Red-Light Camera Fines In Effect At New Philly Intersection

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Nutter Gives Emotional Response During Budget Announcement Nutter Gives Emotional Response During Budget Announcement

Updated: Thursday, March 6 2014 7:50 PM EST2014-03-07 00:50:45 GMT

Mayor Nutter's New Philadelphia budget plan may make some folks happy.The proposal calls for increased investments in city parks and recreation centers, libraries and L&I Inspectors.

Mayor Nutter's New Philadelphia budget plan may make some folks happy.The proposal calls for increased investments in city parks and recreation centers, libraries and L&I Inspectors.

Updated: Thursday, March 6 2014 4:18 PM EST2014-03-06 21:18:04 GMT

A retired police officer is under arrest and facing child sex assault charges for an alleged relationship with a girl when she was a teenager, FOX 29 News has learned.

A retired police officer is under arrest and facing child sex assault charges for an alleged relationship with a girl when she was a teenager, FOX 29 News has learned.

Updated: Thursday, March 6 2014 4:00 PM EST2014-03-06 21:00:23 GMT

According to police, two 8-year-olds and one 9-year-old were caught smoking pot in their school's bathroom. Now, they're wondering how the kids got their hands on the substance."Shocked," said Linda Rodriguez

According to police, two 8-year-olds and one 9-year-old were caught smoking pot in their school's bathroom. Now, they're wondering how the kids got their hands on the substance.

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Red-Light Camera Fines In Effect At New Philly Intersection

45 Disappearing Rocks Photoshop Mars Fake Nasa Fraud GOOD EYES snafu Rover site Mar 4, 2014 – Video

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45 Disappearing Rocks Photoshop Mars Fake Nasa Fraud GOOD EYES snafu Rover site Mar 4, 2014
UFOsightings hotspots, had this up and he/she is correct. This is NASA photoshop, even tho Rock #2 still exists in an illogical way. Part 45 of series on mar...

By: TheHumanDuplicators

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45 Disappearing Rocks Photoshop Mars Fake Nasa Fraud GOOD EYES snafu Rover site Mar 4, 2014 - Video

NASA Armstrong Flight Research Center: A Vision for the World of Flight – Video

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NASA Armstrong Flight Research Center: A Vision for the World of Flight
This fast-paced video highlights some of the flight research and other activities that occurred at NASA #39;s Dryden Flight Research Center in 2013, and looks ah...

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NASA Armstrong Flight Research Center: A Vision for the World of Flight - Video

NASA mission to Europa takes small step toward reality (+video)

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NASA's 2015 budget includes a small down payment on a potential mission to Europa, a moon of Jupiter and one of the solar system's potentially most habitable spots.

Europa or bust?

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In its fiscal 2015 budget, NASA has included a small deposit on a possible mission to one of the solar system's potentially most habitable spots: Jupiter's ice-sheathed moon Europa.

The agency is asking Congress for $15 million to officially begin identifying affordable concepts for a Europa mission, noted Elizabeth Robinson, NASA's chief financial officer, at a briefing on Tuesday.

At the moment, the agency has no official cost estimate for such a mission and a launch date no more specific than sometime in the mid-2020s. But a 2012 study commissioned by NASA highlighted three approaches that carried price tags ranging from $1.8 billion to $3 billion. Of those, the study team identified a $2.1 billion mission as the one that would return the most science for the best price. It consisted of a spacecraft performing multiple flybys of Europa.

While $15 million may seem like chump change against a potential price tag of $2 billion, give or take, putting the figure in the budget "is significant, it means we're getting serious," says James Green, who heads NASA's planetary science division.

Congress has already delivered $80 million to NASA to begin spadework on a mission to Europa in mind. Now, by putting the mission in the budget, the Office of Management and Budget (OMB) is giving the program a new level of concreteness, since it must include spending estimates for an additional four years beyond fiscal 2015.

"The fact that OMB put it in as line item by name says that administration finally got the message that Congress was going to insist on this and they might as well go ahead and put it in the budget," says Scott Hubbard, former head of NASA's Mars exploration program and now a consulting professor of aeronautics and astronautics at Stanford University in Palo Alto, Calif.

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NASA mission to Europa takes small step toward reality (+video)

Is NASA really going to send a probe to Europa? [w/updates]

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NASA said Tuesday that it wants to plan a robotic mission to Jupiters watery moon Europa, where astronomers speculate there might be life. (1996 photo of Europa/AP Photo/NASA)

Whats NASA really up to? Sometimes its hard to know for sure. For a number of years NASA has developed various programs and missions that did not survive the erosional forces of constricting budgets and strategic changes. The agency has a dilemma: It takes at least a decade to do anything significant in space, but our political cycle is faster than that. Thus there are these phantom programs that exist on paper, that look like real plans, but which may never become physical, tangible realities. As a reporter covering NASA programs, you want to add a stipulation somewhere in your story that says, in effect, This may not actually happen.

Even programs where the metal has already been cut can wind up in the trash heap. The Constellation Program of Bush 43 was a major effort to return astronauts to the moon, but it never felt 100 percent real, because the plan lacked any sense of political urgency or public buy-in. It felt vulnerable to shifting winds. And such a wind came along the zephyr known as Barack Obama. Obama killed Constellation. That meant the demise of the Ares 1 rocket after it had already burned through billions of dollars. And what were they going to do with that $500 million, brand-new mobile launcher at the Cape that was designed for the Ares 1? (Answer: They can probably re-purpose it for another rocket, but space hardware is so customized that its not like adjusting the height knob on a workout machine at the gym.)

Surviving from Constellation is the Orion capsule, but where will you go with it, if not back to the moon? NASA last year proposed the Asteroid Redirect Mission, which would involve astronauts in Orion visiting a captured asteroid in lunar orbit. In the new FY2015 budget request, the Obama administration wants to boost funding for the ARM, to $133 million in 2015, but you can expect political rancor on that front. The ARM is hardly a slam dunk, in part because they havent found a target rock. Republicans dont like it because it has Obamas imprimatur, and they took the rare step last year of trying to prevent NASA from spending any money on it. The ARM has no international partners. It is not essential to the hopes and dreams and bottom lines of the huge aerospace corporations (although a captured rock would give Orion and the SLS rocket a destination in the relatively near term other than points in space or interesting orbits around the moon). So the ARM lives, but its precisely the kind of program that a subsequent Congress or Republican administration would take delight in killing.

Which finally brings up the issue of a Europa mission. Seth Borenstein of the Associated Press wrote about the Europa proposal Tuesday. (Could be fish under the ice there!) Theres $15 million in the Obama budget request for a Europa mission (heres my news article that touches on the NASA budget its mostly about the United States and Russia being roommates in space). But a Europa mission would be a Flagship class mission, meaning $1 billion-plus in cost. NASA Administrator CharlesBolden said a few months ago that the space agency couldnt afford new Flagships in the near future (other than ones already underway). Other officials confirmed that: Theres no money in the tight NASA budget for Flagships right now. Any plausible mission to Europa is definitely Flagship-class, as I reported in December in the final installment of the Destination Unknown series.

Initial estimates for a Europa orbiter put the cost at $4.7 billion. Thats expensive even by flagship-mission standards. Getting a spacecraft into orbit around Europa is tricky, because its close to Jupiter and at the bottom of the planets deep gravity well. Jupiter also emits intense radiation, and the spacecrafts instruments would need to be covered in costly lead shielding.

So engineers went to a Plan B. Rather than orbiting Europa, the spacecraft would go into an orbit around Jupiter, spending most of its time outside the planets radiation field, and then swoop in repeatedly, with 34 flybys of Europa and nine of the moon Ganymede.

At this point the Europa Clipper is just a concept under study, and it is not clear when or if it will graduate and become a real mission.

So, does NASA intend to do a Flagship-class Europa mission? What do we make of the $15 million in the budget request? Reporters on the NASA budget teleconference Tuesday pressed Bolden to clarify the issue. He didnt. Finally, NASA chief financial officer Elizabeth Robinson said the Europa mission is in the early pre-formulation stage and said of the future scale of the mission, Were frankly just not sure at this point.

One likely outcome is that Congress will see the $15 million request from the administration and raise it substantially. That was suggested to me by Rep. Adam Schiff , the Democrat who represents Pasadena (home base of NASA Jet Propulsion Laboratory) and who is a big booster of the NASA planetary program.

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Is NASA really going to send a probe to Europa? [w/updates]

Diasome Pharmaceuticals, Inc. Announces Notice of Allowance for Novel Nanotechnology Weight Loss Patent from the US PTO

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Cleveland, Ohio (PRWEB) March 06, 2014

Diasome Pharmaceuticals, Inc. (http://www.diasome.com) has received notice from its licensor, SDG, Inc., that SDG has received a notice of allowance for its novel weight loss nanotechnology patent application. This patent, entitled Orally Bioavailable Lipid Constructs, covers composition of matter claims related to the use of the Companys proprietary oral Hepatocyte Directed Vesicles (HDV) as a weight loss compound. HDV is a 20-50 nanometer drug delivery system that is designed to target drugs and nutraceuticals to hepatocytes, the livers metabolic cells.

Diasome Pharmaceuticals has received a worldwide, exclusive license to this technology from SDG, along with technology rights to SDGs platform of hepatic (liver) targeted injectable and oral therapies for diabetes and obesity. Diasomes technologies have received more than $40 million in research and development funding over their history, and the Company has multiple Phase-2 stage human clinical candidates for metabolic conditions in its pipeline.

We are very pleased with the notice of allowance for this novel weight loss technology, said Robert Geho, Diasomes Chief Executive Officer. The HDV system for weight loss can be manufactured for everything from oral capsules to additives to food and beverage products. Being able to move forward with this level of patent protection is very important to our development and commercial strategy.

About Diasome Pharmaceuticals, Inc.

Diasome Pharmaceuticals, Inc. is focused on the clinical and commercial development of breakthrough therapies for diabetes and obesity. Based on more than thirty years of research and development in the fields of cell receptor targeting, insulin replacement, and hepatic (liver) glucose metabolism, the Companys pipeline includes multiple injected and oral formulations of liver targeted insulins for both Type 1 and Type 2 diabetic patients that are Phase 3 ready. In addition, Diasome is developing a first-in-class oral compound for the Type 2 diabetes population that is based upon new insights into normal glucose metabolism and a novel mechanism of action, along with a nanotechnology-based oral compound that may have a significant impact in treating obesity.

Diasomes technology platform is based on the use of its proprietary Hepatocyte Directed Vesicle, or HDV, nanotechnology to deliver a wide range of critically necessary hormones and drugs to the liver, the bodys primary site of glucose storage. It is generally recognized by diabetologists that the currently available forms of injected insulin used by all Type 1 diabetic patients and a significant percentage of people with Type 2 diabetes do not function in the body in the same way as naturally produced insulin. Because insulin tells the body when and how to store glucose, the ideal insulin therapy would function as closely to normal insulin as possible. Diasomes HDV system is designed to fundamentally improve the way in which insulin works in people with diabetes by, for the first time, enabling much greater amounts of injected insulin to reach hepatocytes, the livers glucose storing cells.

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Diasome Pharmaceuticals, Inc. Announces Notice of Allowance for Novel Nanotechnology Weight Loss Patent from the US PTO

Using nanotechnology to improve the speed, efficiency and sensitivity of biosensors

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12 hours ago by Kurt Pfitzer Yongkang Gao (right) and Filbert J. Bartoli took advantage of nanofabrication advances to improve the resolution of their nanoscale biosensors to levels almost as sensitive as those achieved by much larger commercial systems. Credit: Christa Neu

(Phys.org) Over the past half-century, biosensors have opened a new window on the physical world while revolutionizing much of modern society.

By utilizing an electronic or optical system, biosensors detect and interact with the components of biological materials, making it possible to analyze DNA, measure the content of glucose in the blood, detect biotoxins in the water and the atmosphere and much more.

Sales of biosensors reached $8.5 billion worldwide in 2012 and are expected to double to $16.8 by 2018. The United States, with $2.6 billion in sales in 2012, leads the world market.

Yongkang Gao has spent much of the past three years using nanotechnology to improve the speed, efficiency and sensitivity of biosensors while dramatically decreasing their size and cost of operation.

His goal is to transform today's relatively bulky surface plasmon resonance (SPR) biosensors, which take up most of a desktop, into nanoplasmonic biosensors that can be held in the hand and can perform hundreds of testsmedical, environmental or otherat a time.

Gao, who completed his Ph.D. in electrical engineering in January and is now a researcher with Bell labs in New Jersey, is the lead author on an article that a team of Lehigh engineering researchers published recently in the journal Lab on a Chip. The group also contributed the cover image for the issue.

Titled "Plasmonic interferometric sensor arrays for high-performance label-free biomolecular detection," the article was coauthored with Zheming Xin, Beibei Zeng, Qiaoqiang Gan, Xuanhong Cheng and Filbert J. Bartoli. Xin and Zeng are Ph.D. candidates. Gan, who earned his Ph.D. from Lehigh in 2010, is an assistant professor of electrical engineering at the State University of New York at Buffalo. Bartoli, the Chandler Weaver Endowed Chair of Electrical and Computer Engineering, is Gao's Ph.D. adviser and leads the project. Cheng, the P.C. Rossin Assistant Professor in the department of materials science and engineering, is director of Lehigh's Lab of Micro- and Nanotechnology for Diagnostics and Biology.

Improving on the "gold standard"

Scientists have made great progress in recent decades with labeled biosensors that use a receptor attached to a fluorescent molecule to target biomolecules. When bonding occurs between the target and receptor molecules, the fluorescent label emits a light signal whose color provides information about the identities of the two molecules that are bonding and the strength of the bond.

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Using nanotechnology to improve the speed, efficiency and sensitivity of biosensors

Engineering team increases power efficiency for future computer processors

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10 hours ago A picture of spin wave devices, showing magneto-electric cells used for voltage-controlled spin wave generation in the spin wave bus material (yellow stripe). The yellow stripe is about four micrometers in diameter.

(Phys.org) Have you ever wondered why your laptop or smartphone feels warm when you're using it? That heat is a byproduct of the microprocessors in your device using electric current to power computer processing functionsand it is actually wasted energy.

Now, a team led by researchers from the UCLA Henry Samueli School of Engineering and Applied Science has made major improvements in computer processing using an emerging class of magnetic materials called "multiferroics," and these advances could make future devices far more energy-efficient than current technologies.

With today's device microprocessors, electric current passes through transistors, which are essentially very small electronic switches. Because current involves the movement of electrons, this process produces heatwhich makes devices warm to the touch. These switches can also "leak" electrons, making it difficult to completely turn them off. And as chips continue to get smaller, with more circuits packed into smaller spaces, the amount of wasted heat grows.

The UCLA Engineering team used multiferroic magnetic materials to reduce the amount of power consumed by "logic devices," a type of circuit on a computer chip dedicated to performing functions such as calculations. A multiferroic can be switched on or off by applying alternating voltagethe difference in electrical potential. It then carries power through the material in a cascading wave through the spins of electrons, a process referred to as a spin wave bus.

A spin wave can be thought of as similar to an ocean wave, which keeps water molecules in essentially the same place while the energy is carried through the water, as opposed to an electric current, which can be envisioned as water flowing through a pipe, said principal investigator Kang L. Wang, UCLA's Raytheon Professor of Electrical Engineering and director of the Western Institute of Nanoelectronics (WIN).

"Spin waves open an opportunity to realize fundamentally new ways of computing while solving some of the key challenges faced by scaling of conventional semiconductor technology, potentially creating a new paradigm of spin-based electronics," Wang said.

The UCLA researchers were able to demonstrate that using this multiferroic material to generate spin waves could reduce wasted heat and therefore increase power efficiency for processing by up to 1,000 times. Their research is published in the journal Applied Physics Letters.

"Electrical control of magnetism without involving charge currents is a fast-growing area of interest in magnetics research," said co-author Pedram Khalili, a UCLA assistant adjunct professor of electrical engineering. "It can have major implications for future information processing and data-storage devices, and our recent results are exciting in that context."

The researchers previously applied this technology in a similar way to computer memory.

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Molecular Subtyping of Breast Cancer Can Better Identify Women at High Risk of Disease Recurrence

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Newswise A method called molecular subtyping can help doctors better determine which of their breast cancer patients are at high risk of getting breast cancer again, a new study led by the University of South Florida reports. This sophisticated genetic profiling of an individuals specific tumor offers an additional resource to help identify patients who would most benefit from chemotherapy and those who would not.

The findings by researchers from USF and other institutions were presented in a scientific poster at the Miami Breast Cancer Conference, held March 6-9 in Miami Beach, Fla.

The most important takeaway for our colleagues in breast cancer diagnosis and treatment is the potential value of molecular subtyping to personalize and improve each womans treatment, said principal investigator Charles E. Cox, MD, McCann Foundation Endowed Professor of Breast Surgery, USF Health Morsani College of Medicine.

Molecular subtyping is a way of classifying breast cancer tumors into one of four genetically-distinct categories, or subtypes: Luminal A, Luminal B, Basal (a subset of triple negative), and HER2-type. Each subtype responds differently to different kinds of treatments, and some subtypes indicate a higher risk of disease recurrence.

Our data showed that a substantial number of breast cancer patients -- classified as low risk by one particular genomic test -- turn out to be at high risk of recurrence once we determined their subtype, Dr. Cox said. These are mostly Luminal B patients, and their physicians might not fully understand their patients situation unless they do subtyping.

The USF study examined why different genomic tests for breast cancer sometimes provide contradictory information about risk of recurrence. The key findings involved the 70-gene MammaPrint test; the 21-gene Oncotype DX test, which is an earlier commercially available test; and Mammostrat, a gene profiling test performed on slides of the breast tumor by a pathologist. The tests have generally been assumed to provide equivalent information about recurrence risk, but that is proving not to be the case.

Researchers examined tumor samples from a total of 148 patients. The greatest discordance (lack of agreement) about risk of disease recurrence occurred in a group of 51 patients. Of those 51, all were stratified by MammaPrint as high risk of recurrence, while Oncotype classified 18 of them (35 percent) as low risk.

BluePrint, an 80-gene test to identify a tumors molecular subtype, was also used for those stratified by MammaPrint. This process revealed that the 51 patients were Luminal B, a molecular subtype with a high risk of recurrence.

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Molecular Subtyping of Breast Cancer Can Better Identify Women at High Risk of Disease Recurrence

When You Pay for Cloud Storage, Youre Only Paying for Convenience

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What do you get for your money? Thats the question everyone looking to buy a piece of tech asks themselves. It also happens to be the question this recurring feature will try to answer. Is it worth spending extra on high-end gear, or do you get what you need with cheaper models? Every month, well look at some of the cheapest and most expensive products in a given category, testing each to see what their limits are and to help you figure out when you can cheap it out, and when to plunk down some extra cash to get what you need.

I wandered lonely as a cloud, William Wordsworth once wrote, perhaps while pondering the dearth of cloud storage options available in 1802. Today, of course, these services keep our data floating high oer vales and hills on a mesh of connected computers. Because he died in 1850, Wordsworth never had to deal with choosing a cloud storage solution for his collection of musings on daffodils. The rest of us arent so lucky.

Modern hunters of cloud-related bliss have an overwhelming number of solutions, ranging from basic and cheap to feature-rich and expensive. We chose two to look at here: the open-source system ownCloud, and the commercial service Dropbox. We tested ownCloud running on a cheap PC connected to a domestic broadband connection as our free solution. As an open-source project, the software is completely free. Dropbox is also free for most users, but offers a Pro service costing between $10 and $50 per month. This Pro service offers more space (100, 200, or 500GB) for an additional fee.

Both ownClould and Dropbox offer ample space for you to store your stuff. Dropbox starts you off with 2GB, but its easy to get more. They give you, for instance, an additional 250MB for following a simple tutorial, 125MB for each social media account you connect, and 500MB for each friend you refer. With a mixture of these and other bonuses, its easy to get anywhere from 10 to 20 gigabytes of free space, which is enough to store your most vital documents. If you need more, you can also buy space. The upper limit for the Pro version is 500GB for $499 a year, which works out to about a dollar a Gigabyte.

For ownCloud, the limiting factor is the disk space available on the computer it runs on. You can use all of the free space available or just some of it. With hard drive space costing less than 5 cents/GB, that makes it incredibly cheap to build a high-capacity ownCloud server. OwnCloud also doesnt need a lot of processing power to run: You can use anything from a $35 Raspberry Pi up to a multi-core server.

Both services aspire to be much more than places to stash your files; they want to be platforms where you can work with this data as well. Dropbox does this by integrating with other programs through an API (Application Programmers Interface) that allows programmers to integrate Dropbox into their own software. If you use the password manager 1Password, for instance, it can save your password file directly to Dropbox to share between other devices without you having to install the Dropbox software. The simple text editor Writebox allows you to create documents directly in Dropbox, then load and edit them in any web browser. There are also a couple of very basic apps built into the Dropbox site: a photo galley and link manager.

OwnCloud includes a number of built-in plugins like a text editor, calendar, PDF viewer, and contact manager, as well as a large number of apps that add functions like a video streaming server and a music player. These work a little differently than those on Dropbox, though. Most run on the server itself in order to provide the same functions on any web browser. Most of the apps we tried worked adequately, but lacked the polish of the Dropbox apps.

You can upload or download files from a web browser with both services using a client app, synching your essential files in the background while you work. Again, both Dropbox and ownCloud offer a decent selection of clients, supporting Windows, Mac, Linux, iOS and Android. Dropbox has the wider selection, though, with additional support for Blackberry and a number of third-party clients that add extra features, like Boxie.

We found the official clients for both services to be easy to use, automatically uploading files to the cloud as they are created in a designated folder. Dropbox was generally quicker overall, though, because it splits files into chunks and only uploads changed chunks of a file. In contrast, ownCloud has to re-upload the entire file when it is changed, even if only a small part of the file has changed. Adding what the programmers call a delta sync is on the to-do list for the ownCloud development team, but there is no timeline for when this feature will be added. This could be a significant issue if you want to save lots of larger files that change frequently. For people like graphic designers and Photoshop users, Dropbox may be the better option here.

The cloud can be a dangerous place, and Dropbox is not without its flaws in this area. There have been incidents where user data was compromised or left unprotected on the service, and it has had extended outages. Not that ownCloud is exactly perfect here, either. When you run your own server, you are more open to security breaches caused by unpatched problems in other programs, or outages caused by a lost connection. Both services encrypt the data as it is transferred and stored on the server, but Dropbox doesnt allow you to manage this process yourself. OwnCloud does. Its worth noting that self-managed encryption can be added to Dropbox with a third-party app such as BoxCryptor, though.

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When You Pay for Cloud Storage, Youre Only Paying for Convenience

Lady Gaga's Plans For Her SXSW Debut Give Us The Munchies

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Lady Gaga has played in front of every kind of crowd imaginable over the past five-plus years. From dingy New York piano bars to huge festivals and everything in between. But the one thing on her bucket list she's never done is play the annual musical rugby scrum that is the SXSW Festival in Austin, Texas.

But in a video to Little Monsters, Gaga announced that she would be performing on the Born This Way night next Thursday to help kick off the festival.

"I believe being an individual and speaking your mind is one of the boldest things you can do," said Gaga of the gig that will benefit her nonprofit foundation. "And I will be celebrating that with Doritos on Thursday night."

Of course, there's a hitch. As part of the product placement pitch to score tickets to the intimate 2,000-person gig, Monsters have to complete one of the Doritos Bold Mission challenges, which includes #BoldBravery.

In that challenge, interested fans have to upload a picture or video that expresses their individuality through a bold action. "What bold thing have you done that makes you stand out?" Gaga challenged. The singer will pick one winner to be a VIP at the show.

The other challenges include: #BoldLeap, which requires jumping from a 30-foot platform to grab a golden ticket, the #BoldPerformer, in which you need to play a busking set using Doritos-provided instruments and earn $10 in less than 10 minutes and #BoldHaircut, in which the Doritos barber (wait what?) gives you an "electrifying haircut" in front of a crowd.

If those are too wacky, you can also opt for the #BoldSuitcase, in which you turn in your luggage for a Doritos valise and wear whatever is inside to the show, and the #BoldDerby, where you skate one lap against roller derby pros and snatch the flag from the lead jammer ... while wearing an inflatable sumo wrestler suit.

You can enter by either taking on the Bravery challenge, for which Gaga and Doritos will pick the winning entry, or try your hand at one of the other missions on the ground in Austin, because that's only way to score a ticket to the show.

The snack attack gig will serve as a warm-up for the May 4 kick-off of Gaga' upcoming ARTRAVE tour.

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Lady Gaga's Plans For Her SXSW Debut Give Us The Munchies