Old Diaoyu Islands maps go under the hammer

Nineteen old western maps including ones featuring the Diaoyu Islands will be highlights of first day of Xiling Academy of Traditional Arts' spring auction in Hangzhou.

Published from the mid-18th century until 1944 in France, Germany, the United Kingdom and the United States, the maps are currently owned by an European collector and will be sold on May 3, according to Li Qin, spokesperson for the academy. Previews began on Wednesday.

On these maps, the islands to the northeast of Taiwan are marked as "Haoyusu","Tiaoyousou" or "Tyaoyusu", based on the Mandarin Chinese or dialects in use when the maps were made, she said.

On the oldest map, dating back to 1752, a copy of a map drawn by French geographer and cartographer Jean Baptiste Bourguignon d'Anville in 1734, the islands are marked as Haoyusu, or Diaoyu in the Minnan Dialect, Li said.

These items provide fresh evidence that the islands have been Chinese territory since ancient times. Japan annexed the islands in 1895 after the First Sino-Japanese War. They are known as the Senkaku Islands.

Also under the hammer are a collection of documents revealing the Sino-Japanese ties from 1911 to 1932, including correspondence, intelligence documents, official files, memorandums, certificates, and bank statements.

Established in 1904 in the capital of east China's Zhejiang Province, Xiling Academy of Traditional Arts specializes in poetry, calligraphy, painting and engraving, and has the longest history and the most wide influence in the study of seal engraving in China.

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Old Diaoyu Islands maps go under the hammer

Bay of Islands marine reserves long overdue

Bay of Islands marine reserves long overdue

Independent conservation organisation Forest & Bird is welcoming a proposal from a local community group for two marine reserves to be created in the Bay of Islands.

Fish Forever released the proposal at a function last night (Thursday) at the Copthorne Hotel in Waitangi.

Forest & Bird Marine Conservation Advocate Katrina Goddard says the current lack of any marine reserves in the Bay is typical of the poor level of marine protection found throughout New Zealand waters.

The Bay of Islands is hugely popular with tourists, recreational anglers, and boaties, and there is an urgent need to set aside a portion of the area for full marine protection. These reserves would allow significant pockets of marine life to flourish.

Right now, snorkellers in the Bay of Islands commonly see kina barrens vast areas where the absence of crayfish and snapper has allowed kina to multiply, killing off kelp, leaving rocks bare, and starving juvenile fish of important habitats.

Easily accessible marine reserves like those proposed by Fish Forever draw huge numbers of visitors, protect biodiversity and help replenish fish stocks across the wider area, Katrina Goddard says.

More than 380,000 people visit the Goat Island Marine Reserve every year. People fishing outside the marine reserves boundaries are a common sight so its pretty clear there would be more than just conservation benefits to having no-take marine reserves in the Bay of Islands.

Less than one per cent of New Zealands total marine area is protected by marine reserves. We need marine reserves that protect all the various ocean habitats and marine life, whether in deep offshore waters, or in areas like the Bay of Islands.

We hope that plenty of New Zealanders take the opportunity to have their say on Fish Forevers proposal, Katrina Goddard says.

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Bay of Islands marine reserves long overdue

A new syndrome caused by mutations in AHDC1

PUBLIC RELEASE DATE:

1-May-2014

Contact: Glenna Picton picton@bcm.edu 713-798-7973 Baylor College of Medicine

HOUSTON (May 1, 2014) -- A team of researchers led by Baylor College of Medicine have identified the gene underlying a newly recognized genetic syndrome that has symptoms of sleep apnea, delayed speech and hyptonia, or generalized upper body weakness.

The study published online today in the American Journal of Human Genetics.

The Baylor researchers first studied a patient from Australia with these symptoms who had been seen by many doctors and had multiple diagnostic tests, without any diagnosis.

Although there was no family history of the disease, the researchers performed DNA sequence analysis on the patient and her parents to determine if there was an underlying genetic cause for her symptoms.

The results showed damaging mutations had newly arisen in five genes in the patient when compared with the parents DNA sequence.

One gene was a candidate for causing the disease because similar mutations were never seen in healthy control individuals.

"This led us to ask if there were any other undiagnosed disease cases that had similar mutations in this gene," said Dr. Fan Xia, assistant professor of molecular and human genetics and in the Whole Genome Laboratory at Baylor and the first author on the report.

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A new syndrome caused by mutations in AHDC1

Standard & Poor’s U.S. Consumer, Retail, And Health Care Weekly Review (April 28) – Video


Standard Poor #39;s U.S. Consumer, Retail, And Health Care Weekly Review (April 28)
In this segment of U.S. Consumer, Retail, and Health Care Weekly, Standard Poor #39;s Director Linda Phelps discusses the actions we recently took on Zimmer, Pilot Travel Centers, Stater Bros.,...

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Nazarian Family Chiropractic – Los Angeles, CA – Health + Medical – Video


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Nazarian Family Chiropractic - Los Angeles Dr. Victor Nazarian has been in practice in Westwood at the same office for the past 19 years. He is a board certified Doctor of Chiropractic and...

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College of DuPage: First Responders and Health Care Team Collaborative Simulation Exercise 2014 – Video


College of DuPage: First Responders and Health Care Team Collaborative Simulation Exercise 2014
Students from six College of DuPage Health Sciences programs practiced their skills as they responded to a domestic violence simulation that recently was held on campus. The in-depth exercise...

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OPTIMISTIC health care study aims at saving lives, money

INDIANAPOLIS -

Indiana University is undergoing a sizeable effort to improve the quality of care for seniors who live in nursing homes and cut health care costs at the same time.

IU has placed an extra resource, registered nurse Betty Grady at Rosewalk on the east side of Indianapolis.

"I think this is what I was born to be, an optimistic research nurse. I love this. I feel like I can make a difference," Grady said.

She is one of 25 RNs or nurse practitioners with an extra set of eyes on 2,000 patients at 19 central Indiana nursing homes who helped identify an early infection in resident Ola Bluitt.

"I didn't know that I had pneumonia. I knew that I wasn't feeling well and I just couldn't understand what was going on with my body," the 80-year-old resident said.

With new "OPTIMISTIC" protocols, subtle changes in Ola's health were flagged and documented on a new "Stop and Watch" form, which led to more care.

"Because we started the antibiotic early, we were able to catch the pneumonia early and she was able to stay here at home," Grady said.

That's a better option than going to the hospital, where seniors like Ola are more vulnerable to infection and confusion.

"They have long waits when they go through the emergency room. They don't know anyone there, so there is also that fear factor," said Grady.

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OPTIMISTIC health care study aims at saving lives, money

Saskatchewan health care professionals vote to strike

Provincial health care professionals have voted overwhelmingly in favour of job action after failing to sign a contract with the health regions.

The president of the Health Sciences Association of Saskatchewan, Karen Wasylenko, said Thursday that 85 per cent of union members voted to support job action.

Health care employers have only themselves to blame for this situation. They presented a shameful contract proposal last month, which received strong negative reaction from the specialized health care professionals we represent, Wasylenko said in a media release.

Union members voted by mail over the last few weeks. Votes were tallied Wednesday night.

The union represents over 30 different groups and 3,000 workers including paramedics, hospital pharmacists and occupational therapists. They've struggled over the last month to reach a contract agreement with the Saskatchewan Association of Health Organizations.

Wasylenko said staffing levels are the biggest concern for her members.

"We see wait lists that are increasing, we see emergency care services that are becoming unsafe because of staffing," Wasylenko said.

The association's workers went on strike in 2011 during their last round of contract negotiations

Under new labour legislation, the union must take a number of additional steps before a strike notice can be served.

The threat of job action is always a last resort for our health care professionals, Wasylenko said.

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Saskatchewan health care professionals vote to strike

Health care signups in Utah exceed expectations

SALT LAKE CITY (AP) - Utah enrollment in health care plans on the federal website greatly exceeded what the Obama administration expected, according to government figures released Thursday that show the final numbers the first year of the historic health care overhaul.

The 84,600 people who signed up represent a 48 percent increase from the administrations target of 57,000 for the state, the Department of Health and Human Services reported. That includes people allowed to sign up during a two-week extension in April after the March 31 deadline.

The figures indicate there was a huge surge as the deadline approached, with more than half of the total enrollees in Utah signing up during the final weeks.

Enrollment started slowly last fall on an online marketplace plagued by glitches, but it gradually increased with each month.

Nationally, more than 8 million people signed up on the new marketplace.

Utah is one of more than 30 states that left it to the federal government to run its online exchange for individuals to find coverage. The state runs its own exchange for small businesses, which it created in 2009.

A lot of people said Utah isnt going to go for this, but Utahns did, said Jason Stevenson, spokesman for the Utah Health Policy Project, a nonprofit group assisting with enrollment efforts in the state. They liked what they saw on healtcare.gov.

Utah was one of 31 states that met or exceeded enrollment targets set by the administration before the insurance exchanges opened, an Associated Press analysis found. Twenty of those states, including Utah, are led by Republican governors, many of whom were hostile to the program.

One of Utahs critics of the health care overhaul, Republican state Sen. Allen Christensen, said hes still not impressed.

When you dont have any other choice and you are threatened with a fine, most people are going to sign up, said Christensen, a pediatric dentist.

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Health care signups in Utah exceed expectations

Plant Engineers Sow Debate

Today virtually everything we eat is produced from seeds that have been genetically altered in some way. New methods of plant tinkering have emerged over the generations and so, too, have the fears

Today virtually everything we eat is produced from seeds that have been genetically altered in one way or another. Credit: Thinkstock

Editor's note: The following is the introduction to the May 2014 issue of Scientific American Classics: The Birth of the Great GMO Debate.

The idea of intentionally infecting a plant with a bacterium might seem strange. Just three decades ago, however, researchers discovered that they could use this infection to deliver new and potentially useful genes into crops.

What has long appeared to be simply the agent of a bothersome plant disease is likely to become a major tool for the genetic manipulation of plants: for putting new genes into plants and thereby giving rise to new varieties with desired traits, announced acclaimed scientist Mary-Dell Chilton in 1983 in a pioneering article, one of many in this collection from the archives of Scientific American. Today genes introduced this way are yielding some of the most exciting new approaches to food securityas well as a hearty amount of debate.

Despite the excitement about the potential benefits of genetic engineering 30 years ago, the broader historical perspective highlighted in this collection reveals that this is just one of many thrilling and surprising advances in the long history of plant genetic alteration, which began well before this retrospective issue could document. (Scientific American extends back only to 1845.) Consider the assessment of the new technology of cross-pollination described in 1717 by botanist Richard Bradley: A curious person may by this knowledge produce such rare kinds of plants as have not yet been heard of.

For 10,000 years, in fact, we have altered the genetic makeup of our crops. For example, the ancient ancestor of modern corn was created some 6,000 years ago by Native Americans who domesticated a wild plant called teosinte, which looks nothing like a modern corn plant. If humans still depended on this wild relative, we would need hundreds, if not thousands, of times more plantsand acresto replace corn.

Today virtually everything we eat is produced from seeds that have been genetically altered in one way or another. The old approaches were crude and have been refined over the centuries. Modern methods include grafting and forced pollination (mixing genes of distantly related species) and radiation treatments to create random mutations in seeds. The newest method is genetic engineeringa technology developed after scientists observed that the bothersome plant pathogen Agrobacterium tumefaciens habitually introduced its own genes into plants. With a little laboratory work, the bacterium can instead implant desirable genes, such as those that increase nutrients or help the plant resist pests or drought.

The planting of genetically engineered crops during the past 20 years has drastically reduced the amount of synthetic insecticides sprayed worldwide, shifted the use of herbicides to those that are less toxic, rescued the U.S. papaya industry from disease, and benefited the health and well-being of farmers and their families and consumers. Every scientific review of the crops on the market so far has concluded that the plants are safe to eat.

Just as the excitement surrounding the benefits of genetic engineering paralleled those of our predecessors, so, too, has the fear of plant tinkering technologies persisted over time. Consider the comments of Maxwell T. Masters, president of the International Conference of Hybridization, in his 1899 Scientific American article: Many worthy people objected to the production of hybrids on the ground that it was an impious interference with the laws of Nature. Today we are all too familiar with similar arguments about the application of genetic engineering in agriculture.

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Gene discovery links cancer cell 'recycling' system to potential new therapy

PUBLIC RELEASE DATE:

1-May-2014

Contact: Leslie Orr Leslie_Orr@urmc.rochester.edu University of Rochester Medical Center

University of Rochester scientists have discovered a gene with a critical link to pancreatic cancer, and further investigation in mice shows that by blocking the gene's most important function, researchers can slow the disease and extend survival.

Published online by Cell Reports, the finding offers a potential new route to intrude on a cancer that usually strikes quickly, has been stubbornly resistant to targeted therapies, and has a low survival rate. Most recent improvements in the treatment of pancreatic cancer, in fact, are the result of using different combinations of older chemotherapy drugs. The research led by Hartmut "Hucky" Land, Ph.D., and Aram F. Hezel, M.D., of UR Medicine's James P. Wilmot Cancer Center, identifies a new target in the process of garbage recycling that occurs within the cancer cell called autophagy, which is critical to pancreatic cancer progression and growth.

Autophagy is derived from the Greek roots "auto" (self) and "phagein" (to eat), and is an intracellular digestive process that allows cells to survive under stress. During a cell's transformation from normal to malignant, autophagy speeds up to keep pace with rapid cellular changes and a tumor's quest to grow. The newly discovered PLAC-8 gene sustains the highly active recycling process, as it removes faulty proteins and organelles and degrades them into reusable building blocks during cancer progression.

"What makes this an exciting opportunity is that the gene we're studying is critical to the cancer cell's machinery but it is not essential to the function of normal cells," said Land, chair of Biomedical Genetics at the University of Rochester School of Medicine and Dentistry and director of research at Wilmot. "By targeting these types of non-mutated genes that are highly specific to cancer, we are looking for more effective ways to intervene."

The Cell Reports study underlines Wilmot's overall unique approach to cancer research. Rather than investigate single faulty genes linked to single subtypes of cancer, Rochester scientists have identified a larger network of approximately 100 non-mutated genes that cooperate and control the shared activities of many cancers. While investigating this larger gene network, Land and Hezel focused on PLAC-8.

Moreover, the team found that by inactivating PLAC-8 in mice and shutting down autophagy, they could significantly slow cancer's progression. The relevance of PLAC-8 may also extend to other tumors lung, colon, and liver, for example -- that share key genetic changes such as KRAS and p53 mutations that are present in the majority of pancreatic cancers. The breadth of these findings is an area of ongoing study in the Land and Hezel labs.

"PLAC-8 and its job within the cancer cell of accelerating recycling suggests new points of attack and what we all hope will be opportunities to identify and develop new treatments," said Hezel, vice chief of Wilmot's Division of Hematology and Oncology and a UR associate professor. "Our data showing PLAC 8's role in autophagy has great potential because while there are other drugs being evaluated to inhibit autophagy, not all of them target proteins specifically important to this process in tumors."

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Gene discovery links cancer cell 'recycling' system to potential new therapy