STELARA is a prescription medicine approved to treat adults 18 years and older with moderate or severe plaque psoriasis that involves large areas or many areas of their body, who may benefit from taking injections or pills (systemic therapy) or phototherapy (treatment using ultraviolet light alone or with pills).

STELARA is a prescription medicine approved to treat adults 18 years and older with active psoriatic arthritis, either alone or with methotrexate.

STELARA is a 45 mg or 90 mg injection given under the skin as directed by your doctor at weeks 0, 4, and every 12 weeks thereafter. It is administered by a healthcare provider or self-injected only after proper training.

STELARA can make you more likely to get infections or make an infection that you have worse. People who have a genetic problem where the body does not make any of the proteins interleukin 12 (IL-12)Proteins that increase the growth and function of white blood cells, which are found in your immune system. and interleukin 23 (IL-23)Proteins that increase the growth and function of white blood cells, which are found in your immune system. are at a higher risk for certain serious infections that can spread throughout the body and cause death. It is not known if people who take STELARA will get any of these infections because of the effects of STELARA on these proteins.

Cancers

STELARA may decrease the activity of your immune systemA system inside the body that protects against germs and infections. and increase your risk for certain types of cancer. Tell your doctor if you have ever had any type of cancer. Some people who had risk factors for skin cancer developed certain types of skin cancers while receiving STELARA. Tell your doctor if you have any new skin growths.

Reversible posterior leukoencephalopathy syndrome (RPLS)

RPLS is a rare condition that affects the brain and can cause death. The cause of RPLS is not known. If RPLS is found early and treated, most people recover. Tell your doctor right away if you have any new or worsening medical problems including: headache, seizures, confusion, and vision problems.

Serious Allergic Reactions

Serious allergic reactions can occur. Get medical help right away if you have any symptoms such as: feeling faint, swelling of your face, eyelids, tongue, or throat, trouble breathing, throat or chest tightness, or skin rash.

Before receiving STELARA, tell your doctor if you:

When prescribed STELARA:

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit http://www.fda.gov/medwatch or call 1-800-FDA-1088.

Please read the Full Prescribing Information, including the Medication Guide for STELARA, and discuss any questions you have with your doctor.

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What is Psoriasis? STELARA (ustekinumab)

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Psoriasis Journey

By Maureen SalamonHealthDay Reporter FRIDAY, Oct. 9, 2015 (HealthDay News) Psoriasis and cold sores top the list of stigmatized skin conditions, a new survey indicates, but experts say much of the ill will directed at sufferers is misguided. Surveying 56 people, Boston researchers found that nearly 61 percent wrongly thought psoriasis which produces widespread, scaly [...]

By Steven ReinbergHealthDay Reporter THURSDAY, Oct. 8, 2015 (HealthDay News) The skin disorder psoriasis appears linked with artery inflammation, raising the odds for heart disease, a new study says. As the amount of psoriasis increases, the amount of blood vessel inflammation increases, said senior investigator Dr. Nehal Mehta, a clinical investigator with the U.S. National Heart, [...]

Regardless of severity, patients with the often disfiguring skin condition psoriasis face an elevated risk for depression, new research suggests.

By Steven ReinbergHealthDay Reporter WEDNESDAY, Sept. 30, 2015 (HealthDay News) Two experimental drugs show promise in treating psoriasis and a related condition, psoriatic arthritis, new studies report. The drugs, brodalumab and secukinumab (Cosentyx), represent a new approach to treatment, said Michael Siegel, director of research programs at the National Psoriasis Foundation. These studies show how targeting [...]

People with psoriasis may be twice as likely to experience depression as those without the common skin condition, regardless of its severity, a new study suggests.

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Psoriasis Condition Center - Health.com

Menter A, Gottlieb A, Feldman SR, Voorhees ASV, Leonardi CL, Gordon KB, et al. Guidelines for the management of psoriasis and psoriatic arthritis. Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics.Menter A, Gottlieb A, Feldman SR, Voorhees ASV, Leonardi CL, Gordon KB, et al. Guidelines for the management of psoriasis and psoriatic arthritis. Section 1. Overview of psoriasis and guidelines of care for the treatment of psoriasis with biologics. J Am Acad Dermatol. 2008;5:826-850.

Menter A, Korman NJ, Elmets CA, Feldman SR, Gelfand JM, Gordon KB, et al. American Academy of Dermatology guidelines of care for the management of psoriasis and psoriatic arthritis. Section 3. Guidelines of care for the management and treatment of psoriasis with topical therapies.Menter A, Korman NJ, Elmets CA, Feldman SR, Gelfand JM, Gordon KB, et al. American Academy of Dermatology guidelines of care for the management of psoriasis and psoriatic arthritis. Section 3. Guidelines of care for the management and treatment of psoriasis with topical therapies. J Am Acad Dermatol. 2009;60:643-659.

Menter A, Korman NJ, Elments CA, et al. Guidelines of care for the management of psoriasis and psoriatic arthritis.Section 5. Guidelines of care for the treatment of psoriasis with phototherapy and photochemotherapy.Menter A, Korman NJ, Elments CA, et al. Guidelines of care for the management of psoriasis and psoriatic arthritis.Section 5. Guidelines of care for the treatment of psoriasis with phototherapy and photochemotherapy. J Am Acad Dermatol. 2011;1:114-135. Available at: http://www.ncbi.nlm.nih.gov/pubmed/19811850

Psoriasis. Alvero R, Ferri FF, Fort GG, et al, eds. In:Psoriasis. Alvero R, Ferri FF, Fort GG, et al, eds. In: Ferri's Clinical Advisor 2015. 1st ed. Philadelphia, PA: Elsevier Mosby; 2014:section I.

Stern RS. Psoralen and ultraviolet a light therapy for psoriasis.Stern RS. Psoralen and ultraviolet a light therapy for psoriasis. N Engl J Med. 2007;357(7):682-690. Available at: http://www.ncbi.nlm.nih.gov/pubmed/17699818

Weigle N, McBane S. Psoriasis.Weigle N, McBane S. Psoriasis. Am Fam Physician. 2013:87(9);626-633.

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Psoriasis: MedlinePlus enciclopedia mdica

Facts about the skin from DermNet New Zealand Trust. Topic index: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Psoriasis is a chronic inflammatory skin condition characterised by clearly defined, red and scaly plaques (thickened skin). It is classified into several subtypes.

Psoriasis affects 24% of males and females. It can start at any age including childhood, with peaks of onset at 1525 years and 5060 years. It tends to persist lifelong, fluctuating in extent and severity. It is particularly common in Caucasians, but may affect people of any race. About one third of patients with psoriasis have family members with psoriasis.

Psoriasis is multifactorial. It is classified as an immune-mediated inflammatory disease (IMID).

Genetic factors are important. An individual's genetic profile influences their type of psoriasis and its response to treatment.

Genome-wide association studies report that HLA-Cw6 is associated with early onset psoriasis and guttate psoriasis. This major histocompatibility complex is not associated with arthritis, nail dystrophy or late onset psoriasis.

Theories about the causes of psoriasis need to explain why the skin is red, inflamed and thickened. It is clear that immune factors and inflammatory cytokines (messenger proteins) such is IL1 and TNF are responsible for the clinical features of psoriasis. Current theories are exploring the TH17 pathway and release of the cytokine IL17A.

Psoriasis usually presents with symmetrically distributed, red, scaly plaques with well-defined edges. The scale is typically silvery white, except in skin folds where the plaques often appear shiny and they may have a moist peeling surface. The most common sites are scalp, elbows and knees, but any part of the skin can be involved. The plaques are usually very persistent without treatment.

Itch is mostly mild but may be severe in some patients, leading to scratching and lichenification (thickened leathery skin with increased skin markings). Painful skin cracks or fissures may occur.

When psoriatic plaques clear up, they may leave brown or pale marks that can be expected to fade over several months.

Certain features of psoriasis can be categorised to help determine appropriate investigations and treatment pathways. Overlap may occur.

Generalised pustulosis and localised palmoplantar pustulosis are no longer classified within the psoriasis spectrum.

Patients with psoriasis are more likely than other people to have other health conditions listed here.

Psoriasis is diagnosed by its clinical features. If necessary, diagnosis is supported by typical skin biopsy findings.

Medical assessment entails a careful history, examination, questioning about effect of psoriasis on daily life, and evaluation of comorbid factors.

Validated tools used to evaluate psoriasis include:

The severity of psoriasis is classified as mild in 60% of patients, moderate in 30% and severe in 10%.

Evaluation of comorbidities may include:

Patients with psoriasis should ensure they are well informed about their skin condition and its treatment. There are benefits from not smoking, avoiding excessive alcohol and maintaining optimal weight.

Mild psoriasis is generally treated with topical agents alone. Which treatment is selected may depend on body site, extent and severity of the psoriasis.

Most psoriasis centres offer phototherapy with ultraviolet (UV) radiation, often in combination with topical or systemic agents. Types of phototherapy include

Moderate to severe psoriasis warrants treatment with a systemic agent and/or phototherapy. The most common treatments are:

Other medicines occasionally used for psoriasis include:

Systemic corticosteroids are best avoided due to risk of severe withdrawal flare of psoriasis and adverse effects.

Biologics or targeted therapies are reserved for conventional treatment-resistant severe psoriasis, mainly because of expense, as side effects compare favourably with other systemic agents. These include:

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Author:Hon A/Prof Amanda Oakley, Hamilton, New Zealand. Revised and updated, August 2014.

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Psoriasis. DermNet NZ

Psoriasis (say "suh-RY-uh-sus") is a long-term (chronic) skin problem that causes skin cells to grow too quickly, resulting in thick, white, silvery, or red patches of skin.

Normally, skin cells grow gradually and flake off about every 4 weeks. New skin cells grow to replace the outer layers of the skin as they shed.

But in psoriasis, new skin cells move rapidly to the surface of the skin in days rather than weeks. They build up and form thick patches called plaques (say "plax"). The patches range in size from small to large. They most often appear on the knees, elbows, scalp, hands, feet, or lower back. Psoriasis is most common in adults. But children and teens can get it too.

Having psoriasis can be embarrassing, and many people, especially teens, avoid swimming and other situations where patches can show. But there are many types of treatment that can help keep psoriasis under control.

Experts believe that psoriasis occurs when the immune system overreacts, causing inflammation and flaking of skin. In some cases, psoriasis runs in families.

People with psoriasis often notice times when their skin gets worse. Things that can cause these flare-ups include a cold and dry climate, infections, stress, dry skin, and taking certain medicines.

Psoriasis isn't contagious. It can't be spread by touch from person to person.

Symptoms of psoriasis appear in different ways. Psoriasis can be mild, with small areas of rash. When psoriasis is moderate or severe, the skin gets inflamed with raised red areas topped with loose, silvery, scaling skin. If psoriasis is severe, the skin becomes itchy and tender. And sometimes large patches form and may be uncomfortable. The patches can join together and cover large areas of skin, such as the entire back.

In some people, psoriasis causes joints to become swollen, tender, and painful. This is called psoriatic arthritis (say "sor-ee-AT-ik ar-THRY-tus"). This arthritis can also affect the fingernails and toenails, causing the nails to pit, change color, and separate from the nail bed. Dead skin may build up under the nails.

Symptoms often disappear (go into remission), even without treatment, and then return (flare up).

A doctor can usually diagnose psoriasis by looking at the patches on your skin, scalp, or nails. Special tests aren't usually needed.

Most cases of psoriasis are mild, and treatment begins with skin care. This includes keeping your skin moist with creams and lotions. These are often used with other treatments including shampoos, ultraviolet light, and medicines your doctor prescribes.

In some cases, psoriasis can be hard to treat. You may need to try different combinations of treatments to find what works for you. Treatment for psoriasis may continue for a lifetime.

Skin care at home can help control psoriasis. Follow these tips to care for psoriasis:

It's also important to avoid those things that can cause psoriasis symptoms to flare up or make the condition worse. Things to avoid include:

Studies have not found that specific diets can cure or improve the condition, even though some advertisements claim to. For some people, not eating certain foods helps their psoriasis. Most doctors recommend that you eat a balanced diet to be healthy and stay at a healthy weight.

Continued here:

Psoriasis: Healthwise Medical Information on eMedicineHealth

Psoriasis is a chronic skin disorder marked by raised areas of thickened skin and lesions made up of dead skin cells. Psoriasis results from an abnormal process in which new skin cells are made faster than old skin cells are cast off. Psoriasis is linked to an abnormal response of the immune system that causes inflammation. Psoriasis is not contagious.

Symptoms of psoriasis occur in outbreaks and include itchy, red or pink patches of thickened skin that are covered with whitish scales. Psoriasis most often affects the knees, elbows, lower back, and scalp.

Find a Great Dermatologist Near You

There currently is no cure for psoriasis, but the condition can be controlled to minimize outbreaks with an individualized treatment plan that includes lifestyle changes and medications.

Complications of psoriasis can be serious. Complications include psoriatic arthritis and a secondary bacterial infection or fungal infection of the psoriasis rash. Psoriasis is also associated with atherosclerosis, diabetes, and inflammatory bowel disease. Seek prompt medical care if you have symptoms of psoriasis. Early diagnosis and treatment can help reduce the risk for complications of psoriasis and associated conditions.

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Psoriasis - Symptoms, Causes, Treatments - Healthgrades

What is psoriasis?

Psoriasis is a chronic autoimmune skin disease that speeds up the growth cycle of skin cells.

Psoriasis causes patches of thick red skin and silvery scales. Patches are typically found on the elbows, knees, scalp, lower back, face, palms, and soles of feet, but can affect other places (fingernails, toenails, and mouth). The most common type of psoriasis is called plaque psoriasis. Psoriatic arthritis is an inflammatory type of arthritis that eventually occurs in 10% to 20% of people with psoriasis. It is different from more common types of arthritis (such as osteoarthritis or rheumatoid arthritis) and is thought to be related to the underlying problem of psoriasis. Psoriasis and psoriatic arthritis are sometimes considered together as psoriatic disease.

Anyone can get psoriasis. It occurs mostly in adults, but children can also get it. Men and women seem to have equal risk.

Psoriasis is not contagious. This means you cannot get psoriasis from contact (e.g., touching skin patches) with someone who has it.

Psoriasis is an autoimmune disease, meaning that part of the bodys own immune system becomes overactive and attacks normal tissues in the body.

Psoriasis often has a typical appearance that a primary care doctor can recognize, but it can be confused with other skin diseases (like eczema), so a dermatologist (skin doctor) is often the best doctor to diagnose it. The treatment of psoriasis usually depends on how much skin is affected, how bad the disease is (e.g., having many or painful skin patches), or the location (especially the face). Treatments range from creams and ointments applied to the affected areas to ultraviolet light therapy to drugs (such as methotrexate). Many people who have psoriasis also have serious health conditions such as diabetes, heart disease, and depression.

Psoriatic arthritis has many of the same symptoms as other types of arthritis, so a rheumatologist (arthritis doctor) is often the best doctor to diagnose it. The treatment of psoriatic arthritis usually involves the use of drugs (such as methotrexate).

Psoriatic disease (when a person has psoriasis or psoriatic arthritis) may be treated with drugs (such as methotrexate) or a combination of drugs and creams or ointments.

Efforts to address psoriasis and psoriatic arthritis have typically focused on studying and treating individual patients and on clinical and biomedical research. In 2010, CDC worked with experts in psoriasis, psoriatic arthritis, and public health to develop a public health perspective that considers how these conditions affect the entire population. The resulting report is Developing and Addressing the Public Health Agenda for Psoriasis and Psoriatic Arthritis (Agenda)[PDF - 380.44KB]. You can read a short article about the agenda in The American Journal of Preventive Medicine.

CDCs National Health and Nutrition Examination Survey (NHANES) has also included questions about psoriasis to learn more about psoriasis in the United States, which can help in public health research, especially in providing national estimates of how many people have psoriasis (prevalence).

What are other sources for information of psoriasis and psoriatic arthritis?

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CDC - Psoriasis Home Page - Psoriasis

Curing Psoriasis Naturally Week 29, GUESS THE SONG, BLOOD RAIN IS COMING and MORE PENNY TIME
A fantastic week, skin is doing very well. The UK weather has been absolutely stunning this week and the sun has been very warm. This has helped a lot I think, I #39;ve even got a slight tan! ...

By: Jon Maddison

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Curing Psoriasis Naturally Week 29, GUESS THE SONG, BLOOD RAIN IS COMING and MORE PENNY TIME - Video

Curing Psoriasis Naturally Week 28, CHARITY PHOTOSHOOT, PENNY TIME and INVITED TO A CONFERENCE
Fantastic week for skin. Healing is taking place at an incredibly fast rate now. So close to being totally clear and I #39;m very excited. Diet has been mainly fruit this week with some salads...

By: Jon Maddison

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Curing Psoriasis Naturally Week 28, CHARITY PHOTOSHOOT, PENNY TIME and INVITED TO A CONFERENCE - Video

Youngevity 90 for life psoriasis testimony Youve got to see this
These are examples and explanations of Dr Joel Wallachs #39; Youngevity System. Youngevity greatly improved my health, regain my #39;life #39; and smile.... I am using these products and they greatly...

By: I Want To Be Well

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Youngevity 90 for life psoriasis testimony Youve got to see this - Video

Youngevity | Dr Wallach - #39;Cure #39; for Psoriasis
These are examples and explanations of Dr Joel Wallachs #39; Youngevity System. Youngevity greatly improved my health, regain my #39;life #39; and smile.... I am using these products and they greatly...

By: I Want To Be Well

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Youngevity | Dr Wallach - 'Cure' for Psoriasis - Video

Revitol Dermasis Psoriasis Cream - Psoriasis Natural Treatments - Natural Remedies for Psoriasis
GET DISCOUNT http://goo.gl/d7utQ4 revitol dermasis psoriasis cream reviews Pertaining to sufferers experiencing serious psoriasis, a fresh alternative can be acquired , involving injecting...

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Revitol Dermasis Psoriasis Cream - Psoriasis Natural Treatments - Natural Remedies for Psoriasis - Video

Psoriasis Educational Forum
If you or a loved one have psoriasis, join CTT and Dr. Elizabeth Hughes-Tichy for an educational forum today @ 6pm Central.

By: TXClinicalTrials

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Psoriasis Educational Forum - Video

Stubborn Psoriasis vs TWEEZERS!
After lubing up with some coconut oil in my last video, I found this patch on my left ankle.

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Stubborn Psoriasis vs TWEEZERS! - Video

Testimonios jaquecas y psoriasis

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Testimonios jaquecas y psoriasis - Video

How to GET RID of PSORIASIS with a PLANT BASED VEGAN DIET
In this video I explain how you can get rid of psoriasis naturally using a plant based vegan diet and alkalising regime. Things to remove or eliminate: Refined sugar Dairy Meat Eggs Nightshade...

By: Jon Maddison

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How to GET RID of PSORIASIS with a PLANT BASED VEGAN DIET - Video

Coffee Chat: 4-9-15 Q A; Psoriasis, Spring Preps
Hey guys, just a quick coffee chat. Thanks for watching, and God bless. J.

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Coffee Chat: 4-9-15 Q&A; Psoriasis, Spring Preps - Video

By Dennis Thompson HealthDay Reporter Latest Infectious Disease News

WEDNESDAY, April 8, 2015 (HealthDay News) -- An active ingredient in some psoriasis and multiple sclerosis medications has been linked to two cases of a rare and sometimes lethal brain infection.

The ingredient, dimethyl fumarate, appears to have contributed to the deaths of two European women. The women contracted progressive multifocal leukoencephalopathy, or PML, according to two letters published in the April 9 issue of the New England Journal of Medicine.

One case involved a 54-year-old woman with multiple sclerosis. She died in October 2014 from complications related to PML and pneumonia, following 4.5 years of treatment with a time-delayed form of dimethyl fumarate carrying the brand name Tecfidera, researchers reported.

The second case was a 64-year-old woman with psoriasis. She died in August 2014 from PML after being treated with a delayed-release dimethyl fumarate compound with the brand name Psorinovo for two years, according to the researchers.

These cases follow reports linking other drugs containing dimethyl fumarate with PML, including Tysabri and Fumaderm, the researchers said.

However, the latest case reports do not prove that dimethyl fumerate caused the PML infections.

And outside experts said cases of PML occur rarely enough that dimethyl fumarate should remain on the market, as an option for people with MS or psoriasis.

"It's something to be concerned about and something to pay attention to. But from what we know right now, the occurrence of PML appears to be pretty low for Tecfidera," said Bruce Bebo, executive vice president of research for the National Multiple Sclerosis Society.

PML is caused by the JC virus, which normally lies dormant in most people's bodies and causes no harm. But if a person's immune system becomes compromised, the JC virus can flare up and attack the white matter of the brain.

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Ingredient in MS, Psoriasis Drugs Linked to Two Deadly Brain Infections

Bethesda, Maryland (PRWEB) April 09, 2015

CME Outfitters (CMEO), a leading accredited provider in continuing medical education, announces its newest CMEO Medical Simulations, Not Just Skin Deep: Psoriasis Parts I and II. Faculty experts April W. Armstrong, MD, MPH, and Alan Menter, MD guide you through the simulations to improve your knowledge base and clinical management skills in patients with psoriasis, and improve your knowledge of psoriasis comorbidities and clinical strategies to improve long-term patient outcomes. Dermatologists, physicians, and other health care professionals, including pharmacists, nurses, physician assistants, and nurse practitioners who have an interest in psoriasis are encouraged to participate.

Patients with moderate-to-severe psoriasis are at risk for a variety of comorbidities. Dermatologists are in a unique position to screen for these comorbidities and counsel patients to be aware of early symptoms and risk factors. Prevention and early intervention can be achieved by appropriate treatment of psoriasis and reduction of other risk factors contributing to these complications. In this two-part medical simulation, you will meet Lisa, a 45-year-old woman who presents to you feeling very self-conscious about her skin condition, in part one, and has questions about the effects of her skin condition on her overall health, in part two. Navigate through the simulation and Lisas clinical challenges with Dr. Armstrong and Dr. Menter as your guides.

At the end of this activity, participants should be able to:

Click here for more information about the faculty, financial support, credit information, disclosures, and to participate today!

About CME Outfitters, LLC CME Outfitters develops and distributes live, recorded and web-based, outcomes- and evidence-based educational activities to thousands of clinicians each year and offers expert accreditation and outcome services for non-accredited organizations. CME Outfitters focuses on delivering education to specialty audiences, with strong expertise in neuroscience, inflammatory, infectious, and autoimmune diseases, and cardiovascular disease. For a complete list of certified activities and more information, visit http://www.cmeoutfitters.com or call 877.CME.PROS (877.263.7767).

CME Outfitters Improving Clinical Behavior One Change at a Time

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CME Outfitters Two-Part Medical Simulation on Psoriasis Featuring Expert Faculty Commentary Now Available Online

Cara Delevingne interview moments, talking about psoriasis
If you like this video, hit me a big thumbs up and subscribe for me 🙂 and also share it FIND ME INSTAGRAM http://instagram.com/thisiscaradelevingne TWITTER https://twitter.com/saydelevingne...

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