How the quest to preserve Lenins body helps the living – PBS NewsHour

The most significant and perhaps macabre relic of Soviet Communism resides on Red Square in Moscow. Those hearty enough to enter will be gobsmacked to find a glass sarcophagus containing a superbly preserved body of the controversial leader Vladimir Lenin, comfortably resting in a blue, woolen suit.

Such observances are especially fitting today, the 96th anniversary of his death in 1924.

In the first decades of the last century, this Russian lawyer, radical, political theorist, and social leader whose real name was Vladimir Ilyich Ulyanov took several pages from Karl Marxs work and added his own spin. He led the October Revolution in Russia in 1917, and founded the Soviet Union and the Comintern or Communist International.

Lenin served stormy tenures as head of Soviet Russia from 1917 to 1922 and as head of the Soviet Union from until his death, most likely from a massive stroke, in 1924. He was only a few months shy of his 54th birthday.

Nearly a century later, a team of anatomists, biochemists, and surgeons work around the clock to maintain what remains of Lenins body.

Nearly a century later, a team of anatomists, biochemists, and surgeons work around the clock to maintain what remains of Lenins body. Called the Mausoleum group, they work at the Moscow Center for Scientific Research and Teaching Methods in Biochemical Technologies.

From the 1920s until 1991, preserving Lenins body was a scientific priority for the former Soviet Union. During this period, the Mausoleum group consisted of more than 200 scientists and technicians. Since the fall of Communism in the 1990s, however, the funding and staffing has dropped considerably. To help make ends meet, the same group conducts other research and maintains the well-preserved bodies of Ho Chi Minh of Vietnam and Kim Il-Sung and Kim Jong-Il of North Korea.

Alexei Yurchak, a professor of anthropology at the University of California, Berkeley, has helped illuminate these processes and the discoveries that come from them in his writings, including a 2015 paper called Bodies of Lenin: The hidden science of communist sovereignty.

On the day Lenin died, his successors began planning a state funeral and ceremonial burial. Lenin and his family were quite firm in their requests not to create a sense of hero worship around his memory. Indeed, his wife Nadezhda Krupskaya wrote in the Jan. 30, 1924 issue of the Pravda newspaper: I have a big favor to ask of you; do not let your grief for Ilich go into the external adoration of his personality. Do not erect monuments to him, build palaces in his name, organize magnificent ceremonies is his memory to all this he, during his lifetime, paid so little attention. All this was a burden to him.

Lenins body was placed on view for about a week. Because of the extremely cold temperatures in Moscow that year, the undertakers were amazed to note how little deterioration there was in his corpse. They went as far as to predict that decomposition would not become a problem until the warmer temperatures of spring.

This frozen state gave the party leadership a much longer period to consider what to do with Lenins body. Many were opposed to doing anything more than a burial in Red Square. Other party members, however, pointed to the long lines of people who still wanted to bid farewell to their leader; more than 500,000 people had already queued up to pay their respects. After much discussion, the Party collectively decided that a tomb containing Lenins body should become a site of world pilgrimage for the working class.

In March of 1924, Vladimir Vorobev, a physician, and Boris Zbarskii, a biochemist, of the Moscow Medical Institute, were asked to apply their newly developed biochemical method of embalming on Lenins body. By July, they were able to report that the corpse could remain in good shape indefinitely, as long as it was re-embalmed and cared for at regular intervals. This discovery represented a smashing success for Soviet science.

Thus, the corpse of Lenin was transformed from the remains of a once-living person into a monument to the Russian Revolution and the Communist way of life. Even today, nearly 30 years after the demise of the U.S.S.R., Lenins Mausoleumjust beyond the foreboding walls of the Kremlin and heavily protected by a goose-stepping honor guardremains one of Moscows most visited tourist sites. Last year, more than 2.5 million people entered the carefully monitored and environmentally controlled tomb.

All that is preserved of Lenins body, incidentally, is his skeleton, skin, muscle tissues, and outward form. His vital organs and his brain were all removed for study at autopsy, directly upon his death.

Armchair pathologists, by the way, are still arguing over whether Lenin died of a stroke or the neurological complications of tertiary syphilisor both. During his final months, he demonstrated many symptoms of neuro-syphilis, including terrible headaches, seizures, nausea, insomnia and partial paralysis. Lenin may also have been briefly dosed with Salvarsan, the arsenical compound developed by Dr. Paul Ehrlich in 1909 to treat syphilis in the pre-antibiotic era.

Unfortunately, we may never know the precise answer, unless the Moscow Institute of the Brain releases their precise post-mortem findings. Until then, the autopsy slices of Lenins brain remain locked away.

During the 1924 autopsy, the pathologists also removed all of Lenins arteries and veins. Thus, the preservation team could not infuse embalming fluids through those vesselsthe most common way to deliver such chemicals through a body. Instead, they developed micro-injection techniques where individual hypodermic syringes filled with embalming agents were injected directly into the portion of the body that required preservation at any given time. They also invented a two-layered rubber suit to fit over the corpse in order to keep a thin layer of embalming agents circulating around his body at all times. The dark, business suit Lenin currently wears was specifically tailored to fit over the rubber suit.

You dont have to be an admirer of Lenin to appreciate the stunning visual impression achieved by his keepers.

Every other year, the entire corpse is re-embalmed by submerging it in several different solutions: glycerol, formaldehyde, potassium acetate, alcohol, hydrogen peroxide, acetic acid, and acetic sodium. Each submersion takes about six weeks.

Lenins body is constantly under surveillance for areas of deterioration and immediate repair. Painstaking attention is paid to the corpses external features. According to Yurchaks findings, Lenin now has artificial eyelashes because his were damaged in an early embalming process. His nose, face, eye sockets, and several other parts of his body have been re-sculpted, with a material made of paraffin, glycerin and carotene, to help keep his facial appearance close to its original, and far more lively, look. You dont have to be an admirer of Lenin to appreciate the stunning visual impression achieved by his keepers.

Over the last century, the Lenin preservation laboratory has created a long list of biological preservation techniques. Yurchak also documented how these scientists have developed many measures that help living people, including new equipment designed to keep blood flowing through donor kidneys prior to their transplantation and even a noninvasive skin test to measure cholesterol.

All this is to say that while Lenin has been dead almost twice as long as he lived, a great deal of science, public history, political theater and fascination has been generated by what remains in Moscow today.

Editors note: This story has been updated to reflect the contributions of the scholarship by Alexei Yurchak.

More here:
How the quest to preserve Lenins body helps the living - PBS NewsHour

Can we use the brain’s ‘biochemical changes’ to predictand prevent suicide? – Genetic Literacy Project

No field of scientific inquiry can single-handedly untangle a phenomenon as complex as suicide. But [Kees] van Heeringen and many other scientists are hoping to shed light on the problem by digging into the neurobiological processes underlying thoughts about ending ones own life and attempts to do so. This work is building support for the idea that suicide is tied to specific biochemical changes that can be measured and targeted independently of, and possibly in parallel with, the mental health disorders they often accompany. Findings from this work, researchers hope, could help reveal new treatments, and perhaps even opportunities to identify the people most at risk in time to intervene.

[Psychiatric genetic epidemiologist Nadine] Melhem says shes hopeful that combining techniques will improve predictive approaches in the coming years. In 2019, she and colleagues published amodelthat improved on the accuracy and performance of existing models to predict suicide attempts based on factors such as the severity and variability of a persons depression symptoms over time. Integrating this sort of easy-to-collect clinical data with biological information from brain scans or other diagnostic tests should lead to more-accurate predictions, she says.

Read the original post here

Follow this link:
Can we use the brain's 'biochemical changes' to predictand prevent suicide? - Genetic Literacy Project

Drug Could Offer New Option Against Lupus – HealthDay

THURSDAY, Dec. 19, 2019 (HealthDay News) -- People suffering from the autoimmune disease lupus might soon have a new drug to turn to, a clinical trial suggests.

Anifrolumab is a lab-created antibody that blocks type 1 interferon, a biochemical that activates an immune response in humans, explained lead researcher Eric Morand, head of the Monash Health School of Clinical Sciences in Melbourne, Australia.

The new drug triggered a significant reduction in lupus symptoms in 48% of patients after one year, compared with 32% of patients receiving a placebo.

"We've known for a long time that about 80% of lupus patients have a detectible signature in their blood showing they have too much interferon in their system," Morand said.

Anifrolumab, which blocks the type 1 interferon receptor that all immune cells share, shows that overproduction of this biochemical does indeed play a major role in lupus, he said.

"This drug, which does only that one thing, was associated with a dramatic improvement in patients' outcomes compared to placebo," Morand said.

Based on results from this and earlier trials, pharmaceutical company AstraZeneca intends to file for U.S. approval of anifrolumab sometime within the first half of next year, Morand said.

"They feel optimistic because across all three trials, virtually all of the measures stack up and look the same," he said.

AstraZeneca funded this trial.

About 1.5 million people in the United States have lupus, and more than 5 million worldwide have it, researchers said in background notes. Nine out of 10 patients with lupus are women.

Lupus causes the immune system to turn against the body, causing inflammation and pain. People most commonly suffer from rash, painful or swollen joints, headaches, extreme fatigue, anemia, fever and swelling in the feet, legs and hands, according to the Lupus Foundation of America.

Lupus also causes sustained inflammation in the internal organs, and about 10% of people diagnosed with the disease die within a decade, researchers said.

In this international three-year clinical trial, half of 362 patients received anifrolumab and the other half received a placebo.

An earlier clinical trial of anifrolumab did not return positive results because doctors had set a goal of total improvement in at least one organ system affected by lupus, Morand said.

This trial shifted the goal posts, instead aiming for partial but significant improvement across all the organ systems being harmed by lupus, he said.

Researchers said the drug met that goal. For example, many patients with a lupus-provoked rash found that their skin cleared after starting anifrolumab.

"The most obvious improvements were in severe lupus skin disease. It's obvious because you and the patient can both see it," Morand said. "There are many reports from investigators of skin disease almost vanishing swiftly."

Patients also needed fewer doses of steroids to treat their symptoms, and experienced symptom flares less frequently.

No one had to stop taking anifrolumab due to side effects, which were mainly caused by the drug's inhibition of immune response against viral infections, Morand said. About 7% of patients suffered an outbreak of shingles and 12% came down with bronchitis.

However, there was one death from pneumonia in the group taking anifrolumab.

The findings were published Dec. 18 in the New England Journal of Medicine.

"There's been very little good news in lupus for a long, long time," Morand said, noting that the trial results show that "we're learning how to do this better, and hopefully more drugs will succeed in the coming years."

An editorial published with the study noted that across three clinical trials, results for most of the primary and secondary goals showed that anifrolumab did perform better than a placebo.

"Given the need to bring drugs to patients with SLE [systemic lupus erythematous], the lupus community has urged regulators to consider trial designs that allow greater flexibility in defining success," wrote editorialists Dr. Jane Salmon from Weill Cornell Medicine and Dr. Timothy Niewold from NYU School of Medicine, both in New York City.

"Such strategies might accelerate drug development in lupus until we have available universally accepted response measures and biomarkers that allow grouping of patients with SLE according to biologic pathways that drive their disease," the editorial concluded.

More information

The Lupus Foundation of America has more about lupus.

SOURCES: Eric Morand, Ph.D., head, Monash Health School of Clinical Sciences, Melbourne, Australia; Dec. 19, 2019, New England Journal of Medicine

Continued here:
Drug Could Offer New Option Against Lupus - HealthDay

OSU scientists replace mice genes to study vitamin Ds effects on infections – The Register-Guard

By giving mice a human gene that helps fight infections, Oregon State University scientists have made a new model to show the impacts of vitamin D on staph infections.

Research from Oregon State University has shown a new model suggesting vitamin D treatment can dramatically reduce the quantity of disease-causing bacteria in skin wounds.

OSU scientist Adrian Gombart and his collaborators in the past have examined the vitamin's role in fighting infection, but in their new study mice were given a human gene that provides a barrier against infections and is promoted by the bioactive form of vitamin D.

Mice naturally have a similar gene, but vitamin D does not trigger it. The scientists replaced the mouse gene, called Camp, with the human gene, called CAMP, which gave the mice increased resistance to gut and staph infections, caused by the bacterium Staphylococcus aureus, when vitamin D was introduced.

Vitamin D3 regulates the expression of the CAMP, and Staphylococcus aureus is an important human pathogen that causes skin infections, Gombart said in a news release. With our mouse model, we showed that treating a skin wound infected with S. aureus with the bioactive form of vitamin D significantly reduced the number of bacteria in the wound.

Vitamin D, which is fat-soluble and present in very few foods, promotes calcium absorption in the gut and is needed for bone growth. Vitamin D, manufactured by the body when triggered by sunlight, is also important for cell growth, neuromuscular function, and reduction of inflammation.

The scientists believe their new model will be useful as research into vitamin D-induced expression of CAMP progresses, involving diseases caused by microorganisms and also conditions that are non-pathogenic, such as inflammatory bowel disease.

The finding, Gombart said, suggests vitamin D can be used to increase protection against infection by increasing CAMP levels. Those findings recently were published in the Journal of Steroid Biochemistry and Molecular Biology.

Here is the original post:
OSU scientists replace mice genes to study vitamin Ds effects on infections - The Register-Guard

Biochemical Diagnostic Reagent Market Scope 2020 to 2026 with industry Growth Factors, Size, Share, Key Players, Trends and Top Regions – Fusion…

New market research report on global Biochemical Diagnostic Reagent market 2020 with industry growth analysis, size, share, trends and forecast 2026 is made available by QY Research.

The global Biochemical Diagnostic Reagent market is broadly and deeply studied in the report with key focus on the competitive landscape, regional growth, market segmentation, and market dynamics. We have used latest primary and secondary research techniques for compiling this comprehensive research study. The report offers Porters Five Forces analysis, PESTLE analysis, competitive analysis, manufacturing cost analysis, revenue and production analysis, and various other types of analysis to provide a complete view of the global Biochemical Diagnostic Reagent market. Each segment of the global Biochemical Diagnostic Reagent market is carefully analyzed on the basis of market share, CAGR, and other vital factors. The global Biochemical Diagnostic Reagent market is also statistically presented with the help of Y-o-Y growth, CAGR, revenue, production, and other important calculations.

Get the Sample of this [emailprotected]https://www.qyresearch.com/sample-form/form/1458263/global-biochemical-diagnostic-reagent-market

We can customize the report as per your requirements. Our analysts are experts in market research and analysis and have a healthy experience in report customization after having served tons of clients to date. The main objective behind preparing the research study is to inform you about future market challenges and opportunities. The report is one of the best resources you could use to secure a strong position in the global Biochemical Diagnostic Reagent market.

Market Segmentation:

Following are the segments covered by the report are:Liquid Double ReagentDry Powder Double Reagent

By Application:HospitalClinicLaboratory

Key Players:The Key manufacturers that are operating in the global Biochemical Diagnostic Reagent market are:RocheSiemens HealthineersBeckman CoulterRandoxBioSinoBeijing Leadman BiochemistryFosunPharmaBeijing Strong BiotechnologiesDojindo LaboratoriesSysmexKAINOS LaboratoriesDAAN Gene

Regional GrowthThe report offers in-depth analysis of key regional and country-level Biochemical Diagnostic Reagent markets, taking into account their market size, CAGR, market potential, future developments, and other significant parameters. The Middle East and Africa (GCC Countries and Egypt) North America (the United States, Mexico, and Canada) South America (Brazil etc.) Europe (Turkey, Germany, Russia UK, Italy, France, etc.) Asia-Pacific (Vietnam, China, Malaysia, Japan, Philippines, Korea, Thailand, India, Indonesia, and Australia)

Key Questions Answered What will be the size and CAGR of the global Biochemical Diagnostic Reagent market in 2025? Which product will gain the highest demand in the global Biochemical Diagnostic Reagent market? Which application could show the best growth in the global Biochemical Diagnostic Reagent market? What will be the nature of the competitive landscape in future? Which players will lead the global Biochemical Diagnostic Reagent market in the coming years? Which region will gain the largest share of the global Biochemical Diagnostic Reagent market?

Get Customized Report in your Inbox within 24 hours @https://www.qyresearch.com/customize-request/form/1458263/global-biochemical-diagnostic-reagent-market

Table of Contents

Report Overview: It includes six chapters, viz. research scope, major manufacturers covered, market segments by type, Biochemical Diagnostic Reagent market segments by application, study objectives, and years considered.

Global Growth Trends: There are three chapters included in this section, i.e. industry trends, the growth rate of key producers, and production analysis.

Biochemical Diagnostic Reagent Market Share by Manufacturer: Here, production, revenue, and price analysis by the manufacturer are included along with other chapters such as expansion plans and merger and acquisition, products offered by key manufacturers, and areas served and headquarters distribution.

Market Size by Type: It includes analysis of price, production value market share, and production market share by type.

Market Size by Application: This section includes Biochemical Diagnostic Reagent market consumption analysis by application.

Profiles of Manufacturers: Here, leading players of the global market are studied based on sales area, key products, gross margin, revenue, price, and production.

Biochemical Diagnostic Reagent Market Value Chain and Sales Channel Analysis: It includes customer, distributor, Biochemical Diagnostic Reagent market value chain, and sales channel analysis.

Market Forecast Production Side: In this part of the report, the authors have focused on production and production value forecast, key producers forecast, and production and production value forecast by type.

About Us:QYResearch always pursuits high product quality with the belief that quality is the soul of business. Through years of effort and supports from huge number of customer supports, QYResearch consulting group has accumulated creative design methods on many high-quality markets investigation and research team with rich experience. Today, QYResearch has become the brand of quality assurance in consulting industry.

More here:
Biochemical Diagnostic Reagent Market Scope 2020 to 2026 with industry Growth Factors, Size, Share, Key Players, Trends and Top Regions - Fusion...

Biochemical Sensor Market to Witness Heightened Growth During the Period 2018 2025 – Guru Online News

Latest posts by Ethan Taylor (see all)

The competition prevailing in the global biochemical sensor market is considerably high. As leading companies fight out for the lead in the market, product innovations and launches are on cards. Besides this, investments in research and development have scaled higher as market players aim for emerging at the fore. In order to boost operations, several players are concentrating on expanding their regional footprint, especially in Asia Pacific. Cheap labor, abundance of raw materials, and the rising demand from emerging nations make the region highly lucrative for investment, finds Trends market research(TMR) in a Recent study.

Some of the most prominent names in the global biochemical sensor market are GE Healthcare, Thermo Fisher Scientific, Honeywell International, Inc., Bio-Rad Laboratories, Inc., and Polestar Technologies, Inc., among others. Besides aforementioned strategies, many of the market players are also pushing mergers and acquisitions to capitalize on their expertise and expand their product portfolio.

Overall, the globalbiochemical sensor marketwill rise at a healthy CAGR of XX% by 2025. At this pace, the market is expected to reach US$XX bn by the end of 2025, from its valuation of US$XX bn in 2016. Based on product, electrochemical sensors constituted the leading segment with a share of XX% in 2016. Besides this, piezoelectric sensor, thermal sensor, gas sensor, and optical sensor make other key segments in terms of product.

Request For Report sample @:https://www.trendsmarketresearch.com/report/sample/3433

Regionally, North America held dominant with a share of over XX% in the global market in 2018. Europe and Asia Pacific followed closely as the second- and third-leading markets for biochemical in the same year. However, over the course of the forecast period, North America is likely to lose its market share, while Asia Pacific and Europe markets will witness accelerated pace of gains.

Application across Diverse Industries, Especially Healthcare, to Boost Growth

As biochemical sensors have found a leading end user in the healthcare sector, growth witnessed in the industry will subsequently fuel their demand. The healthcare infrastructure is a major consideration by governments when planning economic growth. Over the years, the industry has expanded exponentially. Additionally, investments in research and development are forecast to increase in the coming years.

Request Report For Toc:https://www.trendsmarketresearch.com/report/requesttoc/3433

Biochemical sensors are used in the qualitative and quantitative assessment of clinical diagnosis in the healthcare sector, said a lead TMR analyst. The increasing aging population, coupled with the rising incidence of chronic ailments, will fuel the demand for precise diagnosis, thus providing significant impetus to the biochemical sensor market, he added.

Besides this, government initiatives to ensure superior food quality, advancements in material chemistry and wireless networks, the rising demand for advanced wearable biochemical sensors, and the growing population of point of care diagnostics will create lucrative market opportunities. RRI also prophesized that the rising oil extraction worldwide will tip scales in favor of the market. Rise in oil extraction would result in greater percentage of inflammable and toxic in the air. Spurred by this, the use of biochemical sensors will increase to detect the presence of toxic gas.

Full View ofReport Description:https://www.trendsmarketresearch.com/report/biochemical-sensor-market

View More:Electronics & Semiconductor

See the original post here:
Biochemical Sensor Market to Witness Heightened Growth During the Period 2018 2025 - Guru Online News

Global Automated Biochemistry Analyzers Market 2019 by Manufacturers, Regions, Type and Application, Forecast to 2025 – The Industry Press Releases

The global "Automated Biochemistry Analyzers Market" research report comprises of the basic insights that are relevant to the global market. The report being an all-inclusive one will be of great help to the users in order to understand not only the market trends, but also the size, forecast trends, production, share, demand, sales, and many such aspects.

Ask for sample link here: http://www.marketresearchstore.com/report/global-automated-biochemistry-analyzers-market-2018-by-manufacturers-391926#RequestSample

What Global Automated Biochemistry Analyzers Market Research Report Consists?

Inquire about the report here: http://www.marketresearchstore.com/report/global-automated-biochemistry-analyzers-market-2018-by-manufacturers-391926#InquiryForBuying

Additional Points Covered In The Report

Set of Chapters:

1. Automated Biochemistry Analyzers Market outline

2. International Automated Biochemistry Analyzers market Followed by makers

3. world Automated Biochemistry Analyzers Market capability, Generation, Sales (Worth ) by Region (2019-2028)

4. world Automated Biochemistry Analyzers Market provide (Production), Presence, Export, printed by Region (2019-2028)

5. International Automated Biochemistry Analyzers market Production, Revenue (Worth ), value Trend by kind

6. International Automated Biochemistry Analyzers marketing research by Application

7. Automated Biochemistry Analyzers Market makers Profiles/Analysis

8. Automated Biochemistry Analyzers Market producing analysis

9. Industrial Chain, Best Sourcing Strategy and Down-stream consumers

10. Marketing-strategy Analysis, Distributors/Traders

11. Market result sides designation

12. World Wide Automated Biochemistry Analyzers Market Forecast (2019-2028)

13. Automated Biochemistry Analyzers research Findings and call

14. Appendix

Research Objective :

Our panel of trade contributors moreover as trade analysts across the worth chain have taken vast efforts in doing this group action and heavy-lifting add order to produce the key players with useful primary & secondary data concerning the world Automated Biochemistry Analyzers market. additionally, the report additionally contains inputs from our trade consultants that may facilitate the key players in saving their time from the interior analysis half. firms WHO get and use this report are going to be completely profited with the inferences delivered in it. except this, the report additionally provides an in-depth analysis of Automated Biochemistry Analyzers sales moreover because of the factors that influence the shoppers moreover as enterprises towards this method.

Thanks for reading this article; you'll be able to additionally get individual chapter wise sections or region wise report versions like North America, Europe, Asia-Pacific, South America, geographic area and continent.

Sorry! The Author has not filled his profile.

Read the original here:
Global Automated Biochemistry Analyzers Market 2019 by Manufacturers, Regions, Type and Application, Forecast to 2025 - The Industry Press Releases

Biochemistry | IntechOpen

Biochemistry | IntechOpen

Open access peer-reviewed Edited Volume

Over the recent years, biochemistry has become responsible for explaining living processes such that many scientists in the life sciences from agronomy to medicine are engaged in biochemical research. This book contains an overview focusing on the research area of proteins, enzymes, cellular mechanisms and chemical compounds used in relevant approaches. The book deals with basic issues and some of...

Over the recent years, biochemistry has become responsible for explaining living processes such that many scientists in the life sciences from agronomy to medicine are engaged in biochemical research. This book contains an overview focusing on the research area of proteins, enzymes, cellular mechanisms and chemical compounds used in relevant approaches. The book deals with basic issues and some of the recent developments in biochemistry. Particular emphasis is devoted to both theoretical and experimental aspect of modern biochemistry. The primary target audience for the book includes students, researchers, biologists, chemists, chemical engineers and professionals who are interested in biochemistry, molecular biology and associated areas. The book is written by international scientists with expertise in protein biochemistry, enzymology, molecular biology and genetics many of which are active in biochemical and biomedical research. We hope that the book will enhance the knowledge of scientists in the complexities of some biochemical approaches; it will stimulate both professionals and students to dedicate part of their future research in understanding relevant mechanisms and applications of biochemistry.

Open access peer-reviewed

By Spyridoula N. Charova, Anastasia D. Gazi, Marianna Kotzabasaki, Panagiotis F. Sarris, Vassiliki E. Fadouloglou, Nickolas J. Panopoulos and Michael Kokkinidis

Open access peer-reviewed

By Lifeng Cai, Weiguo Shi and Keliang Liu

Open access peer-reviewed

By Mohammad T. Elnakish and Hamdy H. Hassanain

Open access peer-reviewed

By Baks Laura, Mat Sabina, Vazquez Romina and Herlax Vanesa

Open access peer-reviewed

By Ana M. Sotoca, Jacques Vervoort, Ivonne M.C.M. Rietjens and Jan-ke Gustafsson

Open access peer-reviewed

By Waelbroeck Magali

Open access peer-reviewed

By Kazunori Namba

Open access peer-reviewed

By Maria Giulia Lionetto, Roberto Caricato, Maria Elena Giordano, Elisa Erroi and Trifone Schettino

Open access peer-reviewed

By Con Dogovski, Sarah. C. Atkinson, Sudhir R. Dommaraju, Matthew Downton, Lilian Hor, Stephen Moore, Jason J. Paxman, Martin G. Peverelli, Theresa W. Qiu, Matthias Reumann, Tanzeela Siddiqui, Nicole L. Taylor, John Wagner, Jacinta M. Wubben and Matthew A. Perugini

Open access peer-reviewed

By Jana Viskupicova, Miroslav Ondrejovic and Tibor Maliar

Open access peer-reviewed

By Lei Zheng, Jiangtao Li and Yan Luo

Open access peer-reviewed

By Tatsuaki Tsuruyama

Open access peer-reviewed

By Renjitha Pillai and Jamie W. Joseph

Open access peer-reviewed

By Mitsushi J. Ikemoto and Taku Arano

Open access peer-reviewed

By Kuo-Hsiang Tang

Open access peer-reviewed

By Yasunori Watanabe and Nobuo N. Noda

Open access peer-reviewed

By Alberto Ouro, Lide Arana, Patricia Gangoiti and Antonio Gomez-Muoz

Open access peer-reviewed

By J. Thomas, T.P. Shentu and Dev K. Singh

Open access peer-reviewed

By Ivo Juranek, Lucia Rackova and Milan Stefek

Free shipping with DHL Express

Hardcover (ex. VAT)170

Residents of European Union countries need to add a Book Value-Added Tax of 5%. Institutions and companies, registered as VAT taxable entities in their own EU member state, will not pay VAT by providing IntechOpen with their VAT registration number. This is made possible by the EU reverse charge method.

All IntechOpen contributors are offered special discounts starting at 40% OFF available through your personal dashboard

Among the alkaline and/or alkaline-earth oxides, various lithium, sodium, potassium, calcium and magnesium ceramics have been proposed for CO2 capture through adsorption and chemisorption processes [1-20]. These materials can be classified into two large groups: dense and porous ceramics. Dense ceramics mainly trap CO2 chemically: the CO2 is chemisorbed. Among these ceramics, CaO is the most studied one. It presents very interesting sorption capacities at high temperatures (T 600 C). In addition to this material, alkaline ceramic oxides have been considered as possible captors, mostly lithium and sodium based ceramics (Li5AlO4 and Na2ZrO3, for example). In these cases, one of the most interesting properties is related to the wide temperature range in which some of these ceramics trap CO2 (between 150 and 800 C), as well as their high CO2 capture capacity.

In these ceramics, the CO2 capture occurs chemically, through a chemisorption process. At a micrometric scale, a general reaction mechanism has been proposed, where the following steps have been established: Initially, CO2 reacts at the surface of the particles, producing the respective alkaline or alkaline-earth carbonate and in some cases different secondary phases. Some examples are:

The above reactions show that surface products can be composed of carbonates, but as well they can contain metal oxides or other alkaline/alkaline-earth ceramics. The presence of these secondary phases can modify (improve or reduce) the diffusion processes described below [1].

Once the external carbonate shell is formed, different diffusion mechanisms have to be activated in order to continue the CO2 chemisorption, through the particle bulk. Some of the diffusion processes correspond to the CO2 diffusion through the mesoporous external carbonate shell, and some others such as the intercrystalline and grain boundary diffusion processes [1, 18, 21].

Figure 1 shows the theoretical CO2 chemisorption capacities (mmol of CO2 per gram of ceramic) for the most studied alkaline and alkaline-earth ceramics. As it can be seen, metal oxides (Li2O, MgO and CaO) are among the materials with the best CO2 capture capacities. Nevertheless, Li2O and MgO have not been really considered as possible options due to reactivity and kinetics factors, respectively. On the contrary, CaO is one of the most promising alkaline-earth based materials, with possible real industrial applications. Other interesting materials are ceramics with lithium or sodium phases, which present better thermal stabilities and volume variations than CaO. In addition, the sodium phases may present another advantage if the CO2 capture is produced in the presence of steam. Under these conditions the sodium phases may produce sodium bicarbonate (NaHCO3) as the carbonated phase, which is twice the amount of CO2 could be trapped in comparison to the Na2CO3 product.

Theoretical CO2 capture capacities for different alkaline and alkaline-earth ceramics. In the Li8SiO6 (labeled as *) and Li4SiO4 (labeled as +), the maximum capacity can depend on the CO2 moles captured in each different phase formed (Li8SiO6 + CO2 Li4SiO4 + CO2 Li2SiO3 + Li2CO3).

Other ceramics containing alkaline-earth metals are the layered double hydroxides (LDH) or hydrotalcite-like compounds (HTLc). LDHs, also called anionic clays due to their layered structure and structural resemblance to a kind of naturally-occurring clay mineral. These materials are a family of anionic clays that have received much attention in the past decades because of their numerous applications in many different fields, such as antacids, PVC additives, flame retardants and more recently for drug delivery systems and as solid sorbents of gaseous pollutants [22-24]. The LDH structure is based on positively charged brucite like [Mg(OH)2] layers that consist of divalent cations surrounded octahedrally by hydroxide ions. These octahedral units form infinite layers by edge sharing [25]. Due to the fact that certain fraction of the divalent cations can be substituted by trivalent cations at the centers of octahedral sites, an excess of positive charge is promoted. The excess of positive charge in the main layers of LDHs is compensated by the intercalation of anions in the hydrated interlayer space, to form the three-dimensional structure. These materials have relatively weak bonds between the interlayer and the sheet, so they exhibit excellent ability to capture organic or inorganic anions. The materials are easy to synthesize by several methods such as co-precipitation, rehydration-reconstruction, ion exchange, hydrothermal, urea hydrolysis and sol gel, although not always as a pure phase [26].

The LDH materials are represented by the general formula: [M1-xIIMxIII(OH)2]x+[Am]x/mnH2Owhere MII and MIII are divalent (Mg2+, Ni2+, Zn2+, Cu2+, etc.) and trivalent cations (Al3+, Fe3+, Cr3+, etc.), respectively, and Am- is a charge compensating anion such as CO32-, SO42-, NO3-, Cl-, OH-, where x is equal to the molar ratio of [MIII/(MII + MIII)]. Its value is commonly between 0.2 and 0.33, i.e., the MII/MIII molar ratio is in the range of 4 - 2 [25], but this is not a limitation ratio and it depends on the MII and MIII composition [27-29].

Among various CO2 mesoporous adsorbents, LDH-base materials have been identified as suitable materials for CO2 sorption at moderate temperatures (T 400 C) [30-46] due to their properties such as large surface area, high anion exchange capacity (2-3 meq/g) and good thermal stability [37-40]. The LDH materials themselves do not possess any basic sites. For that reason, it is preferred to use their derived mixed oxides, formed by the thermal decomposition of LDH, which do exhibit interesting basic properties. Thermal decomposition of the material occurs in three stages, first at temperatures lower than 200 C, at which the dehydration of superficial and interlayer water molecules takes place on the material. Then the second decomposition stage takes place in the range of 300-400 C, at which the structure collapses due to a partial dehydroxylation process, typically associated with both the decomposition of Al-OH and the Mg-OH hydroxides. During dehydroxylation, changes occur in the structure. A portion of the trivalent cations of the brucite like layers migrates to the interlaminar region, allowing the preservation of the laminar characteristics of the material [41]. Finally, the total decomposition of the material occurs at temperatures higher than 400 C, when the decarbonation process is completed [42].

Once the temperature reaches about 400 C, LDH forms a three-dimensional network of compact oxygen with a disordered distribution of cations in the interstices, where the cations M+3 are tetrahedrally coordinated (interlayer region) and M+2 are octahedrally coordinated. The compressive-expansion stresses associated with the formation of the amorphous three-dimensional networks and their connection to the octahedral layer increases the surface area and pore volume, which can help improve the storage capacity properties, for example for gas sorption related applications, besides decreasing the ability of the Mg+2 cation to favor physisorption instead of chemisorption [30, 42]. For instance, the thermal evolution of the Mg/Al-CO3 LDH structure is considered to be crucial in determining the CO2 adsorption capacity, so there are several studies about this issue [42-44].

Reddy et al. [43] studied the effect of the calcination temperature on the adsorptive capacity of the Mg/Al-CO3 LDH. They found out that the best properties were obtained at calcination temperature of 400 C, which they attributed to the obtaining of a combination of surface area and the availability of the active basic sites. Actually, at this temperature the material is still amorphous, which allows having a relatively high surface area. Therefore, there is a high number of exposed basic sites, allowing the reversible CO2 adsorption according to the following reaction:

However, if the LDH is calcined under 500 C, the material is able to transform back to the original LDH structure when it is exposed to a carbonate solution or another anionic containing solution. Finally, if the sample is heated to temperatures above 500 C, the structural changes become irreversible because of the spinel phase formation [37].

As mentioned, the mixed oxides derived from the LDH calcination possess some interesting characteristics such as high specific surface area, excess of positive charge that needs to be compensated, basic sites and thermal stability at elevated temperatures (200 400 C). Besides these aspects, it is important to consider the advantage of acid-base interactions on the CO2 sorption applications, where acidic CO2 molecules interact with the basic sites on the derived oxide. These characteristics make the LDH-materials acceptable CO2 captors [43, 45]. However, the CO2 adsorption capacity of this material is low compared with other ceramic sorbents; reaching mean values smaller than 0.1 mmol/g [46]. Nevertheless, many studies suggest that the adsorption capacity of LDH materials can be improved by modifying a factor set such as: composition, improvement of the materials basicity and contaminant gas stream composition [30-32, 36, 41-45, 47-59].

As previously mentioned, Reddy et al. [43] studied the influence of the calcination temperature of LDHs on their CO2 capture properties. The Mg3/Al1-CO3 material was calcined at different temperatures ranging from 200 to 600 C. The results showed that when the calcination temperatures are under 400 C, LDH is considered to be dehydrated and materials still keep the layered structure intact, wherein the CO32- ions are occupying the basic sites. The obtained samples calcined at 400 C have the maximum BET surface area of 167 m2/g compared with samples calcined at lower temperatures. Moreover, during the calcination of the LDH at higher temperatures (T > 500 C), most of the CO32- decompose to release some basic sites for CO2 adsorption. However, the final amount of basic sites decreases with the subsequent crystallization of the MgO and spinel (MgAl2O4). Hence, LDH materials obtained at 400 C have the highest surface area and the maximum quantities of active basic sites exposed. Because of these characteristics, they achieved a total sorption capacity of 0.5 mmol/g [43]. The same researchers observed that 88% of the captured gas can be desorbed and during the material regeneration 98% of the original weight is gained. This is another important property of LDH materials in high temperature CO2 separation applications as described later..

As mentioned, the thermal evolution of the layered structure has a great influence on the CO2 capture. The loss of superficial interlayer water occurs at 200 C. Then at temperatures between 300 and 400 C the layer decomposition begins, resulting in an amorphous 3D network with the highest surface area [30], so the adsorption temperature improves the CO2 capture in the order of 400 > 300 > 20 >200 C [41-42, 47, 52]

Several researchers have investigated a set of different factors to improve the CO2 sorption capacity. Yong et al. [47, 48] studied the factors which influence the CO2 capture in LDH materials, such as aluminum content, water content and heat treatment temperature. Regarding the M/Al-CO3 LDHs (M = Mg, Ni, Co, Cu or Zn), the best CO2 sorption capacity was obtained for the Mg/Al materials degassed at 400 C and with adsorption conditions of 25 C. In general, the sorption capacity follows the trend Ni > Mg > Co > Cu = Zn. However, when the degassed temperature is increased, the trend is modified to Mg (400 C) > Co (300C) > Ni (350C) > Cu (300C) >Zn (200C). These results show that Mg/Al-CO3 is the best composition at the degassing temperature of 400 C [47]. At this temperature, the material consists of an amorphous phase with optimal properties for use as CO2 captor [42]. Also, the influence of Al+3 has been studied as a trivalent cation at 25 and 300 C adsorption temperatures, by Yong [41] and Yamamoto [49] respectively. Both samples were degassed at 300 C and the results showed that the CO2 capture is influenced by the adsorption temperature. At a temperature of 25 C, the maximum adsorption was 0.41 mmol/g with an Mg/Al ratio equal to 1.5 (x = 0.375) [41] and at 300 C the amount of CO2 adsorbed was 1.5 mmol/g for a cation ratio of 1.66 (x = 0.4) [49]. The differences between the two capacities can be attributed to the Al content differences. The Al incorporation in the structure has two functions: 1) to increase the charge density on the brucite-like sheet; and 2) to reduce the interlaminar distance and the number of sites with high resistance to CO2 adsorption [48].

On the other hand, Qian et al. [50] studied the effect of the charge compensation anions (A- = CO3-2, NO3-1, Cl-, SO4-2 and HCO3-1) on the structural properties and CO2 adsorption capacity of Mg/Al-A- (molar ratio equal to 3). Despite all of the prepared LDH materials showed the typical XRD patterns of LDH materials, slight structural and microstructural differences were observed. In fact, the interlayer distance changed by varying the interlayer anions due to their difference in sizes and carried charges. These differences affect the morphology and the BET surface area of both fresh and heat-treated LDH materials. Additionally, thermal treatments were performed in order to optimize the adsorption capacity of these materials. The optimal temperature treatment was established for each Mg/Al-A- based on the surface area of each calcined LDH. Then the CO2 adsorption capacities of calcined LDH were tested at 200 C. Mg3/Al1CO3 showed the highest CO2 adsorption capacity (0.53 mmol/g). This value was much higher than those obtained for calcined Mg3/Al1-NO3 > Mg3/Al1-HCO3, Mg3Al1-Cl, and Mg3/Al1-SO4 ( 0.1 mmol/g). The results indicated that BET surface area of calcined LDHs seems be the main parameter that determines the CO2 adsorption capacity because the Mg-O active basic site [43, 45].

It has been demonstrated that the quasi-amorphous phase obtained by the thermal treatment of LDH at the lowest possible temperature has the highest CO2 capture capacity. This finding is in line with the fact that high calcination temperature can decrease the number of active MgO sites due to the formation of crystal MgO [51].

Yong [41] and Yamamoto [49] investigated the influence of the several types of anions. The results suggested that the amounts CO2 capture decrease as a function of the anion size, which promotes a larger interlayer spacing and the higher charge: Fe(CN)64-(1.5 mmol/g) > CO32- (0.5 mmol/g) > NO3- (0.4 mmol/g) > OH- (0.4-0.25 mmol/g). The reason is that Fe(CN)64- and CO32-, because they have more void space in the interlayer due size, and are able to accommodate higher CO2 quantities. Calcined layered double hydroxide derivatives have shown great potential for high temperature CO2 separation from flue gases. However, the presence of SOx and H2O from flue gases can strongly affect CO2 adsorption capacity and regeneration of hydrotalcite-like compounds. Flue gases emitted from power stations contain considerable amounts of water in the form of steam. The percentage of water found in the flue gas emitted from different sources varies between 7 and 22%, with the emissions from brown coal combustion having the highest water content [45]. For many other gas adsorption sorbents, steam generally has a negative effect on the adsorption performance because of competition for basic sites between CO2 and H2O. However, the presence of water or steam seems to be favorable for the adsorption capacity onto LDH [31,43,53,54]. This fact is the result of the increasing potential energy that is able to further activate basic sites, possibly by maintaining the hydroxyl concentration of the surface material and/or preventing site poisoning through carbonate or coke deposition [31]. An example of the above was reported by Yong et al. [47], who found that water or steam can increase the adsorption capacity of CO2 by about 25%, from 0.4 mmol/g to 0.5 mmol/g.

Ding et al. [31] studied CO2 adsorption at higher temperatures (480 C) under conditions for steam reforming of methane. They found an adsorption capacity of 0.58 mmol/g, which was independent of water vapor content in the feed. In turn, Reddy et al. [45] investigated calcined LDHs sorption performance influenced by CO2 wet-gas streams. LDH samples were calcined at 400 C [43] before measuring CO2 sorption at 200 C. The gas streams used were CO2, CO2 + H2O, flue gas (14% CO2, 4% O2 and 82 % N2) +12% H2O.

For a pure CO2 dry sorption, the maximum weight gain was 2.72% (~0.61 mmol/g) after 60 min, whereas the wet adsorption increased the weight of the calcined LDHs to 4.81%, showing an additional 2.09%, where He and He + H2O were used to remove the H2O water capture. The results showed that the helium has virtually no significant sorption affinity for the material, whereas the water-sorption profile of it clearly indicates a water weight gain of 1.67%, i.e., the gain was 0.1mmol/g due to steam presence, showing that water has a positive effect, shifting the CO2 sorption by 0.42% as compared to dry CO2 sorption. Also, these results revealed that in all cases about 70% sorption occurs during the first 5 min and reaches equilibrium after around 30 min.

To determine the influence of CO2, Reddy et al. [43] tested a sample in both, wet and dry CO2 stream conditions. The experiments showed that the same quantity of CO2 can be trapped for the solid sorbent after two hours. The presence of water in the stream only affects the kinetics of the process. This result is in agreement with that reported by Ding et al. [31]. On the other hand, the results of the material tested suggest that the fact the CO2 capture from flue gas was higher than in a pure stream of CO2 might have been because the polluted gas was diluted in the stream. The presence of the water does not enhance de CO2 capture; the maximum CO2 adsorbed was 0.9 mmol/g. The differences between Reddy et al. results and the previously mentioned studies can be caused by the use of uncalcined LDHs, which already contain an -OH network.

To apply these materials in industrial processes, it is important to know the times during which each sorbent material can be used. Tests of the cyclability in LDH materials disclose that as function of the temperature the CO2 capture time can vary. This can be attributed to CO2 chemisorbed during each cycle [54] and/or to the formation of spinel-based aluminas, such as -Al2O3 (at temperatures higher than 400 C). Hibino et al. [52] found that the carbonate content, acting as charge-compensating anion, continuously decreases in subsequent calcination rehydration cycles. Reddy et al. tested LDH materials during six CO2 adsorption (200 C)-desorption (300 C) cycles. The average amount gained was 0.58 mmol/g, whereas 75% of this value is desorbed, reaching desorption equilibrium after the third cycle. This can be attributed to the stabilization of the material phase and basic sites during the temperature swing.

Hufton et al. [54] studied a LDH material during several cycles in dry and wet CO2 flows. As previously discussed, the presence of steam in the flow gas improves the CO2 adsorption. However, after 10 adsorption cycles, the capture decreased 45%. The same behavior was observed in the dry gas flow. However, the final capture was similar to the wet gas stream, in agreement with Reddy et al. [43].

Recent studies have demonstrated that K-impregnated LDH or K-impregnated mixed oxides have a better CO2 capture capacity due to the addition of K alkaline-earth element that improves the chemical affinity between the acidic CO2 and alkaline surface of the sorbent material [32, 36, 55-56]. Additionally, it has been proposed that K-impregnation reduces the CO2 diffusion resistance in the material. [57]. Hufton et al. [58] showed that the K-impregnation increases the CO2 capture, but there is an optimal quantity of K to reach the maximum capture. Qiang et al. [50] tested an Mg3/Al1-CO3 (pH = 10) impregnated with 20 wt.% K2CO3. The CO2 adsorption capacity was increased between 0.81 and 0.85 mmol/g in the temperature range of 300 - 350 C. This adsorption capacity is adequate for application in water gas shift reactions (WGS).

Lee et al. [59] tested the behavior of three commercial LDHs impregnated with K (K2CO3/LDH ratio between 0 and 1). Three Mg/Al-CO3 LDH with different contents of magnesium were used. Results indicated that the sorption capacity of the LDH is improved by about 10 times with the optimal K2CO3 additions. Additionally, it was observed that impregnation is not the only factor that influences the adsorption but the composition too. The best value was obtained when the content of divalent cation was reduced and therefore, the material had a composition with the maximum trivalent cation content. The CO2 adsorption capacity improved from 0.1mmol/g to 0.95mmol/g with K2CO3/LDH weight ratio equal to 0.35 at 400 C. After determining the optimal alkaline source/LDH ratio, a set of samples was evaluated as a function of the temperature and the results showed a maximum of 1.35 mmol/g, at 50 C. In the impregnated materials, CO2 chemisorption can occur and the sorbed CO2 can be further stored as metal carbonate forms.

Other alkaline elements can be used to improve the sorption capacity of materials. Martunus et al. [46] studied the impregnation of LDH with Na and K. The LDH samples were thermally treated at 450 C for 5 min then calcined samples were re-crystallized in K2CO3 and Na2CO3 (1 M) solutions. The re-crystallized materials were tested as CO2 captors and the capture was maximum with LDH-Na (0.688 mmol/g) > LDH- K (0.575 mmol/g) at 350 C after five cycles. Finally, the re-crystallized material with the highest capture was calcined at 650 C for 4 h and re-crystallized with a solution containing the appropriate quantities of K and Na to achieve alkaline metal loading up to 20%. When the sample was Impregnated with additional K and Na at 18.4% and 1.6%, respectively, the adsorption capacity rose from 0.688 to 1.21 mmol/g. This capacity increase was achievable despite the relatively low BET surface area, equal to 124 m2/g.

Other alkaline elements such as cesium have been studied as reinforcement. Oliveira et al. [55] tested commercial Mg1/Al1-CO3 and Mg6Al1-CO3 impregnated with K and Cs carbonates. The materials were evaluated in the presence of steam (26% v/v water content) gas at different temperatures (306, 403 and 510 C) at 0.4 bar of CO2 partial pressure (total pressure 2 bar). The LDH with the highest sorption capacity was Mg1/Al1-CO3K with 0.76 mmol/g at 403 C. Among the Cs impregnated samples, the Mg6Al1-CO3-Cs presented the highest capacity with 0.41 mmol/g, while the commercial LDH samples presented CO2 sorption capacities around 0.1 mmol/g.

The results suggest the existence of a sorption mechanism combining physical adsorption and chemical reaction. First the maximum physical adsorption is reached, then the chemisorption begins, but there is an optimal temperature. If the temperature is too low, the chemisorption does not happen, but with higher temperatures the loss of porosity impedes the contact of CO2 molecules with active basic sites promoted by the alkaline element addition.

These results suggest there is an optimum amount of K2CO3 to impregnate the LDH that achieves a balance between the increase in the basicity of the sorbent material and its reduction of surface area, associated with CO2 capture capacity. The influence of potassium is currently not clear and the relevant research is still ongoing. Finally, CO2 adsorption capacity on the synthesized 20 wt.%K2CO3/Mg3/Al1CO3 (pH = 10) probably could be further increased in the presence of steam.

Membrane-based processes, related to gas separation and purification, have achieved an important level of development for a variety of industrial applications [60]. Therefore, the use of separation membranes is one of the promising technologies for reducing the emissions of greenhouse gases such as CO2. The term membrane is defined as a permselective barrier between two phases, the feed or upstream and permeate or downstream side [61]. This permselective barrier has the property to control the rate of transport of different species from the upstream to the downstream side, causing the concentration or purification of one of the species present in the feed gas mixture.

Membrane-based processes offer the advantage of large scale application to separate CO2 from a gas mixture. Figure 2 schematizes the process where concentrated CO2 is selectively separated from flue gas that is mainly composed of nitrogen and carbon dioxide along with other gases such as water vapor, SOx, NOx and methane. Subsequent to the membrane process, concentrated CO2 obtained at the permeate side can be disposed or used as raw material for the synthesis of several chemicals such as fuel and value-added products [62].

Membrane-based processes for the carbon dioxide separation from flue gases. The concentrated CO2 is obtained in the permeate side.

Of course, the rate of transport or permeation properties of a particular gas through a given membrane depend on the nature of the permeant gas, as well as the physical and chemical properties of the membrane.

Inorganic membranes are more thermally and chemically stable and have better mechanical properties than organic polymer membranes; ceramic membranes offer both the advantage of large scale application and potential for pre- and post-combustion CO2 separation applications, where membranes systems would be operating at elevated temperatures of 300-1000 C [63].

Inorganic ceramic membranes can be classified as porous and nonporous or dense. These differ from each other not only in their structures but also in the mechanism of permeation. In porous membranes, the transport of species is explained with the pore-flow model, in which permeants are transported by pressure-driven convective flow through the pore network. Separation occurs because one of the permeants is excluded (molecular filtration or sieving) from the pores in the membrane and remains in the retentate while the other permeants move towards the downstream side. On the other hand, in nonporous membranes, separation occurs by solution-diffusion, in which permeants dissolve in the membrane material and then diffuse through the bulk membrane by a concentration gradient [60].

Among the porous systems for CO2 separation, both microporous (carbon, silica and zeolite membranes) and modified mesoporous membranes have been reported [63-64].

Zeolites are hydrous crystalline aluminosilicates that exhibit an intracrystalline microporous structure as a result of the particular three-dimensional arrangement of their TO4 tetrahedral units (T=Si or Al) [65]. Zeolite membranes are commonly prepared as thin films grown on porous alumina supports via hydrothermal synthesis and dry gel conversion methods [66]. Zeolite membranes of different structures have been developed to separate CO2 from other gases via molecular sieving [67-69]. For example, membranes prepared with the 12-member ring faujasite (FAU)-type zeolite show high separation factors of 20-100 for binary gas mixtures of CO2/N2 [69]. In the same sense, T zeolite membranes exhibited very high selectivity, of about 400, for CO2/CH4 and 104 for CO2/N2. The high selectivity of CO2/CH4 exhibited by T zeolites is due to the small pore size of about 0.41 nm, which is similar in size to the CH4 molecule but larger than CO2 [69]. Table 1 shows the kinetic diameter of various molecules that are present in CO2 containing gas mixtures such as flue and natural gas [70].

Kinetic diameter of various molecules based on the Lennard Jhones relationship.

Deca-dodecasil 3R (DDR) (0.36 nm x 0.44 nm), and pseudo-zeolite materials like silicoaluminophosphate (SAPO)-34 (0.38 nm) also show high CO2/CH4 selectivities due to narrow molecular sieving, which controls molecular transport into this material [69, 71-73]. For example, Tomita et al. [74] obtained a CO2/CH4 separation factor of 220 and CO2 permeance values of 7 x 10-8 mol m-2 s-1 Pa-1 at 28 C on a DDR membrane [75].

As discussed, one of the most important factors controlling permeation through microporous membranes is the restriction imposed by the molecular size of the permeant. However, the transport mechanism in microporous systems is more complex than just size exclusion and the permeation and selectivity properties are also affected by competitive adsorption among perment species that produce differences in mobility [76].

Thus, the diffusion mechanism for gas permeation through microporous membranes can be characterized by two modes: one controlled by adsorption and a second one where diffusion dominates [63]. In the case of adsorption-controlled mode with permeating gases having strong affinity with the membrane, a gas permeation flux equation is obtained by assuming steady-state single gas permeation, a constant diffusivity and a single gas adsorption described by a Langmuir-type adsorption isotherm, as in Eq. (5).

J=qsDcL1+bPf1+bPporJ=qsDcL1-p1+fE5

where J is the permeation flux, is a geometric correction factor that involves both membrane porosity and tortuosity, Dc is the corrected diffusivity of the permeating species, L is the membrane thickness, Pf and Pp represent the feed and permeate pressure respectively and f and p represent the relative occupancies.

Furthermore, if the adsorption isotherm of the permeating gas is linear (1 >> bP), then flux permeation is described by Eq. (6).

F=qsDcLDcLKE6

where F is the permeance and K = qsb is the adsorption equilibrium constant. Therefore, from Eq. (5) it can be concluded that permeance is determined by both diffusivity (Dc) and adsorption (K). Based on the above, an interesting option to enhance membrane properties is to intercalate zeolite membranes with alkaline and alkaline-earth cations. Zeolite intercalation can enhance the separation between CO2 and other molecules such as N2 by promoting preferential CO2 adsorption [63, 77]. It is well known that zeolites show affinity for polar molecules, like CO2, due to the strong interaction of their quadrupole moment with the electric field of the zeolite framework. In this sense, the adsorption properties of zeolites can be enhanced by the inclusion of exchangeable cations within the cavities of zeolites where the adsorbent-adsorbate interactions are influenced by the basicity and electric field of the adsorbent cavities [78-80]. Lara-Medina et al. [77] carried out separation studies of CO2 and N2 with a silicalite-1 zeolite membrane prepared via hydrothermal synthesis and subsequently modified by using lithium solutions in order to promote preferential CO2 adsorption and diffusion. CO2/N2 separation factor increases from 1.46 up to 6 at 25 psi and 400 C after lithium modification. An et al. [79] studied a series of membranes prepared starting from natural Clinoptilolite zeolite rocks. Disk membranes were obtained by cutting and polishing of the original minerals, which were subsequently chemically treated with aqueous solutions containing Li, Na, Sr or Ba ions. Ionic exchanged membranes showed better permeation properties due to the presence of the extra framework cations.

Although zeolite membranes offer certain advantages in comparison with polymer membranes, such as chemical stability, the main issues are related to the selectivity decrease as a function of the permeation temperature. This is explained in terms of the contribution of the adsorption to the separation, which decreases sharply as temperature increases. At high temperature, physical adsorption becomes negligible and permeation is mainly controlled by diffusion [63, 76]. Additionally, due to the fact that CO2 and N2 molecules have similar sizes (Table 1), the difference in diffusivity is not a strong controlling factor in determining selectivity.

Modified -Al2O3 mesoporous membranes have been also reported as a means for CO2 separation [64]. Transport mechanisms in porous membranes have the contribution of different regimes. An overview of the different mechanisms is given in Table 2.

Transport mechanisms in porous membranes.

Depending on the particular system, permeability of a membrane can involve several transport mechanisms that take place simultaneously. Considering no membrane defects and pore sizes in the range of 2.5-5 nm, -Al2O3 based membranes theoretically have two transport regimes: Knudsen diffusion and surface diffusion. Eq. (7) describes the permeability of a membrane by taking into consideration the Knudsen and surface diffusion.

F=2r3RTL8RTM0.5+2DsrA0NavdxsdPE7

where r is the mean pore radius, is a shape factor, R is the universal gas constant, T is the temperature, P is the mean pressure, M is molar mass of the gas, Ao is the surface area occupied by a molecule, Ds is the surface diffusion coefficient, Nav is Avogadro's constant and Xs is the percentage of occupied surface compared with a monolayer [81].

For the cases when Knudsen diffusion dominates, selectivity can be correlated to the molecular weights of the permeating gases by the so called Grahams law of diffusion, which establishes that the transport rate of any gas is inversely proportional to the square root of its molecular weight. The CO2/N2 separation factor considering pure Knudsen diffusion is given by Eq. (8) and has a value of just 0.8. Therefore, Eq. (8) clearly shows that separation via Knudsen is limited for systems where species are of similar molecular weight.

See the original post here:
Biochemistry | IntechOpen

How to Become a Biochemist | EnvironmentalScience.org

Biochemistry is the study of living things at the molecular level, focusing mainly on the processes that occur. For example, they may study cell development, how cell structure relates to function, how cells communicate with each other to fight disease or regulate an organism's development, and how they metabolize food and oxygen.

Many biochemists study how pharmaceutical drugs and foods affect an organism's biology. Some also study how environmental toxins are metabolized, and how they may disrupt biological processes.

Because biochemistry encompasses all living things, it's a very wide field of study with a range of applications in medicine, agriculture, and the environment.

Learn more about biochemistry degrees.

Biochemists may study cellular and molecular processes to increase our general understanding about them, or work on solving specific problems. For example, they may try to figure out how a chemical like Bisphenol A (BPA), found in some plastics, affects the human body. Others may try to discover how certain genes or environmental factors cause disease, and how to suppress or "turn off" the errant mechanism. Those working in agriculture research ways to genetically modify crops for resilience to drought or pests. Some work on developing biofuels.

Regardless of the field of application, most biochemists perform many of the same duties. They plan and conduct experiments to isolate, quantify and analyze hormones, enzymes, and toxins, and to determine the effects of substances like drugs, food and toxins on biological processes. They may also develop new analytical techniques to detect pollutants and their metabolites, or to study biological processes. They may also use computer software to determine the three-dimensional structure of molecules, or use math to describe the chemical relationships between substances found in the environment and in the body. They also share research findings by writing reports, recommendations, or scientific articles, or by presenting at scientific conferences.

This field clearly plays an important role in public health. Biochemists helps determine the environmental causes of disease - information that can help policymakers eliminate or reduce risk, and potentially help doctors treat the conditions. But biochemistry is vital to many aspects of sustainability as well.

For example, these scientists may study the toxicological effects of industrial chemicals and other pollutants on wildlife. Some discover new ways to use the biological processes of plants and microbes to break down these pollutants. Some are working on solving the food crisis by developing inexpensive, high-yield, nutritious, and sustainable crops. Others study ways to turn the energy in waste products, crops, and algae into biofuels. Some biochemists are trying to develop artificial photosynthesis, a process intended to mimic the way plants derive energy from the sun, to develop solar fuel.

Biochemists work for a variety of industries and government agencies. For example, they may analyze the effects of air, water, and soil pollution on people, wildlife, plants, and crops for the U.S. Environmental Protection Agency or Department of Agriculture. They may also study the effects of drugs or food for the National Institutes of Health or the Food and Drug Administration. Many biochemists are employed by pharmaceutical firms and companies dealing with food-related chemicals such as animal feed, agricultural chemicals, and food for human consumption, where they conduct research to understand disease and develop new products. Some work in manufacturing, energy development, or environmental restoration firms. Others work in hospital laboratories. They may also work as faculty, research staff, or teachers at colleges, universities, and secondary schools. Some also work for law firms, where they deal with scientific cases.

Most biochemists work indoors in laboratories and offices. Some, especially those working for environmental restoration firms, may travel to outdoor work sites. Lab and field work may result in exposure to biological or chemical hazards. Following established safety procedures is important in these situations.

Most biochemists work full time, and many work more than 40 hours per week. Employers, industries, and work environments can vary by the type of biochemistry practiced.

The U.S. Bureau of Labor Statistics (BLS) gives the 2012 average annual salary for biochemists and biophysicists as $84,320. However, The Scientist's more recent Life Sciences Salary Survey lists the average 2014 salary for biochemists as $100,433.

Table data taken from BLS (http://www.bls.gov/oes/current/oes191021.htm)

Employment in this field is expected to grow 19% from 2012 to 2022, which is faster than the average for all occupations. However, since it's a small field to begin with, only about 5,400 new jobs will be created. Due to an aging population, much of the growth will be in medical research. However, increased pressure on food and energy resources will drive growth in agricultural and biofuels research. Concerns about pollution will also expand opportunities for biochemists who work on toxicological effects and bioremediation.

Much of the research in biochemistry and biophysics, particularly at colleges and universities, is dependent on funding from the federal government. Federal budgets and the availability of research funding may affect the job market from year to year.

Senior tier biochemist jobs may have the following elements in addition to tier-one responsibilities:

Some universities offer a one-year post-graduate training program in laboratory techniques, which is highly valued by many private companies. Some let you work towards a bachelor's degree and a microbiology-related certificate at the same time.

While those with bachelor's degrees may qualify for some entry-level positions, most biochemists earn advanced degrees. Graduate study usually involves a lot of laboratory work, and allows you to specialize in a particular area like molecular biology or bioinformatics. Graduate students earn degrees (M.S. or M.A.) in Biochemistry, Biochemistry and Molecular Biology, Biochemical Engineering, Biological Sciences, Biomedical Sciences, or other related areas.

However, doctoral degrees are required for positions involving independent research and development. Ph.D. programs generally include more advanced coursework on biochemistry, as well as independent research. Most newly minted PhDs start out in postdoctoral research positions. These positions can lead to publication, which is crucial to landing a permanent research position. Many biochemists bide their time in multiple postdoctoral positions before getting a permanent academic appointment.

Original post:
How to Become a Biochemist | EnvironmentalScience.org

ICMR VCRC Recruitment 2019 for Project Technical Officer and other Posts, Interview on November 09 – Jagran Josh

Indian Council of Medical Research Vector Control Research Centre (ICMR VCRC) has notified for Project Technical Officer and Project Technician Posts. The eligible candidates can appear in the walk-in-interview scheduled on 09 November 2019.

ICMR VCRC Recruitment 2019 for Project Technical Officer

ICMR VCRC Jobs Notification: Indian Council of Medical Research Vector Control Research Centre (ICMR VCRC) has invited applications for Project Technical Officer and Project Technician Posts. The eligible candidates can appear in the walk-in-interview scheduled on 09 November 2019.

Candidates with certain education qualification can apply for Indian Council of Medical Research VCRC Jobs Notification. Selection for the posts will be based on the performance in written test/interview.

Notification Details for Indian Council of Medical Research VCRC Jobs Notification:Advertisement No: 18/Project/2019, Date 23 October 2019

Important Dates for Indian Council of Medical Research VCRC Jobs Notification:Date of Walk-in-Interview: 09 November 2019

Also Read

JPSC Recruitment 2019 for 637 Assistant Engineer Posts, Check Official Notification Here

Vacancy Details for Indian Council of Medical Research VCRC Jobs Notification:Project Technical Officer-01Project Technician-01

Eligibility Criteria for Indian Council of Medical Research VCRC Jobs Notification:Educational QualificationProject Technical Officer-Candidate should have Graduate in Life Sciences from a recognized University with five years' work experience from a recognized institution or University in the field of Molecular Biology/Biotechnology/Biochemistry/Molecular diagnostics of vector borne diseases or Master degree in Molecular Biology/Biotechnology/Biochemistry/Genomics. Project Technician-Candidates should have High School or equivalent with one year experience in laboratory technology/entomology from a Government recognized Institute or recognized boardCandidates should have Intermediate with science subjects shall be treated as equivalent to 2 years experience.For details of the educational qualification of the posts, you can check the notification link.Monthly Consolidated Salary for Indian Council of Medical Research VCRC Jobs Notification:Project Technical Officer-Rs. 32,000 Project Technician-Rs. 16,000

Age Limit for Indian Council of Medical Research VCRC Jobs Notification:Project Technical Officer-Not exceeding 30 YearsProject Technician-Not exceeding 25 Years

You May Also Read

Jesus & Mary College Recruitment 2019 for 29 Assistant Professor Posts

SAIL, Bhilai Recruitment 2019 for 296 Operators cum Technician and other Posts, Check Details Here

NSRTC Recruitment 2019 for Research Associate & Other Posts

How to Apply for Indian Council of Medical Research VCRC Jobs Notification:The eligible candidates can download the application form from the website http://www.vcrc.res.in and attend the written test/interview with all the original documents, Aadhar card along with one set of xerox of the same duly self-attested and a recent passport size photograph for attending the written test/interview.

Read more here:
ICMR VCRC Recruitment 2019 for Project Technical Officer and other Posts, Interview on November 09 - Jagran Josh

Career counselling: questions and answers | Lahore | thenews.com.pk – The News International

Q1). I am a student of MBBS second year. I want to know what should I do after MBBS? I want to do CSS after it. Will it be right? Will it be possible to continue both fields? Please tell me the future of both fields in detail. (Sehrish Iqbal Islamabad)

Ans: Since you are a 2nd year MBBS student, I would like you to concentrate on your studies and first complete your MBBS and get yourself register as a doctor. Following this if you wish to join the civil service or come into public sector job you can look at doing a CSS exam. If you wish to go abroad for further studies whether to America or UK you should decide once you are a qualified doctor. My suggestion at this stage is to work hard and pass all your professional examination so that you have a full MBBS degree to make you eligible for applying for a CSS exam.

Q2). Sir, I am doing BS Biochemistry and I have decided to do my research work in Clinical Biochemistry. I wanted to ask what career prospects I can have with this kind of research. Also, then in what field should I choose for MPhil? (Zehra Mumtaz Islamabad)

Ans: Biochemistry is a very strong and emerging subject area with huge opportunities for research. It is important for you to decide whether you want to do your MPhil from Pakistan or abroad? In Pakistan you will need to search some good universities and look at the Department of Biochemistry before you choose the final university. There are many areas that you can continue your research either at MPhil level or PhD level. Some of these areas could include Endocrinology and Metabolism, Core Bio analysis and Toxicology, Core Developmental Biochemistry.

Q3). I want to do MS in Pathology as this area is quite in demand. My CGPA is undergraduate degree is 3.60. Please let me know what is the scope of Pathology? (Zahid Munnawar Hyderabad)

Ans: Pathology is a very in-demand subject area, however, you will have to be careful in choosing the right specialization with a combination of the subjects that include Molecular Biology, Micro Biology, Bio Chemistry and Clinical Bio Chemistry when choosing your post graduate course. There are quite a few universities that offer courses leading to the above you may also find many scholarships abroad in these areas.

Q1). My son has completed BBA (honor) Finance and ACCA. Do you advise to do MBA (Finance) or something else? (Rafi Fazal - Lahore)

Ans: The first thing your son should do is to gain some experience whether through paid employment or an unpaid internship to get real time experience. My suggestion would be to look at pick chartered accountants or companies engaged in making financial feasibilities and budgets that also involves risk assessment and evaluation. Having worked for a few years in the commerce he can then look towards doing an MBA.

(Syed Azhar Husnain Abidi is a renowned educationist in Pakistan, with more than 20 years of experience as provider of education counselling services. He has represented Pakistan in over 100 national and international seminars, conferences and fora. He is a recipient of the most coveted civil award Tamgha-e-Imtiaz).

Go here to read the rest:
Career counselling: questions and answers | Lahore | thenews.com.pk - The News International

Mystery science – Gazette

Students from local high schools descended on the Department of Biochemistry recently to try out their scientific and detective skills.

For the first time, the department opened its doors to students from ODonel and Holy Heart for a daylong field trip. It saw them role play as junior crime scene investigation agents tasked with determining if a local fisherman had a freezer full of flounder or near extinct Atlantic Bluefin tuna.

Using a procedure called the Biuret method, students compared the composition of both fish species by measuring protein content.

Our equipment is basically gathering dust over the summer, so this was an opportunity to introduce high school students to biochemistry, let them see the lab and apply some modern techniques to the things theyve been learning in class, said Dr. Mark Berry, head, Department of Biochemistry.

Jamie Parsons is a science teacher at Holy Heart and an alumnus of the biochemistry department; he participated in the field trip with students from his Grade 11 international baccalaureate (IB) biology class.

He says he speaks really highlyof the biochemistry program at Memorial.

This allows my students to get a glimpse of the kind of fun stuff they can learn about and hopefully it will plant the seed that will get them to come to Memorial, said Mr. Parsons. They think away is better, but Ive been telling them Memorial is a great school. Theres a natural tendency to want to go and explore, and I get that. But its also okay to stay here. Many of us who stay here also do well.

Photo: Chris Hammond

Mr. Parsons also says that he and the students cant do everything theyd like to in their labs and that this was a chance to expose some of Holy Hearts top students to Memorial and the biochemistry department in particular.

Dr. Berry is hoping to repeat the field trip in future years with other schools.

Im in preliminary discussions with the biology and chemistry departments to see if we can put together a Natural Sciences and Engineering Research Council of Canada Promo Science proposal, he said. Id love to see this expand to a week or two of visits from other school groups, both high school and junior high.

The program was funded by Memorials Quick Start Fund for Public Engagement. It supports small projects that support activities that foster public engagement and collaboration.

Kelly Foss is a communications advisor with the Faculty of Science. She can be reached at kfoss@mun.ca.

Continued here:
Mystery science - Gazette

Biochemistry, B.S. < Temple University

The Bachelor of Science degree in Biochemistry prepares students for excellence in graduate or medical school, and employment in the chemical, biotechnological, or pharmaceutical industries. Students learn a wide array of topics in Biology, Chemistry, Mathematics, and Physics. In upper division studies, Biochemistry majors learn to apply biochemical principles to real-life situations via problem-based approaches in their courses. Laboratory courses give students the tools they will need as biochemists to pursue research. Accomplished majors are encouraged to pursue independent research with a professor, and to present their work internally and at national meetings.

Undergraduate Contact Information:

Dr. Robert Sanders, ChairBiology-Life Sciences Building, Room 255215-204-8851

Dr. Dan Strongin, Chemistry ChairBeury Hall, Room 130215-204-7118

Dr. Angela Bricker, Faculty Advisor, BiologyBiology-Life Sciences Building, Room 248C215-204-8578abricker@temple.edu

Dr. Spiridoula Matsika, Faculty Advisor (Last names A-G), ChemistryBeury Hall, Room 242215-204-7703spiridoula.matsika@temple.edu

Dr. Vince Voelz, Faculty Advisor (Last names H-N), ChemistryBeury Hall, Room 240215-204-1973vincent.voelz@temple.edu

Dr. Michael Zdilla, Faculty Advisor (Last names O-Z), ChemistryChemistry DepartmentBeury Hall, Room 440215-204-7886michael.zdilla@temple.edu

Note: A grade of C or higher in CHEM1031 or its Honors alternate is required to take BIOL1111. Grades of C or higher in both CHEM1031 and CHEM1032 or their Honors alternates are required to take BIOL2112. Grades of C or higher in BIOL1111 and BIOL2112 or their Honors alternates are required to take upper-level Biology courses, and a C- or higher is required unless otherwise specified in all other courses for the major, including course prerequisites. Most research and Independent Study courses are not available for major credit, such as:

Courses listed under the major requirements for the degree will be included in the calculation of the major GPA. Courses that could not apply toward the major as an elective or required course would not be counted in the calculation of the major GPA. This would include BIOL1011, for example.

To graduate with Distinction in Major, students are required to achieve a 3.33 GPA or higher in all the Biology and Chemistry courses in their major.

All prospective majors should schedule an appointment with one of the departmental advisors (names of current Faculty Advisors are available in the About section) to plan a program of study. The recommended order of courses for the major is listed below; a different order is acceptable as long as the student adheres to prerequisite requirements.

Students are required to take two advanced biochemistry electives from the following list:

Notes:

Here is the original post:
Biochemistry, B.S. < Temple University

Meet Ghanaian scientist Professor Awandare helping us understand the coronavirus – GhanaWeb

General News of Monday, 13 April 2020

Source: mynewsgh.com

Professor Gordon Akanzuwine Awandare

One of the leading Ghanaian scientists helping us understand the novel coronavirus disease is Professor Gordon Akanzuwine Awandare of the School of Biochemistry and the West African Centre for Cell Biology of Infectious Pathogens (WACCBIP) at the University of Ghana.

He, together with other leading scientists at the University of Ghana, has successfully sequenced the genome of the novel coronavirus disease by examining some 15 confirmed cases of the disease in the country.

Prof Awandare has been a leading light in research on many diseases in the country, especially the malaria parasite.

Born in Kandiga in the Kassena Nankana West District of the Upper East Region, Prof Awandare battled with recurring malaria as a child.

Defying all odds to have a good education, he obtained an a Bsc in Biochemistry from the University of Ghana in 1998 and an MSc in the same field in 2002 before obtaining his PhD in the area in 2007 from the University of Pittsburgh in the United States of America. His area of interest was the malaria parasite, inspired partly by his battle with the disease as a child.

Driven by patriotism, he returned to Ghana after spending three years in America contributing to knowledge there.

Prof Awandare took extraordinary steps to set up his own research group notwithstanding the lack of funds and other bottlenecks.

His major breakthrough came in 2013 when he led a consortium that secured funds to set up a new state of the art centre in the country to research into infectious pathogens. The consortium secured some $8 million from the World Bank, and Prof Awandare became the founding director of the West African Centre for Cell Biology of Infectious Pathogens (WACCBIP) in 2013.

The Centre cutting edge research has ensured that it has secured several other funding to undertake research into many diseases.

He has received many awards for his excellence on research.

Send your news stories to and via WhatsApp on +233 55 2699 625.

Visit link:
Meet Ghanaian scientist Professor Awandare helping us understand the coronavirus - GhanaWeb

Biochemistry & Biophysics – University of Rochester Medical …

URMC / Biochemistry & Biophysics

The Department of Biochemistry & Biophysics (B&B) strives to understand the molecular mechanisms of important biological processes, thereby providing insight into how disruption of these mechanisms causes disease. Departmental research is generously supported by the National Institutes of Health (NIH). NIH instrument funds have contributed to our recent two million dollar investment in cutting edge structural biology, biophysical and mass spectrometry-based equipment. Furthermore, income generated from intellectual property derived from departmental research discoveries continues to be reinvested back into the department, and used to stimulate the genesis of private biotechnology companies.

In addition to supporting our research, the NIH has recognized our excellence in the Biochemistry & Molecular Biology (BMB) and Biophysics, Structural & Computational Biology (BSCB) Ph.D. programs by awarding the university a highly competitive interdepartmental T32 graduate training grant. Our commitment to graduate education is apparent from the positions acquired by our previous students and fellows, who are professors at major research universities and leaders in corporate research. Our continued focus on pioneering research and quality education ensures our position as a premier Biochemistry & Biophysics department.

Jeffrey J. Hayes , Ph.D. Chair, Department of Biochemistry & Biophysics

Unraveling the Role of RNA Structure in Gene Regulation Through Studies of the RNA Helicase Dbp2/DDX5

Elizabeth J. Tran, Ph.D. Associate Professor, Department of Biochemistry, Purdue University, West Lafayette, IN

Wed, Sep 27 - 2:00 PM MC K-307 (3-6408)

All Seminars

May 26, 2017 Study: A New Way to Slow Cancer Cell Growth

April 27, 2017 Using rooster testes to learn how the body fights viruses

April 1, 2017 BMB, BSCB Students Win 2017 Edward Peck Curtis Award for Excellence in Teaching by a Graduate Student

February 7, 2017 Maquat Receives Lifetime Achievement Award in Science from International RNA Society

December 12, 2016 Mitchell O'Connell Lab To Open

All news

Visit link:
Biochemistry & Biophysics - University of Rochester Medical ...

Global Itaconic Acid Market 2019 Scope of Current and Future Industry 2024 – Chronicle 99

The research report GlobalItaconic Acid Market Growth 2019-2024presents a unique tool for analyzing the market in terms of strengths and weakness, highlighting opportunities, and supporting strategic and skillful decision-making. The report discovers the newest industry data about the long-run prospects of this Itaconic Acid market, which can help industry contenders to understand the market flow throughout the period 2019-2024.

The report describes the market in detail in terms of the economic and regulatory factors that are currently shaping themarkets growth trajectory, the regional segmentation of the global market, and an analysis of the markets downstream and upstream value andsupply chains. Further, the industry structure together with the landscape, the problems along with business strategies and market effectiveness are covered in this report.

DOWNLOAD FREE SAMPLE REPORT:https://www.mrinsights.biz/report-detail/212512/request-sample

Key Findings By This Report:

The report also presents the market competitive landscape and a corresponding detailed analysis of the major vendor/manufacturers in the Itaconic Acid market. The reportprovides knowledge of the leading market players within the market. The key manufacturers covered in this report:Kehai Biochemistry, Guoguang Biochemistry, Alpha Chemika, Zhongshun Science & Technology, Huaming Biochemistry,

The report includes market division study over the significant geographies of the world such as North America (United States, Canada and Mexico), Europe (Germany, France, UK, Russia and Italy), Asia-Pacific (China, Japan, Korea, India and Southeast Asia), South America (Brazil, Argentina, Colombia etc.), Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa).

Moreover, in this report, other aspects such as customer base, sales reach, local coverage, production price trends, and production cost layout are also analyzed. Profiles of competitors of the Itaconic Acid market as well as core competencies and investments in each segment and an innovative analysis of their current developments has been provided in this research study. The market reports provide all data with easily digestible information to guide every businessmans future innovation and move the business forward.

The Goals of This Report:

ACCESS FULL REPORT:https://www.mrinsights.biz/report/global-itaconic-acid-market-growth-2019-2024-212512.html

Moreover, the report packs product analysis, mergers, collaborations, and supply chains analysis. The research report offers market dimensions and evaluations for the period from 2019 to 2024. The complete value chain, as well as downstream and upstream essentials, are further investigated in this report. The market values presented in this report is based on data and information collected at a regional stage.

Customization of the Report:This report can be customized to meet the clients requirements. Please connect with our sales team (sales@mrinsights.biz), who will ensure that you get a report that suits your needs. You can also get in touch with our executives on +1-201-465-4211 to share your research requirements.

Read this article:
Global Itaconic Acid Market 2019 Scope of Current and Future Industry 2024 - Chronicle 99

UNE hands off more than 3200 teddy bears to United Way of York County – Mirage News

The University of New England handed off over 3,000 teddy bears and other stuffed animals to the United Way of York County on Friday, Feb. 28, in a ceremony commemorating the Universitys fourth annual Teddy Bear Toss.

The toss is organized by the student building managers of the Harold Alfond Forum (HAF) on the Universitys Biddeford Campus.

Each year, during both a mens and womens hockey game, fans throw teddy bears onto the ice when the Noreasters score their first goal. The bears collected in advance through community donations are then handed to the United Way, which further distributes them to community organizations across southern Maine.

This years Teddy Bear Toss, held on Jan. 31, collected a record 3,268 stuffed animals to go to children in the region. To date, UNE has donated 10,168 stuffed animals to the United Way.

The United Ways mission is to improve lives by mobilizing people and resources. That is the goal of the Teddy Bear Toss, said D.J. Whitten, manager of the HAF. We believe deeply that the planning of this event each year provides our student building managers an experience that complements their overall experience at UNE and gives them skills they can take with them their entire lives.

Marine biology student Conor Wiley (21) echoed Whittens sentiment. This was Wileys second time organizing the Teddy Bear Toss, and he said the collaborative and charitable nature of the event keeps him coming back.

Being a part of the Teddy Bear Toss and coming to this handoff last year really showed me that there is a bigger world out there and that there are people who would love to be in my position here, worrying about my biochemistry test instead of worrying about things that are much more serious, Wiley said.

During the ceremony, held at the forum, students and other attendees heard from nearly a dozen community partners about where the bears will go and whom they will benefit.

Kim LaChance, administration coordinator and volunteer manager for Southern Maine Health Care, spoke of the fear children experience when they are faced with a hospital visit and how the teddy bears can ease the suffering.

The most important thing that people have when they come to our hospital is care, and the care isnt just clinical care; the care is emotional care, LaChance told the crowd of about three dozen. When one of our staff members has the capability to go in a closet and get a stuffed animal for a person, it takes that fear away and gives a little piece of hope that changes the whole scope of their experience there.

Mike Ouellette, food pantry coordinator at York County Shelter Programs, also spoke about easing fear the fear and stigma families often face when they enter the pantry.

Sometimes it is hard to make that step into an organization like ours and admit that you need help, Ouellette said. I put all these bears into a room, and when I see a new family that comes in, I invite the child and parents to the room. As soon as that door opens up and they see all these bears, their eyes light up. That fear of being there seems to go away.

Barb Wentworth, president and chief executive officer of the United Way of York County, thanked UNE and the HAF student building managers for coordinating the toss and subsequent handoff.

This is such a win-win, Wentworth said. That bear or dog, cat, or whatever it might be is going to bring a smile to someones face. This is like a stone in a pond rippling out: you never know who these will touch.

UNE President James D. Herbert, Ph.D., welcomed the crowd. He spoke about the Universitys partnership with the United Way.

The partnership between the United Way is strong, and it is growing, he said. The Teddy Bear Toss is one of the most fun events for me every year, and this year was an especially poignant and special year.

Herberts comment referred to the fact that this years handoff included a donation of teddy bears and other stuffed animals from a memorial to basketball legend Kobe Bryant by officials at Lower Merion High School outside Philadelphia, which Bryant attended and whose gymnasium bears his name.

Bryant and his daughter, Gianna, were tragically killed along with seven others on Jan. 26, in a helicopter crash outside Los Angeles.

The high school is the same one Herbert and UNE First Lady Lynn Brandsmas three children attended. Brandsma, who also spoke at the event, said the bears were offered to UNE after she reached out to those she knew at the school to express her condolences.

While the bears were received after the actual Teddy Bear Toss, they were displayed in the lobby of the HAF, along with a letter written by Brandsma and cards for UNE students and visitors to write messages of support for those at the school.

Although I never met Kobe face to face, he was such a large part of Lower Merion High School that its hard to imagine that school without him, Brandsma said. I am very honored that a very small piece of Kobes legacy will be passed on to the United Way of York County and, most importantly, to the children of southern Maine.

Following the event, HAF student building managers distributed the bears to receiving agencies, including:

View coverage of the Teddy Bear Toss handoff event on WGME CBS 13. Also see stories from WGME and NEWS CENTER Maine about the Kobe Bryant memorial display.

Original post:
UNE hands off more than 3200 teddy bears to United Way of York County - Mirage News

Doctor of biochemistry worked at Loma Linda University – Redlands News

Dr. Ronald Henry Hillock of Las Vegas, who worked at Loma Linda University for 40 years as a clinical chemist and a professor of biochemistry, died with his family by his side on Feb. 2, 2020. He was 85.

Born on July 5, 1934, in Paris, Ontario, Canada, he lived in Loma Linda 41 years prior to moving to Las Vegas.

He was a U.S. Air Force veteran.

During his service, he became a clinical laboratory technician, leading to a distinguished career in academia and clinical medicine.

He is survived by his wife Thelma of 65 years; daughter Janet Hillock Barone of Longboat Key, Florida; son Ronald W. Hillock, M.D. of Las Vegas; daughter Dawn L. Hillock of Las Vegas; four grandchildren, Chris Johnson of Whittier, California, Andrea Barone of Hopkinton, Massachusetts, Michael Barone of Rocky Hill, Connecticut, and Zoe Hillock of Las Vegas.

A Memorial service will be scheduled. The family suggests donations to the American Diabetes Association.

Read more from the original source:
Doctor of biochemistry worked at Loma Linda University - Redlands News

Life’s First Genes May Have Contained a Nucleic Acid You’ve Probably Never Heard Of – ScienceAlert

In an effort to trace a pathway from non-evolving organic chemistry to the first truly living cells, scientists from Harvard Medical School in Massachusetts have proposed those early building blocks contained little-known nucleic acids that aren't part of any modern genome.

The question of how we evolved genomic libraries encoded in DNA that are managed by protein-based enzymes and transcribed into notes of short-lived lengths of RNA is fundamental to understanding how life arose on Earth.

The building blocks for both of these ubiquitous chemicals could easily have been present under the hostile conditions on our newborn planet.

But based on what we know of the chemistry giving rise to the well-known nucleic acids RNA and DNA, there's plenty of room for the possibility that other variations could also have formed in the mix.

To understand how this mixture might have behaved, researchers produced nucleotide recipes based on hybrid mixes of not just the familiar ribonucleic (RNA) and deoxyribonucleic acids (DNA), but a sprinkle of something called arabinonucleic acid, or ANA.

The difference between the three different nucleic acids is as subtle as an absent oxygen or a flipped hydroxyl group on the sugar forming the molecule's core.

As small as these contrasts might be, they can make all the difference when it comes to the stability of the polymers they each form under various conditions. Different types of nucleic acids can also mix to form hybrid codes, some of which are more prone to breaking apart than others.

The researchers found when it came to self-replicating, strings of pure RNA did a much better job than other forms of pure nucleic acid, outcompeting them in terms of not just speed, but precision and efficiency.

Surprisingly, by having certain combinations of DNA/ANA hybrids in the environment, RNA did an even better job at replicating, a finding that addresses a long-standing criticism of what's referred to as the RNA World Hypothesis.

Back in the 1960s biologists Carl Woese, Francis Crick, and Leslie Orgel pointed out that RNA had a knack for doing two jobs in one. Even today, it's seen acting as both a means of encoding and performing physical tasks in a cell.

This meant RNA could serve as a convenient prologue for life, forming the basis of an 'RNA world' of competing nucleic acid sequences by playing the role of instruction guide and photocopier.

Unfortunately, 'convenient' is the key word here. Just how did RNA come to be king when surrounded by look-a-likes that could clutter up its machinery?

"Years ago, the naive idea that pools of pure concentrated ribonucleotides might be present on the primitive Earth was mocked by Leslie Orgel as 'the Molecular Biologist's Dream'," says Harvard chemical biologist and Nobel Prize Laureate Jack Szostak.

"But how relatively modern homogeneous RNA could emerge from a heterogeneous mixture of different starting materials was unknown."

Several years ago, Szostak and his team found evidence that hybrid strings of RNA and DNA could help to explain why DNA eventually came to dominate our genomes, in spite of RNA's dual talents.

This newest research complements the discovery by again showing we don't need to explain how RNA or DNA arose separately in their own wet pockets of chemistry.

"No primordial pool of pure building blocks was needed," says Szostak.

What's more, having other types of nucleic acid around including ones no longer being employed by living machines could have actually helped strands of pure RNA dominate, allowing them to take on the most basic tasks of biology and represent a primitive form of life.

"The intrinsic chemistry of RNA copying chemistry would result, over time, in the synthesis of increasingly homogeneous bits of RNA," says Szostak.

Future work could show how other nucleic acids interacted with the burgeoning biochemistry, filling in potential details on life's origins as a chimera of DNA, RNA, ANA, and possibly even other variants we can currently only dream up in a lab.

While we can only speculate on how life arose on Earth several billion years ago, finding evidence of our origins could help us to understand how life might arise elsewhere in the cosmos, not to mention how we might go about creating synthetic alternatives to biology back hereon our home planet.

At this rate, we might need to consider the RNA World Hypothesis as NA.

This research was published in the Journal of American Chemical Society.

Follow this link:
Life's First Genes May Have Contained a Nucleic Acid You've Probably Never Heard Of - ScienceAlert

Biochemical Reagents Market Segmentation 2020 | Analyzing the Impact Followed by Restraints till 2029 – Neptune Pine

A recent market study published by Marketresearch.biz in its upcoming report outlook titled, Biochemical Reagents Market: Global Industry Analysis and Astonishing Growth [2020-2029] offers key market insights and emerging trends on the global Biochemical Reagents market.

The report has offered an exhaustive analysis of the Biochemical Reagents Market taking into consideration all the crucial aspects like growth factors, constraints, market developments, and future prospects. Market researchers and industry experts have pointed out the key market trends and prospects that may impact the overall Biochemical Reagents Market growth. This will help players to leverage the opportunities to strengthen their position. Also, the report throws light on the important factors that are contributing to the Biochemical Reagents Market growth. Additionally, challenges and impeding factors that could hamper the growth of the Biochemical Reagents Market in the years to come are mentioned in the report.

The Biochemical Reagents market report includes comprehensive information about the markets major competitors, including various organizations, companies, associations, suppliers and manufacturers competing for production, supply, sales, revenue generation, and after-sales performance expectations. The bargaining power of numerous vendors and buyers have also been included in the research report.

Download Free PDF Brochure with Full Analysis of Key Players:https://marketresearch.biz/report/biochemical-reagents-market/request-sample

Following Key Players are Analysed in this Report: Beckton, Dickinson & Company, Merck & Co Inc, Abbott Laboratories, Agilent Technologies Inc, Siemens Healthineers, Thermo Fisher Scientific Inc, Bio-Rad Laboratories, Roche Holding AG, Johnson & Johnson, Waters Corporation

Market Dynamics:

Set of qualitative informative data that incorporates PORTER Five Forces Model, Macro-Economic factors, PESTEL Analysis, SWOT Analysis, Value Chain Analysis, Regulatory Framework along with Industry Background and Overview.

Worldwide Biochemical Reagents Research Methodology

Marketresearch.biz presents a detailed picture of the market by way of study, synthesis, and summation of information from various sources. The information thus presented is reliable, comprehensive, and the result of extensive research, both primary and secondary. The analysts have presented the different features of the market with a particular focus on identifying the key business influencers.

Biochemical Reagents Market Data Break Down is illuminated below by product type, end user, and region:

Segmentation by product type:

Polymerase chain reaction (PCR) reagent kitsCell and tissue culture reagentsElectrophoresis reagentsChromatography reagentsOthers (including flow cytometry reagent kits, etc.)Segmentation by end user:

Diagnostic CentersHospitalsAcademics and ResearchPharma and Biotech CompaniesContract Research Organizations (CROs)

The report cast light on an extensive analysis based on the most prominent Biochemical Reagents manufacturers operating in the industry. Activities performed by robust Biochemical Reagents manufacturers/companies are product development, research, and innovation as well as technology adoptions that are intensifying the competitive intensity and companys ability to offer better product lineup. The companies are also performing strategic acquisitions, ventures, mergers, and partnerships to enlarge their serving area and strengthen their existence worldwide.

The study delivers an exact evaluation of the financial operations of companies covering Biochemical Reagents sales volume, capital investment, gross margin, profitability, revenue, cash flow, and growth rate. Their manufacturing capacity, production volume, product specifications, import-export activities, production processes, raw material sourcing, and distribution networks are also elaborated in this Biochemical Reagents report. Companies are also engaged in product launches, promotional activities, and brand developments as part of strategic planning.

How will the report help new companies to plan their investments in the Biochemical Reagents market?

The Biochemical Reagents market research report classifies the competitive spectrum of this industry in elaborate detail. The study claims that the competitive reach spans the companies.

The report also mentions about the details such as the overall remuneration, pricing trends, product sales figures, gross margins, etc.

Information about the sales & distribution area alongside the details of the company, such as company overview, product specifications, buyer portfolio, etc., are provided in the Biochemical Reagents market study.

Inquire/Speak To Expert for Further Detailed Information About Biochemical Reagents Report :https://marketresearch.biz/report/biochemical-reagents-market/#inquiry

Regional Outlook: Regional analysis is another important part of the report which is segregated into different sections. One section of the report is entirely dedicated to regional consumption analysis whereas another for regional production analysis. It includes North America, Europe, China, Japan, Southeast Asia, India.

Some of the Major Highlights of TOC covers in Biochemical Reagents Market Report:

Chapter 1: Methodology & Scope of Biochemical Reagents Market

Definition and forecast parameters

Methodology and forecast parameters

Data Sources

Chapter 2: Executive Summary of Biochemical Reagents Market

Business trends

Regional trends

Product trends

End-use trends

Chapter 3: Biochemical Reagents Industry Insights

Industry segmentation

Industry landscape

Vendor matrix

Technological and innovation landscape

Chapter 4: Biochemical Reagents Market, By Region

Chapter 5: Company Profile

Business Overview

Financial Data

Product Landscape

Strategic Outlook

SWOT Analysis

And CONTINUE

Analysts with high skill in information gathering and governance use industry strategies to collate and examine data at all stages. Our analysts are trained to combine superior research methodology, modern data collection techniques, subject expertise and years of collective experience to deliver useful and accurate research reports.

We will be happy to attend to your queries regarding the above-market study. Kindly contact us atinquiry@marketresearch.bizto learn more about the market report.

Getin Touch with Us:

Mr. Benni Johnson

Prudour Pvt. Ltd.

420 Lexington Avenue,

Suite 300 New York City, NY 10170,

United States

Tel:+ 1-347-826-1876

Website:https://marketresearch.biz/

Thanks a million for reading! You can also request custom information like chapter-wise or specific region-wise study as per your interest.

Continue reading here:
Biochemical Reagents Market Segmentation 2020 | Analyzing the Impact Followed by Restraints till 2029 - Neptune Pine