Researchers measure minuscule particles with ‘tiny diving boards’

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Suspended nanochannel resonator (SNR), a high precision instrument, can now measure masses of particles as small as one millionth of a trillionth of a gram, say MIT researchers.

Researchers from MIT can now measure masses of particles as small as one millionth of a trillionth of a gram.

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The suspended nanochannel resonator (SNR), a high precision instrument devised by researchers, can determine the mass of particles with a resolution better than an attogram one millionth of a trillionth of a gram, according to a press release by the Massachusetts Institute of Technology.

With the help of the SNR, researchers can now determine the mass of minuscule-sized viruses, protein aggregates, and other naturally occurring and engineered nanoparticles (a nanometer is one-billionth of a meter), which were earlier difficult to measure due to their small size, according to the findings that were published in a paper for the Proceedings of the National Academy of Sciences.

Now we can weigh small viruses, extracellular vesicles, and most of the engineered nanoparticles that are being used for nanomedicine, said Selim Olcum, one of the paper's lead authors.

The SNR builds upon the suspended microchannel resonator (SMR), an earlier technology developed by Scott Manalis, an MIT professor of biological and mechanical engineering.

The SMR was used to track cell growth and measure density of cells, according to the MIT press release.

The SMR consists of a fluid-filled microchannel in a tiny silicon cantilever, a beam secured at one end. The particles are made to flow through the channel, one by one, and the mass of the particles changes the vibration frequency of the cantilever.

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Researchers measure minuscule particles with 'tiny diving boards'

Nobel Prize winner shuns ‘luxury journals’

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By Queena Lee-Chua Philippine Daily Inquirer

Last Dec. 10, Randy Wayne Schekman, an American cell biologist at the University of California, Berkeley, with James Rothman and Thomas Sdhof, accepted the 2013 Nobel Prize for Physiology.

The scientists were awarded for their work on machinery involving vesicle traffic, a major transport system in our cells.

But Schekman announced he would no longer be publishing in the most prestigious scientific journals in the world, such as Nature, Science and Cell, even though their publication of his papers was among the bases for his getting the Nobel.

Calling the publications luxury journals, Schekman accuses them of promoting the flashiest work, not the best.

He likens the publishing culture to that of Wall Street and says that just as huge undeserved bonuses damaged banking and finance, the prestige associated with publishing in luxury journals damaged the culture of research and science as a whole.

Like fashion designers who create limited-edition handbags or suits, [luxury journals] know scarcity stokes demand, so they artificially restrict the number of papers they accept, Schekman says in the British Guardian.

Schekman also says the so-called impact factor, the number of times research papers are cited in subsequent studies, is a deeply flawed measure.

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Anti-Aging Medicine

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Extend and expand your health and life span. Get more out of now and your future!

Anti-Aging Medicine

Both Anti-Aging medicine and current medical practice are attempting to increase life span and improve the quality of human life. Anti-Aging medicine tends to be more proactive and utilizes cutting edge approaches

As we age multiple hormone abnormalities develop and can be diagnosed clinically and through extensive lab work (evidence-based medicine). These abnormalities can cause weakness, fatigue, loss of libido, and decreased ambition and productivity. Growth hormone deficiencies are diagnosed through blood work. If there is a true deficiency, various natural supplements are prescribed (without injections) and subsequent clinical and lab reassessment is done.

Specific emphasis is placed on male and female menopause. Inwomen.natural therapeutics andbio-identical hormonesare used to increase the good estrogen and decrease the potentially carcinogenic (cancer-causing) bad estrogens. Inmen, clinical deficiencies in testosterone or its precursors or situations in which testosterone deficiencies arise from age-related conversion of testosterone to estrogen are treated with natural therapeutics. Only when all natural attempts to correct laboratory abnormalities have not obtained optimal results will other therapies will be utilized, eg. injections, gels, creams, etc.

Hormonal Causes of Aging Science has now documented that several important anabolic (body building type) hormones decrease in a predictable fashion,.

Bioidentical Hormonereplacement therapy (synthetic or nonsynthetic hormones that are identical in chemical structure to hormones produced naturally.) has many advantages such as:

(Wepfer, S. RPH, Int. J. Pharm. Compounding, vol. 5 No. 6, Dec 2001, pp 10-12)

Womans Health Initiative Study Why did a study on estrogen derived from pregnant horse urine and synthetic progesterone reveal negative results? Source: estrogen was derived from the urine of pregnant horses and included unnecessary forms of estrogen found only in horses. The progesterone utilized was a synthetic compound.

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Anti-Aging Medicine

Comets Split Weekend Series against Wave

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January 18, 2014 - Major Indoor Soccer League (MISL) Missouri Comets INDEPENDENCE, Missouri (January 18, 2013) - One night after giving the Milwaukee Wave their worst defeat in team history, the Missouri Comets were unable to duplicate the result. This time in Milwaukee's U.S. Cellular Arena, the Comets fell 16-4. Milwaukee's Jonathan Greenfield had two goals, one from three-point distance to lead his team to the win.

The Comets are statistically the best offensive team in the Major Indoor Soccer League. They have scored first and scored often in the majority of their games. Tonight, the Milwaukee Wave set out to slow down the high-powered Missouri attack. After setting in a defensive shell for the first fourteen minutes of the opening quarter, the Wave broke out and capitalized on a Comets mistake with Luan Oliviera scoring the game's first goal. Milwaukee's Jonathan Greenfield had two in the second quarter to put the Comets down 7-0 at the half.

The Comets offense could not be stifled all night however. Robert Palmer scored from the left side of the goal four minutes into the second half to get the Comets on the board. A minute later, Ramone Palmer stole the ball and dribbled up the left side of the field, drawing the Wave defense towards him before passing the ball to Stefan St. Louis for a tap-in goal. The score cut the Comets deficit to 7-4 and seemed to give the team life as they headed towards the final quarter.

Unfortunately for the Comets, the Milwaukee Wave restart was able to score two goals in the first three minutes of the fourth quarter. Nicolas Perera and Ian Bennett scored to increase the Wave lead to 11-4.

Soon after, in a bizarre series of events, Comets goalkeeper Danny Waltman was issued two blue cards and faced a shootout and penalty kick. Waltman had been playing aggressive all night, as he pressed forward his shot was blocked and the Wave had an open path to goal. Waltman reached out to block the ball at midfield and was issued his first blue card. On the ensuing shootout attempt, Waltman came out of the box and tripped Guiliano Oliviero; earning his second blue card. Now with two players in the penalty box serving time, Waltman was unable stop the penalty kick.

As the Comets put in a sixth attacker, Ian Bennett broke the Missouri attack and added a three-point empty net goal to clinch the Wave's win.

The Comets will return home to the Independence Events Center next Friday, January 24th at 7:35p.m. CT to take on the St. Louis Ambush. The Comets will be hosting their Annual Retro Night and will be honoring players of the Comets/Attack history. The team will be wearing special jerseys and auctioning them off following the game.

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Comets Split Weekend Series against Wave

Comets roughed up again in sixth straight AHL setback

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UTICA The Utica Comets dropped their most lopsided decision of the season on Friday night, going down to an 8-3 defeat against the Albany Devils.

Despite a sold-out Utica Memorial Auditorium, the Comets were unable to put together a complete performance and lost their sixth consecutive game in a row.

Benn Ferriero, Alexandre Grenier and Brandon DeFazio scored for Utica in a losing effort. Goaltenders Mathieu Corbeil and Joe Cannata each surrendered four goals for the Comets, who fell to 11-20-2-3 with the defeat.

Rome native and Devils center Tim Sestito finished with an assist and racked up a 2-minute hooking penalty in the third period.

The 29-year-old Sestito has accounted for six goals and 10 assists in 25 games played this season.

Albany, which improved to 22-11-3-2 overall, scored two goals in the opening frame and four more in the second period to take a commanding 6-1 lead.

Goals came off the sticks of Mattias Tedenby, Rod Pelley, Kelly Zajac, Harri Pesonen, Mike Sislo, Mike Hoeffel, and a pair of goals by Joe Whitney.

Devils netminder Keith Kinkaid also stopped 31 of 34 shots in between the pipes.

The Comets will have to regroup quickly as they travel to Hamilton for a matchup with the Bulldogs this evening. Puck drop is set from Copps Coliseum at 7 p.m.

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Comets roughed up again in sixth straight AHL setback

Gameday: Comets at Hamilton

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January 18, 2014 - American Hockey League (AHL) Utica Comets UTICA COMETS (11-20-2-3) @ HAMILTON BULLDOGS (19-15-0-4)

Copps Coliseum, 7 p.m.

Radio: 94.9 K-Rock

Tonight's Game: The Utica Comets look to snap a six game losing skid as they travel north to take on the Hamilton Bulldogs. The Comets are currently in the midst of their second losing streak of five of more games this season.

When They Last Met: Utica and Hamilton played a thriller at The AUD in late November, which resulted in a 4-3 shootout victory for the Bulldogs. Henrik Tommernes scored with 1:04 left in regulation to force the extra session, while Alexandre Grenier and Darren Archibald also found the back of the net for the Comets. Nathen Beaulieu ended things with the game winning goal in the sixth round of the shootout.

Comets Outlook: The Utica Comets will being seeing red for quite some time, after they dropped their most lopsided decision of the season, an 8-3 defeat against the Albany Devils. Benn Ferriero, Alexandre Grenier and Brandon DeFazio scored for Utica in a losing effort. Goaltenders Mathieu Corbeil and Joe Cannata each surrendered four goals for the Comets, who fell to 11-20-2-3 with the defeat.

Bulldogs Outlook: Hamilton returns to action for the first time since Sunday, Jan. 12, where they defeated the Iowa Wild, 3-1. Nathan Beaulieu led the Bulldogs with two points (1-1-2) and Gabriel Dumont and Nick Tarnasky also scored for Hamilton.

Winger Marc Hagel was the lone goalscorer for Iowa, with a second period power-play marker. Dustin Tokarski earned his 15th victory of the season with 28 saves on 29 shots.

Not So Great Eight: The Utica Comets were on the wrong side of history against Albany, as their eight goals surrendered set a franchise high for goals allowed. The five goal margin of defeat was also a team worst. With the exception of wingers Alex Grenier and David Marshall and defensemen Alex Biega and Peter Andersson, all other 14 Comet skaters had a negative rating for the evening.

The Grass Is Always Grenier: Winger Alex Grenier extended his team high in goals to 12 for the season, with a third period marker against the Albany Devils. The Laval, PQ native is now tied for 12th in the AHL in rookie scoring with 24 points (12-12-24) this season.

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Gameday: Comets at Hamilton

Clayton boys stay on championship course, top Southeast Raleigh

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CLAYTON During a late fourth quarter timeout, Clayton boys basketball coach Denny Medlin was talking about more than just protecting the Comets five-point lead.

He was telling his team about winning a championship.

Aided by a stellar night from the free throw line, Clayton staved off a pesky Southeast Raleigh team 64-54 Friday to keep its stranglehold atop the Greater Neuse River 4A Conference. For Medlin and the Comets, Fridays game was just another piece of a bigger puzzle.

We talk about how every game is for the conference championship, Medlin said. I wanted to remind them that its not okay to let this one slip through. We had the lead and there wasnt much time left so I just wanted to remind them that its not okay to let it go.

What Worked: Theres one statistic that jumps off the page from this game: Clayton shot 33-for-38 from the free throw line. Southeast Raleigh? Just 1-for-1. By the time the Bulldogs (9-6, 3-4) shot their first and only foul shot of the game with 4:48 left in the fourth quarter -- the Comets had already hoisted up 22 of their own.

Southeast is a very physical team and I thought we were really disciplined, Medlin said. We got the kind of shots that we wanted in the paint; we werent settling for jumpers. We were pretty successful keeping the ball out of the paint defensively whereas on the other end we were trying to get the ball as deep as we can.

Not only was Clayton getting to the free throw line, the Comets were taking advantage once there. Clayton made its first 19 foul shots of the game and Gary Clark led the effort by sinking 18 of his 20.

Weve got such a good shooting team that theres no reason we shouldnt be a good free throw shooting team. Its something we emphasize more, Medlin said. Theres been games where weve shot it well but then we didnt shoot free throws well in our losses.

Turning Point: Clayton watched a 12-point halftime lead all but evaporate in the third quarter and with 1:07 remaining in the game the Comets led just 57-54. But Clayton closed things out at the foul line where else by making five of six bonus free throws in the final minute.

Putting Up Numbers: Clark scored 32 points to lead all scorers, while the Bulldogs Demetrius Sanders accounted for 26 points. Tre Armstead added nine points for Clayton.

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Clayton boys stay on championship course, top Southeast Raleigh

Ferriero scores twice to lead Comets over Bulldogs

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HAMILTON, Ont. -- The Hamilton Bulldogs stressed the need for a strong start before Saturday's game, but the reality on the ice didn't go as planned. Instead, the Utica Comets scored twice in the first period and the Bulldogs never dug out of the early hole.

Benn Ferriero scored twice and Joe Cannata made 32 saves as the Comets defeated the Bulldogs 3-1 in the American Hockey League on Saturday.

"Our first point before the game was that we needed a good start," said Hamilton head coach Sylvain Lefebvre. "They scored two goals early in the first and then we found ourselves battling through adversity and trying to play catch-up.

"We just didn't have it tonight. All-in-all, we just weren't sharp and we couldn't make things work."

Alexandre Grenier also scored for the Comets (12-20-5), who snapped a six-game losing streak with the victory. Comets leading scorer Pascal Pelletier had three assists to increase his point total to 11 in his past eight games.

Maxime Macenauer scored the lone goal for the Bulldogs (19-15-4), while Dustin Tokarski stopped 31 shots.

Sven Andrighetto had a chance to score for Hamilton three minutes into the game, but the Bulldogs' winger could not get his stick on the cross-ice pass from linemate Martin St. Pierre.

The Bulldogs had possibly their best scoring chance of the first period when Justin Courtnall sprung a short-handed rush with Greg Pateryn in the box for tripping. The winger's initial shot was stopped by Cannata, with Patrick Holland unsuccessfully jamming at the loose rebound.

Utica opened the scoring with what looked like a harmless shot from Ferriero at 11:21. After waiting for a thick screen to develop in front of Tokarski, Peter Andersson released a slow, rising wrist shot that tipped off both Pelletier and Ferriero before beating the goaltender, who didn't see the puck until the last moment.

The Comets doubled their advantage through an almost identical move on the power play at 13:42 when Henrik Tommernes fired a high slap shot that deflected off Grenier in front, and beat the goaltender over the blocking glove at the far post.

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Ferriero scores twice to lead Comets over Bulldogs

Psoriasis – Medscape Reference

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Psoriasis - Medscape Reference