The Anatomy of Media Bias: Trayvon Martin, Mike Daisey, and the Press

Julian Sanchez -- Research Fellow, Cato Institute

Like many folks who had seen and been moved by Mike Daisey's powerful monologue "The Agony and the Ecstasy of Steve Jobs," I was profoundly disappointed by the recent revelation that he had not only fabricated some of the work's key scenes, but lied to the journalists and fact checkers at This American Life to prevent them from discovering the deception. There's no point, at this stage, in adding another condemnation to the chorus, but I do want to highlight a pair of sharp pieces by Slate's Daniel Engberger and The Economist's Erica Grieder, responding to the common claim that Daisey's narrative was, as the saying goes, "fake but accurate."

While most commentary on the story has rightly rejected Daisey's invocation of "artistic license" to excuse the use of falsified anecdotes in a work of purported nonfiction, much of it includes the obligatory caveat that Daisey's larger point, the essential picture he paints of labor practices at Chinese suppliers like Foxconn, is true. So, for instance, in his performance, Daisey recounts how in a few hours of interviews outside just a couple of Foxconn plants, he encountered numerous underage workers--girls as young as 12 and 13 years old. Under pressure, he retreated to the claim that he'd spoken (in English) with one girl who identified herself as being 13, and seen several others who "looked young." The translator who accompanied Daisey on these interviews--the one he'd lied to prevent journalists from contacting--denies that there was even the one, and insists that she'd remember if there had been. Now, you don't get a gig as an English translator in China without staying on the good side of the Chinese government, so she might have her own incentive to downplay anything that reflects badly on the labor situation there--but all things considered, I'm inclined to agree with Ira Glass that her account comes across as much more credible than Daisey's.

Suppose we think Daisey probably did just make up this encounter. It's still undeniably the case that there have been underage workers employed by Apple suppliers: The company itself reports identifying 91 in an audit conducted in 2010, the year Daisey visited China. Thus, some argue, even if Daisey lied, the more important thing is that his dramatization reflected the underlying truth in an emotionally resonant way.

I agree with Engberger and Grieder that this line of argument is wrong, and that Daisey's pseudo-anecdote is substantively misleading when you consider what it's really meant to show. Nobody disputes that the number of underaged workers employed by Apple suppliers is greater than zero. But in the context of Foxconn's 300,000-strong workforce, in a country where (as the report suggests) parents are willing to procure fake IDs to help children obtain a coveted factory job, it's also probably not realistic to expect that this would never happen. The real question is whether Apple is making a good faith effort to enforce some screening procedures, identify and correct failures in the process when they occur, and so on.

Daisey's anecdote implicitly makes the far stronger claim that Apple is egregiously, culpably negligent here: Child labor is so prevalent that you scarcely need audits to find cases. Rather, a visitor standing at the gates of any randomly selected factory for a few hours will readily encounter numerous 12- and 13-year old kids who don't seem the least bit concerned about openly acknowledging their ages. Under those circumstances, as Daisey suggests, it would be hard to believe Apple wasn't well aware of, and deliberately winking at, a systemic indifference to the law.

If the point of the monologue were just to provoke an emotional reaction in the audience, as an artistic end in itself, maybe this wouldn't matter. But the monologue is explicitly and forcefully pitched as a call to both consumer activism and political action. In that context, it actually matters what the magnitude of this problem is, relative to others we might focus our time and energy on, and whether Apple is being especially irresponsible, relative to any number of other companies I might give my money to instead.

Those of you who recall the headline are probably wondering what this could possibly have to do with the tragic case of Trayvon Martin. I'll outsource the full rundown to Mother Jones, but the quick version is this:

In itself, that's a matter of news judgment that could probably be defended. But I want to suggest that the disparity here may have something to do with whether one thinks institutional racism remains a serious problem in the United States. Conservatives often seem to think it isn't, and that if anything, the real problem is how often spurious charges of white racism are deployed by their political opponents, while liberals more often tend toward the opposite view. Maybe both groups are drawing justified inferences from the data they're seeing.

Like child labor, institutionalized racism -- in the form of quiet bias as opposed to overt proclamations of white supremacy -- can be hard to detect and quantify rigorously. In both cases, the people closest to the problem have strong incentives to obscure and deny it. So people tend to fall back on what psychologists call the Availability Heuristic, a rule of thumb that says the frequency of an event should correspond to how quickly you can think of examples of it. We automatically pluralize anecdotes into data. Like much of our cognitive toolkit, it often misfires in the age of modern media--it's why people tend to be irrationally concerned with extremely rare threats, like child abduction by strangers, that draw disproportionate media attention.

Follow this link:
The Anatomy of Media Bias: Trayvon Martin, Mike Daisey, and the Press

Anatomy of a Media Bias: Trayvon Martin, Mike Daisey, and Us

Julian Sanchez -- Research Fellow, Cato Institute

Like many folks who had seen and been moved by Mike Daisey's powerful monologue "The Agony and the Ecstasy of Steve Jobs," I was profoundly disappointed by the recent revelation that he had not only fabricated some of the work's key scenes, but lied to the journalists and fact checkers at This American Life to prevent them from discovering the deception. There's no point, at this stage, in adding another condemnation to the chorus, but I do want to highlight a pair of sharp pieces by Slate's Daniel Engberger and The Economist's Erica Grieder, responding to the common claim that Daisey's narrative was, as the saying goes, "fake but accurate."

While most commentary on the story has rightly rejected Daisey's invocation of "artistic license" to excuse the use of falsified anecdotes in a work of purported nonfiction, much of it includes the obligatory caveat that Daisey's larger point, the essential picture he paints of labor practices at Chinese suppliers like Foxconn, is true. So, for instance, in his performance, Daisey recounts how in a few hours of interviews outside just a couple of Foxconn plants, he encountered numerous underage workers--girls as young as 12 and 13 years old. Under pressure, he retreated to the claim that he'd spoken (in English) with one girl who identified herself as being 13, and seen several others who "looked young." The translator who accompanied Daisey on these interviews--the one he'd lied to prevent journalists from contacting--denies that there was even the one, and insists that she'd remember if there had been. Now, you don't get a gig as an English translator in China without staying on the good side of the Chinese government, so she might have her own incentive to downplay anything that reflects badly on the labor situation there--but all things considered, I'm inclined to agree with Ira Glass that her account comes across as much more credible than Daisey's.

Suppose we think Daisey probably did just make up this encounter. It's still undeniably the case that there have been underage workers employed by Apple suppliers: The company itself reports identifying 91 in an audit conducted in 2010, the year Daisey visited China. Thus, some argue, even if Daisey lied, the more important thing is that his dramatization reflected the underlying truth in an emotionally resonant way.

I agree with Engberger and Grieder that this line of argument is wrong, and that Daisey's pseudo-anecdote is substantively misleading when you consider what it's really meant to show. Nobody disputes that the number of underaged workers employed by Apple suppliers is greater than zero. But in the context of Foxconn's 300,000-strong workforce, in a country where (as the report suggests) parents are willing to procure fake IDs to help children obtain a coveted factory job, it's also probably not realistic to expect that this would never happen. The real question is whether Apple is making a good faith effort to enforce some screening procedures, identify and correct failures in the process when they occur, and so on.

Daisey's anecdote implicitly makes the far stronger claim that Apple is egregiously, culpably negligent here: Child labor is so prevalent that you scarcely need audits to find cases. Rather, a visitor standing at the gates of any randomly selected factory for a few hours will readily encounter numerous 12- and 13-year old kids who don't seem the least bit concerned about openly acknowledging their ages. Under those circumstances, as Daisey suggests, it would be hard to believe Apple wasn't well aware of, and deliberately winking at, a systemic indifference to the law.

If the point of the monologue were just to provoke an emotional reaction in the audience, as an artistic end in itself, maybe this wouldn't matter. But the monologue is explicitly and forcefully pitched as a call to both consumer activism and political action. In that context, it actually matters what the magnitude of this problem is, relative to others we might focus our time and energy on, and whether Apple is being especially irresponsible, relative to any number of other companies I might give my money to instead.

Those of you who recall the headline are probably wondering what this could possibly have to do with the tragic case of Trayvon Martin. I'll outsource the full rundown to Mother Jones, but the quick version is this:

In itself, that's a matter of news judgment that could probably be defended. But I want to suggest that the disparity here may have something to do with whether one thinks institutional racism remains a serious problem in the United States. Conservatives often seem to think it isn't, and that if anything, the real problem is how often spurious charges of white racism are deployed by their political opponents, while liberals more often tend toward the opposite view. Maybe both groups are drawing justified inferences from the data they're seeing.

Like child labor, institutionalized racism -- in the form of quiet bias as opposed to overt proclamations of white supremacy -- can be hard to detect and quantify rigorously. In both cases, the people closest to the problem have strong incentives to obscure and deny it. So people tend to fall back on what psychologists call the Availability Heuristic, a rule of thumb that says the frequency of an event should correspond to how quickly you can think of examples of it. We automatically pluralize anecdotes into data. Like much of our cognitive toolkit, it often misfires in the age of modern media--it's why people tend to be irrationally concerned with extremely rare threats, like child abduction by strangers, that draw disproportionate media attention.

Read more:
Anatomy of a Media Bias: Trayvon Martin, Mike Daisey, and Us

2nd Lee Co. doctor’s license restricted in stem cell case

2nd Lee Co. doctor's license restricted in stem cell case

FORT MYERS, Fla.- Another Lee County doctor is caught in the center of a stem cell controversy. The State Department of Health has issued an emergency license restriction to Dr. Konstantine Yankopolus, a general practitioner.

Dr. Yankopolus is still allowed to practice general medicine and is treating patients. The license restriction mandates he can't do anything involving stem cell treatment.

It's business as usual at his office on Colonial Blvd.

The doctor is still treating patients, but an emergency order issued from the Florida Department of Health, Monday prevents him from doing anything with stem cells.

The order says Dr. Yankopolus' license "is hereby immediately restricted from providing, collaborating, facilitating, procuring, referring or advising on any stem cell treatment."

The action comes after the state suspended the license of his colleague, Dr. Zannos Grekos' earlier this month.

The emergency order says Dr. Yankopolus helped Dr. Grekos perform stem cell therapy on the late Richard Polling despite knowing the Bonita Springs cardiologist was not allowed to do such a procedure.

The state Surgeon General alleges, Dr. Yankopolus falsified Polling's records.

He writes, "Subsequent to the death of patient R.P., Dr. Yankopolus entered a false medical progress note in R.P.'s chart falsely indicating that no stem cell preparation was infused."

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2nd Lee Co. doctor's license restricted in stem cell case

Entest BioMedical Excited With Progress on 10 Dog Pilot Study of “Universal Donor” Stem Cell Treatment for Canine …

SAN DIEGO, CA--(Marketwire -03/21/12)- Entest BioMedical Inc. (OTCQB: ENTB.PK - News) (Pinksheets: ENTB.PK - News)

Entest BioMedical Inc. (OTCQB: ENTB.PK - News) (Pinksheets: ENTB.PK - News) and RenovoCyte LLC announced they have treated 8 canine patients of a 10 dog pilot study utilizing Canine Endometrial Regenerative Cells (CERC) licensed from Medistem Inc. (Pinksheets: MEDS.PK - News) in the treatment of canine osteoarthritis.

Previously, Entest announced the treatment of the first canine patient on November 18, 2011. Since that time Entest's McDonald Animal Hospital has treated 8 dogs in its 10 Dog Pilot Study with RenovoCyte. To date, all of the dogs participating in this study have shown dramatic improvement in their mobility and apparent reduction of pain.

Dr. Greg McDonald, Chief Veterinarian at McDonald Animal Hospital, said, "50 million CERC stem cells have been injected intravenously into eight dogs. Each dog selected for this study showed signs of arthritis. Follow-up blood tests, urinalysis and physical exams are now being scheduled for the patients that have already been treated. So far, all these canine patients have shown improvement."

Entest BioMedical Chairman David Koos stated, "Osteoarthritis is considered one of the most common causes of lameness in dogs, occurring in up to 30% of all dogs. It is caused by a deterioration of joint cartilage, followed by pain and loss of range of motion of the joint. We expect this treatment to relieve these animals from the pain associated with arthritis. This has extraordinary possibilities for dogs and may lead the way for human treatment of arthritic pain."

The CERC is a "universal donor" stem cell product that does not require matching with the recipient allowing for the generation of standardized products that can be delivered to the office of the veterinarian ready for injection. This is in stark contrast to current stem cell therapies utilized in veterinary applications which require the extraction, manipulation, and subsequent implantation of tissue from the animal being treated. CERC is the canine equivalent of Medistem's Endometrial Regenerative Cell (ERC). Medistem was recently granted approval from the FDA to initiate a clinical trial in human patients using its ERCs.

"We are extremely pleased with our research relationship with Entest BioMedical. This study of canine pets suffering from naturally occurring osteoarthritis is a better test model than laboratory induced disease because it will give us the opportunity for long term follow up of these patients. RenovoCyte sees this study as part of the supporting documentation that will be needed to obtain FDA approval for widespread usage of this therapy," said Shelly Zacharias, DVM, Director of Veterinary Operations, RenovoCyte, LLC.

A spokesperson for Entest noted the Company is also currently conducting a 10 dog safety study on its immune-therapeutic cancer vaccine for dogs, having treated 3 dogs so far.

About Entest BioMedical Inc.:Entest BioMedical Inc. (http://www.entestbio.com) is a veterinary biotechnology company focused on developing therapies that harness the animal's own reparative / immunological mechanisms. The Company's products include an immuno-therapeutic cancer vaccine for canines (ImenVax). ImenVax is less invasive and less traumatic in treating cancer. Additionally, the Company serves as the contract research organization conducting a pilot study on a stem cell based canine osteoarthritis treatment (developed by RenovoCyte LLC) utilizing a 'universal donor' stem cell. Entest is also building a network of veterinary hospitals (with its initial location in Santa Barbara, CA and anticipates acquiring other veterinary hospitals in California) -- which serve as distribution channels for its products.

DisclaimerThis news release may contain forward-looking statements. Forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted or quantified. Future events and actual results could differ materially from those set forth in, contemplated by, or underlying the forward-looking statements. The risks and uncertainties to which forward-looking statements are subject include, but are not limited to, the effect of government regulation, competition and other material risks.

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Entest BioMedical Excited With Progress on 10 Dog Pilot Study of "Universal Donor" Stem Cell Treatment for Canine ...

Stem Cell Therapy Could Boost Kidney Transplant Success: Study

TUESDAY, March 20 (HealthDay News) -- A novel technique that uses a kidney transplant recipient's own stem cells may someday replace or reduce the initial use of anti-rejection medications, new research suggests.

Six months after receiving a kidney transplant, only about 8 percent of people given their own mesenchymal stem cells experienced rejection compared with almost 22 percent of people on the standard anti-rejection drugs, according to the study.

"Mesenchymal stem cells are stem cells that can be differentiated into a variety of cells," explained Dr. Camillo Ricordi, study senior author and director of the Cell Transplant Center and Diabetes Research Institute at the University of Miami Miller School of Medicine.

"If you infuse mesenchymal stem cells at the time of the transplant, you could replace the use of powerful anti-rejection drugs, and maybe replace immunosuppressants altogether," he said. This technique could be used in the transplantation of islet cells (in the pancreas) for people with type 1 diabetes, and for other organ transplants, such as the liver, he added.

The people given their own stem cells also had improved kidney function earlier after transplant, Ricordi said.

Results of the study appear in the March 21 issue of the Journal of the American Medical Association.

One of the biggest remaining hurdles in organ transplantation remains the need for powerful anti-rejection and immune-suppressing medications after the transplant.

"Basically, the way we prevent kidney rejections is by putting you on very powerful anti-rejection drugs and immunosuppressive agents to prevent your cells from attacking the foreign organ," said Dr. Robert Provenzano, chair of the department of nephrology, hypertension and transplantation at St. John Providence Health System in Detroit. "But, the current standard has some problems, like an increased risk of infections and the possibility of creating a cancer."

The body's immune system sends out surveillance cells to protect the body against foreign invaders, such as a bacteria, virus or, in this case, a new organ, Provenzano said. The current method of preventing these cells from attacking the new organ is essentially to destroy the surveillance cells. But mesenchymal cells can naturally suppress those surveillance cells so they don't attack, he said.

To see if this suppression would be enough to prevent rejection, Ricordi and his colleagues, including researchers from Xiamen University in China, recruited 159 people with serious kidney disease who were on dialysis. They ranged in age from 18 to 61.

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Stem Cell Therapy Could Boost Kidney Transplant Success: Study

Evaluating Sex Differences in Medical Device Clinical Trials: Time for Action [Viewpoint]

Sanket S. Dhruva, MD; Rita F. Redberg, MD, MSc Author Affiliations: Department of Medicine (Dr Dhruva), and Women's Cardiovascular Services, School of Medicine, Division of Cardiology (Dr Redberg), University of California, San Francisco. Dr Redberg is also Editor, Archives of Internal Medicine.

The safety and effectiveness of medical treatments can differ in men and women for many reasons related to different epidemiologic characteristics, physiology, and body size. In general, women have higher bleeding rates and procedural morbidity and mortality than men, which means that their risk/benefit ratios for many implanted medical devices can differ from men. Therefore, sex-specific safety and effectiveness data are necessary for informed patient decision making. In 2008, the US Food and Drug Administration (FDA) convened 2 workshops on this topic that included multiple stakeholderspatient groups, medical device industry representatives, academia, and government officials. In December 2011, the FDA released a draft guidance informed by these workshops, entitled Evaluation of Sex Differences in Medical Device Clinical Studies.1 This document discusses the underrepresentation of women in medical device clinical trials and provides recommendations for increasing enrollment of women and performing sex-specific analyses. A 90-day public comment period began on

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Evaluating Sex Differences in Medical Device Clinical Trials: Time for Action [Viewpoint]

Aurora Joins Hitachi Data Systems Technology Alliance Program to Offer Best- In-Breed Data Management and Digital …

MONTREAL, QUEBEC--(Marketwire -03/20/12)- Aurora Interactive announced today that it has joined the Hitachi Data Systems Technology Alliance Program. This will allow Aurora to deliver data management and digital pathology solutions to their clients, giving clients timely control of their data and medical choices.

"Aurora is proud to join the Hitachi Data Systems Technology Alliance Program. Hitachi Data Systems is a globally respected leader in the IT industry, and one of the premier technology and services providers to the medical field. Joining this program will allow us to seamlessly fulfill the needs of our clients who have taken the next step in digital pathology adoption and require universal and vendor neutral mass data management solutions. Our participation in the Hitachi Data Systems Technology Alliance Program is fully aligned with our strategy of universality and interoperability and our commitment to giving our clients control over their data and medical choices. As HDS believes that data drives our world and information is the new currency, Aurora believes that timely and efficient data and information access is the key to better patient care and outcomes," stated Pierre Le Fevre, President and Chief Executive Officer, Aurora Interactive.

"Hitachi Data Systems would like to welcome Aurora Interactive to our Technology Alliance Program. We strongly believe in partnering with best-in-breed providers to bring our clients leading technologies to pair with our data management systems. Aurora Interactive is an ideal digital pathology partner for us," said Dave Wilson, senior director, Global Health Solutions,, Hitachi Data Systems.

About Aurora Interactive Ltd.

Aurora Interactive has developed the leading web based software platform (mScope) for simplification, productivity and ease of communications. mScope's Universal Web Viewer has collaborative tools to view medical slides and images anytime, anywhere, regardless of file format. The software has four applications to aid digital pathology web based communications needs: mScope Education, mScope Clinical, mScope Research and mScope Universal Viewer.

Aurora's mission is to improve patient outcomes and help members of the medical community achieve their full potential by eliminating the learning, diagnostic and collaborative restrictions imposed by time and space.

http://www.aurorainteractive.com

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Aurora Joins Hitachi Data Systems Technology Alliance Program to Offer Best- In-Breed Data Management and Digital ...

Good nutrition essential to protect health of elderly people

WATERLOO Malnutrition is a big problem among older adults that can lead to serious health problems and steady decline in ability if they dont adopt a healthier diet, a University of Waterloo researcher says.

Older adults need more nutrients than we think and catching it early is key, said Heather Keller, a registered dietitian and Schlegel research chair in nutrition and aging at the Schlegel-UW Research Institute for Aging.

Keller will share her expertise in senior nutrition at a free public lecture on Wednesday at the Kitchener Market from 4 to 5:30 p.m. She will provide information on nutrient needs and useful strategies and resources.

Keller works with older adults in the community as well as families and practitioners to share her knowledge on the importance of a healthy diet and how to ensure elderly people are getting enough essential nutrients. She developed a simple questionnaire to identify where older adults are doing well and where improvement is needed ( http://www.eatrightontario.ca/escreen).

Older adults think theyre doing fine, Keller said.

Yet often theyve slipped into bad habits, such as skipping meals. Snacking, and weight loss can follow. Thats a problem because older adults primarily lose muscle and not fat, increasing the risk of balance problems and falls.

Nutrition needs change as a person ages because their body doesnt process nutrients in the same way, making healthy eating essential to prevent and manage health conditions but also more complicated.

Older adults dont realize they need more nutrition in less calories, said Keller, who is now studying how to improve nutrition in long-term care homes.

Although its commonly known elderly people need more calcium, other nutrients need to be boosted to protect health. Vitamin D, for instance, is often lacking in older adults because skin changes affect the ability to make the vitamin through sun exposure. Substantially more protein is needed to maintain muscle mass.

Older adults soon show the effects of poor nutrition because they dont have the same reserves as young adults, who can quickly recover from a bout of bad eating. Possible health effects include osteoporosis, loss of function, cognition issues, including early onset dementia, delirium and balance problems.

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Good nutrition essential to protect health of elderly people

Shadow Beverages Selects Closure Systems International Closures for New GNC Advanced Nutrition Drinks

INDIANAPOLIS--(BUSINESS WIRE)--

Closure Systems International is pleased to announce that its Extra-Lok V 38mm OD cap has been selected for use on a new line of GNC Advanced Nutrition Beverages. GNC, one of the world's largest specialty retailers of nutritional products, has been helping people Live Well for more than 75 years by offering a variety of health and wellness supplements, ranging from vitamins to diet and sports nutrition products. With its licensee partner, Shadow Beverages LLC, GNC has now entered the ready-to-drink beverage category in new markets with an extensive range of Nutritional Waters, Sport Nutrition, and Protein Nutrition Beverages. The range meets the targeted needs of all levels of active consumers.

The GNC beverage line includes XP / Extreme Performance drinks, targeted towards intense performance athletes that push themselves above and beyond, and Active drinks, formulated to meet the hydration and metabolic needs of more mainstream active consumers. The GNC Nutritional Waters, Sport Nutrition, and Protein Nutrition Beverages are packaged in 20 oz. and 14oz PET bottles by Graham Packaging. The XP beverage lines have black labels and black closures, while the Active bottles have white labels and clear closures.

CSIs versatile, light-weight Extra-Lok V 38mm OD cap was chosen over alternative closure options due to its premium look, consumer safety features, and optimal sealing and application performance. Equally important were the technical expertise and customer services CSI provided, according to Allen Warner, Director of Supply Chain for Shadow Beverages. "At each step, CSI provided unmatched technical service and on-time delivery. For us, the decision was easy, said Warner. CSI is the worldwide leader in beverage closures and exceeded our expectations by meeting extremely tight project timelines, he added. With CSIs expert guidance, we enjoyed a smooth, trouble free bottling start-up.

The new line of GNC beverages delivers everything active consumers have come to expect from the leader in healthy innovation significantly superior nutrition. Extending the GNC brand portfolio to include nutritionally enhanced ready-to-drink beverages makes perfect sense, and Shadow Beverages has done an excellent job developing just the right product and packaging, said CSI Sales Manager, Sussy Goff. CSI is thrilled to be a part of such an exciting launch.

Distribution of the new line of GNC beverages, currently consisting of 14 SKUs, has begun through various channels in the United States. To learn more go to http://www.drinkGNC.com.

For further closure information, please contact:

Rodolfo Haenni, Global Marketing Manager Closure Systems International 7702 Woodland Dr, Suite 200 Indianapolis, Indiana 46278 USA Rodolfo.Haenni@csiclosures.com 317-390-5073

For further product information, please contact:

Eric Fling, VP of Field Marketing Shadow Beverages & Snacks LLC 4650 E. Cotton Center Blvd, Suite 240 Phoenix, AZ 85040 ericf@shadowbev.com 480-371-1100

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Shadow Beverages Selects Closure Systems International Closures for New GNC Advanced Nutrition Drinks

Reality check on ‘Hunger Games’ tech

Murray Close / Lionsgate / Everett Collection

Peacekeepers escort Katniss Everdeen (Jennifer Lawrence) in a scene from "The Hunger Games."

By Alan Boyle

The technological divide between the rulers and the ruled is at the heart of "The Hunger Games": While the good guys struggle to survive, the bad guys employ fictional gee-whiz technologies inspired by real-life frontiers. And just as in real life, technology gets tripped up by unintended consequences.

That's not to say the post-apocalyptic North America of the book series and the much-anticipated movie, opening Friday, is anything close to real life. On one level, the technologies used by the villainous government of the nation known as Panem, ranging from force fields to extreme genetic engineering, serve as science-fiction plot devices and special effects. But on another level, the contrast between bows and arrows on one side, and death-dealing hovercraft on the other, accentuates the saga's David vs. Goliath angle or, in this case, Katniss vs. the Capitol.

Here are a few of the technological trends that provide the twists in "The Hunger Games," along with real-world analogs:

What? No cellphones? Much has been made of the fact that the starving, downtrodden residents of Panem's districts don't seem to have access to cellphones or the Internet. Instead, they have to huddle around giant television sets to find out what their overlords in the Capitol want them to see. But if you think of Panem as a fictional tweak of modern-day North Korea, "The Hunger Games" might not be that far off the mark: You've got a leadership capable of long-range missile launches, exercising virtually total control over what its impoverished populace sees and hears. Cellphones were outlawed until 2008, and even today they're confiscated from international visitors upon arrival. Internet access and international calling are limited to the elite.

The outlook for change is mixed: Today, a million North Koreans are said to be using mobile phones, but the State Department's Alec Ross told the Korea Times during a recent visit to Seoul that "it will be very difficult for technology to drive change in North Korea, given the extreme measures that North Korea has taken to create a media blackout." That's life in Panem ... er, Pyongyang.

Genetic engineering The most vivid special effects are connected to genetic engineering of various organisms, including humanized animals. To minimize the plot-spoiler effect, the only "muttation" I'll mention in detail is the mockingjay, which figures so prominently in the advance publicity and provides the title for the third book in Suzanne Collins' "Hunger Games" trilogy. The geniuses at the Panem high command created genetically modified birds known as jabberjays that were able to listen in on rebel conversations and report them back to the authorities. When the rebels caught onto this, they started feeding the jays false information. And when the Capitol figured this out, they left the jabberjays to fend for themselves. Male jabberjays mated with female mockingbirds, resulting in birds that could learn and repeat musical notes but not human speech.

The twist illustrates a time-honored movie maxim about genetic engineering, enunciated in the first "Jurassic Park" film: "Life will not be contained." That may be putting it too simply, but the field has certainly raised a lot of questions about how to keep genetic genies in the bottle. This month, more than 100 groups issued a call to hold back on synthetic biology until new guidelines are drawn up.

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Reality check on 'Hunger Games' tech

'Nanoslinky': A novel nanofluidic technology for DNA manipulation and measurement

In the first of two recent papers*, Samuel Stavis, Elizabeth Strychalski and colleagues demonstrated that a nanoscale fluidic channel shaped like a staircase with many steps (developed previously at NIST and Cornell University) can be used to control the otherwise random drift of a DNA molecule through a fluid. Squeezed into the shallowest step at the top of the staircase, a strand of DNA diffuses randomly across that step. The DNA molecule seeks to increase its entropythe universal tendency towards disorder in a systemby relieving its confinement, and therefore, walks down onto the next deeper step when it reaches the edge. The motion of the molecule down the staircase, which the researchers termed entropophoresis (entropy-driven transport), ends when it becomes trapped on the deepest step at the bottom. Because this motion resembles that of a Slinky, the researchers nicknamed their system the nanoslinky. The researchers found that DNA molecules of different sizes and shapes descended the staircase at different rateswhich suggests the structure could be used to separate, concentrate and organize mixtures of nanoscale objects.

Stavis says that this novel technology provides advantages over traditional nanofluidic methods for manipulating and measuring DNA. Control over the behavior of a DNA molecule is built into the staircase structure. After placing the molecule on the top step [by driving the DNA strand up the staircase with an electric field], no external forces are needed to make it move, Stavis says. The staircase is a passive nanofluidic technology that automates complex manipulations and measurements of DNA.

This NIST advance in nanofluidic technology dovetails nicely with a NIST innovation in measurement sciencespecifically, determining the size of a DNA molecule in nanofluidic slitlike confinement imposed by the narrow gap between the floor of each step and the ceiling of the channel. In the nanoslinky system, Strychalski explains, the coiled and foldedDNAstrandcontracts progressively as it moves down the steps. Because there are many steps, we can make more detailed measurements than previous studies, she says.

Getting the most from those measurements was the goal of the research reported in the NIST teams second paper.** The challenge was to make our measurements of DNA size more quantitative, Strychalski says.

Previous measurements of DNA dimensions in nanofluidic systems, Strychalski says, have been limited by imaging errorsfrom the optical microscopes used to measure the dimensions of DNA molecules labeled with a fluorescent dye. The first problem is the diffraction limit, or the optical resolution, of the fluorescence microscope, she says. The second problem is the pixel resolution of the camera. Because a DNA molecule is not much larger than the wavelength of light and the effective pixel size, images of fluorescent DNA molecules are blurred and pixilated, and this increases the apparent size of the molecule.

To improve their measurements of DNA molecules during their descent, the NIST researchers used models to approximate the effects of diffraction and pixilation. Applying these numerical simulations to the images of DNA molecules confined by the staircase made the final measurements of DNA size the most quantitative to date. These measurements also showed that more work is needed to fully understand this complicated system.

According to Stavis and Strychalski, the staircase is a simple prototype of a new class of engineered nanofluidic structures with complex three-dimensional surfaces. With further refinements, the technology may someday be mass produced for measuring and manipulating not just DNA molecules, but other types of biopolymers and nanoscale materials for health care and nanomanufacturing.

More information: *S.M. Stavis, et al. DNA molecules descending a nanofluidic staircase by entropophoresis. Lab on a Chip (2012). DOI: 10.1039/c21c21152a

**E.A. Strychalski, et al. Quantitative measurements of the size scaling of linear and circular DNA in nanofluidic slitlike confinement. Macromolecules (2012). DOI: 10.1021/ma202559k

Provided by National Institute of Standards and Technology (news : web)

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'Nanoslinky': A novel nanofluidic technology for DNA manipulation and measurement

Posted in DNA

DNA test casts doubt on 1983 Miramar rape and murder case

Laboratory testing has shown that a Broward man locked up since he was 15 for the rape and murder of a Miramar woman in 1983 is not the source of the DNA found on the victim's body.

Anthony Caravella, now 41, has spent 25 years, or more than half his life, in prison.

"This means Anthony is innocent, it exonerates him," said Diane Cuddihy, the Broward chief assistant public defender who reopened Caravella's case and has been working on it since 2001.

McCann said she needs to know more about how the private forensic lab that did the testing came up with results so at odds with findings from the Broward Sheriff's Office crime lab eight years ago.

"This is a scientific inquiry at this point," the prosecutor said.

The test, performed by a private lab in Richmond, Calif., eliminated Caravella as a potential source for the sperm found inside the Miramar victim's body 26 years ago.

The test yielded the DNA profile of an unidentified male that could be checked against genetic databases to see if there's a match with anyone on file.

In 2001, the sheriff's crime lab reported that testing of the evidence produced nothing that would either implicate or exonerate Caravella. Further, the technicians said, there was no semen found.

Broward Sheriff's Office spokesman Jim Leljedal said Wednesday that the agency's crime technicians will ask Forensic Science Associates, the California lab, to share their methods and results "so we can take another look at this."

Miramar police, who investigated the 1983 murder with help from the Sheriff's Office, also will review the case in light of the new information, spokeswoman Tania Rues said.

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DNA test casts doubt on 1983 Miramar rape and murder case

Posted in DNA

DNA targets stomach worm

DNA technologies are being aimed at the lowly stomach worm, the bane of sheep producers in high rainfall areas.

By the end of the year, a CSIRO teams aims to have a DNA-based test that will tell sheep producers the worm species they are dealing with, and the level of infestation, at 10 times the accuracy of current tests, with results delivered in a fraction of the time.

In time, CSIRO scientist Peter Hunt said, the test may be used for multiple functions - assessing liver fluke infestation, assessing drug resistance, assigning breeding values for worm resistance, and even for determining parentage and other breeding values that might otherwise be done in a separate test.

The pilot test to be made available at the end of 2012, through NSW Department of Primary Industry's Camden laboratories, is the culimination of about a decade's work by CSIRO and collaborating scientists.

Worm tests are conducted on faeces, a complex substance that is chock-full of DNA, including that of the animal that produced it.

Dr Hunt, who led the research, said considerable effort went into identifying sequences of DNA that provide a unique signature for each of the three species of interest - the black scour, barbers pole and small brown stomach worms.

An additional breakthrough arrived with the recent surge in molecular DNA technologies, which has allowed researchers to extract DNA from the faecal murk so that it can be assessed for the characteristic signature sequences of the parasites.

The technology will, at least initially, deliver much the same results as current worm egg count tests do, but with much greater accuracy, and a 48-hour turnaround time compared to the week currently needed.

But Dr Hunt said it is the additional possibilities that will make the technology revolutionary.

CSIRO scientist Jody McNally has been awarded a NSW DPI Young Scientists Science and Innovation award that will allow her to work on adding liver fluke to the DNA testing procedure.

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DNA targets stomach worm

Posted in DNA

DNA murder scene match, jury told

20 March 2012 Last updated at 17:59 ET

Blood found at a Pembrokeshire woman's home partially matched the DNA profile of the man accused of her murder, Swansea Crown Court has heard.

John William Mason, 55, is accused of beating to death Angelika Dries-Jenkins, 66, at Narberth last year.

The prosecution claims the possibility of partial DNA matches from blood and fibres found by the inquiry coming from other people were one in a billion.

Mr Mason denies murder and the case continues.

The court has previously been told that Ms Dries-Jenkins was savagely beaten to death with a blunt instrument by Mr Mason because he needed the money to pay for his wedding.

He is said to have withdrawn 1,000 from her bank accounts, having stolen her handbag and her Skoda Fabia car, leaving her dead or dying.

On Tuesday, forensic scientist Martin Whittaker gave in detail the results of DNA testing at Ms Dries-Jenkins' house, her car and on a jumper which the prosecution says Mr Mason discarded in a bin in Haverfordwest.

Mr Whittaker said he found limited DNA profiles on a number of objects in the house but in Ms Dries-Jenkins' car he found a full profile which matched the defendant on the car keys.

He said he also found a DNA profile of Mr Mason on the neck of the jumper found in a bin, along with blood from Ms Dries-Jenkins.

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DNA murder scene match, jury told

Posted in DNA

OEB Students Take Sponsored Spring Break Trips

Leatherback turtles slowly crawled along the Costa Rican shores to lay their eggs as Harvard students watched carefully nearby in the nighttime.

This year, three classes from the Organismic and Evolutionary Biology Department offered all-expenses-paid spring break trips for its students.

Twenty-seven students traveled to Panama for trips offered by OEB 51: Biology and Evolution of Invertebrate Animals and OEB 190: Biology and Diversity of Birds, while 21 students in OEB 167: Herpetology studied amphibians and reptiles in Costa Rica.

This year marked OEB 51s seventh trip to Panamas tropical coasts. Students spent each day diving into the water to collect and photograph specimens before bringing them to the lab for further investigation.

OEB Associate Professor Cassandra Extavour, who led the trip with OEB Professor Gonzalo Giribet, said that she hopes the trip helped students understand invertebrates and the importance of anatomical study.

Theres no better way to understand biology than to get inside itwhether its seeing organisms in the wild or seeing the inside of a cell through high resolution microscopy, said Extavour. That visual and tactile element is very important in cementing the students learning.

Diversity that had been enumerated in course lectures came to life for OEB 51 students once they strapped on their snorkels.

The underwater topography was steep, and it was amazing to see the distribution and sheer diversity of the corals, sponges, starfish, sea urchins, squid, snails, jellyfish, [and] shrimp..., wrote Emily A. Burke 14 in an emailed statement. The list goes on, and...its hard to just pick out a few favorite [organisms] or isolate them from each other because everything is so intricately connected.

In Costa Rica, OEB Professors Jonathan B. Losos 84 and James Hanken assigned their OEB 167 students the task of becoming resident experts in specific reptile and amphibian species before the trip. Throughout the week, the students shared information about their organisms as they encountered them in the wild.

We get to see the habitats and microhabitats that [these organisms] are found in, hear them calling, [and] see them eating, said Hanken.

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OEB Students Take Sponsored Spring Break Trips

Shell donates $50,000 to Nicholls

Published: Tuesday, March 20, 2012 at 10:16 p.m. Last Modified: Tuesday, March 20, 2012 at 10:16 p.m.

Oil industry giant Shell has donated $50,000 to Nicholls State Universitys biology department to strengthen a native-plants program.

The money will support the Louisiana Plant Initiative, which is spearheaded by the schools biology program and involves several universities throughout the state.

The initiative uses students, instructors and community volunteers to distribute native plants used to help bolster coastal Louisiana.

Allyse Ferrara, a biology professor who leads the project, said the Shell donation will allow flexibility. Grants typically come with strict spending guidelines.

If something breaks that we cant pay for with a grant, this will let us fix it, she said. It allows us to have the freedom to go do additional things that arent funded by our other grants.

Ferrara and her team grow plants that are native to coastal Louisiana and help keep the ecosystem balanced. Grasses, weeds and other plants not native to the area often have different growth cycles that dont support local animal life nearly as well as native species.

So far, the project has planted thousands of native grasses and mangrove trees in places like Grand Isle, Elmers Island, Leeville and the Fourchon area. Ferrara said the native plants will help spur growth of plants and animals, resist invasive species and anchor the soil against erosion.

The project also keeps a stock of plants inland in case floods, hurricanes or other events destroy swaths of plant life.

Lets say theres some sort of catastrophe, Ferrara said. This will let us move in quickly and replace the lost ground to prevent that damage from becoming permanent.

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Shell donates $50,000 to Nicholls

SPVM holds scientific seminar in Dipolog

by Franklin P. Gomapon

DIPOLOG CITY The Andres Bonifacio College hosted the scientific seminar in Physics, Chemistry, Mathematics and Biology held recently at the Arts, Graduate and Professional Schools (AGPS) building of the said school.

The said seminar was spearheaded by the Samahang Pisika ng Visayas at Mindanao (SPVM) and the College Extension Committee (CEC) of the College of Sciences and Mathematics (CSM), Mindanao State University-Iligan Institute of Technology (MSU-IIT), Iligan City.

Lectures in the field of Physics, Chemistry, Mathematics and Biology were delivered by well-known researchers and professors from MSU-IIT.

For Physics, Dr. Reynaldo M. Vequizo, SPVM President and chairman of the Physics department, talked about Identifying Key Properties of Materials using Radiation: The Case of XRD and with Electron Beam while Dr. Arnold C. Alguno talked on the topic, Emerging Materials Science Trends: The MSU-IIT Experience.

Prof. Rosario L. Reserva also gave a lecture-demonstration on some physics apparatuses fabricated by the institutes physics department which are being used in mechanics experiments.

Dr. Ruth P. Serquia of the department of Mathematics, on the other hand, gave a lecture on computer simulation in Mathematics while Prof. Catherine R. Cano discussed sequential analysis and its applications.

Biologists Dr. Mark Anthony Torres and Dr. Cesar Demayo, chairman of the biological sciences department of MSU-IIT, talked on the trends in life science research and biology graduate programs, respectively.

The scientific seminar, participated by teachers from the elementary, secondary and tertiary levels, was organized to enhance the science and mathematics teaching capabilities of teachers and to facilitate deeper learning among students through research.

With the different graduate programs offered by MSU-IIT, particularly by the College of Sciences and Mathematics, the speakers invited the participants to apply and take up graduate studies at the said university as slots are still available under the scholarship program of the Commission on Higher Education (CHED) and the Department of Science and Technology (DOST).

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SPVM holds scientific seminar in Dipolog

Why getting healthy can seem worse than getting sick

Public release date: 20-Mar-2012 [ | E-mail | Share ]

Contact: Kevin Stacey kstacey@press.uchicago.edu 401-284-3878 University of Chicago Press Journals

A new article in The Quarterly Review of Biology helps explain why the immune system often makes us worse while trying to make us well.

The research offers a new perspective on a component of the immune system known as the acute-phase response, a series of systemic changes in blood protein levels, metabolic function, and physiology that sometimes occurs when bacteria, viruses, or other pathogens invade the body. This response puts healthy cells and tissue under serious stress, and is actually the cause of many of the symptoms we associate with being sick.

"The question is why would these harmful components evolve," asks Edmund LeGrand (University of Tennessee, Knoxville), who wrote the paper titled with Joe Alcock (University of New Mexico). The researchers contend that answer becomes clear when we view the acute-phase response in terms of what they call "immune brinksmanship."

The immune brinksmanship model "is the gamble that systemic stressors will harm the pathogens relatively more than the host," LeGrand said. The concept, he explains, is akin to what happens in international trade disputes. When one country places trade sanctions on another, both countries' economies take a hit, but the sanctioning country is betting that its opponent will be hurt more.

"One of our contributions here is to pull together the reasons why pathogens suffer more from systemic stress," LeGrand said.

The acute-phase response creates stress in several ways. It raises body temperature and causes loss of appetite and mild anemia. At the same time, certain vital nutrients like iron, zinc, and manganese are partially sequestered away from the bloodstream.

Some of these components are quite puzzling. Why reduce food intake just when one would expect more energy would be needed to mount a strong immune response? Zinc is essential for healthy immune function. Why pull it out of the bloodstream when the immune system is active? The benefits of a stressor like fever are fairly well known; heat has been shown to inhibit bacterial growth and cause infected cells to self-destruct. But what hasn't been clear is why pathogens should be more susceptible to this stress than the host.

LeGrand and Alcock offer some answers. For an infection to spread, pathogens need to multiply, whereas host cells can defer replication. Replication makes DNA and newly forming proteins much more susceptible to damage. It also requires energy and nutrientswhich helps explain the benefits of restricting food and sequestering nutrients.

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Why getting healthy can seem worse than getting sick

What was B.F. Skinner really like? A new study parses his traits

Public release date: 20-Mar-2012 [ | E-mail | Share ]

Contact: Lucy Hyde lhyde@psychologicalscience.org 202-293-9300 Association for Psychological Science

March 20th marks the birthday of famed behavioral psychologist B.F. Skinner, who would have turned 108 today. Besides Sigmund Freud, B.F. Skinner was the most famous and perhaps the most influential psychologist of the 20th century. But his own "radical behaviorism"the idea that behavior is caused solely by environmental factors, never by thoughts or feelingsmade him a magnet of controversy, which grew even more intense with the publication of his best-known book, Beyond Freedom & Dignity.

"He was looked at as beyond the pale by a lot of other psychologists, including me," says Dean Keith Simonton, a psychologist at the University of California Davis, who was a graduate student at Harvard when Skinner taught there. Some even called Skinner a fascist for his radical views of human malleability. But, says Simonton, "people who knew him would also say, 'You really should talk to Skinner, because he's a much broader, more open person than you think.'"

Who was B.F. Skinner? University of Oslo psychologists Geir Overskeid and Cato Grnnerd, along with Simonton, used a variety of source material plus an instrument that scores people on five major personality factors, to describe him and compare him with other eminent scientists. The study, which appears in Perspectives in Psychological Science, a journal published by the Association for Psychological Science, reveals a complex manbut nothing like the monster his detractors called him.

To draw an objective picture of Skinner, the psychologists first combed through published sources both biographical and autobiographical, archival material, and sketches written by people who knew him. From these they culled 118 descriptive words and phrases, from "fanatic" to "afraid of the police." Five raters blind to the subject's identity categorized each descriptor under the Big Five traits that psychologists use to describe personalityOpenness, Conscientiousness, Agreeableness, Extroversion, and Neuroticismand assigned to the descriptor a degree from -2 to +2. The authors chose the 81 descriptors on which four of the five raters agreed; there was almost complete agreement as to degree.

The results: Skinner was highly conscientiousscoring 1.8working tirelessly and meticulously toward ambitious goals. Indeed, he wrote that he aimed to remake the "entire field of psychology" and viewed relaxation as dangerous. And those Harvard students were right about Skinner's openness to experience. Besides being a psychologist, he painted, wrote a novel, played saxophone and piano, and enjoyed all kinds of music. He was also somewhat neurotic and extroverted: known as charming, funnyand a womanizer.

In many respects, Skinner's is the profile of an eminent scientistfor his drive and discipline, creative versatility, and also for his neuroticism, a trait shared by as many as 45% of leading scientists, according to one analysis. What the profile does not represent: an evil authoritarian. "This article makes Skinner more human," says Simontonnot just a "consolidation" of traits but also an array of nuanced detail. Though objective, it's not "a polarizing treatment. You don't have to love or hate him."

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To learn more about B.F. Skinner, you can also read this profile and interview recently featured in the APS Observer.

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What was B.F. Skinner really like? A new study parses his traits

Third Aesthetic Plastic Surgery / Anti Aging Medicine: The Next Generation Symposium Brings Industry Leading Courses …

New York, March 21, 2012 /PRNewswire/ --The third Aesthetic Plastic Surgery / Anti Aging Medicine: The Next Generation Symposium will be held on July 20-22, 2012 at the Conrad New York, a new luxury complex overlooking the Hudson River in lower Manhattan. This interactive, multidisciplinary conference brings together world-class faculty from around the globe who will share ground-breaking research and practical advancements in aesthetic surgery, cosmetic medicine and anti-aging therapy.

The Next Generation Symposium combines the best of continuing medical education, state-of-the-art information that is presented in a manner that encourages forward thinking among the core specialties of Plastic Surgery, Facial Plastic Surgery, Dermatology and Oculoplastic Surgery. Now in its third year, The Next Generation Symposium is distinguished for providing attendees a multitude of practical hands-on instruction, expert insights and pearls from world renowned experts in the field.

As Course Chairman Z. Paul Lorenc, M.D., F.A.C.S states, "We are focused on what is happening now, what is coming next and what the future will bring."

NEW for 2012:

The meeting encourages excellent interaction and discussion among the international core specialty faculty, fostering an atmosphere of different points of view, which creates a positive learning experience. "The Next Generation Symposium will continue to deliver both in the quality of the presentations and the scope of the program," states Executive Co-Chairman,Brian M. Kinney, M.D., F.A.C.S.

About Aesthetic Plastic Surgery & Anti-Aging Medicine: The Next Generation An interdisciplinary approach to disseminating, teaching and promoting the most advanced information and developments in the fields of aesthetic plastic surgery and anti-aging medicine. In view of the rapid pace in development of new technology and techniques employed in these fields, collectively we feel that it is critical that new information is shared in an efficient, unbiased, forward looking manner with the focus of enhancing patient's safety and level of care.

For information about sponsorship opportunities and early bird registration, visit http://www.nextgenmtg.org

Like us on http://www.facebook.com/apssny and follow us on http://www.twitter.com/nextgenmtg for daily updates and additional workshops

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Third Aesthetic Plastic Surgery / Anti Aging Medicine: The Next Generation Symposium Brings Industry Leading Courses ...