Heptares Chief Scientific Officer and Founder Fiona Marshall Receives Prestigious UK “Women of Outstanding Achievement …

WELWYN GARDEN CITY, England and BOSTON, November 30, 2012 /PRNewswire/ --

Heptares Therapeutics, the leading GPCR drug discovery company, is delighted to announce that its Chief Scientific Officer and founder, Fiona Marshall, has received a 2012 Women of Outstanding Achievement Award from WISE, a UK national campaign to promote female talent in science, engineering, technology and the built environment. Dr Marshall received the award in the Innovation and Entrepreneurship category in recognition of her academic and industry achievements as well as her positive contributions in attracting women to the life sciences area.

Dr Marshall received her award from Her Royal Highness, The Princess Royal at the prestigious WISE Awards held yesterday at The Institution of Technology and Engineering in London, UK.

"I'm very grateful to receive this award. I have seen Heptares grow from just two of us in a portacabin to a world-leading biotech company with more than 60 scientists, including women from around the world, working in chemistry, crystallography, biochemistry and pharmacology. It has been wonderful to work with so many talented young scientists." commented Dr Marshall. "This team is central to Heptares' leadership in the GPCR field, solving the structures of clinically important GPCRs and leveraging this structural insight to discover and design exciting new drug candidates. Heptares today has a substantial pipeline of unique agents in development for treating serious diseases such as Alzheimer's disease, schizophrenia, chronic insomnia, addiction disorders, migraine and diabetes, as well as partnerships with multiple leading pharmaceutical companies."

Malcolm Weir, Heptares' CEO, added: "Fiona is an exceptional scientist and on behalf of all of us at Heptares, we congratulate her on receiving this award in recognition of her work; it is very well deserved."

Biography

Dr Marshall received a BSc in biochemistry from Bath University and a PhD in neuroscience from Cambridge University. She has more than 20 years' experience in drug discovery with particular expertise on GPCRs, is inventor of seven patents and author of over 60 peer-reviewed scientific papers in the area of GPCRs. Her work has contributed to the development of drugs for asthma, schizophrenia, heart disease and Parkinson's disease.

Dr Marshall set up Heptares Therapeutics, one of the UK's leading biotechnology companies, with Malcolm Weir in 2006. She now leads a team of 60 scientists at Heptares, which is pioneering a structure-based drug design approach to GPCRs and building a broad pipeline of novel medicines to transform the treatment of serious diseases. Heptares has established drug R&D collaborations with Shire, Takeda, AstraZeneca and Medimmune.

Before Heptares, Dr Marshall spent 12 years at GlaxoWellcome/GlaxoSmithKline where she held a number of senior positions including Head of the Department of Molecular Pharmacology and Head of GPCR research. She was Director of Discovery Pharmacology, Europe for Millennium Pharmaceuticals and then spent several years as an independent consultant to a variety of venture capital and biotech companies. She was chair of the BBSRC biochemistry and cell biology committee for three years and is currently Chair of the CRUK Drug Discovery Committee and Vice-chair of the Wellcome Trust Seeding Drug Discovery Committee.

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Heptares Chief Scientific Officer and Founder Fiona Marshall Receives Prestigious UK "Women of Outstanding Achievement ...

Battling bacteria: Research shows iron’s importance in infection, suggests new therapies

(Phys.org)A Kansas State University research team has resolved a 40-year-old debate on the role of iron acquisition in bacterial invasion of animal tissues.

The collaborative researchled by Phillip Klebba, professor and head of the department of biochemistryclarifies how microorganisms colonize animal hosts and how scientists may block them from doing so. The findings suggest new approaches against bacterial disease and new strategies for antibiotic development.

The studyin collaboration with Tyrrell Conway, director of the Microarray and Bioinformatics Core Facilities at the University of Oklahoma, and Salete M. Newton, Kansas State University research professor of biochemistryrecently appeared in PLOS ONE. It shows how iron acquisition affects the ability of bacteria to colonize animals, which is the first stage of microbial disease.

"This paper establishes that iron uptake in the host is a crucial parameter in bacterial infection of animals," said Klebba, the senior author on the publication. "The paper explains why discrepancies exist about the role of iron, and it resolves them."

Iron plays a key role in metabolism, leading bacteria and animals to battle each other to obtain it. Klebba's team found that E. coli must acquire iron from the host to establish a foothold and colonize the guta concept that was often debated by scientists.

"For years it was theorized that iron is a focal point of bacterial pathogenesis and infectious disease because animals constantly defend the iron in their bodies," Klebba said. "Animal proteins bind iron and prevent microorganisms from obtaining it. This is called nutritional immunity, and it's a strategy of the host defense system to minimize bacterial growth. But successful pathogens overcome nutritional immunity and get the iron."

Little was known about what forms of iron enteric bacteriawhich are bacteria of the intestinesuse when growing in the host, but this study shows that the native Gram-negative bacterial iron uptake systems are highly effective. Scientists questioned whether prevention of iron uptake could block bacterial pathogenesis. This article leaves no doubt about the importance of iron when E. coli colonizes animals because bacteria that were systematically deprived of iron became 10,000-fold less able to grow in host tissues, Klebba said.

"This is the first time our experiments unambiguously verified the indispensability of iron in infection, because here we created the correct combination of mutations to study the problem," Klebba said.

Enteric bacteria have so many iron transport systems that it's difficult to eliminate them all. For example, E. coli has at least eight iron acquisition systems.

"These transporters are redundant because iron is essential," Klebba said. "Bacteria are resilient. If one system is blocked, then another one takes over."

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Battling bacteria: Research shows iron's importance in infection, suggests new therapies

Research and Markets: The Biochemistry of the Grape Berry

DUBLIN--(BUSINESS WIRE)--

Research and Markets (http://www.researchandmarkets.com/research/xjlld8/the_biochemistry) has announced the addition of the "The Biochemistry of the Grape Berry" book to their offering.

Grapes (Vitis spp.) are economically significant fruit species. Many scientific advances have been achieved in understanding physiological, biochemical, and molecular aspects of grape berry maturation. Some of these advances have led to the improvement of wine quality through better grape growing practices; but this avenue of research is still wide open due to the complexity of the biochemical mechanisms involved in the development and ripening of grapes and their response to environment.

The Biochemistry of the Grape Berry is a pioneer offering for readers - giving a focused and integrated coverage of the key biochemical and molecular aspects of grape berry development and ripening. Readers will benefit from a comprehensive and updated coverage on key steps, mechanisms and regulation in grapevine biochemistry and molecular biology, provided by an international team of leading scientists. It provides useful references on this research area and original data from laboratories worldwide. The comprehensive range of topics covered in this e-book is valuable to a multidisciplinary readership including plant physiologists, enologists, microbiologists, wine makers, biochemists and students. Thus The Biochemistry of the Grape Berry represents a step forward in the comprehension of grape berry biochemistry, wine quality and health benefits.

Key Topics Covered:

1. Water Relations of the Grape Berry and Aquaporins

2. Mineral Compounds in the Grape Berry

3. Source/Sink Relationships and Molecular Biology of Sugar Accumulation in Grape Berries

4. The Biochemistry of Organic Acids in the Grape

5. Phenolics in Grape Berry and Key Antioxidants

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Research and Markets: The Biochemistry of the Grape Berry

Duke School of Nursing and Winston-Salem State Partner to Increase Minority PhD Candidates

By Duke Medicine News and Communications

DURHAM, NC -- The Duke University School of Nursing and Winston-Salem State University (WSSU) have received a $1.245 million, five-year grant from the National Institutes of Health to increase the number of underrepresented WSSU minority nursing students who are prepared to transition to PhD programs in nursing, and other related biomedical/behavioral science disciplines at Duke University.

Entitled "Bridges to the Doctorate Program," this unique collaboration is the second of its kind in the nation. "Included in our strategic objectives is the goal to promote and develop a diverse group of nurse scientist faculty prepared to lead in the discovery of new knowledge to inform health care. This speaks to the essence of what is the Duke University School of Nursing," said Debra Brandon, Director, of the PhD in Nursing program and Associate Professor. "This is a wonderful opportunity to work with our colleagues at Winston-Salem State University, to create a direct link between their Masters of Nursing Science (MSN) Program and our PhD program at the Duke School of Nursing," she said.

Duke and WSSU will work together to implement a 17-credit hour Research Honors Track within WSSU's MSN program. The enhanced program will consist of early and on-going mentored research experiences, new and strengthened research courses, and a year-long integrated intensive mentored research experience including an intensive eight-week summer research internship at Duke University.

About Duke University School of Nursing

Duke University School of Nursing as a diverse community of scholars and clinicians, educates the next generation of transformational leaders in nursing, advances nursing science in issues of global import, and fosters the scholarly practice of nursing. In 2011, U.S. News and World Report ranked Duke among the top seven graduate schools of nursing in the nation. The National Institutes of Health awarded $4.3 million in research funding to DUSON (Oct.1, 2011, through Sept. 30, 2012), making it one of the top 10 nursing schools engaged with NIH-funded research. The school offers the masters, PhD, and doctor of nursing practice degrees, as well as an accelerated bachelor of science in nursing degree to students who have previously graduated from college. More than 750 students are enrolled in the School of Nursing one of the largest numbers in the school's 80-year history.

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Duke School of Nursing and Winston-Salem State Partner to Increase Minority PhD Candidates

Jumping Hurdles for Behavioral Science – Video


Jumping Hurdles for Behavioral Science
By Troy Daniel Henion Jumping Hurdles This is a song that I am in the process of recording. I only have the guitars done so far. I plan on adding drums and vocals soon. I decided to use this as my creative piece for this project because it shows me in the process of achieving a goal. What are your personal, academic, and professional goals? My personal goals are to gain as much knowledge about the music and entertainment industry as possible and to have a positive impact upon it, and to create an influential, significant, and timeless image of myself in this world through my music. My academic goals are to complete my bachelor #39;s degree in recording arts and move on to a master #39;s degree in entertainment business. My professional goals are to open and run my own recording studio and record label and support artists that are creative and original and to be a prominent recording artist in the industry myself as well. What are the barriers or hurdles you think could hold you back from achieving these goals? What strategies will you use to combat those barriers or hurdles? I think the biggest barrier or hurdle will be my self. I don #39;t believe that anyone else can hold me back from getting what I want because I am too persistent and I want it too much to take no for an answer. I might get distracted easily or not see the point of doing something that doesn #39;t seem directly related to obtaining my goals but for times like these I will take a quick step back to look at the bigger ...From:Troy HenionViews:0 0ratingsTime:02:43More inEducation

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Jumping Hurdles for Behavioral Science - Video

Austin Anti-Aging Medicine: Skin Rejuvenation, Nutritional Support


Austin Anti-Aging Medicine: Skin Rejuvenation, Nutritional Support Weight Loss Programs
As a Fellow in The American Academy of Anti-Aging Medicine, Dr. David Sneed is thoroughly trained in the early detection, prevention, treatment and reversal of age-related dysfunction, disorders and diseases. Dr. Sneed develops Anti-Aging Programs for his Austin patients by testing hormone levels and creating an anti-aging formula based off your blood work results and specific needs. We provide nutritional support by utilizing specific vitamin and nutrient testing so that we can individualize your supplementation program. We also offer fitness assessments and have an on-site dietician who can help customize a weight loss plan that fits your unique needs. Additionally, we have a full-service, non-invasive cosmetic dermatology clinic that is attached with our Austin Family Medicine practice to help you with your skin care and skin rejuvenation needs. To learn more about Austin anti-aging treatments offered at our medical spa, please visit http://www.amedspa.comFrom:DrDavidSneedViews:0 0ratingsTime:03:32More inPeople Blogs

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Austin Anti-Aging Medicine: Skin Rejuvenation, Nutritional Support

Patients Medical Welcomes Dr. Marcia A. Harris, Holistic Gynecologist and Anti-Aging Physician

Leading Integrative Medical Center Offers Hormonal Balancing for Men and Women Looking for Natural Treatment Options

New York City, NY (PRWEB) November 30, 2012

"Dr. Harris comes to us with over 37 years of experience, combining the best of modern technology and science with holistic medicine, said Rashmi Gulati, MD, Medical Director of Patients Medical. Her passion for customer service and excellence in caring for her patients makes her a perfect addition to our multi-disciplinary holistic medical team at Patients Medical.

Like Patients Medical, I am committed to practicing patient-centered medicine, explains Dr. Harris. I spend time getting to know my patients, their unique needs and health concerns. My protocols go beyond typical conventional methods to include extensive nutritional counseling, use of natural supplements, hormonal balancing, herbal remedies and many other progressive treatment plans that are customized for the individual.

Dr. Harris has been practicing in New York City and the surrounding areas, most recently in her private practice, The Life Balance Center, offering her patients a wealth of knowledge using traditional and holistic medicine. She provides her patients with diagnosis and treatment options for menopause, andropause, PMS and PMDD, fibroid tumors, endometriosis, reproductive diseases, STDs, HPV and PCOS. Additionally, she treats secondary conditions that affect mens and womens wellness including obesity, gastro-intestinal and digestive issues, incontinence, immune system issues, fatigue and neuropathy.

Currently, Dr. Harris is offering new patients a $100 coupon, as an incentive to get healthy before the holidays. I want people to enjoy this festive time of year in excellent health, says Dr. Harris.

Dr. Harris graduated with a degree in Chemistry from Pace College, then attended Columbia University College of Physicians and Surgeons on the Rudin Scholarship, where she earned her MD degree. She completed her internship in Internal Medicine at Harlem Hospital Center and residency in Obstetrics and Gynecology at the New York Hospital, Weill Cornell. She is certified by the American Academy of Anti-Aging Medicine (A4M) and in Bio-Identical Hormone Pellet Replacement Therapy.

About Patients Medical

Patients Medical (http://www.patientsmedical.com) is a unique integrative medicine center in Manhattan that combines the best of traditional and holistic medicine with modern technology to provide comprehensive care. Established in 1974, the center employs a multi-specialty staff using leading-edge treatment protocols such as Stem Cell Therapy, Ultraviolet Blood Irradiation, Nutrient IV Therapy, Hyperbaric Oxygen Therapy and more. The practice specializes in diagnosing the root cause of an ailment, then healing the whole person with personalized protocols that draw upon both Eastern and Western medicine.

Megan Franzen Patients Medical 212-679-9667 111 Email Information

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Patients Medical Welcomes Dr. Marcia A. Harris, Holistic Gynecologist and Anti-Aging Physician

'Grey's Anatomy' Postmortem: Sarah Drew and Jesse Williams Talk April and Jackson's Future

ABC

"Grey's Anatomy's" Jesse Williams and Sarah Drew

[Warning: This story contains major spoilers from Thursday's "I Was Made for Lovin' You" episode of Grey's Anatomy.]

While Meredith and Derek celebrated happy news, April and Jackson -- as well as Cristina and Owen -- each suffered major hurdles in their respective relationships during Thursday's Grey's Anatomy.

For Meredith and Derek, the news was good -- she's pregnant! -- but nervous considering this isn't the first time she's been through the process. Cristina and Owen, meanwhile, suffered a major blow when he asks for a divorce after realizing the airline attorneys think the lawsuit will be dismissed because of his conflict of interest with Cristina. While he's clearly doing it out of love for her -- so she can receive the plane crash settlement money -- there's still hope for the duo, unlike Jackson and April.

While Mer and Der celebrated the pregnancy news (our fingers crossed for the tortured couple!), April had the opposite reaction when the unmarried and devout Christian feared she was with child. Naturally caught off-guard by the news, Jackson (Jesse Williams) professes his love for April (Sarah Drew) and declares he's "in" -- as she's more than a casual affair and proposes they get married and start a family, fulfilling April's dream of being "mint to be."

PHOTOS: TV's Leg Up: Amputation Getting Its Hollywood Moment

However, after April celebrates that she dodged a bullet and doesn't have to have a shotgun wedding when she learns she's not pregnant, Jackson takes it personally and opts instead to go the opposite of all in and breaks off the longtime friends' romantic relationship for good (at least for now).

The Hollywood Reporter hit the Hollywood set of the ABC medical drama on Wednesday and got the scoop from Drew and Williams about what's next for the cursed couple.

The Hollywood Reporter: Is there hope for April and Jackson as a couple in the long-term? Jesse Williams: I think so, definitely. It certainly makes it much more interesting and gives it some terrain. This season gives something that started off as really simple with a lot of bumps in the road and this gives them something to miss if they are separate. At the end of this episode, there's just a lot of "could have, would have, should have." There's a lot of ways this could have gone, which leaves you second-guessing and gives you a lot of room to kind of reflect.

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'Grey's Anatomy' Postmortem: Sarah Drew and Jesse Williams Talk April and Jackson's Future

Anatomy of the 12-player Blue Jays-Marlins trade

Anatomy of the 12-player Blue Jays-Marlins trade

By BOB ELLIOTT, QMI Agency

TORONTO - The talks that culminated the 12-player deal between the Miami Marlins and the Toronto Blue Jays reached a crescendo on Nov. 8.

A few days later, the deal was dead.

Pining, passed its sell-by date, totally stiff as a Monty Python parrot.

There were dozens of phone calls, decisions and names exchanged leading to that Nov. 8 meeting at the general managers meetings at Hyatt Regency Resort & Spa in Indian Wells, Calif., and before the deal finally getting done.

Here's a behind-the-scenes look at how all the dominoes fell which sent right-hander Henderson Alvarez, infielders Yunel Escobar and Adeiny Hechavarria, catcher Jeff Mathis, plus minor-leaguers Jake Marisnick, Justin Nicolino and Anthony DeSclafani to south Florida. And starters Josh Johnson, Mark Buehrle, shortstop Jose Reyes, second baseman Emilio Bonifacio and catcher John Buck to the Jays.

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Anatomy of the 12-player Blue Jays-Marlins trade

'Grey's Anatomy's' Sara Ramirez Previews Arizona's Return to Seattle Grace

ABC

"Grey's Anatomy's" Sara Ramirez and Jessica Capshaw

Arizona's road to recovery following the amputation of her left leg has been a rough one on ABC's Grey's Anatomy, but the process received a jump start when Bailey baited her back to Seattle Grace to help with a case.

With the assistance of a prosthetic, Arizona (Jessica Capshaw) took a giant step forward when she indirectly turned her anger about the loss of her limb toward Bailey and angrily made her way to the hospital, bringing a huge smile to her wife Callie's (Sara Ramirez) face in the process. It was the first major positive sign of her return to form that will continue Thursday when she makes her official return to work.

"Initially, Callie's really trying to not get in the way of Arizona's first day back," Ramirez told The Hollywood Reporter during a visit to the Hollywood set Wednesday.

PHOTOS: TV's Leg Up: Amputation Getting Its Hollywood Moment

Callie's support is par for the course this season, which has seen the doc navigate the emotional fallout of a broken promise to Arizona that she would ensure she kept her leg.

"Callie is trying to help from a distance and has some safety nets planted out in case anything goes wrong," Ramirez says. "She's trying to help her wife, but from afar because she doesn't really fully understand what it is her wife needs."

While nobody expects her to be 100 percent back in the saddle immediately -- and in classic Grey's form, not all will be smooth sailing -- Arizona's return will at first feel almost seamless with the peds surgeon also reuniting with Alex, who unbeknownst to Arizona was the one to perform her amputation.

STORY: 'Grey's Anatomy' Recap: Homecomings and Heartbreak

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'Grey's Anatomy's' Sara Ramirez Previews Arizona's Return to Seattle Grace

Primal Pictures Launches Interactive Anatomy Flash Card App for Smart Phones and Computers

The first 3D anatomy flashcard app for mobile devices and computers includes over 1,000 human anatomy images, along with motion, sound and annotations.

London, UK (PRWEB) November 30, 2012

Flash cards have long been a valuable study aid, especially for students preparing for course-related tests and assessment, and medical licensing exams, said Peter Allan, CEO of Primal Pictures. Now as both students and faculty alike turn to online education resources, our digital flash cards provide quick access to high quality anatomy images via the Internet, a smart phone or other portable device.

Primals Interactive Anatomy Flash Cards include more than 1000 fully annotated, full-color, 2D and 3D images pulled from Primal Pictures award-winning 3D Human Anatomy: Regional Edition . Users can view the complete human anatomy, study by structure, or review by regional subsets including:

Each flash card assesses student understanding across a spectrum of topics including: the area of origin, insertion, action, innervation, and anatomical relevance and clinical correlation. Key anatomical structures are uniquely presented through an integrated combination of image, motion and sound bringing the structure to life to optimize student learning. The flash cards can be accessed in a linear manner or cards can seamlessly be shuffled for more randomized review.

Primals Interactive Flash Cards were built in conjunction with Dr. Robert S. Pozos, Ph.D., professor of biology at San Diego State University and CEO of Baja-Education, Inc., an innovative education technology company focused on developing new educational resources using digital approaches.

Faculty and students are increasingly turning to online sources for the course and study materials needed to master anatomy and with the explosion of the smart phones and other portable devices, students want to study and have access to resources while on-the-go. It is critical that faculty and students have the best anatomical content and images possible to make teaching and learning these complex structures more effective, said Peter Allan, CEO of Primal Pictures. Primals Interactive Flash Cards are an engaging and accessible support tool that students will turn to time-and-time again throughout their course and while preparing for exams.

Primal Pictures range of 3D human anatomy titles are already used by more than 500,000 students and 70,000 educators at over 700 colleges and universities around the world. Its flagship product, Anatomy & Physiology Online, was named the best Digital and Online Resource in the British Medical Associations Medical Book Awards.

More information and subscriptions are available at primalpictures.com. Flash card sets are sold individually for $40, with institutional licenses starting at $250.

ABOUT PRIMAL PICTURES

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Primal Pictures Launches Interactive Anatomy Flash Card App for Smart Phones and Computers

Grey's Anatomy Filled With Drama, Joy & Trouble In Relationship Paradise

"Grey's Anatomy" took fans on wild roller coaster of emotions on Thursday night.

Series creator Shonda Rhimes took to Twitter on Thursday to warn fans this week's episode would be a doozy, writing, "WARNING: If you live on the West Coast and don't want the surprise endings of BOTH @GreysABC and @ScandalABC spoiled, SHUT YR COMPUTER DOWN" - and she wasn't kidding!

PLAY IT NOW: Kevin McKidd Dishes On Directing A Silly Episode Of Greys Anatomy

After heartbreaking trouble getting pregnant and eventually adopting baby Zola, it was revealed on Thursday's show that Meredith Grey (played by Ellen Pompeo), is expecting a child. The pregnancy is only three weeks along (so who knows what may happen in ensuing weeks), but it's still exciting news for Meredith and Derek (Patrick Dempsey) - and the fans!

On the opposite end of the happiness scale, Christina (Sandra Oh) and Owen (Kevin McKidd) are going through a definite rough patch in their marriage, and may not be able to bounce back. Owen bluntly told his on-screen ladylove, "We should get a divorce." Even sadder was Christina's equally emotionless response, "If that's what you want."

VIEW THE PHOTOS: The (Formerly) Pregnant Ladies Of Primetime

Racking up points for the happy team was Arizona's successful return to Seattle Grace - as a doctor - for the first time since losing part of her leg on the Season 9 premiere.

Jessica Capshaw, who plays Arizona on the medical drama, was excited to see her character beginning to get back to a normal life.

"Can't wait to see what you all think of Arizona being back at the hospital...as a doctor NOT a patient," the actress Tweeted on Thursday.

VIEW THE PHOTOS: Primetime Hunks: The Hottest Guys On Television!

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Grey's Anatomy Filled With Drama, Joy & Trouble In Relationship Paradise

Africa – Video


Africa
Come with us and experience South Africa.Whether it #39;s a wildlife adventure you #39;re after, or an experience you #39;ll never forget, this is a place where it #39;s possible. Concorde World Travel 5767 Oak Street,Vancouver,BC 604-263-0861From:ConcordeWorldTravelViews:0 0ratingsTime:04:20More inTravel Events

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Africa - Video

Interview of Jeroen A. Bartstra a World Travel Expert – Video


Interview of Jeroen A. Bartstra a World Travel Expert
http://www.universityoftravelexperts.com Jeroen A. Bartstra is a travel expert in Airfare, Visa, Onward Tickets, Immigration. In this interview Andy Lee Graham a perpetual world traveler of 15 years, and 90 countries discusses world travel. He is available for consulting, or travel lectures.From:HoboTravelerViews:13 0ratingsTime:11:45More inTravel Events

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Interview of Jeroen A. Bartstra a World Travel Expert - Video

Aus World Travel – Video


Aus World Travel
#28595; #33775; #26053; #36938;AUS WORLD TRAVEL Official page ~ Perth, Western Australia #25105; #20497; #26371; #35498; #33775; #35486; #12289; #24291; #26481; #35441; #12289; #21360; #23612; #35441; #12289; #39340; #25289; #35441; #12289; #21488; #35486;Our friendly consultants can speak to you in Mandarin, Cantonese, Indonesian, Malay, Taiwanese Mission Best offer for China/Hong Kong/Singapore/Indonesia/Malaysia/Thailand/Vietnam flight tickets ~ Around the World to UK/US/Canada ~ Cruise Specials ~ 20% discount Travel Insurance ~ Student Specials ~ Asian concert News ~ Travelex cash passport ~From:lesliecwleeViews:2 0ratingsTime:00:42More inTravel Events

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Aus World Travel - Video