Malone’s Liberty Global Studies Spinoff of Latin American Unit

Liberty Global Plc (LBTYA), billionaire John Malones international cable-TV company, is studying the spinoff of its Latin American businesses.

The company is unable to predict when and if such a transaction would occur, according to a filing today. The spinoff would include Libertys VTR Internet and wireless businesses in Chile and its 60 percent stake in Liberty Cablevision of Puerto Rico.

Liberty Global has shifted its attention to Europe, where Malone is stockpiling cable assets to create a regional powerhouse. The company bought U.K. pay-TV provider Virgin Media Inc. last year for about $16 billion, and people with knowledge of the matter said last week the company is putting the final touches on an acquisition of Dutch broadband carrier Ziggo NV.

Latin America makes up about 10 percent of Liberty Globals sales and about 6 percent of its subscribers.

VTR plans to offer $1.4 billion in bonds today as it separates its debt holdings from the European business, London-based Liberty said in the filing.

To contact the reporter on this story: Crayton Harrison in New York at tharrison5@bloomberg.net

To contact the editor responsible for this story: Nick Turner at nturner7@bloomberg.net

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Malone’s Liberty Global Studies Spinoff of Latin American Unit

How the tea party undermines conservatism

One of the main problems with an unremittingly hostile view of government held by many associated with the tea party, libertarianism and constitutionalism is that it obscures and undermines the social contributions of a truly conservative vision of government.

Politics requires a guiding principle of public action. For popular liberalism, it is often the rule of good intentions: If it sounds good, do it. Social problems can be solved by compassionate, efficient regulation and bureaucratic management which is seldom efficient and invites unintended consequences in complex, unmanageable systems (say, the one-sixth of the U.S. economy devoted to health care). The signal light for government intervention is stuck on green.

For libertarians and their ideological relatives, the guiding principle is the maximization of individual liberty. It is a theory of government consisting mainly of limits and boundaries. The light is almost always red.

Conservatism offers a different principle of public action though a bit more difficult to explain than go or stop. In the traditional conservative view, individual liberty is ennobled and ordered within social institutions families, religious communities, neighborhoods, voluntary associations, local governments and nations. The success of individuals is tied to the health of these institutions, which prepare them for the responsible exercise of freedom and the duties of citizenship.

This is a limiting principle: Higher levels of government should show deference to private associations and local institutions. But this is also a guide to appropriate governmental action needed when local and private institutions are enervated or insufficient in scale to achieve the public good.

So conservatism is a governing vision that allows for a yellow light: careful, measured public interventions to encourage the health of civil society. There are no simple rules here. Some communities disproportionately affected by family breakdown, community chaos or damaging economic trends will need more active help. But government should, as the first resort, set the table for private action and private institutions creating a context in which civil society can flourish.

This goal has moral and cultural implications. Government has a necessary (if limited) role in reinforcing the social norms and expectations that make the work of civic institutions both possible and easier. Some forms of liberty say, the freedom to destroy oneself with hard drugs or to exploit men and women in the sex trade not only degrade human nature but damage and undermine families and communities and ultimately deprive the nation of competent, self-governing citizens.

But conservatives also need to take seriously the economic implications of this governing vision. Just as citizens must be prepared for the exercise of liberty, individuals must be given the skills and values human capital that will allow them to succeed in a free economy.

This is the essence of equal opportunity. But it is not a natural social condition. And many conservatives have failed to recognize the extent to which this defining American promise has been hollowed out.

Economic mobility is stalled for many poorer Americans, resulting in persistent, intergenerational inequality. This problem is more complex than an income gap. It involves wide disparities in parental time and investment, in community involvement and in academic accomplishment. These are traceable to a number of factors that defy easy ideological categorization, including the collapse of working-class families and the flight of decent blue-collar jobs.

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How the tea party undermines conservatism

A yellow light for government

WASHINGTON One of the main problems with an unremittingly hostile view of government held by many associated with the tea party, libertarianism and constitutionalism is that it obscures and undermines the social contributions of a truly conservative vision of government.

Politics requires a guiding principle of public action. For popular liberalism, it is often the rule of good intentions: If it sounds good, do it. Social problems can be solved by compassionate, efficient regulation and bureaucratic management which is seldom efficient and invites unintended consequences in complex, unmanageable systems (say, the one-sixth of the U.S. economy devoted to health care). The signal light for government intervention is stuck on green.

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A yellow light for government

Yolo County Libertarian Party awarding ‘Libery Scholarships’

The Libertarian Party of Yolo County will announce it Liberty Scholarship program at 7 p.m. Friday, Jan. 24, at the Spring Garden Restaurant, 610 Cottonwood Plaza, Woodland.

The program gives three $1,000 scholarships to Yolo County students for college. Members of the party will be hosting other county and city officials in addition to the press as they kick off this opportunity.

The Liberty Scholarship is a $1,000 scholarship offered by the Libertarian Party of Yolo County to encourage Yolo County students in their pursuit of higher education. These funds may be used by students to help pay the costs of tuition, books or other school expenses in one of Yolo County's institutions of higher learning or a nearby Sacramento college. It is offered to one graduating high school student, one community college student and one UC Davis student each year.

"The Libertarian way is a caring, people-centered approach to politics. We believe each individual is unique. We want a system that respects the individual and encourages us to discover the best within ourselves and develop our full potential," said party chairman Stephen Blakeman in a statement, "which is why we want to be part of the solution and reach out to those in our community who need some help getting started."

Scholarship applications will be accepted from Jan. 1 through March 31. Winning students will be notified by the Scholarship Committee of the LPYC by April 30.

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Yolo County Libertarian Party awarding 'Libery Scholarships'

Bikini Girls Play Games on Yacht in Greek Islands – New Reality TV Show – Video


Bikini Girls Play Games on Yacht in Greek Islands - New Reality TV Show
Promo for Nautical Channel TV series #39;Jump On Board: Sporades Islands #39; Nautical Channel #39;s hit reality TV series is back for more adventure on the high seas! ...

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Bikini Girls Play Games on Yacht in Greek Islands - New Reality TV Show - Video

A Conspiracy Against Obamacare: The Volokh Conspiracy and the Health Care Case – Video


A Conspiracy Against Obamacare: The Volokh Conspiracy and the Health Care Case
"A Conspiracy Against Obamacare" details how legal bloggers at the Volokh Conspiracy engaged in a spirited, erudite, and accessible discussion of the legal i...

By: The Heritage Foundation

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A Conspiracy Against Obamacare: The Volokh Conspiracy and the Health Care Case - Video

Cancer – who’s got it? Who won’t? News conference- cancer and alternative health care. – Video


Cancer - who #39;s got it? Who won #39;t? News conference- cancer and alternative health care.
"We are pleased to announce this nationwide educational campaign regarding how we Americans relate to cancer, and our health. HPS will be spearheading this n...

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Cancer - who's got it? Who won't? News conference- cancer and alternative health care. - Video

Health care website frustrates Spanish speakers- RUBIO: Why Sebelius, Congress should take ObamaCare bailout off the …

Many Latinos are being left out of the first wave of coverage under the new health insurance program because multiple glitches in the Spanish version of the website have made it difficult, or impossible, to enroll, experts say.

The site, CuidadoDeSalud.gov, launched more than two months late.

A Web page with Spanish instructions linked users to an English form.

And the translations were so clunky and full of grammatical mistakes that critics say they must have been computer-generated the name of the site itself can literally be read "be careful of health."

"When you get into the details of the plans, it's not all written in Spanish. It's written in Spanglish, so we end up having to translate it for them," said Adrian Madriz, a health care navigator who helps with enrollment in Miami.

The issues with the site underscore the halting efforts across the nation to get Spanish-speakers enrolled under the federal health care law. Critics say that as a result of various problems, including those related to the website, many people whom the law was designed to help have been left out of the first wave of coverage.

Slightly more than 30 percent of Latinos who number 53 million in the United States lack health care coverage. In surveys of Latino adults, a majority indicate support for the Affordable Care Act.

Federal officials say they have been working to make the site better and plan further improvements soon. Also, administrators say they welcome feedback and try to fix typos or other errors quickly.

"We launched consumer-friendly Spanish online enrollment tools on CuidadoDeSalud.gov in December which represents one more way for Latinos to enroll in Marketplace plans," said Health and Human Services Department spokesman Richard Olague in an email to The Associated Press. "Since the soft-launch, we continue to work closely with key stakeholders to get feedback in order to improve the experience for those consumers that use the website."

Still, efforts to enroll Spanish-speakers have fallen short in several states with large Hispanic populations, and critics say the translated version of HealthCare.gov could have helped boost those numbers.

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Health care website frustrates Spanish speakers- RUBIO: Why Sebelius, Congress should take ObamaCare bailout off the ...

Government’s Spanish health care website frustrates users

ALBUQUERQUE Mirroring problems with the federal health care website, people across the nation attempting to navigate the Spanish version have discovered their own set of difficulties.

The site, CuidadoDeSalud.gov, launched more than two months late. A Web page with Spanish instructions linked users to an English form.

And the translations were so clunky and full of grammatical mistakes that critics say they must have been computer-generated the name of the site itself can literally be read "for the caution of health."

"When you get into the details of the plans, it's not all written in Spanish. It's written in Spanglish, so we end up having to translate it for them," said Adrian Madriz, who helps with enrollment in Miami.

The issues with the site underscore the halting efforts across the nation to get Spanish-speakers enrolled under the federal health care law. Critics say that as a result of various problems, including those related to the website, many people whom the law was designed to help have been left out of the first wave of coverage.

Federal officials say they have been working to make the site better and plan further improvements. Also, administrators say they welcome feedback and try to fix typos or other errors quickly.

"We launched consumer-friendly Spanish online enrollment tools on CuidadoDeSalud.gov in December, which represents one more way for Latinos to enroll in Marketplace plans," Health and Human Services Department spokesman Richard Olague said in an e-mail. "Since the soft-launch, we continue to work closely with key stakeholders to get feedback in order to improve the experience for those consumers that use the website."

Still, efforts to enroll Spanish-speakers have fallen short in several states with large Latino populations, and critics say the translated version of healthcare.gov could have helped boost those numbers.

In California, officials have acknowledged the need for improvements, saying fewer than 5,500 people signed up for health care in Spanish in October and November, the most recent period for which records are available. About 4.3 million California residents speak only Spanish, according to census data.

In New Mexico, the state with the nation's highest percentage of Latino residents and where more than 20 percent of the state's population goes without health insurance, fewer than 1,000 people total signed up for coverage in October and November.

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Government's Spanish health care website frustrates users

Health care providers expected to ramp up hiring as reform takes hold

One things for sure when it comes to the impact of the Affordable Care Act: Health care and related industries are going to be on a hiring spree in the years to come to meet the demands of the law.

While critics say the law will cause companies to cut jobs or work hours so they will not be penalized for not offering health care coverage actions that are already under way, according to anecdotal reports other observers say the law will create scores of jobs.

Health care providers will need more nurse practitioners and physician assistants, and companies that are required to offer insurance to employees will need more human resources staffers to keep track of their compliance. Experts also expect more jobs for computer programmers and other information technology professionals, customer service representatives, insurance agents, and wellness and fitness coaches.

Susan Mesa, president of the job placement service AdvancedPractice.com, said the Affordable Care Act will only increase demand for nurse practitioners and physician assistants, who are already in demand because of a physician shortage and the growth of accountable care organizations, which are networks of doctors and hospitals that share responsibility for patient care to keep costs down.

Nurse practitioners and physician assistants are attractive options because they can do 75-85 percent of the work a physician does at 55 to 65 percent of the cost, Mesa told the Atlanta Journal-Constitution. Research has also shown that use of advanced practice practitioners can improve patient satisfaction and health care delivery efficiency.

According to the Obama administration, more than 2.1 million people have enrolled in private health insurance plans by signing up on new state and federal websites since they were launched in October. The federal site, HealthCare.gov, handles sign-ups for 36 states. The remaining 14 states and the District of Columbia have their own sites.

More insured people means an increase in the need for different types of health services, ranging from direct care to research and maintenance of medical records, Tony Lee, publisher of CareerCast.com, said in releasing a recent study on the need for more health care workers.

Last fall the Joint Center for Political and Economic Studies, in a forecast on minority hiring due to the Affordable Care Act, projected the health care industry overall could add a total of 4.6 million jobs in the next decade, a 31 percent increase from the current level. The group estimated a third of overall hiring could be the result of changes due to health care reform.

In addition to biomedical engineering positions, CareerCast says, the health care professions most in demand this year will be dental hygienists, occupational therapists, optometrists, physical therapists, chiropractors, speech pathologists, pharmacists, podiatrists, respiratory therapists and physician assistants.

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Health care providers expected to ramp up hiring as reform takes hold

Senior Staffers Strained by Health Care Changes

By Hannah Hess Roll Call Staff Jan. 13, 2014, 11:13 a.m.

The recent changes to health care benefits are taking their toll on senior-level staff morale on Capitol Hill, according to a new survey.

Nearly 4 in 10 chiefs of staff and district directors recently surveyed by the Congressional Management Foundation said they would likely be looking for a job outside the office within the next 12 months.

The elimination of staffs traditional health care has been a complete disaster, said one senior staffer, responding to the survey. If you wanted a legislative branch run by K Street lobbyists and 25-year-old staffers, Mission Accomplished.

CMF President and CEO Bradford Fitch said the nonpartisan nonprofit began receiving calls in April from Capitol Hill chiefs of staff who were concerned by the potential impact of the health care law, colloquially known as Obamacare, that mandated members of Congress and many members of their staff could no longer get health insurance through the Federal Employees Health Benefits Program beginning in 2014.

At the time, the Office of Personnel Management had not yet issued full guidelines for members and staffers who were required to gain coverage through the new health care exchanges, in order to continue receiving the governments employer contribution.

Calls began to build and build and build, Fitch said, and eventually the CMF was hearing about the issue on a daily basis. One 30-year veteran of the Hill feeling stressed by the health care changes even called and applied for a job at the CMF, Fitch said.

The CMF surveyed senior-level staff from Nov. 18 through Dec. 6, during the open enrollment period for staffers to register for coverage under the D.C. Small Business Health Options Program. Conclusions are based on 163 responses to 10 questions focused on staff benefits and office budgets.

Retaining staff and recruiting new talent were among the foremost concerns for chiefs of staff and district directors, with 79 percent predicting that changes to health care benefits could contribute to staffers leaving the office. Of those surveyed, 38 percent said it was likely that they would be looking for work outside the office in the next 12 months, and another 11 percent said they were unsure about the prospect of job-searching elsewhere.

I found out in September that I have breast cancer, one senior-level staffer responded. Im losing my health care coverage in the middle of my radiation treatment. Getting insured through the D.C. exchange is not helpful my choices are very limited and costs are high. As a result, Ive gone on my husbands plan. My staff dont necessarily have that option.

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Senior Staffers Strained by Health Care Changes

Testing times for the consumer genetics revolution

With the highest-profile seller of $99 genetic tests under fire, will public trust in personalised medicine suffer, an ethicist wonders

IT'S 2008. The New Yorker is chronicling a celebrity "spit party", at which notables nicknamed the "Spitterati" eject saliva into tubes to find out their risk of developing illnesses such as diabetes, heart disease and cancer. The firm involved is 23andMe, a direct-to-consumer genetic testing company whose service was named Invention of the Year by Time magazine.

Fast-forward five years. 23andMe receives a demand from the US Food and Drug Administration (FDA) to stop selling its health-related tests pending scientific analysis. In a separate event, a Californian woman, Lisa Casey, files a $5 million class action lawsuit alleging false and misleading advertising. 23andMe suspends sales of its test, putting paid to its target of reaching 1 million customers by the end of 2013. Where did it all go wrong?

In November, after what the FDA describes as years of "diligently working to help [23andMe] comply with regulatory requirements", the agency sent a scathing letter to the firm's CEO Anne Wojcicki. It stated that 23andMe's Personal Genome Service was marketed without approval and broke federal law, since six years after it began selling the kits, the firm still hasn't proved that they work.

Doubts go back a long way. In the year of the spit party, the American Society for Clinical Oncology commissioned a report that concluded the partial type of analysis involved wasn't clinically proven to be effective in cancer care. In 2010 the US Government Accountability Office concluded that "direct-to-consumer genetic tests [involve] misleading test results... further complicated by deceptive marketing".

What 23andMe offered was a $99 test for 250 genetically linked conditions, based on a partial reading of single-nucleotide polymorphisms (SNPs). These are points where the genomes of different individuals vary by a single DNA base pair. There are some 3 billion base pairs in the human genome this test targets only a fraction of them. Different companies sample different SNPs and so return different results for the same person.

To illustrate this point, in his book Experimental Man, science writer David Ewing Duncan recalled how he received three conflicting assessments of heart attack risk from three different companies. The director of one, deCODEme no longer offering such tests telephoned him from Iceland to urge him to start taking cholesterol-lowering statins. Yet the other two tests one from 23andMe, one from Navigenics, which no longer offers consumer tests had rated him at medium or low risk. Given that some statins carry side effects such as muscle weakness, Duncan might have been ill-advised to follow deCODE's urgent advice.

This is the root of the FDA's concerns. In its letter to 23andMe, it raised the risk that customers could get false information that leads to drastic and misguided medical steps. Wojcicki now says: "We want to work with [the FDA], and we will work with them." But is it too little, too late?

And what of the class action lawsuit, brought by Casey after buying a test? It focuses on the test's accuracy but goes further, targeting what Casey's attorney calls "a very thinly disguised way of getting people to pay [23andMe] to build a DNA database".

By asking customers to fill in surveys about health and lifestyle, 23andMe has been creating a valuable "biobank" for patenting purposes and industry collaboration. The firm has always sought customer consent for use of identifiable data and hasn't disguised its aim. "The long game here is not to make money selling kits, although the kits are essential to get the base level data," says 23andMe board member Patrick Chung. "Once you have the data, [23andMe]... becomes the Google of personalised healthcare."

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Testing times for the consumer genetics revolution

Multiple myeloma study uncovers genetic diversity within tumors

PUBLIC RELEASE DATE:

13-Jan-2014

Contact: Haley Bridger hbridger@broadinstitute.org 617-714-7968 Broad Institute of MIT and Harvard

The most comprehensive genetic study to date of the blood cancer multiple myeloma has revealed that the genetic landscape of the disease may be more complicated than previously thought. Through results published in Cancer Cell today, a team of Broad researchers has shown that an individual patient's tumor can harbor populations of cancer cells equipped with different mutations. These findings could have therapeutic implications for patients in the future.

"What this new work shows us is that when we treat an individual patient with multiple myeloma, it's possible that we're not just looking at one disease, but at many in the same person, there could be cancer cells with different genetic make-ups," said co-senior author Todd Golub, the Broad Institute's Chief Scientific Officer and Charles A. Dana Investigator in Human Cancer Genetics at the Dana-Farber Cancer Institute. Golub is also a professor at Harvard Medical School and an investigator at Howard Hughes Medical Institute. "These findings indicate a need to identify the extent of genetic diversity within a tumor as we move toward precision cancer medicine and genome-based diagnostics."

In a detailed study of samples from more than 200 multiple myeloma patients, Golub and colleagues identified frequent mutations in several key genes known to play an important role in cancer including KRAS, NRAS, and BRAF. But they found that many of these telltale mutations were not present in all cancer cells within a tumor instead, they were often found in only a smaller fraction of cells, known as a subclonal population.

Many promising cancer therapies used in treatment today target a specific genetic mutation. This new work suggests that such targeted therapies may have limitations in patients whose tumors are made up of these subclonal populations.

The research team performed follow-up experiments in the lab to explore some of the therapeutic implications, looking specifically at BRAF, a cancer gene for which several inhibitors, or drugs, exist. Previous studies indicated that around four percent of multiple myeloma patients may have mutations in this gene, and a recent report on a single multiple myeloma patient treated with drugs targeting BRAF showed promising results. BRAF inhibitors have also been used to treat patients with melanoma and other forms of cancer. In the lab, however, the research team found evidence that treating a tumor harboring subclonal BRAF mutations with one of these targeted drugs may at best kill a fraction of the cells, and at worst, stimulate another cancer cell subpopulation to grow.

"There's clearly potential for these drugs in some patients with multiple myeloma, but we show that there are also potential problems for others," said co-first author Jens Lohr an associated scientist at the Broad and a medical oncologist at Dana-Farber. "If a patient has a BRAF mutation in less than 100 percent of his cells, or if he has mutations in KRAS or NRAS at the same time, his oncologist would want to think through the potential pitfalls before giving the inhibitor."

Resistance or the ability for tumors to shrink and then grow back has become a major hurdle in treating patients with targeted therapies such as BRAF inhibitors. The new research suggests that subclonal populations could be one of the potential reasons many patients suffer relapse after treatment.

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Multiple myeloma study uncovers genetic diversity within tumors