The biological defects that come with age and how to prevent them – Ladders

I mightve died fearing the ageing process about as much as everyone else. Unfortunately, about two drags into my fourth cigarette a friend of mine relayed an anecdote about his dying grandfatherunprompted.

So its his ninety-eighth birthday and were watching him try to blow out candles on a cake he probably cant eat anywayfor like an hour.Eventually, I get bored and blow it out for him before asking what he wished for. To which he says: I accidentally peeped the expiration date on the carton of milk in the fridge and it dawned on me that I didnt know which one of us had more time left.

In an instant, I quit smoking and took up gerascophobia. In defense of the soon-to-be-dead-party-pooper, the older we get the louder minute hands become. We try to dull the racket by route of cosmetics, pop culture, copulation and fairy-tales; all to distract ourselves from the inevitable frog march into nothingness. If were honest, every year after 50 extends a catalog of things we cant do anymore. The list begins innocuously enough with things like fit into my favorite pair of whatevers or comprehend the cultural significance of this or that, but then the whole thing ends tragically nuanced.

Were all familiar with the odd way time seems to speed up every year after 21? It makes sense that time adopts the illusion of expedience as we run out of milestones but the reasoning behind this phenomenon is actually even less abstract than that. According to a new paper published in the scientific journalEuropean Review, as wrinkles begin to appear, and our postures sag, our neurons grow larger, increasing the amount of time it takes us to process an image.

People are often amazed at how much they remember from days that seemed to last forever in their youth, explained the new studys author Adrian Bejan, the J.A. Jones Professor of Mechanical Engineering at Duke University in a pressrelease.Its not that their experiences were much deeper or more meaningful, its just that they were being processed in rapid-fire.

Interestingly enough, almost all of the psychological conditions that narrate our morph into maggot food are effected by well-documented physiological precursors.

Little mutations join forces to pen an aggressive eviction notice apostrophized by medical abnormalities that condemn life on planet earth to be less and less pleasant.This is especially relevant right now because Americas global age is increasing at an exponential rate.

When a society attains economic and agricultural excellence the death rate decreases alongside birthrate, which leads to a larger and older population.James Fries, professor of medicine at Stanford University, indexed the sociological fine-print that punctures this developmental achievement back in 1998. What Fries calls the compression of morbidity dictates that denizens of a thriving nation enjoy healthy lives for most of it until a series of health setbacks plague them all at once toward the final stretch. This is often in the form of chronic illness that appears in tandem with natural biological regressions. As far as the perversion of our mind clocks are concerned, organic changes in saccades frequency, body size, and pathway degradation have been studied to be the primary culprits. This is what physics more discreetly refers to asthe constructional law of low architecture. Elderly people simply receive fewer images in the same amount of time as younger people, drastically decelerating their integration of information. The mechanisms that animate this process are fairly identical to a cameras shutter speed.

The human mind senses time changing when the perceived images change, Bejan adds. The present is different from the past because the mental viewing has changed, not because somebodys clock rings. Daysseemed to last longerin your youth because the young mind receives more images during one day than the same mind in old age.

Overall somatic decline is ensured by similar physiological defects. New data published by researchers at Yale University revealed that our ability to obtain energy by burning belly fat also reduces as we grow older. This impairment is a direct cost of medical and agricultural preferments that have allowed us to defy our intended life expectancy.

Several mechanisms in the body are not selected for longevity,explained the papers lead researcher, Vishwa Deep Dixit. Normally the B cells produce antibodies and defend against infection. But with aging, the increased adipose B cells become dysfunctional, contributing to metabolic disease. This predisposes an animal to diabetes and metabolic dysfunction like inability toburn fat.

Thankfully, successful aging is no longer a consideration beholden to science fiction. Genetics may draft the treatment, but our lifestyle choices govern how gracefully we interpret the consequential beats. Presbycusis for instance (gradual degeneration of the cochlea consequenced by bilateral symmetrical aging) is by all accounts unavoidable. It is the leading cause of hearing loss and affects just about one and two individuals over the age of 75. However, there are cumulative environmental predictors that can worsen the condition and even accelerate its development. Prolonged exposure to headphone frequencies causes the hair cells in the cochlea to bend beyond the point of repair. Uniformly, we all have a reserve capacity of cells, each of which dies without fanfare throughout a given day.

Of course, as we age, this process, which is calledapoptosis, picks up momentum. What you might not know though is our state of mind mandates how quickly and violently this program transpires.

Having a good attitude is very important. We know that stress plays a key role in how we will age. We have these hormones, these stress hormones, that actually play a role in how our cells will die. When we become under stress we have an accelerated loss of cells. So this over a lifetime plays a major role in how functional we will be, explainedSteven Gambert, MD.

Even more consistently than this is the role our diet plays at the pace of our weathering. Diets like the Mediterranean, a regimen rich in vegetables and olive oil, low in meat ingestion, and moderate in alcohol consumption, slackens the agents of aging by checking their pawns, namely chronic maladies associated with old age. A recent study conducted on 23,349 men and women confirmed what previous literature had intimated in the years prior. Medical journalist, Caroline Wilbert reports:

During the study period, there were 652 deaths among 12,694 participants who had lower Mediterranean diet scores of 0-4 and 423 deaths among the 10,655 participants who had higher scores of at least 5. In general, those with higher scores were more likely to still be alive at the end of the study.

Similarly, earlier this year a team of European researchers disclosed that routine coffee consumption contributes to DNA integrity and overall longevity. This is earned by the antioxidants residing in dark roasted beans, a compound that helps cells repair themselves more effectively in the wake of the damage done by free radicals. Free radicals, birthed by sunlight, oxygen, and pollution, deteriorate the collagen fibers in the skin. The microbial properties in coffee help staff off these very same germs. Its caffeine acid boosts collagen levels which in turn brakes the aging process.

When it comes to confronting the aspects of aging that we cannot outwit, its important to distinguish a superficial fear of growing old, alternatively phrased as literal molecule deterioration, from a philosophical fear of death; the metaphysical cessation of being. Though Im not deaf to the terror of either, the attenuating of the former cant really refute the latter in and of itself. In other words, extending life for its own sake wont do you any good without some kind of moral equipment to boot. However you go about securing this is valid enough so long as it doesnt infringe on the fundamental rights of others. Rabelais lived for ambiguity, Plath was vitalized by the unreal and dangerous, Van Gogh was energized by lifes series of small things, Hitchens lived for irony (and died for it too), and Camus made a point not to think about any of it too intensely.

Chronological age is the most literal translation of our time here, our biological age is the most honest projection of how much of it weve got left, and our reservoir of purpose judges how successfully we spent it. Ultimately, appealing to your temple and the candles that emblazon it, is a good way to neuter the urge to cry over expired milk, whether the curtain falls when youre 25 or 98.

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Global Stem Cells Market Growth Driver 2016 2024: By Companies Osiris Therapeutics Inc., STEMCELL Technologies Inc., BIOTIMEInc., Celgene Corporation…

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Bats’ Ability to Combat Viruses and Control Inflammation Provides Insights in Fighting COVID-19 – Nature World News

Jul 17, 2020 09:10 AM EDT

The longevity of bats and their ability to combat viruses help them control inflammation, giving scientists insights on possible tools for combating COVID-19.

Bats have been implicated in many new and even older pathogens that afflict humanity. These include rabies, Ebola, and SARS-nCoV-2, which causes COVID-19. Bats have been observed to have remarkable resistance to these viruses. In addition, they have longer lifespans compared to similarly-sized mammals.

Researchers published an article in Cell Metabolism outlining bats' unique abilities and mechanisms and how they can help develop treatments for human diseases. The authors are biology professors Andrei Seluanov and Vera Gorbunova from the University of Rochester and the National University of Singapore Centre for Healthy Aging director Brian Kennedy.

The COVID-19 causative agent, SARS-nCoV-2, along with a host of other viruses, are thought to have come from bats, who serve as carriers; the bats themselves do not seem to develop disease from it. In addition, a lot of bat species have 30- to 40-year lifespans, which is unusual for their small size, since smaller animals tend to live shorter lives. Gorbunova says that the resistance of bats to infections may be connected to their long life. This could give clues on formulating human treatment.

The researchers' studies also showed inflammation's role in age-related illnesses and aging. Such diseases include Alzheimer's, cardiovascular disease, and cancer. Viruses such as COVID-19 can also cause inflammation. Gorbunova says that the inflammation may be the factor that kills COVID-19 patients.

Gorbunova says that the immune system uses inflammation and fever to fight viral and bacterial infections, but these responses can also overreact and pose a danger to the body itself.

Unlike us, bats have mechanisms that inhibit viral replication and dampen immune responses to viral infections. This causes an optimal bodily reaction, wherein the viruses are controlled with little inflammatory response.

The study authors say that various factors could be contributing to the evolution of bat disease resistance and longevity. The flight could be one factor since it lets bats adapt to rapid body temperature rise, molecular damage, and sudden metabolic surges. Such adaptations are useful in fighting disease.

The environment could be another factor. Dense and large bat colonies are the perfect venue for disease transmission. This constant exposure to viruses triggers bats' immune systems into always being active in a perpetual war with pathogens. Their immune system is always busy evolving mechanisms to combat new pathogens that regularly come in contact with them and their colonies. Gorbunova says that the strongest adaptive or evolutionary driver of disease resistance is a constant war against pathogenic organisms. Dealing with so many viruses, she says, could be developing better immunity and longer lifespans.

Such evolution develops over thousands to millions of years, and will not work for human adaptation to COVID-19. Only recently have humans congregated in congested cities or developed frequent world travel. Humans simply haven't evolved the complex mechanisms of bats. Gorbunova says our bodies may respond to such pathogens with more inflammation.

The study authors also think that aging may exacerbate the harmful effects of COVID-19 in humans. Gorbunova says the pathogenesis of the disease is different in the elderly.

The study authors think that the study of the bat's immune system will provide new therapies against humans aging and diseases. One possible research focus is the inhibition in humans of genes that cause inflammation; these genes have been eliminated in bats.

2018 NatureWorldNews.com All rights reserved. Do not reproduce without permission.

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The Future Of Style: Slow Fashion Plus … Merch Tees? – KPBS

Trista Roland, founder of San Diego pattern company Sugardale, discusses fashions post-pandemicfuture

Credit: Michael Armstrong

Above: Sugardale's founder Trista Roland works on a pattern in her studio in an undated photo.

I was still in the same leggings Id slept in the night before when I called Trista Roland, founder of Sugardale and part of San Diegos hand-sewn clothing movement. I tried to remember six weeks ago, deciding what nice but pinchy thing to wear to work, but it felt like something that had happened to another person.

I asked Roland who identifies more as a pattern designer than a dressmaker, though she makes and designs many of her own clothes what she's been wearing during the pandemic. She said she's been keeping it super comfortable, but it's hard to believe because her Instagram feed brims with flawlessly made outfits and a general, enviable put-together-ness. "I have gotten dressed up for shooting photos for Instagram and I'll just stay in those clothes all day," she admitted.

Sugardale's patterns are stylish but practical pants or skirts, with the option of overalls-, coveralls- or dress-style tops, each one a balance of playful and tailored, and each amendable and customizable. (And always with pockets. "It's a security thing," she said.)

Unlike much of the world adjusting to carefully displaying (or hiding) our work-from-home attire over video conferencing, the sewing and fashion communities have been sharing their outfits digitally on Instagram for years, and not all that much has changed for them. Opportunities for dressing up still exist, if you know where to look. Roland described "frocktails," an IRL meet-up where the local sewing community could get together and wear their own handmades, just to show them off. She added that frocktails have pivoted to Zoom. "It has been fun to just play dress up for no other reason, just to do it," she said.

When it comes to the pandemics longer-term impact on style, particularly womens fashion, Roland isn't really thinking about what people will wear to work; she looks at an even bigger picture.

The coronavirus pandemic has only just begun to spotlight systemic problems with working conditions and the global supply chain for all industries, Roland said, who studied in the fashion program at San Diego Mesa College about a decade ago and launched Sugardale several years later. We have a new societal understanding of the conditions and risks low wage earners go through to provide products and services, she said, and we're aware of the impact on the economy of the loss of these jobs. She thinks this will apply to fashion, too.

The "fast fashion" industry's impact on human rights and the environment is bleak. The standard set of seasons has morphed into some 52 "microseasons," for the fast fashion climate getting trends into stores as quickly as possible. Consumers are encouraged to constantly buy new items, as quickly made and cheaply made as possible, and discard their old things sending tons of synthetic fabrics and microplastics to the landfills. Global manufacturing waste and pollution present another problem.

For Roland, "slow fashion" embraces the opposite approach. "It's not even just the quality of the garment itself, but thinking all the way down the line: how it was made, where it was made. Was it ethical? Are the people working and making your clothes being treated ethically? Do they have good working hours? What is their working life like?" she said. "How does that garment get onto your body?"

In the slow fashion movement (and in the hand-made movement, which is an extension of slow fashion) care is taken in source, quality, process and longevity. There's a focus on capsule wardrobes, where slow fashionistas build multiple outfits out of a small collection of staples. It's not about constantly having the newest styles, but is about finding pieces that will work well for a long time.

Roland hopes that more people will turn towards making their own clothes, and thinks this may be a natural progression after so many individuals dusted off their sewing machines to try mask making. "You might have a bunch of people with a new hobby," she said.

As Sugardale grows, Roland is also hoping to help guide her customers to "hack" their own designs from her pieces. She's posting more tutorials online and will launch a Patreon-style subscription service in the coming months.

Roland pointed out that theres one unique way people are still buying clothes right now, despite not having anywhere to wear them. With coffee shops, restaurants, bars, bands and more all shut down or doing limited work, many are offering merch for sale online to stay afloat. She said that with an increasingly grassroots approach to where their money goes, people are doing what they can to support their favorite businesses. Unlike slow fashion, merch shirts are not always about the quality of the product, but they mark a greater focus on the people and work the consumers want to support, Roland noted, which is still a form of using fashion to support workers.

"Maybe that's what'll happen," Roland said. "We'll all be in jeans and logo'd shirts at the end."

KPBS' daily news podcast covering local politics, education, health, environment, the border and more. New episodes are ready weekday mornings so you can listen on your morning commute.

Julia Dixon Evans Arts Calendar Editor and Producer

I write the weekly KPBS Arts newsletter and edit and produce the KPBS Arts calendar. I am interested in getting San Diegans engaged with the diversity of art and culture made by the creative people who live here.

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Worst-case scenarios arent the only ones – Keizertimes

In February, the Centers for Disease Control and Prevention held a conference call on COVID-19 and warned, as The New York Times reported, that 160 million to 214 million Americans could become infected and 200,000 to 1.7 million might die.

On March 3, the World Health Organization noted that globally 3.4 percent of those infected with the virus died.

These numbers have become frequent talking pointseven though they presented an inflated picture based on cases confirmed because patients had symptoms in countries with dubious health care systems. We are living in a news climate where the scarier the factoid, the more credibility it can claim.

The problem is the experts dont know this number either, Stanford University Medical Professor Jayanta Bhattacharya told me after he became alarmed at some of the high estimates floating around including numbers that, for example, didnt factor in the effects of social distancing.

And it bothers Bhattacharya that risk assessments see risk only in not following guidelines when there can be risk in following them. Theres mortality on both sides of this, he explained.

I am not an expertso Ill go along with what doctors recommend. But I can still voice skepticism about dire predictions that the nation has to hunker down for many months, and I can wonder if a multimonth shutdown, which some officials are suggesting, will produce economic outcomes that are bad for human health and longevity.

And Im open to news that doesnt offer the worst possible information.

As of last week,the mortality rate in the United States was about 1.5 percentwith a patient pool that largely was symptomatic. Dr. Anthony Fauci told Congress he believes the coronavirus mortality rate is 1 percent10 times larger than the 0.1 percenet rate for the common flu.

Bhattacharya sifted through studies, corrected for certain factors and came up with morality rate closer to one-half of 1 percentbut he wont trust that estimate until there is a study to back it up.

Thats not great news, as it portends once-healthy adults hooked up to ventilators and vulnerable people in caskets. Wed all like the magic number to be zero.

The death rate stays on the low side only if health care workers have protective gear and hospitals have beds and ventilators and that is not a universal situation.

I am struck at one area of agreement between Trump and New York Gov. Andrew Cuomo.

Trump told Fox News that his goal was to ease the guidelines and open things up to very large sections of our country as we near the end of our historic battle with the invisible enemy. Trump threw out Easter, April 12, which he later called a beautiful timeline. Figure, its a goal.

University of Ottawa professor of Law and Medicine Amir Attaran told The Times, Nobody voted in Donald Trump thinking he would become a one-man death panel empowered to dispense with American lives like cannon fodder.

For his part, Fauci told reporters that no one wants to tone things down in New York City but there could be a more flexible approach in parts of the country.

Cuomo, the governor of the state with the countrys worst infection rate, has spoken to the same effect. He told reporters, You cant stop the economy forever. Cuomo has flirted with sending young people or those who have had the virus and are now immune back to work earlier than others.

Presumptive Democratic nominee Joe Bidens reaction to Trumps Easter talking point?

The former vice president told CBS News: The only thing we can do worse than telling the American people the truth is in fact raise false hopes. And then when it doesnt occur, they say, oh my God, something really must be worse than I thought it was.

Thats the conventional wisdom from inside the Beltwaythat there is a duty to shut down everything because there is no downside to an abundance of caution. And somehow leaders instill trust by not wanting to open some of the doors sooner.

Theres no caution on either side, said Bhattacharya. If the end of the quarantine is tomorrow, that could be a disaster. If we continue the quarantine for a couple of months, that could be a disaster also.

(Creators Syndicate)

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Successful Aging: Focusing on the wide-ranging contributions of older Americans – LA Daily News

Dear readers,

Its time for a celebration. May is Older Americans Month, a time to celebrate older Americans for their past and current contributions to society.

The formal recognition of older Americans began with President Kennedy in 1963 when he designated May as Senior Citizens Month during a meeting with the National Council of Senior Citizens. That was when only 17 million Americans reached their 65th birthday in comparison to almost 50 million today. About one-third of those 17 million lived in poverty with few programs to meet their needs. Two years later, in 1965, President Lyndon B. Johnson passed the Older Americans Act and formally declared May as Older Americans Month.

Each year there is a theme. This years theme is Make your Mark, selected to encourage and celebrate the countless contributions older adults make to our communities. Here are some highlights of those contributions.

Older adults as volunteers: Older adults are volunteers. Almost one out of four older adults volunteer in some capacity, which translates to 1.9 billion hours of services worth $45.5 billion of contributed services. The U.S. Bureau of Labor Statistics listed the median annual volunteer service hours for all ages as 52 hours per person; for those 65 and older, the median was 96 hours. Older adults volunteer as a way to give back, making a difference in their churches, organizations, communities and wherever there is a need.

Older adults with encore careers: An encore career typically occurs after ones primary career and before what we consider traditional retirement. It is a career that embraces purpose, passion, sometimes a paycheck and giving back to make a difference. Giving back is a distinguished aspect. A study from several years ago found that 5.3 to 8.4 million people between the ages of 44 and 70 had an encore career, working in education, health care, government and nonprofit organizations. Of those within that age group not already in an encore career, half said they were interested in one.

Older adults as caregivers:Manycaregiversofolder peoplearethemselves older adults. According to the National Alliance for Caregiving, 70 percent of adult children are caring for a parent ages 50 to 64 years. Some caregivers are even older. A typical much older caregiver is almost 79 years old, white, female and typically cares for a close relative who is 77 years old. This older caregiver provides 34 hours of care per week for five years. She is the sole unpaid care provider for her loved one.

Older adults as age advocates: Older adults also advocate for themselves and causes for social justice. Betty Friedan not only advocated for the advancement of womens rights but also for older women when she wrote The Fountain of Age published when she was 72 years old. Author and activist Ashton Applewhite at age 68 leads a movement to abolish age discrimination. Her book, This Chair Rocks: A Manifesto Against Ageism is written to do just that.

Older adults as movement builders: At the age of 77, John Sorenson, a former CEO, created the Elders Action Network, a movement of elders to address the social and environmental crises of our time. The foundation of his work is the belief that we are wasting an invaluable human resource that could be applied to problems facing our nation. The Network focuses on climate action, sustainable living and social justice. A subgroup of the network is the Elders Climate Action with 3300 members, a non-partisan movement of elders committed to making their voices heard to change national policies to void catastrophic changes in the earths climate.

Older adults as contributors to our economy: In 2018, those 50 years and older contributed $8.3 trillion dollars to our economy. In terms of gross domestic product, that places older adults contribution as the worlds third-largest economy just behind the U.S. and China. We earn and spend money; we generate tax revenue, give to social causes and create demand for products and services that stimulates growth. We have created the longevity economy.

In this trying time, lets celebrate us. We collectively made our mark yesterday and today. I am certain, we will continue to make our mark for our many tomorrows.

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The New Thermaltake CyberChair E500 – Hardware – Press Release – HEXUS

Taipei, Taiwan April 1st, 2020Thermaltake,a leading brand in PC DIY for cooling, gaming gear, and enthusiast memory solutions, proudly presents thefirst ergonomic chair CyberChair E500.An ergonomic chair is always the best choice when it comes to users who are required to sit for long hours, and the Cyber Chair E500 could be the new best choice. The CyberChair E500 is made of permeable mesh cushioning that is highly breathable, and the back structure is built with robust aluminum to extend its longevity while providing sturdy support to the human backbone. The CyberChair E500 offers high adjustability ranging from the headrest, seat depth, height adjustment, and wire-control mechanism with multi lockable positions to reach maximum comfort. Furthermore, users can relax and immerse the body with up to 117 degrees of back angle inclination. Aside from the extensive sitting positions focusing on the neck and back, the CyberChair E500 also provides multidirectional armrests that are adjustable in height and width to relieve wrist pressure and muscle strain of the forearms. Finally, the CyberChair E500 is constructed with a 5-star aluminum base, its sturdy framework is designed to support a max load of 330 lb (150 kg), with 3 wide large caster wheels that further enhances the stability whilst providing quieter operation and more significant movement.

Features of the ThermaltakeCyberChair E500:

Durable high tensile mesh

CyberChair E500has a highly breathable mesh surface with a soft touch that is easy to clean. Thermaltakes mesh surface had passed the SGS 100,000 impact fatigue tests and the California Technical Bulletin 117 flame resistance test to ensure users safety.

Headrest Adjustment

The adjustable headrest allows users to modify the height of the headrest to match the users head posture. Moreover, the front side rotation mechanism can hold the users heads from different angles.

Elastic Ergonomic Backrest

Constructed by two compartments, the upper part of the backrest aligns with the headrest providing promising head to back alignment, along with the lower part of the backrest, which is an elastic compartment that fits perfectly with the lumbar spine and all types of body shapes.

Height Adjustment

Seat height ranges from 500 mm to 600 mm (19.6 to 23.6 inches); class- 4 gas lift provides steady and secure seat height adjustments.

Elastic Control

On the right side of the Cyber Chair E500, users can twist the elastic handle to adjust the resistance feedback from the backrest, ensuring users with different weights can smoothly and safely adjust the seating angle.

Seat Depth Adjustment

The adjustable sliding seat base can travel 30 mm when the sliding mode is turned on. It can be adjusted synchronously with the tilt angle of the backrest to provide a greater rest angle for the body and create the most comfortable reclining angle in a limited amount of space.

Adjustable Backrest

The Cyber Chair E500 provides an excellent back angle tilt from 90 degrees to 117 degrees, which allows the users to adjust the backrest as needed.

Stiff Aluminum Alloy Back and Base

Using the aluminum alloy integral molding method, the CyberChair E500 brings durability, sturdiness, and elegancy to the users, and the heavy-duty 5-star aluminum base measures 700mm (27.5in) in diameter and weight support up to 150kg (331lb).

Availability, Warranty, and Pricing

Thermaltake CyberChair E500 ergonomic chair will be available for purchase in April 2020 via the Thermaltake worldwide network of authorized retailers and distributors. It is backed by a two-year warranty and supported by the Thermaltake worldwide customer service and technical support network. For up-to-date pricing of the chassis, please refer to the Thermaltake website or contact your local Thermaltake sales or PR representative.

For more details on ThermaltakeCyberChair E500 Ergonomic Chair, please visit:

https://www.thermaltake.com/cyberchair-e500.html

Where to Buy:

CyberChair E500 ergonomic chair on TT Premium

TT Premium Australia https://ttpremium.com.au/product/ggc-eg5-bblfdm-01/

TT Premium Taiwan https://ttpremium.com.tw/product/ggc-eg5-bblfdm-01/

TT Premium China https://ttpremium.com.cn/product/ggc-eg5-bblfdm-01/

TT Premium Asia https://asia.ttpremium.com/product/cyberchair-e500/

Thermaltake official website and community websites:

Thermaltake official website:

http://www.thermaltake.com

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Thermaltake Technology was established in 1999, and has been marketed to the world under the Thermaltake brand name ever since. Thermaltake first specialized in air cooling, successfully launching the worlds first turbine cooler, the Golden Orb. With the mission to Deliver the perfect user experience,Thermaltake has since then become the leading brand in computer hardware & peripherals in thePC DIY marketand the number one choice forPC DIY enthusiastsworldwide.

Key 3 stands for Thermaltakes 3 main product lines:case, power, and cooler. Thermaltake started with cooling products, and with time branched into case and power supplies. Thermaltakesinnovationhas allowed the brand to createunique, aggressive, vivid, and stylishproducts. With strengths in innovation and complete product lines, Thermaltake ventured into thecasemodmarket to providemodderscasemod total solutions.

The Key 3 Spirit represents Thermaltakes promise toward its users; the promise to provide products that displayQuality Performance & Reliability. The Key 3 Spirit is the foundation for all Thermaltake products, and is the reason for Thermaltakes continuous success worldwideOfficial website :www.thermaltake.com

About TT Premium

TT Premium.com, the most comprehensive liquid-cooling and modding online shopping experience. The platform is designed to provide exceptional high-end products and services to customers worldwide.Thermaltake TT Premiumincludes several case modding products that support VR (Virtual Reality) gaming systems.Thermaltake TT Premiumis the best high-end liquid cooling and case modding solutions shopping platform that provides client-tailored services and secure processing, to meet all user expectations. All products follow Thermaltakes core values of Excellent Quality, Unique Design, Diverse Combinations, and Boundless Creativity.Thermaltake TT Premium has expanded its footprint to over 100 countries and territories by creating a seamless network connecting 5 major markets; the United States, Europe, Australia, Taiwan, and China of seamless networking.

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The New Thermaltake CyberChair E500 - Hardware - Press Release - HEXUS

These companies are racing to roll out COVID-19 treatments – WICZ

By Paul R. La Monica, CNN Business

Big Pharma companies and biotechs are racing to come up with an effective treatment for the Covid-19 novel coronavirus.

Several high profile companies are working on new experimental vaccines. Drug giant Johnson & Johnson is the latest to announce a promising vaccine candidate, saying on Monday that it plans human testing by September with the hopes of having more than one billion doses of a vaccine available for emergency use by early 2021.

J&J said it was partnering with the Biomedical Advanced Research and Development Authority (BARDA) of the U.S. Department of Health & Human Services to produce the vaccine. Shares of J&J surged nearly 7% on the news Monday.

Many other companies are also working on vaccines, including small biotechs Moderna, Novavax and Inovio as well as Big Pharma firm Pfizer, which is partnering with Germany's BioNTech.

Shares of Moderna, Novavax, Inovio and BioNTech have all soared this year, even as the broader market has plunged due to worries about the impact of the coronavirus on the global economy. (Pfizer is down nearly 20%.)

But making and testing new vaccines may not wind up being the fastest way to treat Covid-19, says Sergey Young, founder of the Longevity Vision Fund -- a firm that invests primarily in smaller private biotechs.

Some firms are hoping that existing medications for other infectious diseases and immunological disorders can be used to tackle the global pandemic.

"This is the first time in history where companies are trying to repurpose drugs this fast, and that is exciting," Young said. "A vaccine is in the more distant future. We pray that one can come by the autumn."

Young pointed to three drugs in particular that might wind up being effective in treating symptoms of Covid-19. The first -- and the one that has gotten the most attention -- is remdesivir, a drug made by Gilead Sciences that was originally used for Ebola and other highly contagious diseases.

Officials at the World Health Organization have touted remdesivir as having the most potential to effectively treat coronavirus patients. The WHO has begun clinical tests of the drug on patients in Spain and Norway.

"Remdesivir is still an investigational medicine. We are planning for the outcome we all hope for -- that it will prove to be a safe, effective treatment -- and in the meantime we are taking the ethical, responsible approach to determining whether that is the case," said Gilead chairman and CEO Daniel O'Day in an open letter released Saturday.

Longevity Vision Fund's Young added that two other medications could be helpful in treating coronavirus as well: the HIV medication Kaletra, which is produced by AbbVIe and is a combination of the antiviral drugs lopinavir and ritonavir; and Kevzara, and a rheumatoid arthritis treatment made by biotech Regeneron and European drug titan Sanofi. (The reporter of this story owns shares of AbbVie.)

Sanofi is also working on a vaccine with BARDA funding from the US government.

Meanwhile, Chinese health officials have also been testing another rheumatoid arthritis drug -- Roche's Actemra -- on Covid-19 patients.

The hope is that one or more of these existing medications will help alleviate the worst symptoms from the coronavirus, buying more time for companies developing vaccines to come up with a longer term solution to stop the spread of the disease.

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These companies are racing to roll out COVID-19 treatments - WICZ

Nazgul & Dementors: 5 Things They Share (& 5 Ways They Are Completely Different) – Screen Rant

Both the Harry Potter universe and Tolkien's legendary The Lord of the Rings are replete with entities of the vilest nature -- magical creatures that do not fit into the human range of consciousness.

RELATED:Harry Potter Vs Frodo Baggins: Who's The More Heroic

The Nazgl are the Ringwraiths, some of the most powerful servants of the Dark Lord, Sauron. They have a major role to play as they hunt for the Ring and go after the Fellowship of the Ring and Frodo Baggins, the ring-bearer. On the other hand, the dementors are nasty, dark creatures that act as prison guards at Azkaban, the wizard prison in the Potterverse.

Let us see the ways in which they are similar and how they differ from each other.

The dementors, too, are wraithlike creatures, hooded with no concrete physical form. They are more like dark shapes, to be precise. In terms of appearance, the Nazgl and the dementors are quite similar in that both are dark, formless shapes that ignite fear in peoples hearts.

RELATED:The Lord Of The Rings: 10 Of The Worst Things That Happened In Middle Earth (Besides Sauron)

Dementors, on the other hand, look like decaying corpses and were never humans in the first place. They are, Rowling says, one of the foulest creatures to walk the earth, inhabiting some of the darkest, filthiest places. The absence of anything remotely human in them is one of their defining traits. Being non-humans, they also never had a physical form, unlike the Nazgl.

The Nazgl are the most terrible servants of Sauron, the primeval dark force that presides over Mordor, and plan to take over the whole of Middle Earth, in Tolkiens epic fantasy universe. These are dark entities whose souls have been tarnished by the extraordinary power of the Rings and their fate is now bound to that of Sauron.

RELATED:Harry Potter: 10 Hidden Details About Dementors You Probably Missed

The Nazgl, though, having been humans once, require the use of actual physical weapons to fight their enemies. They are shown to be using daggers, swords and terrifying maces. Although they are invisible to those who cannot see into the wraith world, their past history as men makes it imperative that they carry weapons.

Similarly, the dementors, as the name suggests, are symbols of gloom and despair, leaving a person without a happy thought. They feed off happiness and their arrival drowns people in the depths of depression. The more they feed the more their numbers multiply, making them some of the most hated, disgusting and terrifying creatures in the wizarding world.

RELATED:Lord of The Rings: 10 Best Quotes From The Return of The King

The dementors, in the Harry Potter universe, are innumerable and nowhere does Rowling state whether or not they can die and if so, how. One can assume that since they feed on human happiness, they might also rot away if they are not able to feed. But this is pure conjecture since Rowling never actually mentions whether dementors have specific longevity, or for that matter if they can be killed.

The dementors presence, although not poisonous per se, can be felt from quite a distance. The victim feels a sweeping sensation of cold as the dementor approaches. The feeling precedes the dementors arrival and is capable of turning water into ice. Both entities bring with them a sense of doom and overwhelming horror.

RELATED:Lord Of The Rings: Members Of The Fellowship, Ranked

The dementors, however, are not bound to anybody elses fate. Although they chose to ally with Voldemort in the final battle, they are not necessarily servants to You-Know-Whos whims. It is said that they go where they can feed the most, so it is safe to assume that they owe no loyalty to anyone. While the Nazgl serve the Ring and Sauron, the dementors as such serve no-one in particular.

Similarly, the dementors, as Potter fans know, disperse at the sight of pure happiness. The Patronus charm that is used to get rid of them is nothing but concentrated happiness of the purest kind. The blinding Patronus created from a happy memory scares the dementors away.

Unlike these winged wraiths, however, the dementors are never seen traveling on mounts. They are floating creatures that were never human and hence do not need mounts, winged or otherwise, to carry them.

NEXT:Harry Potter: 10 Hidden Details About The Cupboard Under The Stairs You Never Noticed

Next10 Low Budget Sci-Fi Movies That Are Better Than Blockbusters (& Where To Stream Them)

Surangama, or Sue, as she is called by many, has been writing on films, television, literature, social issues for over a decade now. A teacher, writer, and editor, she loves nothing better than to curl up on a lazy afternoon with her favorite book, or with a pen and a notebook (a laptop would have to do!) and a foaming cuppa tea on the side.

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Nazgul & Dementors: 5 Things They Share (& 5 Ways They Are Completely Different) - Screen Rant

Doing business in the time of COVID-19 – CanadianManufacturing.com

March 17, 2020by Alanna Fairey, Associate Editor

PHOTO: Getty Images

Since December 2019, the world has been closely following the news of the coronavirus, and while the impact on human health has been significant, its also taking a toll on small and large companies all over the world who are planning for contingencies and trying to make sense of the virus.

According to Export Development Canada (EDC), the challenge to the global economy and Canadian exporters ultimately depends on the severity and longevity of COVID-19.

EDCs webinar, Coronavirus (COVID-19): Managing the impact on global supply chains, hosted on March 11, provided insight on how Canadian exporters can be prepared to take on the risk of doing business in rapidly changing international markets and what services EDC can offer.

Moderated by Dominique Bergevin, EDCs manager of commercial markets and small business, the panelists included vice-president and chief economist Peter Hall; senior account manager of commercial markets & small business, Amira Dali; and bank channel director, Rajesh Prashadcolah.

With COVID-19 impacting the global supply chain, Hall stressed that it is important for businesses to have contingency plans in place for key suppliers for liability purposes.

This may include reviewing some of the existing terms and conditions with your customers, your suppliers and ensuring that the language will protect you from future events, Hall said.

When it comes to suppliers, most people think both companies are providing you the raw materials are equipped to ensure operation, but a key supplier can also be your banker advisors.

Added Hall: Its important to have these conversations with their partners in advance.

While the significant decrease in numbers has many feeling fearful of a recession, Hall said that this will not be the reality in the long-term.

The key message here is that there is a limit to the duress, and there is a limit to duration and thats not what the popular medium is generally playing on my channel. Its very much about fear, Hall said.

For her part, Dali stressed that it is important to have risk management systems that encourage businesses to be proactive rather than reactive to the hurdles that COVID-19 is imposing.

Risk management strategies should be made of four segments which include: risk avoidance, risk sharing, risk reduction and risk transfer.

Dali also said that is essential for exporters to have insurance plans set up and to have conversations with financial partners prior to a pandemic to understand what financing options are best available.

No matter what industry that youre in, theres a resource available out there, starting with your trades and missionaries, Dali advised. The Trade Commissioner Service is a great starting point, whether locally or whether internationally.

While the repercussions of COVID-19 were events that could not have been foreseen, Hall concluded the webinar by reminding viewers that the experiences of COVID-19 can help them make plans for their business and their third parties moving forward.

Having contingency plans in place for key suppliers and customers will help mitigate some of that and this may include reviewing some of the existing terms and conditions with your customers, your suppliers and ensuring that the language they will protect you from future events, Hall said.

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Doing business in the time of COVID-19 - CanadianManufacturing.com

Last Nights on Londons Stages, Before the Lights Went Out – The New York Times

LONDON Nol Coward wrote Blithe Spirit in a mere six days, and the perennially popular play opened on the West End in 1941, running for nearly 2,000 performances setting a record in London for a nonmusical.

Its longevity back then is in stark contrast with the most recent outing of the play here, with Jennifer Saunders, of Absolutely Fabulous fame, playing the bicycle-riding medium Madame Arcati, who communicates with the dead. A victim of circumstances beyond the control of even the most supernaturally minded, the director Richard Eyres comparatively somber revival played its last performance at the Duke of Yorks Theater on March 14; the run had been due to finish on April 11.

The production closed early after Londons West End theaters took coordinated action on Monday to close themselves down and help stop the spread of the coronavirus. Londons West End, like Broadway, has gone dark, and no one knows when the lights will come back on.

As premature closings go, the timing here was somewhat ironic, when you consider how audiences throughout World War II flocked to Blithe Spirit, Cowards inquiry into the frustrations, erotic and otherwise, of Charles (Geoffrey Streatfeild), a novelist whose first wife returns from the grave. (She died, were told, while recovering from pneumonia, which may well have had an eerie resonance for nervous playgoers today.)

When she rises up, the mischievous Elvira (Emma Naomi) scatters calculated chaos in her wake. Its giving nothing away to tell you that she ends up taking Charless second wife, the whiplash-tongued Ruth (Lisa Dillon, giving the performance of the night), over to the other side with her, though neither woman will go quietly from the land of the living.

This was easily the least buoyant Blithe Spirit Ive seen, which was presumably intentional on the part of Eyre, the distinguished director who once ran the National Theater. The trend of late has been to find in Cowards outwardly breezy plays something more psychologically acute, as was the case when Andrew Scott, of Fleabag fame, stormed the Old Vic last summer in Present Laughter. Against expectation, a character long presented as a devil-may-care narcissist was revealed to be an anxious man-child, as well. Both revivals remind us that Coward possessed a keen understanding of human behavior, in addition to a quick wit.

In this Blithe Spirit, Charles and Ruths marriage seems far from blissful well before Elvira arrives on the scene, and Eyre takes the verbal brickbats they lob at each other for real. This, like Present Laughter, is a Coward play centered around a man who draws women to him when he would rather be left alone: Both plays end with their flustered heroes fleeing female companionship, but for what precisely? Coward leaves the sequels up for grabs.

The fate of this show, however, is sealed though no one could have guessed how quickly it would flit from view. Think of the cast as the casualties of an invisible terror. It was one that Saunders, top-billed albeit in a supporting role that Judi Dench is playing in a forthcoming film, acknowledged when Madame Arcati a germaphobe before her time reacted in spontaneous disgust at shaking another characters hand. I doubt those who laughed at that gesture last week would do so now.

Across London last week, a city in gathering distress was met with theater that chimed with the prevailing mood. Before the shutdown, I caught what turned out to be the final matinee of Shoe Lady, an arrestingly quirky play from E.V. Crowe at the Royal Court Theater, best described as a surrealist nightmare in the style of Caryl Churchill.

Its like were all on the edge, says Viv, a realtor whose life goes into free-fall when she loses a shoe on the London Underground. Buck up, she says, all the while succumbing to a growing sense of anxiety, brilliantly captured by Katherine Parkinson, accentuating her characters panic the more determinedly she keeps smiling. Running just over an hour, Vicky Featherstones production cant have anticipated how much the play, which might otherwise have seemed a theatrical caprice, felt instead like a parable of precariousness in a society that, much like Viv, seems to be losing its grip.

The connection between life and art was even more keenly felt on Monday at the Southwark Playhouse, in southeast London, one of the few theaters to offer a show on the evening when the bigger houses around town were calling it quits.

There, I was among a surprisingly full house to catch the last performance of the director Jonathan OBoyles hyper-intense revival of The Last Five Years, the Jason Robert Brown musical about a couple falling apart. (Think of it as the Marriage Story of the early 2000s.) The conceit of a show that alternates perspectives across 90 minutes is that one character, Jamie (the excellent Oli Higginson), tells his version of events from the beginning, whereas his ex, Cathy (Molly Lynch), begins her version of events at the end.

But there was no doubt for those in the room that we were all witnessing a finish of a different sort, given that it is entirely unclear when any of us will find ourselves in a London playhouse again. The audience that night had seemed especially focused, as if everyone present was savoring for keeps the experience of live performance.

Taking an empty Underground train home, I couldnt help but feel that Jamie and Cathys unraveling had acquired a resonance well beyond what the composer-lyricist Brown could have imagined. I wont soon forget the surge of feeling throughout the auditorium when the show got to its closing sequence, and ended on a single word: Goodbye.

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Last Nights on Londons Stages, Before the Lights Went Out - The New York Times

Half of Workers Aren’t Accounting for This Massive Retirement Expense – The Motley Fool

There's a lot to think about as you're preparing for retirement. Not only do you have to consider how much you should save by the time you retire, but you'll also need to plan for how you'll spend all your time, how much you'll be receiving in Social Security benefits, and more.

But there's one factor that many workers aren't accounting for as they're planning for their senior years, and it can potentially cost you tens or even hundreds of thousands of dollars.

Image source: Getty Images.

Nearly half (48%) of workers say they haven't accounted for healthcare expenses in their retirement plan, a report from theTransamerica Center for Retirement Studies and the Aegon Center for Longevity and Retirement found. Of those who aren't planning for this expense, nearly 30% admitted it's because they simply never thought about it before, while 26% said they expect the public healthcare system to take care of their expenses.

If you're not preparing for healthcare costs in retirement, you could be in for a costly surprise. Even with Medicare coverage, you'll still be responsible for certain expenses, including premiums, deductibles, copays, and coinsurance. These costs can add up, too. In fact, the average retiree spends around $4,300 per year on out-of-pocket healthcare costs, according to a study from the Center for Retirement Research at Boston College.

This number also doesn't include costs associated with long-term care -- which can be one of the most significant expenses you'll face in retirement. Approximately 70% of today's retirees will need long-term care eventually, according to the U.S. Department of Health and Human Services, and those who do need this type of care require it for an average of three years.

If you do end up needing long-term care, you can expect to spend a good chunk of change. The average semi-private room in a nursing home costs more than $6,800 per month, and if you end up spending three years in a nursing home, that comes out to nearly $250,000 on long-term care alone. In addition, Medicare typically won't cover long-term care, so you'll be left to foot this massive bill out-of-pocket.

All of these expenses can take a huge bite out of your retirement fund, so the more you can prepare for them ahead of time, the better off you'll be.

It can be challenging to prepare for medical expenses because nobody knows exactly how much care they'll need in retirement. You may never need long-term care and can get by spending only on Medicare premiums and other routine costs, in which case your healthcare expenditures will be minimal. Or you may develop costly health problems and may end up needing several years of long-term care, which could lead to hundreds of thousands of dollars in out-of-pocket costs.

Although you can't prepare for every expense you'll face, it's a good idea to plan for everything, just in case. First, think about how much you'll be paying for Medicare coverage. Original Medicare consists of Part A and Part B. Retirees typically won't pay a premium for Part A coverage, but you will face a deductible of $1,408 per benefit period. For Part B, the standard premium is around $144 per month and the deductible is $198 per year.

Keep in mind, however, that Original Medicare does not cover routine dental or vision care (which includes teeth cleanings, fillings, yearly eye exams, prescription glasses, etc.), nor does it cover prescription drugs. For this type of coverage, you'll need to enroll in a separate plan such as Medicare Part D or a Medicare Advantage plan -- which will be an additional cost.

To prepare for long-term care, you have a couple of options. First, you could sign up for long-term care insurance. This type of insurance could greatly reduce the amount you'll pay out-of-pocket if you end up needing long-term care, but it can be pricey -- especially the longer you wait to sign up. The average 55-year-old couple can expect to pay around $2,500 per year in premiums, according to the American Association for Long-Term Care Insurance, but the older you are when you sign up, the more you'll pay.

Another option to help pay for medical expenses is to start saving in a health savings account (HSA). A HSA is similar to a retirement account in that you can invest your money, let it grow for years, then withdraw it during retirement. However, there are extra tax benefits with an HSA: Not only are your contributions tax-deductible upfront, but your withdrawals are also tax-free as long as the money goes toward medical expenses.

Healthcare expenses certainly aren't the most exciting aspect of retirement, which makes them easy to overlook as you're planning. But if you don't account for these costs, it could come back to hurt you later. By preparing the best you can now, you'll ensure healthcare expenses won't catch you off guard.

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Half of Workers Aren't Accounting for This Massive Retirement Expense - The Motley Fool

What Jason Hope Says About New Longevity Research – HealthTechZone

Throughout the past decade, various topics related to stem cells have made headlines across all platforms. From being hailed as the most innovative method for eradicating specific diseases, to being protested by various groups and organizations, the use of stem cells has gained national attention repeatedly. With promising initial scientific findings, and avid researchers aiming to solidify the presence of stem cell usage in the realm of science on a normalized basis, increasing numbers of startups, biotech giants, and independent companies are forging ahead with stem cell-related projects. As global connectivity, technological advancements, and the marriage between medicine and technology continues to evolve swiftly, Jason Hope sees stem cells will undoubtedly remaining in the spotlight.

Over 20 years ago, scientists successfully extracted the first human embryonic stem cells, and effectively grew these cells in a lab setting. The remarkable feat of being able to successfully grow the parent cells, which essentially allow for the growth of new cells in the body, was a hopeful moment for the medical sector involved in creating effective regenerative treatments for conditions like heart disease, Alzheimers, stroke, and Parkinsons Disease. Using basic reasoning, the successful regeneration of parent cells could provide the regeneration of undesired cells, leading to anti-aging results, or effective care for many age-related conditions that deteriorate the body over time.

Though this initial breakthrough was promising, the scientific community has not yet made significant strides in bringing stem cell therapy to market in a way that is well-researched, backed by medical associations, and commonly accepted by the scientific community. In fact, the only readily utilized stem cell treatments are related to successfully growing blood cells from matching donors for patients with various blood disorders. According to entrepreneur, philanthropist, and expert in the realm of anti-aging and longevity, Jason Hope, these initial utilization of stem cells are commendable, but require a lot more research in order to maximize the potential widespread benefits of stem cells in medicine.

Hope, who has devoted much of his philanthropic endeavors within the medical industry via groups like the SENS Organization, recognizes that most stem cell implementations are rightfully considered experimental until appropriate research, testing, and development can occur. As an expert in the realm of anti-aging, and the championing of increasing health throughout a lifetime, Jason Hope recognizes the potential distrust that can be formulated by the general public as a result of eager companies making lofty claims or promoting potentially faulty treatments not yet fully vetted by the medical community. Thus, while he remains avidly enthralled by the potential maximization of stem cell therapies, hope supports the long-term research needed to safely, successfully, and effectively generate breakthrough stem cell treatments.

Providing continued backing for the extensive research completed at the SENS (Strategies for Engineered Negligible Senescence) Organization, Hopes contributions aid in the research aiming to create preventative treatments for degenerative diseases and utilizing breakthrough science to increase the overall long-term quality of life for individuals. Instead of focusing on the treatment of symptoms and the disease throughout the progression of the condition, the scientists at SENS work to examine ways to successfully prevent the disease from happening. Through this boundary-pushing work, a lot of their research focuses on stem cell intervention. According to Hope, stem cell treatments for Parkinsons Disease are now in the second stage of clinical trials at SENS. While the process of undergoing such extensive trials may appear slow, it is crucial to maintaining overall public support via successful treatment launches and promising in terms of the long-term possibilities linked to stem cell treatments.

In addition to the research being conducted by SENS, preliminary medical studies are being conducted with a myriad of uses for stem cells. Experimental stem cell transplants of retinal cells were recently utilized in a small research study of macular generation, providing initially promising results for the handful of patients who have received artificially generated retinal cells. Elsewhere, scientists have begun to explore ways to minimize potential rejection of stem cells in organs like the liver, through maximizing the most conducive environment for stem cells to thrive. While these slow-moving vehicles of change are less prominent than startups promising the proverbial Fountain of Youth via experimental stem cell treatments, these medically sound research studies are forming the backbone of stem cell treatment for the future.

As with all scientific and medical innovations, Hope also recognizes the potential risks, hurdles, and roadblocks within the growing field of stem cell research, and integration into medicine. From supply chain concerns to potential long-term side effects, and the risk of overly eager startups making too-lofty claims, Hope understands that the road to the everyday utilization of stem cells remains lengthy and potentially bumpy. However, the proverbial juice may very well be worth the squeeze in this example. As stem cells harvest the potential power to overturn the degenerative effects of some of the most prominent diseases, allow individuals to maintain active health for elongated periods of time, and increase the quality of life for countless individuals, expanding upon the initial promising research is potentially a pivotal point for the medical community and humankind. Though the road to successful scientific integration of stem cells is long, the potential healthcare benefits are limitless, and according to industry experts like Jason Hope, worth investing in, exploring, and championing.

About Jason Hope

An avid entrepreneur, investor, and philanthropist, Jason Hope is a futurist involved in the championing of technological advancement, community involvement, and innovative medical interventions. Deeply passionate about the anti-aging, longevity, and human advancement niche of biomedicine, Hope remains actively involved in various scientific organizations.

After receiving a degree in Finance from ASU, and a subsequent MBA from ASUs W.P. Carey School of Business, Hope developed a successful mobile communications company. Professionally, he currently focuses on investing in startups and developing grant programs for small businesses.

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What Jason Hope Says About New Longevity Research - HealthTechZone

What is human centred AI and how can it impact business performance? – ITProPortal

Artificial Intelligence (AI) and Machine Learning (ML) arent new, in fact mechanical automation has been around for decades so why is there still an incredibly slow adoption rate across modern-day workforces?

Although it might not have been called AI or ML until recent times, the world has been surrounded by examples of this technology from having an x-ray to taking out a mortgage. Its primary purpose is to exist to try and make things simpler, quicker and easier for people.

And yet, despite being present for nearly a century, the concerns that machines are going to take over the world or that theyre untrustworthy and will take everyones jobs remains the same today.

For years, businesses have been trying to outdo one another with revolutionary promises and yet theres still a lack of understanding of what AI and ML represents and how it can and cant drive an organisation forward.

Thats because theres still a lack of trust and its become apparent that many people are still reluctant to hand over the reins to a machine when confidence is low. Its something that isnt new for those who occupy the world of business intelligence because the industry knows how AI promises everything but doesnt always deliver. Uncertainty has ensued because automation hasnt quite solved initial problems, but at the same time no-one is being automated out of a job either.

A great example to truly highlight how this translates into business performance is by looking at online delivery brand, Amazon. This is an organisation that deploys hundreds of robots which have been simplistically coded to collect products off the shelf and not bump into one another which is the AI part.

And the same concept can be applied in business. For example, if a person has applied for a bank loan within the last 20-25 years, its unlikely they will have had their initial query dealt with by a human. It will have been digested by a machine an algorithm that categorises individuals alongside others who have similar attributes.

AI isnt magical but it can collate large volumes of data by the second, which is an obvious advantage for the fast-paced and heavily evolving economic climate.

So, it does pose the question of exactly how does human centred AI truly impact business performance?

For larger scale AI adoption, organisations must think outside the box and perhaps onto the tennis court. Yes, this maybe a strange path to take, but the sports Hawk-Eye technology system could provide some food for thought when analysing AIs success through a transparent lens.

Looking back to the days when John McEnroe would infamously contest huge calls with showmanship and bravado, Hawk-Eye today often limits those moments instead shutting down any questionable decision with critical evidence to back up the umpires call.

And the reason why many players and the crowd accept those crucial outcomes is because tennis hasnt black boxed its automation. Instead, every single person watching can see exactly how the decision has been made by the machine, which introduces a greater level of fairness and trust that wasnt there before.

Line judges provide the human element, but its the machine that augments their decisions. Now because its done so well, its become a part of the game alongside other sports.

However, where mechanical AI hasnt fared as strongly is the example of VAR recently introduced into the English Premiership. If anything, its riled footballing crowds up even more to voice their displeasure, all because the machines decisions arent being shared with them. What it has determined is a lack of trust from supporters and onlookers because they havent played any part in the final decision.

For human centred AI to have a true impact on an enterprises bottom line and adoption level, there must be observation points included something which business intelligence is built upon. Having machinery that allows customers to understand and see how decisions are being made can instil a vast amount of trust and willingness to have confidence in the detail it forecasts.

There isnt a crystal ball when it comes to knowing exactly how the business landscape is going to evolve day-to-day but having smart platforms that can consume key trends and marketplace developments can help to balance business risk and determine decisions more swiftly.

And when wrong conclusions are met, thats where humans or rather the observers come in to tweak and adjust the model so that the path is corrected, and danger is subsequently averted.

Think of Tesla and how its self-drive capabilities are truly innovative. But, it can still get things wrong and if the driver isnt prepared for that, the results could be catastrophic. However, where this manufacturer prevails is by utilising a smart screen which shows how its making decisions. As a result, the person behind the wheel understands when to trust the vehicle to take control, and when they need to intervene.

Again, the same can be said for organisations and their employees who become the observers. To begin to achieve success, the team needs the desired information from AI, in order to elevate their jobs, watch the machine in action and work side-by-side all of which comes via business intelligence.

Examining real-time activity, enterprises are in fact creating cockpits where humans can step in where needed and trust the machine to effectively understand the detail and make commercially savvy decisions all of which the customer sees too.

Everybody has a part to play in ensuring what technology works best for their business and automation should ultimately be embraced rather than feared. However, for there to a positive impact made on business performance, firms must firstly get their business intelligence right and continuously study its ML as a pre-requisite.

Simplify the tools, demystify the black box and provide smart intelligence that isnt magical, but can instil trust, transparency and longevity for organisations.

Ken Miller, co-founder and CTO, Panintelligence

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What is human centred AI and how can it impact business performance? - ITProPortal

Catherine Opie: ‘Beauty has to encompass more about the human condition’ – CNN

Written by Catherine Opie

Beauty is often thought of in relation to fashion and femininity. Its construct in pop culture is something that I've always tried to work with in different ways in relation to my work as a photographer. Beauty is complicated; it's an individual response to how we live our lives -- but it can also encompass kindness and compassion.

I don't think that real beauty is easily defined, otherwise it's cliched. I'm a self-identified butch dyke, I'm a big woman, and even though I might struggle with my body, I still find it really beautiful in terms of what it can do. Artists who challenge the idea that only a certain type of person or body can be valued are showing that what's considered "the other" can be beautiful too.

I find an enormous amount of beauty in being political and intellectual. Beauty isn't necessarily surface-level; it can also be about one's personal life and contain conflicting ideologies. You can create a certain aesthetic around those ideas, draw someone in with an element of beauty, and then push those boundaries by posing questions.

"Self-Portrait/Nursing" (2004) Credit: Catherine Opie

It's also important to make photographs that inspire one to really look, to be drawn in, instead of just glancing at something quickly. For me, beauty is also about being held.

I've experienced that captivating feeling in a series of three portraits taken by Dutch photographer Rineke Dijkstra in 1994. They feature three different women in the hospital, just after giving birth. They stand, nude, holding their newborns, and at times you see a trail of blood running down a leg, or the marking of a caesarean scar. I find beauty in the honesty of these images, and I'm moved by how they show a mother's protective nature.

People in my community were shocked when I became pregnant. It didn't seem like butch women like me birthed children.

But, I knew I always wanted to be a mom. When I gave birth to Oliver in 2002 , I took a self-portrait while nursing, recalling the forms of Madonna and child.

"Self-Portrait/Cutting" (1993) Credit: Catherine Opie

"Self-Portrait/Nursing" became the third in what could be considered a trilogy of photographs, with my earlier photographs "Self-Portrait/Cutting" and "Self-Portrait/Pervert" from the 1990s. The photograph with "pervert" cut into my chest, when I participated in Los Angeles's queer BDSM community, is a little too extreme for me now. It was important for me to make it, but there's some work that you don't necessarily want to live with every single day. I was talking about beauty in it, though, and the formality of a photograph. It engages you; it's very well-designed. For a large queer body to both hold space, and to seduce you, was a radical concept.

For me, it was perfect to complete this trilogy with the nursing image, which fulfilled my own longing to be a mother. I love the photograph because he was such a beautiful baby -- and he still is. At my last opening, Oliver sat on my lap and told me how proud he was of me as an artist. The fact that my 18-year-old son will still come and cuddle in my lap, mirroring the moment I photographed him while nursing, is incredibly touching to me.

"Rusty" (2008) Credit: Catherine Opie

I try to show that kind of vulnerability when photographing male beauty. In the 2000s, I took tender photographs of high school football players that show both their vulnerability as well as their performance of masculinity. Some of those images are hung now for the "Masculinities" show at the Barbican in London.

Chicken from "Being and Having" (1991) Credit: Catherine Opie

The show also includes images from "Being and Having," which I hung in 1991, of my queer friends and I acting out exaggerated masculinity in moustaches and beards. The show included portraits of my longtime friend Pig Pen. Pig Pen is beautiful to me -- it's in their butchness, the way they hold their body. I'm drawn to the slippage of identity. We met in Los Angeles, running in the same circles, hanging out in queer clubs and being a part of grassroots organizations like Act Up and Queer Nation. The presence of our friendship, which spans decades and multiple bodies of work, is also really important to me. Sentimentality and nostalgia can also shape our perceptions of beauty.

"Pig Pen (Tattoos)" (2009) Credit: Catherine Opie

Today I think we're getting around to understanding that it's also important to show people who are aging. There's something beautiful to that. I think about portraits of John Baldessari, David Hockney or Edith Windsor, all taken in their 80s, and what it means to kind of sit with somebody and photograph them when they're of that age. It's another way of talking about the beauty of longevity. Youth culture isn't the only important area to explore in beauty and fashion. It's important to represent the transitions of a person's body throughout their life.

"David" (2017) Credit: Catherine Opie

We have to question the norm. And if we question the norm, then we question ideas that surround beauty. For me, beauty has to encompass more about the human condition and the times we are living in. I see just an enormous amount of hatred these days. It's troubling; I didn't think that we would return to this level of bigotry. In response, we have to figure out how to really support one another -- to treat people with decency. It's important to realize that beauty is actually tied to ideas around happiness. How do we become fulfilled in that way? And can we fulfill it through acts of kindness?

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Catherine Opie: 'Beauty has to encompass more about the human condition' - CNN

Making The Jetsons Jealous: Peter Diamandis Says The Future Is Better, And Coming Faster Than You Ever Dreamt – Thrive Global

Flying cars. Peopleliving forever. The cost of education, energy, and food brought close to zero.

It would soundlike crazy talk if it were coming from anyone other than Peter Diamandis, creatorof the XPRIZE, founder of the Abundance 360 conference, and author of the mostinfluential books ever written about what the future holds.

In Abundance, published in 2012 and co-authored with Steven Kotler, Diamandis described how technology is bringing the bottom billion out of poverty and into a healthier, happier, opportunity-filled world. They then carried the theme forward in their second book, Bold, and returns to the ideas in their latest effort, The Future Is Faster Than You Think: How Converging Technologies are Transforming Business, Industries, and Our Lives, again with co-author Steven Kotler.

The opportunities that are coming our way in the next five to ten years are astonishing, Diamandis says. Entrepreneurs need to realize that we will make more wealth in the next decade than in the entire previous century. The worlds biggest problems are also the worlds biggest business opportunities. Technology is going to transform absolutely everything, and much faster than people realize.

Diamandis says thathis purpose in writing The Future IsFaster Than You Think is to remove fear.

The mission of the book, he says, is to give people a hopeful but also opportunistic view of the future. Im trying to show where the technologies are and how things will change in every area of life.

Diamandis ticks offtransportation, healthcare, energy, food, insurance, finance, entertainment, andretail as among the areas that will be radically different before we know it.He speaks of the convergence of multiple forms of technology coming together tocreate new business models.

Very few people, he says, when they were children, dreamt of working a cash register, being a parking attendant, or being a housekeeper. They probably had more aspirational objectives for their lives.

The three Ds that will dominate the next decade are dematerializing, democratizing, and demonetizing. In other words, so many functions are moving to the digital world, where they become open to everyone, and not just a select few. At the same time, the cost of living is going to drop so radically that people wont have to work for the sake of paying for their lives. More and more people will be able to do whatever they really want to do.

The book explains wheretechnology is headed, and then demonstrates how the convergence of these newtechnologies will enable opportunities for people that sound like something outa science-fiction movie. It concludeswith a section on the risks and migrations attendant to those changes.

Take longevity, Diamandis says, warming to one of his favorite topics. We are approaching whats called longevity escape velocity. This means that for every year you grow older, science finds a way to extend your life by one year. Age becomes a treatable disease instead of a death sentence.

Diamandis takespains to explain that the societal shifts, due to the obviation of jobs likelong haul trucker, will not be as abrupt or disastrous as people think. In thebook, he notes that it will take half a century before all of todays jobs vanish,only to be replaced by even better opportunities for people at every level ofthe socioeconomic spectrum.

Is he worriedabout a caste system evolving, creating a world of a few technological havesand countless technological have-nots?

Not at all, Diamandis replies. If you look back anywhere from a few centuries to a few millennia, kings, queens, and pharaohs were the haves and everyone else lived in absolute squalor. For millennia, 99.9999% of human beings have lived in survival mode.

Going forward, there will certainly be a small number of super-haves, as there have always been, but everyone else will have unlimited access to healthy food, water, energy, and healthcare, at low or no cost. Thats something unprecedented in human history.

In tomorrows world, every child will be born to extraordinary opportunity. Thats a lot better than the world we know today.

Diamandis pointsout that the technology tends to get radically cheaper as more people adopt it,which means that new opportunities become available to the masses at much lowerprice points than those paid by early adopters.

The only people who had the first cellphones were Wall Street investment bankers, he says. Those phones were the size of briefcases, they cost a million dollars, and they dropped calls every two blocks. But as time went on, the cost of a phone dropped to the point where practically everyone on the planet can have a smartphone. Thats why I say, democratized equals demonetized. The future is coming faster, and better, and cheaper than anyone can imagine.

And these thingsarent 25 to 50 years from now. Theyre literally around the corner. The bookexplains how and why.

For furtherinformation, and special pre-publication bonuses, including copies of Abundance and Bold for people who buy the book in advance, visit http://www.futurefasterbook.com.

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Making The Jetsons Jealous: Peter Diamandis Says The Future Is Better, And Coming Faster Than You Ever Dreamt - Thrive Global

Why Is Everyone Running for President So Old? – The National Interest Online

Every remaining major candidate vying to become anominee for the U.S. presidency is aseptuagenarian. While the aged field of candidates comes with its own set of concerns, it is asign of the countrys progress toward keeping people alive and healthy for longer than ever before.

In the race for the highest office in the land, the socalled Silent Generation is making itself heard. Senator Bernie Sanders (DVT), the oldest candidate, is 78years old, as is former New York mayor Mike Bloomberg, who dropped out of the race this morning. Former vice president Joe Biden is 77years old. President Donald Trump is 73years old. At 70years old, Senator Elizabeth Warren (DMA) is the youngest of the major candidates. She was born in mid1949.

Several major candidates have birthdays coming up before the Election Day. By November 3rd, Senator Sanders will be 79, President Trump will be 74 and Senator Warren will be 71years old. Biden will turn 78 shortly after the election, on November 20th.

When the current President was sworn into office at the age of 70, he was the oldest president ever inaugurated in the United States. It looks like he or whoever assumes the presidency in 2021 will beat that record.

Even among the minor candidates still in the race, septuagenarians are represented. Former Massachusetts Governor Bill Weld, who is challenging the president for the Republican nomination in aprotest campaign, is 74years old. Congresswoman Tulsi Gabbard (DHI), who ispolling atless than 2percent nationally, is the only remaining candidate born after 1950. She is 38.

When the septuagenarian candidates were born, the polio vaccine was yet to be created, there were no commercial computers, no human being had yet been to outer space and interracial marriage was still illegal in several U.S. states.

In 1950, U.S. life expectancy stood at 68.2years,accordingto the U.S. Center for Disease Control and Prevention (CDC). The U.S. life expectancy has soared since then and atemporary dip over the last couple of years due to the opioid epidemic has since reversed. The CDCs most recent figures estimate that the U.S. life expectancy reached78.7yearsin 2018an increase of 0.1year from 2017. That means that just within the lifetime of Senator Warren, the youngest major candidate, U.S. life expectancy has expanded by over adecade.

Healthy life expectancy or the number of years one can expect to enjoy good health, has also increased significantly. An American can expect to enjoy around 68 and ahalf years of good health, on average, according to the World Health Organizationsmost recentestimate, for 2016.

The actuarial tables suggest that whichever septuagenarian wins in November, he or she willlikelysurvive the next four years. Based on the average for their age, thats a76.8 percent chance for Sanders; 79.2 percent for Biden; 84.8 percent for Trump and, reflecting that women tend to outlive men, a91.8 percent chance for the relatively youthful Warren. Still, there is no doubt that the vice presidential candidates willmattermore than usual this election cycle.

The countrys Founding Fathers likely could not have imagined afuture with such remarkable longevity. The septuagenarian field of major candidates has sparked concerns over the state of the various candidates health and mental acuity. While those worries should be taken seriously, the fact that so many septuagenarians are running reflects the broader demographic trend of Americans livinglonger, healthier lives and remaining active for many more yearsa fact that should be celebrated.

This article by Chelsea Follett originally appeared in the CATO at Liberty blog in 2020.

Image: Reuters.

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Why Is Everyone Running for President So Old? - The National Interest Online

Dermal Fillers Market is Projected to Expand at a CAGR of 8.6% from 2018 to 2026 – 3rd Watch News

Transparency Market Research (TMR) has Published a new report titled, Dermal Fillers Market Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 20182026. According to the report, the global dermal fillers market was valued at US$ 2,584.9 Mn in 2017. It is projected to expand at a CAGR of 8.6% from 2018 to 2026. Expansion of the market can be attributed to technological advances leading to the development of newer hyaluronic acid dermal fillers with higher efficiency and long-lasting abilities, marketing strategies employed by market players, increasing awareness about these products on social media, and rising fad of anti-aging among people.

Biodegradables is anticipated to be a lucrative segment

The report offers detailed segmentation of the global dermal fillers market. Based on product, the market has been classified into biodegradable and non-biodegradable. The biodegradable segment dominated the market in 2017. It is likely to maintain its dominance during the forecast period. Biodegradable dermal fillers usually consist of purified dermal components derived from animal, human, or bacterial sources. Expansion of the segment can be attributed to the high safety profile of these fillers and recent technological advances that offer longevity on the usage of biodegradable fillers.

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Hyaluronic acid segment to expand at a robust CAGR

In terms of material, the dermal fillers market has been split into calcium hydroxylapatite, hyaluronic acid, collagen, poly-l-lactic acid, PMMA, fat, and others. The hyaluronic acid segment dominated the market in 2017. It is likely to maintain its dominance and expand at a high CAGR during the forecast period. More than 60% of dermal filler procedures performed globally are carried out with hyaluronic acid fillers. According to International Society of Plastic Surgeons (ISAPS), over 3,298,266 hyaluronic acid dermal filler procedures were performed annually. Additionally, technological advances have led to the development of various forms of hyaluronic acid dermal fillers, which differ according to the concentration of hyaluronic acid and the degree of crosslinking. These are known to enhance the longevity of the filler effect. These factors are anticipated to drive the market.

Rising fad of anti-aging driving the facial line correction treatment segment

Based on application, the dermal fillers market has been segregated into facial line correction treatment, lip enhancement, scar treatment, and others. The facial line correction treatment segment dominated the market in 2017. It is likely to continue the trend and expand at a high CAGR during the forecast period. Expansion of the segment can be attributed to the rising trend of anti-aging and increasing awareness about esthetic appearance among people. Additionally, facial line correction treatment appeals to varied age demographic, ranging from young adults to enhance their youthful features to middle-aged adults for volume restoration and older individuals to maintain age-related symptoms. Marketing strategies employed by market players, wherein celebrities promote their products, are fueling the desire among the population to mimic their favorite celebrities. This, in turn, is boosting the demand for facial line correction treatment procedures.

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Dermatology clinics to expand at high CAGR

In terms of end-user, the market has been split into hospitals, ambulatory surgical centers, dermatology clinics, and others. In terms of revenue, the hospitals segment dominated the market in 2017. It is likely to maintain the trend during the forecast period. However, the dermatology clinics segment is anticipated to expand at a robust growth rate during the forecast period. Robust expansion of the segment can be attributed to the increase in dermatology consultations and surge in preference for specialist dermatologists.

Growth in Asia Pacific to be driven by Japan and India

In terms of revenue, North America dominated the global dermal fillers market in 2017. The U.S. was the major revenue generating country in the region. Expansion of the market in the country can be attributed to a rise in the number of dermal filler procedures performed annually. According to American Society of Plastic Surgeons (ASPS) over 2.3 million dermal filler procedures were performed in 2017, an increase of over 3% over 2016. The market in Asia Pacific is expected to expand at a high CAGR during the forecast period. Expansion of the market in the region can be attributed to the increasing demand for dermal filler procedures in Japan, India, and China. Hyaluronic acid dermal filler procedures are highly common non-surgical procedures performed in various countries across Asia Pacific, including Japan, China, India, and Thailand.

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Strategic acquisitions is a key strategy adopted by key players

The report provides profiles of leading players operating in the global dermal fillers market. These players include Allergan plc, Sinclair Pharma (a subsidiary of Huadong Medicine Ltd), Merz Pharma GmbH & Co. KGaA, Nestle Skin Health (Galderma), BioPlus Co., Ltd., Bioxis pharmaceuticals, SCULPT Luxury Dermal Fillers LTD, Dr. Korman Laboratories Ltd., Prollenium Medical Technologies, Advanced Aesthetic Technologies, Inc., and TEOXANE Laboratories.

For instance, in 2014, Nestle acquired several dermatology brands owned by Canada-based pharmaceuticals group Valeant, which added a range of dermal fillers to the Nestle skincare business. Nestles skincare business was established through the acquisition of Galderma. In the same year, Allergan acquired Aline hyaluronic acid (HA) thread technology from Aline Aesthetics, a wholly owned subsidiary of TauTona Group.

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Our data repository is continuously updated and revised by a team of research experts so that it always reflects latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports.

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Dermal Fillers Market is Projected to Expand at a CAGR of 8.6% from 2018 to 2026 - 3rd Watch News

Zelda Was One of the Greatest Modern Writers of Religious Experience in Any Language – Mosaic

In the world of modern Hebrew letters, some names have achieved international recognition: from S.Y. Agnon and ayyim Naman Bialik to, more recently, Amos Oz and Yehuda Amichai. The names of others, whose contributions to Hebrew literature may be no less significant, tend to resonate in smaller, more localized circles.

Among the latter figures is the poet Zelda Shneerson Mishkovsky (1914-1984)known simply as Zelda to her many devoted readers in Israel. Indeed, her place in the world of Hebrew letters is secure, having been recognized through the award of both the Bialik and the Brenner prizes,two ofIsraels highest literary honors. That place is also unique: more than three decades after her death, Zelda remains one of the greatest modern writers of religious experiencein Hebrew or in any other language.

Who was she?

Zeldas rendering of religious experience was undoubtedly informed by her early life. Born in Russia in the waning days of the tsarist empire, she spent her first decade under the new dispensation of the Bolsheviks. Her formative childhood environment, however, was the world not of Communist atheism but of Chabad asidism. Zeldas first cousin, older than she by a dozen years, was Menachem MendelSchneerson, who in 1950 would become the seventh leader of the Chabad-Lubavitch dynasty: the Lubavitcher rebbe.

At twelve, Zelda emigrated to mandatory Palestine with her family. The Schneersons settled in Jerusalem (bejeweled in the sun,/ smiling like a bride), where she would spend most of her adult life. Nor did the spiritual world of her early years ever leave her. She remained devoutly religious her whole life and would often allude to asidic themes and symbols in her poetry. That poetry depicts a world of divine sparks and miracles, a world in which God is at times a living entity, as solid as a human lover or friend. But hers is also a world of profound loneliness and isolation, a world in which death maintains an unshakable presence and God is often hidden.

Zeldas father died about a year after the familys move to Jerusalem, and her grandfather soon after. In Jerusalem, she attended a religious girls school and then the Mizrai Teachers Seminary. It was while a student at the latter that she first began writing and publishing poetry in newspapers and magazines.

Over the next two decades, Zelda lived in Tel Aviv, Jerusalem, and Haifa, teaching Hebrew to new immigrants, caring for her ailing mother, and working as a teacher in an elementary school. Even as a teacher, she brought her radiant vision to her work, calling small kindnesseslike lending an eraser, or handing out drawing papermaking sparks. Among her second-grade pupils was Amos Oz, who many years later, in his 2002 memoir A Tale of Love and Darkness, would write:

[Zelda] revealed a Hebrew language to me that I had never encountered before. . . . A strange anarchic Hebrew, a Hebrew belonging to stories of the pious and to asidic tales and folk parables, a Hebrew overflowing with Yiddish, violating every rule, mixing feminine with masculine, present with past, noun with adjectivea sloppy, even muddled Hebrew.

But what vitality there was in these stories! When a story was about snow, it seemed written in words of snow. And when it was about fires, the words themselves burned.

Despite her pedagogical gifts, Zelda felt teaching stifled her poetry. When she married ayim Aryeh Mishkovsky in 1950, she gave up teaching and began writing more intensely. Still, it wasnt until 1967after much urging from her husband and friendsthat Leisure, her first book of poems, was released. She was fifty-three years old.

Leisurelaunched Zelda from near-anonymity into the heart of the Israeli literary world. Some of the excitement was undoubtedly due to the novelty of her biography, buther work also gained attention for breaking poetic ground. Ignoring the genre boundaries and rhythmic patterns that then still largely governed the writing of Hebrew verse, her work, as the singerChavaAlbersteinwould observe, sounded a new melody on the Hebrew poetry scene.

From 1967 onward Zelda published prolifically, releasing a book of poetry every three to four years. Her second book, The Invisible Carmel (1971), was dedicated to the memory of ayim, who passed away shortly before its publication. In the following years, deathalways a major themebecame even more prominent. Her preoccupation with mortality led to one of her most brilliant poems, Heavy Silence, a meditation on language, meaning, and grief.

Here and throughout, the translations are by Marcia Falk in The Spectacular Difference: Selected Poems of Zelda (2004):

Death will take the spectacular differencebetween fire and waterand cast it to the abyss.

Heavy silencewill crouch like a bullon the names we have giventhe birds of the skyand the beasts of the field,the evening skies,the vast distances in space,and things hidden from the eye.

Heavy silence will crouch like a bullon all the words.And it will be as hard for me to partfrom the names of thingsas from the things themselves.

O Knower of Mysteries,help me understandwhat to ask foron the final day.

Few would have expected Zeldas poems, which, like this one, brim with allusions to biblical and mystical texts, to resonate with readers across all segments of Israeli society. Yet she was never exclusively either a poets poet or a aredipoet. Indeed, each of her sixbooks was a national bestseller, and the ranks of her admirers included kibbutzniks, soldiers, yeshiva students, and academics.Her verses have been put to music in popular Hebrew songs, most notably byAlberstein, and one poem in particular, Each of Us Has a Name, is a frequent feature of Holocaust Remembrance Day ceremonies in Israel.

It is true, however, that today, despite her popularity, she is more likely to be mentioned by the keepers of advanced Israeli culture as a token curiosity (Israels first religious female poet) than as a serious literary artist. Nor was she ever recognized with the Israel Prize, the nations highest cultural honor. In 2004, the literary critic Alit Karper wrote in Haaretz that Twenty years after her death from cancer, Zelda is mainly a very forgotten poet. And outside of Israel, as I noted at the outset, her work is virtually unknown.

Countless forces contribute to the making of a writers reputation and cultural longevity, some of which have little to do with the actual work. (The Canadian scholar H.J. Jackson once listed such fame-enhancing factors as dying young, having a politically contentious youth, and living in a pretty, pilgrimage-friendly place.) As for Zelda, one might speculate that her work has been overlooked in part because her poems seem so simple.

In contrast to poets whose work cries Decipher me!, Zeldas poemsparticularly those rooted in concrete imagesexhibit a straightforwardness that makes them approachable despite their often antiquated language, minimal punctuation, and erratic line breaks. Thus, a poem titled The Crippled Beggar 1 is about a crippled beggar; another, called Strange Plant, is about a strange plant. Nor is this an artifice: according to her translator Marcia Falk, Zeldas poems are never put-ons, never show-offs, and above all, never artificial. . . . They seem, rather, to have been born whole and delivered to us in a single breath.

This accessibility is one of Zeldas greatest strengths, for her poems can be read and appreciated by readers of various skills and levels of Jewish literacy. But the fact that her poems do not declare themselves as difficult has undoubtedly led some who should know better to dismiss her work after skimming only the surface. Take, for example, the following untitled poem:

In the morning, I thoughtLifes magic will never return,it wont return.Suddenly in my house, the sunis a living thing,and the table with its breadgold.And the flower and the cupsgold.And the sadness?Even thereradiance.

Simple enough. The poem contains no obvious allusions or impressive formal displays, and its main technical achievement seems to lie in its use of abrupt line breaks that, in emphasizing the moments transience, curtail any hint of sentimentality.

But, as always with Zelda, there is more here than meets the eye. In her system of personal symbols (other instances include The Sun Lit a Wet Branch, The Old House, Strange Plant, and many more), gold is associated with light and divine presence: a connection most likely adapted from the kabbalistic idea of the infinite light of God overflowing through metaphysical emanations to the lower human world. In this poem, the idea of an impassable gulf between the earthly realm and the realm of the divine is openly challenged. God, Zelda suggests, can be found not only in the synagogue but in the small nouns that make up our world: the table with its bread, a bunch of flowers, cups.

But there is more. The quiet lines and the table with its bread/ gold./ And the flower . . . / gold are borrowed, nearly word for word, from Kings 1 7:48-49, a passage describing the golden table and vessels in the Great Hall of Solomons Temple. The terms, almost seamlessly incorporated into the body of her text, carry theological weight, implying not only that God is present in the mundane but that discerning the divine in the mundane is in itself an act of worship.

Embedded within this unassuming poem is thus a distinctively asidic theology, an alternative to the desacralized cosmos in which most of us live. That theology is communicated through reference to Judaisms sacred texts, deployed so deftly as to be nearly invisible. Zeldas work can be read and enjoyed without knowledge of her specifically asidic background, but it cannot be fully appreciated without a sense of her religious world.

In this same connection, its important to stress that some of the best notes struck by this poet of religious experience reflect the moments when that experience fails to line up precisely with theology. Take, for example, Who Can Resist the Beauty of the Light:

I bore my anger to show to the light,seeking comfort in its beauty,

but I was not worthy in its eyes,I was not worthy in its eyes.

Why is your life dark? it said.You are not in the depths of the pit.This must be a lack of love.

And I wept.I wept deeply.

Like many of Zeldas poems, this one has a patina of childishness. The poem is filled with simple contrasts: light/dark, comfort/disquiet, life/(intimated) death. As in a childrens story, the light speaks. As in a nursery rhyme, the poem doubles and repeats. But the simplistic structure and fable-like images belie the complexity of the literary and emotional framework.

Most obvious in this respect is the reference to Psalms 88:7: Thou hast laid me in the nethermost pit, in dark places, in the deeps. This psalm is itself one of the darkest in that biblical book, its mood described by the religious historian Martin Marty as a wintry landscape of unrelieved bleakness. Unlike other psalms dealing with themes of death and abandonment, Psalm 88 is essentially nineteen verses of unmediated gloomwhich makes it a fitting background to the emotional state of Zeldas speaker.

Other allusions in the poem are similarly apparent only in the original Hebrew, and then mostly to readers deeply familiar with Judaisms foundational texts. Since this presents a common problem in reading Zeldas work in translation, we may pause here for a word about Marcia Falks efforts to overcome it. Although her renderings excel at conveying the intimacy and simplicity of Zeldas work, more subtle references are sometimes elided. Here, for instance, the word translated by Falk as my anger () might better be rendered as my disquiet. The phrase appears in Exodus, Proverbs, and Job, among other places, but its root form appears most notably in Samuel 2 19:1together, significantly, with a form of Zeldas archaic (and I wept), another highly inflected word in the poem.

This is the only verse in the Bible in which both words appear in conjunction, and at a moment of extreme intensity: And the king was much moved, and went up to the chamber over the gate, and wept. The verse marks the start of Davids lament for Absalom, perhaps the most famous of all biblical expressions of grief: O my son Absalom, my son, my son Absalom! would I had died for thee, O Absalom, my son, my son!

Yet the context of the kings outcryin particular, the fact that Absalom was killed as he attempted a coupis sometimes overlooked. In fact, the lament is itself followed by a considerably less famous passage in which David is reminded by his nephew Joab, who is also the commander of the royal army, that had Absalom lived and the coup succeeded, the kings wives, sons, daughters, and servants would all have been slaughtered.

In other words, Absalom, O Absalom! is an expression of inappropriate grief. And it is precisely in that sense that Zeldas references to Samuel align her I with David. Like David, Zeldas speaker senses that her griefor at least the depth of itis misplaced, uncalled-for. She mourns, like David, but believes she ought not to. Her life is dark, but she, like him, is not truly in the nethermost pit.

Also critical to understanding Who Can Resist the Beauty of the Light is some knowledge of the Chabad approach to grief and joy, and in particular Chabads emphasis on divine providence: the belief that, for the faithful, all that occurs is ultimately the result of Gods benevolent care for us. Complete trust in that benevolence allows an individual to welcome suffering with joy and love, for everything has its origin and its end in God, the Infinite Light invoked in the poems title.

For Zelda, these ideas were not abstract theological concerns. The death of her husband ayim left her bereft. Even years later, many of her poems describe the pain of widowhood. As letters exchanged between her and her cousin Menachem Mendel Schneerson reveal, the opposing spiritual valences of suffering and grateful happiness were at the forefront of her mind. At one point, Schneerson writes, From the spirit of your letters, I get the impression that though I keep writing you to take a more joyful perspective, . . . my words have made no mark. . . . But I will persist, and repeat myself even 100 times, and you will forgive me.

Despite these urgings, Zelda was unable to subsume her pain in faith. Her poems suggest that she saw this lack of love as a spiritual failing. And that brings us to the core of Who Can Resist the Beauty of the Light, which lies precisely in the speakers sense that she has failed to live up to ideals she feels are impossible but cannot relinquish. Caught between what she believes (all that occurs is the result of Gods will) and what she experiences (darkness and pain), the speakers only recourse is tears: And I wept./ I wept deeply.

In less skilled hands, that thought, along with the poem that expresses it, would have tipped into sentimentality, or blasphemy. But Zelda navigates the tension with grace. By suffusing her lines with words from sacred Jewish texts and Hebrew liturgy, she creates a work that, even in its angst, reads also as an expression of stubborn, stiff-necked love. If Who Can Resist the Beauty of the Light does not end with a reevaluation of the speakers disquiet, neither does it conclude with a rejection of the light. Instead, pain stands alongside belief, neither one dislodging the other, neither one offering resolution.

Religious experience is notoriously difficult to express in words. The reason may owe in part, as Wittgenstein suggested, to the difference between how we use and relate to religious language and how we use and relate to everyday speech. In part it may also owe to the fact that the most meaningful religious experiences are often characterized by paradox: think of the medieval Christian mystic Julian of Norwichs vision of a small hazelnut that somehow also contains everything that is made.

Of all the possible modes of linguistic transmission, perhaps the one uniquely suited to the expression of religious experience is poetryprecisely because of poetrys capacity to convey paradox, holding multiple contradictory ideas open at the same time. Its therefore unsurprising that almost all of the Hebrew Bibles most moving expressions of religious experience derive from the poetic books: Ecclesiastes, Psalms, Job, Song of Songs, Proverbs, Lamentations. These are not the texts that give us answers, but the ones that best present our questions while assuring us that we are not alone in asking them.

Like those biblical books, Zeldas poetry speaks to the tension of a lived religious life, the places where theology and experience refuse to meld. In her work, the divine is at once radically immanent and hopelessly distant. Death negates human instrumentality, but also allows for the discernment of wonder. A righteous God permits the faithful to suffer.

Theodicy, suffering, redemptionits all there. And that is what entitles Zeldas work to a place at the center of the modern Hebrew canon and to be recognized for what it is: a masterful expression of religious experience that, refusing both blasphemy and sentimentality, offers instead a form of prayer.

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Zelda Was One of the Greatest Modern Writers of Religious Experience in Any Language - Mosaic

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