How to Pronounce Streak – Video


How to Pronounce Streak
Learn how to say Streak correctly with EmmaSaying #39;s "how do you pronounce" free tutorials. Definition of streak (oxford dictionary): noun 1a long, thin line or mark of a different substance or colour from its surroundings: a streak of oil Microbiology a narrow line of bacteria smeared on the surface of a solid culture medium. 2an element of a specified kind in someone #39;s character: there #39;s a streak of insanity in the family Lucy had a ruthless streak [usually with adjective] a continuous period of specified success or luck: the theatre is on a winning streak 3 informal an act of running naked in a public place so as to shock or amuse others: a streak for charity verb 1 [with object] cover (a surface) with streaks: tears streaking her face, Cynthia looked up his beard was streaked with grey dye (hair) with long, thin lines of a different colour to that of one #39;s natural hair colour: [with object and complement]: hair that was streaked blonde Microbiology smear (a needle, swab, etc.) over the surface of a solid culture medium to initiate a culture: swabs were streaked directly on blood agar plates 2 [no object, with adverbial of direction] move very fast in a specified direction: the cat streaked across the street 3 [no object] informal run naked in a public place so as to shock or amuse others: the singer admitted to streaking in his home town in the seventies Phrases like a streak informal very fast: he is off like a streak streak of lightning a flash of lightning: a streak ...

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How to Pronounce Streak - Video

How to Pronounce Streaked – Video


How to Pronounce Streaked
Learn how to say Streaked correctly with EmmaSaying #39;s "how do you pronounce" free tutorials. Definition of streak (oxford dictionary): noun 1a long, thin line or mark of a different substance or colour from its surroundings: a streak of oil Microbiology a narrow line of bacteria smeared on the surface of a solid culture medium. 2an element of a specified kind in someone #39;s character: there #39;s a streak of insanity in the family Lucy had a ruthless streak [usually with adjective] a continuous period of specified success or luck: the theatre is on a winning streak 3 informal an act of running naked in a public place so as to shock or amuse others: a streak for charity verb 1 [with object] cover (a surface) with streaks: tears streaking her face, Cynthia looked up his beard was streaked with grey dye (hair) with long, thin lines of a different colour to that of one #39;s natural hair colour: [with object and complement]: hair that was streaked blonde Microbiology smear (a needle, swab, etc.) over the surface of a solid culture medium to initiate a culture: swabs were streaked directly on blood agar plates 2 [no object, with adverbial of direction] move very fast in a specified direction: the cat streaked across the street 3 [no object] informal run naked in a public place so as to shock or amuse others: the singer admitted to streaking in his home town in the seventies Phrases like a streak informal very fast: he is off like a streak streak of lightning a flash of lightning: a ...

By: Emma Saying

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How to Pronounce Streaked - Video

How to Pronounce Streakers – Video


How to Pronounce Streakers
Learn how to say Streakers correctly with EmmaSaying #39;s "how do you pronounce" free tutorials. Definition of streak (oxford dictionary): noun 1a long, thin line or mark of a different substance or colour from its surroundings: a streak of oil Microbiology a narrow line of bacteria smeared on the surface of a solid culture medium. 2an element of a specified kind in someone #39;s character: there #39;s a streak of insanity in the family Lucy had a ruthless streak [usually with adjective] a continuous period of specified success or luck: the theatre is on a winning streak 3 informal an act of running naked in a public place so as to shock or amuse others: a streak for charity verb 1 [with object] cover (a surface) with streaks: tears streaking her face, Cynthia looked up his beard was streaked with grey dye (hair) with long, thin lines of a different colour to that of one #39;s natural hair colour: [with object and complement]: hair that was streaked blonde Microbiology smear (a needle, swab, etc.) over the surface of a solid culture medium to initiate a culture: swabs were streaked directly on blood agar plates 2 [no object, with adverbial of direction] move very fast in a specified direction: the cat streaked across the street 3 [no object] informal run naked in a public place so as to shock or amuse others: the singer admitted to streaking in his home town in the seventies Phrases like a streak informal very fast: he is off like a streak streak of lightning a flash of lightning: a ...

By: Emma Saying

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How to Pronounce Streakers - Video

How to Pronounce Streaks – Video


How to Pronounce Streaks
Learn how to say Streaks correctly with EmmaSaying #39;s "how do you pronounce" free tutorials. Definition of streak (oxford dictionary): noun 1a long, thin line or mark of a different substance or colour from its surroundings: a streak of oil Microbiology a narrow line of bacteria smeared on the surface of a solid culture medium. 2an element of a specified kind in someone #39;s character: there #39;s a streak of insanity in the family Lucy had a ruthless streak [usually with adjective] a continuous period of specified success or luck: the theatre is on a winning streak 3 informal an act of running naked in a public place so as to shock or amuse others: a streak for charity verb 1 [with object] cover (a surface) with streaks: tears streaking her face, Cynthia looked up his beard was streaked with grey dye (hair) with long, thin lines of a different colour to that of one #39;s natural hair colour: [with object and complement]: hair that was streaked blonde Microbiology smear (a needle, swab, etc.) over the surface of a solid culture medium to initiate a culture: swabs were streaked directly on blood agar plates 2 [no object, with adverbial of direction] move very fast in a specified direction: the cat streaked across the street 3 [no object] informal run naked in a public place so as to shock or amuse others: the singer admitted to streaking in his home town in the seventies Phrases like a streak informal very fast: he is off like a streak streak of lightning a flash of lightning: a ...

By: Emma Saying

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How to Pronounce Streaks - Video

How to Pronounce Streaker – Video


How to Pronounce Streaker
Learn how to say Streaker correctly with EmmaSaying #39;s "how do you pronounce" free tutorials. Definition of streak (oxford dictionary): noun 1a long, thin line or mark of a different substance or colour from its surroundings: a streak of oil Microbiology a narrow line of bacteria smeared on the surface of a solid culture medium. 2an element of a specified kind in someone #39;s character: there #39;s a streak of insanity in the family Lucy had a ruthless streak [usually with adjective] a continuous period of specified success or luck: the theatre is on a winning streak 3 informal an act of running naked in a public place so as to shock or amuse others: a streak for charity verb 1 [with object] cover (a surface) with streaks: tears streaking her face, Cynthia looked up his beard was streaked with grey dye (hair) with long, thin lines of a different colour to that of one #39;s natural hair colour: [with object and complement]: hair that was streaked blonde Microbiology smear (a needle, swab, etc.) over the surface of a solid culture medium to initiate a culture: swabs were streaked directly on blood agar plates 2 [no object, with adverbial of direction] move very fast in a specified direction: the cat streaked across the street 3 [no object] informal run naked in a public place so as to shock or amuse others: the singer admitted to streaking in his home town in the seventies Phrases like a streak informal very fast: he is off like a streak streak of lightning a flash of lightning: a ...

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How to Pronounce Streaker - Video

Bruker and Erasmus Medical Center Sign an Exclusive Licensing Agreement for Adding Rapid Beta-Lactamase Testing …

BREMEN, Germany--(BUSINESS WIRE)--

Bruker today announces an exclusive licensing agreement with Erasmus Medical Center, Rotterdam, The Netherlands for rapid testing of beta-lactamase activity using MALDI-TOF technology. This new method is fully compatible with the well-established Bruker MALDI Biotyper system, which is used for MALDI-TOF mass spectrometry-based identification of microorganisms in over 700 clinical and non-clinical microbiology laboratories worldwide.

In many laboratories, the MALDI Biotyper has replaced classical biochemical testing for bacterial identification in the past five years due to the accuracy, speed, extensive species coverage, ease of use and cost effectiveness of the system. Classical biochemical techniques depend upon detecting different metabolic properties of microorganisms; however, these techniques can take hours or even days for completion and they lack specificity. The MALDI Biotyper uses a molecular approach based on specific proteomic fingerprints from bacterial and fungal strains and published studies have highlighted the greater accuracy offered, as well as the typically much faster time-to-result (TTR). With an installed base of more than 700 MALDI Biotyper systems at the end of 2012, Bruker estimates that in the year 2012 its customers performed about 20 million microbial identifications on the MALDI Biotyper installed base.

In addition to this paradigm shift for microbial identification, the MALDI Biotyper is increasingly being used for functional resistance mechanism detection. Antibiotic resistance is an ever increasing problem as bacteria acquire new mechanisms of resistance against classes of antibiotics currently being used in clinical care. Data from the WHO European Region shows that resistance of some pathogens now reaches over 50% in some countries, and new resistance mechanisms are emerging and spreading rapidly. In the European Union, Norway and Iceland it is estimated that 400,000 resistant infections are occurring every year, leading to approximately 25,000 deaths.

Gram-negative bacteria are a common source of infections and pose significant challenges due to their ability to rapidly acquire new resistance mechanisms resulting in multi-drug resistant (MDR) strains. One such mechanism of resistance found in gram-negatives is Extended Spectrum Beta-Lactamase (ESBL) in which enzymes produced by bacteria attack and cleave the beta-lactam ring in antibiotics, thus rendering them ineffective. This includes penicillins, and third generation cephalosporins. Another mechanism is resistance to Carbapenems, which frequently are the drugs of last resort for clinicians when other antibiotics have been ineffective due to resistance.

Consumption of carbapenems increased significantly in European countries from 2007-2010 and occurrence of carbapenem-resistant Klebsiella pneumonia is already high and increasing in some European countries. Recent publications in both the scientific and popular press have high-lighted the challenge and outbreaks associated with microorganisms containing ESBL mechanisms including reports on NDM-1, KPC and most recently CRE (Carbapenem-Resistant Enterobacteriaceae). Accurate and rapid detection of resistance is essential for effective infection control measures, as current techniques lack either specificity or rapid turn-around time.

MALDI-TOF mass spectrometry allows for an exact determination of the molecular weight of a broad range of antibiotics. In the presence of an ESBL, the antibiotic is converted to fragments of predictable molecular weight which are also measured using the MALDI Biotyper. As with bacterial identification, the MALDI Biotyper is thus anticipated to provide both improved, shorter time-to-result as well as potentially better specificity.

Dr. Theo Luider, Head of the Laboratories of Neuro-Oncology, Department of Neurology, Erasmus University of Rotterdam, pointed out: We have been working with MALDI-TOF mass spectrometry for many years originally in the field of clinical proteomics, but more recently the increased usage of the MALDI-TOF approach for microbial identification also became an area of interest for us. We have filed a PCT patent for the characterization of beta-lactamase activity by MALDI-TOF mass spectrometry with the title "Methods and means for characterizing antibiotic resistance in microorganisms". With their outstanding expertise in mass spectrometry and clinical microbiology market presence, we think that Bruker is the right partner to bring such novel assays to the market.

Dr. Stefan Zimmermann, Department of Infectious Disease, Medical Microbiology and Hygiene,at the University Hospital Heidelberg, commented: We have been using MALDI Biotyper-based functional beta-lactamase assays in our hospital for roughly two years with the main application being epidemiology and hospital hygiene. It is of great importance to know as early as possible, especially in the intensive care unit, if a new patient carries a carbapenem-resistant Klebsiella pneumonia (KPC). In this case we are able to isolate the patient sooner than with older phenotypic methods. MALDI Biotyper-based KPC-testing improves patient health and at the same time improves cost-efficiency of the Intensive Care Unit by limiting the isolation of patients to those cases where it is really necessary.

Dr. Wolfgang Pusch, Executive Vice President - Microbiology Business at Bruker Daltonics, added: The signing of this exclusive license agreement with the Erasmus Medical Center is another major milestone in our MALDI Biotyper strategy. While MALDI Biotyper-based microbial identification is already established in many countries, we see significant growth potential in MALDI-based beta-lactamase testing. The exclusively licenced IP from Erasmus Medical Center further strengthens our own broad portfolio of intellectual property in the field of mass spectrometry-based microbial analysis ranging from sample preparation, data processing, MALDI-TOF technology, direct analysis from positive blood cultures and beta-lactamase testing, and offers laboratories worldwide another tool in the fight against resistant bacteria.

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Bruker and Erasmus Medical Center Sign an Exclusive Licensing Agreement for Adding Rapid Beta-Lactamase Testing ...

Woods Hole research projects awarded $5.2 million

The Woods Hole Oceanographic Institution (WHOI) has received $5.2 million in 2012 from the Gordon and Betty Moore Foundations Marine Microbiology Initiative, according to a press release. The money will fund three projects aimed at better understanding the complex role that marine microbes play in the ocean ecosystem and to better assess the oceans health and productivity.

Their work will look for answers to questions regarding the flow of nutrients through microbial food webswho eats and secretes what, where, and whenand the resulting biogeochemical transformations.

The support of the Gordon and Betty Moore Foundation is critical to enabling a fundamental understanding of microbes contribution to ocean health and productivity, says WHOI President and Director Susan Avery. There is so much more to know about marine microbes genetic diversity, how they secure nutrients, what other organisms they interact with, and the biogeochemical changes they bring about in the ocean. These new projects will contribute toward the ultimate goal of a comprehensive understanding of marine microbial communities.

The funded projects at WHOI include:

The introduction of improved instrumentation for geochemical analysis and powerful new molecular biology techniques for studying genomes and gene and protein expression has given us new ways of looking at how microbes function in the marine environment, says Ajit Subramaniam, program director for the Marine Microbiology Initiative. With Moore Foundation support, we want to enable multidisciplinary teams of scientists to identify and quantify nutrient pools in the ocean, and decipher the genetic and biochemical bases of microbial metabolism.

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Woods Hole research projects awarded $5.2 million

In Memoriam: Carl Woese

The astrobiology community deeply mourns the loss of Dr. Carl Woese, the University of Illinois microbiology professor credited with the discovery of a "third domain" of life. He died on Sunday, December 30th at his home. He was 84.

In 1977, Dr. Woese and his colleagues overturned a universally held assumption about the basic structure of the tree of life. Microbes known as archaea are as distinct from bacteria as plants and animals are, they wrote in a published paper. Prior to this finding, scientists had lumped archaea together with bacteria and asserted that the tree of life had two main branches -- bacteria (called prokarya), and everything else (eukarya). Their discovery added archaea as a third main branch of the evolutionary family tree.

Dr. Woese was born on July 15, 1928, in Syracuse, N.Y. He earned bachelor's degrees in math and physics from Amherst College and a Ph.D. in biophysics at Yale University. He studied medicine at the University of Rochester, was a postdoctoral researcher in biophysics at Yale and worked as a biophysicist at the General Electric Research Laboratory in Schenectady, N.Y. before he joined the microbiology faculty at the University of Illinois in 1964. He was also a professor at the UI's Institute for Genomic Biology.

"Carl was truly a man of vision, creativity and passion, with a deep love of this university," said Gene Robinson, director of the UI's Institute for Genomic Biology in a statement. "Carl not only rewrote the textbook in evolutionary biology, but his discovery also has given us the tools today to study the human microbiome, the incredibly diverse and complex assemblages of microorganisms in our bodies that contribute so much to both health and disease."

Woese received a number of awards for his research: a MacArthur Foundation grant in 1984, election to the National Academy of Sciences in 1988, the Leeuwenhoek Medal (microbiology's premier honor from the Royal Netherlands Academy of Arts and Sciences) in 1992, a National Medal of Science in 2000 and many more.

Source: [University of Illinois]

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In Memoriam: Carl Woese

Dopamine-receptor gene variant linked to human longevity

Public release date: 3-Jan-2013 [ | E-mail | Share ]

Contact: Tom Vasich tmvasich@uci.edu 949-824-6455 University of California - Irvine

Irvine, Calif., Jan. 3, 2013 A variant of a gene associated with active personality traits in humans seems to also be involved with living a longer life, UC Irvine and other researchers have found.

This derivative of a dopamine-receptor gene called the DRD4 7R allele appears in significantly higher rates in people more than 90 years old and is linked to lifespan increases in mouse studies.

Robert Moyzis, professor of biological chemistry at UC Irvine, and Dr. Nora Volkow, a psychiatrist who conducts research at the Brookhaven National Laboratory and also directs the National Institute on Drug Abuse, led a research effort that included data from the UC Irvine-led 90+ Study in Laguna Woods, Calif. Results appear online in The Journal of Neuroscience.

The variant gene is part of the dopamine system, which facilitates the transmission of signals among neurons and plays a major role in the brain network responsible for attention and reward-driven learning. The DRD4 7R allele blunts dopamine signaling, which enhances individuals' reactivity to their environment.

People who carry this variant gene, Moyzis said, seem to be more motivated to pursue social, intellectual and physical activities. The variant is also linked to attention-deficit/hyperactivity disorder and addictive and risky behaviors.

"While the genetic variant may not directly influence longevity," Moyzis said, "it is associated with personality traits that have been shown to be important for living a longer, healthier life. It's been well documented that the more you're involved with social and physical activities, the more likely you'll live longer. It could be as simple as that."

Numerous studies including a number from the 90+ Study have confirmed that being active is important for successful aging, and it may deter the advancement of neurodegenerative diseases, such as Alzheimer's.

Prior molecular evolutionary research led by Moyzis and Chuansheng Chen, UC Irvine professor of psychology & social behavior, indicated that this "longevity allele" was selected for during the nomadic out-of-Africa human exodus more than 30,000 years ago.

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Dopamine-receptor gene variant linked to human longevity

The First Functionally Interpretable Systems Biology Platform for Personalized Medicine and Drug Development

EMERYVILLE, Calif.--(BUSINESS WIRE)--

KineMed, Inc. (www.kinemed.com) announced today that David Fineman, KineMeds CEO will present at the 2013 Biotech Showcase Conference on Monday, January 7th at 2:00 p.m. on the 4th floor of the Parc 55 Windham Hotel -- Union Square, San Francisco.

Mr. Finemans presentation entitled Functionally Interpretable Translational Biomarkers for the Next Generation of Disease Management will present powerful examples of KineMeds new class of kinetic biomarker across the spectrum of medicines development and clinical care, from identifying the molecular causes of disease, to the pairing of drugs with diagnostics to treat patients more effectively.

KineMeds unique signatures of disease state are derived from its proprietary Network Dynamics platform, which reveals causal relationships underlying the biology of disease mechanisms. These measurements of change are derived from ultra-sensitive, high-throughput mass spectroscopy of the entire proteome and metabolome.

As our industry looks towards personalized medicine and the next generation of disease management, the indispensable role of biomarkers becomes increasingly clear, said Mr. Fineman. We are offering a truly universal method that is fully translational from preclinical R&D to clinical diagnostic measurements, all from a single drop of blood. At Biotech Showcase 2013, we will highlight successful examples of our unique approach across key indications including neurodegeneration, muscle wasting and fibrotic disease, showing how these techniques are becoming central to mainstream pharmaceutical development and disease management strategies.

About Biotech Showcase

Biotech Showcase is an investor and partnering conference devoted to providing private and public biotechnology and life sciences companies an opportunity to present to, and meet with, investors and pharmaceutical executives during the course of one of the industrys largest annual healthcare investor conferences. Now in its fifth year, Biotech Showcase is expected to attract upwards of 1,500 attendees.

For more information about Biotech Showcase, please visit:http://www.ebdgroup.com/bts/index.php.

About KineMed, Inc.

KineMed, Inc., is a leading diagnostic biomarker discovery and drug development company focused on causal pathway discovery and the pairing of medicines with diagnostics for integrated disease management. KineMed works with collaborators and clients to develop biomarkers that provide predictive, actionable information to dramatically improve, de-risk and accelerate drug discovery, development and disease management decisions. KineMeds technology reveals dynamic causal processes of disease rather than isolated molecular targets and provides precise measures of therapeutic effectiveness on these processes, offering yes/no to key treatment questions: Is this drug right for the patient? and Is the drug working?

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The First Functionally Interpretable Systems Biology Platform for Personalized Medicine and Drug Development

CLU professor working to change college biology instruction

Scientists and educators think they know how to keep students studying biology in college rather than giving up in frustration after an especially difficult course or two. They know, for example, that students must explore scientific concepts rather than just memorizethem.

The problem is the recommendations a national group has made remain just recommendations. Now another group is working to take those ideas from theory to practice in universitiesnationwide.

That group includes David Marcey, a professor at California Lutheran University in Thousand Oaks. Marcey is one of 40 fellows selected for the Partnership for Undergraduate Life Science Education, which is trying to improve how colleges teach lifesciences.

The work is important because so many students give up on biology or other life sciences after sometimes challenging, but essential, courses such as freshman biology, Marceysaid.

"We have a very leaky ... pipeline," Marcey said. "Many students are interested in science entering college, and the attrition rate is phenomenal, especially among underrepresented groups" low-income students and those who are the first in their families to go tocollege.

Marcey's group has a year to take recommendations from the American Association for the Advancement of Science and the National Science Foundation and start making them reality. The group met for the first time in October and will meet again in June. Meanwhile, it has broken into four groups that talk monthly byphone.

"We're trying to build a framework that will spark the adoption of (those) recommendations at the department level nationally," Marceysaid.

Some universities already have adopted the group's overall approach, including the University of San Diego, where Rick Gonzalez, a member of the group, teachesbiology.

When Gonzalez teaches freshmen, he sends them out to do their own investigations, like having them find 30 plants of the same species, measure the plants' leaves and collect thedata.

"They're actually asking questions, then making measurements to answer those questions," Gonzalezsaid.

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CLU professor working to change college biology instruction

University of Toronto Biochemistry Year-End Party Dec. 14, 2012 – Video


University of Toronto Biochemistry Year-End Party Dec. 14, 2012
Science songs written by Profs. John Glover and David Williams and performed with Grad Student Debbie Hong. The PhD Hallelujah I have done it all I #39;m dreaming of a white lab coat (see lyrics below) The Ph.D. Hallelujah Lyrics: Glover/Williams Music: Leonard Cohen Sometimes it seems...

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University of Toronto Biochemistry Year-End Party Dec. 14, 2012 - Video

How to Pronounce Deaminase – Video


How to Pronounce Deaminase
Learn how to say Deaminase correctly with EmmaSaying #39;s "how do you pronounce" free tutorials. Definition of adenosine deaminase (oxford dictionary): noun [mass noun] Biochemistry an enzyme which catalyses the deamination of adenosine to inosine. http://www.emmasaying.com Take a look at my comparison tutorials here http://www.youtube.com Subscribe to my channel here : http://www.youtube.com

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How to Pronounce Deaminase - Video

How to Pronounce Deaminated – Video


How to Pronounce Deaminated
Learn how to say Deaminated correctly with EmmaSaying #39;s "how do you pronounce" free tutorials. Definition of deamination (oxford dictionary): noun [mass noun] Biochemistry the removal of an amino group from an amino acid or other compound. Derivatives deaminated adjective http://www.emmasaying.com Take a look at my comparison tutorials here http://www.youtube.com Subscribe to my channel here : http://www.youtube.com

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How to Pronounce Deaminated - Video

Intelligent Nutrition, Peter J Clark – Video


Intelligent Nutrition, Peter J Clark
Nutrition Clinic¶Specialist one to one advice for stubborn weight, digestive problems (IBS), food intolerances, fatigue, stress, and other common health concerns.¶¶Sports Clubs and Individual Athletes¶We offer bespoke seminars and workshops for sports clubs, tailored to your requirements, and individual sports nutrition programmes.¶¶Businesses and Organisations¶We run health training seminars, workshops and one to one nutritional coaching to help reduce staff sickness, tackle obesity and heart disease, and manage stress and anxiety.¶¶We have over 20 years of expertise to provide you with the support and intelligent solutions you need. We are a friendly, professional practice based in Leeds, West Yorkshire.¶¶Intelligent Nutrition was set up by and is directed by our Nutritionist Peter Clark BSc (Hons), MMedSci (Human Nutrition), registered with BANT, NTC and CNHC. Peter has a degree in Biochemistry, a Masters in Human Nutrition (with distinction) and has been published in the Lancet., 47, Gledhow Wood Rd, Leeds, West Yorkshire, LS8 4DG, http://www.yell.com

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Intelligent Nutrition, Peter J Clark - Video