2014 Louis-Jeantet Prize for Medicine

PUBLIC RELEASE DATE:

21-Jan-2014

Contact: Carole Liernur liernur@jeantet.ch 41-227-043-631 European Molecular Biology Organization

The 2014 LOUIS-JEANTET PRIZE FOR MEDICINE is awarded to the Italian biochemist Elena Conti, Director of the Department of Structural Cell Biology at the Max-Planck Institute of Biochemistry in Munich (Germany) and to Denis Le Bihan, the French medical doctor, physicist and Director of NeuroSpin, an institute at the French Nuclear and Renewable Energy Commission (CEA) at Saclay near Paris.

The LOUIS-JEANTET FOUNDATION grants the sum of CHF 700'000 for each of the two 2014 prizes, of which CHF 625'000 is for the continuation of the prize-winner's work and CHF 75'000 for their personal use.

THE PRIZE-WINNERS are conducting fundamental biological research which is expected to be of considerable significance for medicine.

ELENA CONTI is awarded the 2014 Louis-Jeantet Prize for Medicine for her important contributions to understanding the mechanisms governing ribonucleic acid (RNA) quality, transport and degradation.

In order to function properly, our cells need to degrade macromolecules that are faulty or no longer needed. The biochemist deciphered at the level of atomic resolution how faulty RNAs are recognized and eliminated. Notably, her group deciphered the three-dimensional architecture and molecular mechanisms of the exosome, a multiprotein complex that recognizes and degrades RNAs. The work revealed that several principles of the mechanism of this essential nano-machine are conserved in different forms of life.

Elena Conti will use the prize money to conduct further research into the structure and regulation of the exosome.

DENIS LE BIHAN is awarded the 2014 Louis-Jeantet Prize for Medicine for the development of a new imaging method that has revolutionized the diagnosis and treatment of strokes.

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2014 Louis-Jeantet Prize for Medicine

Make Your Voice Heard During FFM 2.0 Virtual Town Hall

As family medicine continues the process of examining the challenges and opportunities that face the specialty today and defining a path forward in the context of a rapidly changing health care landscape, your voice is keenly important. An upcoming series of virtual town hall meetings being convened as part of the Family Medicine for America's Health: Future of Family Medicine 2.0 (FFM 2.0) project will give you a chance to add your voice to this crucial discussion.

The first of those virtual town hall events is scheduled for Jan. 29 from 8-9 p.m. EST, and practicing family physicians from across the country are invited to participate.

Led by AAFP Past President Glen Stream, M.D., M.B.I., of La Quinta, Calif., the group will discuss family physician responses to the question: What are the three issues that will be most critical to address in the strategic plan so that family medicine can achieve the triple aim of better health, better care and lower costs?

As was the first Future of Family Medicine project that launched more than a decade ago, FFM 2.0 is an effort of the Family Medicine Working Party, which consists of the following organizations:

The groups already have made significant progress in considering a number of key questions facing the specialty today:

Read more about the progress the project has made to date in updates published last year in September, October and December.

The research and planning phase of the FFM 2.0 project is expected to be completed by April, and then work begins to implement a five-year, action-oriented strategic plan that addresses the issues most critical to family medicine and provides a role for the seven family medicine organizations. The project also will include a family medicine communications platform that aligns with stakeholders' expectations, perceptions and emotional attachments, along with a plan to communicate the value and benefits of family medicine.

Don't miss this opportunity to play a role in making all that happen. Those who wish to participate in the Jan. 29 virtual town hall event can register online(transformed.adobeconnect.com).

Two additional meetings will be held in late February and March, although precise dates and times are yet to be determined. Each meeting will be recorded and archived and can be accessed from the AAFP website.

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Make Your Voice Heard During FFM 2.0 Virtual Town Hall

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Turn to Current Students When Choosing a Medical School

Students visiting a medical school should ask current M.D. candidates about the curriculum and how stressed they are.

Finding the right medical school is a two-way street. While students have to persuade admissions officers of their worth, an institution has to sell itself, too. One way to gauge whether a school is the right fit: campus visits.

Medical school campus visits are often part of the admissions process. A number of schools interview applicants for much of the school year, sometimes hosting two candidates every week from September through March. Hopeful M.D.s usually spend the day getting a tour of the campus, sitting in on a class, interviewing with a faculty member and eating lunch with current students.

[Find a postbaccalaureate premed program that fits you.]

At some schools, interested candidates that have yet to apply such as those in a premed society also tour campus and meet with admissions officers, but aspiring students vying for an acceptance letter are much more common.

Experts agree that one of the most important things prospective medical school students can do during a visit is speak with current students. They, more than other people at a school, can give the most candid perspective on student life.

"They obviously really have some inside information that could be very valuable," says Sherri Baker, a pediatric cardiologist and the associate dean for admissions at the University of Oklahoma College of Medicine.

Schools often have current students give tours and eat lunch with prospective students. Admissions experts say it's during those times that a prospective candidate should ask questions about how and what medical students are taught.

They can ask about what the relationship is like between students and faculty and what kind of teaching methods are used, suggests Stephen Wheeler, an associate professor of family and geriatric medicine and associate dean of medical school admissions at the School of Medicine at University of Louisville. He says students can use these conversations to find out if a school practices team-based learning or other methods.

[Smarten up about medical school success.]

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Turn to Current Students When Choosing a Medical School

Dean named for UT med school

AUSTIN (AP) The University of Texas has named a dean for its medical school, the first to be established by a tier-one university in decades, according to a published report.

Clay Johnston will assume his new role as head of UTs Dell Medical School on March 1. The 49-year-old Johnston currently is associate vice chancellor of research for the University of California, San Francisco considered one of the nations leading health science centers.

Johnston will oversee construction, hiring, curriculum development, admissions and other matters that must be concluded before the Dell school enrolls its first students in fall 2016, the Austin American-Statesman reported (http://bit.ly/1aJitXP ). Fifty students will be admitted annually for at least the first four years.

Johnston said it will take 20 years for the school to achieve broad excellence and prominence. He told the American-Statesman that he was drawn to Austin by the prospect of leading a medical school unconstrained by tradition and habit.

It just opens all kinds of opportunities to do it right. Im very excited to move to a new platform and create a medical school that looks like one for the new century rather than the last century, he said. And I hope we train more primary care docs than specialists.

Johnston will be paid $675,000 in his new role. The man who introduced him at a news conference Tuesday, UT President Bill Powers, is paid $624,350 a year.

Johnston said he envisions the Dell school adopting an approach in which pharmacists, nurses and other health care workers, not just doctors, are integral parts of the mix. Also being planned are a new teaching hospital, research and education buildings, and an approach to caring for indigent patients that officials say promises to improve their health while cutting costs.

UT administrators will be pushing for students to learn many of their lessons independently or in small groups, with less class time devoted to lectures and more time available for discussions and problem-solving.

Seton Healthcare Family has agreed to build, own and operate a $295 million teaching hospital on university-owned land adjacent to where UT will construct a research building, a medical office building and an education and administration building. UTs governing board has committed $25 million a year and an additional $5 million for the first eight years. The Travis County health care district has pledged to channel $35 million a year from a voter-approved property tax increase to the medical school.

We now have a world-class dean to lead a world-class medical school, said state Sen. Kirk Watson, D-Austin, who has been a leader in efforts to establish the school.

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Dean named for UT med school

HMS receives RPB Medical Student Eye Research Fellowship

PUBLIC RELEASE DATE:

22-Jan-2014

Contact: Mary Leach Mary_Leach@meei.harvard.edu 617-573-4170 Massachusetts Eye and Ear Infirmary

Boston (January 22, 2014) The Harvard Medical School (HMS) Department of Ophthalmology has been granted a $30,000 Research to Prevent Blindness (RPB) Medical Student Eye Research Fellowship for Christina Marsica Grassi.

This grant will enable Ms. Grassi to take year-long sabbatical from medical school to pursue a research project within the Massachusetts Eye and Ear and HMS Department of Ophthalmology. Ms. Grassi will work with Dr. James Chodosh in the Howe Laboratory's Viral Pathogenesis Unit at Mass. Eye and Ear.

"The goal of Ms. Grassi's project is to elucidate the mechanisms that trigger the development of sterile vitritis in patients who have received an artificial Boston Keratoprosthesis (KPro) implant. These studies also may enrich our understanding of immune responses to other indwelling prosthetic devices," said Joan W. Miller, M.D., F.A.R.V.O., Chief of Ophthalmology at Mass. Eye and Ear and Massachusetts General Hospital and Chair of the HMS Department of Ophthalmology.

For patients who have failed corneal allograft surgery or are poor candidates for corneal transplantation, the damaged cornea can be replaced with a keratoprosthesis, or an artificial cornea, but post-operative inflammation remains a problem for many patients. A poorly characterized, idiopathic inflammation of the vitreous humor, called sterile vitritis, is one manifestation of inflammation after KPro implantation, Dr. Miller explained. The RPB Fellowship Grant will enable Ms. Grassi to conduct research that may lead to a better understanding of the underlying mechanisms that control this process and, ultimately, help refine the technology and improve outcomes for patients with this condition.

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About Mass. Eye and Ear

Mass. Eye and Ear clinicians and scientists are driven by a mission to find cures for blindness, deafness and diseases of the head and neck. After uniting with Schepens Eye Research Institute in 2011, Mass. Eye and Ear in Boston became the world's largest vision and hearing research center, offering hope and healing to patients everywhere through discovery and innovation. Mass. Eye and Ear is a Harvard Medical School teaching hospital and trains future medical leaders in ophthalmology and otolaryngology, through residency as well as clinical and research fellowships. Internationally acclaimed since its founding in 1824, Mass. Eye and Ear employs full-time, board-certified physicians who offer high-quality and affordable specialty care that ranges from the routine to the very complex. U.S. News & World Report's "Best Hospitals Survey" has consistently ranked the Mass. Eye and Ear Departments of Otolaryngology and Ophthalmology as among the top hospitals in the nation. For more information about life-changing care and research, or to learn how you can help, please visit MassEyeAndEar.org.

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HMS receives RPB Medical Student Eye Research Fellowship

Mass. Eye and Ear physician awarded RPB Career Development Award

PUBLIC RELEASE DATE:

22-Jan-2014

Contact: Mary Leach Mary_Leach@meei.harvard.edu 617-573-4170 Massachusetts Eye and Ear Infirmary

Boston (Jan. 22, 2014) The Harvard Medical School (HMS) Department of Ophthalmology has been granted a $250,000 Research to Prevent Blindness (RPB) Career Development Award to support eye research conducted by Jason I. Comander, M.D., Ph.D. The support will be provided over a four-year period.

The RPB Career Development Award Fund was established in 1990 to attract young physicians and basic scientists to eye research. To date, the program has given awards to 174 vision research scientists in departments of ophthalmology at universities across the country.

Dr. Comander's current research efforts are focused on studying patients with inherited retinal degenerations, including retinitis pigmentosa (RP), which is caused by genetic mutations inherited from one or both parents. Most people who suffer from RP typically experience a steady visual decline during their lifetime, with many patients becoming blind. The disease affects approximately 100,000 people in the U.S. and 2 million people worldwide.

A clinician scientist, Dr. Comander is a member of the Retina Service and the Berman-Gund Laboratory for the Study of Retinal Degenerations at Mass. Eye and Ear. He also conducts research as a member of the Ocular Genomics Institute at Mass. Eye and Ear/Harvard Medical School. With support from the RPB grant, Dr. Comander intends to develop and apply techniques for high-throughput functional characterization of human genetic variation and mutation in retinitis pigmentosa.

"This research addresses a major challenge in understanding the mechanisms that underlie the pathology of inherited retinal disease, and will help us determine which gene misspellings in patients are disease-causing and which are benign," says Dr. Comander. "This is an important time in the field of inherited retinal degenerations, when early successes with gene therapy and molecular diagnostics need to be expanded and translated into broad clinical use."

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About Mass. Eye and Ear

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Mass. Eye and Ear physician awarded RPB Career Development Award