AIP Aerospace Acquires Brown Aerospace

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Santa Ana, CA - AIP Aerospace announced today the acquisition of Brown Aerospace, a leading provider of automated drilling and fastening systems for the aerospace industry. Brown will operate as a business unit within the AIP Aerospace Tooling Group.

Brown Aerospace was founded in 2001 and is located in Kimball, Michigan. With a singular focus on the aerospace industry, Brown is well-respected for the automated fastening solutions it provides to customers, such as Boeing, Spirit and Mitsubishi Heavy Industries.

Mark Brown will continue as the Director of Operations and brings with him 20 years experience with complex aerospace drilling and fastening solutions, including a high level of expertise in engineering, operations and sales expertise.

Were excited to welcome Brown Aerospace to the AIP Aerospace family, stated Brian Williams CEO of AIP Aerospace. Not only will Brown be a perfect fit with our existing customer base, it will allow us to offer full factory integrated systems that will drive incremental growth in our tooling business.

For more information about the AIP Aerospace Tooling Group, visit http://www.aipaerospace.com/tooling.

About AIP Aerospace

AIP Aerospace is one of the largest independent aerospace tooling group providers and suppliers of high temperature composite parts, critical components, aircraft structures, transparencies, and coating technologies. Our strategically aligned Tooling Group and Aerostructures and composites companies harness the unrivaled expertise of our dedicated industry professionals and state-of-the-art facilities across the US. Visit http://www.aipaerospace.com for more information.

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AIP Aerospace Acquires Brown Aerospace

Vector Aerospace Helicopter Services North America Displays Modified Integrated Cockpit at Heli-Expo 2014

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Richmond, BC Vector Aerospace (www.vectoraerospace.com), a global independent provider of aviation maintenance, repair and overhaul (MRO) services, is pleased to announce that Vector Aerospace Helicopter Services North America (HS-NA), a subsidiary of Vector Aerospace and one of the worlds leading providers of helicopter maintenance, repair and overhaul services will have a custom-modified integrated cockpit on display at Heli-Expo, Booth #5906.

Certified by Vector Aerospace, the integrated cockpit display reduces pilot workload and provides improved features including maps, weather radar, maintenance page, and warning annunciations, states Chris McDowell, Vice President Sales and Marketing. This modification is a great example of how Vector continues to generate customized solutions for its customers.

The cockpit consists of two Sagem 10 MFD (EI indication) and two Sagem 10 PFDs for right or left hand seat operations, and is just one example of Vectors full UH-1H upgrade capabilities.

HS-NAs comprehensive helicopter service portfolio includes: dynamic components, full-service avionics capability; up to and including glass cockpit engineering, development and integration, complete aircraft rewires, as well as airframes and major inspections support for a variety of Airbus, Sikorsky, Boeing and Bell helicopter models; Rolls-Royce M250; Rolls-Royce T56/501D; Pratt & Whitney Canada PT6T series engines; Turbomeca Arriel 1 and Arriel 2 and General Electric T58 / CT58 and CT-7A / T700 engines (all engine lines include complete test capability).

About Vector Aerospace

Vector Aerospace is a global provider of aviation maintenance, repair and overhaul (MRO) services. Through facilities in Canada, the United States, the United Kingdom, France, Australia, South Africa and Kenya, Vector Aerospace provides services to commercial and military customers for gas turbine engines, components and helicopter airframes. Vectors customer-focused team includes over 2,700 motivated employees.

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Vector Aerospace Helicopter Services North America Displays Modified Integrated Cockpit at Heli-Expo 2014

Deep TCR sequencing reveals extensive renewal of the T cell repertoire following autologous stem cell transplant in MS

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A new study describes the complexity of the new T cell repertoire following immune-depleting therapy to treat multiple sclerosis, improving our understanding of immune tolerance and clinical outcomes.

In the Immune Tolerance Network's (ITN) HALT-MS study, 24 patients with relapsing, remitting multiple sclerosis received high-dose immunosuppression followed by a transplant of their own stem cells, called an autologous stem cell transplant, to potentially reprogram the immune system so that it stops attacking the brain and spinal cord. Data published in the Journal of Clinical Investigation quantified and characterized T cell populations following this aggressive regimen to understand how the reconstituting immune system is related to patient outcomes.

ITN investigators used a high-throughput, deep-sequencing technology (Adaptive Biotechnologies, ImmunoSEQTM Platform) to analyze the T cell receptor (TCR) sequences in CD4+ and CD8+ cells to compare the repertoire at baseline pre-transplant, two months post-transplant and 12 months post-transplant.

Using this approach, alongside conventional flow cytometry, the investigators found that CD4+ and CD8+ lymphocytes exhibit different reconstitution patterns following transplantation. The scientists observed that the dominant CD8+ T cell clones present at baseline were expanded at 12 months post-transplant, suggesting these clones were not effectively eradicated during treatment. In contrast, the dominant CD4+ T cell clones present at baseline were undetectable at 12 months, and the reconstituted CD4+ T cell repertoire was predominantly composed of new clones.

The results also suggest the possibility that differences in repertoire diversity early in the reconstitution process might be associated with clinical outcomes. Nineteen patients who responded to treatment had a more diverse repertoire two months following transplant compared to four patients who did not respond. Despite the low number of non-responders, these comparisons approached statistical significance and point to the possibility that complexity in the T cell compartment may be important for establishing immune tolerance.

This is one of the first studies to quantitatively compare the baseline T cell repertoire with the reconstituted repertoire following autologous stem cell transplant, and provides a previously unseen in-depth analysis of how the immune system reconstitutes itself following immune-depleting therapy.

About The Immune Tolerance Network

The Immune Tolerance Network (ITN) is a research consortium sponsored by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health. The ITN develops and conducts clinical and mechanistic studies of immune tolerance therapies designed to prevent disease-causing immune responses, without compromising the natural protective properties of the immune system. Visit http://www.immunetolerance.org for more information.

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The above story is based on materials provided by Immune Tolerance Network. Note: Materials may be edited for content and length.

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Deep TCR sequencing reveals extensive renewal of the T cell repertoire following autologous stem cell transplant in MS

Center for Electron Paramagnetic Resonance (EPR) Imaging in Vivo Physiology – University of Chicago – Video

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Center for Electron Paramagnetic Resonance (EPR) Imaging in Vivo Physiology - University of Chicago
The Center for Electron Paramagnetic Resonance (EPR) Imaging in Vivo Physiology is a consortium of institutions working to invent in Vivo imagers. The Center...

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Center for Electron Paramagnetic Resonance (EPR) Imaging in Vivo Physiology - University of Chicago - Video

Blazing trails in brain science

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Dr. Tom Insel, the longest-tenured director of the National Institute of Mental Health in almost half a century in Rockville | credits: New York Times Service

The police arrived at the house just after breakfast, dressed in full riot gear, and set up a perimeter at the front and back. Not long after, animal rights marchers began filling the street: scores of people, young and old, yelling accusations of murder and abuse, invoking Hitler, as neighbors stepped out onto their porches and stared.

It was 1997, in Decatur, Ga. The demonstrators had clashed with the police that week, at the Yerkes National Primate Research Centre at nearby Emory University, but this time, they were paying a personal call on the house of the centres director, inside with his wife and two teenage children.

I think it affected the three of them more than it did me, honestly, said Dr. Thomas R. Insel, shaking his head at the memory. But the university insisted on moving all of us to a safe place for a few days, to an undisclosed location.

Ill say this. I learned that if youre going to take a stand, youre going to make some people really angry so youd better believe in what youre doing, and believe it completely.

For the past 11 years, Insel, a 62-year-old brain scientist, has run an equally contentious but far more influential outfit: the National Institute of Mental Health, the worlds leading backer of behavioral health research.

Insel has not merely survived; he is the longest-serving director since Dr. Robert H. Felix, the agencys founder, retired almost a half-century ago. His tenure stretches over three presidencies and, more important, coincides with a top-down overhaul in the substance and direction of behavioral science.

The extent of this remodeling is not widely understood outside scientific circles nor universally appreciated within them. But in recent months, its author has begun to reveal his instincts publicly, in blog posts and speeches.

Last summer, he questioned whether people with schizophrenia should remain indefinitely on antipsychotic medications a shot at accepted medical wisdom.

A few months earlier, he had called out psychiatrys diagnostic encyclopedia, the DSM-5, as not scientifically valid, weeks before a new edition was released. Psychiatrists were not happy, and they told him so. Days later, he issued a statement saying that the manual was the best currently available, if imperfect.

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Blazing trails in brain science

Comets Corner: 50/50

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February 18, 2014 - American Hockey League (AHL) Utica Comets Since October of 2013, the Comets have made an overwhelmingly positive impact on the Mohawk Valley. Both on and off the ice, the Comets continue to succeed and create an exciting environment for the community. One of the most successful components of a Comets game day, however, might not be what most people might have expected coming into the season.

The Utica Comets 50/50 has been a key facet of every game day here at the Utica Memorial Auditorium. Managed by Janice Martino, a dedicated youth hockey parent, the total pot has not dropped below $2,000 yet this year, with the record breaking total of $15,436 coming on January 31st, 2014. This total also set the record in the AHL for this season. January 31st was also Pink the Rink, a night dedicated to honoring those affected by breast cancer. It just so happened that, by chance, of course, the 50/50 winner was a breast cancer survivor. "It's nights like those," Janice Martino explained, "when I know that I am lucky to be a part of something so special going on in my hometown."

For someone with no initial experience managing a 50/50 system, Martino immediately knew that she wanted to be a part of the inaugural season. "When I was asked to shoulder the responsibility of administrating the 50/50, I didn't hesitate. I have three boys who play youth hockey and have always been very involved in Mohawk Valley youth hockey since they began playing," she said. "As a family, we spend huge amounts of time in that building and my boys feel that building is their home. When the announcement came that the Comets were coming, we weren't immediately sure what that would mean to our organization. What has happened since has been extraordinary. Mr. Esche has been so supportive of youth hokey in our area and in our building in particular. His vision for our area and the Utica Jr. Comets is larger than life." Martino explained that the proceeds go directly to the Save of the Day Foundation, and in turn, they donate a portion to the Utica Jr. Comets youth hockey program.

Most people may not realize how much time and planning goes into running a successful 50/50 system. "Game day planning begins a month earlier with an e-mail sent out to all Jr. Comet parents looking for volunteers for that month's games," Martino explained. "For each game, I require a minimum of seven people to volunteer to make this thing work. There's really no direct benefit for them, either. They are too busy to actually watch the game and are generally in building for four hours." Despite being volunteers, Martino raves about the staff she works with. "I have been blessed with the absolute best volunteer staff imaginable," she exclaimed. "We have a blast on game day. When you get a group of people together who are willing to give of themselves for a worthy cause, you can bet they are a group you enjoy being around."

On an actual Comets game day, Martino begins her day around 4:30, making sure everything is in order for the evening. The printers and handhelds have to be checked to make sure they're working. Most people don't realize that each ticket has to be physically printed, per NY State requirements. These tickets also have to be saved for three years. "Some of the game day tasks are simple, such as getting the t-shirts for the sellers, stocking paper, getting starting cash for each seller etc," she described. "Some tasks are more detailed because of all the technology involved in our system."

After the sellers work their magic during the game, Martino awaits the winning number, which is usually drawn with about a third of the third period remaining. She must wait until the printer prints all of the tickets, which can be a wait as the printers can easily get backed up. "Contrary to what some people believe, with the exception of opening night, every prize has been claimed," she added. "I could probably tell you a story about almost any winner that has claimed a prize to date. There's always something special about the win. I've had birthday boys, pregnant moms, and a guy who had to fish the winning ticket out from behind the glass."

Janice Martino's night doesn't end when the building clears out. There's a lot of cleaning up to do, logging out of volunteers and counting money. Despite Martino being one of the last to leave The AUD, she wouldn't trade the experience for anything.

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Comets Corner: 50/50

Comets skate to pair of wins

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The Utica Comets picked up a pair of one-goal American Hockey League victories over the weekend to improve to 20-23-3-4 overall on the season.

They defeated the Toronto Marlies, 2-1, at the Ricoh Coliseum Sunday afternoon, a day after downing the Rochester Americans by the same score on Saturday in front of a packed house at the Utica Memorial Auditorium.

With the wins the Comets have collected a point in 11 of its past 14 games.

On Sunday, Utica rode a penalty killing unit that killed off 8 of 9 Marlies power play opportunities, and goalie Joe Cannatas 25 saves for the victory.

The Comets recorded goals from Jeremy Welsh and Pascal Pelletier. Colin Stuart, Kent Huskins, and Alex Biega picked up the Comets assists.

Utica picked up its first win of the season over Toronto after losing twice to before, both by the score of 5-2.

Drew MacIntyre finished with 26 saves on 28 Comets shots on goal, and Kozun picked up his 14th goal of the year.

In front of a sold out crowd at the Aud on Saturday, the Comets avenged a 7-3 loss the previous night in Rochester. With the win, Utica has won four of five games on their home ice.

Nicklas Jensen and Brandon DeFazio had the goals for the winners, while netminder Joacim Eriksson made 31 saves on 32 shots to earn his 14th victory of the season. Alex Biega, Yann Sauve and Kellan Lain each recorded assists for Utica.

Matt Hackett finished with 25 saves on 27 shots for Rochester, as he fell for just the second time this season against the Comets.

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Comets skate to pair of wins

Comets clout CAL in 1st round

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GRUNDY CENTER - Just three days ago, Charles City knocked off Class 3A No. 1 Clear Lake.

It was the first loss of the season for Clear Lake and just the seventh win of the year for Charles City.

But it was a game that was referenced by BCLUW coach Austin Schlatter to his Comets before the squad opened Class 1A District 4 play Monday.

T-R PHOTO BY TROY HYDE BCLUW senior Lane Caster (20) shoots over CALs Hunter Schleisman during the Comets 65-32 Class 1A District 4 win on Monday night in Grundy Center. Caster scored nine points in the victory. T-R PHOTO BY TROY HYDE BCLUW junior Ty Runge gets fouled from behind against a defender from CAL during the Comets 65-32 Class 1A District 4 win in Grundy Center. Runge scored 11 points on the night.

It was to show the Comets that upsets can happen and do happen. And it helped BCLUW not overlook 2-19 CAL, while also showing the Comets that anything can happen in the postseason moving forward.

Conner Ubben sidetracked early foul trouble and finished with 16 points, while Cole Silver and Ty Runge both scored 11 and the Comets avoided the first-round upset with an easy 65-32 victory over CAL.

"It's pretty nice to win," said Ubben. "You think about G-R in the back of your head before the game but once the game starts you have to kick it out of your mind. You have to take every team seriously."

BCLUW 65, CAL 32

At Grundy Center

CAL (2-20) - Mario Yanez 1 0-0 3, Austin Guerrero 3 0-2 8, Juan Carlos Calles 2 3-4 7, Caleb Striegel 2 0-0 4, Hunter Schleisman 3 1-2 7, Juan Gomez 1 1-2 3. TOTALS 12 5-10 32.

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Comets clout CAL in 1st round

Thomas Armstrong continue Workington Comets speedway sponsorship

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Last updated at 12:37, Tuesday, 18 February 2014

Workington Comets have announced that their main team sponsor, Thomas Armstrong, will continue their association with the team this season.

Laura Morgan

It is the eighth successive season the west Cumbrian construction firm will sponsor the team and they will be joined by both key partners from last season, J Edgar & Son, who were official team sponsors in 2003, and Ast signs.

All three businesses will once again have their names incorporated within the Comets race jacket for 2014.

Comets owner Laura Morgan said: The backing of such high-profile and well-respected Cumbrian- based businesses is invaluable to us.

We are very appreciative of their continued support of the Comets as we embark on what we hope will be a very successful season for all parties.

As a new promotional team last season we were very pleased with the support we got from all of our sponsors but especially Thomas Armstrong, J Edgar & Son and Ast signs, whose assistance throughout the season was instrumental in what was a successful first season for us as promoters.

We would like to think that we played a part in promoting their businesses locally and, through our television appearance, to a wider audience; and hopefully we can continue to do that in 2014.

First published at 12:23, Tuesday, 18 February 2014 Published by http://www.newsandstar.co.uk

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Thomas Armstrong continue Workington Comets speedway sponsorship