Health care rally draws hundreds

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SALEM Hundreds of people from all over Oregon rallied in Salem on the first day of the legislative session to call attention to what they claim is a broken health care system and call on lawmakers to enact reforms.

An estimated 1,000 protesters, many brandishing signs and wearing red Health Care Is a Human Right T-shirts, packed the Capitol steps to hear a dozen speakers tell horror stories of out-of-control medical costs and urge support for a single-payer health care bill.

Ten buses including two from the mid-valley delivered people from as far away as La Grande and Bandon, Ashland and Prineville for the lunchtime rally, organized by Health Care for All Oregon.

Rep. Michael Dembrow, D-Portland, got a hearty cheer as he took the stage to talk about his plans to reintroduce the Affordable Health Care for All Oregon Act, which foundered in the 2011 session.

This time, he said, the notion of a comprehensive taxpayer-supported health care system for all Oregonians has broader support, with 19 co-sponsors already on board, compared to 11 last time.

But he also predicted that a statewide ballot measure would ultimately be required to enact a single-payer system in Oregon. Using emotionally charged language, he exhorted the audience to work toward passing an initiative in the 2016 election.

Brothers and sisters, Dembrow said, the real work here is not going to be done inside this building. Its going to be done outside this building, in all parts of Oregon, by all of you.

Two of his co-sponsors, Reps. Jennifer Williamson of Portland and Dave Gomberg of Lincoln City, also spoke in support of the bill.

Mondays rally had a festive air, with musicians performing protest songs, a 10-foot-tall puppet dubbed Big Nurse, and activists wearing open-backed hospital gowns that exposed padded foam derrierres to illustrate what private insurance just wont cover.

The crowd, roughly six times the size of a similar gathering two years ago to support Dembrows previous single-payer bill, chanted and sang, cheered and shouted for a parade of speakers lamenting the ills of private heath insurance.

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Health care rally draws hundreds

Tailored gene therapy approach could replace drug treatments for HIV patients

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One of the biggest problems in treating HIV patients is the amount of daily individual medications it takes to keep the virus at bay. In a new study, scientists at the Stanford University School of Medicine have engineered a new approach to tailored gene therapy that they say makes key cells of the immune system resistant to attack from the HIV virus, which may eventually lead to the removal of life-long dependencies on drugs for patients living with HIV.

The drug treatment regime for HIV is intended to block the reception of the virus at different stages of the replication process. Unfortunately, the virus itself is known to mutate and thats why a selection of medications, known as highly active antiretroviral therapy (HAART), is required to stave off potentially fatal infections. Researchers at Stanford have added to previous experiments by cutting and pasting a series of HIV-resistant genes into the immune cells that are targeted by the virus, known as T-cells, thereby simulating the HAART treatment through genetic manipulation.

Typically, HIV enters T-cells by latching onto one of two surface proteins known as CCR5 and CXCR4. However, a small number of people carry a mutation in CCR5, making them more resistant to HIV. The results of this are exemplified by the now-famous Berlin Patient, a leukemia sufferer with the HIV virus, who received a bone-marrow transplant and was subsequently cured of HIV, thanks to the donor carrying the mutated CCR5 gene.

This new study builds on previous work by scientists at Sangamo BioSciences in California who developed a technique using a protein that recognizes and binds to the CCR5 receptor gene, genetically modifying it to mimic the naturally resistant version. This technique uses a protein that can break up pieces of DNA, known as a zinc finger nuclease, to effectively inactivate the receptor gene.

The Stanford researchers have now used the same nuclease to create a break in the CCR5 receptors' DNA, within which they pasted three genes known to hold back the virus. The technique of placing these genes in one site is known as stacking. The study also states that, Incorporating the three resistant genes helped shield the cells from HIV entry via both the CCR5 and CXCR4 receptors. The disabling of the CCR5 gene by the nuclease, as well as the addition of the anti-HIV genes, created multiple layers of protection.

This form of tailored gene therapy, which blocks both the CCR5 and CXCR4 has not been achieved before. The stacked triplet of anti-HIV genes created an effective barrier of more than 1,200-fold protection for the CCR5 gene and more than 1,700-fold for the CXCR4 (based off an unaltered T-cell), which is a much higher success rate than tests with only one or two alterations. Comparatively, the unaltered T-cell became infected within 25 days.

However, the technique is not without drawbacks. A concern is that creating a break in one part of the cell may lead to an unintended break elsewhere, which may cause cancer or other cell aberrations. The study also says that Its possible the cells wont like the proteins theyre asked to express, and wont grow.

Those challenges aside, the news is promising for the development of delivering individually tailored, virus resistant T-cells to an infected patient. Because the method will be on a patient-by-patient basis it will be time consuming, and though it will not kill the virus, it may free patients of the need to take strong antiretroviral medications that keep their immune system from collapsing. The researchers hope to begin clinical trials within three to five years.

The study appears in the Jan. 22 issue of Molecular Therapy.

Source: Stanford School of Medicine

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HEAR THIS | Gene therapy in mice boosts hope for the deaf

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By: Agence France-Presse February 5, 2013 6:32 AM

AFP FILE PHOTO

InterAksyon.com The online news portal of TV5

PARIS - Scientists using gene therapy have partially restored hearing and balance in profoundly deaf mice, according to a study published on Monday in the journal Nature Medicine.

The research, still in its early stages and restricted to lab animals, may open up new avenues for tackling Usher syndrome, an inherited form of human deafness that usually goes hand in hand with blindness.

Researchers led by Michelle Hastings at the Rosalind Franklin University of Medicine and Science in Chicago, Illinois, aimed at a gene called USH1C which has been implicated in the "Type 1" form of Usher syndrome.

USH1C controls a protein called harmonin, which plays a vital role in hair cells -- the cells in the cochlea of the inner ear that respond to sound waves and send an electrical signal to the brain.

The team devised a tiny strand of genetic material called an antisense oligonucleotide to "switch off" a faulty version of the gene that produces truncated forms of the protein.

The therapy was injected in newborn mice that had been genetically engineered to have the mutation.

A single injection partially restored their hearing at very low frequencies, and also reduced head tossing, a behavior caused by impaired balance.

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HEAR THIS | Gene therapy in mice boosts hope for the deaf

Creation of an International Gene Therapy Consortium

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QUEBEC, Feb. 4, 2013 /CNW Telbec/ - In the latest issue of the journal Molecular Therapy, Professor Jacques P. Tremblay (president of the Association of Gene Therapy of Quebec and researcher in the Research center of the Centre Hospitalier Universitaire (CHU) of Quebec) launches a call - with 50 other world experts in gene therapy - for the creation of an International Gene Therapy Consortium for Monogenic Diseases. The bases of this consortium will be established during a workshop, which will be held during the congress of the American Society of Gene and Cell Therapy (ASGCT) in Salt Lake City in May 2013.

Recent scientific progress in molecular biology and in genomics allowed during the recent years to identify the genes responsible for 10,000 hereditary diseases caused by a mutation in a single gene (for ex., Duchenne muscular dystrophy, Friedreich ataxia, haemophilia, etc.). On the other hand, recent progress of gene therapy resulted in treatments for some of these diseases previously considered incurable: hereditary immuno-deficiencies (the bubble children), a form of hereditary blindness (congenital amaurosis of Leber), etc. Also, for the first time, a gene-therapy treatment was approved for commercialization in Europe (for familial hyperchylomicronemia, a lipid disease). A Quebec team participated in the development of this treatment. The discovery of pluripotent stem cells, for which Dr. Yamanaka obtained the Nobel Prize in Medicine 2012, also allows to genetically correct the patient own cells and to differentiate them in various types of cells including those of heart and brain. These cells could then be re-transplanted to the patient without immunosuppression.

The research to develop treatments for these hereditary illnesses is at present made by small teams often financially supported by small patient associations. This fragmentation of the research and the sub-financing make more difficult the development of clinical trials. Professor Tremblay and his cosignatories indicate that with sufficient budgets, it would be possible to develop globally therapies for the most of these diseases during the next 2 decades.

The Regroupement qubcois des maladies orphelines (Quebec Coalition of Orphan Diseases) encourages initiatives that help develop treatments for rare genetic disorders.

The article that calls for the creation of the Consortium: Translating the Genomics Revolution: The Need for an International Gene Therapy Consortium for Monogenic Diseases, Molecular Therapy, February 2013.

SOURCE: Regroupement qubcois des maladies orphelines

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Creation of an International Gene Therapy Consortium

Gene Therapy Restores Hearing in Deaf Mice

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A new gene therapy tested on deaf mice proved to partially restore hearing and balance, giving hope to many who suffer from Usher syndrome, a form of human deafness that usually comes with blindness.

While the research, which was published in the journal Natural Medicine, is still in its early stages and has not been tested on humans, it has made many hopeful of a future therapy for the deaf.

Michelle Hastings, lead researcher, focused in on a gene called USH1C, which is "Type 1" of Usher syndrome.

The role of the gene is to produce a protein called harmonin, which plays an important role in hair cells. Our hearing is processed in the cochlea of the inner ear, where these hair cells are located, and an electrical signal is sent to the brain.

The team created a strand of genetic material called an antisense oligonucleotide to "switch off" a faulty gene that truncates forms of harmonin, leading to deafness.

Once this therapy was inserted into mice that were born with the mutation, their hearing was restored at low frequency. It also reduced head tossing, a behavior that occurs when balance is impaired.

"These effects were sustained for several months, providing evidence that congenital deafness can be effectively overcome by treatment early in development to correct gene expression," the study said.

After the experiment concluded, the mice were dissected and researchers found their cochleas to have grown some hair cells.

Much progress has been made recently in researching potential treatments for the deaf.

In January, doctors at the Massachusetts Eye and Ear and Harvard Medical School reported on another gene drug that transformed cochlea cells into hair cells.

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Gene Therapy Restores Hearing in Deaf Mice

Gene therapy boosts hope for the deaf

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Scientists using gene therapy have partially restored hearing and balance in profoundly deaf mice, according to a study published in the journal Nature Medicine.

The research, still in its early stages and restricted to lab animals, may open up new avenues for tackling Usher syndrome, an inherited form of human deafness that usually goes hand in hand with blindness.

Researchers led by Michelle Hastings at the Rosalind Franklin University of Medicine and Science in Chicago, Illinois, aimed at a gene called USH1C, which has been implicated in the 'Type 1' form of Usher syndrome.

USH1C controls a protein called harmonin, which plays a vital role in hair cells - the cells in the cochlea of the inner ear that respond to sound waves and send an electrical signal to the brain.

The team devised a tiny strand of genetic material called an antisense oligonucleotide to 'switch off' a faulty version of the gene that produces truncated forms of the protein.

The therapy was injected in newborn mice that had been genetically engineered to have the mutation.

A single injection partially restored their hearing at very low frequencies, and also reduced head tossing, a behaviour caused by impaired balance.

'These effects were sustained for several months, providing evidence that congenital deafness can be effectively overcome by treatment early in development to correct gene expression,' the study says.

After the experiment, the mice were dissected, and their cochleas were found to have grown some hair cells.

The success of antisense oligonucleotides adds a further weapon in the quest to overcome deafness.

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Gene therapy boosts hope for the deaf

Healthcare Futurist Jack Uldrich to Keynote Methodist Hospital and United Healthcare Events

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Acclaimed healthcare futurist and best-selling author, Jack Uldrich has been selected to deliver two more keynote presentations in the spring of 2013. He will address the board members of the Methodist Hospital in Houston in February and then headline United Healthcare's Valued Customer Forum in May.

San Francisco, CA (PRWEB) February 04, 2013

The presentations, based on Uldrichs two most recent books: "Foresight 20/20: A Futurist Explores the Trends Transforming Tomorrow" and "Higher Unlearning: 39 Post Requisite Lessons for Achieving a Successful Future"--as well as his popular article, "Top Ten Trends in Healthcare"--will begin by discussing how continued advances in information technologies, biotechnology, nanotechnology, robotics, radio frequency identification (RFID) technology, genomics, regenerative medicine and social networking will radically transform healthcare in the decade ahead. (A video of Mr. Uldrich discussing future trends can be viewed here.)

Uldrich will then focus on why these trends will demand unlearning and discuss why participants must embrace the concept of unlearning in order to achieve future success. Uldrich, who has been hailed as Americas Chief Unlearning Officer, will conclude by reviewing specific habits, customs, beliefs and ideas that healthcare professionals canand mustunlearn. Throughout his talks, he will use vivid analogies and memorable stories, drawn from a wide spectrum of industries, to ensure his message of unlearning sticks with his audiences.

In the past year, Uldrich has addressed dozens of healthcare associations and hospitals, including the Alcetel-Lucent/Verizon Forum on Wireless Healthcare, IASIS Healthcare, Allina Hospitals, The Healthcare Trustees of New York, The Iowa Healthcare Collaborative, Care Providers of Minnesota, St. Jude Medical, Fairview Hospitals, University Hospitals & Health System of Ohio, and healthcare associations in Arizona, Colorado, Illinois, Kansas, Maine, Maryland, Minnesota, Mississippi, Montana, Nebraska, Tennessee, Utah and Wisconsin. He has also addressed a number of major, non-health-care-related corporations on the topic of unlearning including PepsiCo, Cisco, IBM, WiPro, Guardian Life Insurance and General Electric. Uldrich also frequently addresses Young Presidents Organization (YPO) and Chamber of Commerce events throughout the country.

Parties interested in learning more about Jack Uldrich, his books, his daily blog or his speaking availability are encouraged to visit his website at: http://www.jumpthecurve.net. Media wishing to know more about the event or interviewing Jack Uldrich can contact him directly at 612-267-1212 or jack(at)schoolofunlearning(dot)com.

Uldrich is a renowned global healthcare futurist, best-selling author; editor of the monthly newsletter, The Exponential Executive, and host of the award-winning websites, http://www.jumpthecurve.net and http://www.schoolofunlearning.com. He is currently represented by a number of professional speakers bureaus, including Leading Authorities, Executive Speakers Bureau and Convention Connection.

Jack Uldrich Jump the Curve 612-267-1212 Email Information

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Healthcare Futurist Jack Uldrich to Keynote Methodist Hospital and United Healthcare Events

Pop album review: Tim McGraw's brawnier 'Two Lanes of Freedom'

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"Two Lanes of Freedom" is Tim McGraw's first album since he announced that he gave up alcohol five years ago. It's also his first record for Big Machine appropriately, also Taylor Swift's home label, given her single "Tim McGraw" and he looks hale and hearty in the album's accompanying videos.

It all signals a major new start for McGraw, one of pop-country's bestselling but critically assailed figures. If only the songs on "Two Lanes" were as honed and wiry as their singer. The album should keep him atop the country commercial firmament, but doesn't really advance him as an artist.

The record is brawnier than most of McGraw's catalog, with lead single "One of Those Nights" built on the rock guitar riffing that McGraw and Co. showcased on a recent stadium tour with Kenny Chesney. But the writing is as modern-country-boilerplate as it comes an ode to drinking away a heartbreak in Mexico ("Mexicoma," a pun that borders on Nashville-factory camp), a paean to hillbilly life ("Truck Yeah") that's flagrant in its attempt to coin a party slogan.

"Highway Don't Care," McGraw's collaboration with Swift and Keith Urban, is a blowout of a send-off ballad, and we're glad McGraw beat his demons and is looking great. But it's a shame he didn't take the musical chances that can also mark a new beginning.

Tim McGraw

"Two Lanes of Freedom"

Big Machine

Two stars (out of four)

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Pop album review: Tim McGraw's brawnier 'Two Lanes of Freedom'

CEA Reinforces Call for Internet Freedom

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ARLINGTON, Va.--(BUSINESS WIRE)--

The following statement is attributable to Gary Shapiro, president and CEO of the Consumer Electronics Association (CEA), regarding todays joint U.S. House of Representatives hearing on Internet freedom:

The open and uncensored Internet is a great engine of social and economic progress but it is under threat.Through the United Nations agency, the International Telecommunication Union (ITU), a number of countries areattempting to establish greater governmental control of the Internet. Their efforts, if successful, could destroy the open and innovative technology platform that millions around the world need and trust.

As the worlds technology leader, it is essential that the United States persuade other nations of the benefits of an open Internet. We must provide the example. We must continue to walk the walk, not just talk about preserving Internet Freedom.

We commend the Commerce and Foreign Affairs Committees for todays hearing reinforcing Americas commitment to keeping the Internet open and safe from government censorship and interference. We look forward to working with Congress to protect and promote a global Internet free from government control.

About CEA:

The Consumer Electronics Association (CEA) is the preeminent trade association promoting growth in the $209 billion U.S. consumer electronics industry. More than 2,000 companies enjoy the benefits of CEA membership, including legislative advocacy, market research, technical training and education, industry promotion, standards development and the fostering of business and strategic relationships.CEA also owns and produces the International CES The Global Stage for Innovation. All profits from CES are reinvested into CEAs industry services.Find CEA online at http://www.CE.org, http://www.DeclareInnovation.com and through social media: https://www.facebook.com/#!/CEAfeed http://twitter.com/ceafeed http://blog.ce.org/.

UPCOMING EVENTS

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CEA Reinforces Call for Internet Freedom

McGraw hits the road with 'Two Lanes of Freedom'

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NASHVILLE, Tenn. (AP) Tim McGraw is free.

The country star has moved on from a troubling label, quit drinking and grown up a bit, and all that has given McGraw a new energy he says you can hear on his latest album, "Two Lanes of Freedom."

"I think this record is definitely sort of a flag in the ground for me," McGraw said.

His first release with Big Machine Records has been the talk of Nashville for a year now. Singles have marched up the charts and fans have responded enthusiastically as McGraw debuted music on the road during his stadium tour with Kenny Chesney last year.

For the first time in years, everything is aligned exactly how McGraw wants it. And the 45-year-old singer is fired up like he's playing under Friday night lights.

That energy has translated to the people around him as well.

"I think a real cloud has been lifted," said Coran Capshaw, McGraw's manager since 2009. "He's got a great new partner in Big Machine and can put his music out and be in control of his career. The ability to move forward is here and that's been exciting. And that's where I think that energy comes from."

McGraw's final five years at Curb Records led to some discouraging low-wattage moments in what has otherwise been a mostly perfect two-decade career, and it's still not completely over. While a judge allowed McGraw to move forward with his recording career and sign with Big Machine, the legal fight drags on in court. And Curb continues to sell McGraw records, releasing a duets album just two weeks ago as McGraw was ramping up publicity for the Big Machine release.

The Louisiana native says it was often like that in the final years with Curb out of sync. McGraw remained a star during this period, stretching into acting and selling more records and tickets than most of his peers. But there's no question it was a stagnant period in which a series of best-of releases mixed in with new music led to confusion and frustration for fans.

It was even worse for McGraw, good friend Brad Warren said. To understand how difficult the period was for McGraw, the songwriter said, you have to understand how competitive the singer is.

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McGraw hits the road with 'Two Lanes of Freedom'

Safety as freedom

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The Delhi gang-rape of December 2012 brought to the streets the deep and growing concern about violence against women and the demand for women's safety. The movement is the voice of women reclaiming their right to safety and freedom, through resistance to all forms of patriarchal power and celebration of women's peaceful power and energy.

Commodification, appropriation and control over women's bodies and the resources of the earth are one aspect of the threat to safety. Imposition of hazardous technologies that we do not need is another aspect.

Safety has emerged as an overpowering concern - safety of women and children, tribals, farmers and rural communities, safety from nuclear hazard, and environmental as well as health hazards of GMOs. Across India, protests and movements are also growing about the safety of people's resources and wealth - their land, their forests, their rivers, their property - in the context of the violent resource grab that is the basis of the new "growth" economy.

There is a pattern in this continuum of violence and threats to life and safety, just as there is a pattern in the continuum of the struggles for the defence of life, safety and freedom. The exponential rise in concern for safety - reflected in the explosion of people's protests to stop violence against women, tribals, fishermen, peasants, the urban and rural poor and the violence against environment and life on earth - is a direct consequence of the dominant culture of greed and commodification.

Sadly, this culture is shrouded in the garb of neo-liberal paradigms of economics in which there is no life, no values, no ethics, no community, no society, no people, no justice, no place for equality, dignity and people's rights, no place for freedom and democracy, just money and markets.

These values do not stay insulated in a silo called "the economy". Through osmosis they become the dominant values of a society, shaping the culture (or, should we say, anti-culture?).

Nuclear safety

As 2012 came to a close and 2013 dawned, hundreds of people protesting the nuclear power plant at Koodankulam and demanding nuclear safety sang and danced together at the Idinthakarai coast, adjacent to the nuclear plant. The New Year celebrations breathed new life into the anti-nuclear struggle. The beach reverberated with the spirit of resistance, assertion, freedom and democracy.

The movement for nuclear safety is a movement for freedom - we do not need nuclear energy when the sun and wind are so generous; we do not need GMOs when biodiversity and ecological agriculture produces more, safer and better food.

For two years in a row, at his address to the Indian Science Congress, Prime Minister Manmohan Singh has tried to criminalise the citizen's movements for nuclear safety and biosafety. But his is not a lone voice. He is an echo of the structured money-making system that wants no breaks in its money-making, including the break that is necessary for ensuring safety. That is why he called for a "structured" debate onnuclear energy and GMOs, not a democratic debate.

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Safety as freedom

Freedom brings new challenges for Myanmar writers

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YANGON, Myanmar (AP) -- Poet Saw Wai parked himself on the lawn, unfurled a map of Myanmar with a blob of blood-red paint dripping down from a spot up north and invited people to make poetry with him.

"He's calling for more trouble," said a passerby.

What the message lacked in subtlety it made up for in brazenness. Government forces have been pounding ethnic rebels in Myanmar's northern Kachin state, displacing tens of thousands and testing the country's fast-growing friendship with the West. It's the sort of thing you couldn't really talk about here for 50 years.

___

EDITOR'S NOTE This story is the first installment in "Portraits of Change," a yearlong series by The Associated Press examining how the opening of Myanmar after decades of military rule is and is not changing life in the long-isolated Southeast Asian country.

___

Nearly two years into reformist President Thein Sein's term, the rush of hope and idealism that greeted many new freedoms most strikingly freedom of speech is turning into a measured assessment of the nation's progress. Long accustomed to writing around censorship, Myanmar's writers are relearning the habits of free thought and testing the boundaries of speech. But change has also brought questions about how licensing requirements and market capitalism will shape public debate and how speech should be regulated in a multiethnic and multireligious nation of Buddhists, Muslims and Christians.

Saw Wai, who served 28 months as a political prisoner, grinned as he handed out photocopies of his latest poems.

"I'm not afraid," he said. "I'm just a guinea pig, testing freedom of expression on behalf of the people."

Myanmar's censorship board, which shut in August, was officially rebranded the Copyrights and Registration Division at the end of January, just in time for Yangon's first international literary festival, where Saw Wai staged his poetry performance. The festival, which ended Sunday, brought together around 80 Myanmar authors including exiles and former political prisoners like opposition leader Aung San Suu Kyi and international writers, like Jung Chang, whose best-selling "Wild Swans" recently became available in Burmese, though it is still banned in China. Myanmar is also known as Burma.

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Freedom brings new challenges for Myanmar writers

REAL SHIT YOU ACTORS ARE DONE IM THE GREATEST OF ALL TIME CHARLIE ZELENOFF 32 0 CYBORG – Video

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REAL SHIT YOU ACTORS ARE DONE IM THE GREATEST OF ALL TIME CHARLIE ZELENOFF 32 0 CYBORG
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By: CHARLIE ZELENOFF

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REAL SHIT YOU ACTORS ARE DONE IM THE GREATEST OF ALL TIME CHARLIE ZELENOFF 32 0 CYBORG - Video

2012 Kia Forte 5-door Cyborg Edition – Video

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2012 Kia Forte 5-door Cyborg Edition
#8681; #8681; #8681; #8681;Please Look Below to Find Important Information #8681; #8681; #8681; #8681; ------------------------------------------------------------------------------------------ This is my personal Facebook Fan Page you will find daily updates, photos, and things you will not see on my Youtube Page. **My Facebook** http://www.facebook.com ------------------------------------------------------------------------------------------ If you live around Maryland, Virginia, or DC and want to come out to the events that I go to and see anything from Exotics to Supercars. Please visit this page. **carlovedc.com ** ------------------------------------------------------------------------------------------ This is a place where I upload random photos **Photos!** instagram.com --------------------------------------------------------------------------------------------

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Dana White: Cyborg vs. Ronda Rousey UFC Title Fight 'Has to Go to 135 Pounds'

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Stick a fork in it, folks. Negotiations for a UFC superfight between Ronda Rousey and Cristiane "Cyborg" Justino seem to be done for now.

Unfortunately, the two top-ranked female MMA fighters in the world haven't been able to agree on a set weight, as the massively-muscled Cyborg has continually states that a 140-pound limit is as low as she can physically go.

That's not good enough for UFC president Dana White.

White, a firm supporter of Rousey, recently confirmed to MMA Junkie that while he's still interested in making this fight happen, Cyborg likely won't be fighting for a title if Rousey meets her at a 140-pound catchweight:

It's not a title fight. If that's what [Cyborg] is willing to do is go to 140, let's let Ronda defend her title a few times and see if Ronda wants to go to 140. If I know Ronda, she probably would anyway, so let's see what happens. But if [Cyborg] wants to fight for a title and have a title fight, she has to go to 135 pounds.

A fight at 140 would be a fan fight because everybody wants to see it, but it's not one of those fights that makes sense.

White's stance effectively kills a superfight between Rousey and Cyborg, although, it remains to be seen if the Brazilian will attempt to cut down to the 135-pound bantamweight limit.

It may be possible, as White previously toldTATAMEthat famed MMA nutritionist Mike Dolce could possibly get Cyborg to trim the 10 pounds.

For her part, Cyborg and her trainer, Tito Ortiz, don't seem to like this turn of events.

Taking to Instagram in response to White's claims (via UFC Tonight)that Cyborg wanted "nothing" to do with Rousey, the former Strikeforce featherweight queen called her rival a "bitch,"challenging her to "step up" to 140 pounds.

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Dana White: Cyborg vs. Ronda Rousey UFC Title Fight 'Has to Go to 135 Pounds'