Liberty Sweeps Presbyterian

From Liberty athletics:

CLINTON, S.C. Catcher Danny Grauer had three hits, including a home run, and right-hander Parker Bean pitched six scoreless innings, as the Liberty Flames shut out the Presbyterian Blue Hose, 8-0, Sunday afternoon at PC Baseball Complex.

Grauer had three hits and scored two runs for the Flames. In the sixth inning, he hit his third home run of the year. The round tipper was the second of back-to-back home runs with first baseman Alex Close.

Bean ran his record to 4-1 on the year. The freshman scattered three hits over six scoreless innings and combined with three other pitchers for the shutout. The right-hander struck out a career-high seven and did not walk a batter.

Liberty moves to 8-1 in Big South Conference play and to 21-7 overall. The Flames have won seven straight games and 15 out of their 16 contests. In addition, Liberty pitching did not allow a run during its three-game series with PC. The Blue Hose fall to 3-6 in conference action and 10-18-1 overall.

Liberty jumped on the scoreboard in the top of the second. Designated hitter Becker Sankey singled and shortstop Dalton Britt walked to lead off the inning. After the next two Flames were retired, left fielder Andrew Yacyk singled sharply to left to score the first run of the contest. Center fielder Ashton Perritt followed by lining a two-run triple to the bottom of the wall in right-center field, giving the Flames a 3-0 edge.

Liberty added a run in the third inning. With one out, second baseman Ryan Seiz singled and moved to third on a single by Sankey. Britt followed with a sacrifice fly, plating Seiz for a 4-0 advantage.

In the sixth, the Flames scored two more runs on the back-to-back home runs by Close and Grauer. With one out, Close yanked the first pitch he saw of his at bat over the left-center field wall for his fourth home run of the year. Grauer followed by ripping a 1-1 offering over the left-center field fence for a 6-0 lead.

Liberty tacked on single runs in the eighth and the ninth. An infield single by right fielder Will Shepherd plated Grauer, who had singled, in the eighth, while a RBI single by Britt in the ninth plated the final run of the game.

PC starter Brian Kehner drops to 0-5 on the season. The left-hander gave up six runs on 10 hits. The first of three Blue Hose pitchers, he struck out two batters and walked one.

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Liberty Sweeps Presbyterian

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Marshall Islands won't give up war on climate change

Rising sea levels and increasing temperatures caused by human activity was a key finding of a seven-year report by a UN panel on climate change released this afternoon.

In the Pacific some low-lying countries could completely disappear, meaning whole populations will have to be relocated to other countries.

One of those is the Marshall Islands, a group of 24 atolls lying just north of the equator halfway between Fiji and Hawaii.

For the 60,000 inhabitants of the country, discussion over whether climate change is real is an insult.

They've been watching their country disappear under rising seawaters for years.

Mack Joel and his wife Tilang have lived in Majuro their entire lives, and they say the island is disappearing fast.

As a child Ms Joel used to play in a park next to a cemetery, where there were trees halfway to the reef. Now, that park has now completely vanished, along with half of the graves.

The latest scientific reports suggest the world is currently heading for a one- to two-metre rise in sea levels by the end of the century. If those predictions are accurate, the Marshall Islands - like many other low lying countries - will be lost forever.

It seems the cruellest of ironies that those most affected by climate change are those who are doing the least to cause it. The Marshallese, like their neighbours in Kiribati and Tuvalu, are mostly subsistence farmers. Their carbon footprint is virtually zero, yet it'll be these people who'll suffer the most.

Vice-President of the Marshall Islands Tony de Brum is an outspoken critic of the big powers' efforts at tackling climate change and is extremely frustrated that his people have nothing to do with the rising waters, and that there is nothing they can do to control it.

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Marshall Islands won't give up war on climate change

CAMH researcher discovers 2 new genes linked to intellectual disability

PUBLIC RELEASE DATE:

31-Mar-2014

Contact: Kate Richards media@camh.ca 416-595-6015 Centre for Addiction and Mental Health

(Toronto) March 31, 2014 Researchers at the Centre for Addiction and Mental Health have discovered two new genes linked to intellectual disability, according to two research studies published concurrently this month in the journals Human Genetics and Human Molecular Genetics.

"Both studies give clues to the different pathways involved in normal neurodevelopment," says CAMH Senior Scientist Dr. John Vincent, who heads the MiND (Molecular Neuropsychiatry and Development) Laboratory in the Campbell Family Mental Health Research Institute at CAMH. "We are building up a body of knowledge that is informing us which kinds of genes are important to, and involved in, intellectual disabilities."

In the first study, Dr. Vincent and his team used microarray genotyping to map the genes of a large Pakistani family which had intermarriage. Five members of the youngest generation were affected with mild to moderate intellectual disability. Dr. Vincent identified a truncation in the FBXO31 gene, which plays a role in the way that proteins are processed during development of neurons, particularly in the cerebellar cortex.

In the second study, using the same techniques, Dr. Vincent and his team analyzed the genes of two families with intermarriage, one Austrian and one Pakistani, and identified a disruption in the METTL23 gene linked to mild recessive intellectual disability. The METTL23 gene is involved in methylationa process important to brain development and function.

About one per cent of children worldwide are affected by non-syndromic (i.e., the absence of any other clinical features) intellectual disability, a condition characterized by an impaired capacity to learn and process new or complex information, leading to decreased cognitive functioning and social adjustment. Although trauma, infection and external damage to the unborn fetus can lead to an intellectual disability, genetic defects are a principal cause.

These studies were part of an ongoing study of affected families in Pakistan, where the cultural tradition of large families and consanguineous (inter-) marriages among first cousins increases the likelihood of inherited intellectual disability in offspring.

"Although it is easier to find and track genes in consanguineous families, these genes are certainly not limited to them," Dr. Vincent points out. A recent study estimated that 13 per cent of intellectual disability cases among individuals of European descent are caused when an individual inherits two recessive genes, meaning that results of this study are very relevant to populations such as Canada.

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CAMH researcher discovers 2 new genes linked to intellectual disability