Right Knee SVF | Stem Cell Therapy | Stem Cell Injection
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Left Bicep Tendon Injection | Stem Cell Therapy | Stem Cell Injection
Eterna MD specializes in stem cell therapy and treatment. This particular case stem cells were injected into the left bicep tendon through an ultrasound guid...
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Left Subscapularis SVF Injection | Stem Cell Therapy | Stem Cell Injection
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Left Biceps Tendon SVF | Stem Cell Therapy | Stem Cell Injection
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Right AC Joint SVF Injection Shoulder | Stem Cell Therapy | Stem Cell Injection
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Doubts keep growing about the stunning discovery that super stem cells could be created merely by placing white blood cells from young mice in acid or otherwise stressing them, says Paul Knoepfler, a stem cell researcher at UC Davis.
Among other inconsistencies, Knoepfler referred to several unexplained anomalies in images of these STAP cells in two papers, published by the prestigious journal Nature on Jan. 29. One image appears to suggest signs that virtually all cells treated with an acid bath were being reprogrammed, a result that would be extraordinary. Stem cell reprogramming to date has been inefficient, with a low percentage of treated cells being reprogrammed.
"The more I look at these two STAP papers, the more concerned I get ... The bottom line for me now is that some level a part of me still clings to a tiny and receding hope this has all been overblown due to simple misunderstandings, but that seems increasingly unlikely," Knoepfler wrote Sunday on his blog, IPS Cell.
This undated image made available by the journal Nature shows a mouse embryo formed with specially-treated cells from a newborn mouse that had been transformed into stem cells. Researchers in Boston and Japan say they created stem cells from various tissues of newborn mice. If the same technique works for humans, it may provide a new way to grow tissue for treating illnesses like diabetes and Parkinson's disease. The report was published online on Wednesday, Jan. 29, 2014 in the journal Nature. (AP Photo/RIKEN Center for Developmental Biology, Haruko Obokata)
Nature is conducting its own investigation, Knoepfler noted. But in addition, the journal should release "unmodified, original versions" of the images and data in the papers, Knoepfler wrote.
The images contained "minor errors" that didn't change the basic findings, said Charles Vacanti, a Harvard University professor who is part of the scientific team reporting the discovery, according to a Feb. 22 article in a Japanese newspaper, the Asahi Shimbun.
Controversy is normal for any major scientific advance. Skeptics must be converted, and the only way to do that is to show the data. The 1997 announcement of the first mammalian clone, Dolly the sheep, was greeted with considerable doubt because it was believed that genetic imprinting made such cloning impossible. But others were eventually able to confirm the finding.
In this case, doubters say such an apparently easy method of reprogramming cells would generate pluripotent stem cells far too easily, because stress is common in animals. Such stem cells are known to cause tumors, so evolution should have selected against such a response.
Nature's own role has been criticized. The journal was taken to task for its handling of online journalism Feb. 20 by another stem cell blogger, Alexey Bersenev. He chided Nature for not linking to sources.
"In scientific journalism, every claim must be linked to appropriate original source," Berseney wrote. "Nature consistently refuses to acknowledge bloggers, online discussions and other web resources with valid credible information. This is not acceptable for sci journalism."
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Researchers in Bern have discovered that, during a viral infection, immune cells control the blood stem cells in the bone marrow and therefore also the body's own defenses. The findings could allow for new forms of therapy, such as for bone marrow diseases like leukemia.
During a viral infection, the body needs various defense mechanisms -- amongst other things, a large number of white blood cells (leukocytes) must be produced in the bone marrow within a short period of time. In the bone marrow, stem cells are responsible for this task: the blood stem cells. In addition to white blood cells, blood stem cells also produce red blood cells and platelets.
The blood stem cells are located in specialized niches in the bone marrow and are surrounded by specialized niche cells. During an infection, the blood stem cells must complete two tasks: they must first recognise that more blood cells have to be produced and, secondly, they must recognise what kind of.
Now, for the first time, researchers at the Department of Medical Oncology at the University of Bern and Bern University Hospital headed by Prof. Adrian Ochsenbein have investigated how the blood stem cells in the bone marrow are regulated by the immune system's so-called T killer cells during a viral infection. As this regulation mechanism mediated by the immune system also plays an important role in other diseases such as leukemia, these findings could lead to novel therapeutic approaches. The study is being published in the peer-reviewed journal "Cell Stem Cell" today.
T Killer cells trigger defenses
One function of T killer cells is to "patrol" in the blood and remove pathogen-infected cells. However, they also interact with the blood stem cells in the bone marrow. The oncologists in Bern were able to show that messenger substances secreted by the T killer cells modulate the niche cells. In turn, the niche cells control the production and also the differentiation of the blood stem cells.
This mechanism is important in order to fight pathogens such as viruses or bacteria. However, various forms of the bone marrow disease leukemia are caused by a malignant transformation of exactly these blood stem cells. This leads to the formation of so-called leukemia stem cells. In both cases, the mechanisms are similar: the "good" mechanism regulates healthy blood stem cells during an infection, whilst the "bad" one leads to the multiplication of leukemia stem cells. This in turn leads to a progression of the leukemia.
This similarity has already been investigated in a previous project by the same group of researchers. "We hope that this will enable us to better understand and fight infectious diseases as well as bone marrow diseases such as leukemia," says Carsten Riether from the Department of Clinical Research at the University of Bern and the Department of Medical Oncology at Bern University Hospital and the University of Bern.
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The above story is based on materials provided by University of Bern. Note: Materials may be edited for content and length.
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Monday 24 Feb 2014 4:05 AM
Written byELEANOR DICKINSON
Sufferers of serious brain diseases could one day be helped by stem cell treatments , according to scientists at Cambridge University.
Scientists at the University hope to be able to use the regenerative power of stem cells to treat major brain conditions such as Parkinsons and Huntingtons disease.
Their findings are expected to be revealed at the Cambridge Festival of Science next month.
Robin Franklin, the newly appointed Professor of Stem Cell Medicine, will be discussing his research into central nervous system regeneration and the possibility of treating multiple sclerosis.
He said: The brain, although capable of unmatched feats of adaptability, is generally considered to be an organ that is very poor at mending itself after injury.
However, one particular type of brain cell, called the oligodendrocyte the cell that makes the myelin wrapping around nerve fibres can be regenerated when lost in disease by the brains own stem cells.
By studying in the laboratory how brain stem cells generate new oligodendrocytes it has been possible to identify ways in which this important regenerative process might be achieved in the clinic, offering the
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Stem cells to fight brain diseases say Cambridge scientists
Stem Cell Therapy - Studies That Support Regenerative Therapy (Regenexx)
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CLINICell Stem Cell Therapy for Knee Meniscus Tear 1 year Follow-Up
Stem cell therapy for knee post operative interview. This patient came in with a knee meniscus tear and one year after his initial procedure patient is pain ...
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CLINICell Stem Cell Therapy for Knee Meniscus Tear 1 year Follow-Up - Video
Platelet Rich Plasma Prolotherapy injections to the elbow
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Current ratings for: 'Largest ever' trial of adult stem cells in heart attack patients begins
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The largest ever trial of adult stem cell therapy in heart attack patients has begun at The London Chest Hospital in the UK.
Heart disease is the world's leading cause of death. Globally, more than 17 million people died from heart disease last year. In the US, over 1 million people suffer a heart attack each year, and about half of them die.
Heart attacks are usually caused by a clot in the coronary artery, which stops the supply of blood and oxygen to the heart. If the blockage is not treated within a few hours, then it causes the heart muscle to die.
The stem cell trial - titled "The effect of intracoronary reinfusion of bone marrow-derived mononuclear cells (BM-MNC) on allcause mortality in acute myocardial infarction," or "BAMI" for short - has been made possible due to a 5.9 million ($8.1 million) award from the European Commission.
The full study involves 19 partners across France, Germany, Italy, Finland, Denmark, Spain, Belgium, Poland, the Czech Republic and the UK.
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Current ratings for: 'Largest ever' trial of adult stem cells in heart attack patients begins
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The largest ever trial of adult stem cell therapy in heart attack patients has begun at The London Chest Hospital in the UK.
Heart disease is the world's leading cause of death. Globally, more than 17 million people died from heart disease last year. In the US, over 1 million people suffer a heart attack each year, and about half of them die.
Heart attacks are usually caused by a clot in the coronary artery, which stops the supply of blood and oxygen to the heart. If the blockage is not treated within a few hours, then it causes the heart muscle to die.
The stem cell trial - titled "The effect of intracoronary reinfusion of bone marrow-derived mononuclear cells (BM-MNC) on allcause mortality in acute myocardial infarction," or "BAMI" for short - has been made possible due to a 5.9 million ($8.1 million) award from the European Commission.
The full study involves 19 partners across France, Germany, Italy, Finland, Denmark, Spain, Belgium, Poland, the Czech Republic and the UK.
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'Largest ever' trial of adult stem cells in heart attack patients begins
Doctors at a London hospital have started treating heart attack patients with their own stem cells in the largest trial of its kind ever undertaken.
The patients at the London Chest Hospital are among the first of 3000 participants in a Europe-wide study looking at the life-prolonging potential of stem cell therapy.
All will be treated within five days of suffering a heart attack. Stem cells taken from bone marrow will be injected into their hearts in the hope of increasing survival rates by a quarter.
The European Commission has contributed STG4.8 million ($A8.91 million) to the BAMI trial taking place in 10 European countries.
It follows the 'Regenerate' series of three smaller charity-funded studies led by Barts Health NHS Trust consultant cardiologist Professor Anthony Mathur.
'The BAMI study is the biggest and most comprehensive trial of its kind in the world and follows the successful Regenerate trials,' said chief trial co-ordinator Prof Mathur.
'It has taken two years to get to the point where we are ready to accept patients, but we have now reached that stage and we are all very excited.
'Our studies will tell us if adult stem cells from bone marrow can repair damaged hearts and, if so, how these cells should be administered to patients.'
Co-researcher Professor John Martin, from University College London, said: 'This trial brings together a powerful partnership of European doctors and scientists to solve a fundamental problem of importance to all people. It will give an answer about whether adult multi-potential stem cells in their natural environment can treat human disease.'
Stem cells are immature 'mother' cells capable of developing into different tissue types.
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Heart attack stem cell trial starts
Freeport, The Bahamas (PRWEB) February 21, 2014
Okyanos Heart Institute, whose mission it is to bring a new standard of care and a better quality of life to patients with coronary artery disease using adult stem cell therapy, announces CEO Matt Feshbach will present at the STEMSO Conference. He will join a panel to discuss the opportunities available through the new stem cell research and Therapy Act. The conference will be held at the Grand Lucayan Resort in Freeport, Grand Bahamas, February 19-22, 2014. The panel discussion will be Friday, February 21 from 8:45 9:45 a.m.
The conference, titled Bridging the Gap: Research to Point of Care, brings together medical scientists, clinicians, regulatory experts, and investors to discuss progress in the field of research and clinical protocols and the process of taking promising therapies to fight chronic disease to market in a responsible manner.
Friday opening remarks will be delivered by Ian Rolle, President of Grand Bahama Port Authority from 8:30 a.m. to 8:45 a.m. followed by the panel presentation until 9:45 a.m. which, in addition to Rolle will include Feshbach, Mitchell Fuerst, Esq., managing partner, Fuerst, Ittleman, David and Joseph. The panel will be moderated by Arthur K. Parris, Jr. of Parris Whittaker.
"With the passing of the Bahamas Stem Cell Research and Therapy Act, which requires high standards of patient safety and care, we believe the Bahamas is an ideal location to bring internationally-approved, adult stem cell technology to patients with unmet medical needs such as chronic coronary artery disease (CAD), says Feshbach. I am pleased to discuss the opportunities available in the Bahamas with investors, doctors and other stakeholders interested in making the Bahamas a world-class destination for adult stem cell therapy."
The STEMSO 2014 Conference in Freeport, Grand Bahama poses a unique opportunity for medical organizations which focus on adult stem cell-based medical treatments, states Douglas Hammond, president of STEMSO. This conference will provide companies looking to expand their research or clinical practices to offshore locations many good reasons to choose the Bahamas. Those attending will be able to network and view the most advanced research and clinical protocols utilizing autologous and allogeneic stem cells in the world today.
The complete agenda can be found on the organizations website at http://www.stemso.org. Other speakers include stem cell researchers, scientists and practitioners from around the world with leading discoveries in the field, and investors in the healthcare space.
Registration is open for attending and exhibiting on STEMSOs website.
ABOUT OKYANOS HEART INSTITUTE: (Oh key AH nos) Based in Freeport, The Bahamas, Okyanos Heart Institutes mission is to bring a new standard of care and a better quality of life to patients with coronary artery disease using cardiac stem cell therapy. Okyanos adheres to U.S. surgical center standards and is led by Chief Medical Officer Howard T. Walpole Jr., M.D., M.B.A., F.A.C.C., F.S.C.A.I. Okyanos Treatment utilizes a unique blend of stem and regenerative cells derived from ones own adipose (fat) tissue. The cells, when placed into the heart via a minimally-invasive procedure, can stimulate the growth of new blood vessels, a process known as angiogenesis. Angiogenesis facilitates blood flow in the heart, which supports intake and use of oxygen (as demonstrated in rigorous clinical trials such as the PRECISE trial). The literary name Okyanos, the Greek god of rivers, symbolizes restoration of blood flow. For more information, go to http://www.okyanos.com/.
NEW MEDIA CONTENT: Okyanos LinkedIn Page: http://www.linkedin.com/company/okyanos-heart-institute Okyanos Facebook Page: https://www.facebook.com/OKYANOS Okyanos Twitter Page: https://twitter.com/#!/OkyanosHeart Okyanos Google+ Page: https://plus.google.com/+Okyanos/posts Okyanos You Tube Physician Channel: http://www.youtube.com/user/okyanosforphysicians
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Okyanos Heart Institute CEO Matt Feshbach to Speak on Panel at International Stem Cell Society Global Conference
21.02.2014 - (idw) Ruprecht-Karls-Universitt Heidelberg
Heidelberg researchers have been delving into the basic regulatory mechanisms of stem cell differentiation. Using the Drosophila melanogaster fruit fly as a model organism, the team led by Prof. Dr. Ingrid Lohmann at Heidelberg University's Centre for Organismal Studies was able to show how a special developmental gene from the Hox family influences germline stem cells. These cells are responsible for sperm formation. The scientists found that impairment of Hox gene function resulted in prematurely aged sperms. Press Release Heidelberg, 21 February 2014
Fruit Fly Model Organism: How a Developmental Gene Influences Sperm Formation Heidelberg researchers study basic regulatory mechanisms of stem cell differentiation
Heidelberg researchers have been delving into the basic regulatory mechanisms of stem cell differentiation. Using the Drosophila melanogaster fruit fly as a model organism, the team led by Prof. Dr. Ingrid Lohmann at Heidelberg University's Centre for Organismal Studies was able to show how a special developmental gene from the Hox family influences germline stem cells. These cells are responsible for sperm formation. The scientists, working in the Maintenance and Differentiation of Stem Cells in Development and Disease Collaborative Research Centre (CRC 873), found that impairment of Hox gene function resulted in prematurely aged sperms.
As immature somatic cells, stem cells can mature into different types of cells, thus making them responsible for the development of all the tissues and organs in the body. They are also able to repair damaged adult cells. Advancements in medical research have shown that stem cells can be used to treat certain diseases. To fulfil the promise of stem cell therapy, it is important to discover the function of the respective stem cells and understand how they interact with their environment, that is, the surrounding cells and tissues, explains Prof. Lohmann, who heads the Developmental Biology research group at the Centre for Organismal Studies (COS).
This microenvironment, which stabilises and regulates stem cell activity, is called a stem cell niche. The Heidelberg research team investigated the niches in the testis of the fruit fly. The germline stem cells there produce daughter cells that develop into mature sperms. In our studies, we wanted to find out the nature, if any, of the relationship between germline stem cells and the gene Abd-B, states Prof. Lohmann, who further explains that Abd-B belongs to a family of developmental genes referred to as Hox genes. These Hox genes control the activity of a multitude of other genes that are responsible for the early development of an organism.
In CRC 873, funded by the German Research Foundation, medical and biological scientists investigate the basic regulatory mechanisms that control the self-renewal and differentiation of stem cells. Different model organisms like the fruit fly Drosophila melanogaster are used for their research, aimed at decoding the principles of stem cell control with the aim to also apply them to higher forms of life and eventually humans. The research results of Prof. Lohmann and her team were published in the journal Developmental Cell.
Original publication: F. Papagiannouli, L. Schardt, J. Grajcarek, N. Ha, I. Lohmann: The Hox Gene Abd-B Controls Stem Cell Niche Function in the Drosophila Testis. Developmental Cell, Vol 28. Iss 2, 189-202 (27 January 2014), doi: 10.1016/j.devcel.2013.12.016
Internet information: Research group of Ingrid Lohmann: http://www.cos.uni-heidelberg.de/index.php/i.lohmann?l=_e
Contact: Prof. Dr. Ingrid Lohmann Centre for Organismal Studies Phone: +49 6221 54-51312 ingrid.lohmann@bioquant.uni-heidelberg.de
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Fruit Fly Model Organism: How a Developmental Gene Influences Sperm Formation
Laminine Testimonial - Stroke
Laminine is availabe in the Philippines!!! "The Closest Alternative To Stem Cell Therapy..." "The miracle formula from a 9-day-old fertilized hen eggs" For M...
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Laminine Testimonial - Chronic Kidney Disease
Laminine is availabe in the Philippines!!! "The Closest Alternative To Stem Cell Therapy..." "The miracle formula from a 9-day-old fertilized hen eggs" For M...
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Poway, California (PRWEB) February 20, 2014
Four-and-a-half year old Dakota, a German Shepherd from Colorado, is managing the pain from osteoarthritis with the help of stem cell therapy thanks to Mountain Ridge Animal Hospital and Pain Management Center of Lafayette. Dakotas positive results showed almost immediately, and just a few months post stem cell therapy using Vet-Stem, Inc. services, he is doing activities that he has not done for years.
Dakota was diagnosed with hip dysplasia at just three years old, and in less than two years time his owners felt his quality of life had significantly started to deteriorate. Robert Landry, DVM at Mountain Ridge Animal Hospital and Pain Management Center has been doing regenerative cell therapy with Vet-Stem for six years, treating various types of orthopedic issues and arthritis in small animals, and determined Dakota was a good candidate for the procedure.
Dr. Landry began Dakotas procedure on a Tuesday in October by collecting a small sample of fat called the falciform fat pad, which was sent overnight to Vet-Stems lab in San Diego, California. Received the next morning, the lab processed Dakotas fat and created injectable doses of his own stem cells to be overnighted back to Dr. Landry. Thursday Dakota received his hip injections and recovery began.
Dakotas results were almost immediate, Dakotas owners expressed, He moves around with ease now and can even go up and down the stairs. Last week he jumped into the back of my SUV, which he hasn't done in years. Before the stem cell therapy Dakota never wagged his tail, and now he doesnt stop! His quality of life is so much better and he seems truly happier.
Dr. Landry and the team at Mountain Ridge Animal Hospital and Pain Management Center specialize in companion animal health care, striving to provide the highest quality in Veterinary health care and customer service. Some of their specialties are pain management, surgery, and regenerative medicine. By understanding and valuing the special role that pets play in a family Dr. Landry and team are genuine advocates for each pet's health and care.
About Vet-Stem, Inc. Vet-Stem, Inc. was formed in 2002 to bring regenerative medicine to the veterinary profession. The privately held company is working to develop therapies in veterinary medicine that apply regenerative technologies while utilizing the natural healing properties inherent in all animals. As the first company in the United States to provide an adipose-derived stem cell service to veterinarians for their patients, Vet-Stem, Inc. pioneered the use of regenerative stem cells in veterinary medicine. The company holds exclusive licenses to over 50 patents including world-wide veterinary rights for use of adipose derived stem cells. In the last decade over 10,000 animals have been treated using Vet-Stem, Inc.s services, and Vet-Stem is actively investigating stem cell therapy for immune-mediated and inflammatory disease, as well as organ disease and failure. For more on Vet-Stem, Inc. and Veterinary Regenerative Medicine, visit http://www.vet-stem.com or call 858-748-2004.
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Mountain Ridge Animal Hospital and Pain Management Center of Lafayette, Colorado Helps Local Shepherd Manage the Pain ...