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Cenergy Nutrition Appoints COO for Production and Branding of Supplement Line

Posted on March 1, 2012 by ev1

NEW YORK, Feb. 29, 2012 /PRNewswire/ --Creative Edge Nutrition, Inc. ("Cenergy"), the operating subsidiary of Laufer Bridge Enterprises, Inc. (OTC:LBGE.PK - News), announced the appointment of Mr. Bill Chaaban as the new ChiefOperating Officer (COO), and to the Board of Directors of Cenergy Nutrition.

Bill Chaaban, B.Comm., JD, LL.B., LL.M.is a licensed attorney in theUSA and Canada, and will advise themanagement teamregarding daily operational and regulatory affairs ashe hasintimate knowledgeregarding the manufacture, wholesale and retail distribution of nutritional supplements.He operates one of the few privately owned companies that is vertically integrated from the manufacturing to retail consumer level.Mr. Chaaban hastwenty five years of industry experience, and will oversee the manufacturing and branding of the Cenergy supplement product lines.

Mr. Chaaban is also the founder of http://www.Fitnessone.com, which is a leading online retailer, and will be involved in the day to day operations, as Mr. Chaaban's strategic and industry insightwill benefit in the development of the Cenergy brand.

International Distribution

Mr. Chaabanwill also aid in developing the distribution of our brand in foreign markets as hisknowledgeof foreign laws and regulations pertaining to sales and marketing of nutritional supplementswill befundamental to the growth of Cenergy Nutrition'sbusiness abroad.

Keith Thomas, the CEO of Cenergy Nutrition commented, "The appointment of Mr. Chaaban to the position of COO now positions Cenergy Nutrition to prepare for its upcoming launch and distribution of its nutritional supplement lines. We are very excited as the company is now putting together a team with a wealth of experience in the marketing and branding of nutritional supplements, and now sets the stage for Cenergy Nutrition to embark on its long awaited world-wide launch."

In addition, the Company has retained the New York based public relations firm South Street Media, Inc (www.southstreetmedia.com) to assist the company in shareholder and media communications as the company enters the production and distribution phase of its business model.

About Creative Edge Nutrition, Inc.

Laufer Bridge Enterprises, Inc., through its operating wholly subsidiary Creative Edge Nutrition, Inc., is a nutrition company engaged in the development of nutracueticals. They will offer a broad spectrum of capsules, tablets, and powders, as well as science based products in three principal categories. These categories are weight management, nutrition challenges, energy and fitness. The Company's objective is to successfully market, distribute nutritional products, and continue to develop innovative supplements. http://www.CenergyNutrition.com

To request an investor packet onCenergy Nutritionregister online at http://www.wallstreetnewscast.com/request/lbge.html

New treatment using inhaled interferon may improve lung function in pulmonary fibrosis

Posted on March 1, 2012 by ev1

Public release date: 29-Feb-2012 [ | E-mail | Share ]

Contact: Cathia Falvey cfalvey@liebertpub.com 914-740-2100 Mary Ann Liebert, Inc./Genetic Engineering News

New Rochelle -- Inhaled interferon-gamma may be an effective treatment for idiopathic pulmonary fibrosis (IPF), a chronic and progressive form of lung disease caused by excessive formation of fibrotic, or scar tissue, in the lungs, according to an article published in Journal of Aerosol Medicine and Pulmonary Drug Delivery (http://www.liebertpub.com/jamp), a peer-reviewed journal from Mary Ann Liebert, Inc. (http://www.liebertpub.com) The article on inhaled interferon-gamma (http://online.liebertpub.com/doi/abs/10.1089/jamp.2011.0919) is available free online at the Journal of Aerosol Medicine and Pulmonary Drug Delivery website.

Normally, systemic delivery of interferon-gamma can cause substantial side effects; however, delivery of aerosolized interferon-gamma directly into the lungs was shown to be safe and was associated with significantly reduced levels of profibrotic regulatory proteins. Keith Diaz, MD, Shibu Skaria, MD, Keith Harris, MD, Mario Solomita, DO, Stephanie Lau, MD, Kristy Bauer, MD, Gerald Smaldone, MD, PhD, and Rany Condos, MD, State University of New York, Stony Brook and New York University School of Medicine, NYC, show that inhalation of interferon-gamma in aerosol form three times a week for at least 80 weeks was well-tolerated by patients, with no systemic side effects.

The authors verified the presence of the drug in the material collected on lung washes and documented no change in the level of interferon-gamma in the blood during the treatment period. The report shows the results of pulmonary function tests, including forced vital capacity (FVC) and total lung capacity (TLC), and the effects of treatment on a six-minute walk test in the article entitled "Delivery and Safety of Inhaled Interferon-gamma in Idiopathic Pulmonary Fibrosis." (http://online.liebertpub.com/doi/abs/10.1089/jamp.2011.0919)

"There is no treatment for Idiopathic Pulmonary Fibrosis, a disease usually fatal within 3-5 years," says Gerald C. Smaldone, MD, PhD, Editor-in-Chief of the Journal and a coauthor of this article, and Professor and Chief, Division of Pulmonary and Critical Care Medicine at SUNY-Stony Brook. "The scientific community expected the injected form of interferon-gamma to help, but those studies failed. We have shown that inhaled interferon is safe with very high levels in the lungs. Now is the time to repeat the clinical trials with the inhaled form of this therapy."

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About the Journal

Journal of Aerosol Medicine and Pulmonary Drug Delivery (http://www.liebertpub.com/jamp) is an authoritative peer-reviewed journal published bimonthly in print and online. It is the Official Publication of the International Society for Aerosols in Medicine (www.isam.org). The Journal is the only authoritative publication delivering innovative articles on the health effects of inhaled aerosols and delivery of drugs through the pulmonary system. Topics covered include airway reactivity and asthma treatment, inhalation of particles and gases in the respiratory tract, toxic effects of inhaled agents, and aerosols as tools for studying basic physiologic phenomena. Complete tables of content and a sample issue may be viewed on the Journal of Aerosol Medicine and Pulmonary Drug Delivery (http://www.liebertpub.com/jamp) website.

About the Company

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New treatment using inhaled interferon may improve lung function in pulmonary fibrosis

NIH Launches Genetic Testing Registry

Posted on March 1, 2012 by ev1

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) The National Institutes of Health has launched a new web resource aimed at providing consumers and healthcare providers with information about all of the genetic tests that are currently on the market.

The Genetic Testing Registry, unveiled today international Rare Disease Day was developed to serve as an encyclopedia of the genetic tests that currently exist for around 2,500 genetic diseases, one which will be updated as new tests and applications come on the market.

The goal was to create a resource that would help healthcare providers and consumers sort through information about the available tests, because most do not require premarket review by the US Food and Drug Administration.

The GTR entries will cover information on the purpose of the test, its limitations, the name and location of the providers, whether it is for clinical or research use, what methods are used, and how the results are measured. NIH will not verify the content of the entries provided by the testing providers, but it will require that they agree to a code of conduct for accuracy that will enable NIH to require submitters to correct inaccuracies or to remove such information from the resource.

On top of the basic information, the voluntary GTR will provide details about a test's analytic validity, clinical validity, and clinical utility.

"I'm delighted that NIH has created this powerful, new tool. It is a tremendous resource for all who are struggling to make sense of the complex world of genetic testing," NIH Director Francis Collins said in a statement.

"This registry will help a lot of people from healthcare professionals looking for answers to their patients' diseases to researchers seeking to identify gaps in scientific knowledge."

"Our new registry features a versatile search interface that allows users to search by tests, conditions, genes, genetic mutations, and laboratories," said GTR Director Wendy Rubinstein. "What's more, we designed this tool to serve as a portal to other medical genetics information, with context-specific links to practice guidelines and a variety of genetic, scientific and literature resources available through the National Library of Medicine at NIH."

The registry was developed by the National Center for Biotechnology Information, with input from a range of stakeholders, including testing labs, healthcare providers, patients, and researchers, through a public comment period and public meetings.

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NIH Launches Genetic Testing Registry

Lafayette’s ‘R.U.R’ deals with robots, role of technology

Posted on March 1, 2012 by ev1

Lafayette College theater director Michael O'Neill has never seen the classic Czech play "R.U.R," but after teaching it in his theater classes for years, he became intrigued by the relevance of its premise.

So after reading many translations of the play about robots and a mechanized world where people show no emotions, O'Neill decided to write his own translation and produce it at the college. The play opened Wednesday and continues through Saturday at the Williams arts center.

"I made a lot of cuts," O'Neill says. "In those days, they tended to be awfully talky."

"R.U.R." or "Rossum's Universal Robots" was written in 1920 by Karel Capek. It was a response to the death and destruction he had witnessed during World War I and the emotional dislocation and upheavals of the 1917 Communist revolution in Russia.

The play was written as an expressionistic journey into genetic engineering on a mass scale, O'Neill says. It predicted a mechanized world where people have no emotional connections and where workers have lost their human rights. The play takes place in a factory that makes Robots that can think for themselves and can be mistaken for humans.

"I thought that the play had a lot to say about today and our interest in human cloning and our dependence on technology," O'Neill says. "I was concerned about our growing dependence on our cell phones and our computers and the increasing mechanization of everyday life. I also thought that that this play was particularly relevant to Lafayette, which has such a big engineering program."

The play was the first to introduce the word robot to the English language.

"Actually the word robot means 'worker' in Czech, and the Robots in our production look less like Hollywood robots than Soviet workers from the 1920s," O'Neill says. Costume designer Locklyn Brooks has created gray and monochrome outfits that make the Robots look less like machines and more like people, he says.

O'Neill says the play is not so much science fiction as a social satire with a utopian vision.

"This is actually a very traditional play, and despite the presence of the Robots, its main theme is that the human race needs love to be able to survive," he says.

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Lafayette's 'R.U.R' deals with robots, role of technology

Roche´s MagNA Pure LC 2.0 System for Monitoring DNA in Therapeutic Proteins and Monoclonal Antibody Drugs

Posted on March 1, 2012 by ev1

PENZBERG, Germany, February 29, 2012 /PRNewswire/ --

To ensure product safety, clearance of host-cell DNA is essential when manufacturing therapeutic proteins and monoclonal antibody (mAB) drugs. Using the MagNA Pure LC 2.0 System from Roche, scientists have developed and validated an automated process for monitoring clearance of Chinese hamster ovary (CHO) cell DNA during the capture and polishing steps when processing therapeutic proteins and mAB drugs (1).

Automated DNA monitoring during manufacturing eliminates the need to perform manual DNA extraction that can create analytics bottlenecks during process development and routine testing. Automated DNA isolation using Roche's MagNA Pure LC 2.0 System results in high DNA recovery rates and subsequent highly sensitive qPCR with the LightCycler 480 Real-Time PCR Instrument. MagNA Pure LC DNA purification eliminates: (a) Manual dilution of high-protein and high-DNA loads; (b) Manual acidic sample neutralization; and (c) Manual carrier RNA addition.

Roche has produced validation data comparing DNA extraction of manufacturing samples spiked with CHO DNA using Roche's MagNA Pure LC 2.0 System and competitive instrumentation. In contrast to the other instrumentation, the MagNA Pure LC 2.0 System did not require manual sample preprocessing, additional proteinase K pretreatment, sample neutralization and dilution, or carrier RNA. The MagNA Pure LC DNA System isolation was shown to require less hands-on time for higher performance than the competitive instrumentation. These findings indicate that MagNA Pure LC 2.0 System automated sample preparation can be productively used to reduce analytics bottlenecks during in-process development and quality control of therapeutic proteins and mAB drugs.

About Roche

Headquartered in Basel, Switzerland, Roche is a leader in research-focused healthcare with combined strengths in pharmaceuticals and diagnostics. Roche is the world's largest biotech company with truly differentiated medicines in oncology, virology, inflammation, metabolism and CNS. Roche is also the world leader in in-vitro diagnostics, tissue-based cancer diagnostics and a pioneer in diabetes management. Roche's personalized healthcare strategy aims at providing medicines and diagnostic tools that enable tangible improvements in the health, quality of life and survival of patients. In 2011, Roche had over 80,000 employees worldwide and invested over 8 billion Swiss francs in R&D. The Group posted sales of 42.5 billion Swiss francs. Genentech, United States, is a wholly owned member of the Roche Group. Roche has a majority stake in Chugai Pharmaceutical, Japan. For more information: http://www.roche.com.

All trademarks used or mentioned in this release are protected by law.

MAGNA PURE und LIGHTCYCLER are trademarks of Roche.

All other product names and trademarks are the property of their respective owners.

For further information please contact:

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Roche´s MagNA Pure LC 2.0 System for Monitoring DNA in Therapeutic Proteins and Monoclonal Antibody Drugs

DNA results in Stephenson murder case delivered to Boone County Sheriff's Office for examination

Posted on March 1, 2012 by ev1

FLORENCE, Ky. - 9 News has learned that the much-anticipated results of DNA testing in the 9-month-old double murder case of an N.Ky. couple has been sent from the lab to the Boone County Sheriffs Office for examining.

Bill and Peggy Stephenson, both 74, of Florence, were found brutally murdered in May 2010 in their Florence condo by their daughter's husband.

Detectives and members of the Stephensons' family have been anxious for these results, which they hope will lead to a break in the case that has devastated the Florence community.

This is the first of three rounds of DNA testing that will be done. Investigators believe this round will most likely lead to a killer if they are able to find anything.

The Stephensons' daughter, Beth Victor, tells 9 News she is relieved to now have this evidence back from the lab, but only "cautiously optimistic" it will help bring answers after such a long and painful wait.

"It's been terrible on our family. It's just been horrible," said Victor.

The Stephensons were pillars of their community. They ran a truck stop ministry at Travel Centers of America in Florence. Bill led a service there every Sunday, and Peggy played the organ at the couple's Florence church. Why someone would kill them has baffled detectives for nine months.

The conversation that had to happen between Victor and her husband the day they were killed was more than Victor could talk about.

Victor says she and her siblings have met almost weekly, sometimes with detectives, to talk and support each other.

"I will say one thing, it's drawn us closer as a family, but I hate it's taken this to make us closer," said Victor.

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DNA results in Stephenson murder case delivered to Boone County Sheriff's Office for examination

DNA in N.Ky. double murder delivered

Posted on March 1, 2012 by ev1

Bill and Peggy Stephenson, both 74, of Florence, were found brutally murdered in May 2010 in their Florence condo.

Detectives and members of the Stephensons' family have been anxious for these results, which they hope will lead to a break in the case that has devastated the Florence community.

This is the first of three rounds of DNA testing that will be done. Investigators believe this round will most likely lead to a killer if they are able to find anything.

The Stephensons' daughter, Beth Victor, tells 9 News she is relieved to now have this evidence back from the lab, but is only "cautiously optimistic" it will help bring answers after such a long and painful wait.

"It's been terrible on our family. It's just been horrible," said Victor.

Victor's husband found the couple dead in their home. The conversation that had to happen between Victor and her husband that day was more than Victor could talk about.

Victor says she and her siblings have met almost weekly, sometimes with detectives, to talk and support each other.

"I will say one thing, it's drawn us closer as a family, but I hate it's taken this to make us closer," said Victor.

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DNA in N.Ky. double murder delivered

New light shed on cause of lung injury in severe flu

Posted on March 1, 2012 by ev1

Public release date: 29-Feb-2012 [ | E-mail | Share ]

Contact: Cody Mooneyhan cmooneyhan@faseb.org 301-634-7104 Federation of American Societies for Experimental Biology

While some scientists report engineering a super virulent strain of the H5N1 influenza virus, which could potentially wipe out a significant percentage of the human population, another group of researchers from the United Kingdom now reports a discovery that may one day help mitigate the deadly effects of all flu strains. This report, appearing in the March 2012 print issue of the Journal of Leukocyte Biology, describes findings that may help prevent deaths from severe flu outbreaks, especially from seemingly healthy young people. Specifically, the researchers found that immune cells called, "natural killer T cells," may reduce the overwhelming numbers of another type of immune cell, called "inflammatory monocytes," which when present in large numbers, lead to lung injury at the end stage of severe flu infection.

"We hope this study will ultimately benefit individualsespecially the youngwho succumb to a severe form of flu infection," said Ling-Pei Ho, M.D., Ph.D., the researcher who led the work from the MRC Human Immunology Unit, Oxford University in Oxford, United Kingdom. "The study highlights a key immune process that occurs in severe flu infection, and provides a platform for a new approach and further research in this area."

To make their discovery, scientists infected three groups of mice with H1N1 flu virus. (Note: this is NOT the H5N1 flu virus that has been at the center of recent controversy.) The first group included normal mice; the second group was devoid of natural killer T cells, and the third was given a treatment that specifically activated natural killer T cells. Researchers observed the outcome of flu infection and found that the mice without natural killer T cells did worst, and those with activated killer T cells did best. Mice that lacked natural killer T cells had increased amounts of monocytes in the lungs, and severe lung injury similar to those seen in Spanish flu and lethal swine flu. Using highly-sensitive fluorescent antibody technology, this study was one of the first to document the sequential changes in innate immune response in the lungs during severe flu infection. These findings essentially provide a "road map" of the chronological changes in the lungs during severe flu infection.

"Despite affecting practically everyone, the flu may be one of the most underestimated viruses in terms of its devastating potential," said John Wherry, Ph.D., Deputy Editor of the Journal of Leukocyte Biology. "As the H5N1 research shows, it is quite possible for the virus to mutate or be bioengineered into a form that could wipe most of us out. What most people don't realize is that the severe illness from these flu strains is caused by both the virus and an overaggressive or inappropriate immune response. Research like this, however, offers hope that we'll be able to find more universal ways improve the effectiveness of immunity and combat the severe strains of the flu."

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The Journal of Leukocyte Biology (http://www.jleukbio.org) publishes peer-reviewed manuscripts on original investigatins focusing on the cellular and molecular biology of leukocytes and on the origins, the developmental biology, biochemistry and functions of granulocytes, lymphocytes, mononuclear phagocytes and other cells involved in host defense and inflammation. The Journal of Leukocyte Biology is published by the Society for Leukocyte Biology.

Details: Wai Ling Kok, Laura Denney, Kambez Benam, Suzanne Cole, Colin Clelland, Andrew J. McMichael, and Ling-Pei Ho. Invariant NKT cells reduce accumulation of inflammatory monocytes in the lungs and decrease immune-pathology during severe influenza A virus infection. J. Leuk. Biol. March 2012; 91:357-368; doi:10.1189/jlb.0411184; http://www.jleukbio.org/content/91/3/357.abstract

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New light shed on cause of lung injury in severe flu

Pecan weevil biology, management and control strategies

Posted on March 1, 2012 by ev1

Public release date: 29-Feb-2012 [ | E-mail | Share ]

Contact: Richard Levine rlevine@entsoc.org 301-731-4535 Entomological Society of America

The pecan weevil, Curculio caryae (Horn), is a major pest of pecans throughout the southeastern United States, as well as portions of Texas and Oklahoma.

In "Biology and Management of the Pecan Weevil (Coleoptera: Curculionidae)," (http://bit.ly/xrqS3d) a new article appearing in the Journal of Integrated Pest Management, scientists from Oklahoma State University and Texas A&M University describe the biology, life stages, crop injury, monitoring approaches, and primary control strategies currently used for pecan weevil in pecan.

Aimed at pecan growers extension personnel using integrated pest management (IPM) strategies, the authors describe monitoring techniques using limb Jarring, tree bands, knockdown sprays, pyramid traps, circle traps, and infestation records.

Other management considerations, such as biological control and livsestock grazing are also discussed.

Finally, suggested economic thresholds are extrapolated from several sources and the utility of current monitoring information is presented to aid in management and quarantine decisions.

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The full article is available for free at http://bit.ly/xrqS3d.

The Journal of Integrated Pest Management (http://www.entsoc.org/Pubs/Periodicals/jipm) is a peer-reviewed, open-access, extension journal covering the field of integrated pest management. It is published by the Entomological Society of America (http://www.entsoc.org), the largest organization in the world serving the professional and scientific needs of entomologists and people in related disciplines.

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Pecan weevil biology, management and control strategies

Research and Markets: The AH Receptor in Biology and Toxicology

Posted on March 1, 2012 by ev1

DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/30dc32/the_ah_receptor_in) has announced the addition of John Wiley and Sons Ltd's new book "The AH Receptor in Biology and Toxicology" to their offering.

This book provides a thorough and up-to-date overview of the aryl hydrocarbon receptor (AHR) and its unique dual role in toxicology and biology. The coverage includes epigenetic mechanisms, gene expression, reproductive and developmental toxicity, signal transduction, and transgenic animal models. Featuring an internationally recognized team of authors at the forefront of AHR research, this resource provides a comprehensive reference for readers interested in understanding the full spectrum of AHR, from basic concepts, toxicology analysis, and models to polymorphism and related diseases.

Key Topics Covered:

AHR as a ligand-activated transcription factor.

AHR as a mediator of xenobiotic toxicities: dioxins as a key example.

AHR as a physiological regulator.

Author: Raimo Pohjanvirta.

For more information visit http://www.researchandmarkets.com/research/30dc32/the_ah_receptor_in

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Research and Markets: The AH Receptor in Biology and Toxicology

Nature Commentary investigates synthetic-biology disaster

Posted on March 1, 2012 by ev1

Without key research into these risks and appropriate federal oversight, certain synthetic organisms might survive and flourish in natural environments, wreaking havoc on local ecosystems, according to a new Commentary piece in the journal Nature ("Four Steps to Stop a Synthetic-Biology Disaster," March 1).

The article -- written by Genya V. Dana, Todd Kuiken and David Rejeski of the Synthetic Biology Project at the Woodrow Wilson International Center for Scholars and Allison A. Snow of Ohio State University -- highlights the need to proactively address environmental risks so that the potential benefits of synthetic biology can be realized.

"No one yet understands the risks that synthetic organisms pose to the environment, what kinds of information are needed to support rigorous assessments, or who should collect such data," the authors write.

And while similar questions were raised about genetically modified crops, the products of synthetic biology "will be altered in more sophisticated and fundamental ways (such as elimination of metabolic pathways), making them potentially more difficult to regulate, manage and monitor."

The authors say it is imperative to start the research ahead of expected advancements in the field. "Synthetic biology has already moved out of the lab, propelled by significant public and private investments in organisms modified to produce chemicals, medicines and biofuels," they write. The global market for synthetic biology is expected to increase to $10.8 billion over the next four years.

The authors propose four areas that risk researchers, scientists, regulators and other key stakeholders should focus on in the near term: how the physiology of synthetic organisms is different from naturally occurring organisms; how "escaped" synthetic organisms might affect the environment; how synthetic organisms might evolve in the natural environment; and consequences of synthetic organisms exchanging genetic materials with naturally occurring organisms.

The authors caution that this research will take time, and emphasize that such work should be integrated into the larger synthetic biology research agenda. "Public agencies must link basic and environmental risk research by co-funding projects and requiring grant recipients to work with environmental scientists from the start," the article says.

The Wilson Center has already been encouraging dialogue between synthetic biologists and ecologists on the potential risks of synthetic biology. In July 2011, the Center held a workshop focused on bringing together engineers and ecologists to help identify key research areas needed to support future ecological risk assessments for synthetic biology applications. While this work continues, the authors stress the need for much more interdisciplinary research and discussion.

The call for research funding comes as federal agencies are determining how best to respond to a 2010 report on synthetic biology from the Presidential Commission for the Study of Bioethical Issues. The Wilson Center in February launched a scorecard to track the federal and non-federal response to the commission's recommendations. The scorecard can be found here: http://www.synbioproject.org/scorecard/

More information: The Nature Commentary can be found online at http://www.nature. 483029a.html

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Nature Commentary investigates synthetic-biology disaster

Commentary in Nature: How do you stop a synthetic-biology disaster?

Posted on March 1, 2012 by ev1

Public release date: 29-Feb-2012 [ | E-mail | Share ]

Contact: Aaron Lovell aaron.lovell@wilsoncenter.org 202-691-4320 Woodrow Wilson International Center for Scholars/Science and Technology Innovation Program

Experts say at least $20 million to $30 million in government research is needed over the next decade to adequately identify and address the possible ecological risks of synthetic biology, an emerging area of research focused on the design and construction of new biological parts and systems, or modification of existing ones, to create new applications in areas ranging from energy to chemicals and pharmaceuticals.

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Commentary in Nature: How do you stop a synthetic-biology disaster?

GenScript Was the Most Frequently Referred Biology Contract Research Organization by Peer-Reviewed Journal Articles in …

Posted on March 1, 2012 by ev1

PISCATAWAY, N.J., Feb 29, 2012 /PRNewswire-Asia/ --GenScript USA Inc., an internationally recognized biology contract research organization (CRO), became the most frequently referred biology CRO in the world by peer-reviewed journal articles in the year 2011.

Ever since its inceptionin 2002, GenScript has been consistently providing biological researchers with unmatched quality workmanship at affordable prices. In merely 9 years, GenScript has grown into a world leading CRO with over 1,000 employees. In 2011, more than 2,300 journal articles referred GenScript's services and products - making GenScript the most frequently referred CRO in the world!

"I am truly grateful to the trust and support of our clients. Their successes are the ultimate driving force for us," says Frank Zhang, the CEO and co-founder of GenScript. "I am very proud that our company has been recognized as an out-sourcing partner by more and more world-leading researchers."

In the last decade, over 1,100 CRO companies were established in the world, but few have maintained continuous growth. "The key to our robust and organic growth is the courage and dedication in pioneering innovative technologies. As always, we will continue to invest inthe development of cutting-edge enabling technologies. Our customers can count on us to deliver the faster, more reliable and cost-effective services and products than our competitors," commented Frank.

About GenScriptUSA, Inc. Headquartered in Piscataway, New Jersey, GenScript USA Inc. is a global contract research organization leader, with operations in USA, Japan, and China. As a market-driven and customer-focused company, GenScript provides comprehensive services for biological research and early-phase drug discovery, such as bio-reagents, assay development & screening, antibody drug development and animal model services. The bio-reagents services include custom gene synthesis and molecular biology, custom protein expression and purification, custom peptide synthesis, antibody production, and custom cell line development.

For further information, please contact:

Sally Wang Executive Vice President GENSCRIPT USA Inc. 1-(732) 885-9188 http://www.genscript.com

“Winning at Aging” Provides Comprehensive Game Plan for the Second Half of Your Life

Posted on March 1, 2012 by ev1

New Book Presents Evidence-Based Strategies for Living Better and Longer. Author Dr. John Kalb presents latest research from neuroscience, anti-aging medicine, psychology, and spirituality for creating a healthy aging lifestyle.

(PRWEB) February 29, 2012

In his new book, Winning at Aging: Your Game Plan for Healthy Living, Dr. John Kalb asks the provocative question: How about you? What do you want to be capable of doing in your 50s, 80s, and beyond? Can you imagine yourself accomplishing something like they did? Do you have a game plan for healthy aging?

Winning at Aging goes where few health books have gone before by providing readers with more than just a new diet or exercise program. Dr. Kalb takes the position that a bigger vision of our human predicament is needed, one that looks at both the angels of our higher nature and the darker side of our fears of inadequacy. Dr. Kalb explains how we need inspiration and purpose to live a fulfilling and truly healthy life. To combat self-sabotaging of our aim to create a more healthy and fulfilling life, he proposes what he calls the Magnificent Seven Dimensions of Successful Aging:

Starting from this bigger vision of the whole person in the midst of a complex world, Dr. Kalb brings into play cutting edge research from neuroscience, anti-aging medicine, and psychology. He does this in a style that deeply engages the reader through his clarity of expression, humor, and sage advice. He provides the ultimate game plan to:

Winning at Aging is being hailed as an important new book for any one who wants to live a

more healthy and vibrant life. Harold Bloomfield, M.D., author of the bestselling Making Peace

with Your Past, calls the book a veritable treasure trove of powerful, practical strategies and advice for youthing and aging gracefully. While bestselling author Dr. Joe Marshalla says that this book is the most practical, thorough, comprehensive, accurate, down-to-earth, compassionate, and fun-loving guide to what we all must ultimately face.

Dr. Kalb encourages everyone to begin their journey into wellness: Winning at aging starts now, regardless of your age. Its always the right time to find a new vision and live your dreams. Be curious, be grateful, be active, be wise, be nourished, and give. And win at aging!

To receive a review copy or for media interviews, contact: Steve Scholl, Confluence Books

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“Winning at Aging” Provides Comprehensive Game Plan for the Second Half of Your Life

Anatomy of a coverup

Posted on March 1, 2012 by Danzig

The special investigative squad of the Tokyo District Public Prosecutors Office is investigating the alleged coverup of massive investment losses by Olympus Corp. following the arrests in mid-February of three of its former executives and four former securities firms employees.

It is hoped that investigators will put together a total picture of the scandal by going beyond what the third-party investigatory committee commissioned by Olympus uncovered.

In its report made public in early December, the third-party committee said Olympus began making speculative investments with financial assets in 1985 and that unrealized losses reached nearly 100 billion in the last part of the 1990s.

As of 2003, it had hidden 117.7 billion in losses by employing an elaborate loss separation scheme. The panel said that if the costs paid by Olympus to manage the schemes are taken into account, losses would amount to 134.8 billion.

The former Olympus executives taken into custody are former Chairman and President Tsuyoshi Kikukawa, former auditor Hideo Yamada and former Executive Vice President Hisashi Mori. The four former securities firms employees are suspected of having advised the Olympus management on the loss coverup scheme.

Olympus enjoys a 70 percent share of the global market for endoscopes and can be proud of its technological prowess. Despite the scandal, it managed to maintain its listing on the Tokyo Stock Exchange. But because it is a famous Japanese manufacturer, its responsibility is all the more greater. It should realize that the scandal has not only tarnished its image but also caused suspicion over Japan's corporate governance.

The public prosecutors office decided to place criminal responsibility not only on the former executives but also on the company itself. Olympus is facing a potential fine of up to 700 million. It is also facing shareholder lawsuits.

The company's wrongdoing came to light on Oct. 14 after it abruptly fired then President and CEO Michael C. Woodford, who is reported to have pointed out highly unusual advisory fees the company paid in acquiring a British medical equipment maker. It is suspected that Olympus inflated costs for the acquisition of the British firm and three other Japanese companies to mask its investment losses.

It is hoped that investigators will trace in detail the methods Olympus employed to hide its losses and falsify its financial reports.

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Anatomy of a coverup

Snooki & Jionni: Anatomy of a Jersey Shore Romance…and Pregnancy!

Posted on March 1, 2012 by Danzig

In the first season of the hit MTV show back in 2009, we saw her hit on The Situation and Ronnie. She also had a nice beach makeout session with Russ, a guy she met at a bar who turned out to be a spy for JWoww's boyfriend.

With that in mind, let's take a little trip down memory lane...

April 2010: Snooki calls it quits with boyfriend Emillio Masella just two months after meeting on Facebook.

August 2010: A romance with Jeff Miranda doesn't last long, but he tries winning her back by asking her to marry him on the cover of a magazine. She rejects him by tweeting that she's single.

September 2010: TMI! Snookers reveals on the show that she and Vinny hooked up, gushing that he was so well-endowed, it was like "putting a watermelon in a pinhole."

October 2010: Snooki and Jionni start dating. She tweets a pic of breakfast Jionni made for herpickle pancakes! No wonder she tweeted that she will "marry him" one day.

January 2011: During an appearance on The Tonight Show, Snook reveals Jionni coaches youth wrestling and is in school to become a gym teacher.

August 4, 2011: Season four of Jersey Shore kicks off with The Situation claiming he and Snookers hooked up when they were shooting in Italy. She insists "nothing happened."

PHOTOS: Remember when Jersey Shore first hit Hollywood?

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Snooki & Jionni: Anatomy of a Jersey Shore Romance...and Pregnancy!

Cold air bad for heart patients

Posted on February 29, 2012 by ev1

Washington, Feb 29 (IANS) Cold air is bad for heart patients, especially when they are undertaking physical activity, because they are unable to cope with the higher oxygen demanded by the body.

"This study can help us understand why cold air is such a trigger for coronary events," said Lawrence I. Sinoway, professor of medicine and director of the Heart and Vascular Institute, Penn State College of Medicine.

Breathing cold air during exercise can cause uneven oxygen distribution throughout the heart. But a healthy body generally corrects for this problem and redistributes blood flow, making sure the heart continues to function properly.

In people with heart problems, such as coronary artery disease, this may not be the case, said Sinoway, the Journal of Applied Physiology and American Journal of Physiology, Heart and Circulatory Physiology report.

"If you are doing some type of isometric work and you're breathing cold air, your heart is doing more work -- it's consuming more oxygen," said Sinoway, according to Penn State statement.

Isometric work includes such activities as shovelling snow and carrying a briefcase or laptop bag. The heart works harder when exerted in cold temperatures and the number of deaths due to cardiac arrest peaks during the winter.

"There are two different things going on here -- demand and supply," said Matthew D. Muller, postdoctoral fellow at the Heart and Vascular Institute, Penn State College of Medicine.

"We thought that oxygen demand in the heart would be higher with cold-air breathing and we also thought that oxygen supply would be a little bit impaired. And that's generally what we found," added Muller.

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Cold air bad for heart patients

Many Gaps in Fast-Food Nutrition Information

Posted on February 29, 2012 by ev1

TUESDAY, Feb. 28 (HealthDay News) -- Even when fast-food restaurants list calorie counts for menu items, diners may still have a hard time using the information to make healthy meal choices, researchers report.

In the study, the scientists examined the calorie listings for 200 food items on menu boards from 12 restaurant chains in the New York City neighborhood of Harlem.

Too often, calorie counts were listed for combo meals or meals intended to serve multiple people, or had wide ranges in what the calorie count might be.

For example, a bucket of chicken was listed as having 3,240 to 12,360 calories, but the menu board did not provide enough information for consumers to determine the number of pieces of chicken in a serving size.

A listing for a sandwich combo meal said it ranged from 500 to 2,080 calories. However, no information was provided on how to order within the lower range of this menu item.

Under federal law, restaurants with 20 or more locations must provide calorie data and additional nutritional information for menu items and self-serve foods. Although the calorie information complied with U.S. labeling rules, consumers may have a tough time making sense of much of it, the study found.

"Menu postings for individual servings are easily understood, but complex math skills are needed to interpret meals designed to serve more than one person," wrote study author Elizabeth Gross Cohn, an assistant professor at the Columbia University School of Nursing, and colleagues. "In some items, calories doubled depending on flavor, and the calorie posting did not give enough information to make healthier selections."

Researchers suggested that calorie listings should do more than merely comply, but take into account what level of "math literacy" is needed to make use of the information. In a revised system, a breakfast sandwich, for example, would be listed as, "Egg with ham/bacon/sausage: 350/550/750," so consumers could know exactly how many calories various options would add.

"In low-income communities with a high density of chain restaurants, and where educational attainment of consumers may be low, simplifying calorie postings and minimizing the math required to calculate calories would increase menu-board utility," the researchers wrote.

The study was published online Feb. 16 in the Journal of Urban Health.

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Many Gaps in Fast-Food Nutrition Information

Practical Nutrition: Benefits of beans

Posted on February 29, 2012 by ev1

By: MARY-JO SAWYER | Special Correspondent Published: February 29, 2012 Updated: February 29, 2012 - 12:00 AM

Beans, beans, the magical fruit! The more you eat, the more you can improve your nutrition, increase protein, lower your cholesterol and control your blood sugar. I bet you were expecting another description, but whatever their reputation, dried beans and peas are inexpensive nutrition dynamos.

Beans and peas are really vegetables and include kidney, pinto, black and lima beans, chickpeas, split peas, black-eyed peas and lentils. They come frozen, canned or dried.

They're rich in iron, zinc, folate and potassium, nutrients often low in many American diets. White beans, black-eyed peas, black beans and lentils are good sources of iron.

Dried beans and peas are protein foods, too. A half cup cooked is equal to 2 ounces of meat. Save money on your grocery bill by having vegetarian entrees, such as vegetable chili or beans and rice, several times a week. Add protein to your meals with refried beans, or toss a few into your salads or meat chili.

A half cup of cooked beans contains 6 to 8 grams of fiber, both soluble and insoluble. Insoluble fiber promotes healthy digestion, and may be linked to reducing colon cancer. The soluble fiber helps reduce high cholesterol levels.

Control your weight with dried beans and peas. They're naturally low in fat and calories. A half cup has less than 1 gram of fat, and 100 to 120 calories. Their added fiber and protein at meals can help you feel fuller and more satisfied so you'll eat less.

Don't avoid these higher carbohydrate veggies if you have diabetes. Their fiber and complex carbohydrate cause a slower rise in blood sugar than some other starches. Carbohydrate varies among beans at 16 to 22 grams per half-cup.

Three Bean Salad is a delicious low-fat recipe with 15 grams carbohydrate, which counts as one serving of carbohydrate in a diabetes meal plan.

Part of the carbohydrate in beans is a complex sugar, which can't be broken down by the human digestive tract. It results in the gassy reputation of these beans; some are gassier than others.

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Practical Nutrition: Benefits of beans

Home Care Assistance Launches CenterSenior.com

Posted on February 29, 2012 by ev1

CenterSenior.com provides people eager to learn more about healthy longevity with scientifically based lifestyle tips that make a difference not only in how long we live but in how well we live.

Palo Alto, CA (PRWEB) February 28, 2012

CenterSenior.com is one among a large collection of educational initiatives Home Care Assistance is developing and promoting to provide education on topics that our clients and members of the community have expressed an interest in learning more about, said Kathryn Zakskorn, Public Relations and Marketing Manager of Home Care Assistance. We are excited to be in a position to distill this knowledge is an accessible and practical way that is beneficial to the community.

From health conscious young adults eager to add to their growing repertoire of health behaviors to seniors wanting to maintain or improve their current health status to caregivers hoping to find ways to promote healthy longevity for their loved ones, CenterSenior.com provides well-researched and practical advice for anyone wanting to learn more about aging well.

Its with a sense of both great pride and responsibility that we take up on the mantle for providing quality education around the topics of aging in place and healthy longevity, said Shadi Gholizadeh, Business Operations Manager of Home Care Assistance. Our mission at Home Care Assistance is to change the way the world ages; we want to empower aging adults to not only live longer but to live better longer.

For more information about Home Care Assistance please visit http://www.homecareassistance.com or call 1-866-454-8346.

ABOUT HOME CARE ASSISTANCE

Home Care Assistance is the leading provider of home care for seniors across the United States and Canada. Our mission is to change the way the world ages. We provide older adults with quality care that enables them to live happier, healthier lives at home. Our services are distinguished by the caliber of our caregivers, the responsiveness of our staff and our expertise in Live-In care. We embrace a positive, balanced approach to aging centered on the evolving needs of older adults. A 2012 Franchise500 Company, Home Care Assistance has received numerous industry awards including Entrepreneurs Fastest-Growing Franchises and Franchise Business Reviews Top 50. For more information about Home Care Assistance, our services and franchise opportunities, visit homecareassistance.com or franchise.homecareassistance.com.

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Kathryn Zakskorn Home Care Assistance 650-462-9501 Email Information

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Home Care Assistance Launches CenterSenior.com

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