Cell Physiology Drama
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Cell Physiology Drama - Video
St Mary’s MSc Applied Sport and Exercise Physiology Postgraduate Programme – Video
St Mary #39;s MSc Applied Sport and Exercise Physiology Postgraduate Programme
Hear from St Mary #39;s University students on the MSc Applied Sport and Exercise Physiology postgraduate programme. Part of the School of Sport, Health and Appl...
By: St Mary #39;s University, Twickenham
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St Mary's MSc Applied Sport and Exercise Physiology Postgraduate Programme - Video
Physiology of Memory (Part 6) – Video
Physiology of Memory (Part 6)
The role of PKM zeta, part 1.
By: Brian Kurilla
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Physiology of Memory (Part 6) - Video
A systematic survey of lipids across mouse tissues …
Lipids are a diverse collection of macromolecules essential for normal physiology, but the tissue distribution and function for many individual lipid species remain unclear. Here, we report a mass spectrometry survey of lipid abundance across 18 mouse tissues, detecting ~1,000 mass spectrometry features, of which we identify 179 lipids from the glycerolipids, glycerophospholipids, lysophospholipids, acylcarnitines, sphingolipids and cholesteryl ester classes. Our data reveals tissue-specific organization of lipids and can be used to generate testable hypotheses. For example, our data indicates that circulating triglycerides positively and negatively associated with future diabetes in humans are enriched in mouse adipose tissue and liver, respectively, raising hypotheses regarding the tissue origins of these diabetes-associated lipids. We also integrate our tissue lipid data with gene expression profiles to predict a number of substrates of lipid-metabolizing enzymes, highlighting choline phosphotransferases and sterol O-acyltransferases. Finally, we identify several tissue-specific lipids not present in plasma under normal conditions that may be of interest as biomarkers of tissue injury, and show that two of these lipids are released into blood following ischemic brain injury in mice. This resource complements existing compendia of tissue gene expression and may be useful for integrative physiology and lipid biology.
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A systematic survey of lipids across mouse tissues ...
Sex Cells
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Newswise BIRMINGHAM, Ala. The idea that sex sells is generally accepted as fact. The idea that the sex of cells is important to biomedical research is not as well-known, but an article co-written by a researcher at the University of Alabama at Birmingham, suggests that the sex of individual cells matters.
The sex of a cell is determined by the presence of sex chromosomes: every cell can be categorized as either male or female. The significance of a cells sex is a concept that has been generally overlooked by the research community, but there is now a growing body of evidence that has some researchers examining important implications.
Male cells have an X and a Y chromosome, while female cells have two X chromosomes, said Cathy Fuller, Ph.D., associate professor in the Department of Cell, Developmental and Integrative Biology at UAB. There is now good reason to consider that studies conducted in male cells will produce results different from those of identical studies using female cell lines. This could have a profound effect on fields such as personalized medicine.
This month, Fuller, along with colleague Paul Insel, Ph.D., of the departments of Pharmacology and Medicine at the University of California-San Diego, published an editorial in the American Journal of Physiology-Cell Physiology called I Dont Know the Question, but Sex is Definitely the Answer! The editorial comes on the heels of a 2012 decision by the American Physiology Society to require authors to report the sex of the cells lines, biological materials and animals used in their experiments.
Fuller and Insel looked at two articles published in AJP-Cell and one in Nature that laid out the reasons that the APS decision to disclose the sex of cell lines was essential. They wrote that the lessons learned from these articles suggest the APS policy could have an important effect on patient care.
We have assumed that cells bearing an XY genotype behave the same as cells that are XX, but we dont really know if that is correct, said Fuller. Do T-84 cells, derived from a male colon cancer patient, behave the same as Ht-29 colon cancer cells, derived from a female? And will a colon cancer drug tested in one cell line work in the same fashion in all patients?
An additional complication, according to Fuller, is that many cell lines frequently used in research are old some have been around for more than 50 years and some supposedly male lines have lost the Y chromosome through the many repetitive cell culture cycles.
As we move closer to the concept of personalized medicine, where drugs and therapies can be tailored for the individual patient, we will need a more complete understanding of the physiology of that patient down to the cellular level, Fuller said. A drug that was tested in a cell line without a Y chromosome might not work as well in a patient who does have Y chromosomes. This could help explain why certain drugs work better in some patients than in others. Fuller says investigators working on developing drugs such as small molecules and biologics will need to consider that sex differences may underlie differences in responsiveness of different cells used in high-throughput screens, as well as considering the sex of the patient group to whom the drugs are targeted. Sex differences will be particularly important in stem cell-based therapies, such that the sex of both the donor and the recipient should be considered. She also suspects that other scientific journals will follow suit and require investigators to identify the sex of their cell lines. The good news is that the sex of many of the major cell lines currently in use is known and that information is available to researchers. About UAB Known for its innovative and interdisciplinary approach to education at both the graduate and undergraduate levels, the University of Alabama at Birmingham is an internationally renowned research university and academic medical center and the state of Alabamas largest employer, with some 23,000 employees and an economic impact exceeding $5 billion annually on the state. The five pillars of UABs mission deliver knowledge that will change your world: the education of students, who are exposed to multidisciplinary learning and a new world of diversity; research, the creation of new knowledge; patient care, the outcome of bench-to-bedside translational knowledge; service to the community at home and around the globe, from free clinics in local neighborhoods to the transformational experience of the arts; and the economic development of Birmingham and Alabama. Learn more at http://www.uab.edu.
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Sex Cells
Matthew Goodwin – "New Vistas in Emotion and Technology" – Video
Matthew Goodwin - "New Vistas in Emotion and Technology"
Matthew Goodwin, an Assistant Professor in the Department of Health Sciences and the Department of Computer Information Science at Northeastern University,...
By: NortheasternCOS
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Matthew Goodwin - "New Vistas in Emotion and Technology" - Video
Anti Aging Medicine | Weight Loss Clinic | Bardisa Medical …
Home We live in a time where medicine is changing. There are constant struggles between what we as doctors and patients feel we need to better our health, and what our insurance companies actually enable us to do. As your doctor, I am constantly in the fore front of learning what we can do to not only cure a disease, but prevent it all together. The future is here. Preventative medicine is the key. Through an additional board certification in anti-aging medicine, I have compiled a complete line of state of the art tests, supplements, and treatment to keep you a step ahead in the road to wellness. My goal with all of my patients is simple, Be proactive not reactive. Through dietary revision, and by improving our detoxification capacities, we can ultimately minimize drug therapy. This will ultimately improve your energy, state of well being, and keep you living younger longer. Dr. Roselind H. Bardisa is board certified in Family Medicine. She has been practicing medicine for over 15 years and specializes in preventative medicine, nutrition and fitness. She is a diplomat of the prestigious American Academy of Anti-Aging medicine. The A4M is dedicated to the advancement of technology to detect, prevent, and to promote research into methods to hinder and optimize the human aging process.
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Anti Aging Medicine | Weight Loss Clinic | Bardisa Medical ...
City of Hope Researcher Receives Five Grants Totaling $450,000 to Fight Pediatric Brain Tumors
Released: 2/11/2014 6:00 PM EST Source Newsroom: City of Hope Contact Information
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Newswise DUARTE, Calif. Despite continual advances in the treatment of brain tumors, infants and children diagnosed with medulloblastoma a fast-growing tumor in the cerebellum portion of the brain still face significant challenges overcoming this disease. One particularly tricky obstacle is the blood-brain barrier, which prevents cancer drugs from passing into the brain and attacking the tumor. Margarita Gutova, M.D., an assistant research professor in City of Hopes Department of Neurosciences, may have found a way to bypass that hurdle using neural stem cells.
Neural stem cells offer a novel way to overcome this obstacle because they can cross the blood-brain-barrier, migrate to and selectively target tumor cells throughout the brain, Gutova said. The cells also can be engineered to help deliver anti-cancer agents directly to the tumor site, effectively targeting cancer cells while minimizing harm to surrounding normal tissue.
Five foundations Alexs Lemonade Stand Foundation, Pediatric Cancer Research Foundation (PCRF), The Matthew Larson Foundation for Pediatric Brain Tumors and two anonymous foundations have announced grants totaling $450,000 in support of Gutovas work, allowing her to continue her preclinical studies of this novel treatment method. If additional research proves promising, human clinical trials could begin in three to five years, Gutova said.
Ultimately, Gutova hopes to develop neural stem cells into a potent and highly targeted therapy that is superior to current medulloblastoma treatments: surgery, radiation and chemotherapy. Surgery can leave behind residual cancerous cells that will continue to grow after the procedure, and radiation and chemotherapy can affect normal brain tissue.
This is especially damaging to brain and skeletal development, especially for pediatric patients still-growing bodies, Gutova said of current treatments.
In addition to testing the efficacy of neural stem cell-mediated therapy, Gutova will study the intranasal administration of neural stem cells. This novel delivery method is non-invasive and, if proven effective, will reduce the number of complicated procedures and their associated risks that a patient has to endure.
When the traditional treatment protocol failed for my daughter Alex, clinical trials became our best and only option for combating her cancer, said Jay Scott, co-executive director of Alexs Lemonade Stand Foundation. We know firsthand how important these trials are to bettering the lives of childhood cancer patients, and we are dedicated to bringing promising research from the lab to the clinic. We see promise in Dr. Gutovas brain tumor research and are glad to be able to support her efforts.
We are proud to support City of Hope and Dr. Gutovas research. City of Hope is a leader in making a difference every day in the laboratory, clinics and the lives or our young patients, said, Jeri Wilson, executive director of PCRF. I know Dr. Gutova and her colleagues will strive every day to ensure their research delivers the best possible outcomes to families who so richly deserve a cure.
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City of Hope Researcher Receives Five Grants Totaling $450,000 to Fight Pediatric Brain Tumors
Seven days: 713 February 2014
Research | Events | Policy | People | Facilities | Business | Trend watch | Journalism grant | Coming up
Cancer genomics Tumour genome sequencing may identify targeted treatments for only a fraction of patients with advanced breast cancer, according to research published on 7February (F.Andr etal. Lancet Oncol. http://doi.org/rdh; 2014). Of 423 people studied, the authors identified only 13% with mutations that matched an available experimental treatment. The rate of successful therapy-matching falls short of claims from some tumour-sequencing companies, but researchers expect odds to improve as more drugs move into clinical trials.
Sharing drug data Ten major pharmaceutical companies have agreed to share data from early-stage trials with each other and with academic researcher, as part of a US$230-million venture with the US National Institutes of Health. The Accelerating Medicines Partnership, announced on 4February, is designed to speed up identification of biomarkers and promising drug targets for four diseases: Alzheimers, rheumatoid arthritis, lupus and diabetes. Once the data are shared, the companies will be free to pursue proprietary research towards their own therapies. See go.nature.com/rn12cl for more.
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Illegal ivory crushed France destroyed 3 tonnes of poached ivory on 6February. It is the first European country to take such a step since the global ban on ivory came into force in 1989. We are resolved to continue the fight against trafficking and to remove any temptation to recover the seized ivory for black-market sales, said French environment minister Philippe Martin.
UK animal research The British government says that it is still committed to cutting the number of animals used in research, despite failing to meet a 2010 pledge to do so. The number of animal experiments in the United Kingdom topped 4million in 2012, up from more than 2.5million in 2000. On 7February, science minister David Willetts unveiled a new plan to reduce animal research, which included encouraging data sharing and providing advice on alternatives to animal testing. But he stopped short of setting a numerical limit on animal experiments. See go.nature.com/zvmeru for more.
Suicide prevention A national research agenda for suicide prevention in the United States was published on 5 February. The plan was drawn up by the National Action Alliance for Suicide Prevention, a publicprivate partnership. It sets a goal of decreasing suicides by 20% over five years. In its report, the team said that researchers should focus on the areas that will prevent the most deaths, such as identifying at-risk people through mental-health screenings in hospital emergency departments, and preventing suicidal people from accessing firearms. See page 131 for more.
Wolf plan flawed The US governments proposal to weaken protection for grey wolves (Canis lupus) is not based on good science, said an independent review panel on 7February. The US Fish and Wildlife Service (FWS) says that wolves in the lower 48states no longer face extinction (see Nature 501, 143144; 2013). But the scientists, appointed by the FWS to review its policy, found that the agency failed to use the best available science to reach its conclusions. The FWS is now reviewing its proposal and will reopen it for public comment for 45days. The government is expected to make a final decision this year.
Growing fish farms Some 62% of all the seafood eaten globally will be farm-raised by 2030, the World Bank predicts in a report released on 5February. Fish farming contributed 40% of total supply in 2010, and is projected to expand to meet growing demand from regions including Asia, the bank says. Depleted wild fish stocks will also contribute to the growth in farmed fish, the report notes.
Climate hubs US agriculture secretary Tom Vilsack announced the creation of seven regional climate hubs on 5February, to help farmers to reduce carbon emissions and cope with climate change. The hubs will provide climate data and assessments, and will support agricultural research. They are part of a move by President Barack Obamas administration to advance climate science at regional and local levels.
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Seven days: 713 February 2014
artery review for anatomy and physiology 2 elnmeer – Video
artery review for anatomy and physiology 2 elnmeer
vessels review for test.
By: ketrava
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artery review for anatomy and physiology 2 elnmeer - Video
Peroxisome proliferator activated receptor–Rho-kinase …
Peroxisome proliferator-activated receptor- (PPAR) and Rho-kinase (ROCK) regulate smooth muscle cell (SMC) proliferation and contribute to vascular remodeling in adult pulmonary hypertension. Whether these pathways interact to contribute to the development of vascular remodeling in persistent pulmonary hypertension of the newborn (PPHN) remains unknown. We hypothesized that ROCK-PPAR interactions increase SMC proliferation resulting in vascular remodeling in experimental PPHN. Pulmonary artery SMCs (PASMCs) were harvested from fetal sheep after partial ligation of the ductus arteriosus in utero (PPHN) and controls. Cell counts were performed daily for 5 days with or without PPAR agonists and ROCK inhibition. PPAR and ROCK protein expression/activity were measured by Western blot in normal and PPHN PASMCs. We assessed PPAR-ROCK interactions by studying the effect of ROCK activation on PPAR activity and PPAR inhibition (siRNA) on ROCK activity and PASMC proliferation. At baseline, PPHN PASMC cell number was increased by 38% above controls on day 5. ROCK protein expression/activity were increased by 25 and 34% and PPAR protein/activity decreased by 40 and 50% in PPHN PASMC. ROCK inhibition and PPAR activation restored PPHN PASMC growth to normal values. ROCK inhibition increased PPAR activity by 50% in PPHN PASMC, restoring PPAR activity to normal. In normal PASMCs, ROCK activation decreased PPAR activity and PPAR inhibition increased ROCK activity and cell proliferation, resulting in a PPHN hyperproliferative PASMC phenotype. PPAR-ROCK interactions regulate SMC proliferation and contribute to increased PPHN PASMC proliferation and vascular remodeling in PPHN. Restoring normal PPAR-ROCK signaling may prevent vascular remodeling and improve outcomes in PPHN.
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Peroxisome proliferator activated receptor--Rho-kinase ...
Revision to rules for color in dinosaurs suggests connection between color and physiology
2 hours ago The "rules" allowing color reconstruction from the shape of melanin-containing organelles originate with feathered dinosaurs, and are associated with an increase in melanosome diversity. However, fuzzy dinosaurs like T. rex and Sinosauropteryx show a pattern found in other amniotes like lizards and crocodilians in which a limited diversity of shapes doesn't allow color reconstruction. An explosion in the distribution of the shapes of melanin-containing organelles preserved in living taxa and the fossil record may point to a key physiological shift within feathered dinosaurs. Credit: Li et al. (authors).
New research that revises the rules allowing scientists to decipher color in dinosaurs may also provide a tool for understanding the evolutionary emergence of flight and changes in dinosaur physiology prior to its origin.
In a survey comparing the hair, skin, fuzz and feathers of living terrestrial vertebrates and fossil specimens, a research team from The University of Texas at Austin, the University of Akron, the China University of Geosciences and four other Chinese institutions found evidence for evolutionary shifts in the rules that govern the relationship between color and the shape of pigment-containing organelles known as melanosomes, as reported in the Feb. 13 edition of Nature.
At the same time, the team unexpectedly discovered that ancient maniraptoran dinosaurs, paravians, and living mammals and birds uniquely shared the evolutionary development of diverse melanosome shapes and sizes. (Diversity in the shape and size of melanosomes allows scientists to decipher color.) The evolution of diverse melanosomes in these organisms raises the possibility that melanosome shape and size could yield insights into dinosaur physiology.
Melanosomes have been at the center of recent research that has led scientists to suggest the colors of ancient fossil specimens covered in fuzz or feathers.
Melanosomes contain melanin, the most common light-absorbing pigment found in animals. Examining the shape of melanosomes from fossil specimens, scientists have recently suggested the color of several ancient species, including the fuzzy first-discovered feathered dinosaur Sinosauropteryx, and feathered species like Microraptor and Anchiornis.
According to the new research, color-decoding works well for some species, but the color of others may be trickier than thought to reconstruct.
Comparing melanosomes of 181 extant specimens, 13 fossil specimens and all previously published data on melanosome diversity, the researchers found that living turtles, lizards and crocodiles, which are ectothermic (commonly known as cold-blooded), show much less diversity in the shape of melanosomes than birds and mammals, which are endothermic (warm-blooded, with higher metabolic rates).
The limited diversity in melanosome shape among living ectotherms shows little correlation to color. The same holds true for fossil archosaur specimens with fuzzy coverings scientists have described as "protofeathers" or "pycnofibers." In these specimens, melanosome shape is restricted to spherical forms like those in modern reptiles, throwing doubt on the ability to decipher the color of these specimens from fossil melanosomes.
In contrast, in the dinosaur lineage leading to birds, the researchers found an explosion in the diversity of melanosome shape and size that appears to correlate to an explosion of color within these groups. The shift in diversity took place abruptly, near the origin of pinnate feathers in maniraptoran dinosaurs.
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Revision to rules for color in dinosaurs suggests connection between color and physiology
Tri-C develops 3-D simulation to help teach biology students complex physiology of stress
CLEVELAND, Ohio - Students in Cuyahoga Community Colleges hugely popular anatomy and physiology classes will soon have access to a sleek new 3-D teaching tool developed by their own professors and e-learning experts. The program, called the Tri-C 3-D Stress Simulator, is designed to help students learn complex physiology through 3-D simulation.
The teaching tool is the result of a yearlong collaboration between three biology professors and the schools Office of eLearning and Innovation, which funded the project with $80,000 from its annual budget earmarked for interactive learning.
It takes about 12 to 15 hours to complete, and allows students to navigate through simulations of the stress response at the whole body and cellular level at their own pace, while they answer questions on the subject material and watch animations.
Were basically flying through the material trying to get everything in thats required by the curriculum, said Christopher Caprette, assistant professor of biology at Tri-C and one of the developers of the simulation. What weve learned is that every student has their own learning style, every faculty member has their own teaching style, and these dont always match. So any additional way of presenting the material is a good thing.
The anatomy and physiology (A & P) classes were targeted because they are the highest enrollment classes at Tri-C, with about 1,500 students per term signed up for two levels of courses. The classes are pre-requisites for many of the health and medicine career tracks the college offers, including nursing, physician assistant, occupational therapy and others.
A poll of students in December of 2012 also revealed that A & P was one area where students felt they could use the most extra help, said Cynthia Conaway-Mavroidis, assistant professor of biology at Tri-C and co-developer of the simulation. Assistant professor Anne Marie Yunker also helped develop the program.
Three of the schools A & P classes are currently using the simulation during a pilot of the software, Conaway-Mavroidis said. One course used it in the fall in both campus-based and online courses.
The team chose to model the bodys stress response because it involves several body systems interacting simultaneously, Caprette said.
They can then see how things sort of integrate into a whole system, he said. Thats something thats pretty hard to get across.
I think the one overwhelming comment was that [the simulation] really helped them understand the topic better, Conaway-Mavroidis said. Several of my students have said it would be helpful to use a little of this after every topic covered in class.
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Tri-C develops 3-D simulation to help teach biology students complex physiology of stress
University Of Maryland School Of Medicine Establishes New Brain Science Research Consortium Unit To Study The …
Bankole A. Johnson, DSc., M.D., MPhil, will lead the University of Maryland School of Medicine's new Brain Science Research Consortium Unit. (PRNewsFoto/University of Maryland School of Medicine)
BALTIMORE, Feb. 12, 2014 /PRNewswire-USNewswire/ -- University of Maryland School of Medicine Dean E. Albert Reece, MD, Ph.D., MBA, announced today the establishment of a new brain science research unit that will bring together faculty from multiple disciplines to probe the inner workings of the brain and to develop therapies for a wide range of neurological disorders.
(Photo: http://photos.prnewswire.com/prnh/20140212/DC63473)
The new Brain Science Research Consortium Unit (RCU) will conduct large-scale, multidisciplinary studies on brain function (and dysfunction). Physician-scientists, laboratory scientists and other translational and clinical investigators across the university will collaborate in this important undertaking.
"Tackling an area of research with as much intricacies as brain science requires significant collaboration from investigators across many disciplines because no single person will have all the answers," said Dean E. Albert Reece, M.D., Ph.D., M.B.A., vice president for medical affairs at the University of Maryland and the John Z. and Akiko K. Bowers distinguished professor and dean of the School of Medicine. "The School of Medicine's Brain Science RCU breaks through the traditional silos, where basic research is separated from clinical work, and brings together a team of experts from multiple fields to understand the body's most important organ. We anticipate unprecedented discoveries that will measurably and dramatically impact the area of brain research."
The Brain Science RCU will set out to answer challenges presented by the NIH BRAIN (Brain Research through Advancing Innovative Neurotechnologies, also referred to as the Brain Activity Map Project), a national research program announced by President Obama last year. The program was established to revolutionize how we understand the human brain and mind, and to find new ways to identify and treat disorders such as Parkinson's disease, schizophrenia, Alzheimer's disease, autism, stroke, and brain injury.
University of Maryland School of Medicine researchers will be well poised to align their expertise with the BRAIN Initiative's goals, forming interdisciplinary groups to form large research projects on:
The School of Medicine's Brain Science RCU will be led by Bankole A. Johnson, DSc, MD, MB, ChB, MPhil, Professor and Chair of the Department of Psychiatry and Behavioral Science. His primary area of research expertise is the psychopharmacology of medications for treating addictions, and he is the author of more than 200 research publications. He is the principal investigator on National Institutes of Health (NIH)-funded studies utilizing neuroimaging, neuropharmacology, and molecular genetics techniques. Professor Johnson is a neuroscientist and neuropsychopharmacologist whose work spans basic, translational and the clinical sciences, including the use of molecular genetics and neuroimaging to develop medicines for the treatment of addictions.
Professor Johnson will lead a steering committee of School of Medicine faculty, which will determine research areas for the Brain Science RCU to follow, and develop multidisciplinary centers of excellence to submit research grants, conduct large-scale studies and make joint discoveries in how the brain works and what causes brain disorders. The Brain Science RCU will bolster research ties with other parts of the School of Medicine and University, including the departments of neurology, neurosurgery, neurobiology, and psychiatry, the SOM Center for Shock Trauma and Anesthesiology Research (STAR), the Maryland Psychiatric Research Center (MPRC), and the University of Maryland Medical System.
"The human brain is arguably the most complex entity in the universe that we know of," said Professor Johnson. "We do not understand all that the brain is capable of, nor how everything functions. The Brain Science RCU will allow us to develop revolutionary techniques, methods and knowledge to help our understanding of brain function that only a large, interdisciplinary enterprise can do."
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University Of Maryland School Of Medicine Establishes New Brain Science Research Consortium Unit To Study The ...
Top Anti-Aging Doctor at Phoenix Integrative Medicine Now Offering PRP Facelift Procedure
Phoenix, Arizona (PRWEB) February 12, 2014
Top Anti-Aging doctor at Phoenix Integrative Medicine, Dr. Andrea O'Connor, is now offering the PRP Facelift. The treatment, also known as the Vampire Facelift, is highly effective at using the bodys own healing process to generate newer younger skin. For more information and scheduling call (480) 252-3799.
Traditional facelift procedures involve incisions, anesthesia and significant recovery time. With the latest regenerative medicine procedure known as the PRP Facelift, none of these things are necessary. Patients receive the procedure as an outpatient, and no incisions are needed.
For the treatment, blood is taken from the patient just like a blood draw at a lab. The blood is then spun in a centrifuge which creates a layer rich in platelets and growth factors. This concentrate is then used for the facelift procedure, which also attracts stem cells from the body. Some call the treatment a "stem cell facelift" because of this. Because it is the patient's own blood, there is minimal risk with the treatment.
A PRP facelift can help to reduce the presence of scars, wrinkles, and fine lines on the skin to allow for a more natural and more youthful look. The effects of a PRP facelift can last for over six months, and are typically able to be seen in the days immediately following the procedure.
In addition to the PRP facelift (aka Vampire Facelift or Stem Cell Facelift), Phoenix Integrative Medicine also offers Botox, Juvederm, Dysport, bioidentical hormone replacement and much more.
Those interested should call (480) 252-3799 for more information and scheduling.
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Top Anti-Aging Doctor at Phoenix Integrative Medicine Now Offering PRP Facelift Procedure
Comets Corner with Rob Esche
February 11, 2014 - American Hockey League (AHL) Utica Comets Every four years, the hockey community around the world, stretching from Russia to Sweden to New York, celebrates the most famous hockey event this world will ever know - the Winter Olympics. While the Vancouver Canucks have six players representing Sweden, Canada, Switzerland and the USA, including former Comets player Yannick Weber, there is someone a little closer to home who had the once in a lifetime experience of representing his country in the Olympics. And this Olympian is the one responsible for bringing professional hockey back to Utica, New York.
Robert Esche, president of the Utica Comets, was selected to the 2006 USA Men's Hockey team while playing for the Philadelphia Flyers, and traveled to Turin, Italy to compete against the rest of the world. "It was obviously something that was kind of surreal," Esche explained. "When I was growing up, my grandmother always wished that I would play in the Olympics. When I found out I was going, the first person I thought of was my grandmother and calling her to tell her the news. It was such a special conversation."
As a young hockey player, Esche set his goals high, and always pictured himself reaching the Olympics someday. "It was always a goal to play in the Olympics," he recalled. "I think that every kid who grows up playing an Olympic sport wants to make it there. For me, it was always a goal." When that dream finally came true in February of 2006, it was time for Esche to pack his bags and head to Europe, leaving the NHL for a couple of weeks. "Because the Olympics occur in the middle of the hockey season, as they get closer and closer, it becomes a little trickier to keep your head in the NHL games," Esche admitted. "Your mind constantly drifts, and you envision yourself playing in Turin. You're supposed to be a professional player, but it's human nature for playing in the Olympics to creep into your thoughts."
For anyone, especially a first-time Olympian, Esche recalls feeling overcome with emotions and pride when representing his country in front of millions of individuals worldwide. "I think that any time you represent your country, it's a different feeling [than the NHL]," he said. "You feel like you're representing millions upon millions of people as opposed to when you play for your city and you're just representing a team. There's so much camaraderie from fans and athletes and anyone who puts on the USA jersey." Esche also went on to explain that emotions run deep, especially when thinking about the history of the United States of America. When asked what makes the Olympics different from playing in other important professional hockey games throughout his career, Esche explained, "I think the fact that the whole nation's eyes are on you, whether you're from Chicago, New York, Philadelphia, Boston or LA makes the Olympics a once in a lifetime experience. Everyone's pulling for you. There are a lot of thoughts that come up, whether they're about the wars or the freedom that we live, but those emotions are unforgettable and powerful."
As the 22nd Winter Olympics are upon us, there has been much talk about the conditions athletes and press are being subjected to while in Sochi, Russia. Esche was able to offer a different perspective on the games, coming from someone who experienced them himself. "The conditions in Sochi shouldn't be an excuse for anybody because the athletes have sacrificed everything to get to where they are now," he explained. "I think the conditions are part of Russia's culture, which a lot of people don't realize and take for granted. In Italy, the conditions were very different because the culture was so different. That's part of what makes the Olympics so special...you deal with the different make-ups of people on such a global stage." When asked what his favorite memory from the Olympics was, Esche didn't hesitate with an answer. "Having my whole family over there was by far the most special thing for me. We were able to spend some time together...not a lot of time, but a meal here and there. It was really special."
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Solon Comets move up to No. 1 in cleveland.com girls basketball Top 25 poll for Feb. 11, 2014 (video)
CLEVELAND, Ohio -- The Solon Comets girls basketball team started the season ranked No. 1 in the cleveland.com poll, and on Tuesday, they made it back to the top of the poll.
Three top five teams lost last week, allowing Magnificat to move up to No. 3 in the poll.
We are excited to introduce comments to allcleveland.comhigh school sports stories this school year. Please sound off and share your top 25 in the comments section at the bottom of this post.
Which girls basketball team do you think is the best in Northeast Ohio? Let us know in the comments.
(Records through Monday. Last week's ranking in parentheses.)
1. Solon, 18-3 (2)
Trending: Rising.
Last week: Defeated then- No. 1 Wadsworth and Shaker Heights.
This week: Wednesday vs. Twinsburg.
The Comets have felt disrespected in the state AP poll, and used that as motivation to defeat previously undefeated Wadsworth.
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Laura Deanovic: Living with Psoriasis – Video
Laura Deanovic: Living with Psoriasis
Live Bold, Live Now - HealthCentral.com In her mid-40s and now a professional boxer, Laura Deanovic is winning the fight against psoriasis - the disease that...
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Online Travel Security from E-travelsafety.com
Hereford, Herefordshire (PRWEB UK) 12 February 2014
As the world becomes more accessible and travelled, so does the need to provide a cost effective, hassle free travel safety solution. E-travelsafety.com believes that by incorporating a few simple actions when travelling, it will greatly increase your travel security.
E-travelsafety.com have designed and developed, a low cost, hassle free travel safety online training package. The interactive cloud based package, provides all the travel safety and travel security advice you need, to reduce the risk when travelling. This includes world-wide destination guides, a pre-travel risk assessment, how to react in emergency situations, downloadable guides and travel security hints and tips to help you stay safe when travelling.
The travel safety e-learning course is only 30 per year, that provides the user with all the travel security advice and training they need throughout this period. It is designed to be used over and over again and can be used for travel to any country in the world.
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e-travelsafety.com provides travel safety advice, through an interactive e-learning package. The team has many years experience in travel safety and travel security, from teaching individuals, to multinational corporations, all around the globe. This has involved the delivery of pre-travel training, assisting deployment, and also managing travel, from remote locations, to tourist destinations. During this time e-travelsafety.com has gained an understand of the market and believed that a cost effective Travel Safety solution could be produced, that was not only hassle free but also easy to use by anyone.
Safe travels!
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'Super computer' says Tim Sherwood is right: Spurs CAN lose four games and reach the Champions League
Tottenham boss Tim Sherwood has claimed his team could lose four orfive of their remaining 13 Premier League matches and still finish in the top four.
"I would say we can possibly afford to lose four or five games maybe of what we've got left," said Sherwood, while admitting his maths isn't the best.
But can Spurs really lose that many games and still qualify for the Champions League?
We asked the sports data analysts at Bloomberg Sports to crunch the numbers, using a complex algorithm, and they have calculated Tottenham's most likely results between now and the end of the season, as well as the number of points Spurs are most likely to collect and how many they will likely need to finish fourth.
First, here are the results predicted by the Bloomberg Sports boffins with percentages allocated to the likelihood of either a win, loss or draw
Next is a graphic illustrating the most likely points totals Spurs will achieve, with the Lilywhites calculated to have the highest chance (7.5 per cent) of finishing with 67 points.
Finally, after running their simulator over 100,000 times, Bloomberg Sports have calculated that a total of 74.5 points would secure fourth place.
It is not possible to score 0.5 of a point, of course, so assuming that 74 points would be enough to take fourth, that would leave Tottenham on 47 points at time of writing able to lose four of their remaining 13 games and still able to reach the desired total, if they won the other nine to rack up another 27 points.
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