone.

READ MORE: Terrace man recovering from machete attack

I could open one of my eyes, it would sting and kept closing, but I found a puddle so I could wash my face. I tried to use my phone but it was slippery, and it wouldnt unlock, Anderson says. But I was close to home.

In a news release after the incident, RCMP described the two suspects as Indigenous and in their 20s. One had a small beard, the other was wearing a hoodie.

For Anderson, who was diagnosed this year with a complex neurological condition, walking the two blocks from the art gallery to his home is more difficult than for most people.

In August, Anderson suffered two herniated discs in his spine and was flown to Vancouver General Hospital for two weeks for doctors to administer a nerve block, a method of producing anesthesia.

Then a month later in September, he was walking over to a follow-up appointment for his back, he started to feel unwell. Fearing something was wrong, Anderson went to the hospital, where he lost feeling on his left side. He was sent back to VGH right away.

Doctors diagnosed Anderson with conversion disorder, a neurological condition that mimics the symptoms of a stroke. Rather than damage the actual structure of the brain, the disorder impacts a persons ability to do certain things, resulting in conditions including blindness, paralysis and speech problems.

They didnt know why it was happening, he says. Then they eliminated stroke and said it was neurological, but no clots, bleeding or tumours, so thats good news but it will still take time to retrain my brain.

After the attack, the only way Anderson was able to tell how close he was from home was because he could smell the gas coming from a sewer lift station, a concrete sewer basin in the ground, and knew his street was the next one over.

He was able to get home, struggled with the security keypad on his front door, and washed his face in the sink. He called his son on his landline, who then came home and took him to the hospital. Hospital staff could still smell the chemical on his clothes when he was admitted, he says.

It smelled like sulfur, like rotten eggs. RCMP arent sure what it was, but hospital staff think it was maybe car battery acid.

It took six hours to completely flush the substance out of his eyes and lungs, he says. Hospital staff treated the painful blisters on Andersons face with a cream.

Although hes trying to recover, the fear of being attacked while walking around Terrace has stayed with him.

I was scared. I didnt know where they were, and my eyes are bad because of other conditions. I just hoped I hoped I could see again, he says.

Anderson has been to a few eye appointments since the attack, and was told while his eyes are still irritated, no permanent damage was done to his already limited vision.

READ MORE: Terrace ranks in top 10 of magazines Canadas Most Dangerous Places list

After being diagnosed, Andersons family started a GoFundMe page and have since started it back up again after he was attacked. So far, theyve raised $7,010 out of their $8,000 goal to pay for Andersons medical expenses.

The community support to help him and his family has been overwhelming, Anderson says.

Karleen Lemiski contacted the Helping Hands of Terrace about Andersons story, and the organization jumped on board to cover any of his prescription costs, along with a monetary donation. The Terrace Royal Canadian Legion Branch 13 also contacted Anderson to see if they could help with any mobility items, such as a wheelchair, a walker, which can be used to help a person with mobility issues get around, and grab-bars.

The Kimmunity Angels Society was also contacted, and they are looking into whether they can reimburse Andersons September medical flight back from VGH, his new glasses or other medical expenses.

MaXXed Out Cross Trainings Denise Manion has also set up a fundraiser for a heavyweight sled pull competition scheduled for Nov. 28 to Dec. 6 to help the Anderson family.

Police are asking anyone who may have seen anything or know anything about this incident to contact investigators at 250-638-7429.

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Home | Foothills Neurology

Accurate treatment begins with strong diagnostic tools. Theneurologists in Phoenix at Foothills Neurology has both the diagnostics and the specialized treatment necessary to provideexcellent neurology care.

The Foothills Neurology staff consists of a full range of dedicated providers ready to assist your neurological care. Our topneurologist and neurology care providers work as a team to offer patients some of the most comprehensive carein the Phoenix area. As experts in neurological disorders, we treat each individual with compassion and excellent care we would offer our own family. We take time to get to know you as a person, not just a diagnosis. We understandthe anxiety of having a neurological condition can, at times,feel worsethan the condition itself. That is why our dedicated team is here to support you. We take as much time as you need to discuss your condition as well as understand the possibilities and the treatment plan. We are happy to answer your questions and ease your fears by replacing them with genuine support and understanding. Our commitment is to enhance your quality of life. Our patients are in good hands with our strong team of specialists, neurologists and other providers devoted to your health. Schedule an appointment with a Phoenix neurologistat our conveniently located office off theI-10 Maricopa Freeway and East Chandler Boulevard.

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People With Autism Have More Symmetrical Brains. Here’s What That Could Mean – ScienceAlert

In spite of how they appear, the left and right hemispheres of the human brain tend to be far from perfect reflections of each other. Some neurological disorders can affect that imbalance, causing the two halves to appear strikingly alike.

So far, studies on whether autism is among those conditions have been less than convincing. To get a more definitive answer, researchers analysed thousands of brains and showed there is slightly more symmetry for those on the spectrum.

But what does that really mean?

To get this answer, scientistsfrom the Enhancing Neuro-Imaging Genetics through Meta-Analysis consortium collected decades of brain scans from more than 1,700 individuals diagnosed with autism spectrum disorder (ASD) and more than 1,800 with no diagnosis.

The consortium were hardly strangers to analysing huge banks of data, having only recently conducted a similar study on ASD brain anatomy involving more than 3,000 subjects.

The condition covers a spectrum of characteristics that can make life a little more challenging for some, affecting their ability to socialise, communicate, and process stimuli.

With such variation in behaviours, sensations, and impact, tracing the traits making up ASD down to simple neurological differences is no easy task.

Doing so could help make the disorder easier to diagnose and lead to novel therapies, opening the way to providing better methods of assistance for those who need it.

So researchers have been busy looking for clues on all levels of anatomy, from the genes to the gross architecture of our squishy bits.

There have been plenty of investigations into the overall structures of autism-related brains, discovering subtle differences such as the thickness of the cerebral cortex and how key areas link together.

Comparing the ways our brain's mirrored hemispheres reflect each other is a fair way to understand how they develop and communicate.

After all, for most of us, it's differences both between and within the two halves that governs everything from movement to cognitive processes.

Unfortunately, there's still so much we don't know about this contrast between the hemispheres, or 'lateralisation'. So when it comes to learning how lateralisation might be linked with more profound neurological differences, we're still in the dark ages.

There are studies that have found people with ASD have unusually symmetrical brains. There are also studies that found no such thing.

They also tend to be more left handed, and seem less symmetrical in other areas of the brain.

If you're confused about what to make of the mess of conflicting studies, you're not the only one.

"Previous studies have suggested that people with autism spectrum disorder are less likely to have the typical asymmetries for language dominance or hand preference," says geneticist Merel Postema from the Max Planck Institute for Psycholinguistics in the Netherlands.

"However, it has not been clear whether asymmetry of the brain's anatomy is affected in autism, because different studies have reported different findings."

Comparing the thickness of the cortex forming key parts of the brain's outer layer, the researchers found there was comparably less variability across the hemispheres in brains from people with ASD.

These differences didn't vary much depending on sex, medication, or IQ, making it more likely that there was something about autistic brains that accounted for this increased symmetry.

In spite of the significance of the results, it's not enough of a difference to base a diagnosis on.

"The very small average differences in brain asymmetry between affected people and controls mean that changes of brain asymmetry will not be useful in terms of clinical prediction", says the study's leader, Clyde Francks from the Max Planck Institute for Psycholinguistics.

"But the findings might inform our understanding of the neurobiology of autism spectrum disorder".

Some of the differences, for example, appeared in areas containing networks that work harder while we're resting. Just how this might account for some of autism's traits if at all is a task for future studies.

No doubt, there'll be more research on this in the future. Having more information on how our brain works as a whole not only helps us better understand how ASD arises, but how behaviours and functions common to all of us might develop.

This research was published in Nature Communications.

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How to get ready for that all-important visit to a neurologist – GoCogno.com

Get my MCI Treatment Checklist here: https://gocogno.com/mild-cognitive-impairment-treatment/

The Mayo Clinic guidelines on how to get ready to see a primary care doctor or MCI specialist are here: https://www.mayoclinic.org/diseases-conditions/mild-cognitive-impairment/diagnosis-treatment/drc-20354583

Read the Virginia Laken guest blog on why its important to bring someone with you to every appointment: http://virginialaken.com/2019/10/an-absurd-question-written-by-beth/

I know this seems silly now, in the world of instant, on-demand everything, but when I was a kid, they would show The Wizard of Oz on TV once a year.

For us kids, that was a huge deal. We looked forward to it for weeks. And if you missed it, Oh man, you had to wait a whole year for it to come back on TV again.

So really, all Im saying here is that year is a long time to wait for anything, whether its Dorothy and the witch, or whether its something really significant, like say, your next appointment with your neurologist.

For someone with MCI, you can wait months for that first visit with a neurologist. And then have to wait a year to see the neurologist again.

So you really want to be ready for that visit, to get the most out of it. And thats what I want to talk about today.

Hi, Im Tony Dearing, of GoCogno.com, the website for people with mild cognitive impairment.

If you have MCI, or youre dealing with it in your family, I dont have to tell you how important that first or next visit with the neurologist is. People spend months anxiously awaiting it and stressing out about it.

And I want to make sure that you get the most out of it.

So today, I want to share with you three resources to help you do that.

No. 1 is this excellent resource from the Mayo Clinic. It has put together this helpful resource guide that shows you want to expect from a visit to a neurologist and how to get ready for it. You can see some of the examples here.

If you dont already have this tip sheet, you should get it, and familiarize yourself with it. And heres a link to it:https://www.mayoclinic.org/diseases-conditions/mild-cognitive-impairment/diagnosis-treatment/drc-20354583

Tip No. 2 Familiarize yourself with the treatment guidelines for MCI and be prepared to discuss them with your neurologist.

Almost undoubtedly, your neurologist belongs to the American Academy of Neurology. And the academy has an official set of treatment guidelines for mild cognitive impairment.

There was a period of time, way too long, in fact, when these guidelines had become dated. The academy went more than 15 years without updating these guidelines.

Fortunately, thats now been rectified. The academy has actually updated the guidelines twice in the last three years.

So the current guidelines are complete and up to date, and reflect the very best, latest thinking in how MCI should be treated.

I know you want the best possible treatment, and I want to make sure you get it.

So I put together an MCI Treatment Checklist, which you can sign up for and receive. With it, youll also get my weekly brain health email, if youre not already getting it. Both are absolutely free, and here a link to get the checklist:https://gocogno.com/mild-cognitive-impairment-treatment/

Finally, heres tip No. 3. As youre preparing for that visit, make sure that you have someone, ideally a spouse or family member, whos available to go along with you.

This is really important, and to understand why, I encourage you to read a recent post on the blog Virginia Laken, who has MCI and writes about her experiences. This recent piece is a guest post written by Virginias daughter, describing a visit that her mother had with the neurologist and why it was so important that the daughter was there too. You can read that guest post here:http://virginialaken.com/2019/10/an-absurd-question-written-by-beth/

So thats three resources to help you prepare for your next visit to the neurologist. How about you? Do you have any suggestions or tips? Add them to the comments below, or send me an email at tonydearing@gocogno.com.

I hope to hear from you, and I look forward to seeing you again next week. Until then, as always, be kind to your mind.

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Shore Neurology, P.A. | Jersey Shore, NJ, Neurologists

Shore Neurology was honored to have Dr. Ferencz listed as a Top Doctor in Toms River in 2016.

Shore Neurology, P.A. opened in 1986 with the goal of providing progressive neurological care to the Ocean and Monmouth County communitities. Our seven physicians and our nurse practitioner deliver care in our offices in Toms River and Brick, New Jersey.

Our providers are specialists in the treatment of disorders of the nervous system and address diseases of the brain, spinal cord, nerves and muscles. Some of the problems that our neurologists will diagnose and treat are strokes, epilepsy (seizures), headaches and migraines, dementias (Alzheimers disease), multiple sclerosis, Parkinsons disease and various forms of pain. Our neurologists may serve as consultants to other physicians as well as provide long-term care to patients with chronic neurological disorders.

We are a general neurology group practice offering extensive care for a wide range of neurological conditions. We offer several types of neurological subspecialty expertise, including:

Electroencephalograms, electromyograms, nerve conduction velocity studies, physical therapy, carotid ultrasound, and transcranial doppler are all performed in our office.

Our hospital affiliations include Community Medical Center, Ocean Medical Center, HealthSouth Rehabilitation Center and Shore Rehabilitation Institute.

Our physicians and nurse practitioners endeavor to provide you with the best comprehensive neurologic care available.

We hope you find this website helpful in your health and medical care decisions. Please contact us with any questions or for an appointment.

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Shore Neurology, P.A. | Jersey Shore, NJ, Neurologists

Neurosurgery & Neurology Services| UH Ahuja Medical Center …

Expertise and Innovative Care for Neurological Disorders

Headaches, stroke, pain and other conditions related to the nervous system can sometimes evade precise diagnosis and treatment. University Hospitals Neurological Instituteat UH Ahuja Medical Centers Risman Pavilion provides immediate access to an unprecedented level of neurological care for patients in Clevelands eastern suburbs. From standard diagnostic evaluations to advanced neurosurgical procedures, we offer a full range of neurological services and a sophisticated level of care that cannot be found anywhere else on the eastside.

More than just neurology and neurosurgery, our integrated multidisciplinary clinic is staffed by our senior faculty, many of whom are nationally recognized experts in a wide variety of disciplines.

In addition to general neurology, we specialize in:

UH Ahuja Medical Center offers direct access to the same multidisciplinary team of specialists, advanced technology and full range of medical resources available at UH Neurological Institute, based at University Hospitals Cleveland Medical Center. Learn moreabout the services provided at University Hospitals Neurological Institute.

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Neurosurgery & Neurology Services| UH Ahuja Medical Center ...

Available Courses | Office of Sustainability

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Topics include... read more Herbaceous Plants I Undergraduate Landscape Architecture and Horticulture 2221 The identification, culture, and appropriate designs for native and cultivated annuals, perennials, bulbs, and wildflowers; collaboration with nature in designing and maintaining... read more Herbaceous Plants II Undergraduate Landscape Architecture and Horticulture 2222 Topics include: identification, culture, and creation of environmentally appropriate designs for native and cultivated annuals, perennials, herbs, and roses; cost analysis;... read more Landscape Engineering I - III Undergraduate Landscape Architecture and Horticulture 2241, 2242, 3243 Emphasizes the basic concepts, ideas, and techniques that deal with the visual, functional, and ecological aspects of grading and landform manipulation. 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The causes of plant diseases, such as fungi, bacteria, virus, nematodes, plant parasites, as well as environmental stresses,... read more Landscape Restoration Undergraduate Landscape Architecture and Horticulture 3514 Develops an ecologically based understanding of how to establish, restore, and manage meadows, forest, and wetland systems. Emphasizes natural processes and integrating the built... read more Landscape Management Undergraduate Landscape Architecture and Horticulture 3523 Develops an understanding of issues of professional, innovative, and appropriate landscape management. Major focus is given to site analysis, pruning, nutrition, water management... read more Internet and Digital Technologies for Community Engagement Undergraduate Community and Regional Planning 3555 Emerging technologies are directly influencing the planning and management of our urban areas in very profound and pervasive ways. 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Students are required to draw on and implement knowledge about wetland ecosystems to develop a... read more Public Lands Studio Graduate Landscape Architecture and Horticulture 8153 Material presented in LARC 8352: Policies of Public Design Seminar is addressed in this design studio, which focuses on a public project, such as a metropolitan park or regional... read more Environmental Planning Graduate Community and Regional Planning 8213 Environmental issues and concepts faced by planners and the methods used to address them. Applying principles of natural science disciplines to the analysis of man`s physical... read more Sustainability in Suburban Communities Graduate Community and Regional Planning 8255 The physical forms of suburban communities and the social and economic patterns that shape residents' lives make achieving sustainability in suburbia challenging and problematic.... read more Environmental Policy Graduate Community and Regional Planning 8257 This course identifies the complexities associated with environmental politics and management from both national and international perspectives. The first part of the course... read more Aesthetics Ecology Design Seminar Graduate Landscape Architecture and Horticulture 8351 Students learn about the emerging aesthetic associated with ecological design. Form and psychological experience of design are presented through readings and discussion. Students... read more Environmental Infrastructure Planning and Management Graduate Community and Regional Planning 8355 Introduces students to the practice of planning and managing municipal and regional environmental infrastructure programs that typically fall under the realm of a local or county... read more Collaborative Planning Graduate Community and Regional Planning 8476 Students examine the theories, principles, and practices of collaborative planning with a special emphasis on resolving conflicts over land-use planning issues and planning for... read more Transportation Planning Graduate Community and Regional Planning 8655 Presents an overview of the history of transportation in the United States and the fundamentals of present day transportation planning and policies. Explores the influences of... read more Integrated Transportation and Land Use Planning Graduate Community and Regional Planning 8656 Context-sensitive design seeks to blend transportation functions with other human activities and land-use characteristics. Often transportation and land-use decisions have worked... read more Non-motorized Transportation Planning Graduate Community and Regional Planning 8657 Transportation planning in the United States has long focused on improving conditions for motorized travel, primarily by personal cars and light duty trucks. The effects of an... read more NE Woodland Ecosystem Graduate Landscape Architecture and Horticulture 8751 The course presents terrestrial forest ecosystems and the biotic and abiotic factors that affect them. Students learn the components of forest ecosystems, including degradation... read more Wetland Ecology Graduate Landscape Architecture and Horticulture 8752 Refer to department. 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Neurology | ColumbiaDoctors

ColumbiaDoctors neurologists are among the most renowned neurology experts in the world. Neurology and neurosurgery services atNewYork-Presbyterian/Columbia University Medical Center continuously rank among the top programs in the nation, and the Department of Neurology is ranked #2 for NIH-funded research. Patients choose ColumbiaDoctors Neurology, at the famed Neurological Institute of New York or any of our six other convenient locations, for the finest neurological care available.

As one of the largest programs in the country, representing all subspecialties of Neurology, ColumbiaDoctors Neurology offers special expertise in the full range of neurological disorders. Patients who need an initial diagnosis, a second opinion or ongoing care for a wide variety of both chronic and acute neurological disorders will find help and hope with our caring and compassionate providers. Most of our clinicians are also involved in laboratory-based research and clinical trials, offering patients the newest therapeutic options and diagnostic tools.

For your scheduling convenience, ColumbiaDoctors Neurology has implemented a Same Day Neurology Program for new patients! First-time patients who call 646-426-3876 (646-42-NEURO) before 11:00 am are offered a same-day appointment with one of our general neurological specialists from the Division of Multispecialty Neurology. New patients calling after 11:00 am are offered a next day appointment. We offer patients requesting a particular neurologist the soonest available appointment or place them on a waitlist for appointments 10 or more days out.

Our neurological specialties include:

ColumbiaDoctors Neurology Aging and Dementia specialists provide comprehensive, coordinated care for those affected by aging, memory, or related behavioral disorders, including mild cognitive impairment, Alzheimer's disease, Creutzfeldt-Jakob disease, Lewy Body disease, Frontotemporal degeneration, and other less common disorders. Our multidisciplinary team of subspecialty-trained neurologists, neuropsychologists, psychiatrists, genetic counselors, social workers, nurses and other healthcare professionals work together to identify the exact cause of the patient's impairment and advise the patient and his or her family on the best treatment plan for the specific condition.

ColumbiaDoctors Neurology specialists within the Eleanor and Lou Gehrig ALS Center provide comprehensive care to individuals and families with ALS, PLS, and related forms of motor neuron disease (MND). Our ALS physicians and associated healthcare professionals form a multidisciplinary team that offers compassionate care to ALS/MND patients and families and provide the resources necessary to meet the evolving challenges of living with motor neuron disease. Research activities - including clinical trials and genome analysis - are integrated into the ALS Center clinics to give individuals the chance to participate in the fight against ALS/MND. Our personalized approach to patient care values knowledge, understanding, and hope.

The Comprehensive Epilepsy Center team at ColumbiaDoctors Neurology is dedicated to the evaluation and care of patients with epilepsy. We provide state-of-the-art medical and surgical treatment for managing epilepsy in adults, adolescents, and children, with the goal of helping patients gain control of seizures and improve their quality of life. Patients with epilepsy, particularly those with difficult to treat seizures or special issues such as pregnancy, memory, mood, or sleep disorders, will receive cutting-edge care in our center.

ColumbiaDoctors headache and facial pain neurologists have subspecialty training in diagnosing, treating and managing headache and facial pain disorders, in both adults and children. Together, our neurological experts work within an integrated team of pain management specialists, pain psychologists, oral and maxillofacial surgeons, neurosurgeons, and physical medicine specialists to address both common as well as rare intractable headache and facial pain disorders.

ColumbiaDoctors neurologists in the Multiple Sclerosis Clinical Care & Research Center lead a world-class treatment and research facility devoted to exemplary patient care and ground-breaking clinical research for multiple sclerosis and related autoimmune disorders. Our team gives patients comprehensive, coordinated access to a full array of neurological, rehabilitative, and psycho-social services to meet the specific needs of patients with MS.

ColumbiaDoctors Multispecialty Neurology Practice is composed of a coordinated team of neurological specialists with particular expertise in diagnosing and treating both common and complex neurological disorders.

ColumbiaDoctors Neuromuscular Medicine specialists provide comprehensive, multidisciplinary clinical care and advanced electrophysiological diagnostic testing for a broad spectrum of both adult and pediatric neuromuscular disorders. Subspecialty centers and programs within our Division of Neuromuscular Medicine include the Eleanor and Lou Gehrig ALS Center, the Peripheral Neuropathy Center, and the MDA Clinic and H. Houston Merritt Center for Inherited Myopathies and Mitochondrial Diseases.

ColumbiaDoctors Neuro-Oncology specialists provide expert, coordinated care and support to those diagnosed with a brain or central nervous system tumor. Our multidisciplinary team of neuro-oncologists, nurse practitioners and experienced healthcare professionals integrate all aspects of patient care, drawing upon the expertise of highly trained and experienced specialists and other health professionals, to give patients the most current, cutting-edge care and treatment options.

ColumbiaDoctors Neuropsychology Service provides comprehensive neuropsychological testing to diagnose or rule out various conditions in patients and to describe their impact on a person's cognitive functioning. Our tests are tailored to meet the specific needs and concerns of each patient.

Every member of ColumbiaDoctors Neurology movement disorders team is not only specially trained in the care of patients with movement disorders, but also conducts cutting-edge research that advances our knowledge of these complex neurological diseases. Our center is world-renowned for excellence in both clinical care and research related to Parkinson's disease and other movement disorders.

ColumbiaDoctors Neurology has several neurologists who specialize in the diagnosis and treatment of peripheral neuropathies. This group of disorders typically result from damage to the nerves responsible for sending information between the brain, the spinal cord, and the rest of the body. We deliver comprehensive studies, including nerve conduction and advanced treatment options to help a patient best understand his or her diagnosis and treatment options.

ColumbiaDoctors Neurology Sleep Disorder neurologists have expertise in the diagnosis and treatment of sleep disorders, from the common to the complex. We specialize in sleepdisorders (including sleep apnea) in patients with neurologic and/or psychiatric disease. ColumbiaDoctors Neurology offers a range of sleep assessment options, such as testing done during an office visit, overnight studies in our sleep lab, and at-home sleep assessment options.

ColumbiaDoctors Neurology stroke and cerebrovascular disease experts create a continuum of care to minimize damage and give a patient the best chance of survival and quality of life after a stroke. We conduct cutting-edge clinical, epidemiological, and basic science investigations on stroke and cerebrovascular disease making sure our patients receive state-of-the-art care. NewYork-Presbyterian Hospital at Columbia University Medical Center is a major referral center for patients with strokes, guiding the care of patients from other medical centers in the area and in the nation.

ColumbiaDoctors Neurology offers a wide range of advanced diagnostic and treatment services to address each individual patients needs. These include:

ColumbiaDoctors Neurology locations are conveniently located in and around the New York City area:

ColumbiaDoctors Neurology - The Neurological Institute of New York710 West 168th StreetNew York, NY 10032

ColumbiaDoctors Neurology - Midtown51 West 51st Street, Suite 380New York, NY 10019ColumbiaDoctors Child Neurology - Harkness Pavilion180 Fort Washington Avenue, 5th FloorNew York, NY 10032

ColumbiaDoctors Neurology Riverdale3050 Corlear AvenueBronx, NY 10463

ColumbiaDoctors Neurology Westside Pediatrics21 West 86th StreetNew York, NY 10024

ColumbiaDoctors Neurology - Tarrytown155 White Plains RoadTarrytown, NY 10591

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Neurology | ColumbiaDoctors

Interventional Neurology Device Market: Business Opportunities, Current Trends and Industry Analysis by 2037 – Packaging News 24

With having published myriads of reports, Interventional Neurology Device Market Research imparts its stalwartness to clients existing all over the globe. Our dedicated team of experts deliver reports with accurate data extracted from trusted sources. We ride the wave of digitalization facilitate clients with the changing trends in various industries, regions and consumers. As customer satisfaction is our top priority, our analysts are available 24/7 to provide tailored business solutions to the clients.

In this new business intelligence report, Interventional Neurology Device Market Research serves a platter of market forecast, structure, potential, and socioeconomic impacts associated with the global Interventional Neurology Device market. With Porters Five Forces and DROT analyses, the research study incorporates a comprehensive evaluation of the positive and negative factors, as well as the opportunities regarding the Interventional Neurology Device market.

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The Interventional Neurology Device market report has been fragmented into important regions that showcase worthwhile growth to the vendors Region 1 (Country 1, Country 2), region 2 (Country 1, Country 2) and region 3 (Country 1, Country 2). Each geographic segment has been assessed based on supply-demand status, distribution, and pricing. Further, the study provides information about the local distributors with which the market players could create collaborations in a bid to sustain production footprint.

The following manufacturers are covered:MedtronicJohnson and JohnsonTerumo CorporationPenumbra, Inc.Merit Medical Systems, IncW.L. Gore & AssociatesMicroport Scientific CorporationMedikit Co., Ltd.Stryker

Segment by RegionsNorth AmericaEuropeChinaJapanSoutheast AsiaIndia

Segment by TypeEmbolization & coilingNeurothrombectomy Devices

Segment by ApplicationTreatment of Cerebral AneurysmsTreatment of Cerebral VasospasmVertebroplasty

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Patients With Huntington Disease Frequently Report Emotional Issues, Fatigue, and Difficulty Thinking – Neurology Advisor

Emotional issues, fatigue, and difficulties in thinking represent common symptomatic themes in patients with Huntington disease (HD), according to a study published in Neurology.

Patients with manifest HD and prodromal HD (n=20), as well as caregivers of patients with HD (n=20) were included in this international cross-sectional survey study. Researchers conducted qualitative interviews that asked participants about symptoms of HD that had the greatest impact on their lives. Patterns in responses were recorded to identify relevant symptoms across the population. A cross-sectional study was also performed with 156 patients with HD and 233 caregivers. In this study, the researchers examined both the prevalence and importance of 216 symptoms and 15 symptomatic themes in the disease.

Symptomatic themes in this study were defined as concepts that represented a group of like symptoms. In study participants with HD, the most prevalent symptomatic themes included emotional issues (83.0%), fatigue (82.5%), and difficulty thinking (77.0%). As assessed by the average life impact scores, the symptomatic themes associated with the highest relative importance to patients with and caregivers of HD included difficulty thinking (1.91), impaired sleep or daytime sleepiness (1.90), and emotional issues (1.81).

Conversely, the researchers observed a lower prevalence of symptomatic themes in patients who were employed, had High Total Functional Capacity scores, and had prodromal HD. Patients with HD had relatively high rates of emotional issues (71.2%) and fatigue (69.5%), despite these patients having no clinical features of HD.

Patients with manifest HD and caregivers of patients with HD did not participate in the survey as matched pairs, which represents a potential limitation of the study. Another limitation of the study was the self-reported nature of the Total Functional Capacity score and the lack of external validation by a clinician.

The researchers concluded that the knowledge gained of these symptoms is relevant for those in the process of developing experimental therapeutics for those with HD and for those who wish to better explore the symptomatic burden of this population.

Disclosure: Several study authors declared affiliations with the pharmaceutical industry. Please see the original reference for a full list of authors disclosures.

Reference

Glidden AM, Luebbe EA, Elson MJ, et al. Patient-reported impact of symptoms in Huntington disease: PRISM-HD [published online March 19, 2020]. Neurology. doi: 10.1212/WNL.0000000000008906

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Patients With Huntington Disease Frequently Report Emotional Issues, Fatigue, and Difficulty Thinking - Neurology Advisor

Neurology | Summit Medical Group

Neurology is the branch of medicine that involves the nerves and nervous system. Neurologists at Summit Medical Group provide comprehensive care for a wide variety of adult neurological disorders, including diseases of the brain, spinal cord, nerves, and muscles.

Our facility is equipped with state-of-the-art imaging, including magnetic resonance imaging (MRI), carotid ultrasound, computed tomography (CT) scans, and electroencephalograph (EEG) testing. We also can take and submit blood work for laboratory testing, administer infusions and epidural injections, and perform physical therapy.

Common nervous system disorders that a neurologist can diagnose and treat include:

Strokes Damage to part of the brain when its blood supply is suddenly reduced or stopped. A stroke also is called a cerebral vascular accident or CVA. The part of the brain deprived of blood dies and can no longer function properly.

Epilepsy (seizures) A condition caused by brief, strong surges of electricity that affect all or part of the brain. Seizures can impact physical and mental health.

Headaches Pain in the upper neck and head that varies in severity and frequency. Headaches occur from a wide range of causes.

Dementias such as Alzheimers disease A gradual loss of mental functions such as the ability to think, remember, reason, and plan.

Multiple sclerosis A disease of the central nervous system (the brain and spinal cord) that causes loss of coordination and muscle control.

Parkinsons disease A disease that occurs when some of the nerve centers in the brain lose the ability to control muscle movement. The condition can result in rigid muscles, tremors, and difficulty with walking and swallowing.

Various forms of pain Neuropathic pain can result from injury or damage to the nerves.

Neurologists at Summit Medical Group are highly qualified and have extensive training and clinical experience. In addition, they have taught courses in some of the nations top academic centers.

Summit Medical Group neurologists are experts in:

See experts at our Go Red Day: Heart Disease and Stroke Awareness Expo discuss important ways you can protect your health.

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Neurology | Summit Medical Group

Flea and tick medication companies respond to 5 On Your Side – WRAL.com

Elanco Animal Health (Credelio)

"Weve worked diligently to communicate the class change to veterinarians and also feature specific language on seizures in our Credelio advertisements. Also, FDA did not determine the final language re: seizure risk until after Credelio was approved. So, Elanco included the following language in the Credelio label with approval from the FDA: 'Use with caution in dogs with a history of seizures' at time of product approval."

"Nothing is more important to Merck Animal Health than the safety and efficacy of our products and the well-being of animals. We continue to encourage all pet owners to speak to their veterinarian before making any decisions about flea and tick control products. Parasites like fleas and ticks are not only a nuisance for pets and their owners, but if left untreated they can transmit serious diseases to pets.

It is important to note that the FDA updated the labeling for the entire class of isoxazoline drugs in September of 2018.

Pet-owner product materials, including advertising, displays and brochures have been updated with the new safety information.

Merck Animal Health is confident in the safety and efficacy of our products such as Bravecto and follow all legal and regulatory requirements. The safety and efficacy of Bravecto has been established through comprehensive research in more than 170 clinical research studies. In addition, more than 125 million doses of Bravecto have been distributed in 85 countries. The overall worldwide reporting rate for adverse events for our products containing isoxazoline remains classified as rare."

"In September 2018, the U.S. Food and Drug Administrations (FDA) Center for Veterinary Medicine (CVM) released a public communication to pet owners and veterinarians regarding the use of flea-and-tick-control products within the isoxazoline class of drugs. In this announcement, the FDA reported receiving reports of neurological signs in some dogs and cats following the use of products within the class. CVM issues these communications to veterinarians and pet owners to aid in making decisions about animal health products.

NexGard is an oral, beef-flavored soft chew that is administered monthly to dogs. It contains the active substance afoxolaner, a compound in the isoxazoline class, for the treatment and prevention of flea infestations and the treatment and control of ticks in dogs for one month. NexGard is approved by regulatory authorities for use in more than 100 countries, with more than 330 million doses sold worldwide. While the FDA notes that reports involving neurological signs have been reported for all isoxazoline products, they remain very rarely reported with NexGard (very rare defined as The most commonly reported adverse events in the US are vomiting, pruritus, lethargy, diarrhea, and anorexia. The NexGard label was updated with the information that the FDA described in their announcement.

The efficacy and safety of our products are paramount, and we believe that it is important for veterinarians and pet owners to be aware of any potential risks associated with products used in pets. As with any veterinary product, we recommend that pet owners discuss with their veterinarian before using a product."

"Zoetis colleagues, many of us pet owners, care about the well-being of pets, and we are committed to providing safe and effective products to veterinarians, pet owners and the animals in their care. We all sympathize with the frustration and concerns of pet owners when their pets are sick.

Our product Simparica (sarolaner) Chewables is one of four tick and flea medications for dogs in the isoxazoline class currently on the market. The labeling for Simparica is approved by the FDA. The product label and all of our promotional materials have always included information about neurologic signs such as tremors, unsteadiness, and/or seizures that have been associated with use of medicines in the isoxazoline class in some dogs.

Our product labeling for Simparica was approved by the FDA and updated in June 2019 to reflect their comments on neurologic events. Here is the website with prescribing and safety information for Simparica. You can click through from here for more detailed information that is shared in the packaging as well. https://www.zoetisus.com/products/dogs/simparica/prescribing-information.aspx

We are confident that Simparica, which has been sold in the U.S. for 4 years, remains an effective and safe tick and flea option for dogs. The overall global reporting rate for any clinical sign reported for Simparica (including vomiting, lethargy, diarrhea or any neurologic sign), is classified as very rare as defined by international regulatory authorities as less than 1 report per 10,000 doses administered (This rate was calculated based on all reports regardless of any causal relationship to the product). Simparicas adverse event profile continues to be predictable and consistent with pre-approval studies and looks similar to other isoxazoline products on the market.

We focus on ensuring veterinarians have the proper education, prescribing and safety information to share with pet owners, so that they can best advise each pet owner which products are the best choice for their individual pet and best suited to each pets medical needs. We also encourage pet owners to have regular conversations with veterinarians about their pets health.

Unfortunately, all medicines come with some potential risks and side effects and that is why their use should always be taken in consultation with a veterinarian. For the vast majority of pets, tick and flea medicines are safe, effective and help greatly reduce health risks that can come from parasites, such as Lyme disease, anemia and other infectious diseases. These are serious health concerns for all dogs and regular use of tick and flea medicines is recommended by veterinarians throughout the United States.

Revolution Plus for cats is also an isoxazoline product (sarolaner) and was approved in the U.S. in 2018 and launched there in 2019. Simparica was approved in launched in the U.S. in 2016."

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Flea and tick medication companies respond to 5 On Your Side - WRAL.com

This Week: First Possible Community Spread of COVID-19 in the U.S.; Stranger Things Actor Raising Public Awareness; and more – DocWire News

In this weeks DocWire Homepage news: The CDC confirms the first possible case of COVID-19 community spread in America; mistreatment in medical school is more common among women, minority, and LGB students; brain iron may predict the onset of dementia in patients with Parkinsons disease; and find out what rare condition a Stranger Things actor has helped raise public awareness on.

This week, the Centers for Disease Control and Prevention (CDC) confirmed an infection of theWuhan coronavirus, COVID-19, in California in a person who reportedly did not have any relevant travel history to an area affected by the outbreak, nor did they have exposure to a known patient with the virus. This development comes after the CDC warned Americans on Tuesday to prepare for an imminent COVID-19 spread in the U.S., saying its not a matter of if, but when.The CDC noted that the federal government is currently working closely with state, tribal, and territorial partners to mitigate the spread of COVID-19, which hasnow killedat least 2,800 people worldwide.

CDC Confirms First Possible Instance of COVID-19 Community Spread in U.S.

The findings of a new study suggest that female, underrepresented minority (URM), Asian, multiracial, and lesbian, gay, or bisexual (LGB) students seem to bear a disproportionate burden of the mistreatment inmedical school. Thestudy appearedinJAMA Internal Medicine. In this cohort study, they analyzed data from the 2016 and 2017 Association of American Medical Colleges Questionnaire, which annually surveys graduating students from all 140 accredited allopathic medical schools in the US. The results showed that mistreatment was more commonly reported by women, minority, and LGB students compared to their male, white, and heterosexual counterparts.

Study: Mistreatment in Medical School is More Prevalent Among Female, Minority, and LGB Students

Measures of iron in the brain might eventually predict dementia inpatients withParkinsons disease (PD), according to the findings of astudy publishedin theJournal of Neurology, Neurosurgery, and Psychiatry. In this study, the researchers analyzed 100 patients with early-to-mid stage PD along with 37 age-matched controls using an algorithm for assessing cognitive decline risk in PD. Subsequent to analysis, the results showed that iron accumulation in the hippocampus and thalamus brain regions are associated with poor memory and thinking scores in patients with PD. First author, PhD student George Thomas (UCL Queen Square Institute of Neurology), added that: Its really promising to see measures like this which can potentially track the varying progression of Parkinsons disease, as it could help clinicians devise better treatment plans for people based on how their condition manifests.

Measures of Brain Iron May Predict the Onset of Dementia in Patients with Parkinsons Disease

TheNetflixoriginal series,Stranger Things,has helped generate increased public awareness of the rare disorder cleidocranial dysplasia (CCD) thanks to actor Gaten Matarazzo III, according to the findings of aresearch letterpublished in JAMA Otolaryngology Head & Neck Surgery. Since the introduction of CCD onStranger Things,Matarazzo helped establish the foundation CCD Smiles to promote global awareness, provide dental care assistance, and support research.Through their expansive reach to the public and media connections, celebrities such as Matarazzo may serve as positive agents to raise awareness and educate the general public, the research authors wrote.

Stranger Things Actor Gaten Matarazzo III Has Increased Public Awareness of Cleidocranial Dysplasia

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This Week: First Possible Community Spread of COVID-19 in the U.S.; Stranger Things Actor Raising Public Awareness; and more - DocWire News

Music therapy sessions available to residents living with neurological conditions in Twickenham – Richmond and Twickenham Times

Residents living with neurological conditions in Twickenham can now access Integrated Neurological Services (INS) that have been provided by the Otakar Kraus Music Trust (OKMT).

The INS service - which is also supported by the People's Postcode Lottery, has provided music therapy to people living in the borough since 1991, however its Twickenham service launched on February 3.

Each music therapy session is aimed at improving the physical and mental well-being of children and adults living with learning, physical neurological or emotional difficulties.

Clare Lawrence, Director of OKMT said, We are very grateful to players of Peoples Postcode Lottery and Postcode Community Trust for the Grant which will enable us to provide a safe therapeutic space for clients at INS, where we can use music therapy to help them explore emotional expression, engage in social interaction and adjust to their disability.

Neurological music therapy is an evidence-based treatment which can help those with neurological conditions to have improved cognition, communication and movement.

A qualified music therapist will provide small group music therapy sessions for over 30 people with neurological conditions such as stroke, Parkinsons and MS, many of whom have mobility, cognitive and communication issues and may suffer isolation and depression.

Each student learns breathing and signing techniques that are aimed at improving the flow of speech as some residents often sing words they cannot say.

Creating songs about every day activities can also help improve a student's cognition and memory.

Students are also encouraged work on their movement by playing an instrument or walking to a beat which strengthens any weakened muscles.

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Music therapy sessions available to residents living with neurological conditions in Twickenham - Richmond and Twickenham Times

Mexico Neurology Procedures Outlook to 2025 – Epidemiology Based models are Used to Estimate & Forecast the Procedure Volumes -…

The "Mexico Neurology Procedures Outlook to 2025 - Hydrocephalus Shunting Procedures, Neurovascular Thrombectomy Procedures, ICP Procedures and Others." report has been added to ResearchAndMarkets.com's offering.

Summary

The publisher's new report, Mexico Neurology Procedures Outlook to 2025, provides key procedures data on the Mexico Neurology Procedures. The report provides procedure volumes within market segments - Hydrocephalus Shunting Procedures, Neurovascular Thrombectomy Procedures, Neurovascular Embolization Procedures, Neurovascular Coiling Assist Procedures, Neurovascular Accessory Procedures, Intracranial Stenting Procedures, ICP Procedures, Dura Substitute Procedures, Neuromodulation Procedures and Minimally Invasive Neurosurgery Procedures.

The data in the report is derived from dynamic market forecast models. The objective is to provide information that represents the most up-to-date data of the industry possible.

The epidemiology-based forecasting model makes use of epidemiology data gathered from research publications and primary interviews with physicians to establish the target patient population and treatment flow patterns for individual diseases and therapies. Using prevalence and incidence data and diagnosed and treated population, the epidemiology-based forecasting model arrives at the final numbers.

Extensive interviews are conducted with key opinion leaders (KOLs), physicians and industry experts to validate the procedure volumes.

Scope

Mexico Neurology Procedures volumes by segments Hydrocephalus Shunting Procedures, Neurovascular Thrombectomy Procedures, Neurovascular Embolization Procedures, Neurovascular Coiling Assist Procedures, Neurovascular Accessory Procedures, Intracranial Stenting Procedures, ICP Procedures, Dura Substitute Procedures, Neuromodulation Procedures and Minimally Invasive Neurosurgery Procedures.

Projections for each of the market segments. Data is provided from 2015 to 2025.

Develop business and investment strategies by identifying the key market segments expected to register strong growth in the near future.

Develop market-entry and market expansion strategies.

Reasons to buy

Story continues

Develop business and investment strategies by identifying the key market segment expected to register strong growth in the near future.

Develop market-entry and market expansion strategies.

Key Topics Covered:

1 Table of Contents

1.1 List of Tables

1.2 List of Figures

2 Introduction

2.1 What Is This Report About?

2.2 Neurology Procedures Segmentation

2.3 Definitions of Procedures Covered in the Report

3 Neurology Procedures, Mexico

3.1 Neurology Procedures, Mexico, 2015-2025

3.2 Neurology Procedures, Mexico, 2015-2025

4 Dura Substitute Procedures, Mexico

4.1 Dura Substitute Procedures, Mexico, 2015-2025

5 Hydrocephalus Shunting Procedures, Mexico

5.1 Hydrocephalus Shunting Procedures, Mexico, 2015-2025

5.1.1 Revision Hydrocephalus Shunts Procedures, Mexico, 2015-2025

6 ICP Procedures, Mexico

6.1 ICP Procedures, Mexico, 2015-2025

7 Intracranial Stenting Procedures, Mexico

7.1 Intracranial Stenting Procedures, Mexico, 2015-2025

8 Minimally Invasive Neurosurgery Procedures, Mexico

8.1 Minimally Invasive Neurosurgery Procedures, Mexico, 2015-2025

8.1.1 Minimally Invasive Neurosurgical Devices Procedures, Mexico, 2015-2025

9 Neuromodulation Procedures, Mexico

9.1 Neuromodulation Procedures, Mexico, 2015-2025

10 Neurovascular Accessory Procedures, Mexico

10.1 Neurovascular Accessory Procedures, Mexico, 2015-2025

11 Neurovascular Coiling Assist Procedures, Mexico

11.1 Neurovascular Coiling Assist Procedures, Mexico, 2015-2025

12 Neurovascular Embolization Procedures, Mexico

12.1 Neurovascular Embolization Procedures, Mexico, 2015-2025

12.1.1 Flow Diversion Stent Procedures, Mexico, 2015-2025

13 Neurovascular Thrombectomy Procedures, Mexico

13.1 Neurovascular Thrombectomy Procedures, Mexico, 2015-2025

14 Appendix

For more information about this report visit https://www.researchandmarkets.com/r/3rr42v

View source version on businesswire.com: https://www.businesswire.com/news/home/20200214005336/en/

Contacts

ResearchAndMarkets.comLaura Wood, Senior Press Managerpress@researchandmarkets.com For E.S.T. Office Hours Call 1-917-300-0470For U.S./CAN Toll Free Call 1-800-526-8630For GMT Office Hours Call +353-1-416-8900

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Mexico Neurology Procedures Outlook to 2025 - Epidemiology Based models are Used to Estimate & Forecast the Procedure Volumes -...

Bartonella infection everywhere, but we don’t know about it – Charlotte Post

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A North Carolina State University professor says Bartonella infection is one of the most important untold medical stories.

Ed Breitschwerdt, a professor of veterinary sciences at North Carolina State University, keeps waiting for the tipping point. For the last 30 years, Breitschwerdt has been studying Bartonella, a genus of bacteria found in animals, ticks and humans.

Its frustrating, said Breitschwerdt. I believed we would hit a tipping point two years ago with this.

Laura Hoppers tipping point came in 2006, when she was 15 years old. The Raleigh teen lost her peripheral vision. She next began to suffer bouts of joint and muscle pain and numbness in her hands. Then came the headaches, memory loss and hallucinations.

As a mother, its so hard to watch your child have all these symptoms, said Maria Hopper. It was a couple years of going to all kinds of doctors.

But no neurologist, rheumatologist or psychiatrist could explain all of Lauras symptoms. And it wasnt until 2008, when the Hoppers read a news article about Bartonella and Breitschwerdts work, that a lightbulb went off in their heads.

Though people have known of cat scratch disease the most public of the human diseases caused by Bartonella infection for more than 100 years, Breitschwerdt said hes convinced that Bartonella is the stealth cause of many neurological, inflammatory and chronic diseases in humans.

And, unlike Lyme disease, another tick-borne illness that can cause an array of distressing symptoms, Bartonella is right in the backyard of most North Carolinians.

Its a medically important bacteria in animals and humans in the state. If you took every stray cat along the coast of North Carolina, three quarters of them would have Bartonella, said Breitschwerdt. Thats because the bacteria is commonly transmitted to animals by fleas.

He said that, historically, vets have considered common cat flea a nuisance but have under-appreciated it as a disease vector. For several years, Breitschwerdt has seen all sorts of animals and mites, ticks, fleas and even spiders test positive for Bartonella.

Animals are the primary reservoir for the Bartonella species, he said.

Breitschwerdt has worked with the One Health Commission, a collective that looks at the links between environmental, human and animal health. Though his professional and personal life has been guided by his care for animals, his most recent work is geared towards detecting and treating Bartonella infection in humans.

The recovery processThe Hoppers contacted Breitschwerdt at a fortunate time: He was developing new human diagnostic method for Bartonella. Laura tested positive, and after three courses of months-long antibiotic treatments, her symptoms have all but disappeared.

By the end of the first cycle [of antibiotics], the feeling in her hands came back, said Maria. By the end of the second cycle, hallucinations stopped. Though Laura still suffers some muscle pain, she considers herself 80 to 90 percent healed.

If the bacteria is positively detected, treating Bartonella infection is a daunting task for even otherwise healthy patients

You cannot float humans or horses in enough Doxycycline to kill this bacteria, said Breitschwerdt. Treatment, such as Lauras, requires weeks of multi-antibiotic therapies.

Laura was also lucky in that she tested positive for Bartonella immediately.

A patient infected can have a negative test on a Monday and positive test by Wednesday.

People are tested several times, but Bartonella can hide in the body, Breitschwerdt said.

Thats because an animal scratch or bug bite (or a vets needle stick) results in Bartonella infection in red blood cells and endothelial cells, which line blood vessels. The bacteria can hide out for many infectious cycles, causing symptoms and eventually affecting every organ system in the body.

Most people can clear Bartonella from their bloodstreams effectively. But among the subset of people who cant eliminate the bacteria, help in mainstream medicine will be difficult to come by.

I often talk with veterinarians who have these vague complaints who say theyve been sick for weeks or months, said Breitschwerdt.

Many of the vets receive diagnoses of Lyme disease, chronic fatigue, rheumatoid arthritis, or are sent to a psychiatrist and told their symptoms are untreated depression. But Breitschwerdt cautions them to get tested for Bartonella.

Breitschwerdt has ventured into industry with Galaxy Diagnostics, a company he founded to offer Bartonella testing kits to doctors. The company launched into human testing two years ago, and has received orders from 300 doctors across the country.

At this stage, said Amanda Elam, Galaxys president, the companys goal is to educate people about Bartonella.

Were dong continuing medical education courses, working with people in public health and doing education with veterinarians, she said. Id really like the medical community to keep an open mind about this.

While Breitschwerdt waits for the public tipping point for Bartonella, he said he too is focused on disease education.

It takes 10 years before something added to the medical textbooks gets widely spread in practice, he said. Were working on changing those textbooks.

This article first appeared on North Carolina Health News and is republished here under a Creative Commons license.

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Bartonella infection everywhere, but we don't know about it - Charlotte Post

Does the Interplay of Callous-Unemotional Traits and Moral Disengageme | AHMT – Dove Medical Press

Marinella Paciello,1 Giulia Ballarotto,2 Luca Cerniglia,1 Pietro Muratori3

1Faculty of Psychology, Uninettuno Telematic International University, Rome, Italy; 2Department of Dynamic and Clinical Psychology, Sapienza University, Rome, Italy; 3IRCCS Fondazione Stella Maris, Scientific, Institute of Child Neurology and Psychiatry, Calambrone, Pisa, Italy

Correspondence: Marinella PacielloFaculty of Psychology, Uninettuno Telematic International University, Corso Vittorio Emanule II, Rome 39 00186, ItalyEmail m.paciello@uninettunouniversity.net

Abstract: Disruptive behavior could represent an (un)moral behavioral component of multi-dimensional construct of morality that includes affective and cognitive aspects. Thus, it is pivotal to investigate their interplay between affective and cognitive processes the better to understand how to intervene to contrast disruptive behavior and its antisocial outcomes. The present review has examined the relationship between affective and cognitive processes implied in moral functioning by focusing on callous-unemotional traits (CU) and moral disengagement. Starting from 1005 records identified by PsycINFO, Pubmed, and Pubpsych, only 13 studies have been selected. These studies show different theoretical approaches and methodologies and put in evidence the nuances of possible interactions of CU and moral disengagement during adolescence based on different research field. Overall, most of the scholars seem to conclude that different interplay can be plausible, suggesting that it is likely that during the adolescence the influence of moral disengagement and CU is reciprocal and longitudinal. Specifically, in adolescents with Disruptive Behavior DisordersCU and moral disengagement can move together in organizing and becoming chronic of antisocial affective-cognitive system, and in particular moral disengagement may give a free way to engage in disruptive behavior.

Keywords: disruptive behavior, callous-unemotional traits, moral disengagement, adolescence, morality

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Does the Interplay of Callous-Unemotional Traits and Moral Disengageme | AHMT - Dove Medical Press

Global Drug Discovery Services Market is Projected to Reach USD 19.1 Billion By 2025 at a CAGR of 12.1% from 2020 to 2025 – ResearchAndMarkets.com -…

DUBLIN--(BUSINESS WIRE)--The "Drug Discovery Services Market by Process (Target Selection, Validation, Lead Optimization), Type (Medicinal Chemistry, DMPK), Drug Type (Biologics, Small Molecules), Therapeutic (Oncology, Neurology), Company (Tier 1, 2, 3) - Global Forecast to 2025" report has been added to ResearchAndMarkets.com's offering.

Drug discovery services market to register a CAGR of 12.1% from 2020 to 2025.

The growth of the industry is driven primarily by factors such as growing R&D expenditure in the pharmaceutical & biopharmaceutical industry, increasing demand for outsourcing analytical testing and clinical trial services, initiatives for research on rare diseases and orphan drugs, and focus on drug discovery. Growth in the biologics market and patent expiries will further provide opportunities in the drug discovery services industry. Developing economies are expected to offer a wide range of growth opportunities for players in the market.

The Hit-to-Lead process segment is anticipated to grow at the fastest growth rate during the forecast period.

Based on the process, the drug discovery services market is segmented into target selection, target validation, hit-to-lead identification, lead optimization, and candidate validation. Hit-to-lead identification process is anticipated to be the fastest-growing segment due to the high outsourcing of these services to CROs by the pharmaceutical companies and the emerging advanced technologies for high-throughput screening (HTS) and H2L as well as reductions in development time.

Medicinal Chemistry segment is estimated to account for the largest share of the drug discovery services market in 2020.

Based on type, the drug discovery services market is segmented into medicinal chemistry services, biology services, and drug metabolism and pharmacokinetics (DMPK). The medicinal chemistry services segment is estimated to account for the largest share of the drug discovery services market due to the widespread application of medicinal chemistry in various phases of preclinical drug discovery to deliver robust candidates.

Oncology segment is anticipated to grow at the fastest growth rate during the forecast period.

Based on the therapeutic area, the drug discovery services market is segmented into oncology, cardiovascular diseases, neurology, infectious and immune system diseases, digestive system diseases, and other therapeutic areas. Of all these therapeutic segments, oncology will grow at the fastest CAGR in the drug discovery services market in 2019. The high growth of the oncology segment can be attributed to factors such as the increasing number of patients who have cancer, the subsequent increase in the demand for cancer therapies and the growing R&D expenditure by pharmaceutical companies in this therapeutic area.

North America is expected to dominate the drug discovery services market in 2020.

North America, which includes the US and Canada, is estimated to account for the largest share of the drug discovery services market. The large share of this region can primarily be attributed to the presence of well-established CROs; rising R&D expenditure by pharmaceutical & biopharmaceutical companies and the availability of latest techniques, instruments, and facilities for drug discovery research are driving the growth of this region.

Reasons to Buy the Report:

Key Topics Covered:

1 Introduction

1.1 Objectives of the Study

1.2 Market Definition

1.3 Market Scope

1.4 Currency

1.5 Limitations

1.6 Stakeholders

2 Research Methodology

2.1 Research Data

2.2 Market Size Estimation

2.3 Market Breakdown and Data Triangulation

2.4 Assumptions for the Study

3 Executive Summary

4 Premium Insights

4.1 Drug Discovery Services Market Overview

4.2 North America: Market, By Drug Type & Country (2020)

4.3 Market: Geographic Growth Opportunities

5 Market Overview

5.1 Introduction

5.2 Market Dynamics

5.2.1 Drivers

5.2.2 Restraints

5.2.3 Opportunities

5.2.4 Trends

6 Drug Discovery Services Market, By Process

6.1 Introduction

6.2 Target Selection

6.3 Target Validation

6.4 Hit-To-Lead Identification

6.5 Lead Optimization

6.6 Candidate Validation

7 Drug Discovery Services Market, By Type

7.1 Introduction

7.2 Medicinal Chemistry Services

7.3 Biology Services

7.4 Drug Metabolism & Pharmacokinetics

8 Drug Discovery Services Market, By Drug Type

8.1 Introduction

8.2 Small-Molecule Drugs

8.3 Biologic Drugs

9 Drug Discovery Services Market, By Therapeutic Area

9.1 Introduction

9.2 Oncology

9.3 Neurology

9.4 Infectious and Immune System Diseases

9.5 Digestive System Diseases

9.6 Cardiovascular Diseases

9.7 Other Therapeutic Areas

10 Drug Discovery Services Market, By Company Type

10.1 Introduction

10.2 Tier 1 Pharmaceutical Companies

10.3 Tier 2 Pharmaceutical Companies

10.4 Tier 3 Pharmaceutical Companies

11 Drug Discovery Services Market, By Region

11.1 Introduction

11.2 North America

11.3 Europe

11.4 Asia Pacific

11.5 Rest of the World

12 Competitive Landscape

12.1 Overview

12.2 Market Share Analysis

12.3 Competitive Scenario

12.4 Competitive Leadership Mapping

13 Company Profiles

13.1 Laboratory Corporation of America Holdings

13.2 Eurofins Scientific Se

13.3 Charles River Laboratories International

13.4 Evotec SE

13.5 Thermo Fisher Scientific

13.6 Albany Molecular Research, Inc.

13.7 Syngene International Limited

13.8 Jubilant Lifesciences

13.9 Genscript Biotech Corporation

13.10 Piramal Enterprises Limited

13.11 Selvita S.A.

13.12 Aurigene Discovery Technologies

13.13 Domainex Ltd.

13.14 WuXi AppTec

13.15 Chempartner Co., Ltd.

13.16 Frontage Holdings

13.17 Pharmaceutical Product Development, LLC

13.18 Shanghai Medicilon, Inc.

13.19 TCG Lifesciences Pvt. Limited

13.20 Viva Biotech (Shanghai) Ltd.

For more information about this report visit https://www.researchandmarkets.com/r/i0k3fl

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Global Drug Discovery Services Market is Projected to Reach USD 19.1 Billion By 2025 at a CAGR of 12.1% from 2020 to 2025 - ResearchAndMarkets.com -...

Alexion’s neuro bet, Rubius’ trial troubles and biotech’s gene therapy milestones – BioPharma Dive

SAN FRANCISCO Pharmaceutical companies and their investors have grown accustomed to big news kicking off the year, specifically multibillion-dollar deals.

The last three J.P. Morgan Healthcare Conferences, considered a sort of Opening Day for the industry, were hallmarked by the acquisitions of Ariad Pharmaceuticals, Impact Biomedicines and Loxo Oncology. (And that's not including Bristol-Myers Squibb's $74 billion deal for Celgene the week before the meeting last year.)

In fact, Eli Lilly pressed Loxo for a quick buyout to have something flashy to announce at last year's conference. Such enthusiasm was noticeably absent this time around, though, resulting in a quieter first day than biotech shareholders had hoped for.

The Nasdaq Biotechnology Index fell almost 2%, with Sage Therapeutics, Clovis Oncology and other potential takeover targets trading down by market's close. Brad Loncar, a founder of biotech exchange-traded funds, noted on Twitter how even shares of MorphoSys fell despite the German drugmaker having the most positive news of the day.

While major M&A announcements seem unlikely for the rest of the week, industry experts still expect the challenges facing bigger companies will result in a healthy number of deals in 2020. In the meantime, biotechs will be busy trying to deliver on their development plans some of which were provided in more detail during Monday's presentations.

Connecticut-based Alexion Pharmaceuticals is best known for its high-priced rare disease drugs Soliris and Ultomiris. On Monday, the company gave an early look at full-year financials, reporting a top line revenue increase of more than 20% between 2018 and 2019. That growth correlates to, at the very least, roughly $4.96 billion in annual revenue, which would be slightly higher than the average analyst estimate.

For Stifel's Paul Matteis, more surprising than the revenue beat was Alexion's plan to treat four times as many U.S. neurology patients with Soliris and Ultomiris by 2025. If successful, the plan would create a "substantial upside" to revenue estimates, according to the analyst.

"This of course raises a number of natural questions," Matteis wrote in a note to investors, "such as where will this growth come from, and what does it assume (if anything) for additional neuro indications where Soliris/Ultomiris isn't derisked."

Shareholders, however, responded positively to the updates, sending Alexion shares up 4%.

Soliris is approved to treat several diseases, including a chronic neuromuscular illness known as gMG and a type of central nervous system inflammation abbreviated as NMOSD. Alexion says that, in less than two years time, these neurology indications have become its largest franchise by patient volume. By the end of 2019, almost 1,900 U.S. neurology patients were taking Soliris.

Ultomiris, a follow-on to Soliris, is under investigation as a treatment for gMG and NMOSD across a couple of late-stage studies. And on Tuesday, Alexion announced it will soon begin a Phase 3 study of the drug in ALS, with plans to enroll 350 adults in a 50-week trial.

Selling new paths to growth is particularly important for Alexion now, as the company has come under pressure from activist investor Elliott Advisors to seek a sale.

BioMarin could bring the first hemophilia gene therapy to market later this year. While waiting for regulators to confirm its approval application is under review, the California biotech announced Monday it has more than doubled capacity at a gene therapy plant. Altogether, the facility can make up to 10,000 doses each year of either the hemophilia treatment or a separate BioMarin gene therapy that's about to begin human testing.

That capacity level, according to executives, would allow the company to treat all U.S. hemophilia A patients in roughly two year's time. The update increases the competitive pressure on drugmakers with marketed products, such as Takeda and Novo Nordisk, as well as those working on rival hemophilia gene therapies. Swiss pharma giant Roche falls into both buckets, and could lose out on many patients because of BioMarin, according to a recent doctor survey from Citi Research.

Sarepta Therapeutics also had a manufacturing update, announcing that production for its experimental micro-dystrophin gene therapy is now large enough to be considered commercially viable.

RBC Capital Markets analyst Brian Abrahams called this a "critical manufacturing milestone" for Sarepta, one that shores up the timeline for a pivotal study scheduled to start sometime in the middle of the year.

Despite launching one of the industry's largest initial public offerings in 2018, Rubius Therapeutics has struggled out of the gate in getting its first clinical data. While its ambitions are large, the Flagship Pioneering-backed biotech failed to meet expectations it set for delivering early Phase 1 data from its lead asset, a PKU drug, by the end of 2019.

"We understand what we didn't do right in 2019, and we are doing it differently in 2020," CEO Pablo Cagnoni told a half-filled breakout room at the JPM conference. "We will deliver in 2020."

While Cagnoni and other executives emphasized cancer therapies set to enter clinical testing in 2020 and speedy progress on its own manufacturing plant, the biotech also admitted it still has not dosed a single PKU patient to date, calling into question the company's ability to execute.

Pressuring Rubius further is BioMarin's announcement that it will develop a PKU gene therapy, with plans to dose its first patient this quarter. BioMarin already sells two PKU drugs and could be a formidable competitor.

Shares in Rubius ticked down by about 5% Monday and have shed two-thirds of their value since the company went public.

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Alexion's neuro bet, Rubius' trial troubles and biotech's gene therapy milestones - BioPharma Dive

Migraines at the forefront of Cairo conference – Health – Life & Style – Ahram Online

The phrase crippling headache is as accurate as it gets for millions around the globe -- a bad headache can get in the way of everything.

Last Thursday, the Headache Chapter of the Egyptian Society of Neurology, Psychiatry and Neurosurgery (ESNPN) and pharmaceutical firm Novartis held a conference in Cairo to discuss migraines, including causes and treatments.

The conference organisers also launched the hashtag #BalashSuda3 to raise public awareness of different kinds of headaches, their causes and their treatment options, with a special focus on migraines.

Migraines decoded

Dr. Mohamed Osama Abdelghany, the head of the Headache Chapter, explained that migraines are a neurological disease in which genetics and environmental factors appear to play a role, although the exact causes are still shrouded in mystery.

"Migraine in Arabic historically had a very significant name el-shakeeka -- meaning 'what splits the head into two'. With such accuracy, our ancestors explained its effect, he said.

"It is typically a severe throbbing recurring pain, usually on one side of the head, and is often accompanied by debilitating symptoms such as nausea, vomiting, dizziness, extreme sensitivity to sound, light, touch and smell.

A common disease

Understanding the magnitude of the problem requires a look at the data.

Migraine affects more than 10 percent of the global population and is two to three times more common in women than in men. Research suggests that 3,000 migraine attacks occur every day for each million of the general population. The disease is most common between the ages of 25 and 55, said Abdelghany.

Comprehensive data is not available for the whole of Egypt, so experts tend to rely on two key studies conducted in the governorates of Assiut and Fayoum.

"A study on primary headache disorders in Fayoum on 2,600 patients and in Assiut on 5,000 patients revealed that more than 60 percent of respondents did not seek medical advice for their headaches, with the percentage higher in rural areas. Those people thought that over-the-counter pills could be a solution, and that migraines are incurable. The prevalence of symptomatic migraines reached 17.3 percent and peaked in middle age, according to the survey."

"Migraine is the third most common disease in the world, with an estimated global prevalence of 14.7 percent -- affecting nearly one in seven people," Abdelghany explained.

Finding a way out

The experts then turned to the topic of understanding the ailment and the treatments commonly used, as well as tackling the new scientific breakthroughs in the field.

The causes of the disease have long been unclear, and sufferers have often resorted to painkillers that are not effective. Doctors prescribed medications that are usually used for treating other medical problems like heart disease, depression and epilepsy, which could scare patients off and led them to discontinue treatment.

"Many factors contributed to under-recognition and under-treatment, some of which were the absence of specialised headache centres, underestimating headache disorders by family members and even by health care practitioners, insufficient patient education and the availability of over-the-counter pain relievers," said Dr. Maged Abdel Nasser, professor and head of neurology at Kasr Al-Ainy, and general secretary of the Egyptian Society of Neurology, Psychiatry and Neurosurgery.

Though migraine causes are not understood, genetics and environmental factors appear to play a role. Migraines may be caused by changes in the brainstem and its interactions with the trigeminal nerve, a major pain pathway," he added.

This was until a new discovery surfaced.

"Clinical studies have proven that the a certain protein, CGRP, is associated with the migraines and plays an important and active role in causing an attack, and new treatments in the form of monthly shots made use of this scientific breakthrough, and paved the way for the first preventive medication to appear in Egypt when it comes to migraines, Abdel Nasser noted.

Leading cause of disability

The day concluded with attendees drawing attention to the importance of raising awareness of the possibility of preventing and treating migraines, which take a huge toll on economies and societies.

The doctors explained that, between 1990 and 2016, migraines were classified globally as the second leading cause of disability.

They added that more than 90 percent of those who suffer from migraines are unable to work or lead normal lives, and up to 46 percent of migraine patients visit emergency rooms for treatment. Studies show that migraines with aura, a sensation that sufferers get before the onset of an attack, are associated with a twofold increased risk of ischemic stroke.

"In addition to that, migraine patients are at a greater risk of developing anxiety and/or depression than non-sufferers, and the disease is also associated with a high economic and societal burden, Abdelghany said.

"The huge impact of migraine, which affects women three times more than men, on patients lives, translates into significant economic and social burdens," he stressed.

More awareness

Commenting on the lack of proper awareness even among health care providers, Abdelghany, said: Across medical schools all over the world, a minimal amount of hours are dedicated to migraine, despite the fact that severe headaches and migraines are highly prevalent among the younger segment of the population.

"Migraine remains under-diagnosed and under-treated in at least 50 percent of patients, and less than 50 percent of migraine patients consult a physician.

"Awareness should be raised in order for health care professionals, family members and friends to be able to identify the symptoms of migraine and understand that there are treatments, and yes, now there could be prevention," he concluded.

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Migraines at the forefront of Cairo conference - Health - Life & Style - Ahram Online