DNA: The map to your past

Read more: Local, National, International, Education, Community, Health, Consumer, Science, Technology, News, Gene Tree, DNA, Rachel Welte DNA, Welte, Rachel Regalado DNA, Geneology, Scott Woodward, DNA Samples, DNA Kit, Family Tree, Ancestors, Finding your Family Tree, Relatives, Rachel Regalado Family Tree, Rachel Regalado Welte, Colorado Springs, Pueblo, Morning Show, Family

COLORADO SPRINGS, COLO. -- Blue eyes, brown hair, freckles.

We all have unique features, a combination of our relatives past and present.

But the way we look is just the tip of the iceberg, as who we are is written in our DNA.

A complex set of instructions that we inherit from our parents.

With the help of GeneTree, a genealogy research company, I set out on a journey to find my roots, and the origin of my family tree.

Getting started was easy.

I received a DNA kit in the mail from GeneTree.

Inside was a set of instructions, mouthwash, and a baggie.

After swishing for several minutes, I spit my DNA into the cup and sent it on its way, back to GeneTree for processing.

Then, after eight weeks, my results arrived.

Of course, I already had an idea of who, and where my ancestors were from, but the results were still surprising.

"You, out of all the ones (reporters) we have done so far, show two major extremes," Scott Woodward said.

To help me break it all down, I enlisted the help of Woodward, a genealogy expert and founding member of GeneTree.

We began by looking at my mother, and her family.

"When we put your mitochondria DNA into the database, we literally found a thousand people that connect to you," Woodward said.

One of 12 kids, my mom's roots extend back to Europe, the birthplace of many of her ancient relatives.

"If we look at the world today we find people that share your DNA almost exactly, and we find them in the United States, in Switzerland, in Russia, in Yugoslavia, and in Mexico," Woodward said.

And what about famous relatives?

Woodward said I share an ancient maternal ancestor with Marie Antoinette.

"You have a line that goes back to an ancestor, she (Antoinette) has a line that goes back to an ancestor, and they meet somewhere back in the past," he said.

Now for my dad, Richard Regalado (my maiden name).

Where are his predecessors from?

"On your father's side you belong to a group this is called O-3, and O-3 is an Asian type, and we see a lot of people with O-3 in the Philippines," Woodward said.

Which is exactly where my grandfather, Eduardo Regalado, was born and raised.

From there, his roots extend all the way to South East Asia.

"The DNA type is actually older than the use of surnames," Woodward said. "We really did not use surnames until relatively recent, the past 400 to 600 years."

In other words, Regalado is most likely a surname.

An important fact, because Woodward said I have a close connection to a person with the last name Espinoza in Peru.

"There are a lot of interesting possibilities there, and that is where DNA and genealogy can lead to very interesting stories," Woodward said.

So now it is up to me to continue my journey back in time, armed with the knowledge given to me by GeneTree.

If you are wondering how it all works, basically the founders of the company spent years gathering DNA samples from around the world.

For pricing and additional details on the DNA test, click here. 

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DNA: The map to your past

Posted in DNA

DNA technology leads to arrest in Boca Raton home robbery

DNA lifted from a robbery victim's car may have led Boca Raton detectives to the man behind an attack in a woman's garage five months ago.

Lab test results released last week match DNA from the September crime scene to Reache Evans, 36, of Boca Raton, police said.

Evans was arrested Friday on a charge of home invasion robbery.

He is accused of walking into a woman's garage on Southwest 12th Road and grabbing her purse as she arrived home from shopping, police said. The two struggled until the purse strap broke and Evans was able to run off with it, police said.

Crime-scene technicians lifted the DNA from the exterior of the woman's car and sent it to the Palm Beach County Sheriff's Office crime lab. After the match was made, police showed the victim a photo lineup and she identified Evans as her attacker.

Boca Raton police have made several arrests thanks to recent advances in DNA technology.

Blood samples collected at the scene of a home robbery in 2010 led to an arrest 10 months later. The robber had cut himself as he crawled through a ripped window screen to get inside.

A major coup for Boca Raton police was a 2010 arrest in a cold case more than a decade old. John McKenzie, of Boynton Beach, was arrested for attacking a woman in March 1989 and raping her in an apartment.

He sliced off the woman's bathing-suit top, cut her hand and assaulted her. Investigators collected DNA from the scene, but at the time, technology didn't exist to identify him.

McKenzie was convicted of sexual battery and is serving a life sentence in prison. Recent DNA tests linked him to another Boca Raton rape case from 1987, resulting in additional sexual-battery charges against him.

A shared law enforcement database allows police to match DNA samples collected years ago to offenders in the system. The more the database grows, the more likely a match can be made.

apcampbell@tribune.com or 561-243-6609.

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DNA technology leads to arrest in Boca Raton home robbery

Posted in DNA

Amity Institute of Biotechnology hosts conference on perspectives in phyllosphere biology

NOIDA (Uttar Pradesh), Feb.16 (ANI): The Amity Institute of Biotechnology is hosting a three-day international conference on 'Perspectives in Phyllosphere Biology'.

Inaugurated on Wednesday by Dr. Karl. R. Matthews, Professor, Department of Food Science, Rutgers University, USA, the conference includes lectures by several renowned professors and researchers.

The aim of the conference is to discuss the important phyllosphere biology researches, and the importance and scope of the field

Dr. Matthews presented his study on human pathogens ability to colonize plants: induction of plant responses at molecular level.

He stated that pathogens from human sources can easily get transferred to plant bodies, in turn infecting them. Various forms of pathogens, especially bacteria are found in humans, which gets transferred to plant surfaces and grow on them, making them unhealthy to consume in raw form, he added.

He emphatically revealed that there have been over 82 outbreaks of microbes recorded in green leafy vegetables especially spinach, lettuce, tomatoes all over the world from 1996- 2008, thereby increasing the cases of food borne illnesses which accounts for over 21.9 percent of all illnesses.

The incidences of various microbes, especially pseudomonas, bacillus and streptococcus detected in vegetables grown in Delhi/ NCR is increasing due to increase in the consumption of imported foods and fruits and vegetables.

Dr. Mathews advised consumers to pick up fruits and vegetables without spots, which otherwise could lead to food poisoning

Dr. Ashok .K. Chauhan, Founder President of the Amity Group, expressed his desire to increase the research works being carried out in the area of phyllosphere biology so that path breaking results could be achieved.

He also announced the formation of two new societies in Amity - The Society for Phyllosphere Biology and the Society for Microbial Ecology.

Among the other experts participating in the conference are Dr. Krishnendu Acharya, Dr. Gayathri Subbiah, Dr. P.D. Sharma, Dr. Sapna Sharma, Dr. P. Malathi, Dr. P.K.Paul and Dr. V. Bhuvaneshwari.

The conference ends on Friday. (ANI)

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Amity Institute of Biotechnology hosts conference on perspectives in phyllosphere biology

The science behind frontotemporal dementia

When Times staff photographer Rob Gauthier and I first visited the Bryant family last April to begin reporting a story, (“Little-known brain disease rips apart lives of victim, loved ones,”), about a rare type of dementia, known as frontotemporal dementia, we realized that we needed to explore the science behind the malady. FTD, as the disease is known, is similar to Alzheimer's but affects the front portions of the brain and leads to behavioral problems such as the Bryants experienced with Stu.

I knew about Phineas Gage, the railroad foreman who in 1848 lost the front portion of his brain in a terrible construction accident and who survived as a radically changed man. I had read the work of Hanna and Antonio Damasio, neuroscientists who almost 20 years ago pioneered our understanding of the biology of emotions, and I was eager to see how frontotemporal dementia was being studied to further this research. 

In the course of our reporting, Rob and I took a number of trips to UCLA and the West Los Angeles Veterans Affairs hospital to interview Mario Mendez, the physician and neuroscientists treating Stu. In our conversations, Mendez helped us understand what Oliver Sacks meant when he wrote, “Without the great development of the frontal lobes in the human brain, civilization could never have arisen.”

By studying the effects of frontotemporal dementia – and its slow diminishment of personality – Mendez is able to see more clearly the so-called social brain, a portion of our frontal and temporal lobes that plays a role in allowing us to successfully interact with each other and build relationships. Take away this portion of the cortex and we are no longer able to moderate our emotions. 

Moderation – the inhibition of emotional impulses – can take the form of empathy and embarrassment and is critical in helping us negotiate complex social environments. Without either, as Rob and I learned during the time we spent with Stu, humans grow untethered to the world, unable to read feelings or behave in an appropriate manner.

By steering the discussion about morality, normally the providence of ethicists and philosophers, away from the symposium and putting it inside the laboratory where thoughts are considered to be not so much conscious choices, but instead reflexes based on a neurological network, Mendez and other neuroscientists are furthering the inquiry into the nature of right and wrong. In this light, religion, family, even Freud's notions of superego, ego and id matter less than biology.

Mendez argues that specific behaviors – not harming another person, respecting hierarchy and authority, accepting communal goals, recognizing equity and fairness – evolved among humans.  Good manners, therefore, have as much to do with what we are born with as they do with how we were raised and what our parents taught us.

“Much of the social behavior that we take for granted and that we often consider to be learned or cultural or developmental is actually behavior that is deeply ingrained in the nervous system and in the frontal lobes,” Mendez says.

Consider that the next time you’re in a crowded restaurant and watching the kaleidoscope of interactions. Never mind the ability to speak and communicate. Never mind the opposable thumbs. The frontal lobes make humans human.

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The science behind frontotemporal dementia

Hernando County Science and Engineer Fair winners

By Paulette Lash Ritchie, Times Correspondent
Paulette Lash RitchieTampa Bay Times In Print: Thursday, February 16, 2012

The Hernando County Science and Engineer Fair was held Feb. 2 at the Hernando County Fairgrounds. On Feb. 8, the winning projects were announced at the senior (high school) and junior (middle school) levels.

One hundred forty-one students participated in the district fair, and students scoring an average of 48 points or higher were selected to compete at the State Science and Engineering Fair in Lakeland, April 3-5.

Senior (high school)

Botany: First place, Sabrina Impreso, Springstead; second place, Bryn Buckner, Springstead, and Janet Ho, Weeki Wachee; third place, Stephanie Kidd, Hernando.

Behavioral Science: First place, Bailey Brannan, Weeki Wachee.

Chemistry: First place, William Vonada, Springstead; second place, Hanora M. Cassels, Springstead; third place, Natalya Davis, Springstead.

Computer/math: First place, Margherita Prestigiacomo, Springstead; second place, Christopher Stier, Nature Coast; third place, Stephen Skipper, Hernando.

Engineering: Second place, Alyssa Cooper, Nature Coast.

Environmental science: First place, Nicole Sills, Florida Virtual School; second place, Annie McGrath, Springstead; third place, Delaney Rose Ahrens, Hernando.

Earth science: First place, Ying Grace Li, Hernando Christian Academy.

Medicine and health sciences: First place, Shamir Qureshi, Springstead; second place, Josh Crane, Springstead; third place, Christine Sniffen, Nature Coast.

Physics: First place, Brandon Geiger, Springstead; second place, Erin Moynihan, Weeki Wachee; third place, Katie Barta, Springstead.

Zoology: First place, Addison Hilyard, Central; second place, Savanna Wells, Hernando.

Junior (middle school)

Botany: First place, Brett Maharaj and Nate Rushnell, Challenger; second place, Jordan Ranfone, Challenger, and Ruby Graham, Notre Dame Catholic School; third place, Hanna Crider, Powell, and Shawenda Alexis, West Hernando.

Behavioral science: First place, Emily McHugh, Challenger; second place, Kristina McCane, Challenger; third place, Kallie Carlton, Powell.

Chemistry: First place, Katie Sinsko, Challenger; second place, Vasu Mahlotra, Challenger; third place, Kenzie Phillips, Powell.

ComputerS: First place, Ashton Hunter, Challenger.

Earth space: First place, Alexa Lacy, Challenger; second place, Billy Marquis, Challenger; third place, Xavier Graham, J.D. Floyd.

Environmental science: First place, Holden Jung, Challenger; second place, Taylor Rejsek, Challenger; third place, Pierce Kimbrough, Challenger.

Engineering: First place, Allyson Fielder, Challenger; second place, Richie Hopper, Challenger; third place, Sasha Garcia, J.D. Floyd.

Medicine and health sciences: First place, Rahne Skoglund, Powell; second place, Eduardo Davila-Garcia, Challenger; third place, Katrina Nelson, Challenger.

Physics: First place, Joe Lacy, Challenger, and Heather Jacobs, Methodist School Center; second place, Zachary Dill and Karli Kimbrough, Challenger; third place, Ivey Whitaker, Methodist School Center, and Carl Boutin, Challenger.

Zoology: First place, Cole Kolasa, Challenger; second place, Sidney Dill, Challenger; third place, Devon Dupuis-Salado, West Hernando.

Moving on

These students are eligible for the State Science Fair:

Junior Division: Rahne Skog-lund, Heather Jacobs, Holden Jung, Emily McHugh, Kristina McCane, Joe Lacy, Alexa Lacy, Taylor Rejsek, Brett Maharaj, Zack Dill, Sidney Dill, Cole Kolasa and Eduardo Davila-Garcia.

Senior Division: Sabrina Impreso, Shamir Qureshi, Josh Crane, Ann McGrath, Margherita Prestigiacomo, Christine Sniffen, Addison Hilyard, Delaney Rose Ahrens, Bailey Brannan, Janet Ho and Nicole Sills.

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Hernando County Science and Engineer Fair winners

Gold Skin Care Center in Nashville Among The First to Offer Non-Invasive and Painless TriPollar Anti-Aging Treatments

U.S. clinical study shows 100% satisfaction rate for safe and effective procedure

Nashville, TN (PRWEB) February 16, 2012

Gold Skin Care Center is now offering TriPollar treatments—powered by the world's most advanced radiofrequency (RF) technology—via a device called Apollo, internationally touted for its effective and painless treatment of sagging skin, wrinkles, cellulite, circumferential reduction and the ability to tone and tighten skin of both the face and body. The treatment is completely painless and safe and is effective on all skin types and colors. TriPollar is newly available in the U.S. following an exclusive partnership between Pollogen, a global leader in the medical aesthetics market, and Lumiere Medical, a premier U.S. distributor of cutting-edge, clinically-validated technologies.

Patients benefit from both visible immediate and long-term results. The immediate effects include a smoother, tightened appearance and texture of the skin. Most clients realize the desired outcome at the conclusion of a full treatment course—a recommended 6-8 sessions—with a noticeable reduction in wrinkles and fine lines, body contouring and lifting of the treatment area, and improved tone and texture.

Although the Apollo is FDA cleared for the non-invasive treatment of mild to moderate facial wrinkles, the 30-minute, no-downtime procedure is CE approved for circumferential reduction and the reduction of cellulite and has become the treatment of choice internationally for these currently off-label non-invasive body contouring applications.

The safety and efficacy of TriPollar treatments have been proven in multiple clinical studies and published in eight peer reviewed articles. A recent U.S. clinical study showed a 97% improvement following a full series of treatments, and 100% of the patients reported that they were satisfied with their results.

“In the short time since we’ve begun offering the Apollo at Gold Skin Care, patients are already expressing satisfaction with the results and the pleasant and pain-free experience,” says Dr. Michael Gold, founder and Medical Director of Gold Skin Care Center. “I’m extremely impressed by the technology’s efficacy and safety.”

The Center is located at 2000 Richard Jones Road, Suite 220, in Nashville. For more information, call 615.383.2400 or visit http://www.goldskincare.com. For additional before and after images, please visit http://www.pollogen.com/Before-And-After/Facial-Contouring.html.

About Gold Skin Care Center

Gold Skin Care Center is one of the leading clinical and cosmetic dermatology centers in the country, offering the most advanced and effective procedures available today. The Center’s three distinct divisions include the Laser & Rejuvenation Center, solely devoted to the aesthetic needs of patients; the Advanced Aesthetics Medical Spa, offering the most advanced techniques and products for relaxation and rejuvenation; and the Tennessee Clinical Research Center, where the most advanced laser and light based sources are researched before they are available to the general public. Dr. Michael Gold, founder and medical director of the Gold Skin Care Center, is also an assistant clinical professor in the Department of Medicine, Division of Dermatology, at Vanderbilt University Medical School and at Vanderbilt University Nursing School. For more information, call 615.383.2400 or visit http://www.goldskincare.com.

About Pollogen

Pollogen Ltd. is a global leader in the medical aesthetic market providing innovative, safe and effective solutions that enhance and expand the practices of medical aesthetic professionals. The company offers products to address a range of skin treatments under the industry’s three premier brands: TriPollar®, TriLipo® and TriFractional™. Pollogen offers a full line of clinically-proven, non-invasive anti-aging facial and body contouring treatment platforms for circumference reduction, cellulite reduction and skin tightening. The company’s medical aesthetic devices, Maximus, Apollo, and Regen XL offer customers clinically-proven, safe and effective anti-aging lunchtime beauty treatments that deliver immediate and long-lasting results. With a distribution network in over 60 countries, Pollogen is providing innovative solutions to medical professionals globally.

About Lumiere Medical

Lumiere Medical, the premier U.S. distributor of innovative, science-based, clinically validated technologies, presents new revenue opportunities for its customers while providing results which consistently deliver high patient satisfaction. The exclusive U.S. distributor for Pollogen Ltd., Lumiere has recently added the Apollo TriPollar RF device to its distribution network, offering safe and effective anti-aging treatments with both immediate and long-lasting results.

###

Susan Woods
Crier Communications
3102741072
Email Information

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Gold Skin Care Center in Nashville Among The First to Offer Non-Invasive and Painless TriPollar Anti-Aging Treatments

Grey's Anatomy: Ellen Pompeo Opens Up About Baby "Guilt," Her TV Marriage and Cristina's Crisis

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MORE SCOOP FROM THE SET: Grey's Anatomy/Private Practice Crossover Scoop: Paul Adelstein and KaDee Strickland Talk Baby-Mama Drama and Baby Making!

In real life, how has it been juggling the show and being a mom to your beautiful daughter, Stella?
It is challenging. You know, I have my days where I feel really guilty that I've been here every day if I have to work a lot. But the truth is I'm in a very blessed situation, I am so lucky. First of all, I am so lucky to live in a country where a girl like me can make this kind of living, achieve her dreams and reach her goals. And I don't think anywhere else in the world can girls have the freedom that we do here to have these amazing careers and be mothers. So first I'll say it really isn't a challenge with respect to the women in the rest of the world, I think we're very lucky. And all working moms have their challenges and I'm incredibly lucky compared to most. I can afford help and I'm fortunate where I can bring her here if I miss her. She's not in preschool yet so she can spend time on set with me. So I think everything in my life is a blessing. I've got my little challenges, but they're insignificant compared to what real working moms go through.

That's great that she can look up to you in that way and see what a woman of today can look like.
Absolutely, and how we can have whatever we want. And I strive to be a better person everyday because of her.

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Grey's Anatomy: Ellen Pompeo Opens Up About Baby "Guilt," Her TV Marriage and Cristina's Crisis

Grey's Anatomy-Private Practice Crossover Scoop: Paul Adelstein & KaDee Strickland Talk Baby-Makin'!

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Charlotte and Cooper's new marriage certainly has been tested this season. First, he found out he has a son, Mason (Griffith Gluck) from a fling he had eight years ago with Erica (A.J. Langer), and juuuust when that reality had sunk in, they learned Erica has life-threatening illness that needs some highly specialized medical treatment.

If only they knew a (Mc)Dreamy brain surgeon! Oh right. They totally do.

In Thursday's Grey's Anatomy, Derek Shepherd's li'l sis Amelia (Caterina Scorsone) brings Erica to her big bro in Seattle to try to save her life, and Charlotte and Cooper come along for the ride to support Mason.

"We're looking for a miracle honey!" Kadee told me on the set of Grey's while filming, hinting to the mere seconds it may come down to to save Erica's life. "Yeah, it's a big deal. That's why we traveled. We can't leave our practice and our hospital for just anything!  We're here visiting the Dr. Shepherd family, and Chyler Leigh (Lexie Grey) which is great. We're having so much fun [on the Grey's Anatomy set]...It's kind of like a bizarre dream we're all living out."

Char-Coop fans have been dying to know if the couple might have a child of their own, and good news! Paul says he thinks it's becoming more and more of a possibility. "One of the fun things about it is that Charlotte is at best ambiguous about having kids," he explains. "And this [Mason] thing has been like thrusted into her lap. And Cooper of course has always wanted kids. So it almost works for them…It's really going to beg the question about whether they have their own because Charlotte has really taken to Mason now."

KaDee, for the record, is all for Char getting knocked up! "I would love to practice a waddle!" she laughs. "I just think that would be so fun. In my little cheap jacket, just walking around, be in a bad mood and having to puke, it would be good." You hearing this, Shonda Rhimes? Ratings. Gold. (Or maybe not but we would love it.)

So tomorow night, will Erica survive? Paul admits "We do know" but of course, they ain't spillin' cause they don't want their characters contracting a case of the "gonna die"'s, too. Kadee simply says she hopes Erica sticks around because she has a "mad crush" on actress A.J. Langer. Fair enough.

On that note…any chance Charlotte and Cooper will get back to some of their racier romance scenes? Where has the kink-tastic love gone? Get all the scoop from KaDee and Paul on that—plus why she was mortified to watch a recent episode of The Soup that made fun of her!—in our exclusive video interview from the Grey's Anatomy set.  Warning: It'll make you crush on them more.

The Grey's Anatomy-Private Practice crossover airs tomorrow night on ABC on both series. Don' t miss it!

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Grey's Anatomy-Private Practice Crossover Scoop: Paul Adelstein & KaDee Strickland Talk Baby-Makin'!

First local dogs receive ‘amazing’ stem-cell therapy

Just before 10 a.m. Tuesday, Jake — a hobbling, 12-year-old yellow Labrador retriever — went into surgery at the Stanley Veterinary Clinic in Overland Park with crippling arthritis, no longer able to run without pain or even walk down stairs.

He had already been on months of medications that seemed to turn the normally happy dog sad. And hip and joint replacements costing tens of thousands of dollars were not feasible, said owners Mike and Elizabeth LeBlanc of Leawood.Still, their 8-year-old daughter, Mia, had just one request at Christmas. “All I want is for Jake to feel better,” she wrote.So, on Tuesday morning, Jake became one of the first canines in the Kansas City area to undergo a somewhat new and controversial procedure in which stem cells were harvested from the fat of his own body and then injected into his joints. The expectation is that within a few weeks the cells will regenerate missing cartilage and turn his arthritic joints healthy again.“It’s amazing,” said veterinarian Les E. Pelfrey, who conducted the procedure. “A few weeks later, these guys are running up and down.”The stem-cell procedure, which has gained notice in recent years with anecdotal stories of success on YouTube and cable television, remains controversial not only for its quick adoption in veterinary clinics nationwide, but also because some researchers say it remains scientifically unproven and expensive, at $1,800 or more per treatment.“Let me tell you one thing,” said James L. Cook, a professor of orthopedics at the University of Missouri’s College of Veterinary Medicine. “I don’t want to write off stem cells. Stem cells may hold the key for truly restorative medicine.”In horses, stems cells have been shown to help rejuvenate damaged tendons and other problems. They are being tested for cardiac problems.“But in the joints for dogs with arthritis? No way,” Cook said. “I would never recommend anyone get this done.”Stem cells essentially are the equivalent of young and impressionable cells whose genetic gears have yet to determine their fate. Because they are so young, they theoretically can turn into any kind of cell, from cartilage to neurons. In humans, stem cells have long been held out as possible therapy for diseases such as Parkinson’s.The problem, Cook said, is that although a few studies have shown that the injection of stem cells into arthritic canine joints does reduce pain, compared with “control” dogs not injected with stems cells, no studies have convincingly shown that stems cells are any better at helping dogs than the current, and less expensive, standard of care. That typically involves a combination of weight loss, pain medications and, when necessary, injections of hyaluronic acid, a slippery substance that often goes missing in arthritis. Those injections, given a couple of times a year, cost less than $100 each.Moreover, even if the stem cells work, no one knows at this point how long the improvement will persist, although some vets have noted benefits lasting a year or more.“We know for sure that it (stem cell injections) does have some palliative effects. It can make symptoms better,” Cook said. “And we do know for sure that it does not regenerate cartilage in arthritic joints. The palliative effects are not as good, or no better, than hyaluronic acid injections.”That is far from the case being made by companies now promoting stem-cell therapy in dogs, or owners who believe in it.A number of stem-cell companies have emerged in recent years. Chief among them are Vet-Stem, based in Poway, Calif., and MediVet America, a division of MediVet, based in Sydney, Australia, which notes that it is currently conducting studies on canines, stem cells and cartilage regeneration.Both use largely similar technologies and methods. At the vet’s office, the dog undergoes a quick procedure in which a bolus of fat about the size of a golf ball is taken from above the shoulder.The fat is processed and treated with chemicals to extract millions of stem cells. Some of those cells are then injected into a dog’s damaged joints; the rest enter the body through an intravenous line into the bloodstream.One prime difference between the Vet-Stem and MediVet systems is that Vet-Stem costs about $3,000 or more.Vet-Stem requires the veterinarian to ship the fat sample to California, where it is processed and sent back for injection. Several dogs in the Kansas City area have been injected with stem cells from Vet-Stem.The MediVet system costs pet owners about $1,800. It provides veterinarians with a kit to process the stem cells in their own offices over about four hours. Dogs are injected with stems cells on the same day the fat is removed. The pet typically goes home the next day.In Topeka, the University Bird and Small Animal Clinic has used the MediVet kit and system with what it says are positive results on about 40 dogs since November 2010. A veterinarian there, Larry Snyder, helped train Pelfrey in Overland Park.Snyder came to the clinic two weeks ago to perform the procedure on another hobbled yellow Labrador retriever, Milo, owned by dentist Jon Finley and his wife, Sharon, in Leawood.“Dr. Pelfrey and Mrs. Finley didn’t tell me how much this procedure was going to cost,” Jon Finley said, “and I’d rather you not tell me. No matter what, he’s walking better, standing upright, feeling better. I can’t help but think he’s going to get better and better.”Jake’s owner said that, whatever the outcome, she knows that the procedure is not a cure.“I’m hoping this gives him a better quality of life,” Elizabeth LeBlanc said. “I got him when he was just 6 weeks old. He was such a blessing. It will be worth it, even if I can give him one more great summer.”

To reach Eric Adler, call 816-234-4431 or send email to eadler@kcstar.com.

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First local dogs receive ‘amazing’ stem-cell therapy

Stem Cell Stocks Skyrocket in 2012 — Cytori Therapeutics and Cord Blood America on the Upswing

NEW YORK, NY--(Marketwire -02/15/12)- Stem cell stocks have performed well of late, outperforming the S&P 500 by a large margin over the last three months. Since mid-November, TickerSpy's Stem Cell Stocks index (RXSTM) has returned more than 20 percent, as favorable news from some of stem cell industry heavyweights has boosted investor optimism in the sector. The Paragon Report examines investing opportunities in the Biotechnology Industry and provides equity research on Cytori Therapeutics, Inc. (NASDAQ: CYTX - News) and Cord Blood America, Inc. (OTC.BB: CBAI.OB - News). Access to the full company reports can be found at:

http://www.paragonreport.com/CYTX

http://www.paragonreport.com/CBAI

Shares of Cytori Therapeutics have skyrocketed nearly 70 percent year-to-date. The company develops, manufactures, and sells medical products and devices to enable the practice of regenerative medicine. The Company's technology is the Celuion family of products, which processes patients' adipose-derived stem and regenerative cells (ADRCs) at the point of care.

In late January, Cytori received an Investigational Device Exemption (IDE) approval from the U.S. FDA to begin the "ATHENA" trial. ATHENA will investigate the use of the Celution System to treat a form of coronary heart disease, chronic myocardial ischemia (CMI).

The Paragon Report provides investors with an excellent first step in their due diligence by providing daily trading ideas, and consolidating the public information available on them. For more investment research on the biotechnology industry register with us free at http://www.paragonreport.com and get exclusive access to our numerous stock reports and industry newsletters.

Cord Blood America, Inc. is a holding company that, through its subsidiaries, is engaged in the business of collecting, testing, processing and preserving umbilical cord blood, thereby allowing families to preserve cord blood at the birth of a child for potential use in stem cell therapy.

USA Today recently reported that umbilical cord blood stem cells have been successfully used to treat individuals with type 1 diabetes, highlighting the importance of storing stem cells at birth. The USA Today article says that stem cells from cord blood have been used to "reeducate" the immune system T cells of people with type 1 diabetes so their pancreas started producing insulin again - thereby reducing the amount of insulin they needed to inject.

The Paragon Report has not been compensated by any of the above-mentioned publicly traded companies. Paragon Report is compensated by other third party organizations for advertising services. We act as an independent research portal and are aware that all investment entails inherent risks. Please view the full disclaimer at http://www.paragonreport.com/disclaimer

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Stem Cell Stocks Skyrocket in 2012 -- Cytori Therapeutics and Cord Blood America on the Upswing

AccelPath, LLC Provides Business Plan Overview for 2012

GAITHERSBURG, MD and WESTWOOD, MA--(Marketwire -02/15/12)- AccelPath, LLC, ("AccelPath" or the "Company"), a wholly-owned and operating subsidiary of Technest Holdings, Inc. (OTC.BB: TCNH.OB - News), provides its business plan overview for 2012. AccelPath was acquired by and took over operating control of Technest Holdings, Inc. on March 4, 2011.

Before 2012, the Company was developing its core workflow technology. A portion of this development enabled completing the "loop" of total digital transfer of pathology case information from histology laboratories to prominent institutional pathologists and back to referring physicians. These physicians require accurate, reliable pathology reports to immediately begin patient treatments. The Company began generating revenues in 2011 utilizing its newly-developed technology.

"We are pleased that, since AccelPath was formed, we have been able to achieve our growth and infrastructure development objectives," said Shekhar Wadekar, the Company's Chief Executive Officer. "We believe 2012 should be another exciting year for the Company, particularly as we expect to implement our digital pathology workflow solution, continue to expand our services and increase customer penetration using our successful and motivated sales force. With our experienced management team, we expect to meet the milestones we have established for 2012 and beyond."

About AccelPath

AccelPath provides technology solutions that play a key role in delivering information required for diagnosis of diseases and other pathologic conditions with and through its associated institutional pathologists. The medical institutions, with whom the Company partners, prepare comprehensive diagnostic reports of a patient's condition and consult with referring physicians to help determine the most appropriate treatment. Such diagnostic reports enable the early detection of disease, allowing referring physicians to make informed and timely treatment decisions that improve their patients' health in a cost-effective manner. The Company seeks out referring physicians and histology laboratories in need of high-quality pathology interpretations and manages HIPAA-compliant digital case delivery and reporting while developing comprehensive solutions for managing medical information.

AccelPath is currently focused on the $14 billion anatomic pathology market in the US. The Company's business model builds upon the expertise of experienced pathologists to provide seamless, reliable and comprehensive pathology and special test offerings to referring physicians using conventional and digital technologies. The Company establishes longstanding relationships with the referring physicians as a result of focused delivery of its partner's diagnostic services, personalized responses and frequent consultations, and its proprietary flexible information technology, or IT, solutions that are customizable to the referring physicians' or laboratories as well as the pathologists' needs. Such diagnostic reports often enable the early detection of disease, allowing referring physicians to make informed and timely treatment decisions that improve their patients' health in a cost-effective manner. AccelPath's IT and communications platform enables it to efficiently and securely deliver diagnostic reports to referring physicians. In addition, AccelPath's IT platform enables close tracking and monitoring of medical statistics.

Technest focuses on the design, research, development and integration of three-dimensional imaging devices and systems primarily in the healthcare industries. The Company also develops solutions and intelligent surveillance devices and systems, as well as three-dimensional facial recognition systems for security and law enforcement agencies. Historically, the Company's largest customers have been the National Institutes of Health and the Department of Defense. The Company's solutions leverage several core proprietary technology platforms, including 3D imaging technologies.

Additional Company information may be found on the Internet at: http://www.accelpath.com.

Forward-Looking Statements

This press release contains certain "forward-looking statements" relating to the business of the Company, which can be identified by the use of forward-looking terminology such as "may," "will," "expect," "anticipate," "intend," "estimate," "believe," "project," "continue," "plan," "forecast," or other similar words, or the negative thereof, unless the context requires otherwise. These statements include, but are not limited to, statements about the Company's expected future performance and achievement of milestones. The results anticipated by any or all of these forward-looking statements may not occur. In addition, these statements reflect management's current views with respect to future events and are subject to numerous risks, uncertainties and other factors that could cause actual results to differ materially from those set forth in or implied by these forward-looking statements. Factors that could affect those results include, but are not limited to, the acceptance of our solutions in the marketplace, the efforts of our sales force, general economic conditions, and those described in the Company's reports on Forms 8-K, 10-Q and 10-K and proxy statements and information statements, which have been or will be filed by the Company with the Securities and Exchange Commission (the "SEC"), including without limitation under the caption "Risk Factors" in the Company's Annual Report on Form 10-K filed on October 13, 2011. Many of the factors that will determine the outcome of the subject matter of this press release are beyond the Company's ability to control or predict. The Company undertakes no obligation and expressly disclaim any obligation, to revise or publicly update any forward-looking statements, or to make any other forward-looking statements, whether as a result of new information, future events or otherwise.

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AccelPath, LLC Provides Business Plan Overview for 2012

Limasawa named Galing Pook awardee for nutrition program

Pres. Benigno Aquino III hands over to Mayor Melchor Petracorta the most coveted Galing Pook plaque. Photo courtesy of Malacañang Press Bureau

MAASIN CITY, SO. LEYTE – The Book of Proverbs 29:18 says “Where there is no vision the people perish.” This simple line could be Mayor Melchor Petracorta’s driving vision, as he led the small island town of Limasawa to national fame when his innovative nutrition program was hailed as one of the country’s “Galing Pook 2011” awardees. The town got the most coveted citation and usually, a prize of P1,000,000 in the form of projects come with it.
This, after Limasawa received the Highest Nutrition Award in 2011 in the country and bagged P 500,000 for the feat. Previous to that, Limasawa was the consistent regional level winner for three consecutive years.  The same innovative nutrition practice got the nod of the judges of the recent national Galing Pook Award. Limasawa is the only awardee in Eastern Visayas this year.
Limasawa is the second LGU in the region to win the prestigious and much-coveted award, the first being Palompon, Leyte in the ‘90’s for its program for a sustainable marine ecology, then under Mayor Ramon Oñate who has made a comeback.
Limasawa, a town of 5,800 residents, has almost achieved zero malnutrition among its schoolchildren and was able to encourage a majority, if not all, of its adults to adopt a healthy lifestyle. From having a high malnutrition rate six years ago among its schoolchildren, it was dramatically dropped to only 2.8% in 2011.
Limasawa, a 6th class municipality, has proven that being a “poor” town is not a hindrance to win national awards for its programs to improve the lot of its constituents. Limawasa is also known as the site of the first mass in the Philippines, where explorer Ferdinand Magellan first set foot over 400 years ago. It has also one of the best diving sites in the country.
Mayor Melchor Petracorta personally received the town’s Galing Pook award from Pres. Simon Benigno C. Aquino III together with the municipal council members on January 30 at the Rizal Ballroom in Malacañang Palace.
P-Noy, in his speech, lauded Limasawa’s achievement saying that “a poor municipality can effect a lot of positive change for its people if there’s cooperation among leaders and its residents. Limawasa, once a face of hunger and malnutrition, is now a town of healthy community.  Because of cooperation from all sectors, their feeding program and livelihood skills trainings are successful.”
The Galing Pook Awards aims to recognize innovations and excellence in local governance. Its ultimate goal is to help foster democratic governance, strengthen and professionalize government, and empower communities to encourage citizen participation in local governance. The award was instituted in October 1993 when the Local Government Code took effect.
Mayor Petracorta, in an interview before he left to receive the award, said the accolade was not his alone. “This is a collaboration of all agencies and a constituency that wants to ensure a healthy and nutritionally well community.”
Healthy citizens
are assets
An unknowing reader would probably think Mayor Petracorta is a doctor, with his vision of a healthy citizenry. But he is not. He is an accounting graduate and a barrister. Maybe, that is also why he thinks healthy citizens are “assets”.
In a previous interview with him, Petracorta said that for six years from 2005 – 2010, they made every effort to ensure that constituents in their municipality are all healthy and nutritionally well.
For three years, in 2005-2007, the town was a consistent Banner Year Awardee and became the recipient of the CROWN Award or the Consistent Regional Outstanding Winner in Nutrition Award from 2008-2010.
To improve the nutritional status Limasawa’s folk and children, the Municipal Nutrition Council (MNC) launched different projects to address the concern.
Among these are the  “Gulay Bawat Bahay – Hahaba ang Buhay” where each family should plant vegetables and encourage their children to eat them.  They also started communal gardens using organic fertilizers dubbed as “Halaman ng Bayan Para sa Kalusogan ng Mamamayan”. There are also periodic contests like the “Tatay Ko Kaagapay sa Kalusogan” program for fathers and “On-the-Spot Cooking Contests” to come up with delicious and nutritious food from ingredients made available.
To make sure that infants are born nourished and their mothers healthy, they started a feeding program every Friday for pregnant women and periodic prenatal checkups.
They also encouraged the “4 o’clock habit” – group exercises among LGU workers and constituents and those who don’t join are fined. Incentives are also given to  “Biggest Losers”.
Also, after identifying the families with undernourished children, they set in motion the “Handog Tulong Alaga” where the families were consulted and made to suggest ways of how the local nutrition council can help them. Milk and eggs were also provided to the kids until they reached standard weight.
Mayor Petracorta said that they made the nutrition program inclusive, involving all – the LGU, well-off citizens and the program beneficiaries themselves.
“This award proves that when a community is united, focused and work together for a common goal, they can surpass difficulties and achieve their goals and dreams.  Having good and sustainable nutrition programs means a healthy and brighter future for the community.  We want to share these good nutrition practices to other LGU’s for a healthier Philippines,” said Mayor Petracorta.
To sustain the nutrition programs, they have the “Buntis Baby Bank” which is funded from fines imposed on illegal fishers and even from non-participation in the 4 o’clock habit. Ten percent of its income from diving fees also goes into the bank.
Another pride of
Southern Leyte
Limasawa’s feat is another feather on the cap of Southern Leyte. Governor Damian “Mian” Mercado said he is happy for Limasawa’s success, pledging the provincial government’s continued support to all its nutrition initiatives. Mercado is also the chairman of the Southern Leyte Provincial Nutrition Council.
For her part, National Nutrition Council regional coordinator Carina Santiago said that “I am really happy for Limasawa.  They really deserve the award.  My hats off to Mayor Petracorta and members of the Municipal Nutrition Committee, and of course to Governor Mercado and Congressman Roger Mercado.  May the award serve as inspiration and motivation to the rest of the local government units in the region to take up the cause against hunger and malnutrition by promoting and investing in nutrition programs in their communities.”
137 programs all over the country were submitted to this year’s Galik Pook Awards. Each were evaluated on its positive impact to society, promotion of people’s participation and empowerment, transferability and sustainability, and efficiency of program service delivery.
The winning programs this year are justice enhancement programs, innovative nutrition programs, and empowerment of indigenous people, among others.
Aside from Limasawa, 16 other LGUs were recognized. They are Barangay San Antonio, Pasig; Barangay Tangos in Baliwag, Bulacan; Sta. Cruz, Laguna; Bingawan, Iloilo; Cagwait, Surigao del Sur; Dumingag, Zamboanga del Sur; and the provinces of Misamis Oriental, Surigao del Sur and Zamboanga del Norte.
Seven other LGUs in the Autonomous Region in Muslim Mindanao (ARMM) were also honored in a new category called “Galing Pook in ARMM”.
These are Kapatagan, Lanao del Sur; Sulu Province; Southwestern Ligawasan Alliance of Municipalities; Wao, Lanao del Sur; Sultan Mastura, Maguindanao; Bongao, Tawi-tawi; and Upi, Maguindanao.

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Limasawa named Galing Pook awardee for nutrition program

SCAN Health Plan Arizona Honors National Nutrition Month with Workshops for Seniors

PHOENIX--(BUSINESS WIRE)--

A healthy diet is essential to better health. In honor of National Nutrition Month in March, SCAN Health Plan Arizona invites seniors to take part in one or all of its nutrition-related presentations and cooking demonstrations during the month. All of the presentations will take place at the SCAN Connections Resource Center at 1313 E. Osborn Road in Phoenix. There is no cost to attend, but space is limited and reservations are required. Anyone interested in attending should call 602-778-3420 to reserve a space.

On March 14 from 10 – 11 a.m. is “Solutions for Life – Nutrition and Longevity,” a medically approved weight-reduction and longevity program that is backed by cutting-edge research. Also on March 14 from 11:30 a.m. – 12:30 p.m. is “Healthy Nutrition on a Budget,” focusing on nutritional guidelines for seniors, nutritious and low cost sample meals and snacks, and community resources. On March 21 from 9:30 – 10:30 a.m. is “Healthy Nutrition for Seniors,” a look at the role of nutrition, portion distortion and nutritional guidelines for seniors in maintaining a healthy weight. Also on March 21 from 11:30 a.m. – 1 p.m. is “Get Your Plate in Shape,” a portion-control and healthy cooking demonstration and sampling.

SCAN Health Plan Arizona also will launch an eight-month series of hour-long workshops focused on living well. The “Wellness Way of Living” workshop will take place on March 28 from 10 – 11 a.m. Participants will discover how every aspect of their lives can influence overall health. Subsequent monthly presentations will explore maintaining a healthy mind and stress management.

“A healthy, well-rounded diet that includes all of the essential nutrients is important at any age, but seniors are particularly vulnerable to the detrimental effects of poor eating habits,” said Dr. Raymond Cogen, SCAN Health Plan Arizona’s chief medical officer. “SCAN Health Plan Arizona hopes to increase awareness among seniors about diet and nutrition, which will support better health, increased energy, a stronger immune system and more.”

For 35 years SCAN Health Plan has been focusing on the unique needs of people with Medicare and today is the fourth-largest not-for-profit Medicare Advantage plan in the United States. SCAN Health Plan Arizona serves approximately 10,000 members in Maricopa and Pima counties. Further information is available at scanhealthplan.com.

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SCAN Health Plan Arizona Honors National Nutrition Month with Workshops for Seniors

Virus Engineering And The Fear Of Science

Three weeks ago scientists around the world agreed on a 60-day moratorium on certain genetic experiments involving the bird flu virus H5N1. I heard the news while driving to work on Monday's Morning Edition.

The halting of research was deemed necessary after scientists in the Netherlands showed that a genetically-modified bird flu virus could pass among ferrets and kill them. The virus, found in wild birds, rarely affects people, and when it does it doesn't spread easily. It is, however, quite deadly. It has killed half of the 500 humans with documented cases. The Dutch group wanted to demonstrate that we should be careful with the virus, that small changes could turn it into a lethal contagious disease that could cause a catastrophic pandemic. By knowing more about the virus and its potential we could better prepare for the worse-case scenario.

 

In proving their point, they raised serious issues concerning the nature of scientific research and its control. So much so that the World Health Organization (WHO) has invited a small group of experts to address these issues, starting tomorrow in Geneva, Switzerland.

The scenario is the stuff of movies. Due to a lab accident, or to ill intention, the modified virus escapes into the open and starts spreading and killing, creating world-wide havoc.

In the public imagination, this is not too different from the mythic tale of Doctor Frankenstein and his monster: a scientist, driven by good intention, ends up creating a monster with its own killing agenda. (At least that's how it is in the more popular Hollywood version of Mary Shelley's brilliant exploration of cutting-edge science and man's ability to control nature.)

Michael Osterholm, who serves on the National Science Advisory Board for Biosecurity, is clearly worried, saying, "It would be foolish to not take this very seriously." Late last year, the Board considered parts of similar research by a group at University of Wisconsin-Madison too risky to be disseminated in the normal way to the scientific community, that is, through the publication of peer-reviewed papers and lectures at conferences.

When scientists feel the need to censure other scientists, you can be sure that fierce debate will follow. After all, one of the most cherished aspects of academic science is precisely its openness: everyone, everywhere should have access to the data and methodology so that results can be replicated, tested, and, usually, improved upon. At least in principle, you should only believe a result when you see it for yourself.

The move to cloister research is a remarkable and worrisome situation. As Keiji Fukuda, from the WHO, declared, "We have viruses which exist, we have manuscripts which have been written, we have a moratorium which was declared voluntarily by the researchers, and so given all of that, you know, what are some of the practical steps that we can take?"

Should this kind of research be forbidden? Should it be relegated to ultra-secure labs, the kinds that store Ebola and smallpox? Should it become a national security priority and put in the hands of the government?

Can safeguards be implemented such that key details of the research are only revealed to legitimate researchers? And how will one determine who is legitimate? This brings back the spying paranoia with nuclear weapons that started in Los Alamos during the Manhattan Project and that ended up costing J. Robert Oppenheimer his security clearance and, to a large extent, his dignity. It is fodder for the worst conspiracy theories which, I am sure, have already begun.

We should learn from the history of the atomic bomb and remember that scientific research can never go back: once it's out it will become available, even if the costs and scientific challenges are high. On the other hand, we should not equate science with Pandora's Box. In the particular case of the H5N1 virus, research aimed at understanding how the virus can pass among people is the best way to make sure it doesn't. Or, if it does, at how to create proper immunization against it. The best that can be done is to have the vaccine ready in case evil intent predicates how the new science will be used.

You can keep up with more of what Marcelo is thinking on Facebook.

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Virus Engineering And The Fear Of Science

DNA evidence presented against Mackowiak

Using DNA evidence, prosecutors Tuesday linked Keith Mackowiak's stained clothing and other evidence to the 2007 double homicide of Aloysius and Catherine Twardowski of Seneca.

Jessica York, an expert forensic analyst from the DNA Diagnostic Center in Fairfield, Ohio, was first on the witness stand to formally introduce and explain how an accredited laboratory deciphers a complex DNA profile.

From evidence supplied by the Illinois State Crime Lab from the investigation of the murders of Twardowskis, York detailed results from her personal scientific examination of gloves believed to have been worn by the defendant during the crime.

The cloth gloves were found by police days after the killings in a fast-food bag discarded on U.S. 6 between Morris and Seneca, following information allegedly suppled by Mackowiak in an interrogation session in July 2007.

The expert said her analysis of the gloves, inside and out, found the DNA profiles were "consistent" with those of Aloysius Twardowski and Mackowiak, meaning there was a good statistical chance blood or other genetic material from both the victim and defendant had been in contact with the gloves.

York added that her DNA analysis found no link to Catherine Twardowski and Mackowiak's next door neighbor and one-time suspect, David Dulabhan of Seneca.

Of Dulabhan's clothes worn by him the week of the murders, York said her forensic testing could not exclude Aloysius Twardowski's DNA from miniscule spots found on his confiscated shorts and shirts.

State's Attorney Brian Towne's has argued that Dulabhan told the truth when he testified last week that Mackowiak "flicked" blood from a victim on him during a return car trip to the Twardowski house by the two former friends the day after the murders.

York's immediate supervisor, Dr. Julie Heinig, verified to the court the DNA results with her own independent review of the data.

As the state's case against Mackowiak enters its second week, more DNA profile evidence is expected to be presented by prosecutors.

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DNA evidence presented against Mackowiak

Posted in DNA

Applied DNA Sciences Reports Fiscal First Quarter 2012 Results

STONY BROOK, NY--(Marketwire -02/15/12)- Applied DNA Sciences, Inc. (OTC.BB: APDN.OB - News) announced its financial results for the fiscal quarter ending December 31, 2011 generating revenues of $516,904.

For the quarters ended December 31, 2011 and 2010, the company generated $516,904 and $317,817 in revenues from operations, respectively. The sixty-three percent (63%) increase in revenues was substantially generated from sales of our SigNature DNA and BioMaterial GenoTyping products. The Company's revenues earned from sale of products and services for the three months ended December 31, 2011 and 2010 included an aggregate of 75% and 52% from four customers of the Company's total revenues, respectively. Three and four customers accounted for 71% and 77% of the Company's total accounts receivable at December 31, 2011 and September 30, 2011, respectively. In fiscal 2011, we increased our customer base by 40%.

The company increased its revenues eighty-four percent (84%) quarter over quarter, from $280,678 for the last quarter of FY'11 ending September 30, 2011 to $516,904 for the first quarter of FY'12 ending December 31, 2011.

Selling, general and administrative expenses increased from $1,329,209 for the three months ended December 31, 2010 to $2,152,428 for the three months ended December 31, 2011. The increase of $823,219, or 61.9%, is primarily attributable to the cost of stock based compensation incurred in the current period compared to the same period last year.

Research and development expenses increased from $20,706 for the three months ended December 31, 2010 to $78,473 for the three months ended December 31, 2011. The increase of $57,767 is attributable to additional research and development activity needed with current operations.

Total operating expenses increased to $2,329,274 for the three months ended December 31, 2011 from $1,442,738 for the three months ended December 31, 2010, or an increase of $886,536 primarily attributable to an increase in equity based compensation and in R&D expenditures.

Net loss for the three months ended December 31, 2011 increased to $2,409,905 from a net loss of $1,344,096 for the three months ended December 31, 2010 primarily attributable to factors described above.

The quarterly report on Form 10-Q, which includes Applied DNA Sciences consolidated financial statements, is available for viewing and downloading, free of charge, through the Investor Relations section of APDN's Web site at http://www.adnas.com, or through the SEC's electronic data system at http://www.sec.gov.

Separately, in response to our overtures, the College Board has indicated that it is not interested in using our technology as a means to identify test takers.

About APDN

APDN sells patented DNA security solutions to protect products, brands and intellectual property from counterfeiting and diversion. SigNature DNA is a botanical mark used to authenticate products in a unique manner that essentially cannot be copied. Our mark provides a forensic chain of evidence that can be used to prosecute perpetrators. To learn more, go to http://www.adnas.com where APDN routinely posts all press releases.

The statements made by APDN may be forward-looking in nature. Forward-looking statements describe APDN's future plans, projections, strategies and expectations, and are based on assumptions and involve a number of risks and uncertainties, many of which are beyond the control of APDN. Actual results could differ materially from those projected due to our short operating history, limited financial resources, limited market acceptance, market competition and various other factors detailed from time to time in APDN's SEC reports and filings, including our Annual Report on Form 10-K, filed on December 8, 2011, our current reports on Form 8-K, and our subsequent quarterly reports on Form 10-Q. APDN undertakes no obligation to update publicly any forward-looking statements to reflect new information, events or circumstances after the date hereof to reflect the occurrence of unanticipated events.

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Applied DNA Sciences Reports Fiscal First Quarter 2012 Results

Posted in DNA

Susan M. Gasser to receive the 2012 FEBS/EMBO Women in Science Award

Public release date: 15-Feb-2012
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Contact: Barry Whyte
communications@embo.org
49-622-188-91108
European Molecular Biology Organization

Heidelberg -- The European Molecular Biology Organization (EMBO) and the Federation of European Biochemical Societies (FEBS) announce Susan Gasser, director of the Friedrich Miescher Institute for Biomedical Research in Basel, Switzerland, as the winner of the 2012 FEBS/EMBO Women in Science Award. Professor Gasser has been recognized for her outstanding scientific research on genome stability and epigenetics and her commitment to mentoring women pursuing a career in science.

The FEBS/EMBO Women in Science Award rewards the exceptional achievements of a female researcher in molecular biology over the previous five years. Winners of the award are role models who inspire future generations of women in science.

The Gasser laboratory studies two research topics of central importance to human health and disease: the maintenance of genome stability through DNA repair, and the role of epigenetic inheritance during tissue differentiation. Susan and her colleagues have examined how the experience of the cell and the environment affects the epigenetic code in different organisms. The Swiss scientist has authored more than 200 scientific articles and reviews over the last thirty years. The implications of her research are far-reaching for human disease, notably cancer. "Susan Gasser is not only a first-rate scientist, but is also playing an important role as one of the most dynamic and successful female scientific leaders in Europe and, indeed, anywhere," stated Gottfried Schatz, Professor Emeritus of Biochemistry at the University of Basel.

"This is indeed a great honour, since being recognized as a top scientist seems harder for a woman than for a man," said the award winner upon hearing of her distinction. "My own success, in any case, reflects that of my team, which balances individual goals with those of the group as a whole. This coordination is a talent women often have."

Mentoring female scientists was a role that she assumed early on in her career. Susan Gasser supported mentoring programmes at the University of Geneva, Switzerland, and the Swiss National Science Foundation. Career and family matters in academic institutions and industry were a frequent topic of her lectures. She has also trained many female scientists in her own laboratory with the result that many of them now run their own labs, and others are in leading positions in industry. "I am very proud of having trained a lot of very successful scientists," said the award winner.

"She clearly represents a role model for female scientists in Europe and beyond," commented Erich Nigg, Director of the Biozentrum, University of Basel, who has followed Susan's scientific career for the past 25 years.

The 2012 FEBS/EMBO Women in Science Award of 10,000 euros will be presented to Susan Gasser on 7 September at the 37th FEBS Congress in Sevilla, Spain, where she will present a plenary lecture.

###

Nominations for the 2013 FEBS/EMBO Women in Science Award close on 15 October 2012. For more information, please visit: http://www.embo.org/policy-and-society/women-in-science/women-in-science-award.html or http://www.febs.org/women-award.

Biosketch

Susan Gasser studied biology at the University of Chicago and completed her PhD at the University of Basel, developing an assay for the import of mitochondrial proteins with Gottfried Schatz. During her postdoctoral studies she examined questions of metaphase chromosome structure and higher-order organization of DNA in Drosophila nuclei.

Between 1986 and 2001, she led a research group at the Swiss Institute for Experimental Cancer Research in Epalinges, Switzerland, focusing on the functional implications of chromosomal organization in Saccharomyces cerevisiae. In 2001, she became a professor at the Department of Molecular Biology at the University of Geneva, Switzerland. Since December 2004, she is Director of the Friedrich Miescher Institute (FMI) for Biomedical Research in Basel and Professor of Molecular Biology at the University of Basel.

Professor Gasser has served nine years as a member of the Swiss National Science Foundation Council, she was Vice-chair and Chair (as of 2003) of the EMBO Council, and currently sits on numerous editorial boards, review committees and advisory boards. She has been awarded several prizes, including the Otto N?geli Prize 2006, the INSERM International Prize 2011 and the Medal of Honor from the Charles University in Prague.

Contact Susan Gasser: Sandra Ziegler; Head, FMI Communications; Phone: 41-61-696-1539; sandra.ziegler@fmi.ch

Contact FEBS: Lea Sistonen; Chair of FEBS Women in Science; Phone: 358-50-4013513; lea.sistonen@btk.fi

Contact EMBO: Barry Whyte; Head, EMBO Public Relations & Communications; Phone 49-6221-8891-111; communications@embo.org


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Susan M. Gasser to receive the 2012 FEBS/EMBO Women in Science Award

Research and Markets: Fungi: Biology and Applications, 2nd Edition

DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/5ff75e/fungi_biology_and) has announced the addition of John Wiley and Sons Ltd's new book "Fungi: Biology and Applications, 2nd Edition" to their offering.

Fungi: Biology and Applications, Second Edition provides a comprehensive treatment of fungi, covering biochemistry, genetics and the medical and economic significance of these organisms at introductory level. With no prior knowledge of the subject assumed, the opening chapters offer a broad overview of the basics of fungal biology, in particular the physiology and genetics of fungi and also a new chapter on the application of genomics to fungi.

Later chapters move on to include more detailed coverage of topics such as antibiotic and chemical commodities from fungi, new chapters on biotechnological use of fungal enzymes and fungal proteomics, and fungal diseases of humans, antifungal agents for use in human therapy and fungal pathogens of plants.

Key Topics Covered:

1 Introduction to Fungal Physiology

2 Fungal Genetics

3 Fungal Genomics

4 Fungal Genetics: A Post-Genomic Perspective

5 Fungal Fermentations Systems and Products

6 Pharmaceutical and Chemical Commodities from Fungi

7 Biotechnological Use of Fungal Enzymes

8 The Biotechnological Exploitation of Heterologous Protein Production in Fungi

9 Fungal Proteomics

10 Fungal Infections of Humans

11 Antifungal Agents for Use in Human Therapy

12 Fungal Pathogens of Plants

For more information visit http://www.researchandmarkets.com/research/5ff75e/fungi_biology_and

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Research and Markets: Fungi: Biology and Applications, 2nd Edition

Plants that shut out bacterial invaders

I have a soft-spot for plant biology. In my final year at university, having exhausted all of the bacteria-related biochemistry lectures, I took a bacteria-related lecture course with the plants department. It was a smaller department, and seemed a lot friendlier and nicer. Also the biscuits in the tea-room were cheaper.

So I do like to write about plants every now and again, and it isn’t a very difficult task because like every other multicellular organism on the planet, plants also suffer from bacterial infections. Unlike humans, they don’t have a blood stream to carry immune cells around, so they instead rely on bombarding bacteria with nasty chemicals, quickly killing off any parts of the plant that get infected and acquiring a kind of plant resistance to stop attacks occurring again. (The three links are to a mini-series on plant immunology on my old blog.)

However in plants, as in humans, prevention is much better than cure and so the plant has all sorts of mechanisms to stop bacteria getting inside and causing infections in the first place. Plants have openings in their leaves called stomata which are used to control water levels inside the plant cells. The stomata open up to release moisture and close to retain it. They aren’t massive holes, but they can be seen with a light microscope and identified fairly easily by your average 16 year old (I remember looking at them during my AS levels!)

A stoma! The two curved things surrounding it are the two cells that control the opening. The small oval-shaped middle bit is the stoma - a hole in the cells covering the leaf. Image credit below.

As stomata are basically a hole from the inside of the plant to the great bacteria-ridden outdoors, it is important that they remain well-regulated. Plants can recognise bits of bacteria and when they do they can change internal conditions to close up the stomata, bolting the doors to prevent bacteria getting in. By sensing parts of bacteria such as (say) flagella, proteins are activated that change the concentrations of salts inside the cells surrounding the stomata, and cause them loose their curved shape and come together, effectively closing off the opening.

When plants were infected with the bacterial strain of Pseudomonas syringae the stomata closed up within 1-2 hours of infection, which for a plant is fairly rapid. However around 3-4 hours later the stomata started opening up again, and it wasn’t due to a bacterial protein, but a plant one. The protein in question was LecRK-V.5 and plants without the gene for this protein developed fewer disease symptoms and contained lower levels of internal bacteria than the non-mutated wild-types. The figure below shows the wild-type leaves at the top, with more disease symptoms than the healthier mutants below.

Figure from ref. 1

As stomatal opening is only one factor in the antibacterial plant response, the researchers then explored whether LecRK-V.5 was affecting any other responses. The main one being the production of dangerous Reactive Oxygen Species (ROS) which are often produced to damage invading bacteria. Both wild-type and LecRK-knockout-mutant plants showed no difference in levels of ROS, LecRK-V.5 only seems to affect the stomata.

The point about ROS also gives a clue as to just why the plant chooses to activate this protein following infection, seemingly making it easier for bacteria to gain access to the interior. In the mutant plant cells, with no LecRK-V.5, high levels of ROS started building up in the cells surrounding the stomata. ROS are dangerous to any cell they come into contact with, so by dampening down the response to bacterial infection around 4 hours following entry, the plant might be saving itself from being damaged by its own immune response. If the infection is still spreading after four hours, it may be more prudent for the plant to abandon the dead tissue and try and salvage what’s left. Leaves are not desperately important to plants after all, they can always grow more!

Ref 1:Desclos-Theveniau, M., Arnaud, D., Huang, T., Lin, G., Chen, W., Lin, Y., & Zimmerli, L. (2012). The Arabidopsis Lectin Receptor Kinase LecRK-V.5 Represses Stomatal Immunity Induced by Pseudomonas syringae pv. tomato DC3000 PLoS Pathogens, 8 (2) DOI: 10.1371/journal.ppat.1002513

Ref 2: Nicaise, V., Roux, M., & Zipfel, C. (2009). Recent Advances in PAMP-Triggered Immunity against Bacteria: Pattern Recognition Receptors Watch over and Raise the Alarm PLANT PHYSIOLOGY, 150 (4), 1638-1647 DOI: 10.1104/pp.109.139709

Credit for image 1.

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Plants that shut out bacterial invaders

Students' get hands-on learning of human anatomy with use of cadavers

Posted: Wednesday, February 15, 2012 12:00 am | Updated: 7:25 pm, Tue Feb 14, 2012.

Instead of sticking strictly to textbooks and lectures, Sacramento State's health science students have tangible learning experiences working with real bodies in the Human Anatomy Learning Laboratory.

The laboratory, located in Humboldt Hall, has the capacity and is usually occupied by four donated bodies at a time. Three courses at Sac State incorporate use of the lab: Neuroanatomy, Advanced Anatomy and Human Anatomy for Physical Therapists - a course required for completion of the physical therapy doctorate program, which was established last year.

Biology professor Winston Lancaster is the primary anatomist in charge of the human anatomy facility. He assumed responsibility for the lab after the reassignment of professor Rose Leigh Vines, who began it around 1984. He said the lab provides a rare educational experience to Sac State's undergrads.

"My impression is that not many other schools in the California State University system have access to a lab like this," Lancaster said. "When I tell people what I do here, people generally react with surprise. Most people think, ‘It's just a CSU,' but we have access to resources that are usually reserved for medical schools ."

The opportunity is made possible through the UC Davis' Body Donation Program, which was formed in 1968 to assist medical education institutions in the region. The program distributes donated bodies to the university based on its status as a certified repository, which is required to ensure proper treatment of the bodies and can be revoked at any time.

UC Davis' Body Donation Program operates on unsolicited donations from volunteers in Northern California, according to its website. The program's website notes it has received 3,000 donated bodies thus far, and there are 4,000 living people registered as donors.

"All of the bodies are provided based on voluntary donations through UC Davis; no unidentified bodies are used in our labs," Lancaster said. "Also, all of the bodies go through a screening process that tests for specific diseases, and any bodies that test positive are not used."

UC Davis' program maintains privacy of all donors, which means no names or photos can be released. Because of this, students must place personal belongings, especially cellphones with cameras, into supplied lockers in Humboldt Hall.

"It's hard for some - cellphones are like a lifeline to most students," Lancaster said. "However, this is not usually a problem with the students taking these courses, as many of them are very serious about their studies. Usually, they are really excited about it, and respectful once in the lab."

Lancaster said students do not perform dissections, as neither the time, space nor funding is available for it. He said, however, occasionally he will bring in the hardest-working students to perform the pre-dissections that are presented in the lab.

Most of the time, students are given lab objectives which could involve identifying certain bones or muscles in isolated parts of the body. Students enrolled in one of the classes with access to the lab can come to supervised open lab periods to finish objectives, or further their studies.

"Working with these bodies allows students to better understand the individual variations of anatomy," Lancaster said. "We're just as different under the skin as we are outside of it, which is something that students are always surprised by. It takes looking at more than one body to figure that out."

Jeff Changaris, a graduate student who works with Lancaster, said he was introduced to working with donated bodies in 2006, and has preformed close to 500 dissections since then.

"I can honestly say the experience has changed my life," Changaris said. "We all have this image of what we think the inside of the body would look like, but the body is definitely more than the sum of its parts. Everything within the body is connected, even if it's just barely."

Changaris now manages the donated bodies program at American River College, which has a smaller scale anatomy lab than Sac State's. He gives dissection demonstrations at the college primarily to the school's nursing students.

"When students are given their first exposure, you just don't know how any individual is going to handle that information until it happens," Changaris said. "When I do demonstrations, I let people stand in the back and inch slowly forward."

Rebekah Dobish, senior kinesiology major, said she was both nervous and excited upon entering the lab for the first time, but has learned a great deal from the exposure and has since returned to help Lancaster with dissections.

"You hear the stories about the smell of formaldehyde and it being disgusting, but professor Lancaster makes it very comfortable and professional environment so that apprehension goes away quickly," Dobish said. "Overall, it's just a great experience for biology and kinesiology majors alike."

Lancaster said with an estimated 5,000 named parts of the human body, studying anatomy can be difficult. On top of that, it requires first-hand experience - like what students get in the anatomy lab - to achieve a comprehensive understanding and appreciation of the human body.

"There are many subtle things you can't get from a textbook, but you deal with daily as a practicing professional," Lancaster said. "It takes actual seeing, touching and moving things aside to truly understand the fabric of anatomy."

Brett Johnson can be reached at news@statehornet.com.

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Students' get hands-on learning of human anatomy with use of cadavers