Kaguya Selene probe crashes into the Moon
Japan Aerospace Exploration Agency - en.wikipedia.org Posted at http://www.simotron.wordpress.comFrom:tsunchooViews:0 0ratingsTime:01:01More inScience Technology
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Introduction To Computational Fluid Dynamics – Video
Introduction To Computational Fluid Dynamics
ll4.me Introduction To Computational Fluid Dynamics Introduction to Computational Fluid Dynamics is a text for mechanical, aerospace and chemical engineering students. EAN/ISBN : 9780511128349 Publisher(s): Cambridge University Press Format: ePub/PDF Author(s): Date, Anil W. Introduction to Computational Fluid Dynamics is a text for mechanical, aerospace and chemical engineering students. EAN/ISBN : 9780511128349 Publisher(s): Cambridge University Press Format: ePub/PDFrom:dorothytucker9865Views:0 0ratingsTime:00:13More inPeople Blogs
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USAF #12 – Video
USAF #12
WOOHOOOO! BOOKED! Aerospace Medical Service /med tech/lpn/nurse 4n031From:StephthemonstaViews:0 0ratingsTime:01:16More inEntertainment
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Raise Award – Video
Raise Award
October 18, 2012:US Secretary of Transportation Ray LaHood personally congratulated Miraj Rahematpura `12, Christopher Muckle `12, and Mario Chris `13 as the first recipients of the Secretary #39;s RAISE Award (Recognizing Aviation and Aerospace Innovation in Science and Engineering).From:XHSCTWebmasterViews:0 0ratingsTime:03:56More inEducation
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Alumni Profile: Joseph Anderson, USAF Surgeon – Video
Alumni Profile: Joseph Anderson, USAF Surgeon
Pre-Medical Society #39;s Outstanding Service Award in Medicine Award -- Joseph Anderson currently serves as the Air Force Reserve #39;s Command Surgeon stationed at Robins AFB. He oversees the medical care provided by 6000 medical personnel to more than 60000 Reservists. The Air Force Reserve provides over 60 percent of the aeromedical evacuation capability of the Department of Defense. Formerly, Anderson was assigned to the Secretary of Defense at the Pentagon to develop new pre-deployment training for medical embedded teams. He has extensive experience in health systems development in international peacetime and combat areas having served in Afghanistan and as commander of the 30th Medical Group at Vandenberg Air Force Base in California. Anderson majored in biochemistry at the College of Charleston and was a member of the swim team and Alpha Phi Omega. He received his medical degree from the Uniformed Services University of the Health Sciences and a master #39;s degree in public health from Harvard. Anderson is board-certified in family medicine and aerospace medicine. The Anderson family has strong College of Charleston roots. Joe #39;s parents are Jim Anderson #39;55 and Carolyn Nesbitt Anderson #39;70. His brother, Philip Anderson, graduated in 1981 and Joe met his wife, Regina, while both were students at the College. They now have a daughter, Kathleen, who is a College of Charleston student. Hopefully, their son, Ben, will also choose the College in a few years.From:CollegeofCharlestonViews:1 0ratingsTime:01:33More inScience Technology
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Emerson CQC-13 Update – Video
Emerson CQC-13 Update
Yin to the Yang, broken tip, and new edge..... http://www.emersonknives.com Emerson CQC-13BT Bowie Folding Knife (3.85" Black Plain) This is the first Bowie style folder from Ernest Emerson and it is a beauty. This knife fits like a glove and feels like it was made for you. If you like Bowies and you need a Tactical Folder, then there is no other choice. The ECBF has enough blade and handle for any task. This knife looks good and feels even better. Old world tradition meets the 21st century in this combat proven blade, mounted in an extremely safe and secure handle design of Aerospace Titanium and G-10. It features the patented "Wave opening feature". The CQC-13 series features Emerson #39;s Patented "Wave opening feature" or Remote Pocket Opener. In an emergency or injury situation the knife can be opened with one hand as it is drawn from the pocket. Specifications: Overall Length: 9.0" Blade Length: 3.85" Blade Thickness: .125" Handles: Black G-10 epoxy / glass laminate Lock: Aerospace grade Titanium Blade: 154 CM, 57-59 RC Finish: Black Grind: Conventional V Grind Weight 5.0 oz.From:xiuxiu1313Views:74 8ratingsTime:08:29More inEntertainment
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RHM Peregrine Falcon Bathing #2 (Boeing Aerospace 10/23/12) – Video
RHM Peregrine Falcon Bathing #2 (Boeing Aerospace 10/23/12)
Peregrine Falcon bathing at Boeing Aerospace facility near Kent, Washington.From:sheepruglyViews:2 0ratingsTime:02:49More inPets Animals
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RHM Peregrine Falcon Bathing #2 (Boeing Aerospace 10/23/12) - Video
Al Schwimmer – Wiki Article – Video
Al Schwimmer - Wiki Article
Adolph "Al" Schwimmer (Hebrew: #1488; #1500; #1513; #1493; #1493; #1497; #1502; #1512; lrm;; lrm; 10 June 1917 -- 10 June 2011) was an American-born Israeli businessman who was the founder and first CEO of Israel Aerospace Industries. Biography Schwimme... Al Schwimmer - Wiki Article - wikiplays.org Original @ http All Information Derived from Wikipedia using Creative Commons License: en.wikipedia.org Author: #1495; #1493; #1489; #1489; #1513; #1497; #1512; #1492; Image URL: en.wikipedia.org ( This work is in the Public Domain. )From:WikiPlaysViews:0 0ratingsTime:03:09More inEducation
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Wayne Hale | Space Flight Informed Consent | New Mexico Legislature | NASA | Spaceport – Video
Wayne Hale | Space Flight Informed Consent | New Mexico Legislature | NASA | Spaceport
N. Wayne Hale Jr. is a former NASA engineer. Previously a flight director and space shuttle program manager, Hale served as NASA #39;s Deputy Associate Administrator for Strategic Partnerships prior to his retirement on July 31, 2010. He is currently a Consultant for Special Aerospace Services. The above speech is a recreation from the ISPCS, International Symposium for Personal and Commercial Spaceflight, conference in Las Cruces, New Mexico. Brought to you by the Greater Las Cruces Chamber of Commerce. Produced by Troy Tudor, Vice President of the Greater Las Cruces Chamber of Commerce. Executive Produced by Chris Lang of The LNG Company. Directed by Orlando Martos. Edited by Carson Poe of New Mexico State CMI Creative Media Institute department.From:thelngcompanyViews:1 0ratingsTime:21:38More inFilm Animation
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Wayne Hale | Space Flight Informed Consent | New Mexico Legislature | NASA | Spaceport - Video
Aerospace sells planes to Russia in $88m deal
Waikato company Pacific Aerospace has signed an agreement with a Russian company to build 37 aircraft in an $88 million groundbreaking deal for New Zealand.
The deal with Moscow-based AeroProject 751, whose directors have likened the qualities of Pacific Aerospace's P750 XSTOL aircraft to the legendary Russian assault rifle, the Kalashnikov, will result in New Zealand-made planes being the first certified light aircraft to operate commercially in Russia's underdeveloped general aviation sector.
Under the agreement, Aeroproject, whose principals are in Hamilton with 12 members of the Russian Government's Interstate Aviation Committee putting the P750 through its certification paces, will take delivery of the 37 planes over the next five years.
Aeroproject spokesman Egor Mityaev said the P750s would find a keen market in the Russian medical, agricultural, mining and skydiving sectors.
The planes would fill a void in Russia's potentially huge general aviation sector as the last of 17,000 Russian-made pre-World War II An2 b-planes disappear from the skies, with just three or four United States-made Cessna Caravans operating non-commercially.
Mityaev said Russia was a vast country with isolated cities and towns, had few good roads, extremes of weather, generally poor infrastructure, and its government was keen to develop a new medical aviation structure.
The P750s, which can carry three stretchers and three medical personnel and are designed to operate on very short and difficult terrain runways in extreme temperatures, would also be sold in Russia for agricultural spraying and insect eradication, firefighting, geophysical surveys for mining and oil and gas exploration, and skydiving.
Aeroproject's chief pilot, Vladimir Zhelezniak, said the P750 was unique.
"It has very good construction, very good technology, is very simple, not a big price and needs minimum service and maintenance - like a Kalashnikov."
Pacific Aerospace has sold 74 P750s since the aircraft's launch in the US market eight years ago.
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Vector Aerospace Helicopter Services' Maintenance Facility Reduces Annual Lighting Costs by 72% Using Intelligent LED …
BOSTON, MA--(Marketwire - Nov 7, 2012) - Digital Lumens today announced that Vector Aerospace, an industry-leading provider of maintenance, repair and overhaul (MRO) services for fixed wing and rotary wing aircraft operators around the globe, has upgraded a 158,000-square-foot helicopter maintenance facility to the Digital Lumens Intelligent LED Lighting System. Replacing 400 Watt Metal Halide lamps, the System is saving 72% of lighting energy costs annually, driven by integrated controls that manage lighting behavior, while delivering the high light levels required in the facility.
Vector Aerospace Helicopter Services ("Vector") in Richmond, BC, Canada has reduced lighting-related energy costs from $80,665 to $22,630, or from 51.1 to 14.3 per square foot annually. In addition to flexibility and efficiency savings, Vector management chose the Digital Lumens system for its ability to concentrate high light levels on critical work surfaces without producing glare, integrated daylight harvesting capabilities that save energy by assessing the amount of ambient light and smoothly increasing or decreasing lumen output to meet target light levels, longer life span, and quiet, buzz-free operation. The maintenance-free LED high bay fixtures also eliminate the re-lamping and re-ballasting costs associated with traditional industrial lighting alternatives.
"Before choosing the Digital Lumens system, we looked at a variety of fluorescent and LED alternatives with add-on sensors, but the quality and flexibility just were not there. It looked like sensors were an afterthought," said John Mellas, Facility Manager for Vector. "The Digital Lumens system -- with fully integrated controls and sensors -- is generations ahead of competitors. The savings are already adding up, and are increased by our ability to fine tune fixture settings to meet our ongoing operational needs."
The Vector management team evaluated a variety of lighting alternatives. They found that fluorescents and many LED fixtures disperse light at too high a level, forcing facilities to over-lamp in order to get enough light to critical work surfaces, and producing unacceptable levels of glare. Vector doesn't have any of these problems with the Digital Lumens system. Instead, Vector can direct lighting to where it is needed and modify output settings through the LightRules lighting management software.
"The aerospace industry has been wrestling with high utility bills and the difficulty of getting quality lighting to critical work surfaces for decades," said Michael Feinstein, Vice President of Sales and Marketing for Digital Lumens. "We've been able to solve these challenges for the Vector facility, while improving illumination levels, maximizing energy savings, and offering a rapid project payback."
With daylight harvesting and occupancy sensors built into every fixture, the Digital Lumens Intelligent Lighting system provides Vector with light precisely where and when needed. The fixtures are wirelessly networked, and collect detailed operational data, which they share with the LightRules management software. LightRules also enables the facilities management team to modify lighting settings wirelessly, eliminating the need to touch light fixtures to change settings and behaviors. Vector is achieving lighting savings of more than 707,735 kWh annually at their facility.
About Vector Aerospace Corporation ("Vector")
Vector is a global independent provider of aviation maintenance, repair and overhaul services. Through facilities in Canada, the United States, the United Kingdom, France, Africa and Australia it provides services to commercial and military customers for various types of gas turbine engines, components and helicopter airframes.
A comprehensive overview of Vector's capabilities can be viewed at http://www.vectoraerospace.com.
About Digital Lumens
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FLYHT Aerospace Solutions Ltd. Investor Presentation Now Available Online
CALGARY, ALBERTA--(Marketwire - Nov 7, 2012) - FLYHT Aerospace Solutions Ltd. (TSX VENTURE:FLY)
Editors Note: There is a photo associated with this release.
On October 24, 2012 The Howard Group hosted its 4th annual "Opportunity Knocks" investor conference in Calgary. Kent Jacobs, Director of Advanced Applications at FLYHT, provided an overview of the company to an audience of investment advisors & private investors.
A recording of the presentation is now available online. Click here to view - http://www.howardgroupinc.com/portals/0/Events.aspx
Highlights on FLYHT are as follows:
About FLYHT Aerospace Solutions Ltd.
FLYHT provides proprietary technological products and services designed to reduce costs and improve efficiencies in the airline industry. The Company has patented and commercialized three products and associated services currently marketed to airlines, manufacturers and maintenance organizations around the world. Its premier technology, AFIRS UpTime, allows airlines to monitor and manage aircraft operations anywhere, anytime, in real time. If an aircraft encounters an emergency, FLYHT''s triggered data streaming mode, FLYHTStream, automatically streams vital data, normally secured in the black box, to designated sites on the ground in real-time. The Company has been publicly traded on the TSX Venture Exchange since 2003 and recently changed its trading symbol from AMA to FLY. Shareholders approved a Company name change from AeroMechanical Services Ltd. to FLYHT Aerospace Solutions Ltd. in May 2012.
AFIRS, UpTime, FLYHT, FLYHTStream and AeroQ are trademarks of FLYHT Aerospace Solutions Ltd.
Caution Regarding Forward-Looking Statements - This news release contains certain forward-looking statements, including statements regarding the business and anticipated financial performance of the Company. These statements are subject to a number of risks and uncertainties. Actual results may differ materially from results contemplated by the forward-looking statements. When relying on forward-looking statements to make decisions, investors and others should carefully consider the foregoing factors and other uncertainties and should not place undue reliance on such forward-looking statements.
To view the photo associated with this release, please visit the following link: http://www.marketwire.com/library/20121106-1107flyht_800.jpg.
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FLYHT Aerospace Solutions Ltd. Investor Presentation Now Available Online
B/E Aerospace to Present at Goldman Sachs Industrials Conference in Boston on November 13, 2012
WELLINGTON, Fla.--(BUSINESS WIRE)--
B/E Aerospace, Inc. (BEAV) will make a presentation to institutional investors at the Goldman Sachs Industrials Conference in Boston, MA on Tuesday, November 13, 2012.
The presentation will begin at 8:00 a.m. Eastern time on Tuesday, November 13, 2012.
A live audio broadcast of the presentation will be available on the investor relations page of the Companys website at http://www.beaerospace.com.
About B/E Aerospace, Inc.
B/E Aerospace is the worlds leading manufacturer of aircraft cabin interior products and the worlds leading distributor of aerospace fasteners and consumables. B/E Aerospace designs, develops and manufactures a broad range of products for both commercial aircraft and business jets. B/E Aerospace manufactured products include aircraft cabin seating, lighting systems, oxygen systems, food and beverage preparation and storage equipment, galley systems, and modular lavatory systems. The Company also provides cabin interior reconfiguration, program management and certification services. B/E Aerospace sells and supports its products through its own global direct sales and product support organization. For more information, visit the B/E Aerospace website at http://www.beaerospace.com.
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B/E Aerospace to Present at Goldman Sachs Industrials Conference in Boston on November 13, 2012
Aerospace group EADS reports flat Q3 profit
European aerospace group EADS which controls Airbus reported flat profits for the third quarter on Thursday but a more than doubling of the net figure for the first nine months of the year.
The group, the European Aeronautic Defence and Space Company, stood by its outlook for growth for the whole of the year.
The net figure for the third quarter was 309 million euros ($394.5 million) from 312 million euros in the same period of last year, representing a fall of 1.0 percent, the group said in a statement.
In the first nine months, however, the net outcome was 903 million euros ($1.15 billion) from 421 million euros for the same period of last year.
In the third quarter, sales rose by 15.0 percent to 12.3 billion euros, and over nine months by 14.0 percent to 37.3 billion euros.
The board stood by its forecast for earnings per share of 1.95 euros and said it expected sales to rise by more than 10.0 percent, having referred to 10.0 percent in its statement at the end of the first six months of the year.
The programmes by Airbus for building airliners were in line with the timetables laid down, the company said.
The first flight of the A350XWB, a long-haul aircraft made mainly of composite materials, was still planned for the middle of 2013 for entry into service at the end of 2014.
The company acknowledged that the programme was highly ambitious.
In the first half of this year, EADS made a provision of 124 million euros in respect of this latest aircraft.
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SpeedNews Launches Global Aerospace Manufacturing Conference
LOS ANGELES, Nov. 8, 2012 /PRNewswire/ --Penton Media's SpeedNews today announced the launch of its "Aerospace Manufacturing Conference" to address a wide range of business and operational topics affecting the timely delivery of products and services across the aerospace industry supply chain, and promote an open dialogue among industry thought-leaders to innovate practical, sustainable solutions.
The new event, the sixth addition to the SpeedNews Conferences portfolio, will be held April 9-10, 2013 at the Charleston Place in Charleston, SC. The event is being produced in partnership with the Charleston Regional Development Alliance (CRDA), and in association with Penton's IndustryWeek, the leading source of business information and insight for manufacturing industry professionals.
"When we launched our 'Aerospace Raw Materials & Manufacturers Conference' in 2011, we also uncovered demand for deeper knowledge of how to better align manufacturing and the supply chain," said Joanna Speed, managing director of SpeedNews Conferences. "Our new Aerospace Manufacturing Conference responds with a dynamic, face-to-face forum focused on helping industry professionals gain critical insights that can improve their operations."
The decision to debut the event in South Carolina recognizes the state's growing influence as an aerospace manufacturing base. More than 180 aerospace engineering companies, including design firms, service providers, and distributors employ more than 20,000 people in the state.
"South Carolina is a great place to do business. It's also a great place to host an international conference related to one of our state's major industries. The aerospace industry is solid in our state, and we want more businesses to locate here," said South Carolina Governor Nikki Haley. "I am excited to participate and welcome aerospace industry experts from around the world to our great state next spring."
Delegates attending the SpeedNews Aerospace Manufacturing Conference will learn about the latest manufacturing products and software technologies to improve productivity and profitability for their operations. The agenda will cover a wide range of topics including design, advanced materials, engineering, technology, equipment, components, tooling and machining. These capabilities are central to the industry, and have played a significant role in fueling South Carolina's aerospace economy.
"Partnering with SpeedNews to help launch the Aerospace Manufacturing Conference is a fantastic way to showcase the Charleston region as a business destination, and its growing aerospace cluster and assets as leaders in the global aerospace industry," said David Ginn, CRDA President & CEO.
About SpeedNews Conferences SpeedNews Conferences is the leader in producing executive events that serve the information and professional networking needs of senior-level aviation and aerospace leaders, decision makers and industry analysts. From aircraft and engine manufacturing to current financial reports, delegates who attend SpeedNews events walk away with current knowledge from experts to help guide their business plans for the coming year. SpeedNews is a Penton Aviation business.
About IndustryWeek IndustryWeek brings together manufacturing business leaders to explore the issues, strategies, trends and technologies that help them build more competitive and profitable companies. IndustryWeek is part of the Penton Manufacturing & Supply Chain Group, whose brands are the trusted resource for relevant news and measurable results. Our team of dedicated editors and thought leaders work together to integrate print, digital and in person events that deliver the return on investment you need. IndustryWeek is a Penton Manufacturing & Supply Chain business.
About Penton Media, Inc. For millions of business owners and decision-makers, Penton makes the difference every day. We engage our professional users by providing actionable ideas and insights, data and workflow tools, community and networking, both in person and virtually, all with deep relevance to their specific industries. Then we activate this engagement by connecting users with tens of thousands of targeted providers of products and services to help drive business growth. Learn more about our company at http://www.penton.com.
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SpeedNews Launches Global Aerospace Manufacturing Conference
LMI Aerospace, Inc. Announces Third Quarter 2012 Results
ST. LOUIS, Nov. 8, 2012 (GLOBE NEWSWIRE) -- LMI Aerospace, Inc. (LMIA), a leading provider of design engineering services and supplier of structural assemblies, kits and components to the aerospace, defense and technology markets, today announced its financial results for the third quarter of 2012.
Third Quarter 2012 Highlights
Third Quarter Results
Net sales for the third quarter of 2012 increased 9.1 percent to $70.6 million, including $2.2 million from the newly acquired TASS, Inc. ("TASS") subsidiary, compared to $64.8 million in the third quarter of 2011. Net income for the third quarter of 2012 was $5.6 million, or $0.48 per diluted share, compared to $4.1 million, or $0.35 per diluted share, in the third quarter of 2011. Third quarter 2012 results include a pre-tax charge of $0.5 million in acquisition costs. Excluding this charge, earnings per diluted share would have been $0.51.
"As the current year has progressed, our expectation has been that sales in the Aerostructures segment would increase sequentially each quarter, and Engineering Services sales would remain at the levels experienced in the first two quarters of 2012," said Ronald S. Saks, Chief Executive Officer of LMI. "We have continued to win new business for both segments, and production rates on certain high volume programs have increased. However, delayed receipt of customer furnished engineering and program delays on certain development projects deferred approximately $7.0 million of sales into 2013. Accordingly, Aerostructures sales guidance for 2012 was reduced by $7.0 million to a mid-point of $175.0 million, and sales guidance for 2013 was increased by the same amount to a mid-point of $216.0 million. In addition, about $5.0 million in expected orders and reduced customer pulls decreased the Aerostructures segment's expected sales.
"In Engineering Services, we increased overall sales expectations by $6.0 million for the expected contribution of our newly acquired TASS subsidiary but decreased our base business forecast by $2.0 million due to uncertainty over two customer programs. We expect our Aerostructures plants to experience considerable growth again in 2013, and gross margins have improved as a result of production efficiencies and improved performance on some complex new programs. In addition, we plan to build some inventory in 2012, especially of those items deferred into 2013 to better manage the growth expected in 2013."
Aerostructures Segment
Increasing production rates and new work on the Boeing 737, 747 and 787 models combined to drive a 4.1 percent increase in net sales of large commercial aircraft products, and the Gulfstream G650 and G280 models contributed to a 10.1 percent rise in corporate and regional market net sales. Reduced sales related to the Blackhawk program were due to decreased demand for certain models at one of the company's customers and increased production at a customer owned assembly facility, which we expect to continue into future periods.
The Aerostructures segment generated gross profit of $12.9 million, or 29.3 percent of net sales, in the third quarter of 2012 versus $11.9 million, or 27.0 percent of net sales, in the third quarter of 2011. Production efficiencies led to this improvement in the segment's margins.
Selling, general and administrative expenses ("SG&A") were $7.5 million in the third quarter of 2012 versus $6.7 million in the third quarter of 2011. Included in these expenses for the third quarter of 2012 is $0.5 million in acquisition expenses.
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Ball Aerospace Celebrates Suomi NPP One Year Anniversary
BOULDER, Colo., Nov. 8, 2012 /PRNewswire/ --The Ball Aerospace & Technologies Corp. Suomi National Polar-orbiting Partnership (NPP) satellite built for NASA, marked one year on orbit, Sunday, Oct. 28, 2012.
(Photo: http://photos.prnewswire.com/prnh/20121108/LA08510)
Suomi NPP is the bridge to the next-generation U.S. civil polar-orbiting Earth-observation satellite system. It provides continuity of critical observations for accurate weather forecasting, reliable severe storm outlooks, global measurements of atmospheric and oceanic conditions such as sea surface temperatures, ozone, and more.
The National Oceanic and Atmospheric Administration uses the satellite data in models for medium- and long-term weather forecasting. Suomi NPP will also improve and extend climate measurements for 30 different environmental data records of the atmosphere, land, ocean, climate, and space environment.
Under contract to NASA's Goddard Space Flight Center, Ball Aerospace built the Suomi NPP satellite, the Ozone Mapping and Profiler Suite instrument aboard the satellite, integrated all five of the spacecraft's instruments, and conducted satellite testing prior to launch. Ball Aerospace is now building the successor to Suomi NPP, the JPSS-1satellite and its OMPS instrument for a 2017 launch. JPSS satellites are being developed by NASA for the National Oceanic and Atmospheric Administration (NOAA).
"The Ball-built Suomi NPP satellite is delivering critical weather forecasting information as well as the data needed for technological and scientific advancement in climate and oceanographic science," said David L. Taylor, president and CEO of Ball Aerospace. "Ball's expertise is now being leveraged for JPSS-1 to ensure these vital global observations continue uninterrupted."
Suomi NPP was launched from Vandenberg Air Force Base into a sun-synchronous orbit, producing coverage of nearly the entire Earth with 14 orbits per day. Suomi NPP orbits Earth every 102 minutes, and to date has completed more than 5,000 orbits capturing data from the Earth's land, oceans and atmosphere.
On Oct. 24, 2012, the NASA/NOAA 2012 ozone measurements were released using the Ball Aerospace-built Ozone and Mapping Profiler Suite (OMPS) aboard Suomi NPP for the first time.
The NPP spacecraft is a member of the Ball Configurable Platform (BCP) family of spacecraft designed for cost-effective, remote sensing applications. Its proven design accommodates a wide range of payloads, including optical applications with sub-meter resolutions and synthetic aperture radar. The NPP spacecraft bus is the eighth of 11 spacecraft built by Ball Aerospace on the same BCP core architecture. In all, this architecture has more than 50 years of successful on-orbit operations.
Ball Aerospace & Technologies Corp. supports critical missions for national agencies such as the Department of Defense, NASA, NOAA and other U.S. government and commercial entities. The company develops and manufactures spacecraft, advanced instruments and sensors, components, data exploitation systems and RF solutions for strategic, tactical and scientific applications. For more information visit http://www.ballaerospace.com.
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Cardiac Cell Therapy Phase III Trial to Treat Refractory Angina
RIO DE JANEIRO--(BUSINESS WIRE)--
CryopraxisTM/CellPraxis aims to start patient recruitment for its Phase III Refractory Angina Cell Therapy Brazilian arm clinical trial by the end of 2012 or early 2013. The phase IIA/B clinical trial study was completed in December 2011. These trials involved the use of a proprietary autologous stem cell formulation (MonocellTM) indicated for neoangiogeneses.
Safety and efficacy of this product was evaluated in patients with refractory angina, a no option disease condition, characterized by severe chest pain for which there is no efficient treatment available, says the President of both Companies, Eduardo Cruz.
ReACT, MonocellTMs derived product, showed evidence of safety and efficacy in our initial clinical trials. All patients included in this trial were classified as Class IV Angina in CCSAC* (the most severe class of chest pain). In the first group of patients, whose data was published**, there was a progressive and sustained improvement in angina symptoms, with 87.5% of the patients completing the clinical trial with a CCSAC score of 0 or 1.
Angina symptom relief began as early as 3 months post procedure with continuing improvement through the 18th month, suggesting that angiogenesis began early, and that it kept evolving 18 months after the procedure. Objective evaluation of stress myocardium perfusion (scintigraphic analysis), after 1 year of follow-up, gave indications of complete myocardial reperfusion in 75% of the patients, says Dr. Nelson Hossne, Medical Director of CellPraxis. Our conclusion was ReACT's specific cell formulation, MonoCell, had a direct correlation to myocardial neoangiogeneses.
About CryopraxisTM (www.cryopraxis.com.br) and CellPraxis (www.cellpraxis.com)
Located at Bio-Rio Biotech Cluster (Rio de Janeiro, Brazil), CryopraxisTM is the pioneer and the largest bank of umbilical cord blood in Brazil and has been in operation since 2001, with approximately 25,000 customers. CellPraxis is a bioengineering company that invests in research projects involving stem cell therapy. Some of these projects are conducted in partnership with institutions like the Federal University of Rio de Janeiro, Federal University of So Paulo, the University of South Florida and Saneron CCEL Therapeutics, Inc. (a USA based biotechnology company dedicated to stem cell research).
Forward-Looking Statement
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements reflect management's current expectations, as of the date of this press release, and involve certain risks and uncertainties. The Company's actual results could differ materially from those anticipated in these forward- looking statements as a result of various factors. The Company's further development is highly dependent on future medical and research developments and market acceptance, which is outside its control.
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Cardiac Cell Therapy Phase III Trial to Treat Refractory Angina
Stem cell therapy using patient’s own cells after heart attack does not enhance cardiac recovery
Public release date: 6-Nov-2012 [ | E-mail | Share ]
Contact: Steve Goodyear sgoodyear@mhif.org 952-807-8365 Minneapolis Heart Institute Foundation
MINNEAPOLIS, MN November 6, 2012 Administering autologous stem cells obtained from bone marrow either 3 or 7 days following a heart attack did not improve heart function six months later, reports a new clinical trial supported by the National Institutes of Health. The results of this trial, called TIME (Transplantation In Myocardial Infarction Evaluation), were presented by Jay Traverse, MD of the Minneapolis Heart Institute Foundation Tuesday, Nov. 6, at the 2012 Scientific Sessions of the American Heart Association in Los Angeles.
The results of this trial mirror a previous, related study (LateTIME) which found that autologous bone marrow stem cell therapy given 2-3 weeks after a heart attack did not improve cardiac recovery. Both TIME and LateTIME were carried out by the Cardiovascular Cell Therapy Research Network (CCTRN), sponsored by the NIH's National Heart, Lung, and Blood Institute.
"The data presented by TIME do much to advance stem cell therapy research," said Jay Traverse, MD of the Minneapolis Heart Institute Foundation and Principal Investigator of this study. "While this study did not provide a demonstrated cardiac benefit after six months, we still learned a great deal. Together, TIME and Late TIME have shown that stem cell therapy is safe, and they have set a baseline in terms of quantity of stem cells, type of stem cells, and severity of heart attack."
TIME enrolled 120 volunteers (avg. age 57) between July 2008 and February 2011; the participants all had moderate to severe impairment in their left ventricle and had undergone coronary stent placement as treatment for the heart attack. The participants were randomly assigned to one of four groups: day 3 stem cell, day 3 placebo (inactive cells), day 7 stem cell, or day 7 placebo. The CCTRN researchers developed a method of processing and purifying the stem cells from the bone marrow of each volunteer to ensure everyone received a uniform dose (150 million stem cells).
Heart improvement was assessed six months after stem cell therapy by measuring the percentage of blood that gets pumped out of the left ventricle during each contraction (left-ventricular ejection fraction, or LVEF). The study found no significant differences between the change in LVEF readings at the six month follow-up in either the Day 3 or Day 7 stem cell groups compared with placebo or with each other; every group showed about a 3 percent improvement in LVEF. However, the researchers found that younger patients randomized to Day 7 had greater improvement in their LVEF compared to their placebo counterparts
"The lack of six-month improvement seen for TIME and, prior to that, LateTIME, does not mean stem cell therapy is not a viable post-heart attack strategy," said Traverse. "Because we have this data we can start to address some parameters; for example this therapy may work better in younger people, or maybe we need to use cells from healthy volunteers (allogeneic) since their cells may provide greater therapeutic benefit. There will also be upcoming studies using novel cell types which we look forward to using in future clinical trials."
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Stem cell therapy using patient's own cells after heart attack does not enhance cardiac recovery
UPDATE on Stem Cell Therapy 7 November 2012
UPDATE on Stem Cell Therapy
7 November 2012
The Department of Health (DOH) saw the necessity to cover regulations for Stem Cell therapy. Stem Cell therapy belongs to the category of Advanced Cell therapy which includes biologics and blood. Many countries around the world apply a risk-based approach to assess the quality, efficacy and safety of advanced cell therapy. In many countries, Stem Cell is considered an investigational intervention.
Stem Cell research employs both autologous (from same person) or allogenic (from another organism like animal or another human cell or tissue sample) method. Because there are many steps in the preparation of this lab and invasive procedure, there is therefore need to have a regulatory framework to protect Filipino citizens.
Important questions were asked: is there proof of concept in animal trials where stem cell can then be applied in humans? Is there a way to ensure quality and purity of the raw materials? How safe is the procedure? How many did not benefit from the procedure? If this were investigational procedure, how will human subjects be protected?
Sec. Enrique Ona convened a consultative working task force to provide recommendations on how to proceed in the early part of the year in response to queries and mushrooming of centers here and overseas. This led to the creation of a regulatory task force to oversee the appropriate steps that will ensure quality, efficacy and safety documentation of this intervention.
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UPDATE on Stem Cell Therapy 7 November 2012